Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc156_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 47 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding 5.744E-8 2.699E-6 1.198E-5 2.699E-6 2 2
2 GO:0034056 estrogen response element binding 3.445E-7 8.097E-6 3.593E-5 1.619E-5 2 4
3 GO:0030284 estrogen receptor activity 5.742E-7 8.995E-6 3.992E-5 2.699E-5 2 5
4 GO:0098531 transcription factor activity, direct ligand regulated sequence-specific DNA binding 7.000E-5 6.580E-4 2.920E-3 3.290E-3 2 50
5 GO:0004879 nuclear receptor activity 7.000E-5 6.580E-4 2.920E-3 3.290E-3 2 50
6 GO:0003707 steroid hormone receptor activity 9.767E-5 7.651E-4 3.396E-3 4.591E-3 2 59
7 GO:0042562 hormone binding 1.938E-4 1.301E-3 5.774E-3 9.107E-3 2 83
8 GO:1903924 estradiol binding 2.679E-4 1.559E-3 6.917E-3 1.259E-2 1 1
9 GO:0005496 steroid binding 2.985E-4 1.559E-3 6.917E-3 1.403E-2 2 103
10 GO:0001046 core promoter sequence-specific DNA binding 3.720E-4 1.748E-3 7.758E-3 1.748E-2 2 115
11 GO:0031798 type 1 metabotropic glutamate receptor binding 5.358E-4 2.289E-3 1.016E-2 2.518E-2 1 2
12 GO:0001047 core promoter binding 7.544E-4 2.955E-3 1.311E-2 3.546E-2 2 164
13 GO:0031404 chloride ion binding 1.339E-3 4.841E-3 2.149E-2
6.294E-2
 1 5
14 GO:1990239 steroid hormone binding 1.607E-3 5.394E-3 2.394E-2
7.552E-2
 1 6
15 GO:0001077 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific 1.867E-3 5.849E-3 2.596E-2
8.773E-2
 2 259
16 GO:0035256 G protein-coupled glutamate receptor binding 2.409E-3 6.989E-3 3.102E-2
1.132E-1
 1 9
17 GO:0030235 nitric-oxide synthase regulator activity 2.677E-3 6.989E-3 3.102E-2
1.258E-1
 1 10
18 GO:0048019 receptor antagonist activity 2.677E-3 6.989E-3 3.102E-2
1.258E-1
 1 10
19 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding 3.211E-3 7.655E-3 3.397E-2
1.509E-1
 1 12
20 GO:0001223 transcription coactivator binding 3.479E-3 7.655E-3 3.397E-2
1.635E-1
 1 13
21 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3.513E-3 7.655E-3 3.397E-2
1.651E-1
 2 357
22 GO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding 3.669E-3 7.655E-3 3.397E-2
1.725E-1
 2 365
23 GO:0030547 receptor inhibitor activity 3.746E-3 7.655E-3 3.397E-2
1.761E-1
 1 14
24 GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding 3.950E-3 7.736E-3 3.433E-2
1.857E-1
 2 379
25 GO:0000987 proximal promoter sequence-specific DNA binding 4.348E-3 8.174E-3 3.628E-2
2.044E-1
 2 398
26 GO:0042975 peroxisome proliferator activated receptor binding 5.081E-3 9.185E-3 4.076E-2
2.388E-1
 1 19
27 GO:0015347 sodium-independent organic anion transmembrane transporter activity 5.615E-3 9.425E-3 4.183E-2
2.639E-1
 1 21
28 GO:0005452 inorganic anion exchanger activity 5.615E-3 9.425E-3 4.183E-2
2.639E-1
 1 21
29 GO:0015301 anion:anion antiporter activity 7.747E-3 1.255E-2
5.571E-2
3.641E-1
 1 29
30 GO:0001221 transcription cofactor binding 8.013E-3 1.255E-2
5.571E-2
3.766E-1
 1 30
31 GO:0043548 phosphatidylinositol 3-kinase binding 1.014E-2 1.538E-2
6.824E-2
4.766E-1
 1 38
32 GO:0035254 glutamate receptor binding 1.227E-2 1.802E-2
7.995E-2
5.765E-1
 1 46
33 GO:0030545 receptor regulator activity 1.359E-2 1.936E-2
8.591E-2
6.388E-1
 1 51
34 GO:0099516 ion antiporter activity 1.465E-2 2.025E-2
8.988E-2
6.886E-1
 1 55
35 GO:0015297 antiporter activity 2.204E-2 2.960E-2
1.314E-1
1.000E0
 1 83
36 GO:0051117 ATPase binding 2.310E-2 3.001E-2
1.332E-1
1.000E0
 1 87
37 GO:0008013 beta-catenin binding 2.362E-2 3.001E-2
1.332E-1
1.000E0
 1 89
38 GO:0043178 alcohol binding 2.965E-2 3.668E-2
1.628E-1
1.000E0
 1 112
39 GO:0015103 inorganic anion transmembrane transporter activity 3.487E-2 4.203E-2
1.865E-1
1.000E0
 1 132
40 GO:0008144 drug binding 3.592E-2 4.220E-2
1.873E-1
1.000E0
 1 136
Show 35 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 335 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0060011 Sertoli cell proliferation 1.210E-6 4.055E-4 2.592E-3 4.055E-4 2 7
2 GO:0060068 vagina development 3.169E-6 5.308E-4 3.393E-3 1.062E-3 2 11
3 GO:0030540 female genitalia development 8.808E-6 8.907E-4 5.694E-3 2.951E-3 2 18
4 GO:0060009 Sertoli cell development 1.094E-5 8.907E-4 5.694E-3 3.664E-3 2 20
5 GO:0060065 uterus development 1.329E-5 8.907E-4 5.694E-3 4.453E-3 2 22
6 GO:0060008 Sertoli cell differentiation 2.019E-5 1.011E-3 6.460E-3 6.763E-3 2 27
7 GO:0071392 cellular response to estradiol stimulus 3.035E-5 1.011E-3 6.460E-3 1.017E-2 2 33
8 GO:0015721 bile acid and bile salt transport 3.035E-5 1.011E-3 6.460E-3 1.017E-2 2 33
9 GO:0060740 prostate gland epithelium morphogenesis 3.035E-5 1.011E-3 6.460E-3 1.017E-2 2 33
10 GO:0060512 prostate gland morphogenesis 3.419E-5 1.011E-3 6.460E-3 1.145E-2 2 35
11 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 3.419E-5 1.011E-3 6.460E-3 1.145E-2 2 35
12 GO:1901186 positive regulation of ERBB signaling pathway 3.620E-5 1.011E-3 6.460E-3 1.213E-2 2 36
13 GO:0048662 negative regulation of smooth muscle cell proliferation 4.709E-5 1.214E-3 7.758E-3 1.578E-2 2 41
14 GO:0046942 carboxylic acid transport 5.517E-5 1.244E-3 7.952E-3 1.848E-2 3 333
15 GO:0015849 organic acid transport 5.717E-5 1.244E-3 7.952E-3 1.915E-2 3 337
16 GO:0071391 cellular response to estrogen stimulus 5.941E-5 1.244E-3 7.952E-3 1.990E-2 2 46
17 GO:0030520 intracellular estrogen receptor signaling pathway 7.028E-5 1.308E-3 8.362E-3 2.354E-2 2 50
18 GO:0048806 genitalia development 7.028E-5 1.308E-3 8.362E-3 2.354E-2 2 50
19 GO:0030850 prostate gland development 9.150E-5 1.613E-3 1.031E-2 3.065E-2 2 57
20 GO:0015711 organic anion transport 1.462E-4 2.448E-3 1.565E-2 4.896E-2 3 462
21 GO:0001541 ovarian follicle development 1.546E-4 2.466E-3 1.576E-2
5.178E-2
 2 74
22 GO:0042058 regulation of epidermal growth factor receptor signaling pathway 2.041E-4 3.107E-3 1.986E-2
6.836E-2
 2 85
23 GO:1901184 regulation of ERBB signaling pathway 2.187E-4 3.186E-3 2.037E-2
7.327E-2
 2 88
24 GO:0097254 renal tubular secretion 2.685E-4 3.598E-3 2.300E-2
8.994E-2
 1 1
25 GO:1990375 baculum development 2.685E-4 3.598E-3 2.300E-2
8.994E-2
 1 1
26 GO:0022602 ovulation cycle process 3.417E-4 4.403E-3 2.815E-2
1.145E-1
 2 110
27 GO:0008585 female gonad development 4.481E-4 5.084E-3 3.250E-2
1.501E-1
 2 126
28 GO:0048660 regulation of smooth muscle cell proliferation 4.697E-4 5.084E-3 3.250E-2
1.573E-1
 2 129
29 GO:0046545 development of primary female sexual characteristics 4.843E-4 5.084E-3 3.250E-2
1.622E-1
 2 131
30 GO:0007173 epidermal growth factor receptor signaling pathway 4.917E-4 5.084E-3 3.250E-2
1.647E-1
 2 132
31 GO:0048659 smooth muscle cell proliferation 4.991E-4 5.084E-3 3.250E-2
1.672E-1
 2 133
32 GO:0030518 intracellular steroid hormone receptor signaling pathway 5.218E-4 5.084E-3 3.250E-2
1.748E-1
 2 136
33 GO:1903925 response to bisphenol A 5.369E-4 5.084E-3 3.250E-2
1.799E-1
 1 2
34 GO:0044752 response to human chorionic gonadotropin 5.369E-4 5.084E-3 3.250E-2
1.799E-1
 1 2
35 GO:0042698 ovulation cycle 5.372E-4 5.084E-3 3.250E-2
1.800E-1
 2 138
36 GO:0097306 cellular response to alcohol 5.608E-4 5.084E-3 3.250E-2
1.879E-1
 2 141
37 GO:0046546 development of primary male sexual characteristics 5.767E-4 5.084E-3 3.250E-2
1.932E-1
 2 143
38 GO:0008584 male gonad development 5.767E-4 5.084E-3 3.250E-2
1.932E-1
 2 143
39 GO:0046660 female sex differentiation 6.011E-4 5.163E-3 3.301E-2
2.014E-1
 2 146
40 GO:0038127 ERBB signaling pathway 6.427E-4 5.263E-3 3.364E-2
2.153E-1
 2 151
41 GO:0032355 response to estradiol 6.512E-4 5.263E-3 3.364E-2
2.182E-1
 2 152
42 GO:0022612 gland morphogenesis 6.598E-4 5.263E-3 3.364E-2
2.210E-1
 2 153
43 GO:0046661 male sex differentiation 8.041E-4 5.620E-3 3.593E-2
2.694E-1
 2 169
44 GO:0015718 monocarboxylic acid transport 8.041E-4 5.620E-3 3.593E-2
2.694E-1
 2 169
45 GO:0015742 alpha-ketoglutarate transport 8.053E-4 5.620E-3 3.593E-2
2.698E-1
 1 3
46 GO:0060523 prostate epithelial cord elongation 8.053E-4 5.620E-3 3.593E-2
2.698E-1
 1 3
47 GO:0071000 response to magnetism 8.053E-4 5.620E-3 3.593E-2
2.698E-1
 1 3
48 GO:0071259 cellular response to magnetism 8.053E-4 5.620E-3 3.593E-2
2.698E-1
 1 3
49 GO:0006367 transcription initiation from RNA polymerase II promoter 8.618E-4 5.892E-3 3.767E-2
2.887E-1
 2 175
50 GO:2000377 regulation of reactive oxygen species metabolic process 8.815E-4 5.906E-3 3.776E-2
2.953E-1
 2 177
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 17 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043204 perikaryon 5.431E-4 9.232E-3 3.175E-2 9.232E-3 2 142
2 GO:0035327 transcriptionally active chromatin 5.497E-3 4.673E-2
1.607E-1
9.345E-2
 1 21

4: Human Phenotype [Display Chart] 2 input genes in category / 88 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 5 input genes in category / 675 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0008984 vagina hypoplasia 5.595E-7 3.777E-4 2.679E-3 3.777E-4 2 3
2 MP:0001356 increased aggression towards females 2.796E-6 4.609E-4 3.269E-3 1.887E-3 2 6
3 MP:0009856 failure of ejaculation 3.914E-6 4.609E-4 3.269E-3 2.642E-3 2 7
4 MP:0013616 decreased volumetric bone mineral density 5.217E-6 4.609E-4 3.269E-3 3.522E-3 2 8
5 MP:0008983 small vagina 5.217E-6 4.609E-4 3.269E-3 3.522E-3 2 8
6 MP:0009362 abnormal primary ovarian follicle morphology 6.706E-6 4.609E-4 3.269E-3 4.527E-3 2 9
7 MP:0009257 dilated seminiferous tubules 8.381E-6 4.609E-4 3.269E-3 5.657E-3 2 10
8 MP:0010967 increased compact bone area 8.381E-6 4.609E-4 3.269E-3 5.657E-3 2 10
9 MP:0013613 abnormal volumetric bone mineral density 8.381E-6 4.609E-4 3.269E-3 5.657E-3 2 10
10 MP:0001884 mammary gland alveolar hyperplasia 8.381E-6 4.609E-4 3.269E-3 5.657E-3 2 10
11 MP:0009081 thin uterus 8.381E-6 4.609E-4 3.269E-3 5.657E-3 2 10
12 MP:0008977 abnormal vagina size 8.381E-6 4.609E-4 3.269E-3 5.657E-3 2 10
13 MP:0004348 long femur 1.024E-5 4.609E-4 3.269E-3 6.913E-3 2 11
14 MP:0001378 abnormal ejaculation 1.024E-5 4.609E-4 3.269E-3 6.913E-3 2 11
15 MP:0030823 increased femur size 1.024E-5 4.609E-4 3.269E-3 6.913E-3 2 11
16 MP:0006416 abnormal rete testis morphology 1.229E-5 5.184E-4 3.677E-3 8.294E-3 2 12
17 MP:0003357 impaired granulosa cell differentiation 1.694E-5 6.725E-4 4.769E-3 1.143E-2 2 14
18 MP:0009648 abnormal superovulation 1.954E-5 7.327E-4 5.196E-3 1.319E-2 2 15
19 MP:0003862 decreased aggression towards males 2.845E-5 8.942E-4 6.342E-3 1.921E-2 2 18
20 MP:0009304 increased retroperitoneal fat pad weight 2.845E-5 8.942E-4 6.342E-3 1.921E-2 2 18
21 MP:0013795 abnormal colon goblet cell morphology 3.179E-5 8.942E-4 6.342E-3 2.146E-2 2 19
22 MP:0001121 uterus hypoplasia 3.179E-5 8.942E-4 6.342E-3 2.146E-2 2 19
23 MP:0010968 decreased compact bone area 3.179E-5 8.942E-4 6.342E-3 2.146E-2 2 19
24 MP:0013793 abnormal large intestine goblet cell morphology 3.179E-5 8.942E-4 6.342E-3 2.146E-2 2 19
25 MP:0002044 increased colon adenoma incidence 4.292E-5 1.159E-3 8.220E-3 2.897E-2 2 22
26 MP:0008869 anovulation 5.571E-5 1.446E-3 1.026E-2 3.761E-2 2 25
27 MP:0010966 abnormal compact bone area 6.516E-5 1.629E-3 1.155E-2 4.398E-2 2 27
28 MP:0004905 decreased uterus weight 7.016E-5 1.633E-3 1.158E-2 4.736E-2 2 28
29 MP:0006262 increased testis tumor incidence 7.016E-5 1.633E-3 1.158E-2 4.736E-2 2 28
30 MP:0001132 absent mature ovarian follicles 9.199E-5 1.940E-3 1.376E-2
6.209E-2
 2 32
31 MP:0008868 abnormal granulosa cell morphology 9.199E-5 1.940E-3 1.376E-2
6.209E-2
 2 32
32 MP:0003355 decreased ovulation rate 9.199E-5 1.940E-3 1.376E-2
6.209E-2
 2 32
33 MP:0002680 decreased corpora lutea number 9.790E-5 1.944E-3 1.379E-2
6.609E-2
 2 33
34 MP:0003863 decreased aggression towards mice 9.790E-5 1.944E-3 1.379E-2
6.609E-2
 2 33
35 MP:0009506 abnormal mammary gland alveolus morphology 1.234E-4 2.380E-3 1.688E-2
8.329E-2
 2 37
36 MP:0001751 increased circulating luteinizing hormone level 1.372E-4 2.445E-3 1.734E-2
9.264E-2
 2 39
37 MP:0009505 abnormal mammary gland lobule morphology 1.444E-4 2.445E-3 1.734E-2
9.749E-2
 2 40
38 MP:0002790 decreased circulating follicle stimulating hormone level 1.444E-4 2.445E-3 1.734E-2
9.749E-2
 2 40
39 MP:0009363 abnormal secondary ovarian follicle morphology 1.444E-4 2.445E-3 1.734E-2
9.749E-2
 2 40
40 MP:0009285 increased gonadal fat pad weight 1.518E-4 2.445E-3 1.734E-2
1.025E-1
 2 41
41 MP:0001353 increased aggression towards mice 1.518E-4 2.445E-3 1.734E-2
1.025E-1
 2 41
42 MP:0002736 abnormal nociception after inflammation 1.594E-4 2.445E-3 1.734E-2
1.076E-1
 2 42
43 MP:0004903 abnormal uterus weight 1.594E-4 2.445E-3 1.734E-2
1.076E-1
 2 42
44 MP:0005133 increased luteinizing hormone level 1.594E-4 2.445E-3 1.734E-2
1.076E-1
 2 42
45 MP:0005337 abnormal retroperitoneal fat pad morphology 1.750E-4 2.569E-3 1.822E-2
1.182E-1
 2 44
46 MP:0004695 increased length of long bones 1.750E-4 2.569E-3 1.822E-2
1.182E-1
 2 44
47 MP:0008883 abnormal enterocyte proliferation 1.999E-4 2.785E-3 1.975E-2
1.349E-1
 2 47
48 MP:0001129 impaired ovarian folliculogenesis 1.999E-4 2.785E-3 1.975E-2
1.349E-1
 2 47
49 MP:0008874 decreased physiological sensitivity to xenobiotic 2.022E-4 2.785E-3 1.975E-2
1.365E-1
 3 287
50 MP:0005656 decreased aggression 2.086E-4 2.815E-3 1.997E-2
1.408E-1
 2 48
Show 45 more annotations

6: Domain [Display Chart] 5 input genes in category / 30 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR024178 Oest rcpt/oest-rel rcp InterPro 5.696E-7 1.709E-5 6.827E-5 1.709E-5 2 5
2 PS00031 NUCLEAR REC DBD 1 PROSITE 5.870E-5 1.744E-4 6.969E-4 1.761E-3 2 46
3 IPR001628 Znf hrmn rcpt InterPro 5.870E-5 1.744E-4 6.969E-4 1.761E-3 2 46
4 IPR001723 Nuclear hrmn rcpt InterPro 5.870E-5 1.744E-4 6.969E-4 1.761E-3 2 46
5 PF00105 zf-C4 Pfam 5.870E-5 1.744E-4 6.969E-4 1.761E-3 2 46
6 PS51030 NUCLEAR REC DBD 2 PROSITE 5.870E-5 1.744E-4 6.969E-4 1.761E-3 2 46
7 SM00399 ZnF C4 SMART 5.870E-5 1.744E-4 6.969E-4 1.761E-3 2 46
8 1.10.565.10 - Gene3D 6.130E-5 1.744E-4 6.969E-4 1.839E-3 2 47
9 IPR000536 Nucl hrmn rcpt lig-bd InterPro 6.396E-5 1.744E-4 6.969E-4 1.919E-3 2 48
10 SM00430 HOLI SMART 6.396E-5 1.744E-4 6.969E-4 1.919E-3 2 48
11 PF00104 Hormone recep Pfam 6.396E-5 1.744E-4 6.969E-4 1.919E-3 2 48
12 3.30.50.10 - Gene3D 9.041E-5 2.161E-4 8.632E-4 2.712E-3 2 57
13 IPR013088 Znf NHR/GATA InterPro 9.363E-5 2.161E-4 8.632E-4 2.809E-3 2 58
14 IPR024736 Oestrogen-typ rcpt final C dom InterPro 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
15 PF12497 ERbeta N Pfam 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
16 IPR021064 Estrogen rcpt beta N InterPro 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
17 PF15048 OSTbeta Pfam 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
18 PF12743 ESR1 C Pfam 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
19 IPR029387 OSTbeta InterPro 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
20 PF02159 Oest recep Pfam 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
21 IPR028355 ER-beta/gamma InterPro 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
22 IPR001292 Oestr rcpt InterPro 2.669E-4 3.639E-4 1.454E-3 8.006E-3 1 1
23 PF03619 Solute trans a Pfam 1.067E-3 1.334E-3 5.329E-3 3.202E-2 1 4
24 IPR005178 Ostalpha/TMEM184C InterPro 1.067E-3 1.334E-3 5.329E-3 3.202E-2 1 4
25 IPR004749 Orgcat transp/SVOP InterPro 2.400E-3 2.880E-3 1.150E-2
7.200E-2
 1 9
26 IPR000324 VitD rcpt InterPro 3.731E-3 4.305E-3 1.720E-2
1.119E-1
 1 14
27 IPR005828 MFS sugar transport-like InterPro 9.572E-3 1.026E-2 4.097E-2
2.872E-1
 1 36
28 PF00083 Sugar tr Pfam 9.572E-3 1.026E-2 4.097E-2
2.872E-1
 1 36
29 PS50850 MFS PROSITE 2.850E-2 2.948E-2
1.178E-1
8.549E-1
 1 108
30 IPR020846 MFS dom InterPro 3.526E-2 3.526E-2
1.409E-1
1.000E0
 1 134
Show 25 more annotations

7: Pathway [Display Chart] 5 input genes in category / 32 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PW:0000507 estrogen signaling Pathway Ontology 1.290E-7 4.129E-6 1.676E-5 4.129E-6 2 2
2 138009 Plasma membrane estrogen receptor signaling BioSystems: Pathway Interaction Database 4.178E-5 6.684E-4 2.713E-3 1.337E-3 2 26
3 1269652 Nuclear Receptor transcription pathway BioSystems: REACTOME 1.632E-4 1.741E-3 7.067E-3 5.224E-3 2 51
4 814182 Prolactin signaling pathway BioSystems: KEGG 3.082E-4 2.030E-3 8.237E-3 9.864E-3 2 70
5 193146 Bile secretion BioSystems: KEGG 3.171E-4 2.030E-3 8.237E-3 1.015E-2 2 71
6 1404799 Endocrine resistance BioSystems: KEGG 5.796E-4 2.761E-3 1.120E-2 1.855E-2 2 96
7 799177 Estrogen signaling pathway BioSystems: KEGG 6.039E-4 2.761E-3 1.120E-2 1.933E-2 2 98
8 1435207 Breast cancer BioSystems: KEGG 1.299E-3 5.194E-3 2.108E-2 4.155E-2 2 144
9 PW:0000383 multispecific organic anion transporter mediated transport Pathway Ontology 1.606E-3 5.709E-3 2.317E-2
5.138E-2
 1 4
10 1269938 Organic anion transport BioSystems: REACTOME 2.007E-3 6.422E-3 2.606E-2
6.422E-2
 1 5
11 1427841 TFAP2 (AP-2) family regulates transcription of growth factors and their receptors BioSystems: REACTOME 6.410E-3 1.709E-2
6.938E-2
2.051E-1
 1 16
12 1269936 Organic cation/anion/zwitterion transport BioSystems: REACTOME 6.410E-3 1.709E-2
6.938E-2
2.051E-1
 1 16
13 M225 Downregulated of MTA-3 in ER-negative Breast Tumors MSigDB C2 BIOCARTA (v6.0) 7.608E-3 1.873E-2
7.601E-2
2.435E-1
 1 19
14 M18719 Role of ERBB2 in Signal Transduction and Oncology MSigDB C2 BIOCARTA (v6.0) 8.806E-3 2.013E-2
8.169E-2
2.818E-1
 1 22
15 1269499 Nuclear signaling by ERBB4 BioSystems: REACTOME 1.000E-2 2.134E-2
8.659E-2
3.200E-1
 1 25
16 138062 Signaling events mediated by HDAC Class II BioSystems: Pathway Interaction Database 1.358E-2 2.287E-2
9.282E-2
4.346E-1
 1 34
17 138012 Signaling mediated by p38-alpha and p38-beta BioSystems: Pathway Interaction Database 1.398E-2 2.287E-2
9.282E-2
4.473E-1
 1 35
18 M2499 CARM1 and Regulation of the Estrogen Receptor MSigDB C2 BIOCARTA (v6.0) 1.398E-2 2.287E-2
9.282E-2
4.473E-1
 1 35
19 137935 FOXM1 transcription factor network BioSystems: Pathway Interaction Database 1.477E-2 2.287E-2
9.282E-2
4.728E-1
 1 37
20 1427863 Ovarian tumor domain proteases BioSystems: REACTOME 1.477E-2 2.287E-2
9.282E-2
4.728E-1
 1 37
21 1427839 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors BioSystems: REACTOME 1.596E-2 2.287E-2
9.282E-2
5.108E-1
 1 40
22 137957 LKB1 signaling events BioSystems: Pathway Interaction Database 1.676E-2 2.287E-2
9.282E-2
5.362E-1
 1 42
23 1269496 Signaling by ERBB4 BioSystems: REACTOME 1.715E-2 2.287E-2
9.282E-2
5.489E-1
 1 43
24 137979 FOXA1 transcription factor network BioSystems: Pathway Interaction Database 1.715E-2 2.287E-2
9.282E-2
5.489E-1
 1 43
25 213307 Endocrine and other factor-regulated calcium reabsorption BioSystems: KEGG 1.874E-2 2.398E-2
9.733E-2
5.996E-1
 1 47
26 137987 Regulation of Telomerase BioSystems: Pathway Interaction Database 2.623E-2 3.228E-2
1.310E-1
8.394E-1
 1 66
27 137963 Regulation of nuclear SMAD2/3 signaling BioSystems: Pathway Interaction Database 3.055E-2 3.621E-2
1.469E-1
9.775E-1
 1 77
28 1269923 Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds BioSystems: REACTOME 4.186E-2 4.784E-2
1.941E-1
1.000E0
 1 106
Show 23 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 4829 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 29085224 Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
2 15644335 Negative regulation of RANKL-induced osteoclastic differentiation in RAW264.7 Cells by estrogen and phytoestrogens. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
3 18053221 Impact of estrogen receptor gene polymorphisms and mRNA levels on obesity and lipolysis--a cohort study. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
4 15254780 CpG methylation of the ERalpha and ERbeta genes in breast cancer. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
5 17633471 [Estrogen receptors in pelvic floor for female stress urinary incontinence]. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
6 19003958 17Beta-estradiol regulation of the mRNA expression of T-type calcium channel subunits: role of estrogen receptor alpha and estrogen receptor beta. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
7 12207170 Estrogen receptor-alpha and estrogen receptor-beta are present in the human growth plate in childhood and adolescence, in identical distribution. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
8 24833090 Association of promoter methylation of ERα and ERβ with sporadic breast cancer--a study from North India. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
9 18644836 Influence of cellular ERalpha/ERbeta ratio on the ERalpha-agonist induced proliferation of human T47D breast cancer cells. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
10 12710997 Kinetic analysis of estrogen receptor homo- and heterodimerization in vitro. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
11 18497332 Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
12 12727987 Differential regulation of proteasome-dependent estrogen receptor alpha and beta turnover in cultured human uterine artery endothelial cells. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
13 28373182 Energy Balance Modulation Impacts Epigenetic Reprogramming, ERα and ERβ Expression, and Mammary Tumor Development in MMTV-neu Transgenic Mice. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
14 14976146 Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in mouse brain. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
15 21344398 Human sperm physiology: estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) influence sperm metabolism and may be involved in the pathophysiology of varicocele-associated male infertility. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
16 11593044 Increased anxiety and synaptic plasticity in estrogen receptor beta -deficient mice. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
17 22295107 Alternate estrogen receptors promote invasion of inflammatory breast cancer cells via non-genomic signaling. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
18 19574173 Mutation-prone positions within the estrogen receptor. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
19 22895361 A role for estrogen receptor-α and estrogen receptor-β in collagen biosynthesis in mouse skin. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
20 19654868 Genetic polymorphisms of estrogen receptors alpha and beta and the risk of developing prostate cancer. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
21 19771170 Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
22 29390981 Selective oestrogen receptor antagonists inhibit oesophageal cancer cell proliferation in vitro. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
23 15060164 Identification of tamoxifen-induced coregulator interaction surfaces within the ligand-binding domain of estrogen receptors. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
24 27003997 Epithelial turnover in duodenal familial adenomatous polyposis: A possible role for estrogen receptors? Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
25 21586296 Estrogen receptors and gonadal steroids in vulnerability and protection of dopamine neurons in a mouse model of Parkinson's disease. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
26 19897598 Genome-wide dynamics of chromatin binding of estrogen receptors alpha and beta: mutual restriction and competitive site selection. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
27 12827494 Combined lack of estrogen receptors alpha and beta affects vascular iNOS protein expression. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
28 20427709 Estrogen receptor mediates the effects of pseudoprotodiocsin on adipogenesis in 3T3-L1 cells. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
29 18569528 Estrogen receptors alpha (ESR1) and beta (ESR2) are expressed in circulating human lymphocytes. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
30 19959825 Estrogen receptor alpha and beta polymorphisms are associated with semen quality. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
31 19382890 Bioassays for estrogenic activity: development and validation of estrogen receptor (ERalpha/ERbeta) and breast cancer proliferation bioassays to measure serum estrogenic activity in clinical studies. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
32 19032364 Loss of estrogen receptor beta isoform expression and its correlation with aberrant DNA methylation of the 5'-untranslated region in human epithelial ovarian carcinoma. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
33 15086524 Comparison of in vivo and in vitro subcellular localization of estrogen receptors alpha and beta in oligodendrocytes. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
34 11773069 Differential modulation of DNA conformation by estrogen receptors alpha and beta. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
35 15108352 Estrogen stimulates differentiation of megakaryocytes and modulates their expression of estrogen receptors alpha and beta. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
36 21866462 Reed-Sternberg cells in classical Hodgkin lymphoma in children seem to be predominantly oestrogen receptor α negative and oestrogen receptor β positive. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
37 20596625 Prognostic significance and clinical importance of estrogen receptor alpha and beta in human endometrioid adenocarcinomas. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
38 15664447 Sex specific expression of progesterone receptor in mouse lower urinary tract. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
39 12021200 Estrogen promotes early osteoblast differentiation and inhibits adipocyte differentiation in mouse bone marrow stromal cell lines that express estrogen receptor (ER) alpha or beta. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
40 11557741 Effects of estrogen on the vascular injury response in estrogen receptor alpha, beta (double) knockout mice. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
41 17895504 Estrogen receptor alpha and beta gene polymorphisms are not risk factors for recurrent miscarriage in a Brazilian population. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
42 18825402 Expression of both oestrogen receptor alpha and beta in human skeletal muscle tissue. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
43 9473491 The complete primary structure of human estrogen receptor beta (hER beta) and its heterodimerization with ER alpha in vivo and in vitro. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
44 17524430 Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3K-dependent pathways. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
45 25609169 Dual suppression of estrogenic and inflammatory activities for targeting of endometriosis. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
46 22374427 Evaluation of ER-α, ER-Î?1 and ER-Î?2 expression and correlation with clinicopathologic factors in invasive luminal subtype breast cancers. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
47 15545229 Mechanisms of naringenin-induced apoptotic cascade in cancer cells: involvement of estrogen receptor alpha and beta signalling. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
48 16357058 Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
49 22672467 Effect of oestrogen receptors on brain NMDA receptors of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
50 19927160 Association between ESR1 and ESR2 gene polymorphisms and hyperlipidemia in Chinese Han postmenopausal women. Pubmed 1.371E-8 1.485E-7 1.345E-6 6.621E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 4 input genes in category / 2750 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:NCAM2 NCAM2 interactions 8.038E-7 1.263E-3 1.073E-2 2.211E-3 2 7
2 int:PRR12 PRR12 interactions 1.378E-6 1.263E-3 1.073E-2 3.789E-3 2 9
3 int:NCOA7 NCOA7 interactions 1.378E-6 1.263E-3 1.073E-2 3.789E-3 2 9
4 int:KLK9 KLK9 interactions 2.525E-6 1.736E-3 1.475E-2 6.945E-3 2 12
5 int:WIPI1 WIPI1 interactions 4.017E-6 1.868E-3 1.587E-2 1.105E-2 2 15
6 int:MYLK2 MYLK2 interactions 6.540E-6 1.868E-3 1.587E-2 1.798E-2 2 19
7 int:CBLL1 CBLL1 interactions 6.540E-6 1.868E-3 1.587E-2 1.798E-2 2 19
8 int:TRIM59 TRIM59 interactions 7.266E-6 1.868E-3 1.587E-2 1.998E-2 2 20
9 int:THEM6 THEM6 interactions 8.030E-6 1.868E-3 1.587E-2 2.208E-2 2 21
10 int:TRAM1 TRAM1 interactions 8.030E-6 1.868E-3 1.587E-2 2.208E-2 2 21
11 int:ARID5A ARID5A interactions 8.030E-6 1.868E-3 1.587E-2 2.208E-2 2 21
12 int:PNRC2 PNRC2 interactions 8.832E-6 1.868E-3 1.587E-2 2.429E-2 2 22
13 int:SHOC2 SHOC2 interactions 8.832E-6 1.868E-3 1.587E-2 2.429E-2 2 22
14 int:PSMC3IP PSMC3IP interactions 1.055E-5 1.892E-3 1.607E-2 2.902E-2 2 24
15 int:ATAD2 ATAD2 interactions 1.147E-5 1.892E-3 1.607E-2 3.154E-2 2 25
16 int:HIST1H2BD HIST1H2BD interactions 1.147E-5 1.892E-3 1.607E-2 3.154E-2 2 25
17 int:BRI3BP BRI3BP interactions 1.242E-5 1.892E-3 1.607E-2 3.416E-2 2 26
18 int:NCCRP1 NCCRP1 interactions 1.242E-5 1.892E-3 1.607E-2 3.416E-2 2 26
19 int:BUD13 BUD13 interactions 1.342E-5 1.892E-3 1.607E-2 3.689E-2 2 27
20 int:NR2F6 NR2F6 interactions 1.445E-5 1.892E-3 1.607E-2 3.973E-2 2 28
21 int:CSRP1 CSRP1 interactions 1.445E-5 1.892E-3 1.607E-2 3.973E-2 2 28
22 int:DNTTIP2 DNTTIP2 interactions 1.777E-5 2.057E-3 1.748E-2 4.886E-2 2 31
23 int:ATP9A ATP9A interactions 1.895E-5 2.057E-3 1.748E-2
5.211E-2
 2 32
24 int:POLR2K POLR2K interactions 1.895E-5 2.057E-3 1.748E-2
5.211E-2
 2 32
25 int:NR0B1 NR0B1 interactions 2.143E-5 2.057E-3 1.748E-2
5.893E-2
 2 34
26 int:UTP3 UTP3 interactions 2.143E-5 2.057E-3 1.748E-2
5.893E-2
 2 34
27 int:GSTM3 GSTM3 interactions 2.273E-5 2.057E-3 1.748E-2
6.250E-2
 2 35
28 int:SLC25A24 SLC25A24 interactions 2.273E-5 2.057E-3 1.748E-2
6.250E-2
 2 35
29 int:DECR1 DECR1 interactions 2.406E-5 2.057E-3 1.748E-2
6.617E-2
 2 36
30 int:ASCC1 ASCC1 interactions 2.406E-5 2.057E-3 1.748E-2
6.617E-2
 2 36
31 int:AKAP13 AKAP13 interactions 2.406E-5 2.057E-3 1.748E-2
6.617E-2
 2 36
32 int:REXO4 REXO4 interactions 2.406E-5 2.057E-3 1.748E-2
6.617E-2
 2 36
33 int:TFF1 TFF1 interactions 2.544E-5 2.057E-3 1.748E-2
6.995E-2
 2 37
34 int:KDM5A KDM5A interactions 2.544E-5 2.057E-3 1.748E-2
6.995E-2
 2 37
35 int:KDM4B KDM4B interactions 2.830E-5 2.161E-3 1.837E-2
7.781E-2
 2 39
36 int:PATZ1 PATZ1 interactions 2.830E-5 2.161E-3 1.837E-2
7.781E-2
 2 39
37 int:ZBTB17 ZBTB17 interactions 3.287E-5 2.257E-3 1.918E-2
9.039E-2
 2 42
38 int:TCF20 TCF20 interactions 3.447E-5 2.257E-3 1.918E-2
9.480E-2
 2 43
39 int:SRA1 SRA1 interactions 3.447E-5 2.257E-3 1.918E-2
9.480E-2
 2 43
40 int:MKNK2 MKNK2 interactions 3.447E-5 2.257E-3 1.918E-2
9.480E-2
 2 43
41 int:AGFG1 AGFG1 interactions 3.447E-5 2.257E-3 1.918E-2
9.480E-2
 2 43
42 int:TIA1 TIA1 interactions 3.447E-5 2.257E-3 1.918E-2
9.480E-2
 2 43
43 int:EIF4G3 EIF4G3 interactions 3.611E-5 2.257E-3 1.918E-2
9.930E-2
 2 44
44 int:TAF1B TAF1B interactions 3.611E-5 2.257E-3 1.918E-2
9.930E-2
 2 44
45 int:TXNRD1 TXNRD1 interactions 3.779E-5 2.259E-3 1.919E-2
1.039E-1
 2 45
46 int:APOD APOD interactions 3.779E-5 2.259E-3 1.919E-2
1.039E-1
 2 45
47 int:MED25 MED25 interactions 3.950E-5 2.263E-3 1.923E-2
1.086E-1
 2 46
48 int:SEC61B SEC61B interactions 3.950E-5 2.263E-3 1.923E-2
1.086E-1
 2 46
49 int:NSD1 NSD1 interactions 4.125E-5 2.315E-3 1.967E-2
1.134E-1
 2 47
50 int:DNAJC9 DNAJC9 interactions 4.304E-5 2.321E-3 1.972E-2
1.184E-1
 2 48
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 14q23.2 14q23.2 2.882E-3 7.555E-3 1.725E-2 1.441E-2 1 20
2 11q12.3 11q12.3 5.470E-3 7.555E-3 1.725E-2 2.735E-2 1 38
3 6q25.1 6q25.1 5.614E-3 7.555E-3 1.725E-2 2.807E-2 1 39
4 15q22.31 15q22.31 6.044E-3 7.555E-3 1.725E-2 3.022E-2 1 42
5 3q29 3q29 1.277E-2 1.277E-2 2.917E-2
6.387E-2
 1 89

11: Transcription Factor Binding Site [Display Chart] 3 input genes in category / 43 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 5 input genes in category / 2 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 71 Nuclear hormone receptors genenames.org 7.069E-5 9.832E-5 1.475E-4 1.414E-4 2 49
2 752 Solute carriers genenames.org 9.832E-5 9.832E-5 1.475E-4 1.966E-4 3 395

13: Coexpression [Display Chart] 5 input genes in category / 347 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19266279-TableA Human Breast Chen09 20genes GeneSigDB 2.241E-7 7.778E-5 4.999E-4 7.778E-5 2 4
2 M1827 Genes important for preovulatory follicle, based on mouse models with female fertility defects. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.680E-6 2.915E-4 1.874E-3 5.830E-4 2 10
3 M7371 Genes methylated aberrantly in HCT116 and Colo320 (colon cancer) cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.309E-5 1.407E-3 9.041E-3 4.541E-3 2 27
4 M10861 Genes affected by epigenetic aberrations in prostate cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.621E-5 1.407E-3 9.041E-3 5.626E-3 2 30
5 15606925-Table3 Human Breast Bieche04 47genes GeneSigDB 3.852E-5 2.674E-3 1.719E-2 1.337E-2 2 46
6 18221536-Table1 Human Breast Roll08 64genes GeneSigDB 5.523E-5 3.194E-3 2.053E-2 1.916E-2 2 55
7 15899800-TableS1 Human Breast Martens05 117genes GeneSigDB 2.468E-4 1.223E-2
7.863E-2
8.563E-2
 2 116
8 19930681-Table2-4 Human Breast Cecco09 2genes GeneSigDB 4.322E-4 1.875E-2
1.205E-1
1.500E-1
 1 2
9 16536878-SuppTable2 Human Breast Muggerud06 232genes GeneSigDB 5.540E-4 1.951E-2
1.254E-1
1.922E-1
 2 174
10 M2714 Genes up-regulated in primary epithelial breast cancer cell culture over-expressing SRC [Gene ID=6714] gene. MSigDB C6: Oncogenic Signatures (v6.0) 6.125E-4 1.951E-2
1.254E-1
2.125E-1
 2 183
11 15525570-SuppTable1 Human Ovarian Rae04 209genes GeneSigDB 6.669E-4 1.951E-2
1.254E-1
2.314E-1
 2 191
12 M8171 Genes down-regulated in HEK293 cells: expressing mutant NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 1.951E-2
1.254E-1
2.486E-1
 2 198
13 M8311 Genes down-regulated in naïve T cells: CD4 [GeneID=920] versus NK. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.951E-2
1.254E-1
2.536E-1
 2 200
14 16536878-SuppTable1 Human Breast Muggerud06 271genes GeneSigDB 1.165E-3 2.889E-2
1.857E-1
4.044E-1
 2 253
15 19695104-AF1-1 Human Breast Lin09 8genes GeneSigDB 1.512E-3 3.334E-2
2.143E-1
5.246E-1
 1 7
16 M14791 Genes down-regulated in colorectal adenoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.537E-3 3.334E-2
2.143E-1
5.335E-1
 2 291
17 20460173-ImmPortCytokineReceptors Human Immune Kong10 308genes ImmPort CytokineReceptors GeneSigDB 1.665E-3 3.399E-2
2.185E-1
5.779E-1
 2 303
18 19723662-SupplTable2 Human Breast Culhane09 12genes MolecularSubtype GeneSigDB 2.591E-3 4.609E-2
2.962E-1
8.990E-1
 1 12
19 17224074-Table1 Human Breast Chanock07 16genes GeneSigDB 2.806E-3 4.609E-2
2.962E-1
9.738E-1
 1 13
20 18278552-Genes Human Breast Li09 24genes GeneSigDB 2.806E-3 4.609E-2
2.962E-1
9.738E-1
 1 13
21 M19805 Genes whose expression in a panel of lymphoblastoid cell lines was associated with cytotoxicity of the anti-cancer analogs of cytidine, gemcitabine and cytarabine [PubChem=596;3461;6253]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.238E-3 4.609E-2
2.962E-1
1.000E0
 1 15
22 14737112-Table2 Human Breast Treff04 15genes HMGA1 GeneSigDB 3.238E-3 4.609E-2
2.962E-1
1.000E0
 1 15
23 M12322 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 3. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.238E-3 4.609E-2
2.962E-1
1.000E0
 1 15
24 M1351 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 48 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.290E-3 4.609E-2
2.962E-1
1.000E0
 2 428
25 M19779 Cluster 6: selected luminal genes clustered together across breast cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.453E-3 4.609E-2
2.962E-1
1.000E0
 1 16
26 19930681-Table2-3 Human Breast Cecco09 17genes GeneSigDB 3.453E-3 4.609E-2
2.962E-1
1.000E0
 1 16
27 17023159-Table3 Human Breast Nimeus-Malmstrom06 20genes GeneSigDB 3.884E-3 4.677E-2
3.006E-1
1.000E0
 1 18
28 M17115 Genes encoding substrates of IkappaB kinase (IKK) complex. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.884E-3 4.677E-2
3.006E-1
1.000E0
 1 18
29 15591335-GeneList Human Breast Paik04 21genes GeneSigDB 4.530E-3 4.677E-2
3.006E-1
1.000E0
 1 21
30 16536878-SuppTable4 Human Breast Muggerud06 27genes LuminalvNonLuminal GeneSigDB 4.530E-3 4.677E-2
3.006E-1
1.000E0
 1 21
31 15489895-Table5 Human Pancreas Fukushima04 23genes GeneSigDB 4.961E-3 4.677E-2
3.006E-1
1.000E0
 1 23
32 15467746-Table2 Human Bone Ohali04 23genes GeneSigDB 4.961E-3 4.677E-2
3.006E-1
1.000E0
 1 23
33 M2332 Genes translationally up-regulated by serum in MEF cells (embryonic fibroblast) lacking TSC1 [GeneID=7248]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.961E-3 4.677E-2
3.006E-1
1.000E0
 1 23
34 16239301-Table3 Human Breast Harvell 25genes GeneSigDB 4.961E-3 4.677E-2
3.006E-1
1.000E0
 1 23
35 M17086 Genes up-regulated in microdissected endothelial samples from ovarian cancer tumors with tumor-infiltrating lymphocytes (TIL) vs those without TILs. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.176E-3 4.677E-2
3.006E-1
1.000E0
 1 24
36 17711579-Table2a Human Testicular Duale07 24genes GeneSigDB 5.176E-3 4.677E-2
3.006E-1
1.000E0
 1 24
37 17899371-25GeneList Human Breast Lauss08 25genes GeneSigDB 5.176E-3 4.677E-2
3.006E-1
1.000E0
 1 24
38 19930681-Table2-1 Human Breast Cecco09 28genes GeneSigDB 5.391E-3 4.677E-2
3.006E-1
1.000E0
 1 25
39 15501955-Table1 Human Breast Bieche04 29genes invasive GeneSigDB 5.391E-3 4.677E-2
3.006E-1
1.000E0
 1 25
40 16965636-Figure5 Human Breast Kapp06 30genes GeneSigDB 5.391E-3 4.677E-2
3.006E-1
1.000E0
 1 25
41 17711579-Table1a Human Testicular Duale07 26genes GeneSigDB 5.607E-3 4.745E-2
3.050E-1
1.000E0
 1 26
42 M1233 Genes showing frequent DNA methylation and which are silenced in adult cancers but remain unmethylated in embryonic carcinoma and embryonic stem (ES) cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.822E-3 4.810E-2
3.092E-1
1.000E0
 1 27
43 16715129-Table2 Human HeadandNeck Jarvinen06 40genes GeneSigDB 7.327E-3 4.964E-2
3.191E-1
1.000E0
 1 34
44 19074895-SuppTable4 Human Liver Sakai08 36genes GeneSigDB 7.327E-3 4.964E-2
3.191E-1
1.000E0
 1 34
45 M1955 Genes with intermediate-CpG-density promoters (ICP) bearing the bivalent trimethylation marks at H3K4 (H3K4me3) and H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.327E-3 4.964E-2
3.191E-1
1.000E0
 1 34
46 17069663-Table4 Human Breast Hannemann06 43genes DCIS differentiation GeneSigDB 7.327E-3 4.964E-2
3.191E-1
1.000E0
 1 34
47 M18299 Genes up-regulated in early primary breast tumors expressing ESR1 [GeneID=2099] vs the ESR1 negative ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.756E-3 4.964E-2
3.191E-1
1.000E0
 1 36
48 M15473 Selected genes down-regulated in peripheral blood monocytes (PBMC) of patients with hepatocellular carcinoma (HCC) compared to those with chronic hepatitis. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.756E-3 4.964E-2
3.191E-1
1.000E0
 1 36
49 17724462-Table1 Human StemCell Nuytten08 44genes GeneSigDB 8.186E-3 4.964E-2
3.191E-1
1.000E0
 1 38
50 M4988 Genes whose expression was increased due to copy number gain in laryngeal cancer tumors (both in primary cultures and cell lines). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.615E-3 4.964E-2
3.191E-1
1.000E0
 1 40
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 255 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 gudmap developingKidney e15.5 early proxim tubul 1000 k5 DevelopingKidney e15.5 early proxim tubul emap-28005 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.137E-5 2.899E-3 1.774E-2 2.899E-3 3 230
2 gudmap developingKidney e15.5 early proxim tubul 500 DevelopingKidney e15.5 early proxim tubul emap-28005 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 5.638E-5 4.538E-3 2.777E-2 1.438E-2 3 393
3 gudmap kidney single cell adult RenalCortexMixed Scamp k4 500 kidney single cell adult RenalCortexMixed StemCellamp k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 5.638E-5 4.538E-3 2.777E-2 1.438E-2 3 393
4 gudmap kidney adult RenalCortexMixed Std 500 kidney adult RenalCortexMixed Std top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 7.118E-5 4.538E-3 2.777E-2 1.815E-2 3 425
5 gudmap developingKidney e15.5 early proxim tubul 500 k5 DevelopingKidney e15.5 early proxim tubul emap-28005 k-means-cluster#5 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.227E-4 9.735E-3
5.958E-2
5.679E-2
 2 104
6 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup6/Calb1 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup6/Calb1 BrainMap 2.291E-4 9.735E-3
5.958E-2
5.841E-2
 1 1
7 cervix, uterine cervix, uterine Human Protein Atlas 4.566E-4 1.096E-2
6.706E-2
1.164E-1
 2 149
8 gudmap developingGonad e18.5 epididymis 100 k1 DevelopingGonad e18.5 epididymis emap-13166 k-means-cluster#1 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 4.581E-4 1.096E-2
6.706E-2
1.168E-1
 1 2
9 gudmap kidney single cell adult RenalCortexMixed Scamp k3 200 kidney single cell adult RenalCortexMixed StemCellamp k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 4.627E-4 1.096E-2
6.706E-2
1.180E-1
 2 150
10 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup8/Nefm BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup8/Nefm BrainMap 4.814E-4 1.096E-2
6.706E-2
1.227E-1
 2 153
11 Sample Type by Project: Shred 1/TCGA-Bile Duct/Cholangiocarcinoma/Intrahepatic/5/2 Sample Type by Project: Shred 1/TCGA-Bile Duct/Cholangiocarcinoma/Intrahepatic/5/2 TCGA-Bile Duct 5.328E-4 1.096E-2
6.706E-2
1.359E-1
 2 161
12 gudmap kidney single cell adult RenalCortexMixed Scamp 200 kidney single cell adult RenalCortexMixed StemCellamp top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 5.527E-4 1.096E-2
6.706E-2
1.409E-1
 2 164
13 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Overall Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Overall Top 200 Genes Mouse Cell Atlas 6.219E-4 1.096E-2
6.706E-2
1.586E-1
 2 174
14 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Large Intestine/enterocyte of epithelium of large intestine Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Large Intestine/enterocyte of epithelium of large intestine Tabula Muris Consortium 6.506E-4 1.096E-2
6.706E-2
1.659E-1
 2 178
15 PCBC ratio MESO-15 from-ESC vs MESO-15 from-OSK-L-l-p53KD cfr-2X-p05 Mesoderm Day 15-reprogram NA vs Mesoderm Day 15-reprogram OSK-L-l-p53KD-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 6.875E-4 1.096E-2
6.706E-2
1.753E-1
 2 183
16 PCBC ratio MESO-15 from-ESC vs MESO-15 from-episomal cfr-2X-p05 Mesoderm Day 15-method NA vs Mesoderm Day 15-method episomal-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 6.875E-4 1.096E-2
6.706E-2
1.753E-1
 2 183
17 gudmap developingKidney e15.5 Proximal Tubules 1000 k4 DevelopingKidney e15.5 Proximal Tubules emap-28005 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 8.782E-4 1.298E-2
7.942E-2
2.240E-1
 2 207
18 gudmap developingGonad P2 epididymis 100 k2 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 9.160E-4 1.298E-2
7.942E-2
2.336E-1
 1 4
19 gudmap kidney adult RenalCortexMixed Std k2 500 kidney adult RenalCortexMixed Std k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.267E-3 1.700E-2
1.041E-1
3.231E-1
 2 249
20 gudmap developingKidney e14.5 whole kidney - wildtype 1000 k5 DevelopingKidney e14.5 whole kidney - wildtype emap-6674 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.455E-3 1.846E-2
1.130E-1
3.709E-1
 2 267
21 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Duodenum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Duodenum Top 200 Genes Mouse Cell Atlas 1.520E-3 1.846E-2
1.130E-1
3.876E-1
 2 273
22 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Ileum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Ileum Top 200 Genes Mouse Cell Atlas 1.621E-3 1.879E-2
1.150E-1
4.133E-1
 2 282
23 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 FrontalCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 FrontalCortex Top 200 Genes BrainMap 1.868E-3 1.993E-2
1.220E-1
4.763E-1
 2 303
24 gudmap kidney adult JuxtaGlom Ren1 k4 1000 kidney adult JuxtaGlom Ren1 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.892E-3 1.993E-2
1.220E-1
4.826E-1
 2 305
25 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Jejunum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Jejunum Top 200 Genes Mouse Cell Atlas 1.954E-3 1.993E-2
1.220E-1
4.983E-1
 2 310
26 duodenum duodenum Human Protein Atlas 2.093E-3 2.050E-2
1.255E-1
5.338E-1
 2 321
27 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Hippocampus/Hippocampus/Endothelial Tip BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Hippocampus/Hippocampus/Endothelial Tip BrainMap 2.289E-3 2.050E-2
1.255E-1
5.836E-1
 1 10
28 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/SubstantiaNigra/SubstantiaNigra/Endothelial Tip BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/SubstantiaNigra/SubstantiaNigra/Endothelial Tip BrainMap 2.289E-3 2.050E-2
1.255E-1
5.836E-1
 1 10
29 small intestine small intestine Human Protein Atlas 2.331E-3 2.050E-2
1.255E-1
5.945E-1
 2 339
30 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter CD8 T cell/Ureter Normal RCC CD8 T cell/Ureter Normal RCC IT2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter CD8 T cell/Ureter Normal RCC CD8 T cell/Ureter Normal RCC IT2 Adult, Development, and Cancer types 2.517E-3 2.140E-2
1.310E-1
6.419E-1
 1 11
31 gudmap developingGonad P2 ovary 100 k5 DevelopingGonad P2 ovary emap-30224 k-means-cluster#5 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 3.203E-3 2.586E-2
1.583E-1
8.167E-1
 1 14
32 gudmap kidney adult JuxtaGlom Ren1 500 kidney adult JuxtaGlom Ren1 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.245E-3 2.586E-2
1.583E-1
8.275E-1
 2 401
33 gudmap kidney adult JuxtaGlom Ren1 Captopr k2 1000 kidney adult JuxtaGlom Ren1 Captopr k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.928E-3 3.036E-2
1.858E-1
1.000E0
 2 442
34 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal-Cortex Wilms PT-U/Kidney Normal-Cortex Wilms PT13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal-Cortex Wilms PT-U/Kidney Normal-Cortex Wilms PT13 Adult, Development, and Cancer types 4.117E-3 3.087E-2
1.890E-1
1.000E0
 1 18
35 Sample Type by Project: Shred 1/TCGA-Cervix/Cervical Carcinoma/Keratinizing Cervical Squamous Cell Carcinoma/4/1 Sample Type by Project: Shred 1/TCGA-Cervix/Cervical Carcinoma/Keratinizing Cervical Squamous Cell Carcinoma/4/1 TCGA-Cervix 4.345E-3 3.166E-2
1.937E-1
1.000E0
 1 19
36 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Top 200 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Top 200 Mouse Cell Atlas 4.505E-3 3.191E-2
1.953E-1
1.000E0
 2 474
37 gudmap kidney adult RenalCortexMixed Std k1 1000 kidney adult RenalCortexMixed Std k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.674E-3 3.221E-2
1.972E-1
1.000E0
 2 483
38 gudmap developingGonad e16.5 epididymis 100 k3 DevelopingGonad e16.5 epididymis emap-29702 k-means-cluster#3 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 5.029E-3 3.289E-2
2.013E-1
1.000E0
 1 22
39 Sample Type by Project: Shred 1/TCGA-Kidney/Renal Cell Carcinoma/Kidney Clear Cell Renal Carcinoma/1/1 Sample Type by Project: Shred 1/TCGA-Kidney/Renal Cell Carcinoma/Kidney Clear Cell Renal Carcinoma/1/1 TCGA-Kidney 5.029E-3 3.289E-2
2.013E-1
1.000E0
 1 22
40 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter Nephron epithelium/Ureter Normal RCC Nephron epithelium/Ureter Normal RCC N5 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter Nephron epithelium/Ureter Normal RCC Nephron epithelium/Ureter Normal RCC N5 Adult, Development, and Cancer types 5.486E-3 3.497E-2
2.140E-1
1.000E0
 1 24
41 gudmap developingGonad e18.5 ovary 200 k3 DevelopingGonad e18.5 ovary emap-12283 k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 5.942E-3 3.695E-2
2.262E-1
1.000E0
 1 26
42 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup7/Nxph3 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup7/Nxph3 BrainMap 6.398E-3 3.794E-2
2.322E-1
1.000E0
 1 28
43 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-D/Kidney Normal Wilms EN-D/Kidney Normal Wilms EN22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-D/Kidney Normal Wilms EN-D/Kidney Normal Wilms EN22 Adult, Development, and Cancer types 6.398E-3 3.794E-2
2.322E-1
1.000E0
 1 28
44 Sample Type by Project: Shred 1/TCGA-Thryoid/Thyroid Papillary Carcinoma/Tall Cell/3/2 Sample Type by Project: Shred 1/TCGA-Thryoid/Thyroid Papillary Carcinoma/Tall Cell/3/2 TCGA-Thryoid 6.626E-3 3.840E-2
2.350E-1
1.000E0
 1 29
45 gudmap developingKidney e15.5 early proxim tubul 100 k3 DevelopingKidney e15.5 early proxim tubul emap-28005 k-means-cluster#3 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 7.537E-3 4.271E-2
2.614E-1
1.000E0
 1 33
46 gudmap developingGonad e16.5 epididymis 200 k1 DevelopingGonad e16.5 epididymis emap-29702 k-means-cluster#1 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 7.764E-3 4.304E-2
2.634E-1
1.000E0
 1 34
47 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Sfrp2 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Sfrp2 BrainMap 7.992E-3 4.336E-2
2.654E-1
1.000E0
 1 35
48 gudmap developingKidney e15.5 early proxim tubul 200 k5 DevelopingKidney e15.5 early proxim tubul emap-28005 k-means-cluster#5 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 9.129E-3 4.751E-2
2.908E-1
1.000E0
 1 40
49 gudmap developingGonad P2 epididymis 200 k3 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 9.129E-3 4.751E-2
2.908E-1
1.000E0
 1 40
50 gudmap developingKidney e15.5 Proximal Tubules 200 k5 DevelopingKidney e15.5 Proximal Tubules emap-28005 k-means-cluster#5 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 9.584E-3 4.888E-2
2.992E-1
1.000E0
 1 42
Show 45 more annotations

15: Computational [Display Chart] 3 input genes in category / 49 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M15921 MORF MT4 Neighborhood of MT4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.455E-5 7.129E-4 3.193E-3 7.129E-4 3 246
2 M16604 MORF PRKACA Neighborhood of PRKACA MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.610E-4 5.305E-3 2.376E-2 1.769E-2 2 111
3 M5177 MORF CASP10 Neighborhood of CASP10 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.011E-4 5.305E-3 2.376E-2 1.965E-2 2 117
4 M10328 MORF FLT1 Neighborhood of FLT1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.652E-4 5.305E-3 2.376E-2 2.280E-2 2 126
5 M5518 MORF RUNX1 Neighborhood of RUNX1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.591E-4 5.305E-3 2.376E-2 3.230E-2 2 150
6 M6373 MORF NF1 Neighborhood of NF1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 8.362E-4 5.305E-3 2.376E-2 4.097E-2 2 169
7 M5671 MORF STK17A Neighborhood of STK17A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 8.560E-4 5.305E-3 2.376E-2 4.195E-2 2 171
8 M11486 MORF ESR1 Neighborhood of ESR1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 8.661E-4 5.305E-3 2.376E-2 4.244E-2 2 172
9 M2795 MORF BNIP1 Neighborhood of BNIP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.056E-3 5.750E-3 2.576E-2
5.175E-2
 2 190
10 M19723 MORF BCL2 Neighborhood of BCL2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.440E-3 6.079E-3 2.723E-2
7.055E-2
 2 222
11 M2022 MORF TFDP2 Neighborhood of TFDP2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.545E-3 6.079E-3 2.723E-2
7.570E-2
 2 230
12 M3810 MORF IL13 Neighborhood of IL13 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.585E-3 6.079E-3 2.723E-2
7.767E-2
 2 233
13 M19290 MORF IL16 Neighborhood of IL16 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.695E-3 6.079E-3 2.723E-2
8.307E-2
 2 241
14 M10529 MORF MSH3 Neighborhood of MSH3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.737E-3 6.079E-3 2.723E-2
8.514E-2
 2 244
15 M1094 MORF BRCA1 Neighborhood of BRCA1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.032E-3 6.079E-3 2.723E-2
9.956E-2
 2 264
16 M18296 MORF TNFRSF25 Neighborhood of TNFRSF25 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.093E-3 6.079E-3 2.723E-2
1.026E-1
 2 268
17 M18287 MORF PAX7 Neighborhood of PAX7 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.109E-3 6.079E-3 2.723E-2
1.033E-1
 2 269
18 M8621 MORF NOS2A Neighborhood of NOS2A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.465E-3 6.710E-3 3.006E-2
1.208E-1
 2 291
19 M4363 MORF ARL3 Neighborhood of ARL3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.741E-3 7.069E-3 3.166E-2
1.343E-1
 2 307
20 M6407 MORF FOSL1 Neighborhood of FOSL1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.835E-3 1.185E-2
5.306E-2
2.369E-1
 2 409
21 M3103 MORF MAGEA9 Neighborhood of MAGEA9 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.264E-3 1.228E-2
5.502E-2
2.580E-1
 2 427
22 M11630 MODULE 404 Steroid hormone receptors and binding proteins. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.752E-3 1.727E-2
7.734E-2
3.798E-1
 1 26
23 M14346 MORF ETV3 Neighborhood of ETV3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.901E-2 4.050E-2
1.814E-1
9.315E-1
 1 64
24 M1890 MORF MYL3 Neighborhood of MYL3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.107E-2 4.303E-2
1.927E-1
1.000E0
 1 71
25 M17328 MORF MYC Neighborhood of MYC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.343E-2 4.592E-2
2.057E-1
1.000E0
 1 79
Show 20 more annotations

16: MicroRNA [Display Chart] 5 input genes in category / 242 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-302e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.790E-4 9.878E-3
5.994E-2
9.172E-2
 2 448
2 hsa-miR-520d-3p:Functional MTI Functional MTI miRTarbase 3.807E-4 9.878E-3
5.994E-2
9.213E-2
 2 449
3 hsa-miR-520e:Functional MTI Functional MTI miRTarbase 3.875E-4 9.878E-3
5.994E-2
9.377E-2
 2 453
4 hsa-miR-520b:Functional MTI Functional MTI miRTarbase 3.909E-4 9.878E-3
5.994E-2
9.459E-2
 2 455
5 hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 3.909E-4 9.878E-3
5.994E-2
9.459E-2
 2 455
6 hsa-miR-520c-3p:Functional MTI Functional MTI miRTarbase 3.909E-4 9.878E-3
5.994E-2
9.459E-2
 2 455
7 hsa-miR-302d-3p:Functional MTI Functional MTI miRTarbase 3.995E-4 9.878E-3
5.994E-2
9.667E-2
 2 460
8 hsa-miR-302b-3p:Functional MTI Functional MTI miRTarbase 3.995E-4 9.878E-3
5.994E-2
9.667E-2
 2 460
9 hsa-miR-372-3p:Non-Functional MTI Non-Functional MTI miRTarbase 4.012E-4 9.878E-3
5.994E-2
9.709E-2
 2 461
10 hsa-miR-302a-3p:Functional MTI Functional MTI miRTarbase 4.082E-4 9.878E-3
5.994E-2
9.878E-2
 2 465
11 hsa-miR-6726-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.038E-3 2.283E-2
1.385E-1
2.511E-1
 1 15
12 hsa-miR-659-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.798E-3 3.112E-2
1.888E-1
4.352E-1
 1 26
13 hsa-miR-2909:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.973E-3 3.112E-2
1.888E-1
7.194E-1
 1 43
14 hsa-miR-3126-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.111E-3 3.112E-2
1.888E-1
7.528E-1
 1 45
15 hsa-miR-6793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 3.112E-2
1.888E-1
8.196E-1
 1 49
16 hsa-miR-3157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.732E-3 3.112E-2
1.888E-1
9.031E-1
 1 54
17 hsa-miR-3914:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.870E-3 3.112E-2
1.888E-1
9.365E-1
 1 56
18 hsa-miR-26b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.870E-3 3.112E-2
1.888E-1
9.365E-1
 1 56
19 hsa-miR-6759-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.870E-3 3.112E-2
1.888E-1
9.365E-1
 1 56
20 hsa-miR-581:Functional MTI Functional MTI miRTarbase 3.939E-3 3.112E-2
1.888E-1
9.532E-1
 1 57
21 hsa-miR-1910-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 3.112E-2
1.888E-1
9.866E-1
 1 59
22 hsa-miR-4312:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 3.112E-2
1.888E-1
1.000E0
 1 63
23 hsa-miR-8065:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.422E-3 3.112E-2
1.888E-1
1.000E0
 1 64
24 hsa-miR-4797-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.698E-3 3.112E-2
1.888E-1
1.000E0
 1 68
25 hsa-miR-7852-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.836E-3 3.112E-2
1.888E-1
1.000E0
 1 70
26 hsa-miR-3668:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.836E-3 3.112E-2
1.888E-1
1.000E0
 1 70
27 AAGGGAT,MIR-188:MSigDB AAGGGAT,MIR-188:MSigDB MSigDB 4.905E-3 3.112E-2
1.888E-1
1.000E0
 1 71
28 hsa-miR-554:PITA hsa-miR-554:PITA TOP PITA 4.905E-3 3.112E-2
1.888E-1
1.000E0
 1 71
29 hsa-miR-203a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 3.112E-2
1.888E-1
1.000E0
 1 74
30 hsa-miR-125b-1*:mirSVR highEffct hsa-miR-125b-1*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.111E-3 3.112E-2
1.888E-1
1.000E0
 1 74
31 hsa-miR-874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.318E-3 3.112E-2
1.888E-1
1.000E0
 1 77
32 hsa-miR-6757-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.525E-3 3.112E-2
1.888E-1
1.000E0
 1 80
33 hsa-miR-7855-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.214E-3 3.112E-2
1.888E-1
1.000E0
 1 90
34 hsa-miR-2052:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.283E-3 3.112E-2
1.888E-1
1.000E0
 1 91
35 hsa-miR-644a:Functional MTI Functional MTI miRTarbase 6.420E-3 3.112E-2
1.888E-1
1.000E0
 1 93
36 hsa-miR-3922-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.420E-3 3.112E-2
1.888E-1
1.000E0
 1 93
37 hsa-miR-4290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.489E-3 3.112E-2
1.888E-1
1.000E0
 1 94
38 hsa-miR-3911:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.558E-3 3.112E-2
1.888E-1
1.000E0
 1 95
39 hsa-miR-324-5p:PITA hsa-miR-324-5p:PITA TOP PITA 6.558E-3 3.112E-2
1.888E-1
1.000E0
 1 95
40 hsa-miR-6073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.558E-3 3.112E-2
1.888E-1
1.000E0
 1 95
41 hsa-miR-934:PITA hsa-miR-934:PITA TOP PITA 6.696E-3 3.112E-2
1.888E-1
1.000E0
 1 97
42 hsa-miR-4264:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.765E-3 3.112E-2
1.888E-1
1.000E0
 1 98
43 ATAGGAA,MIR-202:MSigDB ATAGGAA,MIR-202:MSigDB MSigDB 6.833E-3 3.112E-2
1.888E-1
1.000E0
 1 99
44 hsa-miR-140-5p:Functional MTI Functional MTI miRTarbase 6.971E-3 3.112E-2
1.888E-1
1.000E0
 1 101
45 hsa-miR-4671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.040E-3 3.112E-2
1.888E-1
1.000E0
 1 102
46 GCACCTT,MIR-18B:MSigDB GCACCTT,MIR-18B:MSigDB MSigDB 7.178E-3 3.112E-2
1.888E-1
1.000E0
 1 104
47 GCACCTT,MIR-18A:MSigDB GCACCTT,MIR-18A:MSigDB MSigDB 7.178E-3 3.112E-2
1.888E-1
1.000E0
 1 104
48 hsa-miR-122:PITA hsa-miR-122:PITA TOP PITA 7.246E-3 3.112E-2
1.888E-1
1.000E0
 1 105
49 hsa-miR-3176:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.315E-3 3.112E-2
1.888E-1
1.000E0
 1 106
50 hsa-miR-19b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.315E-3 3.112E-2
1.888E-1
1.000E0
 1 106
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 4698 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000000699 estrone sulfate Stitch 1.740E-11 8.177E-8 7.385E-7 8.177E-8 5 163
2 ctd:D012459 Salicylates CTD 3.421E-9 2.339E-6 2.113E-5 1.607E-5 3 17
3 ctd:C023888 beta-hexachlorocyclohexane CTD 5.469E-9 2.339E-6 2.113E-5 2.569E-5 4 133
4 CID011208678 SureCN3587271 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
5 CID000033473 CNP-amino Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
6 ctd:C497827 2,2-bis(3-chloro-4-hydroxyphenyl)propane CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
7 DB08020 (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL Drug Bank 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
8 ctd:C024871 16 alpha-iodoestradiol CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
9 CID000197608 butolame Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
10 CID010214678 CHEMBL397775 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
11 DB00481 Raloxifene Drug Bank 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
12 CID011174414 (4R)-4-(4-hydroxyphenyl)-6-methylol-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
13 CID011674420 CHEBI:428952 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
14 CID011688293 CHEBI:428946 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
15 ctd:C036101 tri-(2-ethylhexyl)trimellitate CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
16 ctd:C518540 Y134 compound CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
17 ctd:C113642 JK 1624F2-1 CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
18 CID016103245 Pyrazolo[1,5-a]pyrimidine, 12d Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
19 DB06927 [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE Drug Bank 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
20 DB04574 Estropipate Drug Bank 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
21 ctd:C100092 bromophos CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
22 ctd:C005704 salicylaldoxime CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
23 CID010215026 6-(4-hydroxyphenyl)-6,6a,7,8,9,10,11,11a-octahydrocyclohepta[c]chromen-2-ol Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
24 CID000160446 Brn 0187733 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
25 CID010192968 CHEMBL234633 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
26 ctd:C047437 indenestrol CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
27 CID011370317 Cyclohexanone, 3b Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
28 DB07638 (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL Drug Bank 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
29 ctd:C433164 tetrahydrodaidzein CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
30 ctd:C003140 phytofluene CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
31 CID011720174 SureCN1360427 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
32 CID010149292 SureCN14514737 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
33 CID011519653 SureCN3118249 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
34 ctd:D000272 Adipates CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
35 CID011197931 2z4b Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
36 ctd:C088673 octocrylene CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
37 ctd:C042791 di-(5-methylhexyl)phthalate CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
38 CID003517936 2-phenylbenzofuran Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
39 CID011522286 CHEMBL48352 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
40 ctd:C451418 ethyl cinnamate CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
41 CID010192967 SureCN14514707 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
42 CID011175195 (4R)-6-(ethoxymethyl)-4-(4-hydroxyphenyl)-1,2,3,3a,4,9b-hexahydrocyclopenta[c]chromen-8-ol Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
43 ctd:C020225 benzohydrol CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
44 DB07933 (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL Drug Bank 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
45 ctd:C113977 5-octylphenol CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
46 CID005327043 LY2066948 Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
47 CID000102225 dehydroestrone Stitch 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
48 ctd:C100185 phytoene CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
49 ctd:C478102 ERB 041 CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
50 ctd:C497826 2-(3-chloro-4-hydroxyphenyl)-2-(4-hydroxyphenyl)propane CTD 3.834E-8 2.339E-6 2.113E-5 1.801E-4 2 2
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 534 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1509148 Sclerosing hemangioma DisGeNET BeFree 2.285E-7 1.220E-4 8.368E-4 1.220E-4 2 3
2 C0947622 Cholecystolithiasis DisGeNET BeFree 5.842E-7 1.560E-4 1.070E-3 3.120E-4 3 64
3 C0028081 Night sweats DisGeNET Curated 1.142E-6 1.707E-4 1.171E-3 6.098E-4 2 6
4 C1720816 Endometrial Diseases DisGeNET BeFree 1.598E-6 1.707E-4 1.171E-3 8.536E-4 2 7
5 C0520676 Premenstrual Dysphoric Disorder DisGeNET BeFree 1.598E-6 1.707E-4 1.171E-3 8.536E-4 2 7
6 C0008350 Cholelithiasis DisGeNET Curated 2.851E-6 2.537E-4 1.740E-3 1.522E-3 3 108
7 C0236848 Age-related cognitive decline DisGeNET BeFree 5.021E-6 3.830E-4 2.627E-3 2.681E-3 2 12
8 C0349231 Phobic anxiety disorder DisGeNET Curated 6.921E-6 4.106E-4 2.816E-3 3.696E-3 2 14
9 C0027086 Myoma DisGeNET BeFree 6.921E-6 4.106E-4 2.816E-3 3.696E-3 2 14
10 C1854365 BREAST CANCER 3 DisGeNET Curated 9.124E-6 4.429E-4 3.038E-3 4.872E-3 2 16
11 C1705254 Neonatal Deformity DisGeNET BeFree 9.124E-6 4.429E-4 3.038E-3 4.872E-3 2 16
12 C0600142 Hot flushes DisGeNET BeFree 1.300E-5 5.339E-4 3.662E-3 6.940E-3 2 19
13 C0002991 Cutaneous Fibrous Histiocytoma DisGeNET BeFree 1.300E-5 5.339E-4 3.662E-3 6.940E-3 2 19
14 C0588008 Severe depression DisGeNET Curated 1.755E-5 6.474E-4 4.440E-3 9.372E-3 2 22
15 C0008370 Cholestasis DisGeNET Curated 1.819E-5 6.474E-4 4.440E-3 9.711E-3 3 200
16 C0346156 Benign neoplasm of breast DisGeNET BeFree 2.468E-5 8.237E-4 5.649E-3 1.318E-2 2 26
17 C0042344 Varicose Ulcer DisGeNET BeFree 2.870E-5 8.662E-4 5.941E-3 1.532E-2 2 28
18 C0497406 Overweight DisGeNET Curated 3.061E-5 8.662E-4 5.941E-3 1.635E-2 3 238
19 C0021361 Female infertility DisGeNET Curated 3.082E-5 8.662E-4 5.941E-3 1.646E-2 2 29
20 C1853195 Prostate Cancer, Hereditary, 7 DisGeNET Curated 3.764E-5 1.005E-3 6.892E-3 2.010E-2 2 32
21 C0017612 Glaucoma, Open-Angle DisGeNET Curated 4.778E-5 1.173E-3 8.043E-3 2.552E-2 2 36
22 C0263746 Osteoarthritis of the hand DisGeNET BeFree 5.051E-5 1.173E-3 8.043E-3 2.697E-2 2 37
23 C2267227 Bulimia Nervosa DisGeNET Curated 5.051E-5 1.173E-3 8.043E-3 2.697E-2 2 37
24 C0002893 Refractory anemias DisGeNET Curated 5.467E-5 1.200E-3 8.230E-3 2.919E-2 3 289
25 C1280433 Lipoatrophy DisGeNET Curated 5.618E-5 1.200E-3 8.230E-3 3.000E-2 2 39
26 C3669246 Mammary adenocarcinoma DisGeNET BeFree 7.168E-5 1.472E-3 1.010E-2 3.828E-2 2 44
27 C0023892 Biliary cirrhosis DisGeNET Curated 8.188E-5 1.562E-3 1.071E-2 4.372E-2 2 47
28 C0029458 Osteoporosis, Postmenopausal DisGeNET Curated 8.188E-5 1.562E-3 1.071E-2 4.372E-2 2 47
29 C0848558 Hypospadias DisGeNET Curated 8.905E-5 1.640E-3 1.125E-2 4.755E-2 2 49
30 C0007104 Female Breast Carcinoma DisGeNET BeFree 9.275E-5 1.651E-3 1.132E-2 4.953E-2 2 50
31 C0238033 Carcinoma of Male Breast DisGeNET BeFree 1.207E-4 2.080E-3 1.426E-2
6.447E-2
 2 57
32 C0206650 Fibroadenoma DisGeNET Curated 1.250E-4 2.086E-3 1.431E-2
6.677E-2
 2 58
33 C0740277 Bile duct carcinoma DisGeNET Curated 1.294E-4 2.094E-3 1.436E-2
6.910E-2
 2 59
34 C0010701 Phyllodes Tumor DisGeNET Curated 1.384E-4 2.173E-3 1.491E-2
7.389E-2
 2 61
35 C0154723 Migraine with Aura DisGeNET Curated 1.721E-4 2.626E-3 1.801E-2
9.190E-2
 2 68
36 C0014173 Endometrial Hyperplasia DisGeNET Curated 1.984E-4 2.943E-3 2.019E-2
1.060E-1
 2 73
37 C0016034 Breast Fibrocystic Disease DisGeNET BeFree 2.151E-4 3.023E-3 2.073E-2
1.149E-1
 2 76
38 C2986665 Early-Stage Breast Carcinoma DisGeNET BeFree 2.151E-4 3.023E-3 2.073E-2
1.149E-1
 2 76
39 C0039585 Androgen-Insensitivity Syndrome DisGeNET Curated 2.324E-4 3.051E-3 2.093E-2
1.241E-1
 2 79
40 C0003125 Anorexia Nervosa DisGeNET Curated 2.444E-4 3.051E-3 2.093E-2
1.305E-1
 2 81
41 C0278704 Malignant Childhood Neoplasm DisGeNET BeFree 2.505E-4 3.051E-3 2.093E-2
1.337E-1
 2 82
42 C0269102 Endometrioma DisGeNET BeFree 2.628E-4 3.051E-3 2.093E-2
1.404E-1
 2 84
43 C0014170 Endometrial Neoplasms DisGeNET Curated 2.628E-4 3.051E-3 2.093E-2
1.404E-1
 2 84
44 C1527349 Ductal Breast Carcinoma DisGeNET BeFree 2.951E-4 3.051E-3 2.093E-2
1.576E-1
 2 89
45 C1335184 Ovarian Transitional Cell Carcinoma DisGeNET BeFree 3.085E-4 3.051E-3 2.093E-2
1.648E-1
 1 1
46 C0017577 Gingivosis DisGeNET BeFree 3.085E-4 3.051E-3 2.093E-2
1.648E-1
 1 1
47 C0015799 Feminization DisGeNET Curated 3.085E-4 3.051E-3 2.093E-2
1.648E-1
 1 1
48 C0549618 MALE GENITAL ABNORMALITIES DisGeNET BeFree 3.085E-4 3.051E-3 2.093E-2
1.648E-1
 1 1
49 C0149870 De Quervain Disease DisGeNET BeFree 3.085E-4 3.051E-3 2.093E-2
1.648E-1
 1 1
50 C4021240 Elevated tissue non-specific alkaline phosphatase DisGeNET Curated 3.085E-4 3.051E-3 2.093E-2
1.648E-1
 1 1
Show 45 more annotations