Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc245_13, positive side

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1: GO: Molecular Function [Display Chart] 13 input genes in category / 90 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances 4.314E-18 2.549E-16 1.296E-15 3.882E-16 9 110
2 GO:0015399 primary active transmembrane transporter activity 8.970E-18 2.549E-16 1.296E-15 8.073E-16 9 119
3 GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity 8.970E-18 2.549E-16 1.296E-15 8.073E-16 9 119
4 GO:0019829 cation-transporting ATPase activity 1.180E-17 2.549E-16 1.296E-15 1.062E-15 8 62
5 GO:0043492 ATPase activity, coupled to movement of substances 1.416E-17 2.549E-16 1.296E-15 1.275E-15 9 125
6 GO:0042625 ATPase coupled ion transmembrane transporter activity 5.243E-17 7.865E-16 3.997E-15 4.719E-15 8 74
7 GO:0015662 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 2.029E-16 2.609E-15 1.326E-14 1.827E-14 7 40
8 GO:0022853 active ion transmembrane transporter activity 6.298E-14 7.085E-13 3.601E-12 5.668E-12 8 175
9 GO:0042623 ATPase activity, coupled 1.077E-13 1.077E-12 5.474E-12 9.692E-12 9 332
10 GO:0022804 active transmembrane transporter activity 2.413E-13 2.172E-12 1.104E-11 2.172E-11 9 363
11 GO:0016887 ATPase activity 1.543E-12 1.263E-11 6.418E-11 1.389E-10 9 446
12 GO:0043682 copper-transporting ATPase activity 4.480E-7 2.983E-6 1.516E-5 4.032E-5 2 2
13 GO:0004008 copper-exporting ATPase activity 4.480E-7 2.983E-6 1.516E-5 4.032E-5 2 2
14 GO:0046961 proton-transporting ATPase activity, rotational mechanism 4.640E-7 2.983E-6 1.516E-5 4.176E-5 3 23
15 GO:0044769 ATPase activity, coupled to transmembrane movement of ions, rotational mechanism 6.021E-7 3.613E-6 1.836E-5 5.419E-5 3 25
16 GO:0036442 proton-exporting ATPase activity 9.550E-7 5.372E-6 2.730E-5 8.595E-5 3 29
17 GO:0046873 metal ion transmembrane transporter activity 6.701E-6 3.355E-5 1.705E-4 6.031E-4 5 426
18 GO:0005375 copper ion transmembrane transporter activity 6.709E-6 3.355E-5 1.705E-4 6.038E-4 2 6
19 GO:0005388 calcium-transporting ATPase activity 2.455E-5 1.163E-4 5.911E-4 2.210E-3 2 11
20 GO:0008553 proton-exporting ATPase activity, phosphorylative mechanism 2.945E-5 1.325E-4 6.736E-4 2.651E-3 2 12
21 GO:0015078 proton transmembrane transporter activity 5.313E-5 2.277E-4 1.157E-3 4.782E-3 3 109
22 GO:0015077 monovalent inorganic cation transmembrane transporter activity 9.939E-5 4.066E-4 2.067E-3 8.945E-3 4 375
23 GO:0046915 transition metal ion transmembrane transporter activity 3.797E-4 1.486E-3 7.552E-3 3.417E-2 2 42
24 GO:0036487 nitric-oxide synthase inhibitor activity 6.966E-4 2.612E-3 1.328E-2
6.270E-2
 1 1
25 GO:0005507 copper ion binding 7.751E-4 2.790E-3 1.418E-2
6.976E-2
 2 60
26 GO:0032767 copper-dependent protein binding 2.089E-3 6.713E-3 3.412E-2
1.880E-1
 1 3
27 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity 2.089E-3 6.713E-3 3.412E-2
1.880E-1
 1 3
28 GO:0016532 superoxide dismutase copper chaperone activity 2.089E-3 6.713E-3 3.412E-2
1.880E-1
 1 3
29 GO:0016508 long-chain-enoyl-CoA hydratase activity 2.784E-3 8.640E-3 4.391E-2
2.505E-1
 1 4
30 GO:0004300 enoyl-CoA hydratase activity 3.479E-3 1.010E-2
5.133E-2
3.131E-1
 1 5
31 GO:0016531 copper chaperone activity 3.479E-3 1.010E-2
5.133E-2
3.131E-1
 1 5
32 GO:0015085 calcium ion transmembrane transporter activity 3.681E-3 1.035E-2
5.261E-2
3.312E-1
 2 132
33 GO:1990239 steroid hormone binding 4.173E-3 1.105E-2
5.614E-2
3.756E-1
 1 6
34 GO:0016530 metallochaperone activity 4.173E-3 1.105E-2
5.614E-2
3.756E-1
 1 6
35 GO:0003988 acetyl-CoA C-acyltransferase activity 4.867E-3 1.252E-2
6.361E-2
4.380E-1
 1 7
36 GO:0072509 divalent inorganic cation transmembrane transporter activity 6.232E-3 1.443E-2
7.335E-2
5.609E-1
 2 173
37 GO:0103116 alpha-D-galactofuranose transporter activity 6.254E-3 1.443E-2
7.335E-2
5.628E-1
 1 9
38 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity 6.254E-3 1.443E-2
7.335E-2
5.628E-1
 1 9
39 GO:0030346 protein phosphatase 2B binding 6.254E-3 1.443E-2
7.335E-2
5.628E-1
 1 9
40 GO:0008494 translation activator activity 6.946E-3 1.488E-2
7.565E-2
6.252E-1
 1 10
41 GO:0005338 nucleotide-sugar transmembrane transporter activity 6.946E-3 1.488E-2
7.565E-2
6.252E-1
 1 10
42 GO:0030235 nitric-oxide synthase regulator activity 6.946E-3 1.488E-2
7.565E-2
6.252E-1
 1 10
43 GO:0005391 sodium:potassium-exchanging ATPase activity 7.638E-3 1.599E-2
8.126E-2
6.875E-1
 1 11
44 GO:0098847 sequence-specific single stranded DNA binding 8.330E-3 1.666E-2
8.468E-2
7.497E-1
 1 12
45 GO:0008556 potassium-transporting ATPase activity 8.330E-3 1.666E-2
8.468E-2
7.497E-1
 1 12
46 GO:0030955 potassium ion binding 1.040E-2 2.035E-2
1.034E-1
9.362E-1
 1 15
47 GO:0031402 sodium ion binding 1.109E-2 2.124E-2
1.080E-1
9.983E-1
 1 16
48 GO:0015215 nucleotide transmembrane transporter activity 1.385E-2 2.596E-2
1.320E-1
1.000E0
 1 20
49 GO:0030506 ankyrin binding 1.454E-2 2.670E-2
1.357E-1
1.000E0
 1 21
50 GO:0050998 nitric-oxide synthase binding 1.522E-2 2.686E-2
1.365E-1
1.000E0
 1 22
Show 45 more annotations

2: GO: Biological Process [Display Chart] 13 input genes in category / 589 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0000041 transition metal ion transport 9.420E-11 5.549E-8 3.860E-7 5.549E-8 6 118
2 GO:0090383 phagosome acidification 2.895E-9 7.576E-7 5.270E-6 1.705E-6 4 28
3 GO:0015988 energy coupled proton transmembrane transport, against electrochemical gradient 5.775E-9 7.576E-7 5.270E-6 3.401E-6 4 33
4 GO:0015991 ATP hydrolysis coupled proton transport 5.775E-9 7.576E-7 5.270E-6 3.401E-6 4 33
5 GO:0030004 cellular monovalent inorganic cation homeostasis 6.742E-9 7.576E-7 5.270E-6 3.971E-6 5 106
6 GO:0033572 transferrin transport 8.303E-9 7.576E-7 5.270E-6 4.890E-6 4 36
7 GO:0090662 ATP hydrolysis coupled transmembrane transport 9.306E-9 7.576E-7 5.270E-6 5.481E-6 4 37
8 GO:0090382 phagosome maturation 1.158E-8 7.576E-7 5.270E-6 6.821E-6 4 39
9 GO:0072512 trivalent inorganic cation transport 1.286E-8 7.576E-7 5.270E-6 7.576E-6 4 40
10 GO:0015682 ferric iron transport 1.286E-8 7.576E-7 5.270E-6 7.576E-6 4 40
11 GO:0051452 intracellular pH reduction 2.730E-8 1.462E-6 1.017E-5 1.608E-5 4 48
12 GO:0045851 pH reduction 3.502E-8 1.719E-6 1.196E-5 2.063E-5 4 51
13 GO:0055067 monovalent inorganic cation homeostasis 5.026E-8 2.277E-6 1.584E-5 2.960E-5 5 158
14 GO:0006826 iron ion transport 7.285E-8 3.065E-6 2.132E-5 4.291E-5 4 61
15 GO:0051453 regulation of intracellular pH 2.083E-7 8.179E-6 5.690E-5 1.227E-4 4 79
16 GO:0030641 regulation of cellular pH 2.305E-7 8.484E-6 5.902E-5 1.357E-4 4 81
17 GO:0060003 copper ion export 4.498E-7 1.559E-5 1.084E-4 2.650E-4 2 2
18 GO:0006885 regulation of pH 5.839E-7 1.911E-5 1.329E-4 3.439E-4 4 102
19 GO:1902600 proton transmembrane transport 7.346E-7 2.277E-5 1.584E-4 4.327E-4 4 108
20 GO:0008286 insulin receptor signaling pathway 1.362E-6 4.012E-5 2.791E-4 8.025E-4 4 126
21 GO:0035434 copper ion transmembrane transport 6.737E-6 1.890E-4 1.314E-3 3.968E-3 2 6
22 GO:0043434 response to peptide hormone 8.097E-6 2.168E-4 1.508E-3 4.769E-3 5 442
23 GO:0032869 cellular response to insulin stimulus 9.989E-6 2.558E-4 1.780E-3 5.884E-3 4 208
24 GO:1901652 response to peptide 1.172E-5 2.877E-4 2.001E-3 6.904E-3 5 477
25 GO:1903779 regulation of cardiac conduction 1.241E-5 2.923E-4 2.033E-3 7.307E-3 3 67
26 GO:0015677 copper ion import 1.615E-5 3.523E-4 2.451E-3 9.512E-3 2 9
27 GO:0098739 import across plasma membrane 1.615E-5 3.523E-4 2.451E-3 9.512E-3 2 9
28 GO:0032868 response to insulin 2.629E-5 5.530E-4 3.847E-3 1.548E-2 4 266
29 GO:0006878 cellular copper ion homeostasis 5.368E-5 1.054E-3 7.332E-3 3.162E-2 2 16
30 GO:0045989 positive regulation of striated muscle contraction 5.368E-5 1.054E-3 7.332E-3 3.162E-2 2 16
31 GO:0071375 cellular response to peptide hormone stimulus 5.680E-5 1.079E-3 7.508E-3 3.346E-2 4 324
32 GO:0055070 copper ion homeostasis 6.839E-5 1.223E-3 8.507E-3 4.028E-2 2 18
33 GO:1901653 cellular response to peptide 6.851E-5 1.223E-3 8.507E-3 4.035E-2 4 340
34 GO:0061337 cardiac conduction 9.240E-5 1.578E-3 1.098E-2
5.442E-2
 3 131
35 GO:0006825 copper ion transport 9.376E-5 1.578E-3 1.098E-2
5.522E-2
 2 21
36 GO:0016241 regulation of macroautophagy 1.610E-4 2.634E-3 1.832E-2
9.483E-2
 3 158
37 GO:0046688 response to copper ion 1.807E-4 2.877E-3 2.001E-2
1.064E-1
 2 29
38 GO:0090075 relaxation of muscle 1.935E-4 3.000E-3 2.087E-2
1.140E-1
 2 30
39 GO:0002026 regulation of the force of heart contraction 2.346E-4 3.543E-3 2.465E-2
1.382E-1
 2 33
40 GO:0032104 regulation of response to extracellular stimulus 2.523E-4 3.624E-3 2.521E-2
1.486E-1
 3 184
41 GO:0032107 regulation of response to nutrient levels 2.523E-4 3.624E-3 2.521E-2
1.486E-1
 3 184
42 GO:0035637 multicellular organismal signaling 3.084E-4 4.324E-3 3.008E-2
1.816E-1
 3 197
43 GO:0090257 regulation of muscle system process 4.205E-4 5.760E-3 4.007E-2
2.477E-1
 3 219
44 GO:0007595 lactation 4.379E-4 5.861E-3 4.077E-2
2.579E-1
 2 45
45 GO:0045933 positive regulation of muscle contraction 4.983E-4 6.522E-3 4.537E-2
2.935E-1
 2 48
46 GO:0046034 ATP metabolic process 5.629E-4 7.054E-3 4.907E-2
3.316E-1
 3 242
47 GO:0008016 regulation of heart contraction 5.629E-4 7.054E-3 4.907E-2
3.316E-1
 3 242
48 GO:0098657 import into cell 6.307E-4 7.213E-3
5.018E-2
3.715E-1
 2 54
49 GO:0033242 negative regulation of cellular amine catabolic process 6.981E-4 7.213E-3
5.018E-2
4.112E-1
 1 1
50 GO:1903249 negative regulation of citrulline biosynthetic process 6.981E-4 7.213E-3
5.018E-2
4.112E-1
 1 1
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 13 input genes in category / 117 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0033176 proton-transporting V-type ATPase complex 1.143E-9 1.338E-7 7.148E-7 1.338E-7 4 23
2 GO:0016469 proton-transporting two-sector ATPase complex 2.489E-8 1.456E-6 7.779E-6 2.912E-6 4 48
3 GO:0098852 lytic vacuole membrane 7.314E-7 2.139E-5 1.143E-4 8.558E-5 5 277
4 GO:0005765 lysosomal membrane 7.314E-7 2.139E-5 1.143E-4 8.558E-5 5 277
5 GO:0033180 proton-transporting V-type ATPase, V1 domain 1.542E-5 3.336E-4 1.783E-3 1.804E-3 2 9
6 GO:0016323 basolateral plasma membrane 1.711E-5 3.336E-4 1.783E-3 2.002E-3 4 244
7 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain 5.806E-5 9.705E-4 5.186E-3 6.793E-3 2 17
8 GO:0030140 trans-Golgi network transport vesicle 1.848E-4 2.702E-3 1.444E-2 2.162E-2 2 30
9 GO:0005802 trans-Golgi network 3.774E-4 4.907E-3 2.622E-2 4.416E-2 3 216
10 GO:0030315 T-tubule 7.433E-4 8.696E-3 4.647E-2
8.696E-2
 2 60
11 GO:0031526 brush border membrane 8.718E-4 9.272E-3 4.955E-2
1.020E-1
 2 65
12 GO:0098791 Golgi subcompartment 1.248E-3 9.778E-3
5.225E-2
1.460E-1
 3 326
13 GO:0036125 fatty acid beta-oxidation multienzyme complex 1.364E-3 9.778E-3
5.225E-2
1.595E-1
 1 2
14 GO:0031673 H zone 1.364E-3 9.778E-3
5.225E-2
1.595E-1
 1 2
15 GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex 1.364E-3 9.778E-3
5.225E-2
1.595E-1
 1 2
16 GO:0032588 trans-Golgi network membrane 1.383E-3 9.778E-3
5.225E-2
1.618E-1
 2 82
17 GO:0031984 organelle subcompartment 1.421E-3 9.778E-3
5.225E-2
1.662E-1
 3 341
18 GO:0005798 Golgi-associated vesicle 1.520E-3 9.877E-3
5.278E-2
1.778E-1
 2 86
19 GO:0005901 caveola 1.888E-3 1.163E-2
6.214E-2
2.210E-1
 2 96
20 GO:0042470 melanosome 2.253E-3 1.198E-2
6.404E-2
2.636E-1
 2 105
21 GO:0048770 pigment granule 2.253E-3 1.198E-2
6.404E-2
2.636E-1
 2 105
22 GO:0044853 plasma membrane raft 2.253E-3 1.198E-2
6.404E-2
2.636E-1
 2 105
23 GO:0045177 apical part of cell 2.719E-3 1.383E-2
7.391E-2
3.181E-1
 3 428
24 GO:0005903 brush border 3.376E-3 1.646E-2
8.795E-2
3.950E-1
 2 129
25 GO:0031674 I band 3.690E-3 1.727E-2
9.229E-2
4.318E-1
 2 135
26 GO:0030121 AP-1 adaptor complex 4.086E-3 1.770E-2
9.461E-2
4.780E-1
 1 6
27 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain 4.086E-3 1.770E-2
9.461E-2
4.780E-1
 1 6
28 GO:0042383 sarcolemma 4.652E-3 1.944E-2
1.039E-1
5.442E-1
 2 152
29 GO:0030666 endocytic vesicle membrane 4.893E-3 1.974E-2
1.055E-1
5.725E-1
 2 156
30 GO:0030136 clathrin-coated vesicle 5.266E-3 2.054E-2
1.097E-1
6.161E-1
 2 162
31 GO:0098862 cluster of actin-based cell projections 6.117E-3 2.239E-2
1.196E-1
7.157E-1
 2 175
32 GO:0031095 platelet dense tubular network membrane 6.123E-3 2.239E-2
1.196E-1
7.164E-1
 1 9
33 GO:0033179 proton-transporting V-type ATPase, V0 domain 6.801E-3 2.411E-2
1.288E-1
7.957E-1
 1 10
34 GO:0005890 sodium:potassium-exchanging ATPase complex 7.479E-3 2.500E-2
1.336E-1
8.750E-1
 1 11
35 GO:0031094 platelet dense tubular network 7.479E-3 2.500E-2
1.336E-1
8.750E-1
 1 11
36 GO:0030017 sarcomere 7.767E-3 2.511E-2
1.342E-1
9.087E-1
 2 198
37 GO:0043209 myelin sheath 8.072E-3 2.511E-2
1.342E-1
9.444E-1
 2 202
38 GO:0030130 clathrin coat of trans-Golgi network vesicle 8.156E-3 2.511E-2
1.342E-1
9.542E-1
 1 12
39 GO:0044449 contractile fiber part 9.102E-3 2.715E-2
1.451E-1
1.000E0
 2 215
40 GO:0016471 vacuolar proton-transporting V-type ATPase complex 9.509E-3 2.715E-2
1.451E-1
1.000E0
 1 14
41 GO:0030016 myofibril 9.512E-3 2.715E-2
1.451E-1
1.000E0
 2 220
42 GO:0005770 late endosome 9.847E-3 2.743E-2
1.466E-1
1.000E0
 2 224
43 GO:0012510 trans-Golgi network transport vesicle membrane 1.019E-2 2.771E-2
1.481E-1
1.000E0
 1 15
44 GO:0043292 contractile fiber 1.071E-2 2.824E-2
1.509E-1
1.000E0
 2 234
45 GO:0090533 cation-transporting ATPase complex 1.086E-2 2.824E-2
1.509E-1
1.000E0
 1 16
46 GO:0030135 coated vesicle 1.133E-2 2.881E-2
1.540E-1
1.000E0
 2 241
47 GO:0030139 endocytic vesicle 1.358E-2 3.380E-2
1.806E-1
1.000E0
 2 265
48 GO:0033177 proton-transporting two-sector ATPase complex, proton-transporting domain 1.558E-2 3.720E-2
1.988E-1
1.000E0
 1 23
49 GO:0097228 sperm principal piece 1.558E-2 3.720E-2
1.988E-1
1.000E0
 1 23
50 GO:0098533 ATPase dependent transmembrane transport complex 1.625E-2 3.803E-2
2.032E-1
1.000E0
 1 24
Show 45 more annotations

4: Human Phenotype [Display Chart] 8 input genes in category / 878 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0011967 Hypocupremia 1.514E-5 1.330E-2
9.779E-2
 1.330E-2 2 4
2 HP:0010837 Decreased serum ceruloplasmin 5.286E-5 2.321E-2
1.707E-1
 4.642E-2 2 7
3 HP:0010836 Abnormality of copper homeostasis 9.047E-5 2.648E-2
1.948E-1
7.943E-2
 2 9

5: Mouse Phenotype [Display Chart] 12 input genes in category / 382 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0010243 increased kidney copper level 1.231E-6 4.703E-4 3.068E-3 4.703E-4 2 2
2 MP:0010242 abnormal kidney copper level 3.691E-6 7.050E-4 4.599E-3 1.410E-3 2 3
3 MP:0006349 decreased circulating copper level 7.377E-6 7.823E-4 5.104E-3 2.818E-3 2 4
4 MP:0011213 abnormal brain copper level 1.229E-5 7.823E-4 5.104E-3 4.694E-3 2 5
5 MP:0006348 abnormal circulating copper level 1.229E-5 7.823E-4 5.104E-3 4.694E-3 2 5
6 MP:0003067 decreased liver copper level 1.229E-5 7.823E-4 5.104E-3 4.694E-3 2 5
7 MP:0003065 abnormal liver copper level 5.512E-5 3.008E-3 1.962E-2 2.105E-2 2 10
8 MP:0003952 abnormal copper level 8.074E-5 3.855E-3 2.515E-2 3.084E-2 2 12
9 MP:0003951 abnormal copper homeostasis 9.535E-5 4.047E-3 2.640E-2 3.642E-2 2 13
10 MP:0001274 curly vibrissae 3.940E-4 1.505E-2
9.819E-2
1.505E-1
 2 26
11 MP:0000738 impaired muscle contractility 4.689E-4 1.628E-2
1.062E-1
1.791E-1
 4 342
12 MP:0010247 increased intestine copper level 1.159E-3 3.405E-2
2.222E-1
4.427E-1
 1 1
13 MP:0002845 abnormal aortic weight 1.159E-3 3.405E-2
2.222E-1
4.427E-1
 1 1
14 MP:0005620 abnormal muscle contractility 1.275E-3 3.480E-2
2.270E-1
4.871E-1
 4 446
15 MP:0006350 increased circulating copper level 2.316E-3 4.424E-2
2.887E-1
8.849E-1
 1 2
16 MP:0010246 abnormal intestine copper level 2.316E-3 4.424E-2
2.887E-1
8.849E-1
 1 2
17 MP:0011214 increased brain copper level 2.316E-3 4.424E-2
2.887E-1
8.849E-1
 1 2
18 MP:0012661 decreased circulating ceruloplasmin level 2.316E-3 4.424E-2
2.887E-1
8.849E-1
 1 2
19 MP:0011351 absent proximal convoluted tubule brush border 2.316E-3 4.424E-2
2.887E-1
8.849E-1
 1 2
20 MP:0003907 decreased aorta elastin content 2.316E-3 4.424E-2
2.887E-1
8.849E-1
 1 2
Show 15 more annotations

6: Domain [Display Chart] 13 input genes in category / 77 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR023299 ATPase P-typ cyto domN InterPro 2.150E-11 3.703E-10 1.824E-9 1.656E-9 5 35
2 IPR001757 P typ ATPase InterPro 2.496E-11 3.703E-10 1.824E-9 1.922E-9 5 36
3 PS00154 ATPASE E1 E2 PROSITE 2.496E-11 3.703E-10 1.824E-9 1.922E-9 5 36
4 IPR018303 ATPase P-typ P site InterPro 2.496E-11 3.703E-10 1.824E-9 1.922E-9 5 36
5 PF00122 E1-E2 ATPase Pfam 2.885E-11 3.703E-10 1.824E-9 2.222E-9 5 37
6 IPR008250 ATPase P-typ transduc dom A InterPro 2.885E-11 3.703E-10 1.824E-9 2.222E-9 5 37
7 IPR023214 HAD-like dom InterPro 1.470E-9 1.616E-8 7.965E-8 1.132E-7 5 79
8 3.40.1110.10 - Gene3D 4.957E-9 4.241E-8 2.090E-7 3.817E-7 4 32
9 2.70.150.10 - Gene3D 4.957E-9 4.241E-8 2.090E-7 3.817E-7 4 32
10 1.20.1110.10 - Gene3D 1.454E-7 1.018E-6 5.015E-6 1.120E-5 3 16
11 IPR023298 ATPase P-typ TM dom InterPro 1.454E-7 1.018E-6 5.015E-6 1.120E-5 3 16
12 IPR006068 ATPase P-typ cation-transptr C InterPro 1.765E-7 1.045E-6 5.151E-6 1.359E-5 3 17
13 PF00689 Cation ATPase C Pfam 1.765E-7 1.045E-6 5.151E-6 1.359E-5 3 17
14 SM00831 Cation ATPase N SMART 2.117E-7 1.087E-6 5.355E-6 1.630E-5 3 18
15 PF00690 Cation ATPase N Pfam 2.117E-7 1.087E-6 5.355E-6 1.630E-5 3 18
16 IPR004014 ATPase P-typ cation-transptr N InterPro 2.513E-7 1.209E-6 5.959E-6 1.935E-5 3 19
17 IPR006122 HMA Cu ion-bd InterPro 4.445E-7 1.901E-6 9.369E-6 3.422E-5 2 2
18 IPR027256 P-typ ATPase IB InterPro 4.445E-7 1.901E-6 9.369E-6 3.422E-5 2 2
19 IPR017969 Heavy-metal-associated CS InterPro 1.333E-6 5.402E-6 2.662E-5 1.026E-4 2 3
20 PF00403 HMA Pfam 2.665E-6 9.327E-6 4.596E-5 2.052E-4 2 4
21 PS50846 HMA 2 PROSITE 2.665E-6 9.327E-6 4.596E-5 2.052E-4 2 4
22 PS01047 HMA 1 PROSITE 2.665E-6 9.327E-6 4.596E-5 2.052E-4 2 4
23 IPR006121 HMA dom InterPro 9.316E-6 3.119E-5 1.537E-4 7.173E-4 2 7
24 PF07850 Renin r Pfam 6.939E-4 1.908E-3 9.403E-3
5.343E-2
 1 1
25 PF01813 ATP-synt D Pfam 6.939E-4 1.908E-3 9.403E-3
5.343E-2
 1 1
26 IPR012493 Renin rcpt InterPro 6.939E-4 1.908E-3 9.403E-3
5.343E-2
 1 1
27 IPR030332 SERCA1 InterPro 6.939E-4 1.908E-3 9.403E-3
5.343E-2
 1 1
28 IPR002699 V ATPase D InterPro 6.939E-4 1.908E-3 9.403E-3
5.343E-2
 1 1
29 3.40.50.1000 - Gene3D 8.746E-4 2.322E-3 1.144E-2
6.734E-2
 2 64
30 IPR030319 ATP2B1/4 InterPro 1.387E-3 3.142E-3 1.548E-2
1.068E-1
 1 2
31 IPR005723 ATPase V1-cplx bsu InterPro 1.387E-3 3.142E-3 1.548E-2
1.068E-1
 1 2
32 IPR022879 V-ATPase su B/beta InterPro 1.387E-3 3.142E-3 1.548E-2
1.068E-1
 1 2
33 PF03223 V-ATPase C Pfam 1.387E-3 3.142E-3 1.548E-2
1.068E-1
 1 2
34 IPR004907 ATPase V1-cplx csu InterPro 1.387E-3 3.142E-3 1.548E-2
1.068E-1
 1 2
35 IPR005782 P-type ATPase IIA InterPro 2.080E-3 4.577E-3 2.255E-2
1.602E-1
 1 3
36 IPR006408 P-type ATPase IIB InterPro 2.773E-3 5.208E-3 2.566E-2
2.135E-1
 1 4
37 IPR002490 V-ATPase 116kDa su InterPro 2.773E-3 5.208E-3 2.566E-2
2.135E-1
 1 4
38 IPR022141 ATP Ca trans C InterPro 2.773E-3 5.208E-3 2.566E-2
2.135E-1
 1 4
39 PF01496 V ATPase I Pfam 2.773E-3 5.208E-3 2.566E-2
2.135E-1
 1 4
40 PF12424 ATP Ca trans C Pfam 2.773E-3 5.208E-3 2.566E-2
2.135E-1
 1 4
41 IPR026028 V-type ATPase 116kDa su euka InterPro 2.773E-3 5.208E-3 2.566E-2
2.135E-1
 1 4
42 IPR020615 Thiolase acyl enz int AS InterPro 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
43 IPR020610 Thiolase AS InterPro 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
44 PS00152 ATPASE ALPHA BETA PROSITE 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
45 IPR000793 ATP synth asu C InterPro 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
46 IPR020003 ATPase a/bsu AS InterPro 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
47 IPR004100 ATPase F1/V1/A1 a/bsu N InterPro 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
48 PF02874 ATP-synt ab N Pfam 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
49 PF00006 ATP-synt ab Pfam 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
50 PF00306 ATP-synt ab C Pfam 3.465E-3 5.247E-3 2.585E-2
2.668E-1
 1 5
Show 45 more annotations

7: Pathway [Display Chart] 13 input genes in category / 164 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269950 Ion channel transport BioSystems: REACTOME 6.014E-14 9.864E-12 5.603E-11 9.864E-12 9 209
2 MAP00190 Oxidative phosphorylation MAP00190 Oxidative phosphorylation GenMAPP 2.302E-12 1.888E-10 1.072E-9 3.776E-10 6 44
3 1269951 Ion transport by P-type ATPases BioSystems: REACTOME 2.301E-9 9.006E-8 5.116E-7 3.774E-7 5 58
4 MAP03070 Type III secretion system MAP03070 Type III secretion system GenMAPP 2.746E-9 9.006E-8 5.116E-7 4.503E-7 4 19
5 MAP00193 ATP synthesis MAP00193 ATP synthesis GenMAPP 2.746E-9 9.006E-8 5.116E-7 4.503E-7 4 19
6 MAP00195 Photosynthesis MAP00195 Photosynthesis GenMAPP 3.430E-9 9.376E-8 5.326E-7 5.626E-7 4 20
7 1269442 Insulin receptor recycling BioSystems: REACTOME 1.237E-8 2.537E-7 1.441E-6 2.029E-6 4 27
8 147586 Collecting duct acid secretion BioSystems: KEGG 1.237E-8 2.537E-7 1.441E-6 2.029E-6 4 27
9 1269949 Transferrin endocytosis and recycling BioSystems: REACTOME 1.929E-8 3.515E-7 1.997E-6 3.164E-6 4 30
10 1269138 ROS, RNS production in phagocytes BioSystems: REACTOME 2.875E-8 4.716E-7 2.679E-6 4.716E-6 4 33
11 1269948 Iron uptake and transport BioSystems: REACTOME 9.478E-8 1.413E-6 8.027E-6 1.554E-5 4 44
12 83101 Vibrio cholerae infection BioSystems: KEGG 1.738E-7 2.375E-6 1.349E-5 2.850E-5 4 51
13 373900 Synaptic vesicle cycle BioSystems: KEGG 4.113E-7 5.189E-6 2.948E-5 6.746E-5 4 63
14 83102 Epithelial cell signaling in Helicobacter pylori infection BioSystems: KEGG 5.608E-7 6.569E-6 3.731E-5 9.196E-5 4 68
15 200309 Rheumatoid arthritis BioSystems: KEGG 1.737E-6 1.899E-5 1.079E-4 2.849E-4 4 90
16 82942 Oxidative phosphorylation BioSystems: KEGG 8.260E-6 8.466E-5 4.809E-4 1.355E-3 4 133
17 153910 Phagosome BioSystems: KEGG 1.476E-5 1.424E-4 8.087E-4 2.420E-3 4 154
18 1339121 Ion homeostasis BioSystems: REACTOME 2.388E-5 2.176E-4 1.236E-3 3.916E-3 3 56
19 PW:0000035 ATP synthetic Pathway Ontology 6.604E-5 5.700E-4 3.238E-3 1.083E-2 2 12
20 1269347 Reduction of cytosolic Ca++ levels BioSystems: REACTOME 9.095E-5 7.458E-4 4.236E-3 1.492E-2 2 14
21 169306 Pancreatic secretion BioSystems: KEGG 1.201E-4 9.383E-4 5.330E-3 1.970E-2 3 96
22 1269428 Signaling by Insulin receptor BioSystems: REACTOME 2.737E-4 2.040E-3 1.159E-2 4.488E-2 4 326
23 1339115 Cardiac conduction BioSystems: REACTOME 3.821E-4 2.724E-3 1.547E-2
6.266E-2
 3 142
24 83059 mTOR signaling pathway BioSystems: KEGG 4.575E-4 3.018E-3 1.714E-2
7.503E-2
 3 151
25 1269345 Platelet calcium homeostasis BioSystems: REACTOME 4.601E-4 3.018E-3 1.714E-2
7.546E-2
 2 31
26 983748 cGMP-PKG signaling pathway BioSystems: KEGG 5.722E-4 3.609E-3 2.050E-2
9.384E-2
 3 163
27 1269868 Muscle contraction BioSystems: REACTOME 1.098E-3 6.671E-3 3.789E-2
1.801E-1
 3 204
28 212237 Mineral absorption BioSystems: KEGG 1.247E-3 7.303E-3 4.148E-2
2.045E-1
 2 51
29 1404797 Platinum drug resistance BioSystems: KEGG 2.537E-3 1.435E-2
8.149E-2
4.160E-1
 2 73
30 1270017 Beta oxidation of palmitoyl-CoA to myristoyl-CoA BioSystems: REACTOME 3.130E-3 1.656E-2
9.404E-2
5.132E-1
 1 3
31 1270018 Beta oxidation of myristoyl-CoA to lauroyl-CoA BioSystems: REACTOME 3.130E-3 1.656E-2
9.404E-2
5.132E-1
 1 3
32 153376 Salivary secretion BioSystems: KEGG 3.828E-3 1.944E-2
1.104E-1
6.277E-1
 2 90
33 1269341 Platelet homeostasis BioSystems: REACTOME 3.911E-3 1.944E-2
1.104E-1
6.414E-1
 2 91
34 1457779 Ion influx/efflux at host-pathogen interface BioSystems: REACTOME 4.171E-3 2.012E-2
1.143E-1
6.840E-1
 1 4
35 1270022 Beta oxidation of hexanoyl-CoA to butanoyl-CoA BioSystems: REACTOME 5.211E-3 2.249E-2
1.277E-1
8.546E-1
 1 5
36 1270019 Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA BioSystems: REACTOME 5.211E-3 2.249E-2
1.277E-1
8.546E-1
 1 5
37 1270021 Beta oxidation of octanoyl-CoA to hexanoyl-CoA BioSystems: REACTOME 5.211E-3 2.249E-2
1.277E-1
8.546E-1
 1 5
38 1270020 Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA BioSystems: REACTOME 5.211E-3 2.249E-2
1.277E-1
8.546E-1
 1 5
39 1270071 Acyl chain remodeling of CL BioSystems: REACTOME 6.250E-3 2.500E-2
1.420E-1
1.000E0
 1 6
40 1270024 mitochondrial fatty acid beta-oxidation of unsaturated fatty acids BioSystems: REACTOME 6.250E-3 2.500E-2
1.420E-1
1.000E0
 1 6
41 413380 Fatty acid biosynthesis, elongation, mitochondria BioSystems: KEGG 6.250E-3 2.500E-2
1.420E-1
1.000E0
 1 6
42 99052 Lysosome BioSystems: KEGG 7.033E-3 2.533E-2
1.439E-1
1.000E0
 2 123
43 SMP00054 Fatty Acid Elongation In Mitochondria SMPDB 7.288E-3 2.533E-2
1.439E-1
1.000E0
 1 7
44 MAP00062 Fatty acid biosynthesis path 2 MAP00062 Fatty acid biosynthesis path 2 GenMAPP 7.288E-3 2.533E-2
1.439E-1
1.000E0
 1 7
45 SMP00186 Glutaric Aciduria Type III SMPDB 9.361E-3 2.533E-2
1.439E-1
1.000E0
 1 9
46 SMP00037 Lysine Degradation SMPDB 9.361E-3 2.533E-2
1.439E-1
1.000E0
 1 9
47 908257 Adrenergic signaling in cardiomyocytes BioSystems: KEGG 9.532E-3 2.533E-2
1.439E-1
1.000E0
 2 144
48 SMP00397 Levobupivacaine Pathway SMPDB 1.040E-2 2.533E-2
1.439E-1
1.000E0
 1 10
49 SMP00402 Procaine Pathway SMPDB 1.040E-2 2.533E-2
1.439E-1
1.000E0
 1 10
50 SMP00394 Chloroprocaine Pathway SMPDB 1.040E-2 2.533E-2
1.439E-1
1.000E0
 1 10
Show 45 more annotations

8: Pubmed [Display Chart] 13 input genes in category / 1635 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 15071553 Biology, structure and mechanism of P-type ATPases. Pubmed 2.248E-13 3.675E-10 2.932E-9 3.675E-10 5 29
2 10221984 Vacuolar and plasma membrane proton-adenosinetriphosphatases. Pubmed 2.462E-11 6.371E-9 5.082E-8 4.025E-8 4 18
3 10440860 Animal plasma membrane energization by proton-motive V-ATPases. Pubmed 2.462E-11 6.371E-9 5.082E-8 4.025E-8 4 18
4 9210392 The vacuolar H+-ATPase: a universal proton pump of eukaryotes. Pubmed 2.462E-11 6.371E-9 5.082E-8 4.025E-8 4 18
5 10224039 Structure and properties of the vacuolar (H+)-ATPases. Pubmed 2.462E-11 6.371E-9 5.082E-8 4.025E-8 4 18
6 10340843 Introduction: V-ATPases 1992-1998. Pubmed 2.462E-11 6.371E-9 5.082E-8 4.025E-8 4 18
7 16177003 Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. Pubmed 3.117E-11 6.371E-9 5.082E-8 5.097E-8 4 19
8 9442887 Structure, function and regulation of the vacuolar (H+)-ATPase. Pubmed 3.117E-11 6.371E-9 5.082E-8 5.097E-8 4 19
9 14597263 Neurotransmitter release: the dark side of the vacuolar-H+ATPase. Pubmed 5.880E-11 7.395E-9 5.899E-8 9.614E-8 4 22
10 14580332 Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes. Pubmed 5.880E-11 7.395E-9 5.899E-8 9.614E-8 4 22
11 17662945 Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation. Pubmed 5.880E-11 7.395E-9 5.899E-8 9.614E-8 4 22
12 12788495 Proton translocation driven by ATP hydrolysis in V-ATPases. Pubmed 5.880E-11 7.395E-9 5.899E-8 9.614E-8 4 22
13 11836511 The vacuolar (H+)-ATPases--nature's most versatile proton pumps. Pubmed 5.880E-11 7.395E-9 5.899E-8 9.614E-8 4 22
14 2874839 Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor. Pubmed 1.016E-10 1.187E-8 9.468E-8 1.662E-7 4 25
15 22982048 Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts. Pubmed 3.500E-8 3.815E-6 3.043E-5 5.722E-5 3 20
16 17897319 Integral and associated lysosomal membrane proteins. Pubmed 7.889E-8 4.265E-6 3.402E-5 1.290E-4 4 126
17 12539960 Copper transporting P-type ATPases and human disease. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
18 9823011 Genes regulating copper metabolism. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
19 27896900 Molecular features of copper binding proteins involved in copper homeostasis. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
20 21117320 [Structure and function of ATP7A and ATP7B proteins--Cu-transporting ATPases]. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
21 19645496 Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
22 8732640 Menkes disease: recent advances and new insights into copper metabolism. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
23 28820536 Atp7a and Atp7b regulate copper homeostasis in developing male germ cells in mice. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
24 8082762 Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
25 15135234 Expression and localization of menkes and Wilson copper transporting ATPases in human placenta. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
26 18000748 Copper-transporting ATPases ATP7A and ATP7B: cousins, not twins. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
27 17531189 Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
28 12372948 Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
29 17109627 Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
30 17717039 Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
31 28271598 Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
32 17562324 Biochemical basis of regulation of human copper-transporting ATPases. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
33 28164426 Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
34 18565219 Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
35 21115196 Differential intracellular localisation of the Menkes and Wilson copper transporting ATPases in the third trimester human placenta. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
36 20045993 Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
37 9392450 Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
38 9215673 Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
39 17928409 Intracellular targeting of copper-transporting ATPase ATP7A in a normal and Atp7b-/- kidney. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
40 19046832 [From gene to disease: copper-transporting P ATPases alteration]. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
41 18688737 Quantitative relationship between mutated amino-acid sequence of human copper-transporting ATPases and their related diseases. Pubmed 1.069E-7 4.265E-6 3.402E-5 1.749E-4 2 2
42 19199708 Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). Pubmed 1.793E-7 6.978E-6 5.567E-5 2.931E-4 5 416
43 23798571 Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability. Pubmed 2.059E-7 7.830E-6 6.246E-5 3.367E-4 4 160
44 10557326 Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
45 23963605 Intestinal expression of metal transporters in Wilson's disease. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
46 28737129 Association between polymorphisms in CTR1, CTR2, ATP7A, and ATP7B and platinum resistance in epithelial ovarian cancer. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
47 15634671 The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
48 21242307 Clusterin (apolipoprotein J), a molecular chaperone that facilitates degradation of the copper-ATPases ATP7A and ATP7B. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
49 23751120 Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
50 10497213 Characterization of the interaction between the Wilson and Menkes disease proteins and the cytoplasmic copper chaperone, HAH1p. Pubmed 3.208E-7 9.896E-6 7.894E-5 5.245E-4 2 3
Show 45 more annotations

9: Interaction [Display Chart] 13 input genes in category / 920 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:TLDC2 TLDC2 interactions 1.081E-8 9.944E-6 7.361E-5 9.944E-6 3 7
2 int:ATP6V0A2 ATP6V0A2 interactions 7.254E-8 3.337E-5 2.470E-4 6.674E-5 4 58
3 int:ATP6V1E1 ATP6V1E1 interactions 1.154E-7 3.540E-5 2.620E-4 1.062E-4 4 65
4 int:ATP6V1B1 ATP6V1B1 interactions 6.076E-7 1.081E-4 8.001E-4 5.590E-4 4 98
5 int:ATP6V1A ATP6V1A interactions 6.859E-7 1.081E-4 8.001E-4 6.311E-4 4 101
6 int:ATP6V1C2 ATP6V1C2 interactions 7.049E-7 1.081E-4 8.001E-4 6.485E-4 3 25
7 int:ATP6AP2 ATP6AP2 interactions 1.002E-6 1.317E-4 9.749E-4 9.219E-4 4 111
8 int:ATP6V0D1 ATP6V0D1 interactions 1.196E-6 1.375E-4 1.018E-3 1.100E-3 4 116
9 int:ATP6V1D ATP6V1D interactions 6.312E-6 6.453E-4 4.776E-3 5.807E-3 3 51
10 int:ATP6V1F ATP6V1F interactions 8.385E-6 7.714E-4 5.710E-3 7.714E-3 3 56
11 int:ADRB2 ADRB2 interactions 2.929E-5 2.449E-3 1.813E-2 2.694E-2 4 260
12 int:UBE2L6 UBE2L6 interactions 4.519E-5 3.465E-3 2.565E-2 4.158E-2 3 98
13 int:ATP6V1B2 ATP6V1B2 interactions 5.397E-5 3.820E-3 2.827E-2 4.965E-2 3 104
14 int:ATOX1 ATOX1 interactions 5.939E-5 3.903E-3 2.889E-2
5.464E-2
 2 16
15 int:ITM2A ITM2A interactions 6.728E-5 4.127E-3 3.055E-2
6.190E-2
 2 17
16 int:FXYD1 FXYD1 interactions 9.388E-5 5.301E-3 3.924E-2
8.637E-2
 2 20
17 int:ATP6V0D2 ATP6V0D2 interactions 1.037E-4 5.301E-3 3.924E-2
9.542E-2
 2 21
18 int:PDZD11 PDZD11 interactions 1.037E-4 5.301E-3 3.924E-2
9.542E-2
 2 21
19 int:TCIRG1 TCIRG1 interactions 1.140E-4 5.522E-3 4.088E-2
1.049E-1
 2 22
20 int:GLRX GLRX interactions 1.361E-4 6.263E-3 4.636E-2
1.253E-1
 2 24
21 int:TMEM17 TMEM17 interactions 1.577E-4 6.699E-3 4.958E-2
1.451E-1
 4 401
22 int:GPC1 GPC1 interactions 1.602E-4 6.699E-3 4.958E-2
1.474E-1
 2 26
23 int:LAMTOR2 LAMTOR2 interactions 1.729E-4 6.917E-3
5.120E-2
1.591E-1
 2 27
24 int:ATP1A1 ATP1A1 interactions 2.483E-4 9.517E-3
7.044E-2
2.284E-1
 3 174
25 int:GOLT1B GOLT1B interactions 3.117E-4 1.147E-2
8.490E-2
2.867E-1
 3 188
26 int:ATP6V1G1 ATP6V1G1 interactions 3.633E-4 1.285E-2
9.515E-2
3.342E-1
 2 39
27 int:DNAJB2 DNAJB2 interactions 5.059E-4 1.724E-2
1.276E-1
4.654E-1
 2 46
28 int:ATF2 ATF2 interactions 5.411E-4 1.778E-2
1.316E-1
4.978E-1
 3 227
29 int:CIAPIN1 CIAPIN1 interactions 5.978E-4 1.833E-2
1.357E-1
5.500E-1
 2 50
30 int:ATP6AP1 ATP6AP1 interactions 5.978E-4 1.833E-2
1.357E-1
5.500E-1
 2 50
31 int:CPT1A CPT1A interactions 6.219E-4 1.846E-2
1.366E-1
5.722E-1
 2 51
32 int:LAMTOR5 LAMTOR5 interactions 6.716E-4 1.931E-2
1.429E-1
6.179E-1
 2 53
33 int:ATP6V1H ATP6V1H interactions 7.232E-4 2.016E-2
1.492E-1
6.653E-1
 2 55
34 int:ATP2B4 ATP2B4 interactions 8.890E-4 2.405E-2
1.781E-1
8.179E-1
 2 61
35 int:RAB14 RAB14 interactions 9.182E-4 2.414E-2
1.787E-1
8.448E-1
 2 62
36 int:ATP6V1C1 ATP6V1C1 interactions 9.479E-4 2.423E-2
1.793E-1
8.721E-1
 2 63
37 int:SEC31A SEC31A interactions 1.040E-3 2.586E-2
1.914E-1
9.567E-1
 2 66
38 int:UBAC2 UBAC2 interactions 1.136E-3 2.707E-2
2.004E-1
1.000E0
 2 69
39 int:UNK UNK interactions 1.192E-3 2.707E-2
2.004E-1
1.000E0
 3 298
40 int:MRPL40 MRPL40 interactions 1.202E-3 2.707E-2
2.004E-1
1.000E0
 2 71
41 int:PCDHGB1 PCDHGB1 interactions 1.236E-3 2.707E-2
2.004E-1
1.000E0
 2 72
42 int:PFKM PFKM interactions 1.236E-3 2.707E-2
2.004E-1
1.000E0
 2 72
43 int:ATP6V0A1 ATP6V0A1 interactions 1.305E-3 2.789E-2
2.065E-1
1.000E0
 2 74
44 int:COMMD1 COMMD1 interactions 1.340E-3 2.789E-2
2.065E-1
1.000E0
 2 75
45 int:CLEC2D CLEC2D interactions 1.376E-3 2.789E-2
2.065E-1
1.000E0
 2 76
46 int:IQCB1 IQCB1 interactions 1.437E-3 2.789E-2
2.065E-1
1.000E0
 3 318
47 int:NUDT11 NUDT11 interactions 1.468E-3 2.789E-2
2.065E-1
1.000E0
 1 2
48 int:FXYD2 FXYD2 interactions 1.468E-3 2.789E-2
2.065E-1
1.000E0
 1 2
49 int:LGALS9 LGALS9 interactions 1.486E-3 2.789E-2
2.065E-1
1.000E0
 2 79
50 int:COG6 COG6 interactions 1.523E-3 2.802E-2
2.074E-1
1.000E0
 2 80
Show 45 more annotations

10: Cytoband [Display Chart] 13 input genes in category / 13 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 14q23-q24.2 14q23-q24.2 1.125E-3 9.747E-3 3.100E-2 1.462E-2 1 3
2 2p13-p12 2p13-p12 1.499E-3 9.747E-3 3.100E-2 1.949E-2 1 4
3 2p23 2p23 6.358E-3 1.985E-2
6.313E-2
8.266E-2
 1 17
4 16p12.1 16p12.1 9.338E-3 1.985E-2
6.313E-2
1.214E-1
 1 25
5 1p21 1p21 9.338E-3 1.985E-2
6.313E-2
1.214E-1
 1 25
6 Xq21.1 Xq21.1 1.305E-2 1.985E-2
6.313E-2
1.697E-1
 1 35
7 Xp11.4 Xp11.4 1.379E-2 1.985E-2
6.313E-2
1.793E-1
 1 37
8 8p21.3 8p21.3 1.453E-2 1.985E-2
6.313E-2
1.889E-1
 1 39
9 8q22.3 8q22.3 1.453E-2 1.985E-2
6.313E-2
1.889E-1
 1 39
10 13q14.3 13q14.3 1.527E-2 1.985E-2
6.313E-2
1.985E-1
 1 41
11 1q32.1 1q32.1 4.193E-2 4.621E-2
1.469E-1
5.451E-1
 1 114
12 7q22.1 7q22.1 4.265E-2 4.621E-2
1.469E-1
5.545E-1
 1 116
Show 7 more annotations

11: Transcription Factor Binding Site [Display Chart] 12 input genes in category / 73 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 9 input genes in category / 4 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 415 V-type ATPases genenames.org 2.434E-10 9.737E-10 2.029E-9 9.737E-10 4 23
2 1212 ATPase copper transporting genenames.org 2.175E-7 4.350E-7 9.063E-7 8.701E-7 2 2
3 1209 ATPases Ca2+ transporting genenames.org 7.817E-6 1.042E-5 2.171E-5 3.127E-5 2 9
4 1208 ATPase Na+/K+ transporting subunits genenames.org 3.458E-3 3.458E-3 7.204E-3 1.383E-2 1 7

13: Coexpression [Display Chart] 13 input genes in category / 1185 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M4461 Genes down-regulated in comparison of monocytes cultured for 0 days versus those cultured for 7 days. MSigDB C7: Immunologic Signatures (v6.0) 3.645E-6 4.319E-3 3.306E-2 4.319E-3 4 200
2 19658189-TableS8d Human EmbryonicStemCell Xu09 85genes GeneSigDB 1.241E-5 7.350E-3
5.627E-2
 1.470E-2 3 83
3 M1885 Genes down-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.934E-5 1.268E-2
9.707E-2
 4.662E-2 4 366
4 M1865 Up-regulated genes in the subpopulation of invasive PyMT cells (breast cancer) compared to the general population of PyMT cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.280E-5 1.268E-2
9.707E-2
5.072E-2
 4 374
5 M6041 'Cancer prone response profile' (CPRP): genes changed in response to estradiol [PubChem=5757] in epithelial cell cultures from patients at high risk of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.093E-4 1.839E-2
1.408E-1
1.295E-1
 2 28
6 20460173-ImmPortMemoryvsNaive Human Immune Kong10 36genes ImmPort MemoryvsNaive GeneSigDB 1.173E-4 1.839E-2
1.408E-1
1.390E-1
 2 29
7 M8491 Genes up-regulated in B16 melanoma at day 3 of adoptive transfer treatment: mock versus therapy. MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 1.839E-2
1.408E-1
2.023E-1
 3 200
8 M9491 Genes up-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: effectors at day 8 versus exhausted at day 30. MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 1.839E-2
1.408E-1
2.023E-1
 3 200
9 M5936 Genes encoding proteins involved in oxidative phosphorylation. MSigDB H: Hallmark Gene Sets (v6.0) 1.707E-4 1.839E-2
1.408E-1
2.023E-1
 3 200
10 M8539 Genes up-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820]. MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 1.839E-2
1.408E-1
2.023E-1
 3 200
11 M4503 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulatd dendritic cells (DC). MSigDB C7: Immunologic Signatures (v6.0) 1.707E-4 1.839E-2
1.408E-1
2.023E-1
 3 200
12 20371479-TableS2 Human Leukemia Saito10 259genes GeneSigDB 3.064E-4 3.026E-2
2.316E-1
3.631E-1
 3 244
13 M16977 Genes up-regulated in more than one of several human hepatoma cell lines by TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.516E-4 3.097E-2
2.370E-1
4.167E-1
 2 50
14 16356477-Table1 Human Breast Song06 62genes GeneSigDB 3.658E-4 3.097E-2
2.370E-1
4.335E-1
 2 51
15 M10332 Genes up-regulated in hyppocampus at late postnatal stages (clusters 11 and 15). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.583E-4 4.410E-2
3.376E-1
6.615E-1
 2 63
16 M4001 Genes down-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.501E-4 4.815E-2
3.686E-1
7.704E-1
 2 68
Show 11 more annotations

14: Coexpression Atlas [Display Chart] 13 input genes in category / 920 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal RCC PT-U/Kidney Normal RCC PT16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal RCC PT-U/Kidney Normal RCC PT16 Adult, Development, and Cancer types 4.649E-8 4.277E-5 3.166E-4 4.277E-5 5 182
2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal RCC F-U/Kidney Normal RCC F16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal RCC F-U/Kidney Normal RCC F16 Adult, Development, and Cancer types 5.779E-7 2.658E-4 1.968E-3 5.317E-4 4 119
3 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Medulla Wilms U U/Kidney Normal-Medulla Wilms U16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Medulla Wilms U U/Kidney Normal-Medulla Wilms U16 Adult, Development, and Cancer types 3.084E-6 5.383E-4 3.984E-3 2.837E-3 4 181
4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Cortex Wilms U U/Kidney Normal-Cortex Wilms U16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Cortex Wilms U U/Kidney Normal-Cortex Wilms U16 Adult, Development, and Cancer types 3.152E-6 5.383E-4 3.984E-3 2.900E-3 4 182
5 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal RCC EN-B/Kidney Normal RCC EN16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal RCC EN-B/Kidney Normal RCC EN16 Adult, Development, and Cancer types 3.292E-6 5.383E-4 3.984E-3 3.029E-3 4 184
6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Cortex Wilms Mast cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Cortex Wilms Mast cell Adult, Development, and Cancer types 3.510E-6 5.383E-4 3.984E-3 3.230E-3 4 187
7 gudmap kidney single cell adult RenalCortexMixed Scamp k4 500 kidney single cell adult RenalCortexMixed StemCellamp k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 6.504E-5 8.549E-3
6.328E-2
5.984E-2
 4 393
8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Medulla post-natal kidney NK cell/Kidney Normal-Medulla post-natal kidney NK16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Medulla post-natal kidney NK cell/Kidney Normal-Medulla post-natal kidney NK16 Adult, Development, and Cancer types 1.484E-4 8.561E-3
6.337E-2
1.365E-1
 3 180
9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex Wilms NK cell/Kidney Normal-Cortex Wilms NK16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex Wilms NK cell/Kidney Normal-Cortex Wilms NK16 Adult, Development, and Cancer types 1.484E-4 8.561E-3
6.337E-2
1.365E-1
 3 180
10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Medulla post-natal kidney Mast cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Medulla post-natal kidney Mast cell Adult, Development, and Cancer types 1.508E-4 8.561E-3
6.337E-2
1.388E-1
 3 181
11 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex post-natal kidney NK cell/Kidney Normal-Cortex post-natal kidney NK16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex post-natal kidney NK cell/Kidney Normal-Cortex post-natal kidney NK16 Adult, Development, and Cancer types 1.508E-4 8.561E-3
6.337E-2
1.388E-1
 3 181
12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Proliferating NK cell/Kidney Normal-Cortex post-natal kidney Proliferating NK cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Proliferating NK cell/Kidney Normal-Cortex post-natal kidney Proliferating NK cell Adult, Development, and Cancer types 1.533E-4 8.561E-3
6.337E-2
1.411E-1
 3 182
13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal-Cortex post-natal kidney R U/Kidney Normal-Cortex post-natal kidney R16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal-Cortex post-natal kidney R U/Kidney Normal-Cortex post-natal kidney R16 Adult, Development, and Cancer types 1.533E-4 8.561E-3
6.337E-2
1.411E-1
 3 182
14 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal-Medulla Wilms PT-U/Kidney Normal-Medulla Wilms PT16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal-Medulla Wilms PT-U/Kidney Normal-Medulla Wilms PT16 Adult, Development, and Cancer types 1.533E-4 8.561E-3
6.337E-2
1.411E-1
 3 182
15 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Normal-Medulla post-natal kidney IF-U/Kidney Normal-Medulla post-natal kidney IF16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Normal-Medulla post-natal kidney IF-U/Kidney Normal-Medulla post-natal kidney IF16 Adult, Development, and Cancer types 1.558E-4 8.561E-3
6.337E-2
1.434E-1
 3 183
16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal-Cortex post-natal kidney EN-B/Kidney Normal-Cortex post-natal kidney EN16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal-Cortex post-natal kidney EN-B/Kidney Normal-Cortex post-natal kidney EN16 Adult, Development, and Cancer types 1.583E-4 8.561E-3
6.337E-2
1.457E-1
 3 184
17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N16 Adult, Development, and Cancer types 1.687E-4 8.561E-3
6.337E-2
1.552E-1
 3 188
18 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N17 Adult, Development, and Cancer types 1.741E-4 8.561E-3
6.337E-2
1.602E-1
 3 190
19 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Plasmacytoid DC/Kidney Normal-Cortex Wilms Plasmacytoid DC Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Plasmacytoid DC/Kidney Normal-Cortex Wilms Plasmacytoid DC Adult, Development, and Cancer types 1.768E-4 8.561E-3
6.337E-2
1.627E-1
 3 191
20 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Normal RCC EN-A/Kidney Normal RCC EN8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Normal RCC EN-A/Kidney Normal RCC EN8 Adult, Development, and Cancer types 5.955E-4 2.739E-2
2.028E-1
5.479E-1
 1 1
21 Facebase RNAseq e10.5 Neural Epithelium Overlying Medial Eminence 500 K1 FacebaseRNAseq e10.5 Neural Epithelium Overlying Medial Eminence top-relative-expression-ranked 500 k-means-cluster#1 FaceBase_RNAseq 1.008E-3 4.415E-2
3.268E-1
9.272E-1
 2 80
Show 16 more annotations

15: Computational [Display Chart] 11 input genes in category / 82 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5757 MODULE 402 Genes in the cancer module 402. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.164E-5 5.875E-3 2.932E-2 5.875E-3 2 12
2 M1212 MODULE 492 Genes in the cancer module 492. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.472E-4 6.035E-3 3.011E-2 1.207E-2 2 17
3 M13513 MODULE 307 Oxidative phosphorylation (COX and ATPases). MSigDb: C4 - CM: Cancer Modules (v6.0) 3.231E-4 8.832E-3 4.407E-2 2.650E-2 2 25
4 M9417 MODULE 116 Genes in the cancer module 116. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.363E-4 8.943E-3 4.463E-2 3.577E-2 2 29
5 M3482 MODULE 36 Genes in the cancer module 36. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.192E-4 1.015E-2
5.067E-2
5.077E-2
 3 162
6 M1566 MODULE 568 Genes in the cancer module 568. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.751E-3 3.699E-2
1.846E-1
2.255E-1
 2 73
7 M15916 MODULE 491 Genes in the cancer module 491. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.213E-3 3.699E-2
1.846E-1
2.635E-1
 2 79
8 M10404 MORF MBD4 Neighborhood of MBD4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.796E-3 3.699E-2
1.846E-1
3.113E-1
 2 86
9 M16474 MODULE 62 Genes in the cancer module 62. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.060E-3 3.699E-2
1.846E-1
3.329E-1
 2 89
Show 4 more annotations

16: MicroRNA [Display Chart] 13 input genes in category / 442 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-3666:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.495E-5 3.356E-3 2.238E-2 1.545E-2 3 364
2 hsa-miR-4295:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.552E-5 3.356E-3 2.238E-2 1.570E-2 3 366
3 hsa-miR-301b-3p:Non-Functional MTI Non-Functional MTI miRTarbase 3.818E-5 3.356E-3 2.238E-2 1.688E-2 3 375
4 hsa-miR-301a-3p:Functional MTI Functional MTI miRTarbase 4.455E-5 3.356E-3 2.238E-2 1.969E-2 3 395
5 hsa-miR-454-3p:Functional MTI Functional MTI miRTarbase 4.488E-5 3.356E-3 2.238E-2 1.984E-2 3 396
6 hsa-miR-130a-3p:Functional MTI Functional MTI miRTarbase 4.556E-5 3.356E-3 2.238E-2 2.014E-2 3 398
7 hsa-miR-886-3p:mirSVR lowEffct hsa-miR-886-3p:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 7.597E-5 4.797E-3 3.199E-2 3.358E-2 3 473
8 hsa-miR-99a-5p:Functional MTI Functional MTI miRTarbase 2.589E-4 1.431E-2
9.542E-2
1.144E-1
 2 133
9 hsa-miR-490-3p:TargetScan hsa-miR-490-3p TargetScan 3.978E-4 1.954E-2
1.303E-1
1.758E-1
 2 165
10 hsa-miR-1238:mirSVR highEffct hsa-miR-1238:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.606E-4 2.288E-2
1.526E-1
2.920E-1
 2 213
11 hsa-miR-649:PITA hsa-miR-649:PITA TOP PITA 6.606E-4 2.288E-2
1.526E-1
2.920E-1
 2 213
12 hsa-miR-329:PITA hsa-miR-329:PITA TOP PITA 6.730E-4 2.288E-2
1.526E-1
2.975E-1
 2 215
13 hsa-miR-362-3p:PITA hsa-miR-362-3p:PITA TOP PITA 6.730E-4 2.288E-2
1.526E-1
2.975E-1
 2 215
14 ATGTTAA,MIR-302C:MSigDB ATGTTAA,MIR-302C:MSigDB MSigDB 7.825E-4 2.471E-2
1.648E-1
3.459E-1
 2 232
15 hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA TOP PITA 1.250E-3 3.091E-2
2.061E-1
5.525E-1
 2 294
16 hsa-miR-196a-5p:Functional MTI Functional MTI miRTarbase 1.327E-3 3.091E-2
2.061E-1
5.863E-1
 2 303
17 hsa-miR-513b:PITA hsa-miR-513b:PITA TOP PITA 1.505E-3 3.091E-2
2.061E-1
6.651E-1
 2 323
18 hsa-miR-10a*:mirSVR highEffct hsa-miR-10a*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.588E-3 3.091E-2
2.061E-1
7.021E-1
 2 332
19 hsa-miR-4321:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.619E-3 3.091E-2
2.061E-1
7.154E-1
 1 9
20 hsa-miR-423-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.694E-3 3.091E-2
2.061E-1
7.486E-1
 2 343
21 hsa-miR-519b-3p:Functional MTI Functional MTI miRTarbase 1.703E-3 3.091E-2
2.061E-1
7.529E-1
 2 344
22 hsa-miR-519a-3p:Functional MTI Functional MTI miRTarbase 1.752E-3 3.091E-2
2.061E-1
7.746E-1
 2 349
23 hsa-miR-519c-3p:Functional MTI Functional MTI miRTarbase 1.762E-3 3.091E-2
2.061E-1
7.790E-1
 2 350
24 hsa-miR-572:mirSVR lowEffct hsa-miR-572:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 1.792E-3 3.091E-2
2.061E-1
7.921E-1
 2 353
25 hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 2.325E-3 3.091E-2
2.061E-1
1.000E0
 2 403
26 hsa-miR-6082:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.337E-3 3.091E-2
2.061E-1
1.000E0
 1 13
27 hsa-miR-888:PITA hsa-miR-888:PITA TOP PITA 2.521E-3 3.091E-2
2.061E-1
1.000E0
 2 420
28 hsa-miR-1250-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.696E-3 3.091E-2
2.061E-1
1.000E0
 1 15
29 hsa-miR-611:mirSVR lowEffct hsa-miR-611:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.725E-3 3.091E-2
2.061E-1
1.000E0
 2 437
30 hsa-miR-448:PITA hsa-miR-448:PITA TOP PITA 2.737E-3 3.091E-2
2.061E-1
1.000E0
 2 438
31 hsa-miR-302e:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.861E-3 3.091E-2
2.061E-1
1.000E0
 2 448
32 hsa-miR-520d-3p:Functional MTI Functional MTI miRTarbase 2.873E-3 3.091E-2
2.061E-1
1.000E0
 2 449
33 hsa-miR-555:mirSVR highEffct hsa-miR-555:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.898E-3 3.091E-2
2.061E-1
1.000E0
 2 451
34 hsa-miR-802:PITA hsa-miR-802:PITA TOP PITA 2.911E-3 3.091E-2
2.061E-1
1.000E0
 2 452
35 hsa-miR-520e:Functional MTI Functional MTI miRTarbase 2.923E-3 3.091E-2
2.061E-1
1.000E0
 2 453
36 hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 2.949E-3 3.091E-2
2.061E-1
1.000E0
 2 455
37 hsa-miR-520c-3p:Functional MTI Functional MTI miRTarbase 2.949E-3 3.091E-2
2.061E-1
1.000E0
 2 455
38 hsa-miR-520b:Functional MTI Functional MTI miRTarbase 2.949E-3 3.091E-2
2.061E-1
1.000E0
 2 455
39 hsa-miR-26a-5p:Functional MTI Functional MTI miRTarbase 2.974E-3 3.091E-2
2.061E-1
1.000E0
 2 457
40 hsa-miR-103-as:mirSVR highEffct hsa-miR-103-as:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.987E-3 3.091E-2
2.061E-1
1.000E0
 2 458
41 hsa-miR-302b-3p:Functional MTI Functional MTI miRTarbase 3.012E-3 3.091E-2
2.061E-1
1.000E0
 2 460
42 hsa-miR-302d-3p:Functional MTI Functional MTI miRTarbase 3.012E-3 3.091E-2
2.061E-1
1.000E0
 2 460
43 hsa-miR-372-3p:Non-Functional MTI Non-Functional MTI miRTarbase 3.025E-3 3.091E-2
2.061E-1
1.000E0
 2 461
44 hsa-miR-302a-3p:Functional MTI Functional MTI miRTarbase 3.077E-3 3.091E-2
2.061E-1
1.000E0
 2 465
45 hsa-miR-148a:PITA hsa-miR-148a:PITA TOP PITA 3.314E-3 3.164E-2
2.110E-1
1.000E0
 2 483
46 hsa-miR-302c-3p.2:TargetScan hsa-miR-302c-3p.2 TargetScan 3.435E-3 3.164E-2
2.110E-1
1.000E0
 2 492
47 hsa-miR-3131:mirSVR lowEffct hsa-miR-3131:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 3.435E-3 3.164E-2
2.110E-1
1.000E0
 2 492
48 hsa-miR-520f-3p:TargetScan hsa-miR-520f-3p TargetScan 3.435E-3 3.164E-2
2.110E-1
1.000E0
 2 492
49 hsa-miR-4523:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.593E-3 3.241E-2
2.162E-1
1.000E0
 1 20
50 hsa-miR-1250:PITA hsa-miR-1250:PITA TOP PITA 5.207E-3 4.603E-2
3.070E-1
1.000E0
 1 29
Show 45 more annotations

17: Drug [Display Chart] 13 input genes in category / 3716 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000002287 NSC381866 Stitch 9.946E-15 3.696E-11 3.252E-10 3.696E-11 8 170
2 CID000004591 AC1L1IIA Stitch 2.006E-12 3.728E-9 3.279E-8 7.455E-9 7 172
3 CID000010868 DCCD Stitch 1.248E-10 1.545E-7 1.360E-6 4.636E-7 6 151
4 CID000061672 orthovanadate Stitch 1.346E-9 1.251E-6 1.100E-5 5.003E-6 7 435
5 CID000384608 AC1L8NTU Stitch 2.817E-9 2.093E-6 1.842E-5 1.047E-5 5 109
6 CID000023990 vanadium Stitch 1.363E-8 8.439E-6 7.425E-5 5.064E-5 5 149
7 CID000415541 IN1025 Stitch 1.130E-7 6.000E-5 5.279E-4 4.200E-4 4 83
8 CID000024411 oxovanadium Stitch 4.994E-7 2.320E-4 2.041E-3 1.856E-3 4 120
9 CID000033558 azide Stitch 2.523E-6 1.042E-3 9.165E-3 9.376E-3 4 180
10 ctd:C081294 satraplatin CTD 2.987E-6 1.110E-3 9.767E-3 1.110E-2 2 5
11 CID000124822 copper histidinate Stitch 4.597E-6 1.553E-3 1.366E-2 1.708E-2 3 59
12 CID000000832 L-beta-aspartyl phosphate Stitch 7.384E-6 2.287E-3 2.012E-2 2.744E-2 3 69
13 CID011953896 2,3-Isoprolylideneerthrofuranosyl 2,3-O-isopropylideneerythrofuranoside Stitch 1.074E-5 3.070E-3 2.701E-2 3.991E-2 2 9
14 CID000444279 1sqc Stitch 1.342E-5 3.563E-3 3.134E-2 4.988E-2 2 10
15 CID000008718 2,5-dimethylquinone Stitch 1.640E-5 4.063E-3 3.574E-2
6.094E-2
 2 11
16 CID000013245 AC1MMLID Stitch 1.756E-5 4.079E-3 3.589E-2
6.527E-2
 3 92
17 CID004369390 1vyq Stitch 1.967E-5 4.300E-3 3.783E-2
7.310E-2
 2 12
18 CID000000186 acetyl phosphate Stitch 2.123E-5 4.383E-3 3.856E-2
7.890E-2
 3 98
19 CID000151012 p-hydroxyhippuric acid Stitch 2.711E-5 5.302E-3 4.664E-2
1.007E-1
 2 14
20 ctd:D016190 Carboplatin CTD 3.252E-5 6.016E-3
5.293E-2
1.209E-1
 3 113
21 CID016040251 PE-W Stitch 3.572E-5 6.016E-3
5.293E-2
1.327E-1
 2 16
22 CID000014974 Ostreogrycin B Stitch 3.572E-5 6.016E-3
5.293E-2
1.327E-1
 2 16
23 CID000374551 AC1L88YH Stitch 4.047E-5 6.016E-3
5.293E-2
1.504E-1
 2 17
24 CID011979418 RP 59500 Stitch 4.047E-5 6.016E-3
5.293E-2
1.504E-1
 2 17
25 CID011979535 Mikamycine Stitch 4.047E-5 6.016E-3
5.293E-2
1.504E-1
 2 17
26 CID000002603 carbonyl cyanide m-chlorophenylhydrazone Stitch 4.396E-5 6.264E-3
5.511E-2
1.634E-1
 3 125
27 CID000010104 NSC 234205 Stitch 4.552E-5 6.264E-3
5.511E-2
1.691E-1
 2 18
28 CID000091599 aluminum citrate Stitch 5.649E-5 7.238E-3
6.368E-2
2.099E-1
 2 20
29 ctd:D010984 Platinum CTD 5.649E-5 7.238E-3
6.368E-2
2.099E-1
 2 20
30 CID000015465 AC1L25Y6 Stitch 7.515E-5 9.008E-3
7.925E-2
2.792E-1
 2 23
31 CID000165791 lanthanum chloride hydrate Stitch 7.515E-5 9.008E-3
7.925E-2
2.792E-1
 2 23
32 CID000024854 CaCl2 Stitch 8.500E-5 9.870E-3
8.684E-2
3.159E-1
 3 156
33 CID005364545 cyhexatin Stitch 8.905E-5 1.003E-2
8.822E-2
3.309E-1
 2 25
34 CID000020667 dodecyl ether Stitch 9.644E-5 1.054E-2
9.273E-2
3.584E-1
 2 26
35 CID000454923 XK234 Stitch 1.040E-4 1.075E-2
9.455E-2
3.866E-1
 3 167
36 CID006914595 Bi-E Stitch 1.041E-4 1.075E-2
9.455E-2
3.869E-1
 2 27
37 ctd:D003958 Diamide CTD 1.121E-4 1.126E-2
9.904E-2
4.165E-1
 2 28
38 CID000078798 octaethylene glycol Stitch 1.204E-4 1.177E-2
1.035E-1
4.472E-1
 2 29
39 CID006434704 Ormaplatino Stitch 1.378E-4 1.258E-2
1.107E-1
5.119E-1
 2 31
40 CID006436102 NF T Stitch 1.524E-4 1.258E-2
1.107E-1
5.663E-1
 3 190
41 7053 DN thapsigargin; Down 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.524E-4 1.258E-2
1.107E-1
5.663E-1
 3 190
42 CID000104406 E1-P Stitch 1.563E-4 1.258E-2
1.107E-1
5.809E-1
 2 33
43 3861 DN Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.621E-4 1.258E-2
1.107E-1
6.022E-1
 3 194
44 3526 UP Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.621E-4 1.258E-2
1.107E-1
6.022E-1
 3 194
45 5241 UP haloperidol; Up 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.645E-4 1.258E-2
1.107E-1
6.114E-1
 3 195
46 1445 UP Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Up 1.670E-4 1.258E-2
1.107E-1
6.207E-1
 3 196
47 4974 UP Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.670E-4 1.258E-2
1.107E-1
6.207E-1
 3 196
48 4125 DN Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.670E-4 1.258E-2
1.107E-1
6.207E-1
 3 196
49 7450 DN Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.721E-4 1.258E-2
1.107E-1
6.396E-1
 3 198
50 3249 UP Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.747E-4 1.258E-2
1.107E-1
6.491E-1
 3 199
Show 45 more annotations

18: Disease [Display Chart] 13 input genes in category / 449 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0012714 Disorder of copper metabolism DisGeNET BeFree 1.613E-9 7.240E-7 4.840E-6 7.240E-7 3 4
2 C0268070 Hypocupremia DisGeNET Curated 2.725E-7 6.117E-5 4.090E-4 1.223E-4 3 17
3 C0022716 Menkes Kinky Hair Syndrome DisGeNET Curated 2.219E-4 1.162E-2
7.768E-2
9.965E-2
 2 28
4 C1836330 ERYTHROKERATODERMIA VARIABILIS 3 (disorder) DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
5 cv:C1832918 Brody myopathy Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
6 C4024907 Mixed demyelinating and axonal polyneuropathy DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
7 cv:C1836330 Erythrokeratodermia variabilis 3 Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
8 cv:CN181443 Parkinsonism with spasticity, X-linked Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
9 C4025211 Abnormality of the carotid arteries DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
10 C4280490 Low hanging nasal septum DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
11 cv:C0019202 Wilson's disease Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
12 OMIN:277900 WILSON DISEASE OMIM 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
13 C1848456 Atypical or prolonged hepatitis DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
14 cv:C1864498 Renal tubular acidosis, distal, autosomal recessive Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
15 OMIN:300489 SPINAL MUSCULAR ATROPHY, DISTAL, X-LINKED 3; SMAX3 OMIM 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
16 C1845543 Mental Retardation, X-Linked, with Epilepsy DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
17 OMIN:304150 OCCIPITAL HORN SYNDROME; OHS OMIM 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
18 cv:C1845543 Mental retardation, X-linked, syndromic, Hedera type Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
19 cv:C0022716 Menkes kinky-hair syndrome Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
20 OMIN:601003 BRODY MYOPATHY OMIM 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
21 cv:C1845359 Distal spinal muscular atrophy, X-linked 3 Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
22 cv:C0268353 Cutis laxa, X-linked Clinical Variations 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
23 C4025216 Prominent nasal septum DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
24 C1303076 Tortuous carotid artery DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
25 C4225321 ZIMMERMANN-LABAND SYNDROME 2 DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
26 C1845359 Spinal Muscular Atrophy, Distal, X-Linked 3 DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
27 C1876166 Endemic Tyrolean Infantile Cirrhosis DisGeNET BeFree 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
28 C2675730 Deafness, Congenital, and Onychodystrophy, Autosomal Dominant DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
29 C4280489 Visible nasal septum DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
30 C1848459 High nonceruloplasmin-bound serum copper DisGeNET Curated 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
31 OMIN:309400 MENKES DISEASE OMIM 8.022E-4 1.162E-2
7.768E-2
3.602E-1
 1 1
32 C0026946 Mycoses DisGeNET BeFree 9.147E-4 1.258E-2
8.413E-2
4.107E-1
 3 249
33 C1384514 Conn Syndrome DisGeNET BeFree 9.249E-4 1.258E-2
8.413E-2
4.153E-1
 2 57
34 C0019202 Hepatolenticular Degeneration DisGeNET Curated 1.238E-3 1.532E-2
1.024E-1
5.558E-1
 2 66
35 C0031117 Peripheral Neuropathy DisGeNET Curated 1.244E-3 1.532E-2
1.024E-1
5.588E-1
 3 277
36 C0423798 Increased tendency to bruise DisGeNET Curated 1.275E-3 1.532E-2
1.024E-1
5.727E-1
 2 67
37 C0013491 Ecchymosis DisGeNET Curated 1.275E-3 1.532E-2
1.024E-1
5.727E-1
 2 67
38 C0151564 Cogwheel Rigidity DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
39 C0679145 sexual addiction DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
40 C4025831 Abnormal peripheral nervous system morphology DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
41 C1848453 Poor motor coordination DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
42 C0152457 Kayser-Fleischer ring DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
43 OMIN:602722 RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE; RTADR OMIM 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
44 OMIN:609015 TRIFUNCTIONAL PROTEIN DEFICIENCY OMIM 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
45 C1832988 Metaphyseal spurs DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
46 cv:C0342786 Mitochondrial trifunctional protein deficiency Clinical Variations 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
47 C3806722 PARKINSONISM WITH SPASTICITY, X-LINKED DisGeNET Curated 1.604E-3 1.532E-2
1.024E-1
7.201E-1
 1 2
48 C0438237 Liver enzymes abnormal DisGeNET Curated 1.857E-3 1.544E-2
1.032E-1
8.339E-1
 2 81
49 C0151766 Liver function tests abnormal finding DisGeNET Curated 1.857E-3 1.544E-2
1.032E-1
8.339E-1
 2 81
50 C1842003 Subclinical abnormal liver function tests DisGeNET Curated 1.857E-3 1.544E-2
1.032E-1
8.339E-1
 2 81
Show 45 more annotations