Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc308_10, positive side

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1: GO: Molecular Function [Display Chart] 10 input genes in category / 65 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0070679 inositol 1,4,5 trisphosphate binding 8.717E-12 5.666E-10 2.697E-9 5.666E-10 4 10
2 GO:0015279 store-operated calcium channel activity 2.054E-11 6.675E-10 3.177E-9 1.335E-9 4 12
3 GO:0043178 alcohol binding 2.511E-7 4.382E-6 2.086E-5 1.632E-5 4 112
4 GO:0005262 calcium channel activity 2.697E-7 4.382E-6 2.086E-5 1.753E-5 4 114
5 GO:0015085 calcium ion transmembrane transporter activity 4.860E-7 6.318E-6 3.007E-5 3.159E-5 4 132
6 GO:0072509 divalent inorganic cation transmembrane transporter activity 1.434E-6 1.554E-5 7.396E-5 9.324E-5 4 173
7 GO:0030276 clathrin binding 4.982E-6 4.626E-5 2.202E-4 3.238E-4 3 66
8 GO:0035591 signaling adaptor activity 8.254E-6 6.706E-5 3.192E-4 5.365E-4 3 78
9 GO:0005261 cation channel activity 1.377E-5 9.947E-5 4.734E-4 8.953E-4 4 306
10 GO:0005216 ion channel activity 4.951E-5 2.980E-4 1.418E-3 3.218E-3 4 424
11 GO:0046873 metal ion transmembrane transporter activity 5.042E-5 2.980E-4 1.418E-3 3.277E-3 4 426
12 GO:0022838 substrate-specific channel activity 5.619E-5 3.044E-4 1.449E-3 3.653E-3 4 438
13 GO:0015267 channel activity 7.395E-5 3.252E-4 1.548E-3 4.807E-3 4 470
14 GO:0022803 passive transmembrane transporter activity 7.457E-5 3.252E-4 1.548E-3 4.847E-3 4 471
15 GO:0030674 protein binding, bridging 7.506E-5 3.252E-4 1.548E-3 4.879E-3 3 163
16 GO:0060090 molecular adaptor activity 1.024E-4 4.161E-4 1.981E-3 6.658E-3 3 181
17 GO:0042805 actinin binding 1.613E-4 6.166E-4 2.934E-3 1.048E-2 2 36
18 GO:0005070 SH3/SH2 adaptor activity 3.644E-4 1.316E-3 6.263E-3 2.369E-2 2 54
19 GO:0051117 ATPase binding 9.437E-4 3.228E-3 1.536E-2
6.134E-2
 2 87
20 GO:0005150 interleukin-1, type I receptor binding 1.071E-3 3.482E-3 1.657E-2
6.965E-2
 1 2
21 GO:0017124 SH3 domain binding 1.873E-3 5.798E-3 2.760E-2
1.218E-1
 2 123
22 GO:0098748 endocytic adaptor activity 4.814E-3 1.304E-2
6.205E-2
3.129E-1
 1 9
23 GO:0035615 clathrin adaptor activity 4.814E-3 1.304E-2
6.205E-2
3.129E-1
 1 9
24 GO:0035325 Toll-like receptor binding 4.814E-3 1.304E-2
6.205E-2
3.129E-1
 1 9
25 GO:0035612 AP-2 adaptor complex binding 5.347E-3 1.390E-2
6.617E-2
3.476E-1
 1 10
26 GO:0032183 SUMO binding 8.011E-3 2.003E-2
9.532E-2
5.207E-1
 1 15
27 GO:0001784 phosphotyrosine residue binding 9.606E-3 2.230E-2
1.061E-1
6.244E-1
 1 18
28 GO:0050750 low-density lipoprotein particle receptor binding 9.606E-3 2.230E-2
1.061E-1
6.244E-1
 1 18
29 GO:0005149 interleukin-1 receptor binding 1.067E-2 2.391E-2
1.138E-1
6.935E-1
 1 20
30 GO:0070325 lipoprotein particle receptor binding 1.226E-2 2.656E-2
1.264E-1
7.969E-1
 1 23
31 GO:0030159 receptor signaling complex scaffold activity 1.385E-2 2.904E-2
1.382E-1
9.002E-1
 1 26
32 GO:0045309 protein phosphorylated amino acid binding 1.491E-2 3.028E-2
1.441E-1
9.690E-1
 1 28
33 GO:0005227 calcium activated cation channel activity 1.596E-2 3.144E-2
1.497E-1
1.000E0
 1 30
34 GO:0045296 cadherin binding 1.702E-2 3.243E-2
1.544E-1
1.000E0
 1 32
35 GO:0031624 ubiquitin conjugating enzyme binding 1.755E-2 3.243E-2
1.544E-1
1.000E0
 1 33
36 GO:0042169 SH2 domain binding 1.808E-2 3.243E-2
1.544E-1
1.000E0
 1 34
37 GO:0044390 ubiquitin-like protein conjugating enzyme binding 1.913E-2 3.243E-2
1.544E-1
1.000E0
 1 36
38 GO:0001540 amyloid-beta binding 1.913E-2 3.243E-2
1.544E-1
1.000E0
 1 36
39 GO:0003779 actin binding 1.946E-2 3.243E-2
1.544E-1
1.000E0
 2 412
40 GO:0022839 ion gated channel activity 2.386E-2 3.877E-2
1.845E-1
1.000E0
 1 45
41 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding 3.118E-2 4.943E-2
2.352E-1
1.000E0
 1 59
Show 36 more annotations

2: GO: Biological Process [Display Chart] 9 input genes in category / 201 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006828 manganese ion transport 5.969E-11 1.200E-8 7.058E-8 1.200E-8 4 17
2 GO:0000041 transition metal ion transport 1.883E-7 1.893E-5 1.113E-4 3.785E-5 4 118
3 GO:0070588 calcium ion transmembrane transport 5.218E-6 3.496E-4 2.057E-3 1.049E-3 4 271
4 GO:0051480 regulation of cytosolic calcium ion concentration 8.440E-6 4.241E-4 2.495E-3 1.696E-3 4 306
5 GO:0006816 calcium ion transport 2.547E-5 6.908E-4 4.064E-3 5.119E-3 4 405
6 GO:0006874 cellular calcium ion homeostasis 2.698E-5 6.908E-4 4.064E-3 5.423E-3 4 411
7 GO:0050774 negative regulation of dendrite morphogenesis 2.813E-5 6.908E-4 4.064E-3 5.654E-3 2 17
8 GO:0055074 calcium ion homeostasis 3.077E-5 6.908E-4 4.064E-3 6.185E-3 4 425
9 GO:0072503 cellular divalent inorganic cation homeostasis 3.371E-5 6.908E-4 4.064E-3 6.775E-3 4 435
10 GO:0070838 divalent metal ion transport 4.020E-5 6.908E-4 4.064E-3 8.080E-3 4 455
11 GO:0072507 divalent inorganic cation homeostasis 4.124E-5 6.908E-4 4.064E-3 8.290E-3 4 458
12 GO:0072511 divalent inorganic cation transport 4.124E-5 6.908E-4 4.064E-3 8.290E-3 4 458
13 GO:0010800 positive regulation of peptidyl-threonine phosphorylation 8.372E-5 1.294E-3 7.615E-3 1.683E-2 2 29
14 GO:2000171 negative regulation of dendrite development 1.155E-4 1.659E-3 9.759E-3 2.322E-2 2 34
15 GO:0010799 regulation of peptidyl-threonine phosphorylation 1.686E-4 2.185E-3 1.285E-2 3.389E-2 2 41
16 GO:0051924 regulation of calcium ion transport 1.739E-4 2.185E-3 1.285E-2 3.496E-2 3 243
17 GO:0007204 positive regulation of cytosolic calcium ion concentration 2.641E-4 3.123E-3 1.837E-2
5.309E-2
 3 280
18 GO:0010959 regulation of metal ion transport 6.169E-4 6.888E-3 4.052E-2
1.240E-1
 3 374
19 GO:0018107 peptidyl-threonine phosphorylation 7.603E-4 7.958E-3 4.682E-2
1.528E-1
 2 87
20 GO:0048814 regulation of dendrite morphogenesis 7.955E-4 7.958E-3 4.682E-2
1.599E-1
 2 89
21 GO:0018210 peptidyl-threonine modification 8.314E-4 7.958E-3 4.682E-2
1.671E-1
 2 91
22 GO:0010615 positive regulation of cardiac muscle adaptation 9.663E-4 8.093E-3 4.761E-2
1.942E-1
 1 2
23 GO:1903244 positive regulation of cardiac muscle hypertrophy in response to stress 9.663E-4 8.093E-3 4.761E-2
1.942E-1
 1 2
24 GO:0090118 receptor-mediated endocytosis involved in cholesterol transport 9.663E-4 8.093E-3 4.761E-2
1.942E-1
 1 2
25 GO:1902630 regulation of membrane hyperpolarization 1.449E-3 1.150E-2
6.763E-2
2.913E-1
 1 3
26 GO:0051928 positive regulation of calcium ion transport 1.487E-3 1.150E-2
6.763E-2
2.989E-1
 2 122
27 GO:0010771 negative regulation of cell morphogenesis involved in differentiation 1.686E-3 1.255E-2
7.383E-2
3.389E-1
 2 130
28 GO:0048813 dendrite morphogenesis 2.007E-3 1.391E-2
8.182E-2
4.033E-1
 2 142
29 GO:0007338 single fertilization 2.007E-3 1.391E-2
8.182E-2
4.033E-1
 2 142
30 GO:0050773 regulation of dendrite development 2.236E-3 1.488E-2
8.753E-2
4.493E-1
 2 150
31 GO:0010977 negative regulation of neuron projection development 2.295E-3 1.488E-2
8.753E-2
4.612E-1
 2 152
32 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress 2.414E-3 1.516E-2
8.921E-2
4.853E-1
 1 5
33 GO:0030168 platelet activation 2.794E-3 1.663E-2
9.786E-2
5.615E-1
 2 168
34 GO:0014744 positive regulation of muscle adaptation 2.897E-3 1.663E-2
9.786E-2
5.822E-1
 1 6
35 GO:0010612 regulation of cardiac muscle adaptation 2.897E-3 1.663E-2
9.786E-2
5.822E-1
 1 6
36 GO:0031345 negative regulation of cell projection organization 3.164E-3 1.766E-2
1.039E-1
6.359E-1
 2 179
37 GO:0009566 fertilization 3.519E-3 1.912E-2
1.125E-1
7.074E-1
 2 189
38 GO:0090205 positive regulation of cholesterol metabolic process 4.342E-3 2.297E-2
1.351E-1
8.727E-1
 1 9
39 GO:0072659 protein localization to plasma membrane 4.947E-3 2.468E-2
1.452E-1
9.944E-1
 2 225
40 GO:1990778 protein localization to cell periphery 5.033E-3 2.468E-2
1.452E-1
1.000E0
 2 227
41 GO:0045665 negative regulation of neuron differentiation 5.033E-3 2.468E-2
1.452E-1
1.000E0
 2 227
42 GO:0032367 intracellular cholesterol transport 5.305E-3 2.539E-2
1.493E-1
1.000E0
 1 11
43 GO:0016358 dendrite development 5.564E-3 2.601E-2
1.530E-1
1.000E0
 2 239
44 GO:0032366 intracellular sterol transport 5.786E-3 2.643E-2
1.555E-1
1.000E0
 1 12
45 GO:0036010 protein localization to endosome 6.266E-3 2.799E-2
1.647E-1
1.000E0
 1 13
46 GO:0033235 positive regulation of protein sumoylation 7.227E-3 3.158E-2
1.858E-1
1.000E0
 1 15
47 GO:0014051 gamma-aminobutyric acid secretion 7.708E-3 3.210E-2
1.889E-1
1.000E0
 1 16
48 GO:0043270 positive regulation of ion transport 7.773E-3 3.210E-2
1.889E-1
1.000E0
 2 284
49 GO:0050768 negative regulation of neurogenesis 7.826E-3 3.210E-2
1.889E-1
1.000E0
 2 285
50 GO:0007009 plasma membrane organization 8.147E-3 3.227E-2
1.898E-1
1.000E0
 2 291
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 10 input genes in category / 68 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0034704 calcium channel complex 4.756E-4 1.784E-2
8.569E-2
 3.234E-2 2 63
2 GO:0045092 interleukin-18 receptor complex 5.246E-4 1.784E-2
8.569E-2
 3.567E-2 1 1
3 GO:0005911 cell-cell junction 1.120E-3 2.539E-2
1.220E-1
7.618E-2
 3 418
4 GO:0045323 interleukin-1 receptor complex 2.097E-3 3.166E-2
1.521E-1
1.426E-1
 1 4
5 GO:0030121 AP-1 adaptor complex 3.144E-3 3.166E-2
1.521E-1
2.138E-1
 1 6
6 GO:0034703 cation channel complex 3.634E-3 3.166E-2
1.521E-1
2.471E-1
 2 176
7 GO:0098802 plasma membrane receptor complex 3.797E-3 3.166E-2
1.521E-1
2.582E-1
 2 180
8 GO:0036056 filtration diaphragm 4.190E-3 3.166E-2
1.521E-1
2.849E-1
 1 8
9 GO:0036057 slit diaphragm 4.190E-3 3.166E-2
1.521E-1
2.849E-1
 1 8
10 GO:0005883 neurofilament 5.235E-3 3.556E-2
1.708E-1
3.560E-1
 1 10
11 GO:0030130 clathrin coat of trans-Golgi network vesicle 6.279E-3 3.556E-2
1.708E-1
4.270E-1
 1 12
12 GO:0030122 AP-2 adaptor complex 6.801E-3 3.556E-2
1.708E-1
4.625E-1
 1 13
13 GO:0016323 basolateral plasma membrane 6.863E-3 3.556E-2
1.708E-1
4.667E-1
 2 244
14 GO:0030128 clathrin coat of endocytic vesicle 7.322E-3 3.556E-2
1.708E-1
4.979E-1
 1 14
15 GO:0012510 trans-Golgi network transport vesicle membrane 7.844E-3 3.556E-2
1.708E-1
5.334E-1
 1 15
16 GO:0034702 ion channel complex 9.640E-3 3.592E-2
1.726E-1
6.555E-1
 2 291
17 GO:0042101 T cell receptor complex 9.926E-3 3.592E-2
1.726E-1
6.750E-1
 1 19
18 GO:0030132 clathrin coat of coated pit 9.926E-3 3.592E-2
1.726E-1
6.750E-1
 1 19
19 GO:0097228 sperm principal piece 1.200E-2 3.592E-2
1.726E-1
8.163E-1
 1 23
20 GO:1902495 transmembrane transporter complex 1.206E-2 3.592E-2
1.726E-1
8.198E-1
 2 327
21 GO:1990351 transporter complex 1.248E-2 3.592E-2
1.726E-1
8.487E-1
 2 333
22 GO:0043235 receptor complex 1.291E-2 3.592E-2
1.726E-1
8.782E-1
 2 339
23 GO:0030125 clathrin vesicle coat 1.304E-2 3.592E-2
1.726E-1
8.868E-1
 1 25
24 GO:0045121 membrane raft 1.321E-2 3.592E-2
1.726E-1
8.980E-1
 2 343
25 GO:0098857 membrane microdomain 1.321E-2 3.592E-2
1.726E-1
8.980E-1
 2 343
26 GO:0030140 trans-Golgi network transport vesicle 1.563E-2 3.937E-2
1.891E-1
1.000E0
 1 30
27 GO:0030131 clathrin adaptor complex 1.563E-2 3.937E-2
1.891E-1
1.000E0
 1 30
Show 22 more annotations

4: Human Phenotype [Display Chart] 4 input genes in category / 82 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 9 input genes in category / 122 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0002910 abnormal excitatory postsynaptic currents 2.167E-4 2.644E-2
1.424E-1
 2.644E-2 3 146

6: Domain [Display Chart] 10 input genes in category / 69 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF08344 TRP 2 Pfam 6.135E-13 2.117E-11 1.020E-10 4.233E-11 4 6
2 IPR013555 TRP dom InterPro 6.135E-13 2.117E-11 1.020E-10 4.233E-11 4 6
3 IPR002153 TRPC channel InterPro 1.431E-12 3.292E-11 1.586E-10 9.875E-11 4 7
4 IPR004729 TRP channel InterPro 1.348E-11 2.325E-10 1.120E-9 9.301E-10 4 11
5 IPR005821 Ion trans dom InterPro 2.655E-7 3.053E-6 1.471E-5 1.832E-5 4 114
6 PF00520 Ion trans Pfam 2.655E-7 3.053E-6 1.471E-5 1.832E-5 4 114
7 PF00023 Ank Pfam 4.462E-6 3.915E-5 1.886E-4 3.079E-4 4 231
8 1.25.40.20 - Gene3D 5.912E-6 3.915E-5 1.886E-4 4.079E-4 4 248
9 SM00248 ANK SMART 6.499E-6 3.915E-5 1.886E-4 4.484E-4 4 254
10 PS50088 ANK REPEAT PROSITE 6.704E-6 3.915E-5 1.886E-4 4.625E-4 4 256
11 PS50297 ANK REP REGION PROSITE 6.808E-6 3.915E-5 1.886E-4 4.697E-4 4 257
12 IPR020683 Ankyrin rpt-contain dom InterPro 6.808E-6 3.915E-5 1.886E-4 4.697E-4 4 257
13 IPR002110 Ankyrin rpt InterPro 7.685E-6 4.079E-5 1.966E-4 5.303E-4 4 265
14 PF12796 Ank 2 Pfam 1.685E-4 8.306E-4 4.002E-3 1.163E-2 3 215
15 IPR005461 TRPC5 channel InterPro 5.338E-4 1.938E-3 9.340E-3 3.683E-2 1 1
16 IPR005462 TRPC6 channel InterPro 5.338E-4 1.938E-3 9.340E-3 3.683E-2 1 1
17 IPR005459 TRPC3 channel InterPro 5.338E-4 1.938E-3 9.340E-3 3.683E-2 1 1
18 IPR026150 Enkur InterPro 5.338E-4 1.938E-3 9.340E-3 3.683E-2 1 1
19 IPR005460 TRPC4 channel InterPro 5.338E-4 1.938E-3 9.340E-3 3.683E-2 1 1
20 IPR027012 Enkurin dom InterPro 1.067E-3 3.347E-3 1.613E-2
7.364E-2
 1 2
21 PF13864 Enkurin Pfam 1.067E-3 3.347E-3 1.613E-2
7.364E-2
 1 2
22 PS51665 ENKURIN PROSITE 1.067E-3 3.347E-3 1.613E-2
7.364E-2
 1 2
23 SM00546 CUE SMART 3.731E-3 1.119E-2
5.393E-2
2.574E-1
 1 7
24 PF02845 CUE Pfam 4.263E-3 1.226E-2
5.906E-2
2.941E-1
 1 8
25 PS51140 CUE PROSITE 5.326E-3 1.413E-2
6.811E-2
3.675E-1
 1 10
26 IPR003892 CUE InterPro 5.326E-3 1.413E-2
6.811E-2
3.675E-1
 1 10
27 SM00744 RINGv SMART 9.039E-3 2.227E-2
1.073E-1
6.237E-1
 1 17
28 IPR011016 Znf RING-CH InterPro 9.039E-3 2.227E-2
1.073E-1
6.237E-1
 1 17
29 PF00640 PID Pfam 1.485E-2 3.227E-2
1.555E-1
1.000E0
 1 28
30 PF00617 RasGEF Pfam 1.590E-2 3.227E-2
1.555E-1
1.000E0
 1 30
31 IPR001895 RASGEF cat dom InterPro 1.590E-2 3.227E-2
1.555E-1
1.000E0
 1 30
32 SM00147 RasGEF SMART 1.590E-2 3.227E-2
1.555E-1
1.000E0
 1 30
33 1.10.840.10 - Gene3D 1.590E-2 3.227E-2
1.555E-1
1.000E0
 1 30
34 IPR023578 Ras GEF dom InterPro 1.590E-2 3.227E-2
1.555E-1
1.000E0
 1 30
35 PS01179 PID PROSITE 1.695E-2 3.342E-2
1.611E-1
1.000E0
 1 32
36 2.30.29.30 - Gene3D 1.750E-2 3.354E-2
1.616E-1
1.000E0
 2 391
37 IPR011993 PH dom-like InterPro 2.066E-2 3.835E-2
1.848E-1
1.000E0
 2 427
38 SM00462 PTB SMART 2.115E-2 3.835E-2
1.848E-1
1.000E0
 1 40
39 IPR006020 PTB/PI dom InterPro 2.168E-2 3.835E-2
1.848E-1
1.000E0
 1 41
40 PF13639 zf-RING 2 Pfam 2.742E-2 4.730E-2
2.279E-1
1.000E0
 1 52
Show 35 more annotations

7: Pathway [Display Chart] 7 input genes in category / 35 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1270317 Role of second messengers in netrin-1 signaling BioSystems: REACTOME 7.337E-12 2.568E-10 1.065E-9 2.568E-10 4 10
2 1269954 TRP channels BioSystems: REACTOME 4.407E-10 7.712E-9 3.198E-8 1.542E-8 4 25
3 1270314 Netrin-1 signaling BioSystems: REACTOME 3.887E-9 4.534E-8 1.880E-7 1.360E-7 4 42
4 1269953 Stimuli-sensing channels BioSystems: REACTOME 1.578E-7 1.380E-6 5.724E-6 5.522E-6 4 104
5 83065 Axon guidance BioSystems: KEGG 1.278E-6 8.943E-6 3.708E-5 4.471E-5 4 175
6 1269950 Ion channel transport BioSystems: REACTOME 2.596E-6 1.515E-5 6.281E-5 9.087E-5 4 209
7 P00004 Alzheimer disease-presenilin pathway PantherDB 2.482E-5 1.241E-4 5.145E-4 8.686E-4 3 113
8 1269346 Elevation of cytosolic Ca2+ levels BioSystems: REACTOME 3.671E-5 1.606E-4 6.659E-4 1.285E-3 2 17
9 1269363 Effects of PIP2 hydrolysis BioSystems: REACTOME 9.448E-5 3.674E-4 1.524E-3 3.307E-3 2 27
10 1269345 Platelet calcium homeostasis BioSystems: REACTOME 1.250E-4 4.376E-4 1.815E-3 4.376E-3 2 31
11 1269341 Platelet homeostasis BioSystems: REACTOME 1.084E-3 3.448E-3 1.430E-2 3.792E-2 2 91
12 1269578 G alpha (q) signalling events BioSystems: REACTOME 4.722E-3 1.377E-2
5.711E-2
1.653E-1
 2 192
13 1269350 Platelet activation, signaling and aggregation BioSystems: REACTOME 9.958E-3 2.681E-2
1.112E-1
3.485E-1
 2 282
14 1270008 LDL-mediated lipid transport BioSystems: REACTOME 1.342E-2 3.220E-2
1.335E-1
4.697E-1
 1 24
15 138072 Nephrin/Neph1 signaling in the kidney podocyte BioSystems: Pathway Interaction Database 1.453E-2 3.220E-2
1.335E-1
5.086E-1
 1 26
16 M11106 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages MSigDB C2 BIOCARTA (v6.0) 1.509E-2 3.220E-2
1.335E-1
5.280E-1
 1 27
17 1270006 Chylomicron-mediated lipid transport BioSystems: REACTOME 1.564E-2 3.220E-2
1.335E-1
5.474E-1
 1 28
18 137967 Trk receptor signaling mediated by PI3K and PLC-gamma BioSystems: Pathway Interaction Database 1.786E-2 3.222E-2
1.336E-1
6.250E-1
 1 32
19 M12095 Signal transduction through IL1R MSigDB C2 BIOCARTA (v6.0) 1.841E-2 3.222E-2
1.336E-1
6.444E-1
 1 33
20 138051 EPO signaling pathway BioSystems: Pathway Interaction Database 1.841E-2 3.222E-2
1.336E-1
6.444E-1
 1 33
21 137944 IL1-mediated signaling events BioSystems: Pathway Interaction Database 1.952E-2 3.253E-2
1.349E-1
6.831E-1
 1 35
22 M984 Toll-Like Receptor Pathway MSigDB C2 BIOCARTA (v6.0) 2.062E-2 3.281E-2
1.361E-1
7.218E-1
 1 37
23 1269592 Gastrin-CREB signalling pathway via PKC and MAPK BioSystems: REACTOME 2.386E-2 3.631E-2
1.506E-1
8.351E-1
 2 446
24 1269320 Interleukin-1 signaling BioSystems: REACTOME 2.558E-2 3.731E-2
1.547E-1
8.955E-1
 1 46
25 P00054 Toll receptor signaling pathway PantherDB 2.778E-2 3.890E-2
1.613E-1
9.724E-1
 1 50
26 137958 Endothelins BioSystems: Pathway Interaction Database 2.943E-2 3.962E-2
1.643E-1
1.000E0
 1 53
Show 21 more annotations

8: Pubmed [Display Chart] 10 input genes in category / 806 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 12736151 Enhanced capacitative calcium entry and TRPC channel gene expression in human LES smooth muscle. Pubmed 1.184E-14 2.386E-12 1.735E-11 9.546E-12 4 5
2 12857742 Formation of novel TRPC channels by complex subunit interactions in embryonic brain. Pubmed 1.184E-14 2.386E-12 1.735E-11 9.546E-12 4 5
3 11390792 Calcium Channels Formed by Mammalian Trp Homologues. Pubmed 1.184E-14 2.386E-12 1.735E-11 9.546E-12 4 5
4 8646775 trp, a novel mammalian gene family essential for agonist-activated capacitative Ca2+ entry. Pubmed 1.184E-14 2.386E-12 1.735E-11 9.546E-12 4 5
5 15336983 Functional role of TRPC proteins in vivo: lessons from TRPC-deficient mouse models. Pubmed 3.553E-14 5.727E-12 4.163E-11 2.863E-11 4 6
6 25471572 Metabolism regulates the spontaneous firing of substantia nigra pars reticulata neurons via KATP and nonselective cation channels. Pubmed 8.288E-14 8.351E-12 6.071E-11 6.680E-11 4 7
7 15757897 MxA, a member of the dynamin superfamily, interacts with the ankyrin-like repeat domain of TRPC. Pubmed 8.288E-14 8.351E-12 6.071E-11 6.680E-11 4 7
8 23233529 Mechanism of stretch-induced activation of the mechanotransducer zyxin in vascular cells. Pubmed 8.288E-14 8.351E-12 6.071E-11 6.680E-11 4 7
9 12032305 Subunit composition of mammalian transient receptor potential channels in living cells. Pubmed 1.657E-13 1.214E-11 8.829E-11 1.336E-10 4 8
10 17480026 Cellular subtype distribution and developmental regulation of TRPC channel members in the mouse dorsal root ganglion. Pubmed 1.657E-13 1.214E-11 8.829E-11 1.336E-10 4 8
11 18989690 Heterogeneous distribution of TRPC proteins in the embryonic cortex. Pubmed 1.657E-13 1.214E-11 8.829E-11 1.336E-10 4 8
12 11290752 Identification of common binding sites for calmodulin and inositol 1,4,5-trisphosphate receptors on the carboxyl termini of trp channels. Pubmed 2.983E-13 1.717E-11 1.249E-10 2.404E-10 4 9
13 14505576 Homer binds TRPC family channels and is required for gating of TRPC1 by IP3 receptors. Pubmed 2.983E-13 1.717E-11 1.249E-10 2.404E-10 4 9
14 27177420 The leak channel NALCN controls tonic firing and glycolytic sensitivity of substantia nigra pars reticulata neurons. Pubmed 2.983E-13 1.717E-11 1.249E-10 2.404E-10 4 9
15 15358862 Enhanced expression of transient receptor potential channels in idiopathic pulmonary arterial hypertension. Pubmed 1.292E-11 6.945E-10 5.049E-9 1.042E-8 3 3
16 9722956 Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3, 7, 9, and X. Pubmed 2.093E-11 1.054E-9 7.664E-9 1.687E-8 4 23
17 16382100 International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels. Pubmed 2.989E-11 1.417E-9 1.030E-8 2.409E-8 4 25
18 28636132 TRPC1- and TRPC3-dependent Ca2+ signaling in mouse cortical astrocytes affects injury-evoked astrogliosis in vivo. Pubmed 5.169E-11 2.083E-9 1.514E-8 4.166E-8 3 4
19 12356946 Molecular identification and localization of Trp homologues, putative calcium channels, in pregnant human uterus. Pubmed 5.169E-11 2.083E-9 1.514E-8 4.166E-8 3 4
20 26520460 The contribution of TRPC1, TRPC3, TRPC5 and TRPC6 to touch and hearing. Pubmed 5.169E-11 2.083E-9 1.514E-8 4.166E-8 3 4
21 19834762 A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea. Pubmed 8.489E-11 3.258E-9 2.369E-8 6.842E-8 4 32
22 18701065 TRPC3 channels are required for synaptic transmission and motor coordination. Pubmed 1.292E-10 4.734E-9 3.441E-8 1.041E-7 3 5
23 19322198 Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development. Pubmed 2.909E-10 1.020E-8 7.412E-8 2.345E-7 4 43
24 16460286 An introduction to TRP channels. Pubmed 3.350E-8 9.209E-7 6.695E-6 2.700E-5 3 26
25 12970363 N-linked protein glycosylation is a major determinant for basal TRPC3 and TRPC6 channel activity. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
26 16537542 TRPC3 and TRPC4 associate to form a redox-sensitive cation channel. Evidence for expression of native TRPC3-TRPC4 heteromeric channels in endothelial cells. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
27 22306362 Diacylglycerol-containing oleic acid induces increases in [Ca(2+)](i) via TRPC3/6 channels in human T-cells. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
28 26317356 Acute Treatment with a Novel TRPC4/C5 Channel Inhibitor Produces Antidepressant and Anxiolytic-Like Effects in Mice. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
29 17217053 Canonical transient receptor potential 5. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
30 20190513 [Mechanism of cardiac hypertrophy via diacylglycerol-sensitive TRPC channels]. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
31 23677990 Conserved gating elements in TRPC4 and TRPC5 channels. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
32 9512398 Differential distribution of TRP Ca2+ channel isoforms in mouse brain. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
33 10816590 TRP4 (CCE1) protein is part of native calcium release-activated Ca2+-like channels in adrenal cells. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
34 12531519 mRNA distribution analysis of human TRPC family in CNS and peripheral tissues. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
35 27861908 Differences in TRPC3 and TRPC6 channels assembly in mesenteric vascular smooth muscle cells in essential hypertension. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
36 22457348 Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
37 24453217 Combined TRPC3 and TRPC6 blockade by selective small-molecule or genetic deletion inhibits pathological cardiac hypertrophy. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
38 9687496 A novel capacitative calcium entry channel expressed in excitable cells. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
39 17850865 RNF24, a new TRPC interacting protein, causes the intracellular retention of TRPC. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
40 19549525 Deletion of TRPC4 and TRPC6 in mice impairs smooth muscle contraction and intestinal motility in vivo. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
41 22724068 TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
42 21980113 Balancing calcium signals through TRPC5 and TRPC6 in podocytes. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
43 19749484 Regulation of cardiac hypertrophy by the formation of G protein-coupled receptor--TRPC channel protein complex. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
44 17593972 Corticolimbic expression of TRPC4 and TRPC5 channels in the rodent brain. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
45 30038709 TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
46 28835433 Integration of TRPC6 and NADPH oxidase activation in lysophosphatidylcholine-induced TRPC5 externalization. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
47 20978238 Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
48 12766233 Store-operated Ca2+ entry in first trimester and term human placenta. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
49 18495872 Elucidation of a TRPC6-TRPC5 channel cascade that restricts endothelial cell movement. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
50 9368034 Cloning and expression of a novel mammalian homolog of Drosophila transient receptor potential (Trp) involved in calcium entry secondary to activation of receptors coupled by the Gq class of G protein. Pubmed 6.170E-8 9.209E-7 6.695E-6 4.973E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 10 input genes in category / 255 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:TRPC6 TRPC6 interactions 1.074E-13 2.738E-11 1.676E-10 2.738E-11 5 17
2 int:TRPC5 TRPC5 interactions 4.564E-13 3.880E-11 2.374E-10 1.164E-10 5 22
3 int:TRPC1 TRPC1 interactions 4.564E-13 3.880E-11 2.374E-10 1.164E-10 5 22
4 int:TRPC4 TRPC4 interactions 1.217E-10 7.761E-9 4.750E-8 3.104E-8 4 17
5 int:TRPC3 TRPC3 interactions 4.522E-10 2.306E-8 1.412E-7 1.153E-7 4 23
6 int:MX1 MX1 interactions 8.282E-9 3.520E-7 2.154E-6 2.112E-6 4 46
7 int:ITPR3 ITPR3 interactions 1.999E-8 7.281E-7 4.456E-6 5.097E-6 4 57
8 int:ITPR1 ITPR1 interactions 2.465E-8 7.858E-7 4.810E-6 6.287E-6 4 60
9 int:RNF24 RNF24 interactions 8.613E-7 2.440E-5 1.494E-4 2.196E-4 2 3
10 int:TRPC7 TRPC7 interactions 2.869E-6 7.317E-5 4.478E-4 7.317E-4 2 5
11 int:ENKUR ENKUR interactions 6.022E-6 1.280E-4 7.832E-4 1.536E-3 2 7
12 int:ORAI1 ORAI1 interactions 6.022E-6 1.280E-4 7.832E-4 1.536E-3 2 7
13 int:TRPC4AP TRPC4AP interactions 3.330E-4 6.532E-3 3.998E-2
8.491E-2
 2 49
14 int:HOMER3 HOMER3 interactions 5.683E-4 1.035E-2
6.335E-2
1.449E-1
 2 64
15 int:SLC9A3R1 SLC9A3R1 interactions 1.520E-3 2.584E-2
1.582E-1
3.876E-1
 2 105
16 int:PSD4 PSD4 interactions 1.694E-3 2.699E-2
1.652E-1
4.319E-1
 1 3
17 int:PIK3R2 PIK3R2 interactions 2.423E-3 3.426E-2
2.097E-1
6.180E-1
 2 133
18 int:BLCAP BLCAP interactions 2.822E-3 3.426E-2
2.097E-1
7.195E-1
 1 5
19 int:C6orf58 C6orf58 interactions 2.822E-3 3.426E-2
2.097E-1
7.195E-1
 1 5
20 int:TRPC2 TRPC2 interactions 2.822E-3 3.426E-2
2.097E-1
7.195E-1
 1 5
21 int:TRPM2 TRPM2 interactions 2.822E-3 3.426E-2
2.097E-1
7.195E-1
 1 5
22 int:ODAM ODAM interactions 3.385E-3 3.923E-2
2.401E-1
8.632E-1
 1 6
23 int:FAM102A FAM102A interactions 3.948E-3 4.377E-2
2.679E-1
1.000E0
 1 7
24 int:TNFRSF1A TNFRSF1A interactions 4.197E-3 4.459E-2
2.729E-1
1.000E0
 2 176
25 int:STMN3 STMN3 interactions 4.511E-3 4.461E-2
2.730E-1
1.000E0
 1 8
26 int:ITCH ITCH interactions 5.023E-3 4.461E-2
2.730E-1
1.000E0
 2 193
27 int:SH2D3A SH2D3A interactions 5.074E-3 4.461E-2
2.730E-1
1.000E0
 1 9
28 int:INTS4P2 INTS4P2 interactions 5.074E-3 4.461E-2
2.730E-1
1.000E0
 1 9
29 int:SLC8A1 SLC8A1 interactions 5.074E-3 4.461E-2
2.730E-1
1.000E0
 1 9
30 int:CAV1 CAV1 interactions 5.436E-3 4.621E-2
2.828E-1
1.000E0
 2 201
31 int:EXPH5 EXPH5 interactions 5.636E-3 4.636E-2
2.837E-1
1.000E0
 1 10
32 int:OXR1 OXR1 interactions 6.198E-3 4.939E-2
3.023E-1
1.000E0
 1 11
Show 27 more annotations

10: Cytoband [Display Chart] 10 input genes in category / 10 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1p36-p35 1p36-p35 8.653E-4 8.653E-3 2.534E-2 8.653E-3 1 3
2 11q22.1 11q22.1 4.320E-3 1.839E-2
5.386E-2
 4.320E-2 1 15
3 4q27 4q27 6.330E-3 1.839E-2
5.386E-2
6.330E-2
 1 22
4 13q13.3 13q13.3 8.623E-3 1.839E-2
5.386E-2
8.623E-2
 1 30
5 10p12.1 10p12.1 9.195E-3 1.839E-2
5.386E-2
9.195E-2
 1 32
6 17q21.32 17q21.32 1.405E-2 2.129E-2
6.236E-2
1.405E-1
 1 49
7 Xq23 Xq23 1.490E-2 2.129E-2
6.236E-2
1.490E-1
 1 52
8 20p13 20p13 2.904E-2 3.631E-2
1.063E-1
2.904E-1
 1 102
9 11p15.5 11p15.5 3.605E-2 4.005E-2
1.173E-1
3.605E-1
 1 127
Show 4 more annotations

11: Transcription Factor Binding Site [Display Chart] 6 input genes in category / 32 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 8 input genes in category / 7 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 249 Transient receptor potential cation channels|Ankyrin repeat domain containing genenames.org 3.127E-10 2.189E-9 5.676E-9 2.189E-9 4 28

13: Coexpression [Display Chart] 10 input genes in category / 653 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 17823248-Table2 Mouse Breast VanHouten07 49genes GeneSigDB 8.172E-7 5.336E-4 3.767E-3 5.336E-4 3 45
2 19658189-TableS8d Human EmbryonicStemCell Xu09 85genes GeneSigDB 5.616E-4 4.854E-2
3.427E-1
3.667E-1
 2 83
3 M2912 Genes down-regulated in skin from BALB/c mice after injection of: control versus Trypanosoma cruzi (strain G). MSigDB C7: Immunologic Signatures (v6.0) 1.348E-3 4.854E-2
3.427E-1
8.803E-1
 2 129
4 M6088 Genes up-regulated in CD4 [GeneID=920] T cells: untreated (0h) versus activated by anti-CD3 and anti-CD28 and then stimulated by TGFB1 and IL4 [GeneID=7040;3565] (48h). MSigDB C7: Immunologic Signatures (v6.0) 1.913E-3 4.854E-2
3.427E-1
1.000E0
 2 154
5 M8799 Genes down-regulated in splenocytes from Foxp3-Fusion-GFP NOD mice: T reg (FOXP3+ [GeneID=50943]) versus T conv (FOXP3- [GeneID=50943]) cells. MSigDB C7: Immunologic Signatures (v6.0) 2.191E-3 4.854E-2
3.427E-1
1.000E0
 2 165
6 M2660 Genes up-regulated in late serum response of CRL 2091 cells (foreskin fibroblasts). MSigDB C6: Oncogenic Signatures (v6.0) 2.377E-3 4.854E-2
3.427E-1
1.000E0
 2 172
7 M8452 Genes up-regulated in gamma delta T cells activated by phophoantigen BrHPP and IL2 [GeneID=3558]: 0h versus 7 days. MSigDB C7: Immunologic Signatures (v6.0) 2.921E-3 4.854E-2
3.427E-1
1.000E0
 2 191
8 M6169 Genes down-regulated in D10.G4.1 T cell line (12h): control versus treated with NMU [GeneID=10874]. MSigDB C7: Immunologic Signatures (v6.0) 2.921E-3 4.854E-2
3.427E-1
1.000E0
 2 191
9 M8606 Genes down-regulated in bone marrow-derived dendritic cells: unstimulated versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]. MSigDB C7: Immunologic Signatures (v6.0) 2.981E-3 4.854E-2
3.427E-1
1.000E0
 2 193
10 M8611 Genes down-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]. MSigDB C7: Immunologic Signatures (v6.0) 3.042E-3 4.854E-2
3.427E-1
1.000E0
 2 195
11 M5437 Genes down-regulated in comparison of mast cells versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.134E-3 4.854E-2
3.427E-1
1.000E0
 2 198
12 M4408 Genes up-regulated in comparison of unstimulated memory CD4 [GeneID=920] CD8 T cells versus stimulated CD4 [GeneID=920] CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 3.134E-3 4.854E-2
3.427E-1
1.000E0
 2 198
13 M9236 Genes down-regulated in CD8 T cells with STAT4 [GeneID=6775]: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 3.134E-3 4.854E-2
3.427E-1
1.000E0
 2 198
14 M5414 Genes down-regulated in comparison of eosinophils versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 3.134E-3 4.854E-2
3.427E-1
1.000E0
 2 198
15 M5397 Genes up-regulated in comparison of eosinophils versus mast cells. MSigDB C7: Immunologic Signatures (v6.0) 3.165E-3 4.854E-2
3.427E-1
1.000E0
 2 199
16 M3368 Genes up-regulated in comparison of Th2 cells versus natural regulatory T cell (Treg). MSigDB C7: Immunologic Signatures (v6.0) 3.165E-3 4.854E-2
3.427E-1
1.000E0
 2 199
17 M6282 Genes down-regulated in medullary thymic epithelial cells (mTEC): CD80 [GeneID=941] high versus low. MSigDB C7: Immunologic Signatures (v6.0) 3.165E-3 4.854E-2
3.427E-1
1.000E0
 2 199
18 M6292 Genes up-regulated in macrophages stimulated by IFNG [GeneID=3458]: 3h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 3.165E-3 4.854E-2
3.427E-1
1.000E0
 2 199
19 M9653 Genes down-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
20 M385 Genes up-regulated in dendritic cell wildtype LPS and anti-CD40 stimulated versus dendritic cell NIK NFkB2-KO LPS and anti-CD40 stimulated. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
21 M5024 Genes down-regulated in comparison of SP1 thymocytes versus SP2 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
22 M3084 Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
23 M9778 Genes up-regulated in resting CD8 T cells: wildtype versus MIR155 [GeneID=406947] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
24 M5404 Genes up-regulated in comparison of eosinophils versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
25 M5135 Genes down-regulated in comparison of ex vivo CD4- [GeneID=920] CD8- dendritic cells (DC) versus cultured CD4- [GeneID=920] CD8- DCs. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
26 M7157 Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with HDAC inhibitors for 12h. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
27 M6639 Genes down-regulated in bone marrow-derived macrophages at 45 min stimulation by LPS: wildtype versus IL6 [GeneID=3469] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
28 M5364 Genes down-regulated in comparison of untreated eosinophils versus eosinophils treated with PMA [PubChem=4792] at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
29 M3078 Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
30 M5093 Genes up-regulated in comparison of memory CD8 T cells treated with IL7 [GeneID=3574] versus those treated with IL4 [GeneID=3565]. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
31 M9608 Genes up-regulated in CD42 low [GeneID=100133941] cells from thymus: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
32 M3448 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from adult blood. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
33 M6415 Genes up-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
34 M4504 Genes up-regulated in comparison of naive CD4 [GeneID=920] T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
35 M4494 Genes up-regulated in comparison of naive CD8 T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
36 M3438 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
37 M3440 Genes down-regulated in comparison of intrathymic T progenitor cells (ITTP) versus CD4 [GeneID=920] thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
38 M3087 Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
39 M4478 Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus monocytes cultured for 0 days. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
40 M3076 Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy CD19 [GeneID=920] B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
41 M4672 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells versus CD8 T cells treated with leukocyte costimulatory blockade antibodies. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
42 M7469 Genes down-regulated in CD4 [GeneID=920] T cells treated with IL6 [GeneID=3569]: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
43 M6062 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (6h) versus IL4 [GeneID=3565] (6h). MSigDB C7: Immunologic Signatures (v6.0) 3.196E-3 4.854E-2
3.427E-1
1.000E0
 2 200
Show 38 more annotations

14: Coexpression Atlas [Display Chart] 10 input genes in category / 904 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 10X Human 8K PBMC CD8 T cells (IL7R, CD3D, CD3E) Subtype CD8 T cells (IL7R, CD3D, CD3E)-CD8 T-cells subclass-1 (ITGB1, ANXA1, KLRB1) Top 200 Genes 10X Human 8K PBMC CD8 T cells (IL7R, CD3D, CD3E) Subtype CD8 T cells (IL7R, CD3D, CD3E)-CD8 T-cells subclass-1 (ITGB1, ANXA1, KLRB1) Top 200 Genes 2.679E-4 3.807E-2
2.811E-1
2.421E-1
 3 293
2 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory.Slc17a7 Neuron.excitatory.Slc17a7 Subtype Neuron.excitatory.Slc17a7.Syt6,Slc24a2 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory.Slc17a7 Neuron.excitatory.Slc17a7 Subtype Neuron.excitatory.Slc17a7.Syt6,Slc24a2 Top 200 Genes BrainMap 2.760E-4 3.807E-2
2.811E-1
2.495E-1
 3 296
3 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-JUNB, CCR7, FHIT Top 200 Genes 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-JUNB, CCR7, FHIT Top 200 Genes 3.191E-4 3.807E-2
2.811E-1
2.885E-1
 3 311
4 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-LYZ, S100A8, S100A9 Top 200 Genes 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-LYZ, S100A8, S100A9 Top 200 Genes 3.631E-4 3.807E-2
2.811E-1
3.282E-1
 3 325
5 10X Human 8K PBMC CD8 T cells (IL7R, CD3D, CD3E) Subtype CD8 T cells (IL7R, CD3D, CD3E)-CD8 T-cells subclass-0 (CCR7, FHIT, JUNB) Top 200 Genes 10X Human 8K PBMC CD8 T cells (IL7R, CD3D, CD3E) Subtype CD8 T cells (IL7R, CD3D, CD3E)-CD8 T-cells subclass-0 (CCR7, FHIT, JUNB) Top 200 Genes 3.797E-4 3.807E-2
2.811E-1
3.433E-1
 3 330
6 gudmap kidney adult Mesangium Meis k2 1000 kidney adult Mesangium Meis k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.436E-4 3.807E-2
2.811E-1
4.010E-1
 3 348
7 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-ITGB1, ANXA1, KLRB1 Top 200 Genes 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-ITGB1, ANXA1, KLRB1 Top 200 Genes 4.858E-4 3.807E-2
2.811E-1
4.392E-1
 3 359
8 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-RP5-1171I10.5, GZMA, CCL5 Top 200 Genes 10X Human 8K PBMC CD4 T cells Subtype CD4 T cells-RP5-1171I10.5, GZMA, CCL5 Top 200 Genes 4.858E-4 3.807E-2
2.811E-1
4.392E-1
 3 359
9 10X Human 8K PBMC T cell Subtype T cell-LDHB LTB MALAT1 Top 200 Genes 10X Human 8K PBMC T cell Subtype T cell-LDHB LTB MALAT1 Top 200 Genes 4.898E-4 3.807E-2
2.811E-1
4.427E-1
 3 360
10 10X Human 8K PBMC CD8 T cells Subtype CD8 T cells-LYZ, S100A8, S100A9 Top 200 Genes 10X Human 8K PBMC CD8 T cells Subtype CD8 T cells-LYZ, S100A8, S100A9 Top 200 Genes 5.222E-4 3.807E-2
2.811E-1
4.721E-1
 3 368
11 10X Human 8K PBMC CD8 T cell Subtype CD8 T cell-CD8B RP11-291B21.2 S100B Top 200 Genes 10X Human 8K PBMC CD8 T cell Subtype CD8 T cell-CD8B RP11-291B21.2 S100B Top 200 Genes 5.264E-4 3.807E-2
2.811E-1
4.758E-1
 3 369
12 10X Human 8K PBMC T cell Subtype T cell-CD8B RP11-291B21.2 S100B Top 200 Genes 10X Human 8K PBMC T cell Subtype T cell-CD8B RP11-291B21.2 S100B Top 200 Genes 5.347E-4 3.807E-2
2.811E-1
4.834E-1
 3 371
13 10X Human 68K PBMC CD34+ Subtype CD34+-CD34+ c8 Top 200 Genes 10X Human 68K PBMC CD34+ Subtype CD34+-CD34+ c8 Top 200 Genes 5.475E-4 3.807E-2
2.811E-1
4.949E-1
 3 374
14 smooth muscle smooth muscle Human Protein Atlas 7.404E-4 4.781E-2
3.530E-1
6.693E-1
 2 90
15 gudmap kidney adult Mesangium Meis 500 kidney adult Mesangium Meis top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 8.161E-4 4.919E-2
3.632E-1
7.378E-1
 3 429
Show 10 more annotations

15: Computational [Display Chart] 6 input genes in category / 27 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 10 input genes in category / 229 annotations before applied cutoff / 72241 genes in category

No results to display

17: Drug [Display Chart] 10 input genes in category / 1988 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ctd:C038237 1-oleoyl-2-acetylglycerol CTD 2.522E-11 5.015E-8 4.098E-7 5.015E-8 4 15
2 CID000030243 adenosine diphosphoribose Stitch 2.489E-10 2.474E-7 2.022E-6 4.948E-7 5 93
3 CID006397184 $l^{1}-borane Stitch 2.493E-9 1.652E-6 1.350E-5 4.957E-6 4 44
4 CID000004049 methylglucamine Stitch 1.021E-8 5.073E-6 4.146E-5 2.029E-5 4 62
5 ctd:D005682 Gadolinium CTD 8.004E-8 2.984E-5 2.439E-4 1.591E-4 3 21
6 CID000104865 bosentan Stitch 9.006E-8 2.984E-5 2.439E-4 1.790E-4 4 106
7 CID000001598 2-aminoethyl diphenylborinate Stitch 1.925E-7 5.467E-5 4.468E-4 3.827E-4 4 128
8 CID000023926 lanthanum Stitch 2.456E-7 6.103E-5 4.988E-4 4.883E-4 4 136
9 CID000002531 calmidazolium chloride Stitch 4.713E-7 1.041E-4 8.507E-4 9.369E-4 4 160
10 CID000001394 AC1L1BDQ Stitch 6.442E-7 1.281E-4 1.047E-3 1.281E-3 4 173
11 ctd:D002217 Carbachol CTD 1.655E-6 2.991E-4 2.444E-3 3.290E-3 3 56
12 CID000104798 strontium Stitch 2.984E-6 4.943E-4 4.039E-3 5.931E-3 3 68
13 ctd:D001464 Barium CTD 3.547E-6 5.425E-4 4.433E-3 7.052E-3 3 72
14 ctd:C520323 1-oleoyl-2-acetoyl-sn-glycerol CTD 4.824E-6 6.850E-4 5.598E-3 9.590E-3 2 8
15 CID000005701 XeC compound Stitch 5.652E-6 7.490E-4 6.121E-3 1.124E-2 3 84
16 ctd:D013324 Strontium CTD 6.200E-6 7.704E-4 6.296E-3 1.233E-2 2 9
17 CID000104751 BAPTA Stitch 7.803E-6 9.124E-4 7.457E-3 1.551E-2 4 324
18 CID000007628 borate Stitch 8.992E-6 9.931E-4 8.116E-3 1.788E-2 3 98
19 CID000061486 GdCl3 Stitch 1.138E-5 1.191E-3 9.735E-3 2.263E-2 3 106
20 CID000003371 flufenamic acid Stitch 1.204E-5 1.197E-3 9.782E-3 2.394E-2 3 108
21 ctd:C063159 1-(2-(3-(4-methoxyphenyl)propoxy)-4-methoxyphenylethyl)-1H-imidazole CTD 1.566E-5 1.482E-3 1.211E-2 3.112E-2 2 14
22 CID003518809 Clorocruoro Hem Stitch 1.779E-5 1.607E-3 1.314E-2 3.536E-2 3 123
23 CID000104810 barium Stitch 3.094E-5 2.674E-3 2.186E-2
6.151E-2
 3 148
24 ctd:D007811 Lanthanum CTD 3.967E-5 3.272E-3 2.674E-2
7.886E-2
 2 22
25 ctd:D002118 Calcium CTD 4.126E-5 3.272E-3 2.674E-2
8.202E-2
 4 495
26 CID000086322 CP094 Stitch 4.280E-5 3.272E-3 2.674E-2
8.508E-2
 3 165
27 866 UP ikarugamycin; Up 200; 2uM; MCF7; HT HG-U133A EA Broad Institute CMAP Up 7.035E-5 4.369E-3 3.571E-2
1.399E-1
 3 195
28 4141 UP Metronidazole [443-48-1]; Up 200; 23.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.143E-5 4.369E-3 3.571E-2
1.420E-1
 3 196
29 5523 DN Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT HG-U133A Broad Institute CMAP Down 7.143E-5 4.369E-3 3.571E-2
1.420E-1
 3 196
30 7440 DN Bumetanide [28395-03-1]; Down 200; 11uM; MCF7; HT HG-U133A Broad Institute CMAP Down 7.252E-5 4.369E-3 3.571E-2
1.442E-1
 3 197
31 CID000000798 indole Stitch 7.362E-5 4.369E-3 3.571E-2
1.463E-1
 3 198
32 CID000446966 AC1L9KAY Stitch 7.456E-5 4.369E-3 3.571E-2
1.482E-1
 2 30
33 CID000023982 gadolinium Stitch 7.473E-5 4.369E-3 3.571E-2
1.486E-1
 3 199
34 267 UP genistein; Up 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Up 7.473E-5 4.369E-3 3.571E-2
1.486E-1
 3 199
35 ctd:C076944 salvianolic acid B CTD 1.019E-4 5.625E-3 4.597E-2
2.025E-1
 2 35
36 ctd:D015029 Zeranol CTD 1.019E-4 5.625E-3 4.597E-2
2.025E-1
 2 35
37 CID000036523 Factrel Stitch 1.400E-4 7.525E-3
6.149E-2
2.784E-1
 3 246
38 CID003039342 ALA-10 Stitch 1.845E-4 9.407E-3
7.688E-2
3.669E-1
 2 47
39 CID004534086 KB-R7943 Stitch 1.845E-4 9.407E-3
7.688E-2
3.669E-1
 2 47
40 CID000088656 Trp-Trp Stitch 2.007E-4 9.973E-3
8.150E-2
3.989E-1
 2 49
41 CID011957395 STF Stitch 2.175E-4 1.054E-2
8.617E-2
4.323E-1
 2 51
42 ctd:C109986 2-aminoethoxydiphenyl borate CTD 3.114E-4 1.474E-2
1.205E-1
6.190E-1
 2 61
43 CID005232175 tryptophan-P-1 Stitch 3.217E-4 1.487E-2
1.215E-1
6.395E-1
 2 62
44 CID000067184 N-bromosuccinimide Stitch 3.984E-4 1.737E-2
1.419E-1
7.921E-1
 2 69
45 CID004369535 P-O-O Stitch 3.984E-4 1.737E-2
1.419E-1
7.921E-1
 2 69
46 CID000002534 NSC611747 Stitch 4.018E-4 1.737E-2
1.419E-1
7.988E-1
 3 352
47 CID000005229 AC1L1JVU Stitch 4.338E-4 1.835E-2
1.500E-1
8.624E-1
 2 72
48 CID000150911 1,3-DCG Stitch 7.380E-4 3.057E-2
2.498E-1
1.000E0
 2 94
49 CID003015046 AS-8 Stitch 8.754E-4 3.413E-2
2.789E-1
1.000E0
 1 2
50 ctd:C044295 1,2-dioctanoylglycerol CTD 8.754E-4 3.413E-2
2.789E-1
1.000E0
 1 2
Show 45 more annotations

18: Disease [Display Chart] 8 input genes in category / 122 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0024591 Malignant hyperpyrexia due to anesthesia DisGeNET Curated 2.183E-4 7.529E-3 4.054E-2 2.664E-2 2 46
2 C1561643 Chronic Kidney Diseases DisGeNET Curated 4.741E-4 7.529E-3 4.054E-2
5.784E-2
 3 340
3 cv:C1863512 Hypercholesterolemia, autosomal recessive Clinical Variations 4.937E-4 7.529E-3 4.054E-2
6.023E-2
 1 1
4 C4225158 SPINOCEREBELLAR ATAXIA 41 DisGeNET Curated 4.937E-4 7.529E-3 4.054E-2
6.023E-2
 1 1
5 OMIN:603813 HYPERCHOLESTEROLEMIA, AUTOSOMAL RECESSIVE; ARH OMIM 4.937E-4 7.529E-3 4.054E-2
6.023E-2
 1 1
6 C1858915 FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2 DisGeNET Curated 4.937E-4 7.529E-3 4.054E-2
6.023E-2
 1 1
7 OMIN:603965 FOCAL SEGMENTAL GLOMERULOSCLEROSIS 2; FSGS2 OMIM 4.937E-4 7.529E-3 4.054E-2
6.023E-2
 1 1
8 cv:C1858915 Focal segmental glomerulosclerosis 2 Clinical Variations 4.937E-4 7.529E-3 4.054E-2
6.023E-2
 1 1
9 C0152171 Idiopathic pulmonary hypertension DisGeNET BeFree 8.731E-4 1.095E-2
5.896E-2
1.065E-1
 2 92
10 C0948908 Nephrotoxic serum nephritis DisGeNET BeFree 9.871E-4 1.095E-2
5.896E-2
1.204E-1
 1 2
11 C4021729 Increased circulating very-low-density lipoprotein cholesterol DisGeNET Curated 9.871E-4 1.095E-2
5.896E-2
1.204E-1
 1 2
12 C4025000 Myocardial steatosis DisGeNET Curated 1.480E-3 1.204E-2
6.484E-2
1.806E-1
 1 3
13 C2919166 Autosomal dominant focal segmental glomerulosclerosis DisGeNET BeFree 1.480E-3 1.204E-2
6.484E-2
1.806E-1
 1 3
14 C4024924 Cerebral artery atherosclerosis DisGeNET Curated 1.480E-3 1.204E-2
6.484E-2
1.806E-1
 1 3
15 C1860488 Internal carotid artery abnormalities DisGeNET Curated 1.480E-3 1.204E-2
6.484E-2
1.806E-1
 1 3
16 C4021654 Precocious atherosclerosis DisGeNET Curated 1.973E-3 1.267E-2
6.824E-2
2.408E-1
 1 4
17 C0342881 Familial hypercholesterolemia - homozygous DisGeNET Curated 1.973E-3 1.267E-2
6.824E-2
2.408E-1
 1 4
18 C4025272 Peripheral arterial stenosis DisGeNET Curated 1.973E-3 1.267E-2
6.824E-2
2.408E-1
 1 4
19 C4280264 Premature plaque build-up in arteries DisGeNET Curated 1.973E-3 1.267E-2
6.824E-2
2.408E-1
 1 4
20 C4280569 Plaque build-up in arteries DisGeNET Curated 2.466E-3 1.368E-2
7.365E-2
3.009E-1
 1 5
21 C4280503 Premature hardening of arteries DisGeNET Curated 2.466E-3 1.368E-2
7.365E-2
3.009E-1
 1 5
22 C0018808 Heart murmur DisGeNET Curated 2.466E-3 1.368E-2
7.365E-2
3.009E-1
 1 5
23 C1848486 Premature arteriosclerosis DisGeNET Curated 2.959E-3 1.444E-2
7.776E-2
3.610E-1
 1 6
24 C4280506 Plaque build-up in arteries supplying blood to heart DisGeNET Curated 2.959E-3 1.444E-2
7.776E-2
3.610E-1
 1 6
25 C1701938 Associated Pulmonary Arterial Hypertension DisGeNET BeFree 2.959E-3 1.444E-2
7.776E-2
3.610E-1
 1 6
26 C0549399 Low density lipoprotein increased DisGeNET Curated 3.943E-3 1.850E-2
9.965E-2
4.811E-1
 1 8
27 C0221253 Xanthoma tendinosum DisGeNET Curated 4.435E-3 1.933E-2
1.041E-1
5.411E-1
 1 9
28 20090401:Caporaso Smoking behavior GWAS 4.435E-3 1.933E-2
1.041E-1
5.411E-1
 1 9
29 C0264936 Secondary pulmonary hypertension DisGeNET BeFree 5.419E-3 2.280E-2
1.228E-1
6.611E-1
 1 11
30 C0206752 Alphavirus Infections DisGeNET BeFree 6.401E-3 2.440E-2
1.314E-1
7.809E-1
 1 13
31 C0748318 Progressive renal failure DisGeNET Curated 6.401E-3 2.440E-2
1.314E-1
7.809E-1
 1 13
32 C0020544 Renal hypertension DisGeNET Curated 6.401E-3 2.440E-2
1.314E-1
7.809E-1
 1 13
33 C0002962 Angina Pectoris DisGeNET Curated 6.892E-3 2.548E-2
1.372E-1
8.408E-1
 1 14
34 C3496337 Idiopathic Nephrotic Syndrome DisGeNET Curated 7.873E-3 2.668E-2
1.437E-1
9.605E-1
 1 16
35 C0553982 Impaired left ventricular function DisGeNET Curated 7.873E-3 2.668E-2
1.437E-1
9.605E-1
 1 16
36 C0302314 Xanthoma DisGeNET Curated 7.873E-3 2.668E-2
1.437E-1
9.605E-1
 1 16
37 C1863512 HYPERCHOLESTEROLEMIA, AUTOSOMAL RECESSIVE DisGeNET Curated 8.364E-3 2.685E-2
1.446E-1
1.000E0
 1 17
38 C0020564 Hypertrophy DisGeNET Curated 8.364E-3 2.685E-2
1.446E-1
1.000E0
 1 17
39 C1533172 Infantile nystagmus syndrome DisGeNET BeFree 8.854E-3 2.700E-2
1.454E-1
1.000E0
 1 18
40 C0035067 Renal Artery Stenosis DisGeNET Curated 8.854E-3 2.700E-2
1.454E-1
1.000E0
 1 18
41 C0023212 Left-Sided Heart Failure DisGeNET Curated 9.343E-3 2.780E-2
1.497E-1
1.000E0
 1 19
42 C0595929 Serum cholesterol raised DisGeNET Curated 1.081E-2 3.068E-2
1.652E-1
1.000E0
 1 22
43 C4049702 Focal Segmental Glomerulosclerosis, Not Otherwise Specified DisGeNET BeFree 1.081E-2 3.068E-2
1.652E-1
1.000E0
 1 22
44 C0027720 Nephrosis DisGeNET Curated 1.130E-2 3.133E-2
1.687E-1
1.000E0
 1 23
45 C3266102 Steroid resistant nephrotic syndrome of childhood DisGeNET BeFree 1.179E-2 3.196E-2
1.721E-1
1.000E0
 1 24
46 C0403397 Steroid-resistant nephrotic syndrome DisGeNET Curated 1.228E-2 3.256E-2
1.754E-1
1.000E0
 1 25
47 C0155733 Atherosclerosis of aorta DisGeNET Curated 1.423E-2 3.543E-2
1.908E-1
1.000E0
 1 29
48 C0085298 Sudden Cardiac Death DisGeNET Curated 1.423E-2 3.543E-2
1.908E-1
1.000E0
 1 29
49 C0231686 Gait, Unsteady DisGeNET Curated 1.423E-2 3.543E-2
1.908E-1
1.000E0
 1 29
50 C0086445 Idiopathic Membranous Glomerulonephritis DisGeNET BeFree 1.521E-2 3.710E-2
1.998E-1
1.000E0
 1 31
Show 45 more annotations