Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc222_13, positive side

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1: GO: Molecular Function [Display Chart] 13 input genes in category / 75 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0004896 cytokine receptor activity 2.686E-16 2.015E-14 9.875E-14 2.015E-14 8 90
2 GO:0019955 cytokine binding 2.119E-13 7.946E-12 3.894E-11 1.589E-11 7 103
3 GO:0004908 interleukin-1 receptor activity 9.893E-12 2.473E-10 1.212E-9 7.420E-10 4 8
4 GO:0001637 G protein-coupled chemoattractant receptor activity 1.776E-9 2.664E-8 1.306E-7 1.332E-7 4 25
5 GO:0004950 chemokine receptor activity 1.776E-9 2.664E-8 1.306E-7 1.332E-7 4 25
6 GO:0019966 interleukin-1 binding 2.213E-8 2.766E-7 1.356E-6 1.660E-6 3 9
7 GO:0019956 chemokine binding 3.487E-7 3.736E-6 1.831E-5 2.615E-5 3 21
8 GO:0004918 interleukin-8 receptor activity 4.480E-7 4.200E-6 2.059E-5 3.360E-5 2 2
9 GO:0019959 interleukin-8 binding 1.343E-6 1.120E-5 5.487E-5 1.008E-4 2 3
10 GO:0008528 G protein-coupled peptide receptor activity 1.628E-6 1.214E-5 5.951E-5 1.221E-4 4 132
11 GO:0001653 peptide receptor activity 1.781E-6 1.214E-5 5.951E-5 1.335E-4 4 135
12 GO:0016494 C-X-C chemokine receptor activity 9.390E-6 5.417E-5 2.655E-4 7.042E-4 2 7
13 GO:0019958 C-X-C chemokine binding 9.390E-6 5.417E-5 2.655E-4 7.042E-4 2 7
14 GO:0016493 C-C chemokine receptor activity 3.479E-5 1.864E-4 9.136E-4 2.609E-3 2 13
15 GO:0005149 interleukin-1 receptor binding 8.452E-5 4.226E-4 2.071E-3 6.339E-3 2 20
16 GO:0019838 growth factor binding 1.167E-4 5.256E-4 2.576E-3 8.750E-3 3 142
17 GO:0070851 growth factor receptor binding 1.191E-4 5.256E-4 2.576E-3 8.934E-3 3 143
18 GO:0042008 interleukin-18 receptor activity 6.966E-4 2.612E-3 1.280E-2
5.225E-2
 1 1
19 GO:0045353 interleukin-1 type II receptor antagonist activity 6.966E-4 2.612E-3 1.280E-2
5.225E-2
 1 1
20 GO:0045352 interleukin-1 type I receptor antagonist activity 6.966E-4 2.612E-3 1.280E-2
5.225E-2
 1 1
21 GO:0005151 interleukin-1, type II receptor binding 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
22 GO:0005150 interleukin-1, type I receptor binding 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
23 GO:0004909 interleukin-1, type I, activating receptor activity 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
24 GO:0005011 macrophage colony-stimulating factor receptor activity 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
25 GO:0004910 interleukin-1, type II, blocking receptor activity 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
26 GO:0035717 chemokine (C-C motif) ligand 7 binding 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
27 GO:0002114 interleukin-33 receptor activity 1.393E-3 3.869E-3 1.896E-2
1.045E-1
 1 2
28 GO:0071791 chemokine (C-C motif) ligand 5 binding 2.089E-3 5.401E-3 2.647E-2
1.566E-1
 1 3
29 GO:0005152 interleukin-1 receptor antagonist activity 2.089E-3 5.401E-3 2.647E-2
1.566E-1
 1 3
30 GO:0019957 C-C chemokine binding 4.867E-3 1.217E-2
5.964E-2
3.650E-1
 1 7
31 GO:0034235 GPI anchor binding 5.561E-3 1.345E-2
6.594E-2
4.170E-1
 1 8
32 GO:0048019 receptor antagonist activity 6.946E-3 1.628E-2
7.980E-2
5.210E-1
 1 10
33 GO:0030547 receptor inhibitor activity 9.712E-3 2.207E-2
1.082E-1
7.284E-1
 1 14
34 GO:0005161 platelet-derived growth factor receptor binding 1.178E-2 2.599E-2
1.274E-1
8.837E-1
 1 17
35 GO:0005537 mannose binding 1.316E-2 2.820E-2
1.382E-1
9.870E-1
 1 19
36 GO:0005126 cytokine receptor binding 1.666E-2 3.470E-2
1.701E-1
1.000E0
 2 289
37 GO:0051861 glycolipid binding 1.728E-2 3.503E-2
1.717E-1
1.000E0
 1 25
38 GO:0035255 ionotropic glutamate receptor binding 1.797E-2 3.546E-2
1.738E-1
1.000E0
 1 26
39 GO:0004435 phosphatidylinositol phospholipase C activity 1.934E-2 3.719E-2
1.823E-1
1.000E0
 1 28
40 GO:0001221 transcription cofactor binding 2.071E-2 3.882E-2
1.903E-1
1.000E0
 1 30
41 GO:0004629 phospholipase C activity 2.548E-2 4.661E-2
2.284E-1
1.000E0
 1 37
Show 36 more annotations

2: GO: Biological Process [Display Chart] 13 input genes in category / 666 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:2000659 regulation of interleukin-1-mediated signaling pathway 2.655E-9 1.768E-6 1.252E-5 1.768E-6 3 5
2 GO:0050900 leukocyte migration 1.158E-7 3.745E-5 2.651E-4 7.709E-5 6 386
3 GO:0070098 chemokine-mediated signaling pathway 2.192E-7 3.745E-5 2.651E-4 1.460E-4 4 80
4 GO:0070498 interleukin-1-mediated signaling pathway 2.558E-7 3.745E-5 2.651E-4 1.704E-4 3 19
5 GO:0002407 dendritic cell chemotaxis 4.061E-7 3.745E-5 2.651E-4 2.705E-4 3 22
6 GO:0098758 response to interleukin-8 4.498E-7 3.745E-5 2.651E-4 2.996E-4 2 2
7 GO:0098759 cellular response to interleukin-8 4.498E-7 3.745E-5 2.651E-4 2.996E-4 2 2
8 GO:0038112 interleukin-8-mediated signaling pathway 4.498E-7 3.745E-5 2.651E-4 2.996E-4 2 2
9 GO:0036336 dendritic cell migration 7.698E-7 5.696E-5 4.033E-4 5.127E-4 3 27
10 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway 1.349E-6 8.984E-5 6.360E-4 8.984E-4 2 3
11 GO:0097529 myeloid leukocyte migration 4.929E-6 2.984E-4 2.113E-3 3.283E-3 4 174
12 GO:0030595 leukocyte chemotaxis 8.556E-6 4.748E-4 3.361E-3 5.698E-3 4 200
13 GO:0060326 cell chemotaxis 2.228E-5 1.141E-3 8.079E-3 1.484E-2 4 255
14 GO:0007204 positive regulation of cytosolic calcium ion concentration 3.214E-5 1.529E-3 1.082E-2 2.140E-2 4 280
15 GO:0071347 cellular response to interleukin-1 3.772E-5 1.675E-3 1.186E-2 2.512E-2 3 97
16 GO:0051480 regulation of cytosolic calcium ion concentration 4.546E-5 1.892E-3 1.340E-2 3.028E-2 4 306
17 GO:0097530 granulocyte migration 7.662E-5 2.904E-3 2.056E-2
5.103E-2
 3 123
18 GO:0070555 response to interleukin-1 7.848E-5 2.904E-3 2.056E-2
5.227E-2
 3 124
19 GO:0002687 positive regulation of leukocyte migration 8.827E-5 3.094E-3 2.190E-2
5.879E-2
 3 129
20 GO:0001959 regulation of cytokine-mediated signaling pathway 1.198E-4 3.991E-3 2.825E-2
7.981E-2
 3 143
21 GO:0060759 regulation of response to cytokine stimulus 1.354E-4 4.293E-3 3.039E-2
9.015E-2
 3 149
22 GO:0006874 cellular calcium ion homeostasis 1.427E-4 4.321E-3 3.059E-2
9.505E-2
 4 411
23 GO:0055074 calcium ion homeostasis 1.624E-4 4.607E-3 3.261E-2
1.081E-1
 4 425
24 GO:0045672 positive regulation of osteoclast differentiation 1.683E-4 4.607E-3 3.261E-2
1.121E-1
 2 28
25 GO:0072503 cellular divalent inorganic cation homeostasis 1.776E-4 4.607E-3 3.261E-2
1.183E-1
 4 435
26 GO:0050708 regulation of protein secretion 1.921E-4 4.607E-3 3.261E-2
1.279E-1
 4 444
27 GO:0030335 positive regulation of cell migration 1.938E-4 4.607E-3 3.261E-2
1.290E-1
 4 445
28 GO:0050707 regulation of cytokine secretion 2.033E-4 4.607E-3 3.261E-2
1.354E-1
 3 171
29 GO:0072507 divalent inorganic cation homeostasis 2.164E-4 4.607E-3 3.261E-2
1.441E-1
 4 458
30 GO:2000147 positive regulation of cell motility 2.164E-4 4.607E-3 3.261E-2
1.441E-1
 4 458
31 GO:1902624 positive regulation of neutrophil migration 2.205E-4 4.607E-3 3.261E-2
1.468E-1
 2 32
32 GO:0002685 regulation of leukocyte migration 2.213E-4 4.607E-3 3.261E-2
1.474E-1
 3 176
33 GO:0051272 positive regulation of cellular component movement 2.389E-4 4.822E-3 3.414E-2
1.591E-1
 4 470
34 GO:0040017 positive regulation of locomotion 2.528E-4 4.953E-3 3.506E-2
1.684E-1
 4 477
35 GO:0050663 cytokine secretion 2.948E-4 5.609E-3 3.971E-2
1.963E-1
 3 194
36 GO:1902622 regulation of neutrophil migration 3.285E-4 6.077E-3 4.302E-2
2.188E-1
 2 39
37 GO:0001960 negative regulation of cytokine-mediated signaling pathway 3.997E-4 7.194E-3
5.093E-2
2.662E-1
 2 43
38 GO:0060761 negative regulation of response to cytokine stimulus 4.777E-4 8.373E-3
5.927E-2
3.182E-1
 2 47
39 GO:2000661 positive regulation of interleukin-1-mediated signaling pathway 6.981E-4 1.114E-2
7.887E-2
4.649E-1
 1 1
40 GO:0035623 renal glucose absorption 6.981E-4 1.114E-2
7.887E-2
4.649E-1
 1 1
41 GO:0035476 angioblast cell migration 6.981E-4 1.114E-2
7.887E-2
4.649E-1
 1 1
42 GO:0002763 positive regulation of myeloid leukocyte differentiation 7.025E-4 1.114E-2
7.887E-2
4.679E-1
 2 57
43 GO:0070371 ERK1 and ERK2 cascade 8.961E-4 1.382E-2
9.780E-2
5.968E-1
 3 284
44 GO:0006968 cellular defense response 9.127E-4 1.382E-2
9.780E-2
6.079E-1
 2 65
45 GO:0045453 bone resorption 9.694E-4 1.435E-2
1.016E-1
6.456E-1
 2 67
46 GO:0045670 regulation of osteoclast differentiation 1.150E-3 1.664E-2
1.178E-1
7.656E-1
 2 73
47 GO:0035655 interleukin-18-mediated signaling pathway 1.396E-3 1.817E-2
1.286E-1
9.295E-1
 1 2
48 GO:0032690 negative regulation of interleukin-1 alpha production 1.396E-3 1.817E-2
1.286E-1
9.295E-1
 1 2
49 GO:0050712 negative regulation of interleukin-1 alpha secretion 1.396E-3 1.817E-2
1.286E-1
9.295E-1
 1 2
50 GO:0038172 interleukin-33-mediated signaling pathway 1.396E-3 1.817E-2
1.286E-1
9.295E-1
 1 2
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 13 input genes in category / 33 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:1990682 CSF1-CSF1R complex 1.364E-3 4.500E-2
1.840E-1
 4.500E-2 1 2

4: Human Phenotype [Display Chart] 5 input genes in category / 609 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0010280 Stomatitis 7.737E-5 4.712E-2
3.293E-1
 4.712E-2 3 95

5: Mouse Phenotype [Display Chart] 13 input genes in category / 740 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0010210 abnormal circulating cytokine level 1.526E-6 1.129E-3 8.112E-3 1.129E-3 6 334
2 MP:0008713 abnormal cytokine level 7.470E-6 2.180E-3 1.567E-2 5.528E-3 6 439
3 MP:0008835 abnormal intercellular signaling peptide or protein level 8.840E-6 2.180E-3 1.567E-2 6.541E-3 6 452
4 MP:0011518 abnormal cell chemotaxis 1.967E-5 3.612E-3 2.595E-2 1.456E-2 4 138
5 MP:0002334 abnormal airway responsiveness 2.755E-5 3.612E-3 2.595E-2 2.039E-2 3 49
6 MP:0002330 abnormal bronchial provocation 2.929E-5 3.612E-3 2.595E-2 2.167E-2 3 50
7 MP:0010214 abnormal circulating serum amyloid protein level 4.057E-5 4.289E-3 3.081E-2 3.002E-2 2 8
8 MP:0008719 impaired neutrophil recruitment 5.076E-5 4.695E-3 3.373E-2 3.756E-2 3 60
9 MP:0003436 decreased susceptibility to induced arthritis 7.721E-5 5.714E-3 4.105E-2
5.714E-2
 3 69
10 MP:0003079 decreased susceptibility to induced joint inflammation 7.721E-5 5.714E-3 4.105E-2
5.714E-2
 3 69
11 MP:0005351 decreased susceptibility to autoimmune disorder 8.755E-5 5.890E-3 4.231E-2
6.479E-2
 4 202
12 MP:0008721 abnormal chemokine level 1.114E-4 6.868E-3 4.935E-2
8.242E-2
 3 78
13 MP:0000223 decreased monocyte cell number 1.649E-4 9.167E-3
6.586E-2
1.221E-1
 3 89
14 MP:0002414 abnormal myeloblast morphology/development 1.734E-4 9.167E-3
6.586E-2
1.283E-1
 4 241
15 MP:0012441 abnormal monocyte cell number 1.967E-4 9.524E-3
6.843E-2
1.455E-1
 4 249
16 MP:0008588 abnormal circulating interleukin level 2.059E-4 9.524E-3
6.843E-2
1.524E-1
 4 252
17 MP:0002620 abnormal monocyte morphology 2.188E-4 9.524E-3
6.843E-2
1.619E-1
 4 256
18 MP:0002462 abnormal granulocyte physiology 2.392E-4 9.832E-3
7.064E-2
1.770E-1
 4 262
19 MP:0002411 decreased susceptibility to bacterial infection 2.768E-4 1.078E-2
7.744E-2
2.048E-1
 3 106
20 MP:0001862 interstitial pneumonia 3.314E-4 1.226E-2
8.809E-2
2.452E-1
 2 22
21 MP:0008751 abnormal interleukin level 3.814E-4 1.330E-2
9.555E-2
2.822E-1
 4 296
22 MP:0010211 abnormal acute phase protein level 3.954E-4 1.330E-2
9.555E-2
2.926E-1
 2 24
23 MP:0008125 abnormal dendritic cell number 4.602E-4 1.433E-2
1.030E-1
3.406E-1
 3 126
24 MP:0002335 decreased airway responsiveness 4.649E-4 1.433E-2
1.030E-1
3.440E-1
 2 26
25 MP:0002425 altered susceptibility to autoimmune disorder 6.102E-4 1.753E-2
1.259E-1
4.515E-1
 4 335
26 MP:0020186 altered susceptibility to bacterial infection 6.241E-4 1.753E-2
1.259E-1
4.618E-1
 4 337
27 MP:0002993 arthritis 6.396E-4 1.753E-2
1.259E-1
4.733E-1
 3 141
28 MP:0002465 abnormal eosinophil physiology 7.065E-4 1.807E-2
1.298E-1
5.228E-1
 2 32
29 MP:0008595 abnormal circulating interleukin-6 level 7.080E-4 1.807E-2
1.298E-1
5.239E-1
 3 146
30 MP:0002933 joint inflammation 7.961E-4 1.964E-2
1.411E-1
5.891E-1
 3 152
31 MP:0000119 abnormal tooth eruption 8.457E-4 1.999E-2
1.436E-1
6.258E-1
 2 35
32 MP:0020183 altered susceptibility to fungal infection 8.948E-4 1.999E-2
1.436E-1
6.622E-1
 2 36
33 MP:0005461 abnormal dendritic cell morphology 9.074E-4 1.999E-2
1.436E-1
6.715E-1
 3 159
34 MP:0002500 granulomatous inflammation 9.453E-4 1.999E-2
1.436E-1
6.995E-1
 2 37
35 MP:0003724 increased susceptibility to induced arthritis 9.453E-4 1.999E-2
1.436E-1
6.995E-1
 2 37
36 MP:0002602 abnormal eosinophil cell number 9.752E-4 2.005E-2
1.440E-1
7.217E-1
 3 163
37 MP:0005061 abnormal eosinophil morphology 1.028E-3 2.056E-2
1.477E-1
7.608E-1
 3 166
38 MP:0013520 increased CD4-positive NK T cell number 1.255E-3 2.281E-2
1.639E-1
9.290E-1
 1 1
39 MP:0013523 increased memory-marker CD4-positive NK T cell number 1.255E-3 2.281E-2
1.639E-1
9.290E-1
 1 1
40 MP:0002463 abnormal neutrophil physiology 1.279E-3 2.281E-2
1.639E-1
9.462E-1
 3 179
41 MP:0020185 altered susceptibility to viral infection 1.320E-3 2.281E-2
1.639E-1
9.770E-1
 3 181
42 MP:0009789 decreased susceptibility to bacterial infection induced morbidity/mortality 1.336E-3 2.281E-2
1.639E-1
9.887E-1
 2 44
43 MP:0001844 autoimmune response 1.412E-3 2.281E-2
1.639E-1
1.000E0
 4 419
44 MP:0008704 abnormal interleukin-6 secretion 1.428E-3 2.281E-2
1.639E-1
1.000E0
 3 186
45 MP:0005005 abnormal self tolerance 1.437E-3 2.281E-2
1.639E-1
1.000E0
 4 421
46 MP:0004956 decreased thymus weight 1.460E-3 2.281E-2
1.639E-1
1.000E0
 2 46
47 MP:0008657 increased interleukin-1 beta secretion 1.460E-3 2.281E-2
1.639E-1
1.000E0
 2 46
48 MP:0002327 abnormal respiratory function 1.502E-3 2.281E-2
1.639E-1
1.000E0
 4 426
49 MP:0009785 altered susceptibility to infection induced morbidity/mortality 1.518E-3 2.281E-2
1.639E-1
1.000E0
 3 190
50 MP:0005000 abnormal immune tolerance 1.541E-3 2.281E-2
1.639E-1
1.000E0
 4 429
Show 45 more annotations

6: Domain [Display Chart] 13 input genes in category / 69 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR004074 IL-1 rcpt I/II-typ InterPro 2.088E-12 1.441E-10 6.943E-10 1.441E-10 4 6
2 IPR015621 IL-1 rcpt fam InterPro 4.585E-11 1.582E-9 7.623E-9 3.164E-9 4 11
3 IPR003599 Ig sub InterPro 4.205E-9 7.254E-8 3.495E-7 2.901E-7 7 421
4 SM00409 IG SMART 4.205E-9 7.254E-8 3.495E-7 2.901E-7 7 421
5 PS50835 IG LIKE PROSITE 1.236E-8 1.705E-7 8.216E-7 8.526E-7 7 492
6 IPR013151 Immunoglobulin InterPro 1.226E-7 1.209E-6 5.824E-6 8.461E-6 5 190
7 PF00047 ig Pfam 1.226E-7 1.209E-6 5.824E-6 8.461E-6 5 190
8 SM00255 TIR SMART 3.446E-7 2.876E-6 1.386E-5 2.378E-5 3 21
9 PF01582 TIR Pfam 3.989E-7 2.876E-6 1.386E-5 2.752E-5 3 22
10 IPR000174 Chemokine CXCR 1/2 InterPro 4.445E-7 2.876E-6 1.386E-5 3.067E-5 2 2
11 3.40.50.10140 - Gene3D 4.585E-7 2.876E-6 1.386E-5 3.164E-5 3 23
12 PS50104 TIR PROSITE 5.238E-7 3.012E-6 1.451E-5 3.614E-5 3 24
13 IPR000157 TIR dom InterPro 5.950E-7 3.158E-6 1.522E-5 4.106E-5 3 25
14 IPR001277 CXCR4/ACKR2 InterPro 9.316E-6 4.591E-5 2.212E-4 6.428E-4 2 7
15 IPR000355 Chemokine rcpt InterPro 5.304E-5 2.440E-4 1.176E-3 3.660E-3 2 16
16 IPR013106 Ig V-set InterPro 3.167E-4 1.366E-3 6.582E-3 2.186E-2 3 200
17 IPR003598 Ig sub2 InterPro 5.078E-4 1.773E-3 8.545E-3 3.504E-2 3 235
18 SM00408 IGc2 SMART 5.078E-4 1.773E-3 8.545E-3 3.504E-2 3 235
19 IPR027166 IL-1RA InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
20 IPR001355 Chemokine CXCR1 InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
21 IPR033292 THY1 InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
22 IPR002238 Chemokine CCR3 InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
23 IPR002236 Chemokine CCR1 InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
24 IPR030658 CSF-1 receptor InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
25 IPR006898 HNF1a C InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
26 PF04813 HNF-1A C Pfam 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
27 IPR000057 Chemokine CXCR2 InterPro 6.939E-4 1.773E-3 8.545E-3 4.788E-2 1 1
28 IPR004076 IL-1 rcpt I-typ InterPro 1.387E-3 2.901E-3 1.398E-2
9.573E-2
 1 2
29 IPR009151 Basigin InterPro 1.387E-3 2.901E-3 1.398E-2
9.573E-2
 1 2
30 PF04812 HNF-1B C Pfam 1.387E-3 2.901E-3 1.398E-2
9.573E-2
 1 2
31 IPR006897 HNF1b C InterPro 1.387E-3 2.901E-3 1.398E-2
9.573E-2
 1 2
32 IPR004077 IL-1 rcpt II-typ InterPro 1.387E-3 2.901E-3 1.398E-2
9.573E-2
 1 2
33 IPR023219 HNF1 dimer dom InterPro 1.387E-3 2.901E-3 1.398E-2
9.573E-2
 1 2
34 IPR006899 HNF-1 N InterPro 2.080E-3 4.101E-3 1.976E-2
1.435E-1
 1 3
35 PF04814 HNF-1 N Pfam 2.080E-3 4.101E-3 1.976E-2
1.435E-1
 1 3
36 IPR020877 IL-1 CS InterPro 2.773E-3 5.315E-3 2.561E-2
1.913E-1
 1 4
37 IPR003297 IL-1RA/IL-36 InterPro 3.465E-3 6.462E-3 3.114E-2
2.391E-1
 1 5
38 IPR016243 Tyr kinase CSF1/PDGF rcpt InterPro 4.157E-3 7.548E-3 3.637E-2
2.868E-1
 1 6
39 PS00240 RECEPTOR TYR KIN III PROSITE 5.539E-3 9.554E-3 4.604E-2
3.822E-1
 1 8
40 IPR001824 Tyr kinase rcpt 3 CS InterPro 5.539E-3 9.554E-3 4.604E-2
3.822E-1
 1 8
41 PS00253 INTERLEUKIN 1 PROSITE 6.229E-3 1.023E-2 4.931E-2
4.298E-1
 1 9
42 PF00340 IL1 Pfam 6.229E-3 1.023E-2 4.931E-2
4.298E-1
 1 9
43 IPR000975 IL-1 fam InterPro 6.919E-3 1.104E-2
5.321E-2
4.774E-1
 1 10
44 PF07686 V-set Pfam 7.042E-3 1.104E-2
5.321E-2
4.859E-1
 2 185
45 PF07679 I-set Pfam 7.415E-3 1.112E-2
5.359E-2
5.116E-1
 2 190
46 IPR013098 Ig I-set InterPro 7.415E-3 1.112E-2
5.359E-2
5.116E-1
 2 190
47 1.10.260.40 - Gene3D 1.858E-2 2.728E-2
1.314E-1
1.000E0
 1 27
48 IPR010982 Lambda DNA-bd dom InterPro 1.994E-2 2.867E-2
1.381E-1
1.000E0
 1 29
49 IPR008996 Cytokine IL1-like InterPro 2.470E-2 3.478E-2
1.676E-1
1.000E0
 1 36
Show 44 more annotations

7: Pathway [Display Chart] 13 input genes in category / 83 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 83051 Cytokine-cytokine receptor interaction BioSystems: KEGG 6.161E-13 5.114E-11 2.558E-10 5.114E-11 9 270
2 1269320 Interleukin-1 signaling BioSystems: REACTOME 1.138E-7 3.061E-6 1.531E-5 9.446E-6 4 46
3 1269547 Chemokine receptors bind chemokines BioSystems: REACTOME 1.355E-7 3.061E-6 1.531E-5 1.125E-5 4 48
4 1470924 Interleukin-10 signaling BioSystems: REACTOME 1.475E-7 3.061E-6 1.531E-5 1.224E-5 4 49
5 M4047 Selective expression of chemokine receptors during T-cell polarization MSigDB C2 BIOCARTA (v6.0) 3.199E-6 5.311E-5 2.657E-4 2.656E-4 3 29
6 M12095 Signal transduction through IL1R MSigDB C2 BIOCARTA (v6.0) 4.766E-6 6.593E-5 3.298E-4 3.956E-4 3 33
7 137944 IL1-mediated signaling events BioSystems: Pathway Interaction Database 5.710E-6 6.771E-5 3.387E-4 4.739E-4 3 35
8 99051 Chemokine signaling pathway BioSystems: KEGG 2.850E-5 2.859E-4 1.430E-3 2.365E-3 4 182
9 1269546 Peptide ligand-binding receptors BioSystems: REACTOME 3.237E-5 2.859E-4 1.430E-3 2.686E-3 4 188
10 P00031 Inflammation mediated by chemokine and cytokine signaling pathway PantherDB 3.444E-5 2.859E-4 1.430E-3 2.859E-3 4 191
11 1269576 G alpha (i) signalling events BioSystems: REACTOME 8.813E-5 6.650E-4 3.326E-3 7.315E-3 4 243
12 83078 Hematopoietic cell lineage BioSystems: KEGG 1.239E-4 8.570E-4 4.287E-3 1.028E-2 3 97
13 1269545 Class A/1 (Rhodopsin-like receptors) BioSystems: REACTOME 2.610E-4 1.667E-3 8.336E-3 2.167E-2 4 322
14 1269544 GPCR ligand binding BioSystems: REACTOME 9.676E-4 5.737E-3 2.870E-2
8.031E-2
 4 455
15 137922 IL12-mediated signaling events BioSystems: Pathway Interaction Database 1.779E-3 9.844E-3 4.924E-2
1.477E-1
 2 61
16 102279 Endocytosis BioSystems: KEGG 2.205E-3 1.077E-2
5.386E-2
1.830E-1
 3 260
17 83102 Epithelial cell signaling in Helicobacter pylori infection BioSystems: KEGG 2.205E-3 1.077E-2
5.386E-2
1.830E-1
 2 68
18 P00036 Interleukin signaling pathway PantherDB 3.996E-3 1.839E-2
9.199E-2
3.316E-1
 2 92
19 167324 Amoebiasis BioSystems: KEGG 4.343E-3 1.839E-2
9.199E-2
3.604E-1
 2 96
20 948277 Inflammatory mediator regulation of TRP channels BioSystems: KEGG 4.431E-3 1.839E-2
9.199E-2
3.678E-1
 2 97
21 1469482 Th17 cell differentiation BioSystems: KEGG 5.366E-3 2.121E-2
1.061E-1
4.454E-1
 2 107
22 1269929 Proton-coupled monocarboxylate transport BioSystems: REACTOME 7.288E-3 2.750E-2
1.375E-1
6.049E-1
 1 7
23 193147 Osteoclast differentiation BioSystems: KEGG 7.827E-3 2.825E-2
1.413E-1
6.496E-1
 2 130
24 1474302 Fluid shear stress and atherosclerosis BioSystems: KEGG 9.279E-3 3.209E-2
1.605E-1
7.702E-1
 2 142
25 1311074 Phospholipase D signaling pathway BioSystems: KEGG 9.788E-3 3.250E-2
1.625E-1
8.124E-1
 2 146
26 M18928 IL 5 Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 1.040E-2 3.319E-2
1.660E-1
8.629E-1
 1 10
27 M16973 CBL mediated ligand-induced downregulation of EGF receptors MSigDB C2 BIOCARTA (v6.0) 1.350E-2 3.910E-2
1.956E-1
1.000E0
 1 13
28 M13247 T Cytotoxic Cell Surface Molecules MSigDB C2 BIOCARTA (v6.0) 1.453E-2 3.910E-2
1.956E-1
1.000E0
 1 14
29 M6427 T Helper Cell Surface Molecules MSigDB C2 BIOCARTA (v6.0) 1.453E-2 3.910E-2
1.956E-1
1.000E0
 1 14
30 M16173 Presenilin action in Notch and Wnt signaling MSigDB C2 BIOCARTA (v6.0) 1.453E-2 3.910E-2
1.956E-1
1.000E0
 1 14
31 523016 Transcriptional misregulation in cancer BioSystems: KEGG 1.460E-2 3.910E-2
1.956E-1
1.000E0
 2 180
32 138046 Syndecan-1-mediated signaling events BioSystems: Pathway Interaction Database 1.761E-2 4.569E-2
2.285E-1
1.000E0
 1 17
33 M14449 METS affect on Macrophage Differentiation MSigDB C2 BIOCARTA (v6.0) 1.864E-2 4.664E-2
2.333E-1
1.000E0
 1 18
34 M6705 Th1/Th2 Differentiation MSigDB C2 BIOCARTA (v6.0) 1.967E-2 4.664E-2
2.333E-1
1.000E0
 1 19
35 M10547 Role of MAL in Rho-Mediated Activation of SRF MSigDB C2 BIOCARTA (v6.0) 1.967E-2 4.664E-2
2.333E-1
1.000E0
 1 19
Show 30 more annotations

8: Pubmed [Display Chart] 13 input genes in category / 5130 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20353565 Allelic variants of IL1R1 gene associate with severe hand osteoarthritis. Pubmed 1.015E-12 5.209E-9 4.750E-8 5.209E-9 4 9
2 18805969 Interleukin-1-mediated hematopoietic cell regulation in the aorta-gonad-mesonephros region of the mouse embryo. Pubmed 1.915E-11 2.411E-8 2.198E-7 9.824E-8 4 17
3 24489825 HIV-1 Nef down-modulates C-C and C-X-C chemokine receptors via ubiquitin and ubiquitin-independent mechanism. Pubmed 1.915E-11 2.411E-8 2.198E-7 9.824E-8 4 17
4 11846196 Smoking and polymorphisms of the interleukin-1 gene cluster (IL-1alpha, IL-1beta, and IL-1RN) in patients with periodontal disease. Pubmed 3.080E-11 2.411E-8 2.198E-7 1.580E-7 3 3
5 8706893 Co-expression of mRNA for type I and type II interleukin-1 receptors and the IL-1 receptor accessory protein correlates to IL-1 responsiveness. Pubmed 3.080E-11 2.411E-8 2.198E-7 1.580E-7 3 3
6 20503287 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Pubmed 3.588E-11 2.411E-8 2.198E-7 1.840E-7 6 204
7 19258923 Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Pubmed 3.695E-11 2.411E-8 2.198E-7 1.896E-7 6 205
8 17703412 Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. Pubmed 3.918E-11 2.411E-8 2.198E-7 2.010E-7 6 207
9 20140262 Maternal and fetal genetic associations of PTGER3 and PON1 with preterm birth. Pubmed 4.229E-11 2.411E-8 2.198E-7 2.170E-7 5 79
10 17413037 Haplotypes of IL1B, IL1RN, IL1R1, and IL1R2 and the risk of venous thrombosis. Pubmed 1.232E-10 6.320E-8 5.764E-7 6.320E-7 3 4
11 10191101 Interleukin-1 receptor cluster: gene organization of IL1R2, IL1R1, IL1RL2 (IL-1Rrp2), IL1RL1 (T1/ST2), and IL18R1 (IL-1Rrp) on human chromosome 2q. Pubmed 3.079E-10 1.436E-7 1.310E-6 1.580E-6 3 5
12 19019335 Spontaneous preterm birth in African Americans is associated with infection and inflammatory response gene variants. Pubmed 4.366E-10 1.804E-7 1.645E-6 2.240E-6 5 125
13 19527514 Racial disparity in pathophysiologic pathways of preterm birth based on genetic variants. Pubmed 4.922E-10 1.804E-7 1.645E-6 2.525E-6 5 128
14 18818748 Preterm birth in Caucasians is associated with coagulation and inflammation pathway gene variants. Pubmed 4.922E-10 1.804E-7 1.645E-6 2.525E-6 5 128
15 17672867 Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease. Pubmed 6.157E-10 1.974E-7 1.800E-6 3.159E-6 3 6
16 19079579 MyD88 is required for protection from lethal infection with a mouse-adapted SARS-CoV. Pubmed 6.157E-10 1.974E-7 1.800E-6 3.159E-6 3 6
17 19573080 Common genetic variants in candidate genes and risk of familial lymphoid malignancies. Pubmed 9.241E-10 2.789E-7 2.543E-6 4.741E-6 5 145
18 10734056 Regulation of the human chemokine receptor CCR1. Cross-regulation by CXCR1 and CXCR2. Pubmed 1.077E-9 2.909E-7 2.653E-6 5.526E-6 3 7
19 24651866 IL-1α and complement cooperate in triggering local neutrophilic inflammation in response to adenovirus and eliminating virus-containing cells. Pubmed 1.077E-9 2.909E-7 2.653E-6 5.526E-6 3 7
20 16621978 The multiple personalities of the chemokine receptor CCR7 in dendritic cells. Pubmed 1.723E-9 4.420E-7 4.031E-6 8.841E-6 3 8
21 20452482 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Pubmed 3.325E-9 8.122E-7 7.407E-6 1.706E-5 5 187
22 10479460 Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Pubmed 3.691E-9 8.608E-7 7.850E-6 1.894E-5 3 10
23 19773279 Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity. Pubmed 1.834E-8 4.090E-6 3.730E-5 9.407E-5 5 263
24 20568250 Common single nucleotide polymorphisms in immunoregulatory genes and multiple myeloma risk among women in Connecticut. Pubmed 2.524E-8 4.610E-6 4.205E-5 1.295E-4 4 95
25 18311140 Newly identified genetic risk variants for celiac disease related to the immune response. Pubmed 2.975E-8 4.610E-6 4.205E-5 1.526E-4 3 19
26 23128233 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Pubmed 6.785E-8 4.610E-6 4.205E-5 3.480E-4 5 342
27 19180518 Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowing. Pubmed 7.054E-8 4.610E-6 4.205E-5 3.619E-4 3 25
28 20802378 A multiplex MALDI-TOF MS approach facilitates genotyping of DNA from formalin-fixed paraffin-embedded tumour specimens. Pubmed 7.054E-8 4.610E-6 4.205E-5 3.619E-4 3 25
29 23708969 Neutrophil swarms require LTB4 and integrins at sites of cell death in vivo. Pubmed 1.004E-7 4.610E-6 4.205E-5 5.151E-4 3 28
30 12794150 Variations in eosinophil chemokine responses: an investigation of CCR1 and CCR3 function, expression in atopy, and identification of a functional CCR1 promoter. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
31 17823985 Anti-type II collagen antibody accelerates arthritis via CXCR2-expressing cells in IL-1 receptor antagonist-deficient mice. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
32 9166705 Type I and type II interleukin-1 receptor expression in rat, mouse, and human testes. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
33 24818754 Interleukin-1 receptor gene variants are associated with aggressive periodontitis in the Japanese. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
34 19401689 CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
35 8127400 Corticosteroid regulation of IL-1 receptors in the mouse hippocampus: effects of glucocorticoid treatment, stress, and adrenalectomy. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
36 26847910 Repertaxin, an inhibitor of the chemokine receptors CXCR1 and CXCR2, inhibits malignant behavior of human gastric cancer MKN45 cells in vitro and in vivo and enhances efficacy of 5-fluorouracil. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
37 15939811 Elastic-vessel arteritis in interleukin-1 receptor antagonist-deficient mice involves effector Th1 cells and requires interleukin-1 receptor. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
38 25986216 A polymorphism in CCR1/CCR3 is associated with narcolepsy. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
39 20082763 [Effects of Xiaotan Sanjie Decoction on expressions of interleukin-8 and its receptors in gastric tumor xenografts and gastric tissue adjacent to the tumor in mice]. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
40 12239185 Phagocytosing neutrophils down-regulate the expression of chemokine receptors CXCR1 and CXCR2. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
41 15653174 Genotypes and haplotypes in the IL-1 gene cluster: analysis of two genetically and diagnostically distinct groups of Alzheimer patients. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
42 7877456 Expression of type I and type II interleukin-1 receptors in mouse brain. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
43 26087179 CXCR1/2 antagonism with CXCL8/Interleukin-8 analogue CXCL8(3-72)K11R/G31P restricts lung cancer growth by inhibiting tumor cell proliferation and suppressing angiogenesis. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
44 1387148 Pattern of IL-1 receptor gene expression suggests role in noninflammatory processes. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
45 14734209 Polymorphism of interleukin-1 receptor antagonist gene and obesity. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
46 14713106 Expression of CXCR1 and CXCR2 receptors in malignant melanoma with different metastatic potential and their role in interleukin-8 (CXCL-8)-mediated modulation of metastatic phenotype. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
47 25839897 Role of interleukin-1 receptor signaling in the behavioral effects of ethanol and benzodiazepines. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
48 21036625 CXCR1 and CXCR2 are novel mechano-sensors mediating laminar shear stress-induced endothelial cell migration. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
49 25022956 Association of CXCR1 and 2 expressions with gastric cancer metastasis in ex vivo and tumor cell invasion in vitro. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
50 10094132 Chemokine receptor mRNA expression at the in vitro blood-brain barrier during HIV infection. Pubmed 1.069E-7 4.610E-6 4.205E-5 5.486E-4 2 2
Show 45 more annotations

9: Interaction [Display Chart] 13 input genes in category / 414 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:IL1RAP IL1RAP interactions 2.192E-9 9.075E-7 5.994E-6 9.075E-7 4 25
2 int:IL1RN IL1RN interactions 5.087E-8 7.017E-6 4.634E-5 2.106E-5 3 11
3 int:GNA14 GNA14 interactions 6.780E-8 7.017E-6 4.634E-5 2.807E-5 3 12
4 int:IL1A IL1A interactions 6.780E-8 7.017E-6 4.634E-5 2.807E-5 3 12
5 int:IL1R1 IL1R1 interactions 7.049E-7 5.837E-5 3.855E-4 2.918E-4 3 25
6 int:IL1B IL1B interactions 8.957E-7 6.180E-5 4.082E-4 3.708E-4 3 27
7 int:CCL15 CCL15 interactions 1.493E-6 8.829E-5 5.831E-4 6.180E-4 2 3
8 int:CCL26 CCL26 interactions 2.984E-6 1.373E-4 9.066E-4 1.236E-3 2 4
9 int:CXCL6 CXCL6 interactions 2.984E-6 1.373E-4 9.066E-4 1.236E-3 2 4
10 int:IL1R2 IL1R2 interactions 3.753E-6 1.554E-4 1.026E-3 1.554E-3 3 43
11 int:IL18R1 IL18R1 interactions 4.972E-6 1.583E-4 1.046E-3 2.058E-3 2 5
12 int:CCL3L3 CCL3L3 interactions 4.972E-6 1.583E-4 1.046E-3 2.058E-3 2 5
13 int:CCL3L1 CCL3L1 interactions 4.972E-6 1.583E-4 1.046E-3 2.058E-3 2 5
14 int:CXCL5 CXCL5 interactions 7.455E-6 2.204E-4 1.456E-3 3.086E-3 2 6
15 int:CXCL3 CXCL3 interactions 1.043E-5 2.879E-4 1.902E-3 4.319E-3 2 7
16 int:CXCL2 CXCL2 interactions 1.390E-5 3.598E-4 2.376E-3 5.756E-3 2 8
17 int:MARCH8 MARCH8 interactions 1.787E-5 4.352E-4 2.874E-3 7.398E-3 2 9
18 int:CCL8 CCL8 interactions 2.233E-5 5.135E-4 3.391E-3 9.243E-3 2 10
19 int:CXCL1 CXCL1 interactions 2.728E-5 5.646E-4 3.729E-3 1.129E-2 2 11
20 int:ADRA1A ADRA1A interactions 2.728E-5 5.646E-4 3.729E-3 1.129E-2 2 11
21 int:CCL4 CCL4 interactions 3.272E-5 6.450E-4 4.260E-3 1.355E-2 2 12
22 int:CCL14 CCL14 interactions 4.508E-5 8.114E-4 5.358E-3 1.866E-2 2 14
23 int:CCL3 CCL3 interactions 4.508E-5 8.114E-4 5.358E-3 1.866E-2 2 14
24 int:STAT3 STAT3 interactions 5.257E-5 9.068E-4 5.989E-3 2.176E-2 4 302
25 int:CXCR1 CXCR1 interactions 6.728E-5 1.114E-3 7.358E-3 2.785E-2 2 17
26 int:CCL7 CCL7 interactions 7.566E-5 1.205E-3 7.956E-3 3.132E-2 2 18
27 int:TICAM2 TICAM2 interactions 1.037E-4 1.590E-3 1.050E-2 4.294E-2 2 21
28 int:PPBP PPBP interactions 1.140E-4 1.628E-3 1.075E-2 4.721E-2 2 22
29 int:CCL2 CCL2 interactions 1.140E-4 1.628E-3 1.075E-2 4.721E-2 2 22
30 int:CXCR2 CXCR2 interactions 1.249E-4 1.723E-3 1.138E-2
5.169E-2
 2 23
31 int:GNA15 GNA15 interactions 1.361E-4 1.818E-3 1.201E-2
5.636E-2
 2 24
32 int:CXCL8 CXCL8 interactions 1.729E-4 2.237E-3 1.478E-2
7.159E-2
 2 27
33 int:NLRX1 NLRX1 interactions 2.439E-4 3.059E-3 2.020E-2
1.010E-1
 2 32
34 int:DSTYK DSTYK interactions 3.448E-4 4.078E-3 2.693E-2
1.427E-1
 2 38
35 int:GNPAT GNPAT interactions 3.448E-4 4.078E-3 2.693E-2
1.427E-1
 2 38
36 int:CTDSP2 CTDSP2 interactions 3.822E-4 4.396E-3 2.903E-2
1.582E-1
 2 40
37 int:CCL5 CCL5 interactions 4.216E-4 4.717E-3 3.115E-2
1.745E-1
 2 42
38 int:EXOC2 EXOC2 interactions 5.509E-4 5.848E-3 3.862E-2
2.281E-1
 2 48
39 int:DNM3 DNM3 interactions 5.509E-4 5.848E-3 3.862E-2
2.281E-1
 2 48
40 int:PIK3R1 PIK3R1 interactions 7.251E-4 7.504E-3 4.956E-2
3.002E-1
 3 251
41 int:EXOC3 EXOC3 interactions 7.766E-4 7.842E-3
5.179E-2
3.215E-1
 2 57
42 int:TBCD TBCD interactions 8.890E-4 8.763E-3
5.787E-2
3.680E-1
 2 61
43 int:EXOC4 EXOC4 interactions 1.071E-3 1.032E-2
6.813E-2
4.436E-1
 2 67
44 int:ITGAV ITGAV interactions 1.412E-3 1.329E-2
8.774E-2
5.846E-1
 2 77
45 int:CCL24 CCL24 interactions 1.468E-3 1.351E-2
8.921E-2
6.078E-1
 1 2
46 int:MYD88 MYD88 interactions 1.523E-3 1.371E-2
9.053E-2
6.305E-1
 2 80
47 int:TOLLIP TOLLIP interactions 1.965E-3 1.731E-2
1.143E-1
8.134E-1
 2 91
48 int:SLC16A4 SLC16A4 interactions 2.202E-3 1.860E-2
1.228E-1
9.114E-1
 1 3
49 int:IL1F10 IL1F10 interactions 2.202E-3 1.860E-2
1.228E-1
9.114E-1
 1 3
50 int:EXOC1 EXOC1 interactions 2.556E-3 2.116E-2
1.398E-1
1.000E0
 2 104
Show 45 more annotations

10: Cytoband [Display Chart] 13 input genes in category / 10 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 2q12 2q12 9.049E-9 9.049E-8 2.650E-7 9.049E-8 3 12
2 2q35 2q35 4.138E-4 2.069E-3 6.059E-3 4.138E-3 2 81
3 12q24.2 12q24.2 5.985E-3 1.869E-2
5.475E-2
5.985E-2
 1 16
4 2q14.2 2q14.2 7.477E-3 1.869E-2
5.475E-2
7.477E-2
 1 20
5 3q28 3q28 1.157E-2 2.113E-2
6.190E-2
1.157E-1
 1 31
6 3p21 3p21 1.268E-2 2.113E-2
6.190E-2
1.268E-1
 1 34
7 5q32 5q32 2.044E-2 2.784E-2
8.155E-2
2.044E-1
 1 55
8 3p21.3 3p21.3 2.228E-2 2.784E-2
8.155E-2
2.228E-1
 1 60
9 11q23.3 11q23.3 3.069E-2 3.410E-2
9.988E-2
3.069E-1
 1 83
Show 4 more annotations

11: Transcription Factor Binding Site [Display Chart] 11 input genes in category / 71 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 13 input genes in category / 12 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 602 Fibronectin type III domain containing|Interleukin receptors genenames.org 3.504E-16 4.205E-15 1.305E-14 4.205E-15 7 42
2 471 CD molecules|Tumor necrosis factor superfamily genenames.org 5.468E-15 3.281E-14 1.018E-13 6.562E-14 10 394
3 594 Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing genenames.org 2.204E-11 8.816E-11 2.736E-10 2.645E-10 7 193
4 1296 TIR domain containing genenames.org 1.290E-7 3.871E-7 1.201E-6 1.548E-6 3 15
5 1094 CD molecules|C-X-C motif chemokine receptors genenames.org 7.058E-6 1.694E-5 5.257E-5 8.470E-5 2 6
6 1091 C-C motif chemokine receptors genenames.org 2.114E-5 4.228E-5 1.312E-4 2.537E-4 2 10
7 524 HNF class homeoboxes genenames.org 2.142E-3 3.672E-3 1.140E-2 2.571E-2 1 3
8 593 Fibronectin type III domain containing|I-set domain containing|Immunoglobulin like domain containing genenames.org 5.694E-3 8.540E-3 2.650E-2
6.832E-2
 2 161
9 454 Blood group antigens genenames.org 2.613E-2 3.306E-2
1.026E-1
3.135E-1
 1 37
10 321 Receptor Tyrosine Kinases|Protein phosphatase 1 regulatory subunits genenames.org 2.822E-2 3.306E-2
1.026E-1
3.386E-1
 1 40
11 601 Interleukins|PDZ domain containing genenames.org 3.030E-2 3.306E-2
1.026E-1
3.636E-1
 1 43
Show 6 more annotations

13: Coexpression [Display Chart] 13 input genes in category / 1815 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20460173-ImmPortCytokineReceptors Human Immune Kong10 308genes ImmPort CytokineReceptors GeneSigDB 6.873E-15 1.247E-11 1.008E-10 1.247E-11 9 303
2 20460173-ImmPortInterleukinReceptors Human Immune Kong10 43genes ImmPort InterleukinReceptors GeneSigDB 3.066E-14 2.783E-11 2.249E-10 5.565E-11 6 40
3 17174972-TableS1 Human Zola07 426genes CellDifferentiationMarkers GeneSigDB 2.719E-12 1.645E-9 1.329E-8 4.935E-9 8 345
4 12130493-Table6 Mouse StemCell Ma02 42genes GeneSigDB 1.728E-11 7.842E-9 6.337E-8 3.137E-8 5 41
5 12946996-Table3 Human Lymphoma Kaminski03 33genes GeneSigDB 4.357E-10 1.582E-7 1.278E-6 7.908E-7 4 22
6 20220088-SuppTable2b Human Immune Allen10 42genes GeneSigDB 2.429E-9 7.348E-7 5.938E-6 4.409E-6 4 33
7 14522937-Table1 Human Kidney Twine03 132genes GeneSigDB 4.118E-9 1.068E-6 8.629E-6 7.475E-6 5 119
8 20460173-ImmPortChemokineReceptors Human Immune Kong10 53genes ImmPort ChemokineReceptors GeneSigDB 1.597E-8 3.624E-6 2.929E-5 2.899E-5 4 52
9 M11428 Inflammatory cytokines, chemokines and their cognate receptors up-regulated in THP-1 cells (monocyte) after treatment with PSMD4 [GeneID=5710]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.381E-8 1.204E-5 9.726E-5 1.158E-4 4 73
10 19795415-Table1 Mouse Lung Beisiegel09 262genes GeneSigDB 6.631E-8 1.204E-5 9.726E-5 1.204E-4 5 207
11 M5897 Genes up-regulated by IL6 [GeneID=3569] via STAT3 [GeneID=6774], e.g., during acute phase response. MSigDB H: Hallmark Gene Sets (v6.0) 1.299E-7 2.144E-5 1.732E-4 2.358E-4 4 87
12 17671223-Table1 Human HeadandNeck Yoon07 22genes GeneSigDB 1.571E-7 2.376E-5 1.920E-4 2.851E-4 3 20
13 M1986 Inflammatory cytokines and their receptors moduated in brain tumors in response to treatment with cyclic RGD peptide prior to the oncocytic virus therapy. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.832E-7 2.558E-5 2.067E-4 3.325E-4 3 21
14 16270046-SuppTable1 Human Lymphoma Martinez-Delgado05 135genes GeneSigDB 2.774E-7 3.597E-5 2.907E-4 5.036E-4 4 105
15 20220088-SuppTable2 Human Immune Allen10 162genes GeneSigDB 3.597E-7 4.352E-5 3.517E-4 6.528E-4 4 112
16 19797726-Table2b Human Lymphoma VanLoo09 40genes GeneSigDB 1.252E-6 1.333E-4 1.077E-3 2.272E-3 3 39
17 19014521-TableS6b Human Breast Reyal08 159genes GeneSigDB 1.288E-6 1.333E-4 1.077E-3 2.338E-3 4 154
18 16081686-SuppTable2 Human Lymphoma Tome05 357genes GeneSigDB 1.322E-6 1.333E-4 1.077E-3 2.399E-3 4 155
19 16423051-Table1 Human Leukemia Larsson06 44genes GeneSigDB 1.688E-6 1.612E-4 1.303E-3 3.064E-3 3 43
20 M1985 Inflammatory cytokines and their receptors modulated in brain tumors after treatment with an oncocytic virus, a potential anticancer therapy. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.811E-6 1.643E-4 1.328E-3 3.287E-3 3 44
21 12917485-Table6 Human Breast Sotiriou03 606genes ER GeneSigDB 3.251E-6 2.450E-4 1.980E-3 5.901E-3 5 455
22 M3310 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) before vs after YF17D vaccination. MSigDB C7: Immunologic Signatures (v6.0) 3.364E-6 2.450E-4 1.980E-3 6.105E-3 4 196
23 16423051-Table3 Human Leukemia Larsson06 54genes GeneSigDB 3.381E-6 2.450E-4 1.980E-3 6.136E-3 3 54
24 M5776 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from patients with type 1 diabetes at the time of diagnosis. MSigDB C7: Immunologic Signatures (v6.0) 3.573E-6 2.450E-4 1.980E-3 6.485E-3 4 199
25 M5235 Genes up-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 3.573E-6 2.450E-4 1.980E-3 6.485E-3 4 199
26 M4559 Genes up-regulated in comparison of adult thymic progenitors versus adult DN2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.645E-6 2.450E-4 1.980E-3 6.615E-3 4 200
27 M3082 Genes down-regulated in comparison of healthy B cells versus healthy myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 3.645E-6 2.450E-4 1.980E-3 6.615E-3 4 200
28 M16088 Genes up-regulated at 3 months of age in lungs from LIPA [GeneID=3988] knockout mice, which display pulmonary pathology. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.424E-6 2.867E-4 2.317E-3 8.029E-3 3 59
29 M4345 Genes up-regulated at 6 months of age in lungs from LIPA [GeneID=3988] knockout mice, which display pulmonary pathology. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.778E-6 5.494E-4 4.440E-3 1.593E-2 3 74
30 M1560 Cluster 6: late responding genes activated in ATM [GeneID=472] deficient but not in the wild type tissues. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.286E-5 7.781E-4 6.288E-3 2.334E-2 3 84
31 M5149 Neutrophil-specific genes down-regulated in comparison of immature with mature neutrophils. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.265E-5 1.307E-3 1.056E-2 4.111E-2 2 13
32 17018861-TableS1 Human StemCell Ehrchen07 102genes GeneSigDB 2.304E-5 1.307E-3 1.056E-2 4.182E-2 3 102
33 12446012-Table2 Mouse Immune Carmody02 151genes GeneSigDB 3.048E-5 1.677E-3 1.355E-2
5.533E-2
 3 112
34 17895889-Table1b Human Leukemia Hamamura07 17genes GeneSigDB 3.482E-5 1.859E-3 1.502E-2
6.319E-2
 2 16
35 18435859-ShorterGeneList Mouse Breast Piechocki08 558genes GeneSigDB 4.370E-5 2.266E-3 1.831E-2
7.932E-2
 4 376
36 M2568 Genes up-regulated in lung tissue upon LPS aspiration with mechanical ventilation (MV) compared to control (PBS aspiration without MV). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.542E-5 2.290E-3 1.851E-2
8.244E-2
 3 128
37 17206280-TableS1C Mouse Breast Park07 173genes GeneSigDB 4.757E-5 2.334E-3 1.886E-2
8.634E-2
 3 130
38 M8637 Genes down-regulated in MCF10A cells (breast cancer) by expression of LSM1 [GeneID=27257] off a letiviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.957E-5 2.367E-3 1.913E-2
8.996E-2
 2 19
39 M1007 Nearest neighbors of TAL1 [GeneID=6886], based on the close agreement of their expression profiles with that of TAL1 in pediatric T cell acute lymphoblastic leukemia (T-ALL) MSigDB C2: CGP Curated Gene Sets (v6.0) 6.083E-5 2.831E-3 2.288E-2
1.104E-1
 2 21
40 M3645 Genes up-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.265E-5 3.750E-3 3.031E-2
1.500E-1
 4 443
41 M1430 Genes defining differentiation potential of the bipotential myeloid cell line FDB. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.665E-5 4.187E-3 3.384E-2
1.754E-1
 3 165
42 M2925 Genes down-regulated in skin: wildtype (BALB/c) versus IFNAR1 [GeneID=3454] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.170E-4 4.187E-3 3.384E-2
2.124E-1
 3 176
43 M3282 Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) versus PBMC 3 days after stimulation with YF17D vaccine. MSigDB C7: Immunologic Signatures (v6.0) 1.560E-4 4.187E-3 3.384E-2
2.832E-1
 3 194
44 M6163 Genes down-regulated in D10.G4.1 T cell line (0.8h): control versus treated with NMU [GeneID=10874]. MSigDB C7: Immunologic Signatures (v6.0) 1.633E-4 4.187E-3 3.384E-2
2.963E-1
 3 197
45 M3351 Genes up-regulated in comparison of polysome bound (translated) mRNA in dendritic cells (DC) at 4 h after LPS (TLR4 agonist) stimulation versus those at 16 h after the stimulation. MSigDB C7: Immunologic Signatures (v6.0) 1.657E-4 4.187E-3 3.384E-2
3.008E-1
 3 198
46 M4466 Genes up-regulated in comparison of neuthrophils versus monocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.682E-4 4.187E-3 3.384E-2
3.053E-1
 3 199
47 M3653 Genes down-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after treatment with trichostatin A (TSA) [PubChem=5562]. MSigDB C7: Immunologic Signatures (v6.0) 1.682E-4 4.187E-3 3.384E-2
3.053E-1
 3 199
48 M5273 Genes up-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]. MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 4.187E-3 3.384E-2
3.098E-1
 3 200
49 M5730 Genes up-regulated in comparison of thymus regulatory T cells versus thymus conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 4.187E-3 3.384E-2
3.098E-1
 3 200
50 M5185 Genes up-regulated in comparison of dendritic cells (DC) exposed to 50 worm/well B. malayi versus macrophages exposed to 50 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 4.187E-3 3.384E-2
3.098E-1
 3 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 13 input genes in category / 1585 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM854309 100 Myeloid Cells, GN.Thio.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 4.917E-10 5.530E-7 4.394E-6 7.793E-7 5 74
2 GSM854306 500 Myeloid Cells, GN.Bl, CD11b+ Ly6-G+, Blood, avg-3 Immgen.org, GSE15907 1.200E-9 5.530E-7 4.394E-6 1.901E-6 7 409
3 GSM854312 500 Myeloid Cells, GN.UrAc.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 1.220E-9 5.530E-7 4.394E-6 1.934E-6 7 410
4 GSM854338 500 Myeloid Cells, GN.Arth.SynF, CD11b+ Ly6-G+, Synovial Fluid, avg-3 Immgen.org, GSE15907 1.395E-9 5.530E-7 4.394E-6 2.212E-6 7 418
5 GSM538351 500 B cells, proB.FrA.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R+ CD117+ IL7R+, Bone marrow, avg-1 Immgen.org, GSE15907 5.210E-8 1.423E-5 1.131E-4 8.258E-5 6 395
6 GSM605846 500 Myeloid Cells, GN.BM, CD11b+ Ly6-G+, Bone marrow, avg-4 Immgen.org, GSE15907 6.981E-8 1.423E-5 1.131E-4 1.107E-4 6 415
7 GSM854309 500 Myeloid Cells, GN.Thio.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 7.082E-8 1.423E-5 1.131E-4 1.122E-4 6 416
8 GSM854312 100 Myeloid Cells, GN.UrAc.PC, CD11b+ Ly6-G+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 7.184E-8 1.423E-5 1.131E-4 1.139E-4 4 71
9 GSM854338 100 Myeloid Cells, GN.Arth.SynF, CD11b+ Ly6-G+, Synovial Fluid, avg-3 Immgen.org, GSE15907 9.471E-8 1.668E-5 1.325E-4 1.501E-4 4 76
10 GSM854269 500 Myeloid Cells, DC.103-11b+24+.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24+, Lung, avg-2 Immgen.org, GSE15907 2.412E-6 3.188E-4 2.533E-3 3.824E-3 5 404
11 GSM538343 500 B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24- AA4.1+ CD45R- CD117+ IL7R+, Bone marrow, avg-1 Immgen.org, GSE15907 2.442E-6 3.188E-4 2.533E-3 3.870E-3 5 405
12 GSM605823 500 Myeloid Cells, DC.103-11b+.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3 Immgen.org, GSE15907 2.562E-6 3.188E-4 2.533E-3 4.061E-3 5 409
13 GSM538239 500 Myeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3 Immgen.org, GSE15907 2.624E-6 3.188E-4 2.533E-3 4.159E-3 5 411
14 GSM854303 500 Myeloid Cells, GN.Arth.BM, CD11b+ Ly6-G+, Bone marrow, avg-3 Immgen.org, GSE15907 2.918E-6 3.188E-4 2.533E-3 4.625E-3 5 420
15 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/granulocyte Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/granulocyte Tabula Muris Consortium 3.017E-6 3.188E-4 2.533E-3 4.782E-3 4 180
16 GSM854276 100 Myeloid Cells, DC.11cloSer.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-lo CD11b+, Small Intestine, avg-4 Immgen.org, GSE15907 3.799E-6 3.764E-4 2.991E-3 6.022E-3 3 53
17 Lungmap Mouse Lung PND3 Myeloid Subtype Myeloid-A Lungmap Mouse Lung PND3 Myeloid Subtype Myeloid-A Lungmap CCHMC 5.252E-6 4.897E-4 3.891E-3 8.325E-3 4 207
18 GSM854258 100 Myeloid Cells, DC.103-11b+.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD11b+ CD103- F480+, Small Intestine, avg-4 Immgen.org, GSE15907 6.418E-6 5.652E-4 4.491E-3 1.017E-2 3 63
19 GSM854262 100 Myeloid Cells, DC.103-11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103- F4/80+, Small Intestine, avg-7 Immgen.org, GSE15907 1.087E-5 9.067E-4 7.205E-3 1.723E-2 3 75
20 GSM476672 100 gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3 Immgen.org, GSE15907 1.370E-5 1.025E-3 8.141E-3 2.172E-2 3 81
21 GSM605823 100 Myeloid Cells, DC.103-11b+.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3 Immgen.org, GSE15907 1.370E-5 1.025E-3 8.141E-3 2.172E-2 3 81
22 GSM538335 100 alpha beta T cells, NKT.44+NK1.1-.Th, aGC CD1d tet CD3 CD44, Thymus, avg-3 Immgen.org, GSE15907 1.422E-5 1.025E-3 8.141E-3 2.254E-2 3 82
23 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D Top 200 Genes 1.611E-5 1.064E-3 8.455E-3 2.554E-2 4 275
24 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D PND07-28 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D PND07-28 Top 200 Genes 1.611E-5 1.064E-3 8.455E-3 2.554E-2 4 275
25 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/leukocyte Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/leukocyte Tabula Muris Consortium 1.819E-5 1.153E-3 9.164E-3 2.883E-2 3 89
26 Mouse Lung Development Lungmap Mouse Fluidigm Endothelial Subtype endothelial cells D PND01-03 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Endothelial Subtype endothelial cells D PND01-03 Top 200 Genes 2.419E-5 1.475E-3 1.172E-2 3.834E-2 4 305
27 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype myeloid - neutrophil, Lgals3-negative PND01-03 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype myeloid - neutrophil, Lgals3-negative PND01-03 Top 200 Genes 2.711E-5 1.591E-3 1.264E-2 4.297E-2 4 314
28 GSM777024 500 B cells, B.Pl.AA4+220+.BM, CD138+ AA4.1+ CD43- CD45R+, Bone marrow, avg-3 Immgen.org, GSE15907 3.574E-5 1.976E-3 1.570E-2
5.665E-2
 4 337
29 GSM538347 500 B cells, proB.CLP.BM, AA4.1+ CD117+ IL7R+ CD45R- CD24- CD19- IgM-, Bone marrow, avg-1 Immgen.org, GSE15907 3.615E-5 1.976E-3 1.570E-2
5.731E-2
 4 338
30 GSM854324 500 Myeloid Cells, MF.Sbcaps.SLN, CD11b+ CD169+ F4/80-, Lymph Node, avg-2 Immgen.org, GSE15907 3.917E-5 2.069E-3 1.644E-2
6.208E-2
 4 345
31 GSM854276 500 Myeloid Cells, DC.11cloSer.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-lo CD11b+, Small Intestine, avg-4 Immgen.org, GSE15907 4.827E-5 2.468E-3 1.961E-2
7.651E-2
 4 364
32 GSM854258 500 Myeloid Cells, DC.103-11b+.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD11b+ CD103- F480+, Small Intestine, avg-4 Immgen.org, GSE15907 5.037E-5 2.495E-3 1.982E-2
7.984E-2
 4 368
33 GSM854280 500 Myeloid Cells, DC.11cloSer.SI, CD45+ MHCII+ CD11c-lo CD11b+, Small Intestine, avg-5 Immgen.org, GSE15907 5.534E-5 2.611E-3 2.075E-2
8.771E-2
 4 377
34 GSM854232 500 Myeloid Cells, DC.103+11b+.Salm3.SI, CD45+ MHCII+ Gr1- CD11c-hi CD11b+ CD103+ F480-, Small Intestine, avg-5 Immgen.org, GSE15907 5.649E-5 2.611E-3 2.075E-2
8.954E-2
 4 379
35 GSM854262 500 Myeloid Cells, DC.103-11b+.SI, CD45+ MHCII+ CD11c-hi CD11b+ CD103- F4/80+, Small Intestine, avg-7 Immgen.org, GSE15907 5.766E-5 2.611E-3 2.075E-2
9.139E-2
 4 381
36 GSM854322 500 Myeloid Cells, MF.Medl.SLN, CD11b+ CD169+ F4/80+, Lymph Node, avg-2 Immgen.org, GSE15907 6.377E-5 2.786E-3 2.214E-2
1.011E-1
 4 391
37 GSM476672 500 gamma delta T cells, Tgd.Sp, TCRd+ CD3e+, Spleen, avg-3 Immgen.org, GSE15907 6.504E-5 2.786E-3 2.214E-2
1.031E-1
 4 393
38 GSM854302 500 Stromal Cells, Ep.MEChi.Th, CD45-EpCAm+Ly51-MHCIIhi, Thymus, avg-1 Immgen.org, GSE15907 7.739E-5 3.154E-3 2.506E-2
1.227E-1
 4 411
39 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Mucinous Colon Adenocarcinoma/4/1 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Mucinous Colon Adenocarcinoma/4/1 TCGA-Colorectal 7.819E-5 3.154E-3 2.506E-2
1.239E-1
 3 145
40 GSM854271 500 Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2 Immgen.org, GSE15907 7.960E-5 3.154E-3 2.506E-2
1.262E-1
 4 414
41 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Overall Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Overall Top 200 Genes 9.901E-5 3.828E-3 3.041E-2
1.569E-1
 3 157
42 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Overall Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Overall Top 200 Genes 1.106E-4 4.122E-3 3.275E-2
1.754E-1
 3 163
43 GSM538280 500 Myeloid Cells, DC.LC.Sk, MHCII+ CD11b+ CD45+, Skin, avg-2 Immgen.org, GSE15907 1.118E-4 4.122E-3 3.275E-2
1.772E-1
 4 452
44 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Testicular Germ Cell Tumor/4/1 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Testicular Germ Cell Tumor/4/1 TCGA-Testes 1.231E-4 4.436E-3 3.525E-2
1.952E-1
 3 169
45 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/basophil Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/basophil Tabula Muris Consortium 1.609E-4 5.667E-3 4.503E-2
2.550E-1
 3 185
46 appendix appendix Human Protein Atlas 1.768E-4 5.929E-3 4.711E-2
2.802E-1
 3 191
47 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND07-28 Top 200 Genes 1.768E-4 5.929E-3 4.711E-2
2.802E-1
 3 191
48 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B Top 200 Genes 1.795E-4 5.929E-3 4.711E-2
2.846E-1
 3 192
49 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-A Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-A Top 200 Genes 1.937E-4 6.231E-3 4.951E-2
3.070E-1
 3 197
50 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage - intermediate - unactivated Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage - intermediate - unactivated Top 200 Genes 1.995E-4 6.231E-3 4.951E-2
3.163E-1
 3 199
Show 45 more annotations

15: Computational [Display Chart] 12 input genes in category / 126 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M18643 MODULE 73 Genes in the cancer module 73. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.110E-11 3.918E-9 2.123E-8 3.918E-9 5 23
2 M6286 MODULE 265 Caner module 265: IL receptors. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.738E-8 1.725E-6 9.344E-6 3.450E-6 4 29
3 M10747 MODULE 545 IL-1 signaling. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.472E-6 5.843E-5 3.166E-4 1.854E-4 3 20
4 M17322 MODULE 76 Inflammatory response. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.855E-6 5.843E-5 3.166E-4 2.337E-4 4 81
5 M491 MODULE 288 Genes in the cancer module 288. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.917E-6 2.499E-4 1.354E-3 1.250E-3 3 37
6 M688 MODULE 27 Genes in the cancer module 27. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.471E-5 7.290E-4 3.949E-3 4.374E-3 5 355
7 M15983 MODULE 46 Genes in the cancer module 46. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.728E-5 9.468E-4 5.129E-3 7.217E-3 5 394
8 M12401 MODULE 75 Immune response. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.011E-5 9.468E-4 5.129E-3 7.574E-3 5 398
9 M11185 MODULE 128 Genes in the cancer module 128. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.863E-4 2.333E-3 1.264E-2 2.347E-2 3 98
10 M8286 MODULE 79 Genes in the cancer module 79. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.978E-4 2.333E-3 1.264E-2 2.492E-2 3 100
11 M2944 MODULE 170 Immune response. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.037E-4 2.333E-3 1.264E-2 2.567E-2 3 101
12 M18076 MODULE 367 Genes in the cancer module 367. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.226E-4 5.487E-3 2.973E-2
6.584E-2
 2 29
13 M7015 MODULE 263 Chemotaxis (chemokines). MSigDb: C4 - CM: Cancer Modules (v6.0) 1.261E-3 1.222E-2
6.620E-2
1.589E-1
 2 45
14 M6482 MODULE 108 Genes in the cancer module 108. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.947E-3 1.752E-2
9.493E-2
2.453E-1
 2 56
15 M19922 MODULE 291 B-cell malignancies expression clusters. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.614E-3 2.196E-2
1.190E-1
3.294E-1
 2 65
16 M7788 MODULE 241 Genes in the cancer module 241. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.285E-3 2.587E-2
1.402E-1
4.139E-1
 2 73
17 M4843 MODULE 174 Genes in the cancer module 174. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.500E-3 4.077E-2
2.209E-1
6.931E-1
 2 95
18 M6672 MODULE 146 Genes in the cancer module 146. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.316E-3 4.269E-2
2.313E-1
7.958E-1
 2 102
19 M17931 MORF PTPRR Neighborhood of PTPRR MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.437E-3 4.269E-2
2.313E-1
8.111E-1
 2 103
20 M14443 MODULE 147 GPCR. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.931E-3 4.366E-2
2.365E-1
8.733E-1
 2 107
Show 15 more annotations

16: MicroRNA [Display Chart] 13 input genes in category / 153 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-22-3p:Functional MTI Functional MTI miRTarbase 3.172E-6 4.853E-4 2.723E-3 4.853E-4 3 163
2 hsa-miR-181d-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.691E-6 7.414E-4 4.160E-3 1.483E-3 2 26
3 hsa-miR-95:mirSVR highEffct hsa-miR-95:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.399E-4 1.223E-2
6.864E-2
 3.670E-2 2 128
4 hsa-miR-1249:mirSVR lowEffct hsa-miR-1249:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 1.423E-3 3.984E-2
2.235E-1
2.177E-1
 2 314
5 hsa-miR-615-5p:mirSVR highEffct hsa-miR-615-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.523E-3 3.984E-2
2.235E-1
2.330E-1
 2 325
6 hsa-miR-4283:mirSVR highEffct hsa-miR-4283:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.782E-3 3.984E-2
2.235E-1
2.727E-1
 2 352
7 hsa-miR-1306-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.157E-3 3.984E-2
2.235E-1
3.301E-1
 1 12
8 hsa-miR-4292:mirSVR highEffct hsa-miR-4292:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.280E-3 3.984E-2
2.235E-1
3.488E-1
 2 399
9 hsa-miR-122*:mirSVR lowEffct hsa-miR-122*:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.451E-3 3.984E-2
2.235E-1
3.750E-1
 2 414
10 hsa-miR-132*:mirSVR lowEffct hsa-miR-132*:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.604E-3 3.984E-2
2.235E-1
3.984E-1
 2 427
11 hsa-miR-4449:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.235E-3 4.433E-2
2.487E-1
4.949E-1
 1 18
12 hsa-miR-3147:mirSVR highEffct hsa-miR-3147:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.476E-3 4.433E-2
2.487E-1
5.319E-1
 2 495
13 hsa-miR-6717-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.131E-3 4.862E-2
2.728E-1
6.321E-1
 1 23
Show 8 more annotations

17: Drug [Display Chart] 13 input genes in category / 5160 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ctd:D062610 Fungal Polysaccharides CTD 1.584E-12 8.175E-9 7.460E-8 8.175E-9 6 74
2 CID005486816 Dale Stitch 3.174E-10 8.189E-7 7.473E-6 1.638E-6 5 71
3 CID000065014 AMD3100 Stitch 4.808E-10 8.270E-7 7.547E-6 2.481E-6 5 77
4 CID010447660 IL-1R antagonist Stitch 1.479E-9 1.908E-6 1.741E-5 7.633E-6 5 96
5 CID000053040 Ai-a Stitch 2.114E-9 2.182E-6 1.991E-5 1.091E-5 5 103
6 ctd:C118980 antileukinate CTD 2.878E-9 2.475E-6 2.258E-5 1.485E-5 3 6
7 CID002735209 AC1MC2T1 Stitch 6.312E-9 4.653E-6 4.246E-5 3.257E-5 4 41
8 CID000369605 NF-058 Stitch 8.052E-9 5.194E-6 4.740E-5 4.155E-5 3 8
9 CID000183789 TAK-779 Stitch 1.016E-8 5.822E-6 5.314E-5 5.240E-5 4 46
10 ctd:C433788 lipopolysaccharide, E. coli O26-B6 CTD 1.188E-8 6.132E-6 5.596E-5 6.132E-5 5 145
11 ctd:C015380 neoechinulin CTD 1.317E-8 6.179E-6 5.639E-5 6.797E-5 4 49
12 ctd:C031238 zinc sulfide CTD 1.553E-8 6.677E-6 6.093E-5 8.012E-5 4 51
13 ctd:C000488 cladosporin CTD 1.818E-8 7.217E-6 6.586E-5 9.382E-5 4 53
14 CID000097711 g130 Stitch 3.021E-8 1.039E-5 9.485E-5 1.559E-4 4 60
15 CID000005106 AC1L1H8O Stitch 3.021E-8 1.039E-5 9.485E-5 1.559E-4 4 60
16 ctd:D009183 Mycotoxins CTD 5.033E-8 1.585E-5 1.447E-4 2.597E-4 4 68
17 CID000557593 glycyl-L-histidyl-L-lysine acetate Stitch 5.223E-8 1.585E-5 1.447E-4 2.695E-4 3 14
18 ctd:C402696 TMC 120A CTD 7.495E-8 2.149E-5 1.961E-4 3.867E-4 4 75
19 ctd:C007262 deoxynivalenol CTD 1.312E-7 3.562E-5 3.251E-4 6.768E-4 6 483
20 CID004634228 AC1NDZPB Stitch 1.603E-7 4.135E-5 3.773E-4 8.269E-4 5 244
21 CID000449422 bis-amidinium derivative of hoechst 33258 Stitch 1.790E-7 4.399E-5 4.014E-4 9.238E-4 4 93
22 CID003081257 Peptide 78 Stitch 2.920E-7 6.849E-5 6.250E-4 1.507E-3 4 105
23 ctd:C063609 1,2-dimethyl-4-nitrobenzene CTD 4.180E-7 9.377E-5 8.557E-4 2.157E-3 3 27
24 ctd:D009173 Mycophenolic Acid CTD 4.511E-7 9.700E-5 8.852E-4 2.328E-3 4 117
25 CID000445886 AC1L9IPU Stitch 5.218E-7 1.077E-4 9.828E-4 2.692E-3 3 29
26 ctd:D009578 Nitrobenzenes CTD 5.796E-7 1.150E-4 1.050E-3 2.991E-3 3 30
27 CID000004455 neopterine Stitch 7.542E-7 1.402E-4 1.280E-3 3.892E-3 4 133
28 CID000011549 dimethylcyclohexane Stitch 8.968E-7 1.402E-4 1.280E-3 4.627E-3 2 3
29 CID000166909 DTTA Stitch 8.968E-7 1.402E-4 1.280E-3 4.627E-3 2 3
30 ctd:D007476 Ionophores CTD 8.968E-7 1.402E-4 1.280E-3 4.627E-3 2 3
31 CID002781329 diaminocyclobut-3-ene-1,2-dione Stitch 8.968E-7 1.402E-4 1.280E-3 4.627E-3 2 3
32 CID000482146 HCC-1 variant Stitch 8.968E-7 1.402E-4 1.280E-3 4.627E-3 2 3
33 CID000095695 5-methoxysalicylaldehyde Stitch 8.968E-7 1.402E-4 1.280E-3 4.627E-3 2 3
34 CID000054454 simvastatin Stitch 1.626E-6 2.340E-4 2.135E-3 8.393E-3 5 390
35 CID000125053 S-TDCM Stitch 1.632E-6 2.340E-4 2.135E-3 8.423E-3 3 42
36 CID000065958 balofloxacin Stitch 1.632E-6 2.340E-4 2.135E-3 8.423E-3 3 42
37 ctd:C060209 deltorphin II, Ala(2)- CTD 1.793E-6 2.435E-4 2.222E-3 9.252E-3 2 4
38 CID000077197 nitroethylene Stitch 1.793E-6 2.435E-4 2.222E-3 9.252E-3 2 4
39 ctd:D015054 Zymosan CTD 2.106E-6 2.786E-4 2.542E-3 1.086E-2 4 172
40 ctd:C006794 brevianamide A CTD 2.454E-6 3.166E-4 2.890E-3 1.266E-2 3 48
41 CID000177837 1k1n Stitch 2.636E-6 3.318E-4 3.028E-3 1.360E-2 4 182
42 CID000445801 1ga8 Stitch 2.753E-6 3.383E-4 3.087E-3 1.421E-2 4 184
43 4076 UP Propylthiouracil [51-52-5]; Up 200; 23.4uM; PC3; HT HG-U133A Broad Institute CMAP Up 3.759E-6 4.510E-4 4.116E-3 1.939E-2 4 199
44 CID000005208 alkannin Stitch 4.364E-6 4.918E-4 4.488E-3 2.252E-2 3 58
45 ctd:C021065 oleandrin CTD 4.480E-6 4.918E-4 4.488E-3 2.312E-2 2 6
46 CID007019167 2-methoxy-6-methylaminopyridine Stitch 4.480E-6 4.918E-4 4.488E-3 2.312E-2 2 6
47 CID000192788 M 129 Stitch 4.480E-6 4.918E-4 4.488E-3 2.312E-2 2 6
48 CID004369063 AC1N9ZLR Stitch 4.830E-6 5.193E-4 4.739E-3 2.493E-2 4 212
49 CID010998045 CID10998045 Stitch 6.270E-6 6.343E-4 5.789E-3 3.235E-2 2 7
50 ctd:C490707 2-(4-isobutylphenyl)propionylmethanesulfonamide CTD 6.270E-6 6.343E-4 5.789E-3 3.235E-2 2 7
Show 45 more annotations

18: Disease [Display Chart] 13 input genes in category / 788 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0020517 Hypersensitivity DisGeNET Curated 1.444E-7 1.074E-4 7.781E-4 1.138E-4 4 63
2 20081125:Hunt Celiac disease GWAS 2.725E-7 1.074E-4 7.781E-4 2.147E-4 3 17
3 C0004943 Behcet Syndrome DisGeNET Curated 4.122E-7 1.083E-4 7.846E-4 3.248E-4 5 210
4 C0032285 Pneumonia DisGeNET Curated 8.964E-7 1.766E-4 1.280E-3 7.063E-4 6 476
5 C0349639 Juvenile Myelomonocytic Leukemia DisGeNET Curated 1.755E-6 2.766E-4 2.004E-3 1.383E-3 4 117
6 C0027697 Nephritis DisGeNET Curated 3.295E-6 3.875E-4 2.809E-3 2.596E-3 4 137
7 C0036220 Kaposi Sarcoma DisGeNET Curated 3.443E-6 3.875E-4 2.809E-3 2.713E-3 5 323
8 C3875321 Inflammatory dermatosis DisGeNET BeFree 4.602E-6 4.533E-4 3.285E-3 3.626E-3 4 149
9 C0153252 Systemic candidiasis DisGeNET BeFree 6.002E-6 4.811E-4 3.487E-3 4.729E-3 3 46
10 C0085786 Hamman-Rich syndrome DisGeNET BeFree 6.106E-6 4.811E-4 3.487E-3 4.811E-3 4 160
11 C0011603 Dermatitis DisGeNET Curated 8.321E-6 5.961E-4 4.320E-3 6.557E-3 4 173
12 C0155877 Allergic asthma DisGeNET BeFree 1.390E-5 8.997E-4 6.520E-3 1.095E-2 4 197
13 C3665444 Neutrophilia (disorder) DisGeNET BeFree 1.484E-5 8.997E-4 6.520E-3 1.170E-2 3 62
14 C0206180 Ki-1+ Anaplastic Large Cell Lymphoma DisGeNET Curated 2.034E-5 9.885E-4 7.164E-3 1.603E-2 4 217
15 C0376300 Dengue Shock Syndrome DisGeNET BeFree 2.132E-5 9.885E-4 7.164E-3 1.680E-2 2 9
16 C3812396 Chronic idiopathic pulmonary fibrosis DisGeNET BeFree 2.132E-5 9.885E-4 7.164E-3 1.680E-2 2 9
17 C0024530 Malaria DisGeNET Curated 2.133E-5 9.885E-4 7.164E-3 1.680E-2 5 470
18 C0038013 Ankylosing spondylitis DisGeNET Curated 2.264E-5 9.912E-4 7.184E-3 1.784E-2 4 223
19 C0026946 Mycoses DisGeNET BeFree 3.489E-5 1.447E-3 1.049E-2 2.749E-2 4 249
20 C0699949 airway disease DisGeNET BeFree 5.183E-5 2.018E-3 1.462E-2 4.084E-2 3 94
21 C0458219 Complex Regional Pain Syndromes DisGeNET BeFree 5.377E-5 2.018E-3 1.462E-2 4.237E-2 2 14
22 C0850666 helicobacter pylori infection DisGeNET BeFree 8.401E-5 3.009E-3 2.181E-2
6.620E-2
 4 312
23 C0035235 Respiratory Syncytial Virus Infections DisGeNET Curated 8.974E-5 3.075E-3 2.228E-2
7.071E-2
 3 113
24 C0022283 Incontinentia Pigmenti Achromians DisGeNET BeFree 1.237E-4 3.938E-3 2.854E-2
9.747E-2
 2 21
25 C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 1.296E-4 3.938E-3 2.854E-2
1.021E-1
 4 349
26 C0023343 Leprosy DisGeNET Curated 1.299E-4 3.938E-3 2.854E-2
1.024E-1
 3 128
27 C0003165 Anthracosis DisGeNET Curated 1.360E-4 3.969E-3 2.877E-2
1.072E-1
 2 22
28 C0268390 Muckle-Wells Syndrome DisGeNET Curated 1.489E-4 4.190E-3 3.037E-2
1.173E-1
 2 23
29 C0276653 Invasive Pulmonary Aspergillosis DisGeNET BeFree 1.623E-4 4.264E-3 3.090E-2
1.279E-1
 2 24
30 C0206182 Lymphomatoid Papulosis DisGeNET Curated 1.623E-4 4.264E-3 3.090E-2
1.279E-1
 2 24
31 C0034069 Pulmonary Fibrosis DisGeNET Curated 1.710E-4 4.346E-3 3.150E-2
1.347E-1
 4 375
32 C2607914 Allergic rhinitis (disorder) DisGeNET Curated 1.804E-4 4.442E-3 3.219E-2
1.421E-1
 3 143
33 C0040592 Trachoma DisGeNET BeFree 2.062E-4 4.923E-3 3.568E-2
1.625E-1
 2 27
34 C1306759 Eosinophilic disorder DisGeNET BeFree 2.421E-4 5.435E-3 3.939E-2
1.908E-1
 3 158
35 C0011615 Dermatitis, Atopic DisGeNET Curated 2.431E-4 5.435E-3 3.939E-2
1.916E-1
 4 411
36 C0034068 Pulmonary Eosinophilia DisGeNET BeFree 2.552E-4 5.435E-3 3.939E-2
2.011E-1
 2 30
37 C1719495 Aggressive periodontitis, generalized DisGeNET BeFree 2.552E-4 5.435E-3 3.939E-2
2.011E-1
 2 30
38 C0001815 Primary Myelofibrosis DisGeNET Curated 2.653E-4 5.502E-3 3.988E-2
2.091E-1
 3 163
39 C1333762 Gastric Cardia Adenocarcinoma DisGeNET BeFree 2.727E-4 5.509E-3 3.993E-2
2.148E-1
 2 31
40 C0677659 Gastro-esophageal reflux disease with esophagitis DisGeNET BeFree 2.907E-4 5.566E-3 4.034E-2
2.291E-1
 2 32
41 C0014869 Peptic Esophagitis DisGeNET Curated 2.907E-4 5.566E-3 4.034E-2
2.291E-1
 2 32
42 C0375071 Malignant neoplasm of vulva DisGeNET BeFree 3.093E-4 5.566E-3 4.034E-2
2.437E-1
 2 33
43 C0013595 Eczema DisGeNET Curated 3.100E-4 5.566E-3 4.034E-2
2.443E-1
 4 438
44 C0398650 Immune thrombocytopenic purpura DisGeNET Curated 3.108E-4 5.566E-3 4.034E-2
2.449E-1
 3 172
45 C0014457 Eosinophilia DisGeNET Curated 3.437E-4 6.018E-3 4.362E-2
2.708E-1
 3 178
46 C1320214 Invasive Streptococcus pneumoniae disease DisGeNET BeFree 3.686E-4 6.314E-3 4.576E-2
2.904E-1
 2 36
47 C1290884 Inflammatory disorder DisGeNET BeFree 3.972E-4 6.628E-3 4.804E-2
3.130E-1
 3 187
48 C0392164 Pulmonary Cystic Fibrosis DisGeNET BeFree 4.109E-4 6.628E-3 4.804E-2
3.238E-1
 2 38
49 C0030193 Pain DisGeNET Curated 4.122E-4 6.628E-3 4.804E-2
3.248E-1
 4 472
50 C1275126 TNF receptor-associated periodic fever syndrome (TRAPS) DisGeNET Curated 5.266E-4 7.618E-3
5.521E-2
4.150E-1
 2 43
Show 45 more annotations