Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc182_12, positive side

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1: GO: Molecular Function [Display Chart] 12 input genes in category / 23 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001077 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific 5.813E-9 1.337E-7 4.993E-7 1.337E-7 6 259
2 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 3.942E-8 3.448E-7 1.287E-6 9.067E-7 6 357
3 GO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding 4.497E-8 3.448E-7 1.287E-6 1.034E-6 6 365
4 GO:0001046 core promoter sequence-specific DNA binding 6.521E-7 3.750E-6 1.400E-5 1.500E-5 4 115
5 GO:0001047 core promoter binding 2.695E-6 1.239E-5 4.629E-5 6.197E-5 4 164
6 GO:0001158 enhancer sequence-specific DNA binding 2.552E-5 9.649E-5 3.603E-4 5.869E-4 3 93
7 GO:0003713 transcription coactivator activity 3.328E-5 9.649E-5 3.603E-4 7.655E-4 4 310
8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding 3.567E-5 9.649E-5 3.603E-4 8.204E-4 3 104
9 GO:0035326 enhancer binding 3.776E-5 9.649E-5 3.603E-4 8.684E-4 3 106
10 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 7.947E-4 1.828E-3 6.826E-3 1.828E-2 2 66
11 GO:0097157 pre-mRNA intronic binding 5.134E-3 1.073E-2 4.009E-2
1.181E-1
 1 8
12 GO:0034236 protein kinase A catalytic subunit binding 9.606E-3 1.841E-2
6.875E-2
2.209E-1
 1 15
13 GO:0035198 miRNA binding 1.088E-2 1.925E-2
7.189E-2
2.503E-1
 1 17
14 GO:0036002 pre-mRNA binding 1.596E-2 2.623E-2
9.793E-2
3.672E-1
 1 25
15 GO:0043425 bHLH transcription factor binding 1.913E-2 2.933E-2
1.095E-1
4.399E-1
 1 30
16 GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding 2.373E-2 3.412E-2
1.274E-1
5.459E-1
 2 379
17 GO:0000987 proximal promoter sequence-specific DNA binding 2.600E-2 3.518E-2
1.314E-1
5.980E-1
 2 398
18 GO:0051018 protein kinase A binding 2.982E-2 3.810E-2
1.423E-1
6.858E-1
 1 47
Show 13 more annotations

2: GO: Biological Process [Display Chart] 12 input genes in category / 716 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0048863 stem cell differentiation 2.096E-12 1.500E-9 1.073E-8 1.500E-9 8 303
2 GO:0010001 glial cell differentiation 1.584E-11 5.670E-9 4.055E-8 1.134E-8 7 210
3 GO:0042063 gliogenesis 1.167E-10 2.786E-8 1.993E-7 8.359E-8 7 279
4 GO:0072089 stem cell proliferation 4.354E-10 7.793E-8 5.573E-7 3.117E-7 6 168
5 GO:2000741 positive regulation of mesenchymal stem cell differentiation 8.173E-10 1.170E-7 8.370E-7 5.852E-7 3 4
6 GO:0048709 oligodendrocyte differentiation 2.266E-9 2.704E-7 1.934E-6 1.622E-6 5 94
7 GO:2000739 regulation of mesenchymal stem cell differentiation 4.084E-9 4.177E-7 2.987E-6 2.924E-6 3 6
8 GO:0072091 regulation of stem cell proliferation 5.263E-9 4.710E-7 3.368E-6 3.768E-6 5 111
9 GO:0045165 cell fate commitment 8.241E-9 6.556E-7 4.688E-6 5.900E-6 6 274
10 GO:0072497 mesenchymal stem cell differentiation 1.143E-8 8.181E-7 5.851E-6 8.181E-6 3 8
11 GO:0060174 limb bud formation 2.447E-8 1.593E-6 1.139E-5 1.752E-5 3 10
12 GO:0021781 glial cell fate commitment 9.260E-8 5.367E-6 3.838E-5 6.630E-5 3 15
13 GO:0035239 tube morphogenesis 9.744E-8 5.367E-6 3.838E-5 6.977E-5 6 415
14 GO:2000648 positive regulation of stem cell proliferation 1.304E-7 6.668E-6 4.769E-5 9.336E-5 4 77
15 GO:0001708 cell fate specification 2.343E-7 1.118E-5 7.997E-5 1.677E-4 4 89
16 GO:0032332 positive regulation of chondrocyte differentiation 2.701E-7 1.209E-5 8.644E-5 1.934E-4 3 21
17 GO:0050768 negative regulation of neurogenesis 5.879E-7 2.476E-5 1.771E-4 4.209E-4 5 285
18 GO:0051961 negative regulation of nervous system development 8.765E-7 3.427E-5 2.451E-4 6.276E-4 5 309
19 GO:0061036 positive regulation of cartilage development 9.095E-7 3.427E-5 2.451E-4 6.512E-4 3 31
20 GO:0035270 endocrine system development 1.573E-6 5.631E-5 4.027E-4 1.126E-3 4 143
21 GO:0010721 negative regulation of cell development 1.712E-6 5.838E-5 4.175E-4 1.226E-3 5 354
22 GO:0060562 epithelial tube morphogenesis 2.214E-6 7.205E-5 5.153E-4 1.585E-3 5 373
23 GO:0048483 autonomic nervous system development 2.857E-6 8.893E-5 6.360E-4 2.045E-3 3 45
24 GO:0032330 regulation of chondrocyte differentiation 3.704E-6 1.105E-4 7.902E-4 2.652E-3 3 49
25 GO:2000738 positive regulation of stem cell differentiation 4.977E-6 1.425E-4 1.019E-3 3.564E-3 3 54
26 GO:0007405 neuroblast proliferation 7.203E-6 1.984E-4 1.419E-3 5.158E-3 3 61
27 GO:0003357 noradrenergic neuron differentiation 7.979E-6 2.116E-4 1.513E-3 5.713E-3 2 7
28 GO:0061035 regulation of cartilage development 9.142E-6 2.257E-4 1.614E-3 6.546E-3 3 66
29 GO:0060425 lung morphogenesis 9.142E-6 2.257E-4 1.614E-3 6.546E-3 3 66
30 GO:0045665 negative regulation of neuron differentiation 9.856E-6 2.352E-4 1.682E-3 7.057E-3 4 227
31 GO:0071560 cellular response to transforming growth factor beta stimulus 1.038E-5 2.370E-4 1.695E-3 7.432E-3 4 230
32 GO:0032808 lacrimal gland development 1.063E-5 2.370E-4 1.695E-3 7.614E-3 2 8
33 GO:0071559 response to transforming growth factor beta 1.092E-5 2.370E-4 1.695E-3 7.822E-3 4 233
34 GO:0060828 regulation of canonical Wnt signaling pathway 1.310E-5 2.760E-4 1.974E-3 9.383E-3 4 244
35 GO:0014032 neural crest cell development 1.399E-5 2.863E-4 2.047E-3 1.002E-2 3 76
36 GO:0035019 somatic stem cell population maintenance 1.456E-5 2.879E-4 2.059E-3 1.042E-2 3 77
37 GO:0003007 heart morphogenesis 1.488E-5 2.879E-4 2.059E-3 1.065E-2 4 252
38 GO:0003211 cardiac ventricle formation 1.708E-5 3.218E-4 2.301E-3 1.223E-2 2 10
39 GO:0014033 neural crest cell differentiation 1.891E-5 3.472E-4 2.483E-3 1.354E-2 3 84
40 GO:0060563 neuroepithelial cell differentiation 2.327E-5 4.165E-4 2.979E-3 1.666E-2 3 90
41 GO:0003207 cardiac chamber formation 2.503E-5 4.371E-4 3.126E-3 1.792E-2 2 12
42 GO:0022405 hair cycle process 3.096E-5 5.039E-4 3.603E-3 2.217E-2 3 99
43 GO:0022404 molting cycle process 3.096E-5 5.039E-4 3.603E-3 2.217E-2 3 99
44 GO:0001942 hair follicle development 3.096E-5 5.039E-4 3.603E-3 2.217E-2 3 99
45 GO:0060070 canonical Wnt signaling pathway 3.271E-5 5.117E-4 3.659E-3 2.342E-2 4 308
46 GO:0098773 skin epidermis development 3.287E-5 5.117E-4 3.659E-3 2.354E-2 3 101
47 GO:0002062 chondrocyte differentiation 3.693E-5 5.625E-4 4.023E-3 2.644E-2 3 105
48 GO:0030111 regulation of Wnt signaling pathway 3.892E-5 5.805E-4 4.152E-3 2.786E-2 4 322
49 GO:0048562 embryonic organ morphogenesis 4.084E-5 5.968E-4 4.268E-3 2.924E-2 4 326
50 GO:0021510 spinal cord development 4.478E-5 6.413E-4 4.586E-3 3.206E-2 3 112
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 12 input genes in category / 12 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0044798 nuclear transcription factor complex 1.213E-8 1.455E-7 4.516E-7 1.455E-7 5 134
2 GO:0005667 transcription factor complex 4.166E-8 2.499E-7 7.756E-7 4.999E-7 6 368
3 GO:0031315 extrinsic component of mitochondrial outer membrane 3.144E-3 1.258E-2 3.903E-2 3.773E-2 1 5

4: Human Phenotype [Display Chart] 7 input genes in category / 888 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0000044 Hypogonadotrophic hypogonadism 8.704E-6 2.515E-3 1.853E-2 7.729E-3 4 108
2 HP:0001335 Bimanual synkinesia 9.811E-6 2.515E-3 1.853E-2 8.712E-3 3 32
3 HP:0100842 Septo-optic dysplasia 1.078E-5 2.515E-3 1.853E-2 9.577E-3 3 33
4 HP:0000026 Male hypogonadism 1.409E-5 2.515E-3 1.853E-2 1.251E-2 3 36
5 HP:0004408 Abnormality of the sense of smell 1.416E-5 2.515E-3 1.853E-2 1.258E-2 4 122
6 HP:0011757 Posterior pituitary hypoplasia 5.286E-5 7.824E-3
5.764E-2
 4.694E-2 2 8
7 HP:0003316 Butterfly vertebrae 1.243E-4 1.177E-2
8.669E-2
1.103E-1
 2 12
8 HP:0001331 Absent septum pellucidum 1.299E-4 1.177E-2
8.669E-2
1.154E-1
 3 75
9 HP:0000609 Optic nerve hypoplasia 1.299E-4 1.177E-2
8.669E-2
1.154E-1
 3 75
10 HP:0000326 Abnormality of the maxilla 1.455E-4 1.177E-2
8.669E-2
1.292E-1
 4 220
11 HP:0000966 Hypohidrosis 1.888E-4 1.177E-2
8.669E-2
1.677E-1
 3 85
12 HP:0000838 Abnormality of the pituitary gland 2.010E-4 1.177E-2
8.669E-2
1.785E-1
 4 239
13 HP:0000844 Growth hormone and pituitary abnormality 2.010E-4 1.177E-2
8.669E-2
1.785E-1
 4 239
14 HP:0007375 Abnormality of the septum pellucidum 2.024E-4 1.177E-2
8.669E-2
1.797E-1
 3 87
15 HP:0011748 Adrenocorticotropic hormone deficiency 2.253E-4 1.177E-2
8.669E-2
2.000E-1
 2 16
16 HP:0011753 Posterior pituitary dysgenesis 2.253E-4 1.177E-2
8.669E-2
2.000E-1
 2 16
17 HP:0011755 Ectopic posterior pituitary 2.253E-4 1.177E-2
8.669E-2
2.000E-1
 2 16
18 HP:0012245 Sex reversal 2.551E-4 1.230E-2
9.064E-2
2.266E-1
 2 17
19 HP:0001093 Optic nerve dysplasia 2.868E-4 1.230E-2
9.064E-2
2.547E-1
 2 18
20 HP:0010636 Schizencephaly 2.868E-4 1.230E-2
9.064E-2
2.547E-1
 2 18
21 HP:0010650 Hypoplasia of the premaxilla 3.153E-4 1.230E-2
9.064E-2
2.800E-1
 3 101
22 HP:0010756 Aplasia/Hypoplasia of the premaxilla 3.153E-4 1.230E-2
9.064E-2
2.800E-1
 3 101
23 HP:0010627 Anterior pituitary hypoplasia 3.203E-4 1.230E-2
9.064E-2
2.845E-1
 2 19
24 HP:0000458 Anosmia 3.439E-4 1.230E-2
9.064E-2
3.054E-1
 3 104
25 HP:0007807 Optic nerve compression 3.557E-4 1.230E-2
9.064E-2
3.158E-1
 2 20
26 HP:0000457 Depressed nasal ridge 3.741E-4 1.230E-2
9.064E-2
3.322E-1
 3 107
27 HP:0010758 Abnormality of the premaxilla 3.741E-4 1.230E-2
9.064E-2
3.322E-1
 3 107
28 HP:0010625 Anterior pituitary dysgenesis 3.928E-4 1.237E-2
9.109E-2
3.488E-1
 2 21
29 HP:0007036 Hypoplasia of olfactory tract 4.318E-4 1.237E-2
9.109E-2
3.835E-1
 2 22
30 HP:0000878 11 pairs of ribs 4.318E-4 1.237E-2
9.109E-2
3.835E-1
 2 22
31 HP:0011747 Abnormality of the anterior pituitary 4.550E-4 1.237E-2
9.109E-2
4.041E-1
 4 295
32 HP:0008515 Aplasia/Hypoplasia of the vertebrae 4.726E-4 1.237E-2
9.109E-2
4.197E-1
 2 23
33 HP:0008417 Vertebral hypoplasia 4.726E-4 1.237E-2
9.109E-2
4.197E-1
 2 23
34 HP:0012503 Abnormality of the pituitary gland 5.110E-4 1.237E-2
9.109E-2
4.538E-1
 4 304
35 HP:0012244 Abnormal sex determination 5.152E-4 1.237E-2
9.109E-2
4.575E-1
 2 24
36 HP:0008428 Vertebral clefting 5.152E-4 1.237E-2
9.109E-2
4.575E-1
 2 24
37 HP:0000871 Panhypopituitarism 5.152E-4 1.237E-2
9.109E-2
4.575E-1
 2 24
38 HP:0001293 Cranial nerve compression 5.596E-4 1.308E-2
9.634E-2
4.969E-1
 2 25
39 HP:0100667 Brachydactyly (hand) 6.152E-4 1.401E-2
1.032E-1
5.463E-1
 4 319
40 HP:0002281 Gray matter heterotopias 6.538E-4 1.451E-2
1.069E-1
5.806E-1
 2 27
41 HP:0007766 Optic disc hypoplasia 7.036E-4 1.524E-2
1.123E-1
6.248E-1
 2 28
42 HP:0003189 Long nose 7.552E-4 1.597E-2
1.176E-1
6.706E-1
 2 29
43 HP:0000864 Abnormality of the hypothalamus-pituitary axis 7.948E-4 1.632E-2
1.202E-1
7.058E-1
 4 341
44 HP:0010459 True hermaphroditism 8.086E-4 1.632E-2
1.202E-1
7.180E-1
 2 30
45 HP:0011751 Abnormality of the posterior pituitary 8.637E-4 1.704E-2
1.256E-1
7.670E-1
 2 31
46 HP:0008736 Hypoplasia of penis 9.272E-4 1.790E-2
1.319E-1
8.234E-1
 4 355
47 HP:0003468 Abnormal vertebral morphology 9.474E-4 1.790E-2
1.319E-1
8.413E-1
 4 357
48 HP:0000135 Hypogonadism 9.678E-4 1.790E-2
1.319E-1
8.594E-1
 4 359
49 HP:0002778 Abnormal trachea morphology 1.011E-3 1.831E-2
1.349E-1
8.973E-1
 3 150
50 HP:0000921 Missing ribs 1.040E-3 1.847E-2
1.360E-1
9.234E-1
 2 34
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 12 input genes in category / 969 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0002898 absent cartilage 2.374E-8 2.204E-5 1.643E-4 2.300E-5 3 6
2 MP:0002896 abnormal bone mineralization 4.549E-8 2.204E-5 1.643E-4 4.408E-5 6 204
3 MP:0000157 abnormal sternum morphology 8.159E-8 2.635E-5 1.964E-4 7.906E-5 6 225
4 MP:0011261 abnormal limb mesenchyme morphology 2.601E-7 5.911E-5 4.406E-4 2.520E-4 3 12
5 MP:0004508 abnormal pectoral girdle bone morphology 3.050E-7 5.911E-5 4.406E-4 2.956E-4 6 281
6 MP:0030572 abnormal pilosebaceous unit morphology 4.315E-7 6.969E-5 5.194E-4 4.181E-4 6 298
7 MP:0004322 abnormal sternebra morphology 5.564E-7 7.702E-5 5.741E-4 5.391E-4 4 62
8 MP:0001025 abnormal sympathetic neuron morphology 8.013E-7 8.627E-5 6.431E-4 7.765E-4 3 17
9 MP:0006221 optic nerve hypoplasia 8.013E-7 8.627E-5 6.431E-4 7.765E-4 3 17
10 MP:0000287 heart valve hypoplasia 1.231E-6 1.193E-4 8.893E-4 1.193E-3 2 2
11 MP:0010082 sternebra fusion 1.563E-6 1.377E-4 1.026E-3 1.515E-3 3 21
12 MP:0001270 distended abdomen 3.111E-6 2.476E-4 1.846E-3 3.014E-3 4 95
13 MP:0020342 small optic nerve 3.424E-6 2.476E-4 1.846E-3 3.318E-3 3 27
14 MP:0004624 abnormal thoracic cage morphology 3.599E-6 2.476E-4 1.846E-3 3.488E-3 6 428
15 MP:0002657 chondrodystrophy 3.833E-6 2.476E-4 1.846E-3 3.714E-3 3 28
16 MP:0008271 abnormal bone ossification 4.633E-6 2.806E-4 2.091E-3 4.489E-3 6 447
17 MP:0009450 abnormal axon fasciculation 5.788E-6 3.299E-4 2.459E-3 5.608E-3 3 32
18 MP:0005650 abnormal limb bud morphology 6.906E-6 3.517E-4 2.622E-3 6.692E-3 4 116
19 MP:0008510 absent retinal ganglion layer 7.377E-6 3.517E-4 2.622E-3 7.149E-3 2 4
20 MP:0013342 bifurcated Rathke's pouch 7.377E-6 3.517E-4 2.622E-3 7.149E-3 2 4
21 MP:0012076 abnormal agouti pigmentation 7.622E-6 3.517E-4 2.622E-3 7.386E-3 3 35
22 MP:0008068 absent retinal ganglion cell 1.229E-5 5.412E-4 4.034E-3 1.191E-2 2 5
23 MP:0004321 short sternum 1.430E-5 6.024E-4 4.490E-3 1.385E-2 3 43
24 MP:0030878 abnormal fibrous joint morphology 1.766E-5 7.132E-4 5.316E-3 1.712E-2 4 147
25 MP:0008514 absent retinal inner plexiform layer 1.842E-5 7.140E-4 5.322E-3 1.785E-2 2 6
26 MP:0011260 abnormal head mesenchyme morphology 1.997E-5 7.444E-4 5.549E-3 1.935E-2 3 48
27 MP:0011099 lethality throughout fetal growth and development, complete penetrance 2.131E-5 7.649E-4 5.702E-3 2.065E-2 5 331
28 MP:0003755 abnormal palate morphology 2.427E-5 8.398E-4 6.260E-3 2.351E-2 5 340
29 MP:0004323 sternum hypoplasia 2.577E-5 8.611E-4 6.419E-3 2.497E-2 2 7
30 MP:0006126 abnormal cardiac outflow tract development 3.060E-5 9.507E-4 7.087E-3 2.965E-2 4 169
31 MP:0001951 abnormal breathing pattern 3.155E-5 9.507E-4 7.087E-3 3.057E-2 5 359
32 MP:0006279 abnormal limb development 3.355E-5 9.507E-4 7.087E-3 3.251E-2 4 173
33 MP:0001011 abnormal superior cervical ganglion morphology 3.359E-5 9.507E-4 7.087E-3 3.255E-2 3 57
34 MP:0001017 abnormal stellate ganglion morphology 3.434E-5 9.507E-4 7.087E-3 3.328E-2 2 8
35 MP:0012744 increased neural crest cell apoptosis 3.434E-5 9.507E-4 7.087E-3 3.328E-2 2 8
36 MP:0000159 abnormal xiphoid process morphology 4.121E-5 1.109E-3 8.268E-3 3.993E-2 3 61
37 MP:0008317 abnormal paravertebral ganglion morphology 4.328E-5 1.133E-3 8.448E-3 4.193E-2 3 62
38 MP:0003400 kinked neural tube 4.541E-5 1.158E-3 8.631E-3 4.400E-2 3 63
39 MP:0003115 abnormal respiratory system development 4.945E-5 1.229E-3 9.159E-3 4.792E-2 4 191
40 MP:0001008 abnormal sympathetic ganglion morphology 5.464E-5 1.242E-3 9.258E-3
5.294E-2
 3 67
41 MP:0011262 abnormal pharyngeal arch mesenchyme morphology 5.512E-5 1.242E-3 9.258E-3
5.341E-2
 2 10
42 MP:0009284 abnormal sympathetic neuron innervation pattern 5.512E-5 1.242E-3 9.258E-3
5.341E-2
 2 10
43 MP:0010395 abnormal pharyngeal arch development 5.512E-5 1.242E-3 9.258E-3
5.341E-2
 2 10
44 MP:0000163 abnormal cartilage morphology 5.973E-5 1.315E-3 9.805E-3
5.788E-2
 5 410
45 MP:0002187 abnormal fibula morphology 6.502E-5 1.400E-3 1.044E-2
6.300E-2
 3 71
46 MP:0002327 abnormal respiratory function 7.173E-5 1.511E-3 1.126E-2
6.950E-2
 5 426
47 MP:0002111 abnormal tail morphology 7.584E-5 1.564E-3 1.165E-2
7.348E-2
 5 431
48 MP:0003935 abnormal craniofacial development 7.753E-5 1.565E-3 1.167E-2
7.513E-2
 5 433
49 MP:0012176 abnormal head development 7.971E-5 1.576E-3 1.175E-2
7.724E-2
 3 76
50 MP:0001007 abnormal sympathetic system morphology 8.614E-5 1.669E-3 1.244E-2
8.347E-2
 3 78
Show 45 more annotations

6: Domain [Display Chart] 12 input genes in category / 21 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF00505 HMG box Pfam 6.858E-32 5.921E-31 2.158E-30 1.440E-30 12 53
2 SM00398 HMG SMART 8.817E-32 5.921E-31 2.158E-30 1.852E-30 12 54
3 PS50118 HMG BOX 2 PROSITE 8.817E-32 5.921E-31 2.158E-30 1.852E-30 12 54
4 1.10.30.10 - Gene3D 1.128E-31 5.921E-31 2.158E-30 2.368E-30 12 55
5 IPR009071 HMG box dom InterPro 1.035E-30 4.349E-30 1.585E-29 2.174E-29 12 65
6 PF12336 SOXp Pfam 2.006E-9 6.019E-9 2.194E-8 4.213E-8 3 5
7 IPR022097 SOX fam InterPro 2.006E-9 6.019E-9 2.194E-8 4.213E-8 3 5
8 PF12444 Sox N Pfam 1.128E-6 2.632E-6 9.593E-6 2.369E-5 2 3
9 IPR022151 Sox N InterPro 1.128E-6 2.632E-6 9.593E-6 2.369E-5 2 3
10 IPR010978 tRNA-bd arm InterPro 1.030E-4 2.163E-4 7.884E-4 2.163E-3 2 24
11 IPR029551 SOX-11 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
12 IPR027153 SOX-6 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
13 IPR029548 SOX-9 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
14 IPR029550 SOX-3 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
15 IPR031267 SOX-12 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
16 IPR029547 SOX-13 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
17 IPR032643 SOX-2 InterPro 6.405E-4 7.912E-4 2.884E-3 1.345E-2 1 1
18 IPR021934 Sox C InterPro 1.920E-3 1.920E-3 7.001E-3 4.033E-2 1 3
19 IPR033392 Sox7/17/18 central InterPro 1.920E-3 1.920E-3 7.001E-3 4.033E-2 1 3
20 PF12067 Sox17 18 mid Pfam 1.920E-3 1.920E-3 7.001E-3 4.033E-2 1 3
21 PS51516 SOX C PROSITE 1.920E-3 1.920E-3 7.001E-3 4.033E-2 1 3
Show 16 more annotations

7: Pathway [Display Chart] 6 input genes in category / 11 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269604 Deactivation of the beta-catenin transactivating complex BioSystems: REACTOME 1.180E-15 1.298E-14 3.920E-14 1.298E-14 6 43
2 1269599 TCF dependent signaling in response to WNT BioSystems: REACTOME 5.073E-11 2.790E-10 8.426E-10 5.580E-10 6 242
3 1269594 Signaling by Wnt BioSystems: REACTOME 3.973E-10 1.457E-9 4.399E-9 4.370E-9 6 340
4 1270348 POU5F1 (OCT4), SOX2, NANOG repress genes related to differentiation BioSystems: REACTOME 1.445E-3 3.974E-3 1.200E-2 1.590E-2 1 3
5 1270347 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation BioSystems: REACTOME 6.250E-3 1.375E-2 4.152E-2
6.875E-2
 1 13
6 1270346 Transcriptional regulation of pluripotent stem cells BioSystems: REACTOME 1.723E-2 3.158E-2
9.538E-2
1.895E-1
 1 36
Show 1 more annotation

8: Pubmed [Display Chart] 12 input genes in category / 4403 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 27241892 Spatio-temporal expression of Sox genes in murine palatogenesis. Pubmed 3.082E-43 6.785E-40 6.084E-39 1.357E-39 12 17
2 26864488 Expression of Sox genes in tooth development. Pubmed 3.082E-43 6.785E-40 6.084E-39 1.357E-39 12 17
3 8921394 Numerous members of the Sox family of HMG box-containing genes are expressed in developing mouse teeth. Pubmed 3.634E-35 5.333E-32 4.782E-31 1.600E-31 10 14
4 12815626 Expression of Sox transcription factors in the developing mouse pancreas. Pubmed 1.588E-33 1.748E-30 1.568E-29 6.992E-30 10 18
5 10037800 From head to toes: the multiple facets of Sox proteins. Pubmed 4.621E-33 4.069E-30 3.649E-29 2.035E-29 9 10
6 8441686 Seven new members of the Sox gene family expressed during mouse development. Pubmed 3.303E-31 2.424E-28 2.174E-27 1.454E-27 9 13
7 11404013 Molecular evolution of Sry and Sox gene. Pubmed 5.284E-30 3.324E-27 2.980E-26 2.326E-26 9 16
8 16306355 The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas. Pubmed 4.266E-29 2.348E-26 2.105E-25 1.878E-25 9 19
9 11071752 Phylogeny of the SOX family of developmental transcription factors based on sequence and structural indicators. Pubmed 7.277E-28 3.204E-25 2.873E-24 3.204E-24 8 11
10 7590241 Developmental-specific activity of the FGF-4 enhancer requires the synergistic action of Sox2 and Oct-3. Pubmed 7.277E-28 3.204E-25 2.873E-24 3.204E-24 8 11
11 12194848 Twenty pairs of sox: extent, homology, and nomenclature of the mouse and human sox transcription factor gene families. Pubmed 5.675E-27 2.271E-24 2.037E-23 2.499E-23 8 13
12 10729834 Pairing SOX off: with partners in the regulation of embryonic development. Pubmed 1.501E-21 5.083E-19 4.558E-18 6.608E-18 6 7
13 1614875 A conserved family of genes related to the testis determining gene, SRY. Pubmed 1.501E-21 5.083E-19 4.558E-18 6.608E-18 6 7
14 17084361 SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Pubmed 3.911E-21 1.230E-18 1.103E-17 1.722E-17 7 21
15 22344693 Deciphering the Sox-Oct partner code by quantitative cooperativity measurements. Pubmed 9.900E-20 2.906E-17 2.606E-16 4.359E-16 6 11
16 19369396 A cluster of three long-range enhancers directs regional Shh expression in the epithelial linings. Pubmed 2.879E-17 7.923E-15 7.105E-14 1.268E-13 6 24
17 18703590 The transcription factor Sox5 modulates Sox10 function during melanocyte development. Pubmed 1.473E-16 3.603E-14 3.231E-13 6.486E-13 5 9
18 12100890 Matching SOX: partner proteins and co-factors of the SOX family of transcriptional regulators. Pubmed 1.473E-16 3.603E-14 3.231E-13 6.486E-13 5 9
19 19723505 SOX1 links the function of neural patterning and Notch signalling in the ventral spinal cord during the neuron-glial fate switch. Pubmed 1.573E-16 3.646E-14 3.270E-13 6.928E-13 6 31
20 28118982 SOX4 regulates gonad morphogenesis and promotes male germ cell differentiation in mice. Pubmed 2.873E-16 6.176E-14 5.538E-13 1.265E-12 6 34
21 26525805 Sox13 functionally complements the related Sox5 and Sox6 as important developmental modulators in mouse spinal cord oligodendrocytes. Pubmed 2.946E-16 6.176E-14 5.538E-13 1.297E-12 5 10
22 23884650 SOX2-LIN28/let-7 pathway regulates proliferation and neurogenesis in neural precursors. Pubmed 1.504E-15 3.009E-13 2.699E-12 6.621E-12 5 13
23 20356956 Ets1 is required for proper migration and differentiation of the cardiac neural crest. Pubmed 1.357E-14 2.598E-12 2.330E-11 5.976E-11 5 19
24 26504244 SoxC transcription factors are essential for the development of the inner ear. Pubmed 2.792E-14 5.121E-12 4.593E-11 1.229E-10 4 5
25 7821514 Sox gene expression during neuronal development. Pubmed 8.373E-14 1.475E-11 1.322E-10 3.687E-10 4 6
26 29031500 Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Pubmed 3.253E-13 5.509E-11 4.940E-10 1.432E-9 7 246
27 17875931 Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. Pubmed 3.906E-13 6.370E-11 5.712E-10 1.720E-9 4 8
28 22678282 Cis-regulatory control of corticospinal system development and evolution. Pubmed 2.760E-12 4.341E-10 3.892E-9 1.215E-8 4 12
29 25452386 SOXC proteins amplify canonical WNT signaling to secure nonchondrocytic fates in skeletogenesis. Pubmed 3.987E-12 6.053E-10 5.428E-9 1.755E-8 4 13
30 15893981 Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Pubmed 7.608E-12 1.015E-9 9.103E-9 3.350E-8 4 15
31 26203155 Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes. Pubmed 7.608E-12 1.015E-9 9.103E-9 3.350E-8 4 15
32 25652387 SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models. Pubmed 7.608E-12 1.015E-9 9.103E-9 3.350E-8 4 15
33 24257626 Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes. Pubmed 7.608E-12 1.015E-9 9.103E-9 3.350E-8 4 15
34 25761772 SOXC Transcription Factors Induce Cartilage Growth Plate Formation in Mouse Embryos by Promoting Noncanonical WNT Signaling. Pubmed 1.326E-11 1.717E-9 1.540E-8 5.839E-8 4 17
35 18403418 The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
36 21401405 Electroporation-mediated transfer of SOX trio genes (SOX-5, SOX-6, and SOX-9) to enhance the chondrogenesis of mesenchymal stem cells. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
37 28630873 An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
38 18559420 L-Sox5 and Sox6 drive expression of the aggrecan gene in cartilage by securing binding of Sox9 to a far-upstream enhancer. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
39 26045173 Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
40 26150426 The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
41 15529345 The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
42 21728837 SOX trio decrease in the articular cartilage with the advancement of osteoarthritis. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
43 28687615 SOX5/6/21 Prevent Oncogene-Driven Transformation of Brain Stem Cells. Pubmed 2.370E-11 2.426E-9 2.176E-8 1.043E-7 3 3
44 25043184 Sox4 links tumor suppression to accelerated aging in mice by modulating stem cell activation. Pubmed 2.698E-11 2.700E-9 2.421E-8 1.188E-7 4 20
45 20932939 Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus. Pubmed 5.580E-11 5.460E-9 4.896E-8 2.457E-7 6 243
46 26998831 SOXC and MiR17-92 gene expression profiling defines two subgroups with different clinical outcome in mantle cell lymphoma. Pubmed 9.476E-11 8.181E-9 7.336E-8 4.172E-7 3 4
47 19759178 Sox9 family members negatively regulate maturation and calcification of chondrocytes through up-regulation of parathyroid hormone-related protein. Pubmed 9.476E-11 8.181E-9 7.336E-8 4.172E-7 3 4
48 22085726 Sequentially acting Sox transcription factors in neural lineage development. Pubmed 9.476E-11 8.181E-9 7.336E-8 4.172E-7 3 4
49 21262861 SHOX interacts with the chondrogenic transcription factors SOX5 and SOX6 to activate the aggrecan enhancer. Pubmed 9.476E-11 8.181E-9 7.336E-8 4.172E-7 3 4
50 12446692 Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins. Pubmed 9.476E-11 8.181E-9 7.336E-8 4.172E-7 3 4
Show 45 more annotations

9: Interaction [Display Chart] 12 input genes in category / 495 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:SOX5 SOX5 interactions 1.758E-11 8.702E-9 5.902E-8 8.702E-9 5 35
2 int:SOX6 SOX6 interactions 1.931E-7 4.778E-5 3.241E-4 9.557E-5 3 18
3 int:SOX21 SOX21 interactions 2.525E-6 4.167E-4 2.826E-3 1.250E-3 2 4
4 int:SOX11 SOX11 interactions 6.309E-6 7.692E-4 5.217E-3 3.123E-3 2 6
5 int:PAX6 PAX6 interactions 9.236E-6 7.692E-4 5.217E-3 4.572E-3 3 63
6 int:UBE2I UBE2I interactions 9.323E-6 7.692E-4 5.217E-3 4.615E-3 5 476
7 int:POU3F3 POU3F3 interactions 1.512E-5 1.069E-3 7.254E-3 7.486E-3 2 9
8 int:SOX13 SOX13 interactions 1.890E-5 1.169E-3 7.931E-3 9.354E-3 2 10
9 int:POU3F2 POU3F2 interactions 2.309E-5 1.270E-3 8.613E-3 1.143E-2 2 11
10 int:SOX2 SOX2 interactions 7.884E-5 3.567E-3 2.419E-2 3.903E-2 4 367
11 int:CTBP2 CTBP2 interactions 7.926E-5 3.567E-3 2.419E-2 3.923E-2 3 129
12 int:SUMO1 SUMO1 interactions 2.196E-4 8.752E-3
5.936E-2
1.087E-1
 3 182
13 int:CHD7 CHD7 interactions 2.475E-4 8.752E-3
5.936E-2
1.225E-1
 2 35
14 int:PHC3 PHC3 interactions 2.475E-4 8.752E-3
5.936E-2
1.225E-1
 2 35
15 int:ZBTB7A ZBTB7A interactions 2.921E-4 9.640E-3
6.539E-2
1.446E-1
 2 38
16 int:ALX4 ALX4 interactions 3.922E-4 1.213E-2
8.230E-2
1.941E-1
 2 44
17 int:CEP85 CEP85 interactions 4.477E-4 1.231E-2
8.350E-2
2.216E-1
 2 47
18 int:NR5A1 NR5A1 interactions 4.477E-4 1.231E-2
8.350E-2
2.216E-1
 2 47
19 int:DACH1 DACH1 interactions 4.867E-4 1.268E-2
8.600E-2
2.409E-1
 2 49
20 int:SPEN SPEN interactions 7.054E-4 1.746E-2
1.184E-1
3.492E-1
 2 59
21 int:NSD3 NSD3 interactions 8.556E-4 2.017E-2
1.368E-1
4.235E-1
 2 65
22 int:HIST2H3A HIST2H3A interactions 9.635E-4 2.168E-2
1.470E-1
4.770E-1
 2 69
23 int:SUMO3 SUMO3 interactions 1.261E-3 2.683E-2
1.820E-1
6.240E-1
 2 79
24 int:NANOGNB NANOGNB interactions 1.355E-3 2.683E-2
1.820E-1
6.709E-1
 1 2
25 int:RP1L1 RP1L1 interactions 1.355E-3 2.683E-2
1.820E-1
6.709E-1
 1 2
26 int:TCF12 TCF12 interactions 1.561E-3 2.972E-2
2.016E-1
7.727E-1
 2 88
27 int:AURKA AURKA interactions 1.745E-3 3.199E-2
2.170E-1
8.637E-1
 3 371
28 int:TERT TERT interactions 1.970E-3 3.245E-2
2.201E-1
9.752E-1
 2 99
29 int:PRRX2 PRRX2 interactions 2.032E-3 3.245E-2
2.201E-1
1.000E0
 1 3
30 int:RGSL1 RGSL1 interactions 2.032E-3 3.245E-2
2.201E-1
1.000E0
 1 3
31 int:SCX SCX interactions 2.032E-3 3.245E-2
2.201E-1
1.000E0
 1 3
32 int:SMAD7 SMAD7 interactions 2.339E-3 3.617E-2
2.454E-1
1.000E0
 2 108
33 int:SOX12 SOX12 interactions 2.709E-3 3.871E-2
2.626E-1
1.000E0
 1 4
34 int:SOX1 SOX1 interactions 2.709E-3 3.871E-2
2.626E-1
1.000E0
 1 4
35 int:CTR9 CTR9 interactions 2.737E-3 3.871E-2
2.626E-1
1.000E0
 2 117
36 int:CDC23 CDC23 interactions 3.117E-3 4.285E-2
2.907E-1
1.000E0
 2 125
37 int:SOX14 SOX14 interactions 3.385E-3 4.529E-2
3.072E-1
1.000E0
 1 5
Show 32 more annotations

10: Cytoband [Display Chart] 12 input genes in category / 12 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 13q31-q32 13q31-q32 6.923E-4 6.230E-3 1.933E-2 8.308E-3 1 2
2 3q26.3-q27 3q26.3-q27 1.038E-3 6.230E-3 1.933E-2 1.246E-2 1 3
3 17q23 17q23 3.457E-3 1.383E-2 4.291E-2 4.149E-2 1 10
4 2p25 2p25 6.215E-3 1.587E-2 4.925E-2
7.458E-2
 1 18
5 Xq27.1 Xq27.1 7.247E-3 1.587E-2 4.925E-2
8.697E-2
 1 21
6 11p15.3 11p15.3 7.935E-3 1.587E-2 4.925E-2
9.522E-2
 1 23
7 12p12.1 12p12.1 1.034E-2 1.772E-2
5.500E-2
1.241E-1
 1 30
8 6p22.3 6p22.3 1.581E-2 2.245E-2
6.966E-2
1.897E-1
 1 46
9 1q32 1q32 1.684E-2 2.245E-2
6.966E-2
2.020E-1
 1 49
10 20q13.33 20q13.33 3.005E-2 3.315E-2
1.029E-1
3.606E-1
 1 88
11 22q13.1 22q13.1 3.039E-2 3.315E-2
1.029E-1
3.646E-1
 1 89
12 20p13 20p13 3.475E-2 3.475E-2
1.078E-1
4.170E-1
 1 102
Show 7 more annotations

11: Transcription Factor Binding Site [Display Chart] 12 input genes in category / 236 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$NFAT Q6 V$NFAT Q6 6.586E-5 1.554E-2
9.392E-2
 1.554E-2 4 194
2 AAANWWTGC UNKNOWN AAANWWTGC UNKNOWN 9.802E-4 3.104E-2
1.876E-1
2.313E-1
 3 168
3 V$NKX61 01 V$NKX61 01 1.316E-3 3.104E-2
1.876E-1
3.106E-1
 3 186
4 TCCATTKW UNKNOWN TCCATTKW UNKNOWN 1.421E-3 3.104E-2
1.876E-1
3.353E-1
 3 191
5 V$SOX9 B1 V$SOX9 B1 1.442E-3 3.104E-2
1.876E-1
3.404E-1
 3 192
6 V$AP2ALPHA 01 V$AP2ALPHA 01 1.508E-3 3.104E-2
1.876E-1
3.559E-1
 3 195
7 V$NFKAPPAB65 01 V$NFKAPPAB65 01 1.530E-3 3.104E-2
1.876E-1
3.612E-1
 3 196
8 V$GATA3 01 V$GATA3 01 1.576E-3 3.104E-2
1.876E-1
3.719E-1
 3 198
9 V$SRY 02 V$SRY 02 1.599E-3 3.104E-2
1.876E-1
3.773E-1
 3 199
10 V$AP2GAMMA 01 V$AP2GAMMA 01 1.646E-3 3.104E-2
1.876E-1
3.883E-1
 3 201
11 V$AREB6 04 V$AREB6 04 1.816E-3 3.104E-2
1.876E-1
4.285E-1
 3 208
12 CTGRYYYNATT UNKNOWN CTGRYYYNATT UNKNOWN 1.841E-3 3.104E-2
1.876E-1
4.344E-1
 2 53
13 V$SOX5 01 V$SOX5 01 1.917E-3 3.104E-2
1.876E-1
4.525E-1
 3 212
14 V$CREL 01 V$CREL 01 1.996E-3 3.104E-2
1.876E-1
4.711E-1
 3 215
15 V$NFAT Q4 01 V$NFAT Q4 01 1.996E-3 3.104E-2
1.876E-1
4.711E-1
 3 215
16 V$GFI1 01 V$GFI1 01 2.104E-3 3.104E-2
1.876E-1
4.966E-1
 3 219
17 V$NFKB C V$NFKB C 2.274E-3 3.156E-2
1.907E-1
5.365E-1
 3 225
18 GCTNWTTGK UNKNOWN GCTNWTTGK UNKNOWN 3.000E-3 3.933E-2
2.377E-1
7.079E-1
 3 248
Show 13 more annotations

12: Gene Family [Display Chart] 12 input genes in category / 1 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 757 SRY-boxes genenames.org 1.841E-38 1.841E-38 1.841E-38 1.841E-38 12 19

13: Coexpression [Display Chart] 12 input genes in category / 1095 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16546165-table5 Mouse StemCell Williams06 23genes GeneSigDB 1.410E-7 8.669E-5 6.568E-4 1.544E-4 3 21
2 M14079 Breast cancer compendium: 100 transcription regulators showing most correlated expression with the 9 'embryonic stem cell' transcription factors that are preferentially and coordinately overexpressed in the high-grade, ER-negative breast cancer tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.583E-7 8.669E-5 6.568E-4 1.734E-4 4 100
3 19286929-SuppTable2i Mouse Lung Rangasamy09 248genes GeneSigDB 1.269E-6 4.276E-4 3.240E-3 1.389E-3 4 168
4 M2115 Genes correlated with proneural type of glioblastoma multiforme tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.562E-6 4.276E-4 3.240E-3 1.711E-3 4 177
5 18308945-Table3 Human StemCell Huang08 60genes NSCs GeneSigDB 2.322E-6 5.085E-4 3.853E-3 2.543E-3 3 52
6 15466718-Table6 Mouse Brain Williams04 20genes GeneSigDB 4.196E-5 7.291E-3
5.524E-2
 4.595E-2 2 19
7 12538167-Figure2A Human Breast Bertucci02 23genes GeneSigDB 4.661E-5 7.291E-3
5.524E-2
5.104E-2
 2 20
8 20145155-Table1 Human StemCell Lottaz10 30genes GeneSigDB 9.252E-5 1.113E-2
8.434E-2
1.013E-1
 2 28
9 M2148 Human orthologs of genes down-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [GeneID=4605]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.033E-4 1.113E-2
8.434E-2
1.131E-1
 3 184
10 M7999 Selected gradually up-regulated genes whose expression profile follows that of HEMGN [GeneID=55363] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.137E-4 1.113E-2
8.434E-2
1.245E-1
 2 31
11 M2726 Genes down-regulated in MCF-7 cells (breast cancer) positive for ESR1 [Gene ID=2099] MCF-7 cells (breast cancer) stably over-expressing constitutively active RAF1 [Gene ID=5894] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.208E-4 1.113E-2
8.434E-2
1.322E-1
 3 194
12 16762588-Table2 Human HeadandNeck Patel06 45genes GeneSigDB 1.290E-4 1.113E-2
8.434E-2
1.413E-1
 2 33
13 M8836 Genes up-regulated in hematopoietic stem cells versus multipotent progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.322E-4 1.113E-2
8.434E-2
1.447E-1
 3 200
14 M802 Selected gradually up-regulated genes whose expression profile follows that of HBZ [GeneID=3050] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.999E-4 1.460E-2
1.106E-1
2.189E-1
 2 41
15 20035825-TableS8b Human Lung Mikkonen10 59genes GeneSigDB 1.999E-4 1.460E-2
1.106E-1
2.189E-1
 2 41
16 M15031 Genes up-regulated in MCF10A cells (breast cancer) by expression of LSM1 [GeneID=27257] off a letiviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.305E-4 1.577E-2
1.195E-1
2.524E-1
 2 44
17 16254190-Table1 Mouse Skin Zhang05 51genes GeneSigDB 2.631E-4 1.695E-2
1.284E-1
2.881E-1
 2 47
18 M2700 Genes down-regulated in bone relapse of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.974E-4 3.026E-2
2.292E-1
5.446E-1
 3 314
19 M15973 Human orthologs of BMYB [GeneID=4605] target genes in zebra fish, identified as commonly changed in the BMYB loss of function mutant crb ('crush and burn') and after knockdown of BMYB by morpholino. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.349E-4 3.449E-2
2.613E-1
6.952E-1
 2 73
20 M2879 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.379E-4 3.449E-2
2.613E-1
6.985E-1
 3 342
21 M5536 Genes up-regulated and displaying increased copy number in glioblastoma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.700E-4 3.449E-2
2.613E-1
7.337E-1
 2 75
22 M1676 Genes whose expression negatively correlated with that of SMARCA2 [GeneID=6595] in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.168E-4 3.449E-2
2.613E-1
7.849E-1
 3 356
23 15843827-TableS5 Human Leukemia Andersson05 100genes AMLVsALL GeneSigDB 7.245E-4 3.449E-2
2.613E-1
7.933E-1
 2 78
24 M9678 Genes regulated by ESR1 [GeneID=2099] in MCF-7 cells (breast cancer). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.595E-4 3.765E-2
2.852E-1
9.412E-1
 2 85
25 M2021 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 2. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.595E-4 3.765E-2
2.852E-1
9.412E-1
 2 85
26 M4619 Genes up-regulated in prostate cancer samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.094E-3 4.337E-2
3.286E-1
1.000E0
 2 96
27 17660535-TableS7 Mouse InnerEar Sajan08 109genes GeneSigDB 1.117E-3 4.337E-2
3.286E-1
1.000E0
 2 97
28 19269367-TableS1 Mouse StemCell vanderFlier09 134genes GeneSigDB 1.140E-3 4.337E-2
3.286E-1
1.000E0
 2 98
29 19168792-TableS2 Human Leukemia Figueroa09 567genes GeneSigDB 1.149E-3 4.337E-2
3.286E-1
1.000E0
 3 419
30 21205295-TableS2 Mouse Viral Buonomo11 116genes GeneSigDB 1.307E-3 4.698E-2
3.560E-1
1.000E0
 2 105
31 M18762 'Late-TGFB1 signature': genes overexpressed in primary hepatocytes at a late phase of TGFB1 [GeneID=7040] treatment; is associated with a more invasive phenotype. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.407E-3 4.698E-2
3.560E-1
1.000E0
 2 109
32 18698033-tableS1-ESR1 Human Breast Desmedt08 469genes ESR1 Module GeneSigDB 1.411E-3 4.698E-2
3.560E-1
1.000E0
 3 450
33 17430594-table4 Human Prostate Chandran07 154genes GeneSigDB 1.433E-3 4.698E-2
3.560E-1
1.000E0
 2 110
34 18689800-TableS6 Human EmbryonicStemCell Thomas08 113genes GeneSigDB 1.459E-3 4.698E-2
3.560E-1
1.000E0
 2 111
35 M14146 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G1, defined by unsupervised clustering MSigDB C2: CGP Curated Gene Sets (v6.0) 1.511E-3 4.728E-2
3.582E-1
1.000E0
 2 113
Show 30 more annotations

14: Coexpression Atlas [Display Chart] 12 input genes in category / 1815 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s11 intermediate neurons Subtype intermediate neurons s11 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s11 intermediate neurons Subtype intermediate neurons s11 Top 100 Genes 6.686E-13 1.200E-9 9.694E-9 1.214E-9 7 157
2 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s7 intermediate neurons Subtype intermediate neurons s7 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s7 intermediate neurons Subtype intermediate neurons s7 Top 100 Genes 1.907E-12 1.200E-9 9.694E-9 3.462E-9 7 182
3 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s4 intermediate neurons Subtype intermediate neurons s4 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s4 intermediate neurons Subtype intermediate neurons s4 Top 100 Genes 1.983E-12 1.200E-9 9.694E-9 3.599E-9 7 183
4 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s2 intermediate neurons Subtype intermediate neurons s2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s2 intermediate neurons Subtype intermediate neurons s2 Top 100 Genes 1.690E-10 7.667E-8 6.196E-7 3.067E-7 6 168
5 6mo cortical organoids wt 6mo cortical organoids wt pan subtypes intermediate neurons Overall Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt pan subtypes intermediate neurons Overall Top 100 Genes 1.271E-9 4.613E-7 3.728E-6 2.306E-6 5 98
6 gudmap developingGonad e12.5 epididymis k4 1000 DevelopingGonad e12.5 epididymis emap-29139 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.016E-9 1.215E-6 9.818E-6 7.289E-6 5 123
7 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s10 intermediate neurons Subtype intermediate neurons s10 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s10 intermediate neurons Subtype intermediate neurons s10 Top 100 Genes 6.187E-9 1.604E-6 1.296E-5 1.123E-5 5 134
8 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.3.2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.3.2 Top 100 Genes 7.176E-9 1.628E-6 1.316E-5 1.302E-5 5 138
9 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s9 intermediate neurons Subtype intermediate neurons s9 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s9 intermediate neurons Subtype intermediate neurons s9 Top 100 Genes 1.206E-8 2.076E-6 1.678E-5 2.189E-5 5 153
10 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Cspg5 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Cspg5 Top 200 Genes BrainMap 1.273E-8 2.076E-6 1.678E-5 2.310E-5 6 345
11 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Dlx1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Dlx1 Top 200 Genes BrainMap 1.318E-8 2.076E-6 1.678E-5 2.391E-5 6 347
12 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s1 intermediate neurons Subtype intermediate neurons s1 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s1 intermediate neurons Subtype intermediate neurons s1 Top 100 Genes 1.373E-8 2.076E-6 1.678E-5 2.492E-5 5 157
13 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s12 intermediate neurons Subtype intermediate neurons s12 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s12 intermediate neurons Subtype intermediate neurons s12 Top 100 Genes 1.558E-8 2.175E-6 1.758E-5 2.827E-5 5 161
14 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s5 intermediate neurons Subtype intermediate neurons s5 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s5 intermediate neurons Subtype intermediate neurons s5 Top 100 Genes 2.047E-8 2.653E-6 2.144E-5 3.714E-5 5 170
15 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s3 intermediate neurons Subtype intermediate neurons s3 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s3 intermediate neurons Subtype intermediate neurons s3 Top 100 Genes 2.367E-8 2.762E-6 2.232E-5 4.295E-5 5 175
16 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.1 Intermediate.1 Subtype int.01.7 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.1 Intermediate.1 Subtype int.01.7 Top 100 Genes 2.435E-8 2.762E-6 2.232E-5 4.420E-5 5 176
17 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s14 intermediate neurons Subtype intermediate neurons s14 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s14 intermediate neurons Subtype intermediate neurons s14 Top 100 Genes 2.960E-8 3.157E-6 2.552E-5 5.373E-5 5 183
18 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Overall Top 200 Genes BrainMap 3.479E-8 3.157E-6 2.552E-5 6.315E-5 5 189
19 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q Polydendrocyte.polydendrocytes.Bmp4 C1q Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q Polydendrocyte.polydendrocytes.Bmp4 C1q Overall Top 200 Genes BrainMap 3.479E-8 3.157E-6 2.552E-5 6.315E-5 5 189
20 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q Polydendrocyte.polydendrocytes.Bmp4 C1q Top 200 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q Polydendrocyte.polydendrocytes.Bmp4 C1q Top 200 BrainMap 3.479E-8 3.157E-6 2.552E-5 6.315E-5 5 189
21 Facebase RNAseq e10.5 Neural Epithelium Overlying Central Eminence 500 FacebaseRNAseq e10.5 Neural Epithelium Overlying Central Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 1.112E-7 9.610E-6 7.766E-5 2.018E-4 6 497
22 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Thalamus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Thalamus Top 200 Genes BrainMap 1.244E-7 1.027E-5 8.296E-5 2.258E-4 5 244
23 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr SubstantiaNigra Top 200 Genes BrainMap 1.322E-7 1.031E-5 8.333E-5 2.400E-4 5 247
24 6mo cortical organoids wt 6mo cortical organoids wt nan static Subtype 4 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt nan static Subtype 4 Top 100 Genes 1.363E-7 1.031E-5 8.333E-5 2.475E-4 4 91
25 6mo cortical organoids wt 6mo cortical organoids wt nan static Subtype 5 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt nan static Subtype 5 Top 100 Genes 1.622E-7 1.178E-5 9.518E-5 2.944E-4 4 95
26 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Entopeduncular Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Entopeduncular Top 200 Genes BrainMap 2.422E-7 1.691E-5 1.366E-4 4.396E-4 5 279
27 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr PosteriorCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr PosteriorCortex Top 200 Genes BrainMap 2.645E-7 1.778E-5 1.437E-4 4.801E-4 5 284
28 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Striatum Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Striatum Top 200 Genes BrainMap 3.471E-7 2.250E-5 1.818E-4 6.299E-4 5 300
29 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Subtype polydendrocytes.Bmp4 C1q Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Subtype polydendrocytes.Bmp4 C1q Top 200 Genes 4.350E-7 2.632E-5 2.127E-4 7.895E-4 5 314
30 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q Top 200 Genes BrainMap 4.350E-7 2.632E-5 2.127E-4 7.895E-4 5 314
31 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Bmp4 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Bmp4 Top 200 Genes BrainMap 4.851E-7 2.840E-5 2.295E-4 8.804E-4 5 321
32 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr GlobusPallidus Top 200 Genes BrainMap 5.397E-7 3.061E-5 2.474E-4 9.795E-4 5 328
33 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Pdgfa Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Pdgfa Top 200 Genes BrainMap 8.428E-7 4.492E-5 3.630E-4 1.530E-3 5 359
34 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Hippocampus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Hippocampus Top 200 Genes BrainMap 8.428E-7 4.492E-5 3.630E-4 1.530E-3 5 359
35 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr FrontalCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr FrontalCortex Top 200 Genes BrainMap 8.663E-7 4.492E-5 3.630E-4 1.572E-3 5 361
36 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.3.1 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.3.1 Top 100 Genes 1.795E-6 8.667E-5 7.004E-4 3.258E-3 4 173
37 gudmap developingGonad e12.5 epididymis k2 500 DevelopingGonad e12.5 epididymis emap-29139 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.901E-6 8.667E-5 7.004E-4 3.451E-3 3 46
38 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Overall Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.056E-6 8.667E-5 7.004E-4 3.732E-3 4 179
39 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hNProg Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 2.056E-6 8.667E-5 7.004E-4 3.732E-3 4 179
40 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis Neurogenesis Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neurogenesis Neurogenesis Overall Top 200 Genes BrainMap 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
41 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Neurogenesis Overall Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Neurogenesis Overall Top 200 Genes 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
42 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature.Sox4 Neurogenesis.neurons.immature.Sox4 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature.Sox4 Neurogenesis.neurons.immature.Sox4 Overall Top 200 Genes BrainMap 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
43 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature Neurogenesis.neurons.immature Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature Neurogenesis.neurons.immature Overall Top 200 Genes BrainMap 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
44 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature Neurogenesis.neurons.immature Top 200 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature Neurogenesis.neurons.immature Top 200 BrainMap 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
45 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.1 Intermediate.1 Subtype int.01.10 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.1 Intermediate.1 Subtype int.01.10 Top 100 Genes 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
46 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis Neurogenesis Top 200 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis Neurogenesis Top 200 BrainMap 2.197E-6 8.667E-5 7.004E-4 3.987E-3 4 182
47 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Overall Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 2.344E-6 8.864E-5 7.163E-4 4.255E-3 4 185
48 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hOPC Top 200 GSE76381_EmbryoMoleculeCountsPMLog2 2.344E-6 8.864E-5 7.163E-4 4.255E-3 4 185
49 gudmap developingGonad e12.5 testes k4 1000 DevelopingGonad e12.5 testes emap-29069 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.452E-6 8.894E-5 7.187E-4 4.450E-3 3 50
50 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Overall Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Overall Top 200 Genes 2.499E-6 8.894E-5 7.187E-4 4.536E-3 4 188
Show 45 more annotations

15: Computational [Display Chart] 10 input genes in category / 60 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 12 input genes in category / 740 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GGGGCCC,MIR-296:MSigDB GGGGCCC,MIR-296:MSigDB MSigDB 3.750E-10 2.775E-7 1.993E-6 2.775E-7 4 69
2 hsa-miR-212:PITA hsa-miR-212:PITA TOP PITA 1.678E-9 4.140E-7 2.974E-6 1.242E-6 5 338
3 hsa-miR-132:PITA hsa-miR-132:PITA TOP PITA 1.678E-9 4.140E-7 2.974E-6 1.242E-6 5 338
4 GACTGTT,MIR-212:MSigDB GACTGTT,MIR-212:MSigDB MSigDB 9.700E-9 1.436E-6 1.031E-5 7.178E-6 4 154
5 GACTGTT,MIR-132:MSigDB GACTGTT,MIR-132:MSigDB MSigDB 9.700E-9 1.436E-6 1.031E-5 7.178E-6 4 154
6 hsa-miR-499-5p:PITA hsa-miR-499-5p:PITA TOP PITA 4.368E-8 4.701E-6 3.378E-5 3.233E-5 4 224
7 TAGCTTT,MIR-9:MSigDB TAGCTTT,MIR-9:MSigDB MSigDB 4.447E-8 4.701E-6 3.378E-5 3.291E-5 4 225
8 AGTCTTA,MIR-499:MSigDB AGTCTTA,MIR-499:MSigDB MSigDB 1.989E-7 1.839E-5 1.322E-4 1.472E-4 3 71
9 hsa-miR-140-5p:Functional MTI Functional MTI miRTarbase 5.782E-7 4.754E-5 3.416E-4 4.279E-4 3 101
10 ATAAGCT,MIR-21:MSigDB ATAAGCT,MIR-21:MSigDB MSigDB 8.781E-7 5.330E-5 3.829E-4 6.498E-4 3 116
11 TTTGCAC,MIR-19A:MSigDB TTTGCAC,MIR-19A:MSigDB MSigDB 9.363E-7 5.330E-5 3.829E-4 6.929E-4 4 483
12 hsa-miR-539:PITA hsa-miR-539:PITA TOP PITA 9.363E-7 5.330E-5 3.829E-4 6.929E-4 4 483
13 TTTGCAC,MIR-19B:MSigDB TTTGCAC,MIR-19B:MSigDB MSigDB 9.363E-7 5.330E-5 3.829E-4 6.929E-4 4 483
14 hsa-miR-1226:PITA hsa-miR-1226:PITA TOP PITA 3.292E-6 1.695E-4 1.218E-3 2.436E-3 3 180
15 hsa-miR-1203:PITA hsa-miR-1203:PITA TOP PITA 3.435E-6 1.695E-4 1.218E-3 2.542E-3 2 17
16 GTTTGTT,MIR-495:MSigDB GTTTGTT,MIR-495:MSigDB MSigDB 7.410E-6 3.308E-4 2.377E-3 5.483E-3 3 236
17 hsa-miR-145-5p:Functional MTI Functional MTI miRTarbase 7.599E-6 3.308E-4 2.377E-3 5.624E-3 3 238
18 hsa-miR-371-5p:PITA hsa-miR-371-5p:PITA TOP PITA 8.087E-6 3.325E-4 2.389E-3 5.984E-3 3 243
19 hsa-miR-132-3p:Functional MTI Functional MTI miRTarbase 9.340E-6 3.445E-4 2.475E-3 6.912E-3 3 255
20 hsa-miR-590-5p:PITA hsa-miR-590-5p:PITA TOP PITA 1.001E-5 3.445E-4 2.475E-3 7.409E-3 3 261
21 hsa-miR-138:PITA hsa-miR-138:PITA TOP PITA 1.024E-5 3.445E-4 2.475E-3 7.580E-3 3 263
22 hsa-miR-21:PITA hsa-miR-21:PITA TOP PITA 1.024E-5 3.445E-4 2.475E-3 7.580E-3 3 263
23 hsa-miR-618:PITA hsa-miR-618:PITA TOP PITA 1.096E-5 3.454E-4 2.481E-3 8.108E-3 3 269
24 hsa-miR-194:PITA hsa-miR-194:PITA TOP PITA 1.120E-5 3.454E-4 2.481E-3 8.289E-3 3 271
25 TGCTTTG,MIR-330:MSigDB TGCTTTG,MIR-330:MSigDB MSigDB 1.738E-5 5.145E-4 3.696E-3 1.286E-2 3 314
26 hsa-miR-216b:PITA hsa-miR-216b:PITA TOP PITA 2.165E-5 6.161E-4 4.426E-3 1.602E-2 3 338
27 hsa-miR-1200:PITA hsa-miR-1200:PITA TOP PITA 2.401E-5 6.559E-4 4.713E-3 1.777E-2 3 350
28 hsa-miR-342-5p:PITA hsa-miR-342-5p:PITA TOP PITA 2.607E-5 6.559E-4 4.713E-3 1.929E-2 2 46
29 hsa-miR-136-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.841E-5 6.559E-4 4.713E-3 2.102E-2 2 48
30 hsa-miR-1252:PITA hsa-miR-1252:PITA TOP PITA 2.856E-5 6.559E-4 4.713E-3 2.113E-2 3 371
31 TTGCACT,MIR-130A:MSigDB TTGCACT,MIR-130A:MSigDB MSigDB 2.925E-5 6.559E-4 4.713E-3 2.165E-2 3 374
32 TTGCACT,MIR-301:MSigDB TTGCACT,MIR-301:MSigDB MSigDB 2.925E-5 6.559E-4 4.713E-3 2.165E-2 3 374
33 TTGCACT,MIR-130B:MSigDB TTGCACT,MIR-130B:MSigDB MSigDB 2.925E-5 6.559E-4 4.713E-3 2.165E-2 3 374
34 CCATCCA,MIR-432:MSigDB CCATCCA,MIR-432:MSigDB MSigDB 3.469E-5 7.550E-4 5.425E-3 2.567E-2 2 53
35 GGCACAT,MIR-455:MSigDB GGCACAT,MIR-455:MSigDB MSigDB 3.738E-5 7.692E-4 5.526E-3 2.766E-2 2 55
36 CTTTGTA,MIR-524:MSigDB CTTTGTA,MIR-524:MSigDB MSigDB 3.816E-5 7.692E-4 5.526E-3 2.824E-2 3 409
37 hsa-miR-555:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.876E-5 7.692E-4 5.526E-3 2.868E-2 2 56
38 TGCACTT,MIR-519B:MSigDB TGCACTT,MIR-519B:MSigDB MSigDB 4.158E-5 7.692E-4 5.526E-3 3.077E-2 3 421
39 TGCACTT,MIR-519A:MSigDB TGCACTT,MIR-519A:MSigDB MSigDB 4.158E-5 7.692E-4 5.526E-3 3.077E-2 3 421
40 TGCACTT,MIR-519C:MSigDB TGCACTT,MIR-519C:MSigDB MSigDB 4.158E-5 7.692E-4 5.526E-3 3.077E-2 3 421
41 hsa-miR-105:PITA hsa-miR-105:PITA TOP PITA 4.519E-5 8.072E-4 5.799E-3 3.344E-2 3 433
42 hsa-miR-579:PITA hsa-miR-579:PITA TOP PITA 4.581E-5 8.072E-4 5.799E-3 3.390E-2 3 435
43 hsa-miR-875-3p:PITA hsa-miR-875-3p:PITA TOP PITA 5.338E-5 9.186E-4 6.600E-3 3.950E-2 3 458
44 hsa-miR-1274b:mirSVR highEffct hsa-miR-1274b:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.512E-5 9.271E-4 6.660E-3 4.079E-2 3 463
45 hsa-miR-3591-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.727E-5 9.418E-4 6.766E-3 4.238E-2 2 68
46 hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA TOP PITA 6.402E-5 1.030E-3 7.400E-3 4.738E-2 3 487
47 hsa-miR-6884-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.604E-5 1.040E-3 7.470E-3 4.887E-2 2 73
48 hsa-miR-21-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.543E-5 1.317E-3 9.463E-3
6.322E-2
 2 83
49 hsa-miR-1251:PITA hsa-miR-1251:PITA TOP PITA 9.826E-5 1.484E-3 1.066E-2
7.271E-2
 2 89
50 hsa-miR-212-3p:Functional MTI Functional MTI miRTarbase 1.096E-4 1.591E-3 1.143E-2
8.112E-2
 2 94
Show 45 more annotations

17: Drug [Display Chart] 12 input genes in category / 3427 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000062286 arsenals Stitch 1.168E-6 3.975E-3 3.465E-2 4.002E-3 3 41
2 4202 DN Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; PC3; HT HG-U133A Broad Institute CMAP Down 2.320E-6 3.975E-3 3.465E-2 7.950E-3 4 193
3 CID000112414 tda-1 Stitch 5.306E-6 6.061E-3
5.283E-2
 1.818E-2 2 7
4 CID000123898 Taylor's blue Stitch 3.853E-5 1.425E-2
1.243E-1
1.321E-1
 2 18
5 7079 DN MG-262; Down 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP Down 9.722E-5 1.425E-2
1.243E-1
3.332E-1
 3 178
6 CID000001456 OD-q Stitch 9.885E-5 1.425E-2
1.243E-1
3.387E-1
 3 179
7 7094 DN lomustine; Down 200; 100uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.005E-4 1.425E-2
1.243E-1
3.444E-1
 3 180
8 5941 DN H-7 dihydrochloride; Down 200; 100uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.038E-4 1.425E-2
1.243E-1
3.558E-1
 3 182
9 1709 DN Adiphenine hydrochloride [50-42-0]; Down 200; 11.4uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.055E-4 1.425E-2
1.243E-1
3.617E-1
 3 183
10 4610 DN Doxorubicin hydrochloride [25316-40-9]; Down 200; 6.8uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.073E-4 1.425E-2
1.243E-1
3.676E-1
 3 184
11 ctd:C471109 4(2'-aminoethyl)amino-1,8-dimethylimidazo(1,2-a)quinoxaline CTD 1.092E-4 1.425E-2
1.243E-1
3.741E-1
 2 30
12 4327 DN Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.107E-4 1.425E-2
1.243E-1
3.795E-1
 3 186
13 5777 DN Spiperone [749-02-0]; Down 200; 10.2uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.107E-4 1.425E-2
1.243E-1
3.795E-1
 3 186
14 1632 DN Rapamycin; Down 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.179E-4 1.425E-2
1.243E-1
4.042E-1
 3 190
15 6644 DN Methapyrilene hydrochloride [135-23-9]; Down 200; 13.4uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.198E-4 1.425E-2
1.243E-1
4.105E-1
 3 191
16 3470 UP Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.217E-4 1.425E-2
1.243E-1
4.169E-1
 3 192
17 4151 UP Methionine sulfoximine (L) [15985-39-4]; Up 200; 22.2uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.235E-4 1.425E-2
1.243E-1
4.234E-1
 3 193
18 CID000656929 ahz Stitch 1.244E-4 1.425E-2
1.243E-1
4.263E-1
 2 32
19 3625 DN Metoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.254E-4 1.425E-2
1.243E-1
4.299E-1
 3 194
20 7435 UP Bupivacaine hydrochloride [18010-40-7]; Up 200; 12.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.274E-4 1.425E-2
1.243E-1
4.365E-1
 3 195
21 2649 DN Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.274E-4 1.425E-2
1.243E-1
4.365E-1
 3 195
22 1666 UP estradiol, USP; Up 200; 0.01uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.293E-4 1.425E-2
1.243E-1
4.431E-1
 3 196
23 6979 DN radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.293E-4 1.425E-2
1.243E-1
4.431E-1
 3 196
24 1686 DN Acetazolamide [59-66-5]; Down 200; 18uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.293E-4 1.425E-2
1.243E-1
4.431E-1
 3 196
25 4296 DN Gossypol [303-45-7]; Down 200; 7.8uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.293E-4 1.425E-2
1.243E-1
4.431E-1
 3 196
26 1497 DN Antipyrine, 4-hydroxy [1672-63-5]; Down 200; 19.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.313E-4 1.425E-2
1.243E-1
4.498E-1
 3 197
27 2638 DN Mimosine [500-44-7]; Down 200; 20.2uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.313E-4 1.425E-2
1.243E-1
4.498E-1
 3 197
28 5393 DN Melatonin [73-31-4]; Down 200; 17.2uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.332E-4 1.425E-2
1.243E-1
4.566E-1
 3 198
29 4187 DN Spectinomycin dihydrochloride [21736-83-4]; Down 200; 9.8uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.332E-4 1.425E-2
1.243E-1
4.566E-1
 3 198
30 5003 UP (-)-MK 801 hydrogen maleate [77086-19-2]; Up 200; 11.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.332E-4 1.425E-2
1.243E-1
4.566E-1
 3 198
31 4185 DN Probenecid [57-66-9]; Down 200; 14uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.332E-4 1.425E-2
1.243E-1
4.566E-1
 3 198
32 7190 DN (-)-Cinchonidine [485-71-2]; Down 200; 13.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.352E-4 1.425E-2
1.243E-1
4.635E-1
 3 199
33 3483 UP Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.373E-4 1.425E-2
1.243E-1
4.704E-1
 3 200
34 CID000005137 AC1L1JOO Stitch 1.491E-4 1.503E-2
1.310E-1
5.110E-1
 2 35
35 CID000006623 bisphenol A Stitch 1.893E-4 1.853E-2
1.615E-1
6.486E-1
 3 223
36 CID006540261 EI-N Stitch 2.236E-4 2.129E-2
1.856E-1
7.664E-1
 3 236
37 CID000000602 alanine Stitch 3.285E-4 3.042E-2
2.652E-1
1.000E0
 3 269
38 CID000002956 A25152 Stitch 4.702E-4 3.693E-2
3.219E-1
1.000E0
 2 62
39 CID000152655 2,3-MDA Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
40 CID000088516 N,N-diisopropylbenzamide Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
41 CID000094849 2-pyridinesulfonate Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
42 CID000008423 3,4-dimethoxyamphetamine Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
43 CID000152132 d-CHO Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
44 CID000098528 N-OH MDA Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
45 CID000011460 m-acetanisole Stitch 5.254E-4 3.693E-2
3.219E-1
1.000E0
 1 1
46 CID006399216 kt S Stitch 5.327E-4 3.693E-2
3.219E-1
1.000E0
 2 66
47 ctd:C031463 beta-glycerophosphoric acid CTD 5.654E-4 3.693E-2
3.219E-1
1.000E0
 2 68
48 CID000165331 C-S-S Stitch 7.816E-4 3.693E-2
3.219E-1
1.000E0
 2 80
49 CID000447988 AC1L9LGY Stitch 8.209E-4 3.693E-2
3.219E-1
1.000E0
 2 82
50 CID000001001 phenylethylamine Stitch 9.660E-4 3.693E-2
3.219E-1
1.000E0
 2 89
Show 45 more annotations

18: Disease [Display Chart] 12 input genes in category / 733 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C2936419 46, XX Testicular Disorders of Sex Development DisGeNET Curated 1.084E-8 7.946E-6 5.701E-5 7.946E-6 3 7
2 C3489396 Hypogonadism, Isolated Hypogonadotropic DisGeNET Curated 4.256E-7 1.560E-4 1.119E-3 3.120E-4 4 90
3 C0271623 Hypogonadotropic hypogonadism DisGeNET Curated 6.506E-7 1.590E-4 1.141E-3 4.769E-4 4 100
4 C0014474 Ependymoma DisGeNET Curated 1.352E-6 2.195E-4 1.575E-3 9.911E-4 4 120
5 C0010417 Cryptorchidism DisGeNET Curated 1.498E-6 2.195E-4 1.575E-3 1.098E-3 5 300
6 C2936403 46, XX Disorders of Sex Development DisGeNET Curated 3.014E-6 3.682E-4 2.642E-3 2.209E-3 2 4
7 C1842876 Depressed nasal ridge DisGeNET Curated 6.333E-6 5.674E-4 4.071E-3 4.642E-3 3 51
8 C0266435 Congenital hypoplasia of penis DisGeNET Curated 7.417E-6 5.674E-4 4.071E-3 5.436E-3 4 184
9 C0010606 Adenoid Cystic Carcinoma DisGeNET Curated 7.741E-6 5.674E-4 4.071E-3 5.674E-3 4 186
10 C0018772 Hearing Loss, Partial DisGeNET Curated 7.741E-6 5.674E-4 4.071E-3 5.674E-3 4 186
11 C0750974 Brain Tumor, Primary DisGeNET BeFree 8.876E-6 5.914E-4 4.244E-3 6.506E-3 3 57
12 C0011053 Deafness DisGeNET Curated 9.913E-6 5.931E-4 4.256E-3 7.266E-3 4 198
13 C1384666 hearing impairment DisGeNET Curated 1.052E-5 5.931E-4 4.256E-3 7.711E-3 4 201
14 C2981150 Uranostaphyloschisis DisGeNET Curated 1.347E-5 6.432E-4 4.615E-3 9.875E-3 4 214
15 C0018798 Congenital Heart Defects DisGeNET Curated 1.397E-5 6.432E-4 4.615E-3 1.024E-2 4 216
16 C1848519 WAARDENBURG SYNDROME, TYPE 4A DisGeNET Curated 1.404E-5 6.432E-4 4.615E-3 1.029E-2 2 8
17 C0339789 Congenital deafness DisGeNET Curated 1.670E-5 7.202E-4 5.167E-3 1.224E-2 4 226
18 C0241355 Small testicle DisGeNET Curated 2.116E-5 8.615E-4 6.182E-3 1.551E-2 3 76
19 C0008925 Cleft Palate DisGeNET Curated 2.331E-5 8.993E-4 6.453E-3 1.709E-2 4 246
20 C0751291 Desmoplastic Medulloblastoma DisGeNET Curated 2.755E-5 9.615E-4 6.899E-3 2.019E-2 2 11
21 C0018054 Gonadal Dysgenesis, 46,XY DisGeNET Curated 2.755E-5 9.615E-4 6.899E-3 2.019E-2 2 11
22 C1527349 Ductal Breast Carcinoma DisGeNET BeFree 3.399E-5 1.100E-3 7.896E-3 2.492E-2 3 89
23 C0175754 Agenesis of corpus callosum DisGeNET Curated 3.871E-5 1.100E-3 7.896E-3 2.838E-2 4 280
24 C1704376 Uterine Corpus Carcinosarcoma DisGeNET BeFree 3.903E-5 1.100E-3 7.896E-3 2.861E-2 2 13
25 C1859775 Anterior pituitary hypoplasia DisGeNET Curated 3.903E-5 1.100E-3 7.896E-3 2.861E-2 2 13
26 C0280630 Uterine Carcinosarcoma DisGeNET BeFree 3.903E-5 1.100E-3 7.896E-3 2.861E-2 2 13
27 C1839798 Long nose DisGeNET Curated 5.250E-5 1.425E-3 1.023E-2 3.848E-2 2 15
28 C0206715 Neoplasms, Neuroepithelial DisGeNET BeFree 5.998E-5 1.570E-3 1.127E-2 4.396E-2 2 16
29 C3642345 Luminal A Breast Carcinoma DisGeNET BeFree 6.403E-5 1.607E-3 1.153E-2 4.694E-2 3 110
30 C0031900 Pierre Robin Syndrome DisGeNET Curated 6.795E-5 1.607E-3 1.153E-2 4.980E-2 2 17
31 C1136382 Sclerocystic Ovaries DisGeNET Curated 6.795E-5 1.607E-3 1.153E-2 4.980E-2 2 17
32 C0028738 Nystagmus DisGeNET Curated 7.609E-5 1.697E-3 1.218E-2
5.577E-2
 4 333
33 C0948740 Pituitary hypoplasia DisGeNET Curated 7.641E-5 1.697E-3 1.218E-2
5.601E-2
 2 18
34 C0334634 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse DisGeNET Curated 8.535E-5 1.788E-3 1.283E-2
6.256E-2
 4 343
35 C0432475 XX males DisGeNET Curated 8.536E-5 1.788E-3 1.283E-2
6.257E-2
 2 19
36 C1861922 CAMPOMELIC DYSPLASIA DisGeNET Curated 1.047E-4 2.133E-3 1.530E-2
7.678E-2
 2 21
37 C0036875 Disorders of Sex Development DisGeNET Curated 1.261E-4 2.498E-3 1.792E-2
9.242E-2
 2 23
38 C0338503 Septo-Optic Dysplasia DisGeNET Curated 1.375E-4 2.652E-3 1.903E-2
1.008E-1
 2 24
39 C1836543 Thick vermilion border DisGeNET Curated 1.494E-4 2.671E-3 1.916E-2
1.095E-1
 2 25
40 C1849073 Fused vertebrae DisGeNET Curated 1.494E-4 2.671E-3 1.916E-2
1.095E-1
 2 25
41 C1835763 Vertebral body fusion DisGeNET Curated 1.494E-4 2.671E-3 1.916E-2
1.095E-1
 2 25
42 C0151721 Testicular hypogonadism DisGeNET Curated 2.162E-4 3.699E-3 2.654E-2
1.584E-1
 2 30
43 C0008073 Developmental Disabilities DisGeNET Curated 2.170E-4 3.699E-3 2.654E-2
1.591E-1
 3 166
44 C0020555 Hypertrichosis DisGeNET Curated 2.463E-4 4.087E-3 2.932E-2
1.805E-1
 2 32
45 C0520927 Decreased fertility DisGeNET Curated 2.621E-4 4.087E-3 2.932E-2
1.921E-1
 2 33
46 C0020635 Hypopituitarism DisGeNET Curated 2.621E-4 4.087E-3 2.932E-2
1.921E-1
 2 33
47 C3278509 Spinal fusion DisGeNET Curated 2.621E-4 4.087E-3 2.932E-2
1.921E-1
 2 33
48 C0282160 Aplasia Cutis Congenita DisGeNET Curated 3.329E-4 5.084E-3 3.648E-2
2.440E-1
 3 192
49 C0423112 Short palpebral fissure DisGeNET Curated 3.482E-4 5.105E-3 3.663E-2
2.552E-1
 2 38
50 C0375206 Hemiplegia and hemiparesis DisGeNET Curated 3.482E-4 5.105E-3 3.663E-2
2.552E-1
 2 38
Show 45 more annotations