Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc190_21, positive side

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1: GO: Molecular Function [Display Chart] 21 input genes in category / 54 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0003823 antigen binding 2.822E-29 1.524E-27 6.972E-27 1.524E-27 15 120
2 GO:0042605 peptide antigen binding 1.887E-26 5.095E-25 2.331E-24 1.019E-24 11 32
3 GO:0042277 peptide binding 2.459E-17 4.426E-16 2.025E-15 1.328E-15 12 278
4 GO:0033218 amide binding 8.836E-17 1.193E-15 5.458E-15 4.771E-15 12 309
5 GO:0032395 MHC class II receptor activity 8.508E-13 9.189E-12 4.204E-11 4.594E-11 5 12
6 GO:0046977 TAP binding 4.138E-11 3.724E-10 1.704E-9 2.235E-9 4 7
7 GO:0046703 natural killer cell lectin-like receptor binding 2.477E-10 1.911E-9 8.744E-9 1.338E-8 4 10
8 GO:0030881 beta-2-microglobulin binding 2.015E-7 1.360E-6 6.223E-6 1.088E-5 3 11
9 GO:0023026 MHC class II protein complex binding 1.434E-4 8.602E-4 3.936E-3 7.742E-3 2 16
10 GO:0023023 MHC protein complex binding 2.039E-4 1.101E-3 5.037E-3 1.101E-2 2 19
11 GO:0042288 MHC class I protein binding 2.500E-4 1.228E-3 5.616E-3 1.350E-2 2 21
12 GO:0042287 MHC protein binding 5.499E-4 2.475E-3 1.132E-2 2.970E-2 2 31
13 GO:0030624 U6atac snRNA binding 1.125E-3 4.674E-3 2.139E-2
6.077E-2
 1 1
14 GO:0005151 interleukin-1, type II receptor binding 2.249E-3 7.592E-3 3.474E-2
1.215E-1
 1 2
15 GO:0032394 MHC class Ib receptor activity 2.249E-3 7.592E-3 3.474E-2
1.215E-1
 1 2
16 GO:0015433 peptide antigen-transporting ATPase activity 2.249E-3 7.592E-3 3.474E-2
1.215E-1
 1 2
17 GO:0015440 peptide-transporting ATPase activity 4.494E-3 1.277E-2
5.844E-2
2.427E-1
 1 4
18 GO:0046978 TAP1 binding 4.494E-3 1.277E-2
5.844E-2
2.427E-1
 1 4
19 GO:0046979 TAP2 binding 4.494E-3 1.277E-2
5.844E-2
2.427E-1
 1 4
20 GO:0030621 U4 snRNA binding 5.615E-3 1.516E-2
6.936E-2
3.032E-1
 1 5
21 GO:0005138 interleukin-6 receptor binding 7.852E-3 2.019E-2
9.238E-2
4.240E-1
 1 7
22 GO:0042608 T cell receptor binding 8.969E-3 2.106E-2
9.635E-2
4.843E-1
 1 8
23 GO:1990459 transferrin receptor binding 8.969E-3 2.106E-2
9.635E-2
4.843E-1
 1 8
24 GO:1904680 peptide transmembrane transporter activity 1.120E-2 2.419E-2
1.107E-1
6.048E-1
 1 10
25 GO:0039706 co-receptor binding 1.120E-2 2.419E-2
1.107E-1
6.048E-1
 1 10
26 GO:0017070 U6 snRNA binding 1.231E-2 2.557E-2
1.170E-1
6.649E-1
 1 11
27 GO:1990381 ubiquitin-specific protease binding 1.342E-2 2.685E-2
1.228E-1
7.249E-1
 1 12
28 GO:0070006 metalloaminopeptidase activity 1.897E-2 3.658E-2
1.674E-1
1.000E0
 1 17
29 GO:0005149 interleukin-1 receptor binding 2.228E-2 4.010E-2
1.835E-1
1.000E0
 1 20
30 GO:0042887 amide transmembrane transporter activity 2.228E-2 4.010E-2
1.835E-1
1.000E0
 1 20
Show 25 more annotations

2: GO: Biological Process [Display Chart] 21 input genes in category / 551 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0019882 antigen processing and presentation 3.445E-32 1.898E-29 1.308E-28 1.898E-29 18 232
2 GO:0048002 antigen processing and presentation of peptide antigen 6.055E-24 1.668E-21 1.149E-20 3.336E-21 14 185
3 GO:0060333 interferon-gamma-mediated signaling pathway 3.109E-21 5.709E-19 3.934E-18 1.713E-18 11 85
4 GO:0002483 antigen processing and presentation of endogenous peptide antigen 7.273E-21 1.002E-18 6.903E-18 4.008E-18 8 16
5 GO:0019883 antigen processing and presentation of endogenous antigen 4.264E-20 4.234E-18 2.917E-17 2.349E-17 8 19
6 GO:0002478 antigen processing and presentation of exogenous peptide antigen 4.610E-20 4.234E-18 2.917E-17 2.540E-17 12 166
7 GO:0019884 antigen processing and presentation of exogenous antigen 7.672E-20 6.039E-18 4.161E-17 4.227E-17 12 173
8 GO:0002449 lymphocyte mediated immunity 1.804E-19 1.243E-17 8.563E-17 9.942E-17 13 271
9 GO:0071346 cellular response to interferon-gamma 9.613E-19 5.885E-17 4.055E-16 5.297E-16 11 140
10 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 2.580E-18 1.422E-16 9.795E-16 1.422E-15 7 14
11 GO:0034341 response to interferon-gamma 5.368E-18 2.689E-16 1.853E-15 2.958E-15 11 163
12 GO:0002443 leukocyte mediated immunity 6.491E-18 2.980E-16 2.053E-15 3.577E-15 13 356
13 GO:0001909 leukocyte mediated cytotoxicity 9.425E-16 3.995E-14 2.752E-13 5.193E-13 9 103
14 GO:0042267 natural killer cell mediated cytotoxicity 3.147E-15 1.238E-13 8.532E-13 1.734E-12 8 66
15 GO:0002228 natural killer cell mediated immunity 4.572E-15 1.680E-13 1.157E-12 2.519E-12 8 69
16 GO:0051249 regulation of lymphocyte activation 7.239E-15 2.493E-13 1.718E-12 3.989E-12 12 445
17 GO:0001906 cell killing 1.076E-14 3.487E-13 2.403E-12 5.928E-12 9 134
18 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 5.993E-14 1.835E-12 1.264E-11 3.302E-11 8 94
19 GO:0002250 adaptive immune response 1.203E-13 3.489E-12 2.404E-11 6.629E-11 11 402
20 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent 1.370E-13 3.775E-12 2.601E-11 7.551E-11 5 9
21 GO:0051251 positive regulation of lymphocyte activation 4.379E-13 1.149E-11 7.916E-11 2.413E-10 10 311
22 GO:0001910 regulation of leukocyte mediated cytotoxicity 6.313E-13 1.581E-11 1.089E-10 3.479E-10 7 67
23 GO:0050863 regulation of T cell activation 7.221E-13 1.730E-11 1.192E-10 3.979E-10 10 327
24 GO:0002706 regulation of lymphocyte mediated immunity 9.682E-13 2.223E-11 1.531E-10 5.335E-10 8 132
25 GO:1903037 regulation of leukocyte cell-cell adhesion 1.096E-12 2.323E-11 1.600E-10 6.039E-10 10 341
26 GO:0002696 positive regulation of leukocyte activation 1.096E-12 2.323E-11 1.600E-10 6.039E-10 10 341
27 GO:0034110 regulation of homotypic cell-cell adhesion 1.342E-12 2.738E-11 1.886E-10 7.392E-10 10 348
28 GO:0050870 positive regulation of T cell activation 1.536E-12 3.021E-11 2.081E-10 8.463E-10 9 231
29 GO:0050867 positive regulation of cell activation 1.590E-12 3.021E-11 2.081E-10 8.761E-10 10 354
30 GO:0034112 positive regulation of homotypic cell-cell adhesion 1.863E-12 3.422E-11 2.358E-10 1.027E-9 9 236
31 GO:1903039 positive regulation of leukocyte cell-cell adhesion 2.168E-12 3.854E-11 2.655E-10 1.195E-9 9 240
32 GO:0031341 regulation of cell killing 2.286E-12 3.937E-11 2.713E-10 1.260E-9 7 80
33 GO:0031295 T cell costimulation 2.733E-12 4.563E-11 3.144E-10 1.506E-9 7 82
34 GO:0031294 lymphocyte costimulation 2.982E-12 4.833E-11 3.330E-10 1.643E-9 7 83
35 GO:0042269 regulation of natural killer cell mediated cytotoxicity 4.796E-12 7.551E-11 5.202E-10 2.643E-9 6 42
36 GO:0002715 regulation of natural killer cell mediated immunity 5.570E-12 8.354E-11 5.756E-10 3.069E-9 6 43
37 GO:0034109 homotypic cell-cell adhesion 5.610E-12 8.354E-11 5.756E-10 3.091E-9 10 402
38 GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 7.375E-12 1.069E-10 7.368E-10 4.064E-9 9 275
39 GO:0022409 positive regulation of cell-cell adhesion 7.619E-12 1.076E-10 7.416E-10 4.198E-9 9 276
40 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 8.540E-12 1.162E-10 8.009E-10 4.706E-9 6 46
41 GO:0002683 negative regulation of immune system process 8.650E-12 1.162E-10 8.009E-10 4.766E-9 10 420
42 GO:0022407 regulation of cell-cell adhesion 1.091E-11 1.432E-10 9.864E-10 6.013E-9 10 430
43 GO:0002703 regulation of leukocyte mediated immunity 1.421E-11 1.821E-10 1.255E-9 7.832E-9 8 184
44 GO:0016045 detection of bacterium 1.673E-11 2.095E-10 1.443E-9 9.218E-9 5 20
45 GO:0031343 positive regulation of cell killing 2.083E-11 2.551E-10 1.757E-9 1.148E-8 6 53
46 GO:0098543 detection of other organism 2.194E-11 2.628E-10 1.811E-9 1.209E-8 5 21
47 GO:0032649 regulation of interferon-gamma production 2.720E-11 3.188E-10 2.197E-9 1.499E-8 7 113
48 GO:0032609 interferon-gamma production 5.571E-11 6.395E-10 4.406E-9 3.070E-8 7 125
49 GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent 6.751E-11 7.592E-10 5.231E-9 3.720E-8 6 64
50 GO:0098581 detection of external biotic stimulus 8.668E-11 9.552E-10 6.581E-9 4.776E-8 5 27
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 21 input genes in category / 87 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0042611 MHC protein complex 1.061E-30 9.229E-29 4.660E-28 9.229E-29 12 27
2 GO:0098553 lumenal side of endoplasmic reticulum membrane 4.013E-27 1.164E-25 5.876E-25 3.492E-25 11 29
3 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane 4.013E-27 1.164E-25 5.876E-25 3.492E-25 11 29
4 GO:0098576 lumenal side of membrane 2.241E-26 4.874E-25 2.461E-24 1.949E-24 11 33
5 GO:0012507 ER to Golgi transport vesicle membrane 1.371E-23 2.385E-22 1.204E-21 1.193E-21 11 55
6 GO:0030134 COPII-coated ER to Golgi transport vesicle 2.911E-22 4.221E-21 2.131E-20 2.532E-20 11 71
7 GO:0030176 integral component of endoplasmic reticulum membrane 5.829E-19 7.245E-18 3.658E-17 5.071E-17 11 137
8 GO:0030662 coated vesicle membrane 8.755E-19 8.463E-18 4.273E-17 7.617E-17 11 142
9 GO:0031227 intrinsic component of endoplasmic reticulum membrane 8.755E-19 8.463E-18 4.273E-17 7.617E-17 11 142
10 GO:0030666 endocytic vesicle membrane 2.537E-18 2.207E-17 1.114E-16 2.207E-16 11 156
11 GO:0030658 transport vesicle membrane 2.930E-18 2.317E-17 1.170E-16 2.549E-16 11 158
12 GO:0030135 coated vesicle 3.314E-16 2.403E-15 1.213E-14 2.883E-14 11 241
13 GO:0042612 MHC class I protein complex 3.754E-16 2.512E-15 1.268E-14 3.266E-14 6 11
14 GO:0030139 endocytic vesicle 9.507E-16 5.908E-15 2.983E-14 8.271E-14 11 265
15 GO:0031301 integral component of organelle membrane 1.968E-15 1.142E-14 5.763E-14 1.712E-13 11 283
16 GO:0031300 intrinsic component of organelle membrane 3.233E-15 1.758E-14 8.877E-14 2.813E-13 11 296
17 GO:0042613 MHC class II protein complex 6.485E-15 3.319E-14 1.676E-13 5.642E-13 6 16
18 GO:0030133 transport vesicle 4.243E-14 2.051E-13 1.035E-12 3.692E-12 11 374
19 GO:0010008 endosome membrane 8.621E-14 3.948E-13 1.993E-12 7.500E-12 11 399
20 GO:0044440 endosomal part 2.161E-13 9.401E-13 4.747E-12 1.880E-11 11 434
21 GO:0009897 external side of plasma membrane 3.373E-13 1.398E-12 7.056E-12 2.935E-11 10 310
22 GO:0030669 clathrin-coated endocytic vesicle membrane 1.258E-11 4.973E-11 2.511E-10 1.094E-9 6 50
23 GO:0045334 clathrin-coated endocytic vesicle 8.558E-11 3.237E-10 1.634E-9 7.445E-9 6 68
24 GO:0032588 trans-Golgi network membrane 2.712E-10 9.831E-10 4.963E-9 2.359E-8 6 82
25 GO:0030665 clathrin-coated vesicle membrane 2.921E-10 1.017E-9 5.133E-9 2.541E-8 6 83
26 GO:0030670 phagocytic vesicle membrane 5.103E-9 1.707E-8 8.621E-8 4.439E-7 5 60
27 GO:0030136 clathrin-coated vesicle 1.677E-8 5.404E-8 2.728E-7 1.459E-6 6 162
28 GO:0045335 phagocytic vesicle 3.589E-8 1.115E-7 5.630E-7 3.123E-6 5 88
29 GO:0098791 Golgi subcompartment 3.799E-8 1.140E-7 5.755E-7 3.305E-6 7 326
30 GO:0031984 organelle subcompartment 5.170E-8 1.499E-7 7.569E-7 4.498E-6 7 341
31 GO:0005802 trans-Golgi network 9.301E-8 2.610E-7 1.318E-6 8.092E-6 6 216
32 GO:0031901 early endosome membrane 1.321E-7 3.590E-7 1.813E-6 1.149E-5 5 114
33 GO:0098852 lytic vacuole membrane 4.031E-7 1.031E-6 5.208E-6 3.507E-5 6 277
34 GO:0005765 lysosomal membrane 4.031E-7 1.031E-6 5.208E-6 3.507E-5 6 277
35 GO:0005769 early endosome 8.394E-7 2.086E-6 1.053E-5 7.303E-5 6 314
36 GO:0031902 late endosome membrane 5.416E-6 1.309E-5 6.608E-5 4.712E-4 4 108
37 GO:0046658 anchored component of plasma membrane 1.811E-5 4.259E-5 2.150E-4 1.576E-3 3 47
38 GO:1990712 HFE-transferrin receptor complex 3.224E-5 7.381E-5 3.727E-4 2.805E-3 2 8
39 GO:0005770 late endosome 9.497E-5 2.119E-4 1.070E-3 8.263E-3 4 224
40 GO:0031225 anchored component of membrane 6.908E-4 1.503E-3 7.586E-3
6.010E-2
 3 160
41 GO:0005691 U6atac snRNP 1.102E-3 2.282E-3 1.152E-2
9.585E-2
 1 1
42 GO:0071002 U4atac/U6atac snRNP 1.102E-3 2.282E-3 1.152E-2
9.585E-2
 1 1
43 GO:0032398 MHC class Ib protein complex 2.202E-3 4.456E-3 2.250E-2
1.916E-1
 1 2
44 GO:0071001 U4/U6 snRNP 3.302E-3 6.528E-3 3.296E-2
2.872E-1
 1 3
45 GO:0031905 early endosome lumen 4.400E-3 8.322E-3 4.202E-2
3.828E-1
 1 4
46 GO:0042825 TAP complex 4.400E-3 8.322E-3 4.202E-2
3.828E-1
 1 4
47 GO:1990357 terminal web 5.497E-3 9.963E-3
5.030E-2
4.782E-1
 1 5
48 GO:0042824 MHC class I peptide loading complex 5.497E-3 9.963E-3
5.030E-2
4.782E-1
 1 5
49 GO:0005797 Golgi medial cisterna 1.097E-2 1.947E-2
9.830E-2
9.540E-1
 1 10
50 GO:0070971 endoplasmic reticulum exit site 1.206E-2 2.098E-2
1.059E-1
1.000E0
 1 11
Show 45 more annotations

4: Human Phenotype [Display Chart] 12 input genes in category / 1377 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0002039 Anorexia 6.387E-8 4.638E-5 3.620E-4 8.795E-5 7 177
2 HP:0001097 Keratoconjunctivitis sicca 7.441E-8 4.638E-5 3.620E-4 1.025E-4 5 49
3 HP:0100324 Scleroderma 1.010E-7 4.638E-5 3.620E-4 1.391E-4 5 52
4 HP:0001096 Keratoconjunctivitis 1.478E-7 5.087E-5 3.970E-4 2.035E-4 5 56
5 HP:0000964 Eczema 1.890E-7 5.204E-5 4.062E-4 2.602E-4 7 207
6 HP:0100633 Esophagitis 2.775E-7 6.276E-5 4.899E-4 3.821E-4 6 127
7 HP:0001271 Polyneuropathy 3.191E-7 6.276E-5 4.899E-4 4.393E-4 6 130
8 HP:0002788 Recurrent upper respiratory tract infections 1.463E-6 2.008E-4 1.567E-3 2.014E-3 6 168
9 HP:0002102 Pleuritis 1.722E-6 2.008E-4 1.567E-3 2.371E-3 5 91
10 HP:0001370 Rheumatoid arthritis 1.799E-6 2.008E-4 1.567E-3 2.477E-3 6 174
11 HP:0100326 Immunologic hypersensitivity 1.858E-6 2.008E-4 1.567E-3 2.558E-3 7 289
12 HP:0010280 Stomatitis 2.134E-6 2.008E-4 1.567E-3 2.939E-3 5 95
13 HP:0012387 Bronchitis 2.249E-6 2.008E-4 1.567E-3 3.096E-3 5 96
14 HP:0000491 Keratitis 2.492E-6 2.008E-4 1.567E-3 3.432E-3 5 98
15 HP:0002113 Pulmonary infiltrates 2.664E-6 2.008E-4 1.567E-3 3.668E-3 6 186
16 HP:0001913 Granulocytopenia 2.749E-6 2.008E-4 1.567E-3 3.785E-3 6 187
17 HP:0001739 Abnormality of the nasopharynx 2.836E-6 2.008E-4 1.567E-3 3.905E-3 6 188
18 HP:0011122 Abnormality of skin physiology 2.915E-6 2.008E-4 1.567E-3 4.013E-3 8 464
19 HP:0000509 Conjunctivitis 3.041E-6 2.008E-4 1.567E-3 4.188E-3 5 102
20 HP:0025337 Red eye 3.041E-6 2.008E-4 1.567E-3 4.188E-3 5 102
21 HP:0002115 Sparse or absent hair 3.062E-6 2.008E-4 1.567E-3 4.217E-3 8 467
22 HP:0002321 Vertigo 4.424E-6 2.562E-4 2.000E-3 6.092E-3 5 110
23 HP:0000622 Blurred vision 4.440E-6 2.562E-4 2.000E-3 6.114E-3 4 48
24 HP:0003346 Abnormal immunological laboratory finding 4.558E-6 2.562E-4 2.000E-3 6.277E-3 7 330
25 HP:0002024 Malabsorption 4.652E-6 2.562E-4 2.000E-3 6.406E-3 7 331
26 HP:0001697 Abnormal pericardium morphology 5.055E-6 2.673E-4 2.086E-3 6.960E-3 5 113
27 HP:0011107 Recurrent aphthous stomatitis 5.241E-6 2.673E-4 2.086E-3 7.217E-3 4 50
28 HP:0100827 Lymphocytosis 5.513E-6 2.711E-4 2.116E-3 7.591E-3 5 115
29 HP:0100749 Chest pain 6.050E-6 2.873E-4 2.242E-3 8.331E-3 6 214
30 HP:0200042 Skin ulcer 6.527E-6 2.996E-4 2.338E-3 8.988E-3 5 119
31 HP:0001369 Arthritis 7.590E-6 3.262E-4 2.546E-3 1.045E-2 7 356
32 HP:0000600 Abnormality of the pharynx 7.893E-6 3.262E-4 2.546E-3 1.087E-2 6 224
33 HP:0011034 Amyloidosis 7.996E-6 3.262E-4 2.546E-3 1.101E-2 5 124
34 HP:0006775 Multiple myeloma 8.319E-6 3.262E-4 2.546E-3 1.145E-2 5 125
35 HP:0008047 Abnormality of the vasculature of the eye 8.334E-6 3.262E-4 2.546E-3 1.148E-2 7 361
36 HP:0002331 Recurrent paroxysmal headache 8.528E-6 3.262E-4 2.546E-3 1.174E-2 6 227
37 HP:0001733 Pancreatitis 1.017E-5 3.717E-4 2.901E-3 1.401E-2 6 234
38 HP:0000554 Uveitis 1.048E-5 3.717E-4 2.901E-3 1.443E-2 5 131
39 HP:0000433 Abnormality of the nasal mucosa 1.095E-5 3.717E-4 2.901E-3 1.507E-2 4 60
40 HP:0006530 Interstitial pulmonary abnormality 1.122E-5 3.717E-4 2.901E-3 1.545E-2 6 238
41 HP:0002910 Elevated hepatic transaminase 1.134E-5 3.717E-4 2.901E-3 1.561E-2 7 378
42 HP:0001411 Abnormal liver function tests 1.134E-5 3.717E-4 2.901E-3 1.561E-2 7 378
43 HP:0002027 Abdominal pain 1.195E-5 3.828E-4 2.988E-3 1.646E-2 7 381
44 HP:0001006 Hypotrichosis 1.359E-5 4.251E-4 3.318E-3 1.871E-2 6 246
45 HP:0003881 Humeral sclerosis 1.391E-5 4.251E-4 3.318E-3 1.915E-2 6 247
46 HP:0002090 Pneumonia 1.445E-5 4.251E-4 3.318E-3 1.990E-2 7 392
47 HP:0001751 Vestibular dysfunction 1.451E-5 4.251E-4 3.318E-3 1.998E-2 5 140
48 HP:0100699 Scarring 1.520E-5 4.362E-4 3.404E-3 2.094E-2 7 395
49 HP:0001806 Onycholysis 1.641E-5 4.562E-4 3.561E-3 2.260E-2 3 21
50 HP:0011495 Abnormal corneal epithelium morphology 1.666E-5 4.562E-4 3.561E-3 2.293E-2 5 144
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 9 input genes in category / 311 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0005078 abnormal cytotoxic T cell physiology 3.599E-9 1.119E-6 7.073E-6 1.119E-6 5 83
2 MP:0004392 abnormal CD8-positive, alpha-beta T cell physiology 1.967E-8 3.059E-6 1.933E-5 6.117E-6 5 116
3 MP:0001841 decreased level of surface class I molecules 7.466E-8 7.740E-6 4.890E-5 2.322E-5 3 11
4 MP:0001839 abnormal level of surface class I molecules 1.293E-7 1.005E-5 6.352E-5 4.021E-5 3 13
5 MP:0001836 abnormal antigen presentation via MHC class I 2.055E-7 1.278E-5 8.077E-5 6.392E-5 3 15
6 MP:0001835 abnormal antigen presentation 2.947E-7 1.528E-5 9.652E-5 9.165E-5 4 74
7 MP:0010766 abnormal NK cell physiology 1.210E-6 5.374E-5 3.396E-4 3.762E-4 4 105
8 MP:0005010 abnormal CD8-positive, alpha beta T cell morphology 1.279E-5 4.862E-4 3.072E-3 3.979E-3 5 427
9 MP:0005638 hemochromatosis 1.407E-5 4.862E-4 3.072E-3 4.376E-3 2 7
10 MP:0000727 absent CD8-positive, alpha-beta T cells 1.994E-4 6.197E-3 3.915E-2
6.201E-2
 2 25
11 MP:0008077 abnormal CD8-positive, alpha-beta T cell number 2.368E-4 6.197E-3 3.915E-2
7.365E-2
 4 400
12 MP:0012765 decreased alpha-beta T cell number 2.391E-4 6.197E-3 3.915E-2
7.436E-2
 4 401
13 MP:0004031 insulitis 3.497E-4 8.249E-3
5.212E-2
1.087E-1
 2 33
14 MP:0008807 increased liver iron level 3.713E-4 8.249E-3
5.212E-2
1.155E-1
 2 34
15 MP:0000708 thymus hyperplasia 4.645E-4 9.512E-3
6.010E-2
1.445E-1
 2 38
16 MP:0004801 increased susceptibility to systemic lupus erythematosus 4.894E-4 9.512E-3
6.010E-2
1.522E-1
 2 39
17 MP:0004803 increased susceptibility to autoimmune diabetes 5.953E-4 1.077E-2
6.805E-2
1.851E-1
 2 43
18 MP:0008738 abnormal liver iron level 6.234E-4 1.077E-2
6.805E-2
1.939E-1
 2 44
19 MP:0004804 decreased susceptibility to autoimmune diabetes 6.814E-4 1.115E-2
7.047E-2
2.119E-1
 2 46
20 MP:0001840 increased level of surface class I molecules 8.691E-4 1.287E-2
8.133E-2
2.703E-1
 1 1
21 MP:0008696 increased interleukin-3 secretion 8.691E-4 1.287E-2
8.133E-2
2.703E-1
 1 1
22 MP:0003944 abnormal T cell subpopulation ratio 1.158E-3 1.566E-2
9.893E-2
3.601E-1
 2 60
23 MP:0013887 abnormal T cell compartment 1.158E-3 1.566E-2
9.893E-2
3.601E-1
 2 60
24 MP:0008079 decreased CD8-positive, alpha-beta T cell number 1.471E-3 1.906E-2
1.204E-1
4.574E-1
 3 281
25 MP:0008350 increased gamma-delta intraepithelial T cell number 1.738E-3 2.162E-2
1.366E-1
5.404E-1
 1 2
26 MP:0001869 pancreas inflammation 1.900E-3 2.272E-2
1.436E-1
5.908E-1
 2 77
27 MP:0012764 increased alpha-beta T cell number 2.062E-3 2.353E-2
1.487E-1
6.414E-1
 3 316
28 MP:0008075 decreased CD4-positive, alpha beta T cell number 2.119E-3 2.353E-2
1.487E-1
6.590E-1
 3 319
29 MP:0000709 enlarged thymus 2.529E-3 2.712E-2
1.713E-1
7.864E-1
 2 89
30 MP:0001828 abnormal T cell activation 3.466E-3 3.375E-2
2.132E-1
1.000E0
 3 379
31 MP:0001837 defective assembly of class I molecules 3.473E-3 3.375E-2
2.132E-1
1.000E0
 1 4
32 MP:0008695 abnormal interleukin-3 secretion 3.473E-3 3.375E-2
2.132E-1
1.000E0
 1 4
33 MP:0008353 increased mature gamma-delta T cell number 4.339E-3 4.089E-2
2.584E-1
1.000E0
 1 5
34 MP:0008811 abnormal brain iron level 5.205E-3 4.496E-2
2.841E-1
1.000E0
 1 6
35 MP:0008401 abnormal CD8 positive, alpha-beta intraepithelial T cell morphology 5.205E-3 4.496E-2
2.841E-1
1.000E0
 1 6
36 MP:0020369 increased intestinal iron level 5.205E-3 4.496E-2
2.841E-1
1.000E0
 1 6
37 MP:0002915 abnormal synaptic depression 5.475E-3 4.602E-2
2.908E-1
1.000E0
 2 132
38 MP:0008740 abnormal intestinal iron level 6.070E-3 4.840E-2
3.058E-1
1.000E0
 1 7
39 MP:0005040 abnormal MHC II cell surface expression on macrophages 6.070E-3 4.840E-2
3.058E-1
1.000E0
 1 7
40 MP:0008073 abnormal CD4-positive, alpha beta T cell number 6.358E-3 4.919E-2
3.108E-1
1.000E0
 3 470
41 MP:0001770 abnormal iron level 6.485E-3 4.919E-2
3.108E-1
1.000E0
 2 144
Show 36 more annotations

6: Domain [Display Chart] 21 input genes in category / 54 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR011162 MHC I/II-like Ag-recog InterPro 8.916E-38 4.815E-36 2.203E-35 4.815E-36 15 38
2 PS00290 IG MHC PROSITE 3.045E-34 8.222E-33 3.762E-32 1.644E-32 15 60
3 PF07654 C1-set Pfam 4.967E-32 8.940E-31 4.090E-30 2.682E-30 14 54
4 IPR003006 Ig/MHC CS InterPro 1.550E-31 1.674E-30 7.660E-30 8.371E-30 14 58
5 IPR003597 Ig C1-set InterPro 1.550E-31 1.674E-30 7.660E-30 8.371E-30 14 58
6 SM00407 IGc1 SMART 6.748E-29 6.073E-28 2.779E-27 3.644E-27 13 56
7 IPR001039 MHC I a a1/a2 InterPro 1.097E-22 7.405E-22 3.388E-21 5.924E-21 9 21
8 PF00129 MHC I Pfam 1.097E-22 7.405E-22 3.388E-21 5.924E-21 9 21
9 3.30.500.10 - Gene3D 4.871E-22 2.630E-21 1.204E-20 2.630E-20 9 24
10 IPR011161 MHC I-like Ag-recog InterPro 4.871E-22 2.630E-21 1.204E-20 2.630E-20 9 24
11 PS50835 IG LIKE PROSITE 6.076E-18 2.983E-17 1.365E-16 3.281E-16 14 492
12 IPR014745 MHC II a/b N InterPro 2.700E-15 1.122E-14 5.132E-14 1.458E-13 6 14
13 3.10.320.10 - Gene3D 2.700E-15 1.122E-14 5.132E-14 1.458E-13 6 14
14 SM00920 MHC II alpha SMART 1.212E-8 4.090E-8 1.872E-7 6.545E-7 3 5
15 IPR032431 C1-set C InterPro 1.212E-8 4.090E-8 1.872E-7 6.545E-7 3 5
16 PF16196 C1-set C Pfam 1.212E-8 4.090E-8 1.872E-7 6.545E-7 3 5
17 PF00993 MHC II alpha Pfam 2.422E-8 6.884E-8 3.150E-7 1.308E-6 3 6
18 PF06623 MHC I C Pfam 2.422E-8 6.884E-8 3.150E-7 1.308E-6 3 6
19 IPR010579 MHC I a C InterPro 2.422E-8 6.884E-8 3.150E-7 1.308E-6 3 6
20 IPR001003 MHC II a N InterPro 4.236E-8 1.144E-7 5.233E-7 2.287E-6 3 7
21 PD000328 MHC II b N ProDom 6.772E-8 1.741E-7 7.968E-7 3.657E-6 3 8
22 SM00921 MHC II beta SMART 1.015E-7 2.284E-7 1.045E-6 5.482E-6 3 9
23 IPR000353 MHC II b N InterPro 1.015E-7 2.284E-7 1.045E-6 5.482E-6 3 9
24 PF00969 MHC II beta Pfam 1.015E-7 2.284E-7 1.045E-6 5.482E-6 3 9
25 IPR015707 B2Microglobulin InterPro 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
26 IPR031092 HFE InterPro 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
27 IPR026569 Ribo L28/L24 InterPro 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
28 PF05391 Lsm interact Pfam 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
29 IPR033520 ERAP1 InterPro 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
30 IPR008669 LSM interact InterPro 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
31 PF00830 Ribosomal L28 Pfam 1.121E-3 1.953E-3 8.934E-3
6.053E-2
 1 1
32 IPR008056 Tapasin InterPro 2.241E-3 3.781E-3 1.730E-2
1.210E-1
 1 2
33 IPR024571 ERAP1-like C dom InterPro 8.934E-3 1.419E-2
6.492E-2
4.824E-1
 1 8
34 PF11838 ERAP1 C Pfam 8.934E-3 1.419E-2
6.492E-2
4.824E-1
 1 8
35 SM00386 HAT SMART 1.116E-2 1.673E-2
7.656E-2
6.024E-1
 1 10
36 IPR003107 HAT InterPro 1.116E-2 1.673E-2
7.656E-2
6.024E-1
 1 10
37 IPR001930 Peptidase M1 InterPro 1.337E-2 1.952E-2
8.929E-2
7.221E-1
 1 12
38 IPR014782 Peptidase M1 N InterPro 1.448E-2 2.005E-2
9.173E-2
7.818E-1
 1 13
39 PF01433 Peptidase M1 Pfam 1.448E-2 2.005E-2
9.173E-2
7.818E-1
 1 13
Show 34 more annotations

7: Pathway [Display Chart] 19 input genes in category / 81 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 83074 Antigen processing and presentation BioSystems: KEGG 6.216E-23 5.035E-21 2.506E-20 5.035E-21 12 77
2 83123 Allograft rejection BioSystems: KEGG 1.745E-21 7.068E-20 3.518E-19 1.414E-19 10 38
3 83124 Graft-versus-host disease BioSystems: KEGG 4.130E-21 1.115E-19 5.551E-19 3.346E-19 10 41
4 83095 Type I diabetes mellitus BioSystems: KEGG 7.055E-21 1.429E-19 7.111E-19 5.714E-19 10 43
5 83121 Autoimmune thyroid disease BioSystems: KEGG 7.127E-20 1.155E-18 5.747E-18 5.773E-18 10 53
6 1269314 Interferon gamma signaling BioSystems: REACTOME 1.788E-19 2.414E-18 1.202E-17 1.448E-17 11 94
7 125138 Viral myocarditis BioSystems: KEGG 2.287E-19 2.647E-18 1.318E-17 1.853E-17 10 59
8 1269311 Interferon Signaling BioSystems: REACTOME 1.054E-15 1.067E-14 5.311E-14 8.535E-14 11 202
9 1269194 Antigen Presentation: Folding, assembly and peptide loading of class I MHC BioSystems: REACTOME 2.598E-15 2.296E-14 1.143E-13 2.104E-13 7 25
10 83069 Cell adhesion molecules (CAMs) BioSystems: KEGG 2.835E-15 2.296E-14 1.143E-13 2.296E-13 10 145
11 153910 Phagosome BioSystems: KEGG 5.245E-15 3.862E-14 1.922E-13 4.248E-13 10 154
12 377873 Herpes simplex infection BioSystems: KEGG 3.383E-14 2.284E-13 1.137E-12 2.741E-12 10 185
13 585562 Epstein-Barr virus infection BioSystems: KEGG 8.651E-14 5.390E-13 2.683E-12 7.008E-12 10 203
14 83079 Natural killer cell mediated cytotoxicity BioSystems: KEGG 1.163E-13 6.731E-13 3.350E-12 9.423E-12 9 133
15 1269201 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell BioSystems: REACTOME 1.428E-13 7.710E-13 3.838E-12 1.156E-11 9 136
16 1269174 Translocation of ZAP-70 to Immunological synapse BioSystems: REACTOME 3.863E-13 1.956E-12 9.734E-12 3.129E-11 6 22
17 373901 HTLV-I infection BioSystems: KEGG 8.906E-13 4.115E-12 2.048E-11 7.213E-11 10 256
18 1269173 Phosphorylation of CD3 and TCR zeta chains BioSystems: REACTOME 9.144E-13 4.115E-12 2.048E-11 7.407E-11 6 25
19 1269182 PD-1 signaling BioSystems: REACTOME 1.188E-12 5.063E-12 2.520E-11 9.620E-11 6 26
20 1269198 Endosomal/Vacuolar pathway BioSystems: REACTOME 3.673E-12 1.458E-11 7.260E-11 2.975E-10 5 12
21 83120 Asthma BioSystems: KEGG 3.781E-12 1.458E-11 7.260E-11 3.063E-10 6 31
22 1269175 Generation of second messenger molecules BioSystems: REACTOME 9.958E-12 3.666E-11 1.825E-10 8.066E-10 6 36
23 128760 Intestinal immune network for IgA production BioSystems: KEGG 7.066E-11 2.489E-10 1.239E-9 5.724E-9 6 49
24 172846 Staphylococcus aureus infection BioSystems: KEGG 1.630E-10 5.503E-10 2.739E-9 1.321E-8 6 56
25 842771 Inflammatory bowel disease (IBD) BioSystems: KEGG 4.114E-10 1.333E-9 6.636E-9 3.333E-8 6 65
26 1269177 Costimulation by the CD28 family BioSystems: REACTOME 8.419E-10 2.526E-9 1.257E-8 6.819E-8 6 73
27 144181 Leishmaniasis BioSystems: KEGG 8.419E-10 2.526E-9 1.257E-8 6.819E-8 6 73
28 1269197 ER-Phagosome pathway BioSystems: REACTOME 2.466E-9 7.134E-9 3.551E-8 1.998E-7 6 87
29 200309 Rheumatoid arthritis BioSystems: KEGG 3.032E-9 8.470E-9 4.216E-8 2.456E-7 6 90
30 1458885 Th1 and Th2 cell differentiation BioSystems: KEGG 3.467E-9 9.360E-9 4.659E-8 2.808E-7 6 92
31 83078 Hematopoietic cell lineage BioSystems: KEGG 4.783E-9 1.250E-8 6.221E-8 3.874E-7 6 97
32 1269200 MHC class II antigen presentation BioSystems: REACTOME 6.883E-9 1.640E-8 8.162E-8 5.575E-7 6 103
33 1269176 Downstream TCR signaling BioSystems: REACTOME 6.883E-9 1.640E-8 8.162E-8 5.575E-7 6 103
34 1269195 Antigen processing-Cross presentation BioSystems: REACTOME 6.883E-9 1.640E-8 8.162E-8 5.575E-7 6 103
35 1469482 Th17 cell differentiation BioSystems: KEGG 8.668E-9 2.006E-8 9.986E-8 7.021E-7 6 107
36 169642 Toxoplasmosis BioSystems: KEGG 1.205E-8 2.712E-8 1.350E-7 9.763E-7 6 113
37 1269172 TCR signaling BioSystems: REACTOME 2.109E-8 4.618E-8 2.299E-7 1.709E-6 6 124
38 83122 Systemic lupus erythematosus BioSystems: KEGG 3.213E-8 6.848E-8 3.409E-7 2.602E-6 6 133
39 217173 Influenza A BioSystems: KEGG 1.542E-7 3.202E-7 1.594E-6 1.249E-5 6 173
40 213780 Tuberculosis BioSystems: KEGG 1.887E-7 3.821E-7 1.902E-6 1.528E-5 6 179
41 1269192 Class I MHC mediated antigen processing & presentation BioSystems: REACTOME 7.981E-7 1.577E-6 7.849E-6 6.465E-5 7 376
42 137922 IL12-mediated signaling events BioSystems: Pathway Interaction Database 1.913E-6 3.690E-6 1.837E-5 1.550E-4 4 61
43 1269312 Interferon alpha/beta signaling BioSystems: REACTOME 3.145E-6 5.925E-6 2.949E-5 2.548E-4 4 69
44 P00053 T cell activation PantherDB 4.636E-6 8.535E-6 4.248E-5 3.755E-4 4 76
45 1269104 Nef mediated downregulation of MHC class I complex cell surface expression BioSystems: REACTOME 9.858E-5 1.736E-4 8.640E-4 7.985E-3 2 10
46 M18928 IL 5 Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 9.858E-5 1.736E-4 8.640E-4 7.985E-3 2 10
47 M1473 B Lymphocyte Cell Surface Molecules MSigDB C2 BIOCARTA (v6.0) 1.204E-4 2.074E-4 1.033E-3 9.750E-3 2 11
48 M7298 Antigen Dependent B Cell Activation MSigDB C2 BIOCARTA (v6.0) 1.443E-4 2.435E-4 1.212E-3 1.169E-2 2 12
49 M10765 Lck and Fyn tyrosine kinases in initiation of TCR Activation MSigDB C2 BIOCARTA (v6.0) 1.704E-4 2.817E-4 1.402E-3 1.380E-2 2 13
50 658418 Viral carcinogenesis BioSystems: KEGG 2.113E-4 3.423E-4 1.704E-3 1.712E-2 4 201
Show 45 more annotations

8: Pubmed [Display Chart] 21 input genes in category / 9993 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19449444 Immunoregulatory effects of HIV-1 Nef protein. Pubmed 1.194E-36 1.193E-32 1.168E-31 1.193E-32 13 32
2 12427289 HIV-1 gp120 modulates the immunological function and expression of accessory and co-stimulatory molecules of monocyte-derived dendritic cells. Pubmed 3.575E-29 1.786E-25 1.748E-24 3.573E-25 10 20
3 8084338 HIV-1 gp41 binding proteins and antibodies to gp41 could inhibit enhancement of human Raji cell MHC class I and II expression by gp41. Pubmed 6.824E-29 2.273E-25 2.225E-24 6.819E-25 10 21
4 19770068 Role of HIV-1 Nef protein for virus replication in vitro. Pubmed 2.212E-28 5.527E-25 5.409E-24 2.211E-24 10 23
5 21778700 HIV-1 Gag-virus-like particles induce natural killer cell immune responses via activation and maturation of dendritic cells. Pubmed 1.809E-25 3.615E-22 3.538E-21 1.807E-21 9 21
6 20012522 Interactions of viral protein U (Vpu) with cellular factors. Pubmed 2.879E-24 4.795E-21 4.693E-20 2.877E-20 9 27
7 11181188 [Two loci HLA haplotypes in celiac children. Linkage imbalance and haplotype frequencies. Comparative study with a control population]. Pubmed 3.956E-23 4.941E-20 4.836E-19 3.953E-19 7 8
8 17170457 Human immunodeficiency virus 1 Nef protein downmodulates the ligands of the activating receptor NKG2D and inhibits natural killer cell-mediated cytotoxicity. Pubmed 3.956E-23 4.941E-20 4.836E-19 3.953E-19 7 8
9 11751963 Native HIV-1 Tat protein targets monocyte-derived dendritic cells and enhances their maturation, function, and antigen-specific T cell responses. Pubmed 3.676E-22 4.081E-19 3.994E-18 3.673E-18 8 21
10 19851445 High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. Pubmed 4.911E-21 4.907E-18 4.803E-17 4.907E-17 11 176
11 21922073 Misdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence. Pubmed 1.421E-20 1.291E-17 1.263E-16 1.420E-16 8 31
12 18846964 [Human leukocyte antigen genes to genetic predisposition in diffuse panbronchiolitis]. Pubmed 8.812E-20 6.290E-17 6.156E-16 8.806E-16 6 7
13 17911430 Genetic control of immune response in carriers of the 8.1 ancestral haplotype: correlation with levels of IgG subclasses: its relevance in the pathogenesis of autoimmune diseases. Pubmed 8.812E-20 6.290E-17 6.156E-16 8.806E-16 6 7
14 15304010 Molecular typing of human leukocyte antigen and related polymorphisms following whole genome amplification. Pubmed 8.812E-20 6.290E-17 6.156E-16 8.806E-16 6 7
15 17106278 Human leukocyte antigen class I and class II allele frequencies and HIV-1 infection associations in a Chinese cohort. Pubmed 3.524E-19 2.071E-16 2.027E-15 3.521E-15 6 8
16 12296785 HLA-A, B, Cw, DRB1, DRB3/4/5, DQB1 in German patients suffering from rapidly progressive periodontitis (RPP) and adult periodontitis (AP). Pubmed 3.524E-19 2.071E-16 2.027E-15 3.521E-15 6 8
17 16405603 Correlation between HLA and pityriasis rosea susceptibility in Brazilian blacks. Pubmed 3.524E-19 2.071E-16 2.027E-15 3.521E-15 6 8
18 22103834 Nef performance in macrophages: the master orchestrator of viral persistence and spread. Pubmed 3.818E-19 2.120E-16 2.075E-15 3.816E-15 7 20
19 22175768 Editorial. Nef: a notorious enigmatic factor in HIV biology. Pubmed 1.703E-18 8.955E-16 8.764E-15 1.701E-14 7 24
20 18672082 Role of HIV-1 Vpu protein for virus spread and pathogenesis. Pubmed 2.364E-18 1.125E-15 1.101E-14 2.362E-14 7 25
21 16091223 HIV accessory proteins and surviving the host cell. Pubmed 2.364E-18 1.125E-15 1.101E-14 2.362E-14 7 25
22 12956878 Roles of HLA-B, HLA-C and HLA-DPA1 incompatibilities in the outcome of unrelated stem-cell transplantation. Pubmed 2.641E-18 1.200E-15 1.174E-14 2.639E-14 6 10
23 12836198 [The HIV nef and the Kaposi-sarcoma-associated virus K3/K5 proteins: "parasites"of the endocytosis pathway]. Pubmed 4.364E-18 1.896E-15 1.856E-14 4.361E-14 7 27
24 22103833 One protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef. Pubmed 5.817E-18 2.422E-15 2.371E-14 5.813E-14 7 28
25 15078178 HIV/SIV escape from immune surveillance: focus on Nef. Pubmed 7.666E-18 3.064E-15 2.999E-14 7.661E-14 7 29
26 19196481 High resolution human leukocyte antigen (HLA) class I and class II allele typing in Mexican mestizo women with sporadic breast cancer: case-control study. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
27 19159415 High-resolution HLA matching in double-umbilical-cord-blood reduced-intensity transplantation in adults. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
28 15307871 HLA disparity determines disease activity through pregnancy in women with inflammatory bowel disease. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
29 19407364 HLA haplotype A33-B58-Cw10 may modulate radiographic development of bamboo spine in Taiwanese patients with primary ankylosing spondylitis. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
30 15051759 Cell surface organization of stress-inducible proteins ULBP and MICA that stimulate human NK cells and T cells via NKG2D. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
31 15323271 HLA alleles and lung cancer in a Turkish population. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
32 17604825 Human leukocyte antigens in undifferentiated spondyloarthritis. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
33 19728333 The prognostic role of classical and nonclassical MHC class I expression in endometrial cancer. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
34 12445319 HLA polymorphism in six ethnic groups from Pakistan. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
35 16267409 Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
36 18381784 Human leukocyte antigen and clinical and demographic characteristics in psoriatic arthritis and psoriasis in Chinese patients. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
37 11543892 Molecular analysis of HLA allelic frequencies and haplotypes in Jordanians and comparison with other related populations. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
38 16609350 Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. Pubmed 3.006E-17 7.904E-15 7.735E-14 3.003E-13 5 5
39 1869305 Interaction of CD4 with HLA class II antigens and HIV gp120. Pubmed 3.771E-17 9.422E-15 9.221E-14 3.769E-13 6 14
40 7512597 HLA class II antigens and the HIV envelope glycoprotein gp120 bind to the same face of CD4. Pubmed 3.771E-17 9.422E-15 9.221E-14 3.769E-13 6 14
41 1967269 HIV-gp120 can block CD4-class II MHC-mediated adhesion. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
42 9079699 The enhanced immune response to the HIV gp160/LAMP chimeric gene product targeted to the lysosome membrane protein trafficking pathway. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
43 3489470 AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
44 10729169 Efficient incorporation of HLA class II onto human immunodeficiency virus type 1 requires envelope glycoprotein packaging. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
45 8168144 Envelope glycoproteins of HIV-1 interfere with T-cell-dependent B cell differentiation: role of CD4-MHC class II interaction in the effector phase of T cell help. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
46 7602119 Endocytosis of endogenously synthesized HIV-1 envelope protein. Mechanism and role in processing for association with class II MHC. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
47 22860026 Strategy for identifying dendritic cell-processed CD4+ T cell epitopes from the HIV gag p24 protein. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
48 8376762 HIV-1 envelope protein is expressed on the surface of infected cells before its processing and presentation to class II-restricted T lymphocytes. Pubmed 6.283E-17 1.308E-14 1.280E-13 6.279E-13 6 15
49 2846691 Inhibition of CD4+ T cell function by the HIV envelope protein, gp120. Pubmed 1.005E-16 1.931E-14 1.890E-13 1.004E-12 6 16
50 17959659 Human immunodeficiency virus type 1 Vpu protein interacts with CD74 and modulates major histocompatibility complex class II presentation. Pubmed 1.005E-16 1.931E-14 1.890E-13 1.004E-12 6 16
Show 45 more annotations

9: Interaction [Display Chart] 21 input genes in category / 634 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:B2M B2M interactions 6.587E-14 3.101E-11 2.180E-10 4.176E-11 7 47
2 int:HLA-A HLA-A interactions 9.782E-14 3.101E-11 2.180E-10 6.201E-11 8 95
3 int:LILRB1 LILRB1 interactions 1.765E-13 3.730E-11 2.623E-10 1.119E-10 5 9
4 int:HLA-B HLA-B interactions 5.477E-12 8.681E-10 6.103E-9 3.473E-9 7 86
5 int:HLA-G HLA-G interactions 1.192E-11 1.260E-9 8.856E-9 7.559E-9 5 18
6 int:TAPBP TAPBP interactions 1.192E-11 1.260E-9 8.856E-9 7.559E-9 5 18
7 int:CD8A CD8A interactions 2.825E-11 2.559E-9 1.799E-8 1.791E-8 5 21
8 int:TAP2 TAP2 interactions 1.357E-10 1.076E-8 7.562E-8 8.605E-8 5 28
9 int:LILRB2 LILRB2 interactions 3.058E-10 2.154E-8 1.514E-7 1.939E-7 4 10
10 int:HLA-C HLA-C interactions 5.635E-10 3.573E-8 2.512E-7 3.573E-7 6 86
11 int:TAP1 TAP1 interactions 1.482E-9 8.541E-8 6.004E-7 9.395E-7 5 44
12 int:HLA-DRB5 HLA-DRB5 interactions 4.429E-9 2.296E-7 1.614E-6 2.808E-6 4 18
13 int:HLA-E HLA-E interactions 4.707E-9 2.296E-7 1.614E-6 2.985E-6 5 55
14 int:MS4A1 MS4A1 interactions 7.001E-9 3.171E-7 2.229E-6 4.439E-6 4 20
15 int:HLA-DRB1 HLA-DRB1 interactions 9.420E-8 3.982E-6 2.799E-5 5.972E-5 4 37
16 int:KLRK1 KLRK1 interactions 1.203E-7 4.766E-6 3.351E-5 7.626E-5 3 9
17 int:SLC39A5 SLC39A5 interactions 2.311E-7 8.620E-6 6.060E-5 1.465E-4 4 46
18 int:ANXA11 ANXA11 interactions 3.252E-7 1.145E-5 8.053E-5 2.062E-4 4 50
19 int:FCGRT FCGRT interactions 6.833E-7 2.280E-5 1.603E-4 4.332E-4 4 60
20 int:CALR CALR interactions 7.956E-7 2.522E-5 1.773E-4 5.044E-4 5 152
21 int:HLA-F HLA-F interactions 1.377E-6 4.157E-5 2.923E-4 8.731E-4 3 19
22 int:RAET1E RAET1E interactions 1.619E-6 4.665E-5 3.280E-4 1.026E-3 3 20
23 int:ULBP3 ULBP3 interactions 1.887E-6 5.202E-5 3.657E-4 1.196E-3 3 21
24 int:PTPRO PTPRO interactions 2.654E-6 7.012E-5 4.929E-4 1.683E-3 4 84
25 int:ATP1B1 ATP1B1 interactions 2.917E-6 7.397E-5 5.200E-4 1.849E-3 4 86
26 int:RAET1G RAET1G interactions 4.018E-6 9.797E-5 6.888E-4 2.547E-3 2 3
27 int:HLA-DQA1 HLA-DQA1 interactions 6.979E-6 1.639E-4 1.152E-3 4.425E-3 3 32
28 int:TNFSF8 TNFSF8 interactions 1.279E-5 2.896E-4 2.036E-3 8.110E-3 3 39
29 int:KLRC4 KLRC4 interactions 2.005E-5 3.972E-4 2.792E-3 1.271E-2 2 6
30 int:CTAG1B CTAG1B interactions 2.005E-5 3.972E-4 2.792E-3 1.271E-2 2 6
31 int:HLA-H HLA-H interactions 2.005E-5 3.972E-4 2.792E-3 1.271E-2 2 6
32 int:HFE HFE interactions 2.005E-5 3.972E-4 2.792E-3 1.271E-2 2 6
33 int:EIF2AK3 EIF2AK3 interactions 2.256E-5 4.334E-4 3.047E-3 1.430E-2 3 47
34 int:HLA-DRA HLA-DRA interactions 2.404E-5 4.483E-4 3.152E-3 1.524E-2 3 48
35 int:KLRD1 KLRD1 interactions 2.804E-5 5.080E-4 3.571E-3 1.778E-2 2 7
36 int:CD1B CD1B interactions 3.244E-5 5.713E-4 4.016E-3 2.057E-2 3 53
37 int:HLA-DMA HLA-DMA interactions 5.997E-5 1.028E-3 7.224E-3 3.802E-2 2 10
38 int:ULBP1 ULBP1 interactions 7.324E-5 1.222E-3 8.590E-3 4.643E-2 2 11
39 int:PKM PKM interactions 9.650E-5 1.569E-3 1.103E-2
6.118E-2
 4 209
40 int:MARCH1 MARCH1 interactions 1.037E-4 1.644E-3 1.156E-2
6.576E-2
 2 13
41 int:SEMA4F SEMA4F interactions 1.394E-4 2.156E-3 1.516E-2
8.839E-2
 2 15
42 int:HLA-DRB3 HLA-DRB3 interactions 1.592E-4 2.404E-3 1.690E-2
1.009E-1
 2 16
43 int:COPB1 COPB1 interactions 2.638E-4 3.889E-3 2.734E-2
1.672E-1
 3 107
44 int:CD74 CD74 interactions 2.776E-4 4.001E-3 2.812E-2
1.760E-1
 2 21
45 int:TCTN2 TCTN2 interactions 2.846E-4 4.009E-3 2.818E-2
1.804E-1
 4 277
46 int:IMPAD1 IMPAD1 interactions 3.641E-4 4.912E-3 3.453E-2
2.309E-1
 2 24
47 int:LRFN3 LRFN3 interactions 3.641E-4 4.912E-3 3.453E-2
2.309E-1
 2 24
48 int:PRXL2A PRXL2A interactions 3.955E-4 5.117E-3 3.598E-2
2.508E-1
 2 25
49 int:ERAP1 ERAP1 interactions 3.955E-4 5.117E-3 3.598E-2
2.508E-1
 2 25
50 int:TRA TRA interactions 4.282E-4 5.323E-3 3.742E-2
2.715E-1
 2 26
Show 45 more annotations

10: Cytoband [Display Chart] 21 input genes in category / 8 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 6p21.3 6p21.3 5.907E-21 4.725E-20 1.284E-19 4.725E-20 12 257
2 6q25 6q25 4.202E-8 1.681E-7 4.568E-7 3.361E-7 3 12
3 15q21-q22.2 15q21-q22.2 6.059E-4 1.616E-3 4.391E-3 4.847E-3 1 1
4 12p13.2-p12.3 12p13.2-p12.3 2.421E-3 4.843E-3 1.316E-2 1.937E-2 1 4
5 12q24.1 12q24.1 9.051E-3 1.448E-2 3.936E-2
7.241E-2
 1 15
6 5q15 5q15 2.456E-2 3.274E-2
8.899E-2
1.964E-1
 1 41
7 6p21.33 6p21.33 3.046E-2 3.481E-2
9.460E-2
2.437E-1
 1 51
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 10 input genes in category / 39 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$IRF Q6 V$IRF Q6 7.617E-4 1.142E-2 4.856E-2 2.970E-2 3 188
2 V$ISRE 01 V$ISRE 01 7.617E-4 1.142E-2 4.856E-2 2.970E-2 3 188
3 V$IRF1 01 V$IRF1 01 9.523E-4 1.142E-2 4.856E-2 3.714E-2 3 203
4 V$IRF1 Q6 V$IRF1 Q6 1.171E-3 1.142E-2 4.856E-2 4.567E-2 3 218
5 V$IRF2 01 V$IRF2 01 4.958E-3 3.867E-2
1.645E-1
1.934E-1
 2 106

12: Gene Family [Display Chart] 18 input genes in category / 9 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 591 Histocompatibility complex|C1-set domain containing genenames.org 3.235E-35 2.912E-34 8.238E-34 2.912E-34 14 42
2 588 Histocompatibility complex|C1-set domain containing genenames.org 9.803E-23 4.411E-22 1.248E-21 8.823E-22 10 44
3 621 CD molecules|Killer cell lectin like receptors|C-type lectin domain containing genenames.org 1.181E-2 3.543E-2
1.002E-1
1.063E-1
 1 12
4 104 Aminopeptidases genenames.org 1.767E-2 3.975E-2
1.125E-1
1.590E-1
 1 18

13: Coexpression [Display Chart] 21 input genes in category / 1869 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20460173-ImmPortAntigenProcessingandPresentation Human Immune Kong10 148genes ImmPort AntigenProcessingandPresentation GeneSigDB 2.073E-32 3.874E-29 3.142E-28 3.874E-29 16 138
2 M11428 Inflammatory cytokines, chemokines and their cognate receptors up-regulated in THP-1 cells (monocyte) after treatment with PSMD4 [GeneID=5710]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.764E-20 1.648E-17 1.337E-16 3.296E-17 10 73
3 20460173-ImmPortNaturalKillerCellCytotoxicity Human Immune Kong10 135genes ImmPort NaturalKillerCellCytotoxicity GeneSigDB 1.184E-13 5.581E-11 4.527E-10 2.213E-10 8 126
4 M17363 Immune response genes up-regulated in zenograft tumors formed by SNU-601 cells (gastric cancer) made to express LRRC3B [GeneID=116135]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.493E-13 5.581E-11 4.527E-10 2.791E-10 6 30
5 18757430-SuppTable3 Human StemCell Kim08 30genes GeneSigDB 1.493E-13 5.581E-11 4.527E-10 2.791E-10 6 30
6 M4551 Genes up-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by IFNG [GeneID=3458]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.829E-13 1.193E-10 9.675E-10 7.157E-10 7 77
7 M5913 Genes up-regulated in response to IFNG [GeneID=3458]. MSigDB H: Hallmark Gene Sets (v6.0) 5.006E-12 1.337E-9 1.084E-8 9.356E-9 8 200
8 18245496-SuppTable3 Human Prostate Wallace08 86genes GeneSigDB 2.037E-11 4.759E-9 3.860E-8 3.807E-8 6 65
9 18245496-SuppTable2 Human Prostate Wallace08 489genes GeneSigDB 2.578E-11 5.354E-9 4.343E-8 4.819E-8 9 392
10 15833844-Table1S Human Esophagus Kimchi05 213genes GeneSigDB 1.182E-10 2.210E-8 1.792E-7 2.210E-7 7 172
11 18487511-Table1 Human StemCell Singleton08 40genes GeneSigDB 1.364E-10 2.318E-8 1.880E-7 2.550E-7 5 36
12 18922855-Table1 Human StemCell Kuttruff08 108genes GeneSigDB 2.712E-10 4.223E-8 3.425E-7 5.068E-7 6 99
13 M11620 Genes induced in the liver during hepatitis B (HBV) viral clearance in chimpanzees. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.063E-10 4.245E-8 3.443E-7 5.726E-7 6 101
14 M9576 Genes down-regulated in T reg: peripheral lymph nodes versus thymic CD24 int [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 3.407E-10 4.245E-8 3.443E-7 6.367E-7 7 200
15 M9586 Genes down-regulated in thymic T reg: CD24 high [GeneID=100133941] versus CD24 int [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 3.407E-10 4.245E-8 3.443E-7 6.367E-7 7 200
16 M8341 Antigen processing and presentation genes down-regulated in JY cells (B lymphocytes) treated with trichostatin A (TSA) [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.850E-10 8.001E-8 6.490E-7 1.280E-6 5 49
17 17894856-SuppList2 Human Breast Yu07 400genes GeneSigDB 1.661E-9 1.827E-7 1.481E-6 3.105E-6 7 251
18 19139017-Table3 Human Colon Protiva09 31genes GeneSigDB 4.390E-9 4.559E-7 3.697E-6 8.205E-6 4 23
19 18487511-TableS2 Human StemCell Singleton08 47genes GeneSigDB 1.353E-8 1.331E-6 1.080E-5 2.529E-5 4 30
20 M7545 Genes up-regulated in untreated double positive thymocytes: ELK1 [GeneID=2002] knockout versus ELK1 and ELK4 [GeneID=2002;2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.775E-8 1.409E-6 1.143E-5 3.318E-5 6 198
21 M9568 Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=10219] knockout versus BCL2L11 [GeneID=10018] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.829E-8 1.409E-6 1.143E-5 3.419E-5 6 199
22 M5950 Genes up-regulated during transplant rejection. MSigDB H: Hallmark Gene Sets (v6.0) 1.885E-8 1.409E-6 1.143E-5 3.523E-5 6 200
23 M9570 Genes down-regulated in T reg from: peripheral lymph nodes versus thymic precursors. MSigDB C7: Immunologic Signatures (v6.0) 1.885E-8 1.409E-6 1.143E-5 3.523E-5 6 200
24 M8080 Genes up-regulated in lymph node CD4 [GeneID=920] T cells: scurfy (non-functional form of FOXP3 [GeneID=50943]) versus scurfy and IL2 [GeneID=3558] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.885E-8 1.409E-6 1.143E-5 3.523E-5 6 200
25 M9580 Genes down-regulated in T reg: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 1.885E-8 1.409E-6 1.143E-5 3.523E-5 6 200
26 16597596-TableS3-1 Human Leukemia Wilson06 50genes DifferentialClusterA2 GeneSigDB 9.506E-8 6.834E-6 5.543E-5 1.777E-4 4 48
27 15026349-Table3a Human Lung Carson04 56genes GeneSigDB 1.219E-7 8.135E-6 6.598E-5 2.278E-4 4 51
28 14744790-Table1a Human Brain DiarraMehrpour04 53genes GeneSigDB 1.219E-7 8.135E-6 6.598E-5 2.278E-4 4 51
29 M5389 Genes whose expression increases with age in normal kidney. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.557E-7 1.004E-5 8.140E-5 2.910E-4 7 486
30 20067540-Table4 Human UmbilicalCordBloodCells Miyagawa09 58genes GeneSigDB 1.659E-7 1.034E-5 8.385E-5 3.101E-4 4 55
31 M10319 Genes up-regulated in prostate cancer samples from African-American patients compared to those from the European-American patients. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.002E-7 1.204E-5 9.762E-5 3.742E-4 6 298
32 M1887 Genes up-regulated in gastric mucosal tissue of mice on 2% cholesterol [PubChem=5997] diet and infected with H. pylori vs those infected with H. pylori while on 0% cholesterol diet. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.061E-7 1.204E-5 9.762E-5 3.851E-4 4 58
33 M12139 Genes down-regulated in acute promyelocytic leukemia (APL) patients with mutated FLT3 [GeneID=2322]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.346E-7 2.461E-5 1.996E-4 8.123E-4 3 17
34 M6150 Genes down-regulated in monocyte-derived macrophages: untreated versus stimulated by interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 7.001E-7 3.805E-5 3.086E-4 1.308E-3 5 193
35 M6129 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (48h) versus IL4 [GeneID=3565] (48h). MSigDB C7: Immunologic Signatures (v6.0) 7.366E-7 3.805E-5 3.086E-4 1.377E-3 5 195
36 M9537 Genes up-regulated in skin: wildtype versus IL1R1 [GeneID=3554] knockout. MSigDB C7: Immunologic Signatures (v6.0) 8.143E-7 3.805E-5 3.086E-4 1.522E-3 5 199
37 M5142 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection. MSigDB C7: Immunologic Signatures (v6.0) 8.143E-7 3.805E-5 3.086E-4 1.522E-3 5 199
38 M9572 Genes up-regulated in cells from peripheral lymph nodes: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 8.347E-7 3.805E-5 3.086E-4 1.560E-3 5 200
39 M8524 Genes down-regulated in macrophages: resting differentiated versus alternatively activated M2. MSigDB C7: Immunologic Signatures (v6.0) 8.347E-7 3.805E-5 3.086E-4 1.560E-3 5 200
40 M9038 Genes up-regulated in macrophages with knockout of HDAC3 [GeneID=8841]: heterozygous versus homozygous. MSigDB C7: Immunologic Signatures (v6.0) 8.347E-7 3.805E-5 3.086E-4 1.560E-3 5 200
41 M3635 Genes down-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after stimulation with antigen-B7-1. MSigDB C7: Immunologic Signatures (v6.0) 8.347E-7 3.805E-5 3.086E-4 1.560E-3 5 200
42 M17466 Genes up-regulated in five primary endothelial cell types (lung, aortic, iliac, dermal, and colon) by TNF [GeneID=7124]. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.795E-7 3.914E-5 3.174E-4 1.644E-3 4 83
43 M2259 Partial list of genes up-regulated in the kidney of GLIS2 [GeneID=84662] knockout mice compared to the wild type. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.229E-7 4.011E-5 3.254E-4 1.725E-3 4 84
44 M1578 Genes down-regulated in freshly isolated CD31- [GeneID=5175] (stromal stem cells from adipose tissue) versus the CD31+ (non-stem) counterparts. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.220E-6 5.181E-5 4.202E-4 2.280E-3 5 216
45 18321301-Table2b Human Stomach Galamb08 36genes GeneSigDB 1.653E-6 6.716E-5 5.447E-4 3.090E-3 3 26
46 18398031-Fig1 Human Ovarian LePage08 34genes GeneSigDB 1.653E-6 6.716E-5 5.447E-4 3.090E-3 3 26
47 17483311-SuppTable3 Human Brain Beier07 117genes GeneSigDB 1.785E-6 7.097E-5 5.756E-4 3.336E-3 4 99
48 M5487 Hepatic graft versus host disease (GVHD), day 7: up-regulated in allogeneic vs syngeneic bone marrow transplant. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.435E-6 9.482E-5 7.691E-4 4.551E-3 4 107
49 17483311-SuppTable1 Human Brain Beier07 383genes GeneSigDB 3.576E-6 1.364E-4 1.106E-3 6.684E-3 5 269
50 15958054-Table3 Human Stomach Yanagihara05 60genes GeneSigDB 4.139E-6 1.547E-4 1.255E-3 7.737E-3 3 35
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 20 input genes in category / 2132 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC2/Kidney Tumour Wilms MNP RCC2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC2/Kidney Tumour Wilms MNP RCC2 Adult, Development, and Cancer types 7.497E-18 1.598E-14 1.317E-13 1.598E-14 9 76
2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Tumour RCC Nephrogenesis Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Tumour RCC Nephrogenesis Adult, Development, and Cancer types 7.885E-17 7.721E-14 6.364E-13 1.681E-13 7 25
3 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Tumour PapRCC Junk Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Tumour PapRCC Junk Adult, Development, and Cancer types 1.086E-16 7.721E-14 6.364E-13 2.316E-13 9 101
4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter epithelium/Kidney Tumour PapRCC Ureter epithelium Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter epithelium/Kidney Tumour PapRCC Ureter epithelium Adult, Development, and Cancer types 1.561E-16 7.932E-14 6.538E-13 3.327E-13 9 105
5 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC2/Kidney Tumour RCC MNP RCC2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC2/Kidney Tumour RCC MNP RCC2 Adult, Development, and Cancer types 1.860E-16 7.932E-14 6.538E-13 3.966E-13 9 107
6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour PapRCC NK cell/Kidney Tumour PapRCC NK17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour PapRCC NK cell/Kidney Tumour PapRCC NK17 Adult, Development, and Cancer types 2.713E-16 9.639E-14 7.945E-13 5.784E-13 10 186
7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2/Kidney Tumour RCC MNP2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2/Kidney Tumour RCC MNP2 Adult, Development, and Cancer types 6.285E-16 1.914E-13 1.578E-12 1.340E-12 9 122
8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Th cell/Kidney Tumour PapRCC Th cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Th cell/Kidney Tumour PapRCC Th cell Adult, Development, and Cancer types 1.213E-15 3.233E-13 2.665E-12 2.587E-12 9 131
9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal VHL RCC R U/Kidney Normal VHL RCC R7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal VHL RCC R U/Kidney Normal VHL RCC R7 Adult, Development, and Cancer types 6.224E-15 1.474E-12 1.215E-11 1.327E-11 7 44
10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney N-U/Kidney NephrogenicRest Wilms N-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney N-U/Kidney NephrogenicRest Wilms N-U Adult, Development, and Cancer types 8.812E-15 1.853E-12 1.528E-11 1.879E-11 8 92
11 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour PapRCC EN-A Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour PapRCC EN-A Adult, Development, and Cancer types 9.562E-15 1.853E-12 1.528E-11 2.039E-11 9 164
12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour PapRCC PT-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour PapRCC PT-U Adult, Development, and Cancer types 1.615E-14 2.870E-12 2.365E-11 3.444E-11 8 99
13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour Wilms PT-U/Kidney Tumour Wilms PT20 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour Wilms PT-U/Kidney Tumour Wilms PT20 Adult, Development, and Cancer types 1.920E-14 3.149E-12 2.596E-11 4.094E-11 9 177
14 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Normal VHL RCC Nephrogenesis/Kidney Normal VHL RCC F7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Normal VHL RCC Nephrogenesis/Kidney Normal VHL RCC F7 Adult, Development, and Cancer types 2.164E-14 3.295E-12 2.716E-11 4.613E-11 7 52
15 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney B cell/Kidney Normal-Medulla Wilms B cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney B cell/Kidney Normal-Medulla Wilms B cell Adult, Development, and Cancer types 2.874E-14 4.085E-12 3.367E-11 6.128E-11 9 185
16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2-like/Kidney Tumour Wilms MNP2-like Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2-like/Kidney Tumour Wilms MNP2-like Adult, Development, and Cancer types 3.665E-14 4.884E-12 4.025E-11 7.814E-11 9 190
17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour RCC PT-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour RCC PT-U Adult, Development, and Cancer types 5.878E-14 7.371E-12 6.075E-11 1.253E-10 6 26
18 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour PapRCC R U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour PapRCC R U Adult, Development, and Cancer types 1.026E-13 1.215E-11 1.002E-10 2.187E-10 8 124
19 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2-like Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2-like Adult, Development, and Cancer types 1.118E-13 1.255E-11 1.034E-10 2.384E-10 7 65
20 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour RCC U U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour RCC U U Adult, Development, and Cancer types 1.211E-13 1.291E-11 1.064E-10 2.581E-10 6 29
21 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Wilms tumour/Kidney Tumour RCC Wilms tumour Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Wilms tumour/Kidney Tumour RCC Wilms tumour Adult, Development, and Cancer types 2.962E-13 3.008E-11 2.479E-10 6.316E-10 5 12
22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Cortex Wilms U U/Kidney Normal-Cortex Wilms U9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Cortex Wilms U U/Kidney Normal-Cortex Wilms U9 Adult, Development, and Cancer types 6.053E-13 5.866E-11 4.835E-10 1.291E-9 7 82
23 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal VHL RCC Renal cell carcinoma/Kidney Normal VHL RCC T7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal VHL RCC Renal cell carcinoma/Kidney Normal VHL RCC T7 Adult, Development, and Cancer types 6.608E-13 6.125E-11 5.048E-10 1.409E-9 7 83
24 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2 Adult, Development, and Cancer types 7.760E-13 6.894E-11 5.682E-10 1.654E-9 8 159
25 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter epithelium/Kidney Normal RCC Ureter epithelium/Kidney Normal RCC U4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter epithelium/Kidney Normal RCC Ureter epithelium/Kidney Normal RCC U4 Adult, Development, and Cancer types 8.270E-13 7.052E-11 5.813E-10 1.763E-9 6 39
26 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour RCC EN-A Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour RCC EN-A Adult, Development, and Cancer types 9.724E-13 7.973E-11 6.572E-10 2.073E-9 6 40
27 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC2 Adult, Development, and Cancer types 1.536E-12 1.213E-10 9.998E-10 3.275E-9 8 173
28 Human Cell Atlas Human Cell Atlas B cell B cell Subtype Follicular B cell Top 200 Genes Human Cell Atlas Human Cell Atlas B cell B cell Subtype Follicular B cell Top 200 Genes 2.215E-12 1.563E-10 1.289E-9 4.723E-9 9 299
29 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour RCC NK cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour RCC NK cell Adult, Development, and Cancer types 2.308E-12 1.563E-10 1.289E-9 4.920E-9 5 17
30 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Tumour PapRCC Endothelium Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Tumour PapRCC Endothelium Adult, Development, and Cancer types 2.349E-12 1.563E-10 1.289E-9 5.009E-9 7 99
31 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour Wilms EN-A/Kidney Tumour Wilms EN4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour Wilms EN-A/Kidney Tumour Wilms EN4 Adult, Development, and Cancer types 2.418E-12 1.563E-10 1.289E-9 5.156E-9 8 183
32 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Tumour RCC Nephrogenesis/Kidney Tumour RCC F7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Tumour RCC Nephrogenesis/Kidney Tumour RCC F7 Adult, Development, and Cancer types 2.527E-12 1.563E-10 1.289E-9 5.388E-9 8 184
33 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney T regulatory/Kidney Tumour VHL RCC T regulatory Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney T regulatory/Kidney Tumour VHL RCC T regulatory Adult, Development, and Cancer types 2.560E-12 1.563E-10 1.289E-9 5.457E-9 4 5
34 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour RCC PT-U/Kidney Tumour RCC PT7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour RCC PT-U/Kidney Tumour RCC PT7 Adult, Development, and Cancer types 2.640E-12 1.563E-10 1.289E-9 5.628E-9 8 185
35 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R7 Adult, Development, and Cancer types 2.640E-12 1.563E-10 1.289E-9 5.628E-9 8 185
36 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour RCC U U/Kidney Tumour RCC U7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour RCC U U/Kidney Tumour RCC U7 Adult, Development, and Cancer types 2.640E-12 1.563E-10 1.289E-9 5.628E-9 8 185
37 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour RCC NK cell/Kidney Tumour RCC NK7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour RCC NK cell/Kidney Tumour RCC NK7 Adult, Development, and Cancer types 2.757E-12 1.589E-10 1.309E-9 5.878E-9 8 186
38 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP PapRCC/Kidney Tumour PapRCC MNP PapRCC Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP PapRCC/Kidney Tumour PapRCC MNP PapRCC Adult, Development, and Cancer types 2.910E-12 1.633E-10 1.346E-9 6.204E-9 7 102
39 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal VHL RCC PT-U/Kidney Normal VHL RCC PT7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal VHL RCC PT-U/Kidney Normal VHL RCC PT7 Adult, Development, and Cancer types 3.095E-12 1.692E-10 1.395E-9 6.599E-9 6 48
40 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour VHL RCC PT-U/Kidney Tumour VHL RCC PT7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour VHL RCC PT-U/Kidney Tumour VHL RCC PT7 Adult, Development, and Cancer types 3.414E-12 1.820E-10 1.500E-9 7.280E-9 8 191
41 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP PapRCC/Kidney Tumour VHL RCC MNP PapRCC Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP PapRCC/Kidney Tumour VHL RCC MNP PapRCC Adult, Development, and Cancer types 3.561E-12 1.852E-10 1.526E-9 7.592E-9 8 192
42 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour Wilms U U/Kidney Tumour Wilms U7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour Wilms U U/Kidney Tumour Wilms U7 Adult, Development, and Cancer types 3.871E-12 1.965E-10 1.620E-9 8.253E-9 8 194
43 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Tumour RCC IF-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Tumour RCC IF-U Adult, Development, and Cancer types 4.332E-12 2.075E-10 1.710E-9 9.236E-9 5 19
44 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U Adult, Development, and Cancer types 4.332E-12 2.075E-10 1.710E-9 9.236E-9 5 19
45 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal Wilms Fetus other/Kidney Normal Wilms F9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal Wilms Fetus other/Kidney Normal Wilms F9 Adult, Development, and Cancer types 4.380E-12 2.075E-10 1.710E-9 9.338E-9 7 108
46 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter epithelium/Kidney Tumour PapRCC Ureter epithelium/Kidney Tumour PapRCC U4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter epithelium/Kidney Tumour PapRCC Ureter epithelium/Kidney Tumour PapRCC U4 Adult, Development, and Cancer types 5.773E-12 2.675E-10 2.205E-9 1.231E-8 5 20
47 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Normal cell/Kidney Tumour RCC Normal cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Normal cell/Kidney Tumour RCC Normal cell Adult, Development, and Cancer types 7.572E-12 3.273E-10 2.697E-9 1.614E-8 5 21
48 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal-Medulla Wilms Fetus other/Kidney Normal-Medulla Wilms F9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal-Medulla Wilms Fetus other/Kidney Normal-Medulla Wilms F9 Adult, Development, and Cancer types 7.675E-12 3.273E-10 2.697E-9 1.636E-8 4 6
49 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-U Adult, Development, and Cancer types 7.675E-12 3.273E-10 2.697E-9 1.636E-8 4 6
50 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-E Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-E Adult, Development, and Cancer types 7.675E-12 3.273E-10 2.697E-9 1.636E-8 4 6
Show 45 more annotations

15: Computational [Display Chart] 17 input genes in category / 96 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M11830 MODULE 143 Genes in the cancer module 143. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.852E-20 2.738E-18 1.409E-17 2.738E-18 8 14
2 M19264 MODULE 293 Genes in the cancer module 293. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.548E-18 3.623E-16 1.865E-15 7.246E-16 7 12
3 M1653 MODULE 223 Immune (defense) response. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.875E-11 9.199E-10 4.735E-9 2.760E-9 8 142
4 M5267 GNF2 HLA-C Neighborhood of HLA-C MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.017E-11 1.731E-9 8.911E-9 8.657E-9 6 47
5 M7957 GNF2 PTPN6 Neighborhood of PTPN6 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.017E-11 1.731E-9 8.911E-9 8.657E-9 6 47
6 M17909 GNF2 CD53 Neighborhood of CD53 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.364E-10 5.382E-9 2.770E-8 3.229E-8 6 58
7 M688 MODULE 27 Genes in the cancer module 27. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.483E-9 2.033E-8 1.047E-7 1.423E-7 9 355
8 M8633 GNF2 STAT6 Neighborhood of STAT6 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.265E-9 2.718E-8 1.399E-7 2.174E-7 6 79
9 M15983 MODULE 46 Genes in the cancer module 46. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.718E-9 3.901E-8 2.008E-7 3.570E-7 9 394
10 M12401 MODULE 75 Immune response. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.064E-9 3.901E-8 2.008E-7 3.901E-7 9 398
11 M9268 GNF2 INPP5D Neighborhood of INPP5D MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.763E-9 5.902E-8 3.038E-7 6.492E-7 5 43
12 M909 GNF2 CD48 Neighborhood of CD48 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.967E-7 1.574E-6 8.099E-6 1.888E-5 4 32
13 M786 MODULE 345 Immune response and Ag processing and presentation. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.642E-6 1.212E-5 6.240E-5 1.576E-4 5 127
14 M13121 MODULE 171 Genes in the cancer module 171. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.566E-6 1.642E-5 8.451E-5 2.463E-4 5 139
15 M4595 MODULE 436 Genes in the cancer module 436. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.566E-6 1.642E-5 8.451E-5 2.463E-4 5 139
16 M15369 GNF2 PTPRC Neighborhood of PTPRC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.291E-6 2.575E-5 1.325E-4 4.120E-4 4 68
17 M17314 GNF2 VAV1 Neighborhood of VAV1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.784E-5 1.572E-4 8.091E-4 2.673E-3 3 36
18 M8807 MODULE 208 Genes in the cancer module 208. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.813E-5 2.567E-4 1.321E-3 4.620E-3 4 125
19 M782 GNF2 CASP4 Neighborhood of CASP4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.291E-4 3.684E-3 1.896E-2
6.999E-2
 2 24
20 M11485 GNF2 LYN Neighborhood of LYN MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.245E-4 4.437E-3 2.284E-2
8.875E-2
 2 27
21 M19614 MODULE 292 Genes in the cancer module 292. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.470E-3 6.722E-3 3.460E-2
1.412E-1
 3 137
22 M7315 MODULE 119 Genes in the cancer module 119. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.697E-3 7.405E-3 3.811E-2
1.629E-1
 3 144
23 M9200 GNF2 SELL Neighborhood of SELL MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.791E-3 1.165E-2
5.996E-2
2.679E-1
 2 47
Show 18 more annotations

16: MicroRNA [Display Chart] 21 input genes in category / 544 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 9.964E-8 5.421E-5 3.728E-4 5.421E-5 5 403
2 hsa-miR-4524a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.027E-6 5.514E-4 3.792E-3 1.103E-3 4 316
3 hsa-miR-152-3p:Functional MTI Functional MTI miRTarbase 1.326E-5 2.405E-3 1.654E-2 7.215E-3 3 158
4 hsa-miR-148a-3p:Functional MTI Functional MTI miRTarbase 3.232E-5 4.396E-3 3.023E-2 1.758E-2 3 213
5 hsa-miR-623:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.665E-5 4.592E-3 3.158E-2 2.538E-2 3 241
6 hsa-miR-5006-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.776E-5 4.592E-3 3.158E-2 3.142E-2 3 259
7 hsa-miR-4755-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.909E-5 4.592E-3 3.158E-2 3.214E-2 3 261
8 hsa-miR-4537:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.011E-4 6.286E-3 4.323E-2
5.501E-2
 3 313
9 hsa-miR-6832-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.040E-4 6.286E-3 4.323E-2
5.658E-2
 3 316
10 hsa-miR-211-5p:Functional MTI Functional MTI miRTarbase 1.225E-4 6.662E-3 4.581E-2
6.662E-2
 3 334
11 hsa-miR-6822-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.032E-4 8.529E-3
5.866E-2
1.105E-1
 2 72
12 hsa-miR-6750-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.032E-4 8.529E-3
5.866E-2
1.105E-1
 2 72
13 hsa-miR-204-5p:Functional MTI Functional MTI miRTarbase 2.066E-4 8.529E-3
5.866E-2
1.124E-1
 3 399
14 hsa-miR-8060:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.324E-4 8.529E-3
5.866E-2
1.264E-1
 2 77
15 hsa-miR-383-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.401E-4 8.529E-3
5.866E-2
1.306E-1
 3 420
16 hsa-miR-4660:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.509E-4 8.529E-3
5.866E-2
1.365E-1
 2 80
17 hsa-miR-6854-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.700E-4 8.633E-3
5.937E-2
1.469E-1
 2 83
18 hsa-miR-548ao-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.035E-4 8.633E-3
5.937E-2
1.651E-1
 2 88
19 hsa-miR-4670-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.104E-4 8.633E-3
5.937E-2
1.689E-1
 2 89
20 hsa-miR-548ax:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.174E-4 8.633E-3
5.937E-2
1.727E-1
 2 90
21 hsa-miR-4263:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.462E-4 8.926E-3
6.139E-2
1.883E-1
 2 94
22 hsa-miR-4327:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.610E-4 8.926E-3
6.139E-2
1.964E-1
 2 96
23 hsa-miR-3147:mirSVR highEffct hsa-miR-3147:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.880E-4 9.176E-3
6.310E-2
2.110E-1
 3 495
24 hsa-miR-139-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.316E-4 9.570E-3
6.581E-2
2.348E-1
 2 105
25 hsa-miR-6810-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.398E-4 9.570E-3
6.581E-2
2.392E-1
 2 106
26 hsa-miR-4496:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.536E-4 1.149E-2
7.899E-2
3.011E-1
 2 119
27 hsa-miR-5694:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.817E-4 1.149E-2
7.899E-2
3.164E-1
 2 122
28 hsa-miR-330-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.912E-4 1.149E-2
7.899E-2
3.216E-1
 2 123
29 hsa-miR-151-5p:mirSVR highEffct hsa-miR-151-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.599E-4 1.238E-2
8.512E-2
3.590E-1
 2 130
30 hsa-miR-141-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.217E-4 1.299E-2
8.936E-2
3.926E-1
 2 136
31 hsa-miR-326:Functional MTI Functional MTI miRTarbase 7.429E-4 1.299E-2
8.936E-2
4.041E-1
 2 138
32 hsa-miR-2392:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.644E-4 1.299E-2
8.936E-2
4.158E-1
 2 140
33 hsa-miR-574-3p:mirSVR highEffct hsa-miR-574-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.194E-4 1.351E-2
9.290E-2
4.458E-1
 2 145
34 hsa-miR-3197:mirSVR highEffct hsa-miR-3197:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.534E-4 1.365E-2
9.390E-2
4.642E-1
 2 148
35 hsa-miR-5692c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.175E-3 1.776E-2
1.221E-1
6.394E-1
 2 174
36 hsa-miR-5692b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.175E-3 1.776E-2
1.221E-1
6.394E-1
 2 174
37 hsa-miR-767-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.355E-3 1.992E-2
1.370E-1
7.371E-1
 2 187
38 hsa-miR-1306-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.532E-3 2.193E-2
1.508E-1
8.333E-1
 2 199
39 hsa-miR-1250-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.655E-3 2.309E-2
1.588E-1
9.005E-1
 2 207
40 hsa-miR-3714:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.916E-3 2.565E-2
1.764E-1
1.000E0
 2 223
41 hsa-miR-31-5p:Functional MTI Functional MTI miRTarbase 1.933E-3 2.565E-2
1.764E-1
1.000E0
 2 224
42 hsa-miR-5690:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.985E-3 2.571E-2
1.768E-1
1.000E0
 2 227
43 hsa-miR-1249-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.870E-3 3.625E-2
2.493E-1
1.000E0
 2 274
44 hsa-miR-6797-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.932E-3 3.625E-2
2.493E-1
1.000E0
 2 277
45 hsa-miR-5692a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.185E-3 3.850E-2
2.648E-1
1.000E0
 2 289
46 hsa-miR-1911:mirSVR highEffct hsa-miR-1911:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.294E-3 3.895E-2
2.679E-1
1.000E0
 2 294
47 hsa-miR-627-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.606E-3 4.174E-2
2.871E-1
1.000E0
 2 308
48 hsa-miR-6817-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.957E-3 4.331E-2
2.978E-1
1.000E0
 2 323
49 hsa-miR-3672:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.980E-3 4.331E-2
2.978E-1
1.000E0
 2 324
50 hsa-miR-6864-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.980E-3 4.331E-2
2.978E-1
1.000E0
 2 324
Show 45 more annotations

17: Drug [Display Chart] 21 input genes in category / 4367 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000000630 AC1Q6DJO Stitch 1.082E-14 4.724E-11 4.232E-10 4.724E-11 8 93
2 CID005288910 H type 2 Stitch 1.693E-13 2.873E-10 2.574E-9 7.393E-10 8 130
3 CID005326972 DB04680 Stitch 1.973E-13 2.873E-10 2.574E-9 8.618E-10 9 225
4 CID005326974 AC1NS1F1 Stitch 3.300E-12 3.602E-9 3.227E-8 1.441E-8 6 48
5 CID000015325 DNTB Stitch 1.028E-11 7.877E-9 7.057E-8 4.491E-8 8 216
6 CID000010908 tert-butyl acetate Stitch 1.082E-11 7.877E-9 7.057E-8 4.726E-8 6 58
7 CID000005316 sodium sulbactam Stitch 1.457E-9 9.089E-7 8.143E-6 6.362E-6 5 56
8 CID000657106 1xgj Stitch 3.948E-9 2.155E-6 1.931E-5 1.724E-5 5 68
9 ctd:D010165 Palladium CTD 2.339E-8 1.021E-5 9.150E-5 1.021E-4 3 7
10 ctd:C473384 lumiracoxib CTD 2.339E-8 1.021E-5 9.150E-5 1.021E-4 3 7
11 CID000292661 2,4,6-triaminoquinazoline Stitch 6.167E-8 2.448E-5 2.193E-4 2.693E-4 5 117
12 CID000012332 hexanamide Stitch 7.002E-8 2.548E-5 2.283E-4 3.058E-4 5 120
13 CID000250653 4 Mb Stitch 8.004E-8 2.574E-5 2.306E-4 3.495E-4 3 10
14 CID000127242 3'-desamino-3'-dimethylformamidine rubomycin Stitch 8.253E-8 2.574E-5 2.306E-4 3.604E-4 5 124
15 CID000125486 TISCH Stitch 1.283E-7 3.734E-5 3.346E-4 5.602E-4 4 51
16 CID006857661 ONNO Stitch 1.466E-7 4.000E-5 3.584E-4 6.400E-4 3 12
17 CID000003178 AC1L1FCN Stitch 3.026E-7 7.773E-5 6.964E-4 1.321E-3 3 15
18 CID006398604 Ru-pyridocarbazole-2 Stitch 4.138E-7 1.004E-4 8.994E-4 1.807E-3 4 68
19 CID004636205 AC1NE3ZI Stitch 4.390E-7 1.009E-4 9.040E-4 1.917E-3 4 69
20 CID006450878 Etiocobalamin Stitch 4.859E-7 1.061E-4 9.506E-4 2.122E-3 5 177
21 CID000008391 2-nitro-p-cresol Stitch 6.488E-7 1.349E-4 1.209E-3 2.833E-3 4 76
22 CID005037551 NSC603722 Stitch 7.205E-7 1.430E-4 1.281E-3 3.146E-3 4 78
23 CID000644309 AC1LD8Z3 Stitch 1.068E-6 2.027E-4 1.816E-3 4.662E-3 4 86
24 CID000002416 BMS-186282 Stitch 1.592E-6 2.896E-4 2.595E-3 6.951E-3 4 95
25 CID003474204 VAI2 Stitch 1.730E-6 3.023E-4 2.708E-3 7.557E-3 4 97
26 ctd:D002434 Cefadroxil CTD 2.414E-6 4.054E-4 3.632E-3 1.054E-2 2 3
27 CID000447261 PA-J Stitch 4.825E-6 7.804E-4 6.992E-3 2.107E-2 2 4
28 ctd:C030583 ceric oxide CTD 5.992E-6 9.345E-4 8.373E-3 2.617E-2 3 39
29 CID000023830 HEPES Stitch 6.652E-6 1.002E-3 8.975E-3 2.905E-2 4 136
30 ctd:C111827 brinzolamide CTD 8.037E-6 1.097E-3 9.827E-3 3.510E-2 2 5
31 ctd:C038192 iopromide CTD 8.037E-6 1.097E-3 9.827E-3 3.510E-2 2 5
32 CID000083890 PMSD Stitch 8.037E-6 1.097E-3 9.827E-3 3.510E-2 2 5
33 ctd:C030370 2-methoxy-5-(2',3',4'-trimethoxyphenyl)tropone CTD 8.853E-6 1.172E-3 1.050E-2 3.866E-2 5 320
34 CID000023976 chromium Stitch 1.170E-5 1.498E-3 1.342E-2
5.110E-2
 5 339
35 ctd:C020711 beryllium sulfate CTD 1.201E-5 1.498E-3 1.342E-2
5.244E-2
 3 49
36 CID000479504 methylenedisalicylic acid Stitch 1.799E-5 2.183E-3 1.955E-2
7.857E-2
 3 56
37 CID000448050 1q91 Stitch 2.106E-5 2.486E-3 2.227E-2
9.199E-2
 3 59
38 ctd:D004917 Erythromycin CTD 2.692E-5 3.093E-3 2.771E-2
1.175E-1
 3 64
39 CID000124025 procyanidin A2 Stitch 2.887E-5 3.233E-3 2.896E-2
1.261E-1
 2 9
40 CID000008758 nitrilotriacetic acid Stitch 3.038E-5 3.317E-3 2.971E-2
1.327E-1
 4 200
41 CID000171612 baciphelacin Stitch 3.524E-5 3.753E-3 3.363E-2
1.539E-1
 3 70
42 CID000277822 D-Au Stitch 4.690E-5 4.876E-3 4.368E-2
2.048E-1
 3 77
43 CID000000899 N-acetylhexosamine Stitch 5.710E-5 5.799E-3
5.195E-2
2.493E-1
 5 472
44 CID000070743 m157 Stitch 6.241E-5 6.057E-3
5.427E-2
2.726E-1
 2 13
45 CID000189691 C2-O Stitch 6.241E-5 6.057E-3
5.427E-2
2.726E-1
 2 13
46 ctd:D007069 Ifosfamide CTD 7.020E-5 6.665E-3
5.971E-2
3.066E-1
 4 248
47 CID000015178 AGN-1133 Stitch 8.241E-5 7.657E-3
6.860E-2
3.599E-1
 3 93
48 CID000412305 AC1L937T Stitch 9.586E-5 8.721E-3
7.814E-2
4.186E-1
 2 16
49 ctd:C106538 abacavir CTD 1.086E-4 9.677E-3
8.670E-2
4.742E-1
 2 17
50 CID000447029 I-Hg Stitch 1.364E-4 1.182E-2
1.059E-1
5.956E-1
 2 19
Show 45 more annotations

18: Disease [Display Chart] 21 input genes in category / 1393 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0007570 Celiac Disease DisGeNET Curated 1.718E-13 1.347E-10 1.053E-9 2.393E-10 10 247
2 C2103602 Autoimmune Primary Adrenal Insufficiency DisGeNET BeFree 1.933E-13 1.347E-10 1.053E-9 2.693E-10 7 50
3 C1853959 Birdshot chorioretinopathy DisGeNET Curated 3.120E-11 1.449E-8 1.133E-7 4.347E-8 4 6
4 C0949691 Spondylarthropathies DisGeNET BeFree 4.239E-11 1.476E-8 1.154E-7 5.904E-8 6 52
5 C3714757 Juvenile rheumatoid arthritis DisGeNET Curated 1.631E-10 4.004E-8 3.129E-7 2.272E-7 7 127
6 C0566602 Primary sclerosing cholangitis DisGeNET Curated 1.724E-10 4.004E-8 3.129E-7 2.402E-7 7 128
7 C0271737 Addison's disease due to autoimmunity DisGeNET BeFree 2.109E-10 4.196E-8 3.280E-7 2.937E-7 5 28
8 C0949690 Spondylarthritis DisGeNET Curated 2.691E-10 4.686E-8 3.663E-7 3.749E-7 6 70
9 C0524910 Hepatitis C, Chronic DisGeNET Curated 3.287E-10 5.087E-8 3.977E-7 4.579E-7 9 367
10 C0543698 hypersensitive syndrome DisGeNET BeFree 4.354E-10 6.065E-8 4.741E-7 6.065E-7 4 10
11 C0178468 Autoimmune thyroid disease DisGeNET BeFree 1.985E-9 2.514E-7 1.965E-6 2.765E-6 6 97
12 C0018213 Graves Disease DisGeNET Curated 3.124E-9 3.537E-7 2.765E-6 4.351E-6 8 316
13 C0376545 Hematologic Neoplasms DisGeNET Curated 3.364E-9 3.537E-7 2.765E-6 4.686E-6 9 478
14 20090121:Silverberg Ulcerative colitis GWAS 3.754E-9 3.537E-7 2.765E-6 5.230E-6 4 16
15 C0003872 Arthritis, Psoriatic DisGeNET Curated 3.809E-9 3.537E-7 2.765E-6 5.306E-6 7 199
16 C0040100 Thymoma DisGeNET Curated 4.526E-9 3.941E-7 3.080E-6 6.305E-6 7 204
17 C1849193 PEELING SKIN SYNDROME DisGeNET Curated 4.905E-9 4.020E-7 3.142E-6 6.833E-6 4 17
18 C0263361 Psoriasis vulgaris DisGeNET BeFree 5.871E-9 4.540E-7 3.549E-6 8.178E-6 6 116
19 C0035854 Rosacea DisGeNET Curated 6.302E-9 4.540E-7 3.549E-6 8.778E-6 4 18
20 C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 6.809E-9 4.540E-7 3.549E-6 9.485E-6 8 349
21 C0524909 Hepatitis B, Chronic DisGeNET Curated 7.175E-9 4.540E-7 3.549E-6 9.995E-6 7 218
22 C0848034 Low IQ DisGeNET BeFree 7.496E-9 4.540E-7 3.549E-6 1.044E-5 3 4
23 C0751340 Myasthenia Gravis, Ocular DisGeNET BeFree 7.496E-9 4.540E-7 3.549E-6 1.044E-5 3 4
24 C0038013 Ankylosing spondylitis DisGeNET Curated 8.396E-9 4.873E-7 3.809E-6 1.170E-5 7 223
25 C1832588 Chromosome 11p11.2 Deletion Syndrome DisGeNET Curated 9.961E-9 5.550E-7 4.338E-6 1.388E-5 4 20
26 C3469186 HEMOCHROMATOSIS, TYPE 1 DisGeNET Curated 1.465E-8 7.850E-7 6.136E-6 2.041E-5 5 63
27 C0751356 Idiopathic Inflammatory Myopathies DisGeNET BeFree 1.719E-8 8.868E-7 6.932E-6 2.394E-5 5 65
28 C0002874 Aplastic Anemia DisGeNET Curated 1.821E-8 8.926E-7 6.977E-6 2.537E-5 6 140
29 C0001403 Addison Disease DisGeNET Curated 1.858E-8 8.926E-7 6.977E-6 2.589E-5 5 66
30 C0039263 Takayasu Arteritis DisGeNET Curated 2.590E-8 1.203E-6 9.400E-6 3.608E-5 4 25
31 C0036391 Schwartz-Jampel Syndrome DisGeNET Curated 3.058E-8 1.374E-6 1.074E-5 4.260E-5 4 26
32 C0040592 Trachoma DisGeNET BeFree 3.587E-8 1.561E-6 1.221E-5 4.997E-5 4 27
33 C0085786 Hamman-Rich syndrome DisGeNET BeFree 4.048E-8 1.709E-6 1.336E-5 5.640E-5 6 160
34 C0018995 Hemochromatosis DisGeNET Curated 4.346E-8 1.781E-6 1.392E-5 6.054E-5 5 78
35 C1333064 Classical Hodgkin's Lymphoma DisGeNET BeFree 4.523E-8 1.800E-6 1.407E-5 6.301E-5 6 163
36 C1960272 Latent autoimmune diabetes mellitus in adult DisGeNET BeFree 5.587E-8 2.112E-6 1.651E-5 7.783E-5 4 30
37 C0026896 Myasthenia Gravis DisGeNET Curated 5.610E-8 2.112E-6 1.651E-5 7.815E-5 6 169
38 C0856825 Acute GVH disease DisGeNET BeFree 5.811E-8 2.130E-6 1.665E-5 8.095E-5 6 170
39 C0086445 Idiopathic Membranous Glomerulonephritis DisGeNET BeFree 6.409E-8 2.278E-6 1.781E-5 8.928E-5 4 31
40 C0850024 Gluten sensitivity DisGeNET BeFree 6.543E-8 2.278E-6 1.781E-5 9.114E-5 3 7
41 C1384600 Systemic onset juvenile chronic arthritis DisGeNET Curated 7.319E-8 2.487E-6 1.944E-5 1.020E-4 4 32
42 C0011644 Scleroderma DisGeNET Curated 8.164E-8 2.696E-6 2.107E-5 1.137E-4 6 180
43 C0014518 Toxic Epidermal Necrolysis DisGeNET BeFree 8.321E-8 2.696E-6 2.107E-5 1.159E-4 4 33
44 C1290884 Inflammatory disorder DisGeNET BeFree 1.024E-7 3.242E-6 2.534E-5 1.426E-4 6 187
45 C0035439 Rheumatic Heart Disease DisGeNET BeFree 1.339E-7 4.144E-6 3.239E-5 1.865E-4 4 37
46 C0029134 Optic Neuritis DisGeNET Curated 1.495E-7 4.527E-6 3.538E-5 2.082E-4 4 38
47 C1304140 Familial psoriasis DisGeNET BeFree 1.568E-7 4.549E-6 3.556E-5 2.184E-4 3 9
48 C0342342 Idiopathic Hypoparathyroidism DisGeNET BeFree 1.568E-7 4.549E-6 3.556E-5 2.184E-4 3 9
49 C0036202 Sarcoidosis DisGeNET Curated 1.764E-7 5.016E-6 3.921E-5 2.458E-4 6 205
50 C0004943 Behcet Syndrome DisGeNET Curated 2.034E-7 5.569E-6 4.353E-5 2.834E-4 6 210
Show 45 more annotations