|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
18714142
|
Human and mouse enamel phenotypes resulting from mutation or altered expression of AMEL, ENAM, MMP20 and KLK4.
|
Pubmed
|
3.769E-11
|
1.148E-8
|
8.492E-8
|
3.445E-8
|
3
|
5
|
|
2
|
23790503
|
Genes expressed in dental enamel development are associated with molar-incisor hypomineralization.
|
Pubmed
|
3.769E-11
|
1.148E-8
|
8.492E-8
|
3.445E-8
|
3
|
5
|
|
3
|
18781068
|
Enamel formation genes are associated with high caries experience in Turkish children.
|
Pubmed
|
3.769E-11
|
1.148E-8
|
8.492E-8
|
3.445E-8
|
3
|
5
|
|
4
|
19251658
|
Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis.
|
Pubmed
|
1.319E-10
|
3.014E-8
|
2.229E-7
|
1.206E-7
|
3
|
7
|
|
5
|
21285247
|
PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.
|
Pubmed
|
1.371E-9
|
2.506E-7
|
1.853E-6
|
1.253E-6
|
3
|
14
|
|
6
|
27896288
|
Ultrastructure of early amelogenesis in wild-type,
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
7
|
11877393
|
Altered amelogenin self-assembly based on mutations observed in human X-linked amelogenesis imperfecta (AIH1).
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
8
|
7782077
|
Amelogenin signal peptide mutation: correlation between mutations in the amelogenin gene (AMGX) and manifestations of X-linked amelogenesis imperfecta.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
9
|
25791822
|
Enamel formation genes associated with dental erosive wear.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
10
|
23948316
|
Characterization of copy number variation in genomic regions containing STR loci using array comparative genomic hybridization.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
11
|
22759786
|
Phenotype-genotype correlations in mouse models of amelogenesis imperfecta caused by Amelx and Enam mutations.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
12
|
9199671
|
Immunohistochemical similarities and differences between amelogenin and tuftelin gene products during tooth development.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
13
|
2004775
|
A human X-Y homologous region encodes "amelogenin".
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
14
|
9041053
|
Protein interactions during assembly of the enamel organic extracellular matrix.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
15
|
2737677
|
Human and mouse amelogenin gene loci are on the sex chromosomes.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
16
|
18067069
|
[Types and frequencies of variants in Amelogenin gene in Chinese population].
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
17
|
11406633
|
Amelogenin-deficient mice display an amelogenesis imperfecta phenotype.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
18
|
22813216
|
Does enamelin have pleiotropic effects on organs other than the teeth? Lessons from a phenotyping screen of two enamelin-mutant mouse lines.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
19
|
11852235
|
Analysis of self-assembly and apatite binding properties of amelogenin proteins lacking the hydrophilic C-terminal.
|
Pubmed
|
2.879E-8
|
1.385E-6
|
1.024E-5
|
2.632E-5
|
2
|
2
|
|
20
|
1734713
|
The human enamel protein gene amelogenin is expressed from both the X and the Y chromosomes.
|
Pubmed
|
8.637E-8
|
3.588E-6
|
2.654E-5
|
7.894E-5
|
2
|
3
|
|
21
|
24167599
|
Identification of novel amelogenin-binding proteins by proteomics analysis.
|
Pubmed
|
8.637E-8
|
3.588E-6
|
2.654E-5
|
7.894E-5
|
2
|
3
|
|
22
|
16674683
|
Amelogenin, a major structural protein in mineralizing enamel, is also expressed in soft tissues: brain and cells of the hematopoietic system.
|
Pubmed
|
8.637E-8
|
3.588E-6
|
2.654E-5
|
7.894E-5
|
2
|
3
|
|
23
|
25122764
|
A pituitary homeobox 2 (Pitx2):microRNA-200a-3p:β-catenin pathway converts mesenchymal cells to amelogenin-expressing dental epithelial cells.
|
Pubmed
|
1.727E-7
|
6.864E-6
|
5.076E-5
|
1.579E-4
|
2
|
4
|
|
24
|
9074935
|
Timing of the expression of enamel gene products during mouse tooth development.
|
Pubmed
|
2.879E-7
|
9.745E-6
|
7.207E-5
|
2.631E-4
|
2
|
5
|
|
25
|
23975681
|
A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome.
|
Pubmed
|
2.879E-7
|
9.745E-6
|
7.207E-5
|
2.631E-4
|
2
|
5
|
|
26
|
11063034
|
Induction of amelogenin and ameloblastin by insulin and insulin-like growth factors (IGF-I and IGF-II) during embryonic mouse tooth development in vitro.
|
Pubmed
|
2.879E-7
|
9.745E-6
|
7.207E-5
|
2.631E-4
|
2
|
5
|
|
27
|
9927592
|
Extracellular proteolysis alters tooth development in transgenic mice expressing urokinase-type plasminogen activator in the enamel organ.
|
Pubmed
|
2.879E-7
|
9.745E-6
|
7.207E-5
|
2.631E-4
|
2
|
5
|
|
28
|
16314533
|
periostin null mice exhibit dwarfism, incisor enamel defects, and an early-onset periodontal disease-like phenotype.
|
Pubmed
|
4.318E-7
|
1.409E-5
|
1.042E-4
|
3.946E-4
|
2
|
6
|
|
29
|
25789606
|
A secretory kinase complex regulates extracellular protein phosphorylation.
|
Pubmed
|
6.044E-7
|
1.905E-5
|
1.409E-4
|
5.524E-4
|
2
|
7
|
|
30
|
18703497
|
The cell adhesion molecule nectin-1 is critical for normal enamel formation in mice.
|
Pubmed
|
8.058E-7
|
2.455E-5
|
1.816E-4
|
7.365E-4
|
2
|
8
|
|
31
|
22866057
|
Gene Expression Profiling during Murine Tooth Development.
|
Pubmed
|
2.244E-6
|
6.214E-5
|
4.596E-4
|
2.051E-3
|
2
|
13
|
|
32
|
10675334
|
Transcription factor Sp3 is essential for post-natal survival and late tooth development.
|
Pubmed
|
2.244E-6
|
6.214E-5
|
4.596E-4
|
2.051E-3
|
2
|
13
|
|
33
|
28174279
|
A cytoplasmic role of Wnt/β-catenin transcriptional cofactors Bcl9, Bcl9l, and Pygopus in tooth enamel formation.
|
Pubmed
|
2.244E-6
|
6.214E-5
|
4.596E-4
|
2.051E-3
|
2
|
13
|
|
34
|
22629441
|
BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor.
|
Pubmed
|
4.399E-6
|
1.183E-4
|
8.746E-4
|
4.021E-3
|
2
|
18
|
|
35
|
20487000
|
Gene expression and dental enamel structure in developing mouse incisor.
|
Pubmed
|
6.640E-6
|
1.734E-4
|
1.282E-3
|
6.069E-3
|
2
|
22
|
|
36
|
19320717
|
Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse.
|
Pubmed
|
1.166E-5
|
2.961E-4
|
2.190E-3
|
1.066E-2
|
2
|
29
|
|
37
|
27330109
|
Transcription factor Bcl11b sustains iNKT1 and iNKT2 cell programs, restricts iNKT17 cell program, and governs iNKT cell survival.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
38
|
22653892
|
The circadian clock modulates enamel development.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
39
|
21514271
|
Human amelogenin up-regulates osteogenic gene expression in human bone marrow stroma cells.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
40
|
16293627
|
Reuptake of extracellular amelogenin by dental epithelial cells results in increased levels of amelogenin mRNA through enhanced mRNA stabilization.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
41
|
25816241
|
Cloning and characterization of the human integrin β6 gene promoter.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
42
|
1729173
|
Chromosomal locations of the genes coding for the integrin beta 6 and beta 7 subunits.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
43
|
26545753
|
Amelogenin in Enamel Tissue Engineering.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
44
|
26709694
|
Controlled Osteogenic Differentiation of Mouse Mesenchymal Stem Cells by Tetracycline-Controlled Transcriptional Activation of Amelogenin.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
45
|
7959743
|
Regional localization of the human integrin beta 6 gene (ITGB6) to chromosome 2q24-q31.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
46
|
21990045
|
Novel FAM20A mutations in hypoplastic amelogenesis imperfecta.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
47
|
20854469
|
Skin wound healing in diabetic β6 integrin-deficient mice.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
48
|
16284958
|
Thermal denaturation of a recombinant mouse amelogenin: circular dichroism and differential scanning calorimetric studies.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
49
|
19025992
|
Changes in the quaternary structure of amelogenin when adsorbed onto surfaces.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|
|
50
|
26096706
|
Depletion of B cell CLL/Lymphoma 11B Gene Expression Represses Glioma Cell Growth.
|
Pubmed
|
1.833E-4
|
6.048E-4
|
4.473E-3
|
1.675E-1
|
1
|
1
|