Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc297_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 46 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0022851 GABA-gated chloride ion channel activity 5.358E-4 1.848E-2
8.164E-2
 2.465E-2 1 2
2 GO:0005302 L-tyrosine transmembrane transporter activity 8.036E-4 1.848E-2
8.164E-2
 3.697E-2 1 3
3 GO:0015173 aromatic amino acid transmembrane transporter activity 1.339E-3 2.053E-2
9.069E-2
6.160E-2
 1 5
4 GO:0008509 anion transmembrane transporter activity 2.446E-3 2.463E-2
1.088E-1
1.125E-1
 2 297
5 GO:0035612 AP-2 adaptor complex binding 2.677E-3 2.463E-2
1.088E-1
1.231E-1
 1 10
6 GO:0004890 GABA-A receptor activity 5.081E-3 3.823E-2
1.689E-1
2.337E-1
 1 19
7 GO:0016917 GABA receptor activity 5.881E-3 3.823E-2
1.689E-1
2.705E-1
 1 22
8 GO:0022835 transmitter-gated channel activity 7.481E-3 3.823E-2
1.689E-1
3.441E-1
 1 28
9 GO:0022824 transmitter-gated ion channel activity 7.481E-3 3.823E-2
1.689E-1
3.441E-1
 1 28
Show 4 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 112 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0015828 tyrosine transport 2.685E-4 1.504E-2
7.969E-2
 3.007E-2 1 1
2 GO:0035037 sperm entry 2.685E-4 1.504E-2
7.969E-2
 3.007E-2 1 1
3 GO:0006726 eye pigment biosynthetic process 1.074E-3 2.147E-2
1.138E-1
1.202E-1
 1 4
4 GO:0043324 pigment metabolic process involved in developmental pigmentation 1.342E-3 2.147E-2
1.138E-1
1.503E-1
 1 5
5 GO:0042441 eye pigment metabolic process 1.342E-3 2.147E-2
1.138E-1
1.503E-1
 1 5
6 GO:0015801 aromatic amino acid transport 1.342E-3 2.147E-2
1.138E-1
1.503E-1
 1 5
7 GO:0043474 pigment metabolic process involved in pigmentation 1.342E-3 2.147E-2
1.138E-1
1.503E-1
 1 5
8 GO:0098656 anion transmembrane transport 1.976E-3 2.671E-2
1.416E-1
2.213E-1
 2 266
9 GO:0071420 cellular response to histamine 2.146E-3 2.671E-2
1.416E-1
2.404E-1
 1 8
10 GO:0034776 response to histamine 2.950E-3 3.277E-2
1.737E-1
3.304E-1
 1 11
11 GO:0048069 eye pigmentation 3.218E-3 3.277E-2
1.737E-1
3.604E-1
 1 12
12 GO:0060736 prostate gland growth 3.754E-3 3.503E-2
1.857E-1
4.204E-1
 1 14
13 GO:0042438 melanin biosynthetic process 4.824E-3 4.156E-2
2.203E-1
5.403E-1
 1 18
14 GO:0006582 melanin metabolic process 5.359E-3 4.201E-2
2.227E-1
6.002E-1
 1 20
15 GO:0060080 inhibitory postsynaptic potential 5.626E-3 4.201E-2
2.227E-1
6.301E-1
 1 21
16 GO:0044550 secondary metabolite biosynthetic process 6.695E-3 4.332E-2
2.296E-1
7.498E-1
 1 25
17 GO:0060384 innervation 6.695E-3 4.332E-2
2.296E-1
7.498E-1
 1 25
18 GO:0007214 gamma-aminobutyric acid signaling pathway 6.962E-3 4.332E-2
2.296E-1
7.797E-1
 1 26
19 GO:0030318 melanocyte differentiation 7.496E-3 4.419E-2
2.342E-1
8.395E-1
 1 28
Show 14 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 38 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0033162 melanosome membrane 2.359E-3 1.899E-2
8.029E-2
8.964E-2
 1 9
2 GO:0045009 chitosome 2.359E-3 1.899E-2
8.029E-2
8.964E-2
 1 9
3 GO:0005687 U4 snRNP 2.621E-3 1.899E-2
8.029E-2
9.959E-2
 1 10
4 GO:0005682 U5 snRNP 4.190E-3 1.899E-2
8.029E-2
1.592E-1
 1 16
5 GO:0071004 U2-type prespliceosome 4.190E-3 1.899E-2
8.029E-2
1.592E-1
 1 16
6 GO:0005685 U1 snRNP 4.452E-3 1.899E-2
8.029E-2
1.692E-1
 1 17
7 GO:1902710 GABA receptor complex 4.713E-3 1.899E-2
8.029E-2
1.791E-1
 1 18
8 GO:1902711 GABA-A receptor complex 4.713E-3 1.899E-2
8.029E-2
1.791E-1
 1 18
9 GO:0005686 U2 snRNP 4.975E-3 1.899E-2
8.029E-2
1.890E-1
 1 19
10 GO:0060077 inhibitory synapse 5.236E-3 1.899E-2
8.029E-2
1.990E-1
 1 20
11 GO:0071010 prespliceosome 5.497E-3 1.899E-2
8.029E-2
2.089E-1
 1 21
12 GO:0046540 U4/U6 x U5 tri-snRNP complex 6.019E-3 1.906E-2
8.059E-2
2.287E-1
 1 23
13 GO:0097526 spliceosomal tri-snRNP complex 7.324E-3 2.141E-2
9.051E-2
2.783E-1
 1 28
14 GO:0005684 U2-type spliceosomal complex 8.106E-3 2.200E-2
9.302E-2
3.080E-1
 1 31
15 GO:0034707 chloride channel complex 1.305E-2 3.306E-2
1.398E-1
4.958E-1
 1 50
16 GO:0097525 spliceosomal snRNP complex 1.409E-2 3.346E-2
1.414E-1
5.353E-1
 1 54
17 GO:0030532 small nuclear ribonucleoprotein complex 1.590E-2 3.554E-2
1.503E-1
6.042E-1
 1 61
18 GO:0000502 proteasome complex 2.030E-2 4.285E-2
1.812E-1
7.712E-1
 1 78
19 GO:0071013 catalytic step 2 spliceosome 2.339E-2 4.678E-2
1.978E-1
8.888E-1
 1 90
20 GO:0042470 melanosome 2.724E-2 4.930E-2
2.084E-1
1.000E0
 1 105
21 GO:0048770 pigment granule 2.724E-2 4.930E-2
2.084E-1
1.000E0
 1 105
Show 16 more annotations

4: Human Phenotype [Display Chart] 4 input genes in category / 391 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0000748 Inappropriate laughter 5.667E-5 1.202E-2
7.867E-2
 2.216E-2 2 15
2 HP:0011150 Myoclonic absence 9.219E-5 1.202E-2
7.867E-2
 3.605E-2 2 19
3 HP:0011148 Absence seizures with special features 9.219E-5 1.202E-2
7.867E-2
 3.605E-2 2 19
4 HP:0007270 Atypical absence seizure 1.244E-4 1.216E-2
7.964E-2
 4.865E-2 2 22
5 HP:0000635 Blue irides 2.183E-4 1.707E-2
1.117E-1
8.534E-2
 2 29
6 HP:0000729 Autistic behavior 5.897E-4 1.757E-2
1.150E-1
2.306E-1
 3 253
7 HP:0011097 Epileptic spasms 6.031E-4 1.757E-2
1.150E-1
2.358E-1
 2 48
8 HP:0000752 Hyperactivity 6.250E-4 1.757E-2
1.150E-1
2.444E-1
 3 258
9 HP:0010864 Intellectual disability, severe 6.250E-4 1.757E-2
1.150E-1
2.444E-1
 3 258
10 HP:0001107 Ocular albinism 7.153E-4 1.757E-2
1.150E-1
2.797E-1
 3 270
11 HP:0007513 Generalized hypopigmentation 7.153E-4 1.757E-2
1.150E-1
2.797E-1
 3 270
12 HP:0001022 Albinism 7.153E-4 1.757E-2
1.150E-1
2.797E-1
 3 270
13 HP:0001010 Hypopigmentation of the skin 7.153E-4 1.757E-2
1.150E-1
2.797E-1
 3 270
14 HP:0005599 Hypopigmentation of hair 7.153E-4 1.757E-2
1.150E-1
2.797E-1
 3 270
15 HP:0009887 Abnormality of hair pigmentation 7.311E-4 1.757E-2
1.150E-1
2.859E-1
 3 272
16 HP:0000735 Impaired social interactions 7.638E-4 1.757E-2
1.150E-1
2.987E-1
 2 54
17 HP:0002121 Absence seizure 7.638E-4 1.757E-2
1.150E-1
2.987E-1
 2 54
18 HP:0007730 Iris hypopigmentation 9.677E-4 2.072E-2
1.357E-1
3.784E-1
 3 299
19 HP:0012433 Abnormal social behavior 1.007E-3 2.072E-2
1.357E-1
3.938E-1
 2 62
20 HP:0000494 Downslanted palpebral fissures 1.087E-3 2.126E-2
1.392E-1
4.251E-1
 3 311
21 HP:0008034 Abnormal iris pigmentation 1.238E-3 2.244E-2
1.469E-1
4.842E-1
 3 325
22 HP:0002373 Febrile seizures 1.283E-3 2.244E-2
1.469E-1
5.017E-1
 2 70
23 HP:0011146 Dialeptic seizures 1.320E-3 2.244E-2
1.469E-1
5.161E-1
 2 71
24 HP:0000980 Pallor 2.088E-3 3.402E-2
2.227E-1
8.164E-1
 3 388
25 HP:0008762 Repetitive compulsive behavior 2.548E-3 3.943E-2
2.581E-1
9.962E-1
 1 3
26 HP:0000722 Obsessive-compulsive behavior 2.765E-3 3.943E-2
2.581E-1
1.000E0
 2 103
27 HP:0000733 Stereotypy 2.818E-3 3.943E-2
2.581E-1
1.000E0
 2 104
28 HP:0200006 Slanting of the palpebral fissure 2.961E-3 3.943E-2
2.581E-1
1.000E0
 3 437
29 HP:0002133 Status epilepticus 3.206E-3 3.943E-2
2.581E-1
1.000E0
 2 111
30 HP:0000719 Inappropriate behavior 3.263E-3 3.943E-2
2.581E-1
1.000E0
 2 112
31 HP:0007015 Poor gross motor coordination 3.396E-3 3.943E-2
2.581E-1
1.000E0
 1 4
32 HP:0011195 EEG with focal sharp slow waves 3.396E-3 3.943E-2
2.581E-1
1.000E0
 1 4
33 HP:0012000 EEG with generalized spikes 3.396E-3 3.943E-2
2.581E-1
1.000E0
 1 4
34 HP:0000256 Macrocephaly 3.507E-3 3.943E-2
2.581E-1
1.000E0
 3 463
35 HP:0040194 Increased head circumference 3.529E-3 3.943E-2
2.581E-1
1.000E0
 3 464
36 HP:0007359 Focal-onset seizure 3.740E-3 4.017E-2
2.630E-1
1.000E0
 2 120
37 HP:0000992 Cutaneous photosensitivity 3.802E-3 4.017E-2
2.630E-1
1.000E0
 2 121
38 HP:0007603 Freckles in sun-exposed areas 4.244E-3 4.148E-2
2.716E-1
1.000E0
 1 5
39 HP:0002236 Frontal upsweep of hair 4.244E-3 4.148E-2
2.716E-1
1.000E0
 1 5
40 HP:0000728 Impaired ability to form peer relationships 4.244E-3 4.148E-2
2.716E-1
1.000E0
 1 5
41 HP:0000721 Lack of spontaneous play 5.091E-3 4.368E-2
2.860E-1
1.000E0
 1 6
42 HP:0000732 Inflexible adherence to routines or rituals 5.091E-3 4.368E-2
2.860E-1
1.000E0
 1 6
43 HP:0000758 Impaired use of nonverbal behaviors 5.091E-3 4.368E-2
2.860E-1
1.000E0
 1 6
44 HP:0003144 Increased serum serotonin 5.091E-3 4.368E-2
2.860E-1
1.000E0
 1 6
45 HP:0000749 Paroxysmal bursts of laughter 5.091E-3 4.368E-2
2.860E-1
1.000E0
 1 6
46 HP:0007018 Attention deficit hyperactivity disorder 5.139E-3 4.368E-2
2.860E-1
1.000E0
 2 141
47 HP:0008947 Infantile muscular hypotonia 5.356E-3 4.368E-2
2.860E-1
1.000E0
 2 144
48 HP:0006887 Intellectual disability, progressive 5.727E-3 4.368E-2
2.860E-1
1.000E0
 2 149
49 HP:0007166 Paroxysmal dyskinesia 5.937E-3 4.368E-2
2.860E-1
1.000E0
 1 7
50 HP:0004283 Narrow palm 5.937E-3 4.368E-2
2.860E-1
1.000E0
 1 7
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 4 input genes in category / 322 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0001260 increased body weight 1.284E-6 2.067E-4 1.313E-3 4.133E-4 4 350
2 MP:0012323 increased total tissue mass 1.284E-6 2.067E-4 1.313E-3 4.133E-4 4 350
3 MP:0001264 increased body size 2.044E-6 2.194E-4 1.394E-3 6.583E-4 4 393
4 MP:0002068 abnormal parental behavior 1.875E-5 1.509E-3 9.588E-3 6.036E-3 3 175
5 MP:0004008 abnormal GABA-mediated receptor currents 3.348E-5 2.156E-3 1.370E-2 1.078E-2 2 25
6 MP:0001922 reduced male fertility 7.346E-5 3.548E-3 2.254E-2 2.365E-2 3 276
7 MP:0003216 absence seizures 8.687E-5 3.548E-3 2.254E-2 2.797E-2 2 40
8 MP:0003121 genetic imprinting 9.132E-5 3.548E-3 2.254E-2 2.940E-2 2 41
9 MP:0001447 abnormal nest building behavior 1.053E-4 3.548E-3 2.254E-2 3.391E-2 2 44
10 MP:0000948 nonconvulsive seizures 1.102E-4 3.548E-3 2.254E-2 3.548E-2 2 45
11 MP:0002557 abnormal social/conspecific interaction 1.791E-4 5.243E-3 3.331E-2
5.767E-2
 3 372
12 MP:0009991 abnormal cerebellum vermis lobule IV morphology 3.863E-4 9.588E-3
6.092E-2
1.244E-1
 1 1
13 MP:0001405 impaired coordination 3.871E-4 9.588E-3
6.092E-2
1.246E-1
 3 482
14 MP:0012167 abnormal epigenetic regulation of gene expression 4.237E-4 9.745E-3
6.192E-2
1.364E-1
 2 88
15 MP:0009994 abnormal cerebellum vermis lobule VI morphology 7.725E-4 1.309E-2
8.317E-2
2.487E-1
 1 2
16 MP:0009989 abnormal cerebellum vermis lobule II morphology 7.725E-4 1.309E-2
8.317E-2
2.487E-1
 1 2
17 MP:0009554 abnormal hair follicle melanin granule shape 7.725E-4 1.309E-2
8.317E-2
2.487E-1
 1 2
18 MP:0009993 abnormal cerebellum vermis lobule V morphology 7.725E-4 1.309E-2
8.317E-2
2.487E-1
 1 2
19 MP:0009990 abnormal cerebellum vermis lobule III morphology 7.725E-4 1.309E-2
8.317E-2
2.487E-1
 1 2
20 MP:0001386 abnormal maternal nurturing 8.674E-4 1.396E-2
8.872E-2
2.793E-1
 2 126
21 MP:0008779 abnormal maternal behavior 9.660E-4 1.481E-2
9.410E-2
3.110E-1
 2 133
22 MP:0020335 abnormal dentate gyrus neuron dendrite morphology 1.159E-3 1.622E-2
1.030E-1
3.730E-1
 1 3
23 MP:0009995 abnormal cerebellum vermis lobule VII morphology 1.159E-3 1.622E-2
1.030E-1
3.730E-1
 1 3
24 MP:0001931 abnormal oogenesis 1.343E-3 1.802E-2
1.145E-1
4.326E-1
 2 157
25 MP:0001469 abnormal contextual conditioning behavior 1.501E-3 1.913E-2
1.215E-1
4.832E-1
 2 166
26 MP:0008912 nervous 1.544E-3 1.913E-2
1.215E-1
4.973E-1
 1 4
27 MP:0006159 ocular albinism 1.930E-3 2.072E-2
1.316E-1
6.216E-1
 1 5
28 MP:0004490 type IV spiral ligament fibrocyte degeneration 1.930E-3 2.072E-2
1.316E-1
6.216E-1
 1 5
29 MP:0010389 mosaic coat color 1.930E-3 2.072E-2
1.316E-1
6.216E-1
 1 5
30 MP:0006409 vestibular ganglion hypoplasia 1.930E-3 2.072E-2
1.316E-1
6.216E-1
 1 5
31 MP:0009357 abnormal seizure response to inducing agent 2.065E-3 2.120E-2
1.347E-1
6.649E-1
 2 195
32 MP:0001468 abnormal temporal memory 2.107E-3 2.120E-2
1.347E-1
6.784E-1
 2 197
33 MP:0009233 enlarged sperm head 2.316E-3 2.193E-2
1.394E-1
7.458E-1
 1 6
34 MP:0009555 abnormal hair follicle melanin granule distribution 2.316E-3 2.193E-2
1.394E-1
7.458E-1
 1 6
35 MP:0001388 abnormal stationary movement 2.413E-3 2.220E-2
1.411E-1
7.771E-1
 2 211
36 MP:0004296 abnormal type IV spiral ligament fibrocytes 2.702E-3 2.342E-2
1.488E-1
8.699E-1
 1 7
37 MP:0001400 hyperresponsive 2.702E-3 2.342E-2
1.488E-1
8.699E-1
 1 7
38 MP:0008143 abnormal dendrite morphology 2.764E-3 2.342E-2
1.488E-1
8.901E-1
 2 226
39 MP:0009957 abnormal cerebellum vermis lobule morphology 3.087E-3 2.367E-2
1.504E-1
9.941E-1
 1 8
40 MP:0011627 decreased skin pigmentation 3.087E-3 2.367E-2
1.504E-1
9.941E-1
 1 8
41 MP:0002911 abnormal inhibitory postsynaptic potential 3.087E-3 2.367E-2
1.504E-1
9.941E-1
 1 8
42 MP:0004746 abnormal cochlear IHC afferent innervation pattern 3.087E-3 2.367E-2
1.504E-1
9.941E-1
 1 8
43 MP:0000869 abnormal cerebellum posterior vermis morphology 3.473E-3 2.530E-2
1.607E-1
1.000E0
 1 9
44 MP:0009962 abnormal cerebellum posterior lobe morphology 3.473E-3 2.530E-2
1.607E-1
1.000E0
 1 9
45 MP:0010193 abnormal choroid melanin granule morphology 3.858E-3 2.530E-2
1.607E-1
1.000E0
 1 10
46 MP:0011269 increased excitatory postsynaptic current amplitude 3.858E-3 2.530E-2
1.607E-1
1.000E0
 1 10
47 MP:0004632 abnormal cochlear OHC efferent innervation pattern 3.858E-3 2.530E-2
1.607E-1
1.000E0
 1 10
48 MP:0001513 limb grasping 3.869E-3 2.530E-2
1.607E-1
1.000E0
 2 268
49 MP:0001923 reduced female fertility 4.187E-3 2.530E-2
1.607E-1
1.000E0
 2 279
50 MP:0004962 decreased prostate gland weight 4.243E-3 2.530E-2
1.607E-1
1.000E0
 1 11
Show 45 more annotations

6: Domain [Display Chart] 5 input genes in category / 26 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR004680 Cit transptr-like dom InterPro 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
2 IPR009847 SNURF InterPro 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
3 PF07192 SNURF Pfam 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
4 IPR032353 AZUL InterPro 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
5 PF03600 CitMHS Pfam 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
6 PF16558 AZUL Pfam 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
7 IPR017134 UBE3A InterPro 2.669E-4 9.913E-4 3.821E-3 6.939E-3 1 1
8 IPR017131 snRNP-assoc SmB/SmN InterPro 5.337E-4 1.735E-3 6.686E-3 1.388E-2 1 2
9 IPR002289 GABAAb rcpt InterPro 8.005E-4 2.312E-3 8.913E-3 2.081E-2 1 3
10 PF01423 LSM Pfam 5.061E-3 1.038E-2 4.001E-2
1.316E-1
 1 19
11 IPR001163 LSM dom euk/arc InterPro 5.061E-3 1.038E-2 4.001E-2
1.316E-1
 1 19
12 SM00651 Sm SMART 5.061E-3 1.038E-2 4.001E-2
1.316E-1
 1 19
13 IPR010920 LSM dom InterPro 5.858E-3 1.038E-2 4.001E-2
1.523E-1
 1 22
14 IPR006028 GABAA/Glycine rcpt InterPro 6.124E-3 1.038E-2 4.001E-2
1.592E-1
 1 23
15 SM00119 HECTc SMART 7.186E-3 1.038E-2 4.001E-2
1.868E-1
 1 27
16 PS50237 HECT PROSITE 7.186E-3 1.038E-2 4.001E-2
1.868E-1
 1 27
17 IPR000569 HECT dom InterPro 7.186E-3 1.038E-2 4.001E-2
1.868E-1
 1 27
18 PF00632 HECT Pfam 7.186E-3 1.038E-2 4.001E-2
1.868E-1
 1 27
19 IPR018000 Neurotransmitter ion chnl CS InterPro 1.195E-2 1.248E-2 4.811E-2
3.108E-1
 1 45
20 PF02932 Neur chan memb Pfam 1.222E-2 1.248E-2 4.811E-2
3.177E-1
 1 46
21 IPR006029 Neurotrans-gated channel TM InterPro 1.248E-2 1.248E-2 4.811E-2
3.245E-1
 1 47
22 PF02931 Neur chan LBD Pfam 1.248E-2 1.248E-2 4.811E-2
3.245E-1
 1 47
23 IPR006201 Neur channel InterPro 1.248E-2 1.248E-2 4.811E-2
3.245E-1
 1 47
24 IPR006202 Neur chan lig-bd InterPro 1.248E-2 1.248E-2 4.811E-2
3.245E-1
 1 47
25 2.70.170.10 - Gene3D 1.248E-2 1.248E-2 4.811E-2
3.245E-1
 1 47
26 PS00236 NEUROTR ION CHANNEL PROSITE 1.248E-2 1.248E-2 4.811E-2
3.245E-1
 1 47
Show 21 more annotations

7: Pathway [Display Chart] 5 input genes in category / 26 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 138085 Coregulation of Androgen receptor activity BioSystems: Pathway Interaction Database 2.041E-4 5.308E-3 2.046E-2 5.308E-3 2 57
2 1270185 Melanin biosynthesis BioSystems: REACTOME 2.007E-3 2.609E-2
1.006E-1
5.218E-2
 1 5
3 1268814 GABA A receptor activation BioSystems: REACTOME 5.211E-3 4.516E-2
1.741E-1
1.355E-1
 1 13

8: Pubmed [Display Chart] 5 input genes in category / 957 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 9060416 A microsatellite map of the pink-eyed dilution (p) deletion complex in mouse chromosome 7. Pubmed 1.184E-14 1.133E-11 8.434E-11 1.133E-11 4 10
2 8601494 Molecular analysis of 36 mutations at the mouse pink-eyed dilution (p) locus. Pubmed 1.026E-13 4.911E-11 3.654E-10 9.822E-11 4 16
3 28009282 Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation. Pubmed 1.077E-12 3.436E-10 2.557E-9 1.031E-9 3 3
4 11074018 A novel ATPase on mouse chromosome 7 is a candidate gene for increased body fat. Pubmed 4.308E-12 1.031E-9 7.670E-9 4.123E-9 3 4
5 9195990 A candidate model for Angelman syndrome in the mouse. Pubmed 1.077E-11 2.061E-9 1.534E-8 1.031E-8 3 5
6 15620220 Physical mapping of the pink-eyed dilution complex in mouse chromosome 7 shows that Atp10c is the only transcript between Gabrb3 and Ube3a. Pubmed 2.154E-11 3.435E-9 2.556E-8 2.061E-8 3 6
7 1303276 Maternal imprinting of the mouse Snrpn gene and conserved linkage homology with the human Prader-Willi syndrome region. Pubmed 6.030E-11 8.244E-9 6.135E-8 5.771E-8 3 8
8 11668390 Microarray expression profiling of tissues from mice with uniparental duplications of chromosomes 7 and 11 to identify imprinted genes. Pubmed 1.043E-9 1.248E-7 9.285E-7 9.982E-7 3 19
9 2522449 Primary structure of a human small nuclear ribonucleoprotein polypeptide as deduced by cDNA analysis. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
10 9108119 Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
11 19095049 Developmentally dynamic changes of DNA methylation in the mouse Snurf/Snrpn gene. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
12 15615769 Epigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
13 10400982 Paternal deletion from Snrpn to Ube3a in the mouse causes hypotonia, growth retardation and partial lethality and provides evidence for a gene contributing to Prader-Willi syndrome. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
14 8363612 Isolation and structural characterization of the rat gene encoding the brain specific snRNP-associated polypeptide "N". Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
15 1303278 A candidate mouse model for Prader-Willi syndrome which shows an absence of Snrpn expression. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
16 12075010 Evidence for translational regulation of the imprinted Snurf-Snrpn locus in mice. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
17 10318933 An imprinted, mammalian bicistronic transcript encodes two independent proteins. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
18 11350123 The Prader-Willi syndrome imprinting center activates the paternally expressed murine Ube3a antisense transcript but represses paternal Ube3a. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
19 11431693 The SNRPN promoter is not required for genomic imprinting of the Prader-Willi/Angelman domain in mice. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
20 7581464 Deficiency of the beta 3 subunit of the type A gamma-aminobutyric acid receptor causes cleft palate in mice. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
21 18381202 Loss of methylation imprint of Snrpn in postovulatory aging mouse oocyte. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
22 8845846 Breakage in the SNRPN locus in a balanced 46,XY,t(15;19) Prader-Willi syndrome patient. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
23 2753153 Isolation of cDNA clones encoding the human Sm B/B' auto-immune antigen and specifically reacting with human anti-Sm auto-immune sera. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
24 10626556 Genetic abnormalities in Prader-Willi syndrome and lessons from mouse models. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
25 8571960 Gene structure, DNA methylation, and imprinted expression of the human SNRPN gene. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
26 1611213 The mouse pink-eyed dilution locus: a model for aspects of Prader-Willi syndrome, Angelman syndrome, and a form of hypomelanosis of Ito. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
27 16116039 Characterization of cis- and trans-acting elements in the imprinted human SNURF-SNRPN locus. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
28 21227640 Behavioral phenotype in adults with Prader-Willi syndrome. Pubmed 1.371E-8 4.686E-7 3.487E-6 1.312E-5 2 2
29 15226413 Regulation of the large (approximately 1000 kb) imprinted murine Ube3a antisense transcript by alternative exons upstream of Snurf/Snrpn. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
30 2528429 Expression of the major human ribonucleoprotein (RNP) autoantigens in Escherichia coli and their use in an EIA for screening sera from patients with autoimmune diseases. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
31 20808828 Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
32 12606284 Nonneuronal expression of the GABA(A) beta3 subunit gene is required for normal palate development in mice. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
33 15014980 SNURF-SNRPN and UBE3A transcript levels in patients with Angelman syndrome. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
34 12856284 Cloning, functional study and comparative mapping of Luzp2 to mouse chromosome 7 and human chromosome 11p13-11p14. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
35 2522186 A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B'. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
36 17262171 Analysis of candidate imprinted genes in PWS subjects with atypical genetics: a possible inactivating mutation in the SNURF/SNRPN minimal promoter. Pubmed 4.113E-8 1.093E-6 8.137E-6 3.936E-5 2 3
37 18361419 Transmission disequilibrium testing of the chromosome 15q11-q13 region in autism. Pubmed 8.226E-8 1.874E-6 1.395E-5 7.872E-5 2 4
38 9330366 GABAA-receptor alpha-subunit is an essential prerequisite for receptor formation in vivo. Pubmed 8.226E-8 1.874E-6 1.395E-5 7.872E-5 2 4
39 8146195 Phenotypic consequences of deletion of the gamma 3, alpha 5, or beta 3 subunit of the type A gamma-aminobutyric acid receptor in mice. Pubmed 8.226E-8 1.874E-6 1.395E-5 7.872E-5 2 4
40 8389469 Concordance between isolated cleft palate in mice and alterations within a region including the gene encoding the beta 3 subunit of the type A gamma-aminobutyric acid receptor. Pubmed 8.226E-8 1.874E-6 1.395E-5 7.872E-5 2 4
41 19471314 Expression of SNURF-SNRPN upstream transcripts and epigenetic regulatory genes during human spermatogenesis. Pubmed 8.226E-8 1.874E-6 1.395E-5 7.872E-5 2 4
42 8392662 A cluster of three GABAA receptor subunit genes is deleted in a neurological mutant of the mouse p locus. Pubmed 8.226E-8 1.874E-6 1.395E-5 7.872E-5 2 4
43 8001787 The original pink-eyed dilution mutation (p) arose in Asiatic mice: implications for the H4 minor histocompatibility antigen, Myod1 regulation and the origin of inbred strains. Pubmed 1.371E-7 2.915E-6 2.170E-5 1.312E-4 2 5
44 23609791 Recommendations for the investigation of animal models of Prader-Willi syndrome. Pubmed 1.371E-7 2.915E-6 2.170E-5 1.312E-4 2 5
45 11159938 A translocation breakpoint cluster disrupts the newly defined 3' end of the SNURF-SNRPN transcription unit on chromosome 15. Pubmed 1.371E-7 2.915E-6 2.170E-5 1.312E-4 2 5
46 25300248 Imprinting analysis of the mouse chromosome 7C region in DNMT1-null embryos. Pubmed 2.056E-7 4.100E-6 3.051E-5 1.968E-4 2 6
47 9682826 Independent assembly and subcellular targeting of GABA(A)-receptor subtypes demonstrated in mouse hippocampal and olfactory neurons in vivo. Pubmed 2.056E-7 4.100E-6 3.051E-5 1.968E-4 2 6
48 8095339 Evaluation of potential models for imprinted and nonimprinted components of human chromosome 15q11-q13 syndromes by fine-structure homology mapping in the mouse. Pubmed 2.056E-7 4.100E-6 3.051E-5 1.968E-4 2 6
49 8601493 Complementation analyses for 45 mutations encompassing the pink-eyed dilution (p) locus of the mouse. Pubmed 4.934E-7 9.637E-6 7.171E-5 4.722E-4 2 9
50 21343540 Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome. Pubmed 1.247E-6 2.340E-5 1.741E-4 1.193E-3 2 14
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 370 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:EAPP EAPP interactions 8.415E-5 3.114E-2
2.021E-1
 3.114E-2 2 52
2 int:BPY2B BPY2B interactions 5.648E-4 3.693E-2
2.397E-1
2.090E-1
 1 2
3 int:BPY2C BPY2C interactions 8.471E-4 3.693E-2
2.397E-1
3.134E-1
 1 3
4 int:BPY2 BPY2 interactions 8.471E-4 3.693E-2
2.397E-1
3.134E-1
 1 3
5 int:AFG3L1P AFG3L1P interactions 8.471E-4 3.693E-2
2.397E-1
3.134E-1
 1 3
6 int:OCA2 OCA2 interactions 1.129E-3 3.693E-2
2.397E-1
4.179E-1
 1 4
7 int:TAT TAT interactions 1.412E-3 3.693E-2
2.397E-1
5.223E-1
 1 5
8 int:IGLC7 IGLC7 interactions 1.412E-3 3.693E-2
2.397E-1
5.223E-1
 1 5
9 int:MDM1 MDM1 interactions 1.412E-3 3.693E-2
2.397E-1
5.223E-1
 1 5
10 int:PRMT5 PRMT5 interactions 1.666E-3 3.693E-2
2.397E-1
6.165E-1
 2 232
11 int:SNURF SNURF interactions 1.694E-3 3.693E-2
2.397E-1
6.267E-1
 1 6
12 int:PDE1B PDE1B interactions 1.694E-3 3.693E-2
2.397E-1
6.267E-1
 1 6
13 int:PHKG1 PHKG1 interactions 1.694E-3 3.693E-2
2.397E-1
6.267E-1
 1 6
14 int:SPINK1 SPINK1 interactions 1.694E-3 3.693E-2
2.397E-1
6.267E-1
 1 6
15 int:UBQLN1 UBQLN1 interactions 1.811E-3 3.693E-2
2.397E-1
6.701E-1
 2 242
16 int:MEOX2 MEOX2 interactions 1.962E-3 3.693E-2
2.397E-1
7.259E-1
 2 252
17 int:SERHL2 SERHL2 interactions 1.976E-3 3.693E-2
2.397E-1
7.310E-1
 1 7
18 int:AHSP AHSP interactions 2.258E-3 3.693E-2
2.397E-1
8.354E-1
 1 8
19 int:PRKACA PRKACA interactions 2.467E-3 3.693E-2
2.397E-1
9.127E-1
 2 283
20 int:GABRB2 GABRB2 interactions 2.540E-3 3.693E-2
2.397E-1
9.397E-1
 1 9
21 int:CMTR2 CMTR2 interactions 2.540E-3 3.693E-2
2.397E-1
9.397E-1
 1 9
22 int:TTC23L TTC23L interactions 2.822E-3 3.693E-2
2.397E-1
1.000E0
 1 10
23 int:ARHGEF15 ARHGEF15 interactions 3.103E-3 3.693E-2
2.397E-1
1.000E0
 1 11
24 int:GABRA6 GABRA6 interactions 3.385E-3 3.693E-2
2.397E-1
1.000E0
 1 12
25 int:HPCAL4 HPCAL4 interactions 3.385E-3 3.693E-2
2.397E-1
1.000E0
 1 12
26 int:MAGEA8 MAGEA8 interactions 3.385E-3 3.693E-2
2.397E-1
1.000E0
 1 12
27 int:NOMO2 NOMO2 interactions 3.385E-3 3.693E-2
2.397E-1
1.000E0
 1 12
28 int:PRAG1 PRAG1 interactions 3.667E-3 3.693E-2
2.397E-1
1.000E0
 1 13
29 int:SNRNP48 SNRNP48 interactions 3.667E-3 3.693E-2
2.397E-1
1.000E0
 1 13
30 int:GABRB3 GABRB3 interactions 3.948E-3 3.693E-2
2.397E-1
1.000E0
 1 14
31 int:TANGO6 TANGO6 interactions 3.948E-3 3.693E-2
2.397E-1
1.000E0
 1 14
32 int:AFTPH AFTPH interactions 4.230E-3 3.693E-2
2.397E-1
1.000E0
 1 15
33 int:PIPSL PIPSL interactions 4.230E-3 3.693E-2
2.397E-1
1.000E0
 1 15
34 int:GPATCH11 GPATCH11 interactions 4.230E-3 3.693E-2
2.397E-1
1.000E0
 1 15
35 int:CELA2B CELA2B interactions 4.511E-3 3.693E-2
2.397E-1
1.000E0
 1 16
36 int:PRKRIP1 PRKRIP1 interactions 4.511E-3 3.693E-2
2.397E-1
1.000E0
 1 16
37 int:MNT MNT interactions 4.793E-3 3.693E-2
2.397E-1
1.000E0
 1 17
38 int:TCF19 TCF19 interactions 4.793E-3 3.693E-2
2.397E-1
1.000E0
 1 17
39 int:LARP7 LARP7 interactions 4.963E-3 3.693E-2
2.397E-1
1.000E0
 2 404
40 int:NOL7 NOL7 interactions 5.074E-3 3.693E-2
2.397E-1
1.000E0
 1 18
41 int:ARC ARC interactions 5.074E-3 3.693E-2
2.397E-1
1.000E0
 1 18
42 int:SACS SACS interactions 5.074E-3 3.693E-2
2.397E-1
1.000E0
 1 18
43 int:SKAP2 SKAP2 interactions 5.074E-3 3.693E-2
2.397E-1
1.000E0
 1 18
44 int:SNRNP35 SNRNP35 interactions 5.074E-3 3.693E-2
2.397E-1
1.000E0
 1 18
45 int:ASAP3 ASAP3 interactions 5.355E-3 3.693E-2
2.397E-1
1.000E0
 1 19
46 int:POLE4 POLE4 interactions 5.355E-3 3.693E-2
2.397E-1
1.000E0
 1 19
47 int:LCN1 LCN1 interactions 5.355E-3 3.693E-2
2.397E-1
1.000E0
 1 19
48 int:FUZ FUZ interactions 5.637E-3 3.693E-2
2.397E-1
1.000E0
 1 20
49 int:PAX5 PAX5 interactions 5.637E-3 3.693E-2
2.397E-1
1.000E0
 1 20
50 int:AKAP7 AKAP7 interactions 5.637E-3 3.693E-2
2.397E-1
1.000E0
 1 20
Show 45 more annotations

10: Cytoband [Display Chart] 4 input genes in category / 2 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 15q12 15q12 3.595E-7 7.190E-7 1.078E-6 7.190E-7 2 9
2 15q11.2 15q11.2 1.616E-4 1.616E-4 2.424E-4 3.232E-4 2 181

11: Transcription Factor Binding Site [Display Chart] 4 input genes in category / 49 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$YY1 Q6 V$YY1 Q6 2.509E-5 1.229E-3 5.507E-3 1.229E-3 3 182

12: Gene Family [Display Chart] 1 input genes in category / 1 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 563 Gamma-aminobutyric acid type A receptor subunits genenames.org 1.044E-3 1.044E-3 1.044E-3 1.044E-3 1 19

13: Coexpression [Display Chart] 5 input genes in category / 308 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16319131-table1 Human StemCell Sun06 32genes GeneSigDB 9.793E-9 3.016E-6 1.903E-5 3.016E-6 3 24
2 M2491 List of genomically imprinted genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.916E-7 2.951E-5 1.862E-4 5.903E-5 3 63
3 M1726 Transcripts showing subcellular localization only to proximal dendrites in the adult mouse brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.481E-5 2.547E-3 1.607E-2 7.641E-3 2 37
4 12925741-Figure8 Human Lymphoma Jenner03 279genes GeneSigDB 4.288E-4 2.814E-2
1.775E-1
1.321E-1
 2 153
5 M8346 Genes down-regulated in germinal center B lymphocytes: wildtype versus ZBTB7A [GeneID=51341] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 2.814E-2
1.775E-1
2.207E-1
 2 198
6 M3245 Genes up-regulated in comparison of naive B cells versus memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 2.814E-2
1.775E-1
2.207E-1
 2 198
7 M4111 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h versus those stimulated at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.814E-2
1.775E-1
2.251E-1
 2 200
8 M6306 Genes up-regulated in control macrophages: untreated versus primed by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.814E-2
1.775E-1
2.251E-1
 2 200
Show 3 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 415 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Excitatory Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Excitatory Top 200 Genes BrainMap 2.620E-5 1.087E-2
7.183E-2
 1.087E-2 3 304
2 Facebase RNAseq e10.5 Neural Epithelium Overlying Medial Eminence 500 K5 FacebaseRNAseq e10.5 Neural Epithelium Overlying Medial Eminence top-relative-expression-ranked 500 k-means-cluster#5 FaceBase_RNAseq 5.978E-5 1.121E-2
7.406E-2
 2.481E-2 2 54
3 Facebase RNAseq e10.5 Neural Epithelium Overlying Medial Eminence 500 FacebaseRNAseq e10.5 Neural Epithelium Overlying Medial Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 1.035E-4 1.121E-2
7.406E-2
 4.296E-2 3 482
4 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 500 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 500 FaceBase_RNAseq 1.080E-4 1.121E-2
7.406E-2
 4.484E-2 3 489
5 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal VHL RCC Junk/Kidney Normal VHL RCC IN17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal VHL RCC Junk/Kidney Normal VHL RCC IN17 Adult, Development, and Cancer types 1.978E-4 1.358E-2
8.972E-2
8.207E-2
 2 98
6 Facebase RNAseq e8.5 Floor Plate 100 FacebaseRNAseq e8.5 Floor Plate top-relative-expression-ranked 100 FaceBase_RNAseq 2.018E-4 1.358E-2
8.972E-2
8.375E-2
 2 99
7 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Adenocarcinoma Mixed Subtype/1/3 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Adenocarcinoma Mixed Subtype/1/3 TCGA-Lung 2.291E-4 1.358E-2
8.972E-2
9.506E-2
 1 1
8 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k1 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.216E-4 1.531E-2
1.011E-1
1.335E-1
 2 125
9 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 1000 K1 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 1000 k-means-cluster#1 FaceBase_RNAseq 3.320E-4 1.531E-2
1.011E-1
1.378E-1
 2 127
10 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 500 K2 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 500 k-means-cluster#2 FaceBase_RNAseq 4.325E-4 1.795E-2
1.186E-1
1.795E-1
 2 145
11 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 200 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 5.937E-4 2.240E-2
1.480E-1
2.464E-1
 2 170
12 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Overall Top 200 Genes BrainMap 6.800E-4 2.352E-2
1.554E-1
2.822E-1
 2 182
13 gudmap dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 200 dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 7.721E-4 2.465E-2
1.628E-1
3.204E-1
 2 194
14 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 2500 K5 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 2500 k-means-cluster#5 FaceBase_RNAseq 8.615E-4 2.524E-2
1.667E-1
3.575E-1
 2 205
15 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k1 1000 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 9.123E-4 2.524E-2
1.667E-1
3.786E-1
 2 211
16 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 1000 K2 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 1000 k-means-cluster#2 FaceBase_RNAseq 1.257E-3 3.086E-2
2.039E-1
5.216E-1
 2 248
17 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Granule Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Granule Top 200 Genes BrainMap 1.277E-3 3.086E-2
2.039E-1
5.300E-1
 2 250
18 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Cholinergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Cholinergic Top 200 Genes BrainMap 1.338E-3 3.086E-2
2.039E-1
5.554E-1
 2 256
19 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Serotonergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Serotonergic Top 200 Genes BrainMap 1.531E-3 3.200E-2
2.114E-1
6.354E-1
 2 274
20 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Inhibitory Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Inhibitory Top 200 Genes BrainMap 1.542E-3 3.200E-2
2.114E-1
6.400E-1
 2 275
21 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Noradrenergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Noradrenergic Top 200 Genes BrainMap 1.655E-3 3.271E-2
2.161E-1
6.869E-1
 2 285
22 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-peptidergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-peptidergic Top 200 Genes BrainMap 1.772E-3 3.327E-2
2.198E-1
7.353E-1
 2 295
23 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Neurofilament Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Neurofilament Top 200 Genes BrainMap 1.844E-3 3.327E-2
2.198E-1
7.652E-1
 2 301
24 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Interneuron-selective Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Interneuron-selective Top 200 Genes BrainMap 2.017E-3 3.415E-2
2.256E-1
8.370E-1
 2 315
25 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Dopaminergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Dopaminergic Top 200 Genes BrainMap 2.068E-3 3.415E-2
2.256E-1
8.581E-1
 2 319
26 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuroblast Neuroblast Subtype VGLUT1,VGLUT2 Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuroblast Neuroblast Subtype VGLUT1,VGLUT2 Top 200 Genes BrainMap 2.251E-3 3.415E-2
2.256E-1
9.340E-1
 2 333
27 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Nitrergic enteric Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Nitrergic enteric Top 200 Genes BrainMap 2.400E-3 3.415E-2
2.256E-1
9.958E-1
 2 344
28 Kidney10XCellRanger Six2TGC TSC1 E14 NPC NPC Subtype E14-Six2TGC Tsc1-NPCA-C9-KC10 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 NPC NPC Subtype E14-Six2TGC Tsc1-NPCA-C9-KC10 Top 200 Genes 2.413E-3 3.415E-2
2.256E-1
1.000E0
 2 345
29 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Peptidergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Peptidergic Top 200 Genes BrainMap 2.441E-3 3.415E-2
2.256E-1
1.000E0
 2 347
30 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype R-LM border Cck inter Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype R-LM border Cck inter Top 200 Genes BrainMap 2.469E-3 3.415E-2
2.256E-1
1.000E0
 2 349
31 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-border Cck inter Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-border Cck inter Top 200 Genes BrainMap 2.553E-3 3.418E-2
2.258E-1
1.000E0
 2 355
32 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Subtype iNb2 Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Subtype iNb2 Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 2.697E-3 3.497E-2
2.311E-1
1.000E0
 2 365
33 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 2.800E-3 3.521E-2
2.326E-1
1.000E0
 2 372
34 Facebase RNAseq e8.5 Floor Plate 2500 K2 FacebaseRNAseq e8.5 Floor Plate top-relative-expression-ranked 2500 k-means-cluster#2 FaceBase_RNAseq 3.150E-3 3.798E-2
2.509E-1
1.000E0
 2 395
35 gudmap developingGonad e11.5 testes and mesonephros k1 100 DevelopingGonad e11.5 testes and mesonephros emap-3226 k-means-cluster#1 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 3.203E-3 3.798E-2
2.509E-1
1.000E0
 1 14
36 gudmap developingGonad e14.5 testes 500 k3 DevelopingGonad e14.5 testes emap-6710 k-means-cluster#3 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.431E-3 3.936E-2
2.600E-1
1.000E0
 1 15
37 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 500 DevelopingLowerUrinaryTract e14.5 bladder emap-6668 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.587E-3 3.936E-2
2.600E-1
1.000E0
 2 422
38 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 500 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.604E-3 3.936E-2
2.600E-1
1.000E0
 2 423
39 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Top 200 GSE76381_iPSMoleculeCountsPMLog2 3.824E-3 3.959E-2
2.615E-1
1.000E0
 2 436
40 gudmap developingGonad e12.5 testes k4 200 DevelopingGonad e12.5 testes emap-29069 k-means-cluster#4 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 3.888E-3 3.959E-2
2.615E-1
1.000E0
 1 17
41 gudmap dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 500 dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.911E-3 3.959E-2
2.615E-1
1.000E0
 2 441
42 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal VHL RCC Junk/Kidney Normal VHL RCC IN18 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal VHL RCC Junk/Kidney Normal VHL RCC IN18 Adult, Development, and Cancer types 4.573E-3 4.348E-2
2.873E-1
1.000E0
 1 20
43 Facebase RNAseq e10.5 Neural Epithelium Overlying Lateral Eminence 500 FacebaseRNAseq e10.5 Neural Epithelium Overlying Lateral Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 4.885E-3 4.348E-2
2.873E-1
1.000E0
 2 494
44 Facebase RNAseq e8.5 Floor Plate 500 FacebaseRNAseq e8.5 Floor Plate top-relative-expression-ranked 500 FaceBase_RNAseq 4.904E-3 4.348E-2
2.873E-1
1.000E0
 2 495
45 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 500 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 500 FaceBase_RNAseq 4.923E-3 4.348E-2
2.873E-1
1.000E0
 2 496
46 PCBC SC blastocyst 500 Progenitor-Cell-Biology-Consortium StemCell fromBlastocyst-derived-humanEmbryonicStemCells top-relative-expression-ranked 500 PCBC 4.943E-3 4.348E-2
2.873E-1
1.000E0
 2 497
47 gudmap dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 k4 100 dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 100 Gudmap Mouse ST 1.0 5.029E-3 4.348E-2
2.873E-1
1.000E0
 1 22
48 gudmap developingGonad e18.5 testes 1000 k2 DevelopingGonad e18.5 testes emap-11164 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.029E-3 4.348E-2
2.873E-1
1.000E0
 1 22
Show 43 more annotations

15: Computational [Display Chart] 4 input genes in category / 15 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M6383 MODULE 415 Genes in the cancer module 415. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.172E-3 4.474E-2
1.485E-1
7.757E-2
 1 13
2 M3806 MODULE 215 Neurotransmitter (GABA) receptor. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.965E-3 4.474E-2
1.485E-1
8.948E-2
 1 15

16: MicroRNA [Display Chart] 5 input genes in category / 258 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-563:mirSVR highEffct hsa-miR-563:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.119E-6 2.888E-4 1.771E-3 2.888E-4 3 350
2 hsa-miR-1225-5p:PITA hsa-miR-1225-5p:PITA TOP PITA 1.430E-5 1.845E-3 1.131E-2 3.690E-3 2 87
3 hsa-miR-1274a:PITA hsa-miR-1274a:PITA TOP PITA 4.152E-5 3.571E-3 2.190E-2 1.071E-2 2 148
4 TTTTGAG,MIR-373:MSigDB TTTTGAG,MIR-373:MSigDB MSigDB 8.522E-5 4.656E-3 2.855E-2 2.199E-2 2 212
5 hsa-miR-513c:PITA hsa-miR-513c:PITA TOP PITA 1.038E-4 4.656E-3 2.855E-2 2.678E-2 2 234
6 hsa-miR-1184:PITA hsa-miR-1184:PITA TOP PITA 1.083E-4 4.656E-3 2.855E-2 2.794E-2 2 239
7 hsa-miR-1244:PITA hsa-miR-1244:PITA TOP PITA 1.301E-4 4.795E-3 2.940E-2 3.356E-2 2 262
8 hsa-miR-557:PITA hsa-miR-557:PITA TOP PITA 1.750E-4 5.018E-3 3.077E-2 4.516E-2 2 304
9 hsa-miR-507:PITA hsa-miR-507:PITA TOP PITA 1.750E-4 5.018E-3 3.077E-2 4.516E-2 2 304
10 hsa-miR-499-3p:PITA hsa-miR-499-3p:PITA TOP PITA 2.253E-4 5.478E-3 3.359E-2
5.812E-2
 2 345
11 hsa-miR-4283:mirSVR highEffct hsa-miR-4283:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.345E-4 5.478E-3 3.359E-2
6.049E-2
 2 352
12 hsa-miR-380*:mirSVR highEffct hsa-miR-380*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.548E-4 5.478E-3 3.359E-2
6.574E-2
 2 367
13 hsa-miR-587:PITA hsa-miR-587:PITA TOP PITA 3.255E-4 6.283E-3 3.853E-2
8.397E-2
 2 415
14 hsa-miR-105:PITA hsa-miR-105:PITA TOP PITA 3.542E-4 6.283E-3 3.853E-2
9.138E-2
 2 433
15 hsa-miR-802:PITA hsa-miR-802:PITA TOP PITA 3.858E-4 6.283E-3 3.853E-2
9.953E-2
 2 452
16 hsa-miR-654-5p:mirSVR highEffct hsa-miR-654-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.187E-4 6.283E-3 3.853E-2
1.080E-1
 2 471
17 hsa-miR-4304:mirSVR lowEffct hsa-miR-4304:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.312E-4 6.283E-3 3.853E-2
1.112E-1
 2 478
18 hsa-miR-541:mirSVR highEffct hsa-miR-541:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.384E-4 6.283E-3 3.853E-2
1.131E-1
 2 482
19 hsa-miR-652:PITA hsa-miR-652:PITA TOP PITA 1.245E-3 1.691E-2
1.037E-1
3.213E-1
 1 18
20 hsa-miR-566:PITA hsa-miR-566:PITA TOP PITA 1.384E-3 1.785E-2
1.094E-1
3.570E-1
 1 20
21 hsa-miR-424-3p:Functional MTI Functional MTI miRTarbase 2.213E-3 2.719E-2
1.667E-1
5.709E-1
 1 32
22 hsa-miR-3186-3p:mirSVR highEffct hsa-miR-3186-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.351E-3 2.757E-2
1.691E-1
6.066E-1
 1 34
23 hsa-miR-563:PITA hsa-miR-563:PITA TOP PITA 3.111E-3 2.877E-2
1.764E-1
8.026E-1
 1 45
24 TCTGATC,MIR-383:MSigDB TCTGATC,MIR-383:MSigDB MSigDB 3.249E-3 2.877E-2
1.764E-1
8.382E-1
 1 47
25 hsa-miR-4703-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 2.877E-2
1.764E-1
8.738E-1
 1 49
26 GTAAGAT,MIR-200A:MSigDB GTAAGAT,MIR-200A:MSigDB MSigDB 3.732E-3 2.877E-2
1.764E-1
9.629E-1
 1 54
27 GTACAGG,MIR-486:MSigDB GTACAGG,MIR-486:MSigDB MSigDB 3.801E-3 2.877E-2
1.764E-1
9.807E-1
 1 55
28 GGCACAT,MIR-455:MSigDB GGCACAT,MIR-455:MSigDB MSigDB 3.801E-3 2.877E-2
1.764E-1
9.807E-1
 1 55
29 GACAGGG,MIR-339:MSigDB GACAGGG,MIR-339:MSigDB MSigDB 4.284E-3 2.877E-2
1.764E-1
1.000E0
 1 62
30 hsa-miR-6853-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 2.877E-2
1.764E-1
1.000E0
 1 63
31 hsa-miR-663b:PITA hsa-miR-663b:PITA TOP PITA 4.491E-3 2.877E-2
1.764E-1
1.000E0
 1 65
32 hsa-miR-4782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.698E-3 2.877E-2
1.764E-1
1.000E0
 1 68
33 hsa-miR-5706:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.698E-3 2.877E-2
1.764E-1
1.000E0
 1 68
34 hsa-miR-1273h-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.767E-3 2.877E-2
1.764E-1
1.000E0
 1 69
35 hsa-miR-566:mirSVR highEffct hsa-miR-566:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.905E-3 2.877E-2
1.764E-1
1.000E0
 1 71
36 hsa-miR-1225-3p:PITA hsa-miR-1225-3p:PITA TOP PITA 4.974E-3 2.877E-2
1.764E-1
1.000E0
 1 72
37 hsa-miR-6802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.974E-3 2.877E-2
1.764E-1
1.000E0
 1 72
38 hsa-miR-1293:PITA hsa-miR-1293:PITA TOP PITA 5.111E-3 2.877E-2
1.764E-1
1.000E0
 1 74
39 hsa-miR-5007-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 2.877E-2
1.764E-1
1.000E0
 1 75
40 hsa-miR-3177-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 2.877E-2
1.764E-1
1.000E0
 1 75
41 hsa-miR-323-5p:PITA hsa-miR-323-5p:PITA TOP PITA 5.318E-3 2.877E-2
1.764E-1
1.000E0
 1 77
42 hsa-miR-541:PITA hsa-miR-541:PITA TOP PITA 5.387E-3 2.877E-2
1.764E-1
1.000E0
 1 78
43 hsa-miR-654-5p:PITA hsa-miR-654-5p:PITA TOP PITA 5.525E-3 2.877E-2
1.764E-1
1.000E0
 1 80
44 hsa-miR-339-5p:PITA hsa-miR-339-5p:PITA TOP PITA 5.663E-3 2.877E-2
1.764E-1
1.000E0
 1 82
45 hsa-miR-6739-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.663E-3 2.877E-2
1.764E-1
1.000E0
 1 82
46 hsa-miR-516b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.801E-3 2.877E-2
1.764E-1
1.000E0
 1 84
47 hsa-miR-541-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.869E-3 2.877E-2
1.764E-1
1.000E0
 1 85
48 hsa-miR-6784-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.869E-3 2.877E-2
1.764E-1
1.000E0
 1 85
49 hsa-miR-6862-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.007E-3 2.877E-2
1.764E-1
1.000E0
 1 87
50 hsa-miR-1227:PITA hsa-miR-1227:PITA TOP PITA 6.076E-3 2.877E-2
1.764E-1
1.000E0
 1 88
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 1057 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID005464545 chrysoin Stitch 7.186E-11 7.595E-8 5.728E-7 7.595E-8 4 46
2 CID000121958 m(7)GpppG Stitch 7.330E-9 3.874E-6 2.921E-5 7.747E-6 4 143
3 CID005287428 AC1NR9O8 Stitch 1.109E-7 3.909E-5 2.947E-4 1.173E-4 3 52
4 CID003522585 MHDA Stitch 2.107E-6 5.567E-4 4.198E-3 2.227E-3 2 11
5 CID000123268 lithium aluminate Stitch 1.148E-5 2.426E-3 1.830E-2 1.213E-2 2 25
6 CID000005224 NSC182856 Stitch 1.446E-5 2.547E-3 1.921E-2 1.528E-2 2 28
7 CID006852127 Asn-SA Stitch 2.145E-5 3.161E-3 2.383E-2 2.267E-2 2 34
8 CID000030623 ICRF-187 Stitch 2.687E-5 3.161E-3 2.383E-2 2.840E-2 2 38
9 CID000465394 N-(aminomethyl)succinamic acid Stitch 2.980E-5 3.161E-3 2.383E-2 3.150E-2 2 40
10 CID000062286 arsenals Stitch 3.133E-5 3.161E-3 2.383E-2 3.311E-2 2 41
11 CID000004120 N-methylscopolamine Stitch 3.289E-5 3.161E-3 2.383E-2 3.477E-2 2 42
12 CID000482125 5'-CG-3 Stitch 3.613E-5 3.183E-3 2.400E-2 3.819E-2 2 44
13 CID000008447 MBTS Stitch 4.128E-5 3.356E-3 2.531E-2 4.363E-2 2 47
14 CID000011122 methyl-1,4-benzoquinone Stitch 4.677E-5 3.531E-3 2.663E-2 4.943E-2 2 50
15 CID006480473 AC1O59H4 Stitch 5.667E-5 3.993E-3 3.011E-2
5.990E-2
 2 55
16 CID005326396 I-bB Stitch 7.212E-5 4.630E-3 3.492E-2
7.623E-2
 2 62
17 CID005244174 AC1NRNSN Stitch 7.447E-5 4.630E-3 3.492E-2
7.872E-2
 2 63
18 CID000435143 NSC-364372 Stitch 9.161E-5 5.147E-3 3.881E-2
9.683E-2
 3 484
19 CID000097370 benzoylphenylalanine Stitch 9.469E-5 5.147E-3 3.881E-2
1.001E-1
 2 71
20 CID000001210 Tubocurarine,d Stitch 9.739E-5 5.147E-3 3.881E-2
1.029E-1
 2 72
21 CID005360741 alternariol monomethyl ether Stitch 1.114E-4 5.354E-3 4.038E-2
1.178E-1
 2 77
22 CID000449572 AC1L9N9H Stitch 1.114E-4 5.354E-3 4.038E-2
1.178E-1
 2 77
23 CID000444773 PPL-L-alanine Stitch 1.264E-4 5.810E-3 4.381E-2
1.336E-1
 2 82
24 CID000001896 AC1L1CH3 Stitch 1.359E-4 5.984E-3 4.512E-2
1.436E-1
 2 85
25 CID000024572 lead arsenate Stitch 1.490E-4 6.299E-3 4.750E-2
1.575E-1
 2 89
26 CID004369512 AC1NA07U Stitch 1.698E-4 6.902E-3
5.205E-2
1.795E-1
 2 95
27 CID006914645 U1-1 Stitch 1.807E-4 7.074E-3
5.334E-2
1.910E-1
 2 98
28 CID006439158 AC1O5R3K Stitch 1.958E-4 7.390E-3
5.572E-2
2.069E-1
 2 102
29 ctd:D003548 Cysteinyldopa CTD 2.189E-4 7.464E-3
5.628E-2
2.314E-1
 1 1
30 DB00592 Piperazine Drug Bank 2.189E-4 7.464E-3
5.628E-2
2.314E-1
 1 1
31 ctd:C098123 3,3-bis(trifluoromethyl)bicyclo(2.2.1)heptane-2,2-dicarbonitrile CTD 2.189E-4 7.464E-3
5.628E-2
2.314E-1
 1 1
32 CID000008202 methyl 9-octadecenoate Stitch 2.360E-4 7.796E-3
5.879E-2
2.495E-1
 2 112
33 CID003386230 AC1MPJID Stitch 2.575E-4 8.249E-3
6.221E-2
2.722E-1
 2 117
34 CID000004004 malathion Stitch 2.664E-4 8.282E-3
6.246E-2
2.816E-1
 2 119
35 ctd:C000188 alachlor CTD 3.179E-4 9.600E-3
7.239E-2
3.360E-1
 2 130
36 CID000001486 2,4-dichlorophenoxyacetic acid Stitch 3.277E-4 9.622E-3
7.256E-2
3.464E-1
 2 132
37 CID000002145 aminoglutethimide Stitch 3.529E-4 1.008E-2
7.603E-2
3.731E-1
 2 137
38 CID000007965 cyclohexylammonium Stitch 4.062E-4 1.122E-2
8.458E-2
4.293E-1
 2 147
39 ctd:C030692 5,6-dihydroxy-2-indolylcarboxylic acid CTD 4.378E-4 1.122E-2
8.458E-2
4.627E-1
 1 2
40 CID010039403 JT6 Stitch 4.378E-4 1.122E-2
8.458E-2
4.627E-1
 1 2
41 DB00602 Ivermectin Drug Bank 4.378E-4 1.122E-2
8.458E-2
4.627E-1
 1 2
42 CID000024437 sodium bisulfite Stitch 4.457E-4 1.122E-2
8.458E-2
4.711E-1
 2 154
43 CID005287709 AC1NRA5C Stitch 5.684E-4 1.341E-2
1.011E-1
6.008E-1
 2 174
44 CID000018835 Ebna Stitch 6.284E-4 1.341E-2
1.011E-1
6.642E-1
 2 183
45 ctd:C021604 CL 218872 CTD 6.566E-4 1.341E-2
1.011E-1
6.940E-1
 1 3
46 5965 UP LY294002; Up 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.985E-4 1.341E-2
1.011E-1
7.383E-1
 2 193
47 6102 UP Leflunomide [75706-12-6]; Up 200; 14.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.057E-4 1.341E-2
1.011E-1
7.459E-1
 2 194
48 4658 UP Lorglumide sodium salt [97964-56-2]; Up 200; 8.4uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.349E-4 1.341E-2
1.011E-1
7.768E-1
 2 198
49 4609 UP Zimelidine dihydrochloride monohydrate [61129-30-4]; Up 200; 9.8uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.349E-4 1.341E-2
1.011E-1
7.768E-1
 2 198
50 7220 UP Estriol [50-27-1]; Up 200; 13.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.349E-4 1.341E-2
1.011E-1
7.768E-1
 2 198
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 309 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0162635 Angelman Syndrome DisGeNET Curated 6.953E-13 2.148E-10 1.356E-9 2.148E-10 5 62
2 C0032897 Prader-Willi Syndrome DisGeNET Curated 1.038E-11 1.603E-9 1.012E-8 3.206E-9 5 105
3 C1834690 Spinal Muscular Atrophy, Childhood, Proximal, Autosomal Dominant DisGeNET Curated 1.142E-6 8.821E-5 5.568E-4 3.529E-4 2 6
4 C0205882 Infections, Parvovirus DisGeNET BeFree 1.142E-6 8.821E-5 5.568E-4 3.529E-4 2 6
5 C0037933 Spinal Diseases DisGeNET BeFree 1.598E-6 9.879E-5 6.236E-4 4.939E-4 2 7
6 C1865384 Amyotrophy, monomelic DisGeNET Curated 2.131E-6 1.097E-4 6.928E-4 6.585E-4 2 8
7 C0917981 Progressive Muscular Atrophy DisGeNET BeFree 2.740E-6 1.209E-4 7.634E-4 8.465E-4 2 9
8 C0152109 Juvenile Spinal Muscular Atrophy DisGeNET Curated 4.184E-6 1.528E-4 9.643E-4 1.293E-3 2 11
9 C4024957 Proximal spinal muscular atrophy DisGeNET BeFree 5.021E-6 1.528E-4 9.643E-4 1.551E-3 2 12
10 C1535926 Neurodevelopmental Disorders DisGeNET Curated 5.221E-6 1.528E-4 9.643E-4 1.613E-3 3 132
11 C0270764 Motor Neuron Disease, Lower DisGeNET BeFree 5.933E-6 1.528E-4 9.643E-4 1.833E-3 2 13
12 C0751870 Heredodegenerative Disorders, Nervous System DisGeNET Curated 5.933E-6 1.528E-4 9.643E-4 1.833E-3 2 13
13 C0578626 blue iris (physical finding) DisGeNET Curated 1.034E-5 2.458E-4 1.551E-3 3.195E-3 2 17
14 C1511934 Differentiating Neuroblastoma DisGeNET BeFree 1.163E-5 2.567E-4 1.620E-3 3.594E-3 2 18
15 C3711376 Isodicentric Chromosome 15 Syndrome DisGeNET Curated 1.922E-5 3.959E-4 2.499E-3 5.939E-3 2 23
16 C0043116 HMN (Hereditary Motor Neuropathy) Proximal Type I DisGeNET Curated 2.665E-5 5.147E-4 3.249E-3 8.235E-3 2 27
17 C1876214 ALBINOIDISM, OCULOCUTANEOUS, AUTOSOMAL DOMINANT DisGeNET BeFree 3.082E-5 5.602E-4 3.536E-3 9.523E-3 2 29
18 C0026821 Muscle Cramp DisGeNET Curated 1.621E-4 2.509E-3 1.584E-2
5.009E-2
 2 66
19 C0010200 Coughing DisGeNET Curated 1.721E-4 2.509E-3 1.584E-2
5.318E-2
 2 68
20 C0162835 Hypopigmentation disorder DisGeNET Curated 1.930E-4 2.509E-3 1.584E-2
5.964E-2
 2 72
21 C1853237 Isolated cases DisGeNET Curated 2.095E-4 2.509E-3 1.584E-2
6.472E-2
 2 75
22 C0085655 Polymyositis DisGeNET Curated 2.266E-4 2.509E-3 1.584E-2
7.002E-2
 2 78
23 C0003886 Arthrogryposis DisGeNET Curated 2.444E-4 2.509E-3 1.584E-2
7.551E-2
 2 81
24 C0033626 Protein Deficiency DisGeNET Curated 2.505E-4 2.509E-3 1.584E-2
7.739E-2
 2 82
25 C1285162 Degenerative disorder DisGeNET BeFree 2.566E-4 2.509E-3 1.584E-2
7.929E-2
 2 83
26 C4024896 Motor neuron atrophy DisGeNET BeFree 3.085E-4 2.509E-3 1.584E-2
9.532E-2
 2 91
27 C1837650 Lack of spontaneous play DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
28 cv:C2677087 Epilepsy, childhood absence 5 Clinical Variations 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
29 cv:C0004352 Autistic disorder of childhood onset Clinical Variations 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
30 C1837649 Impaired ability to form peer relationships DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
31 C1837653 Inflexible adherence to routines or rituals DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
32 C1334682 Mediastinal Teratoma DisGeNET BeFree 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
33 C2677087 EPILEPSY, CHILDHOOD ABSENCE, SUSCEPTIBILITY TO, 5 DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
34 C0795858 Chromosome 15q, trisomy DisGeNET BeFree 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
35 C0877243 Serum serotonin increased DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
36 C2675336 Duplication 15q11-q13 Syndrome DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
37 C4021798 Impaired use of nonverbal behaviors DisGeNET Curated 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
38 OMIN:612269 EPILEPSY, CHILDHOOD ABSENCE, SUSCEPTIBILITY TO, 5; ECA5 OMIM 3.085E-4 2.509E-3 1.584E-2
9.534E-2
 1 1
39 C0027868 Neuromuscular Diseases DisGeNET Curated 3.433E-4 2.720E-3 1.717E-2
1.061E-1
 2 96
40 C0151611 Electroencephalogram abnormal DisGeNET Curated 3.951E-4 3.052E-3 1.927E-2
1.221E-1
 2 103
41 C0030552 Paresis DisGeNET Curated 4.588E-4 3.458E-3 2.182E-2
1.418E-1
 2 111
42 C0454644 Delayed speech and language development DisGeNET Curated 5.009E-4 3.467E-3 2.188E-2
1.548E-1
 2 116
43 C0023012 Language Delay DisGeNET Curated 5.009E-4 3.467E-3 2.188E-2
1.548E-1
 2 116
44 C0233715 Speech impairment DisGeNET Curated 5.009E-4 3.467E-3 2.188E-2
1.548E-1
 2 116
45 C0085084 Motor Neuron Disease DisGeNET Curated 5.096E-4 3.467E-3 2.188E-2
1.575E-1
 2 117
46 C0014060 Encephalitis, St. Louis DisGeNET BeFree 5.539E-4 3.467E-3 2.188E-2
1.712E-1
 2 122
47 C0035372 Rett Syndrome DisGeNET Curated 6.001E-4 3.467E-3 2.188E-2
1.854E-1
 2 127
48 C0241210 Speech Delay DisGeNET Curated 6.095E-4 3.467E-3 2.188E-2
1.883E-1
 2 128
49 OMIN:601800 SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 3; SHEP3 OMIM 6.170E-4 3.467E-3 2.188E-2
1.907E-1
 1 2
50 C0268503 Autosomal recessive ocular albinism DisGeNET BeFree 6.170E-4 3.467E-3 2.188E-2
1.907E-1
 1 2
Show 45 more annotations