|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
12701101
|
Loss of the Tg737 protein results in skeletal patterning defects.
|
Pubmed
|
1.205E-9
|
4.970E-6
|
4.424E-5
|
4.970E-6
|
3
|
16
|
2
|
20554972
|
Vegf regulates embryonic erythroid development through Gata1 modulation.
|
Pubmed
|
3.810E-9
|
7.855E-6
|
6.992E-5
|
1.571E-5
|
3
|
23
|
3
|
22556407
|
Heparan sulfate facilitates FGF and BMP signaling to drive mesoderm differentiation of mouse embryonic stem cells.
|
Pubmed
|
2.057E-8
|
1.211E-5
|
1.078E-4
|
8.480E-5
|
2
|
2
|
4
|
12361605
|
Interaction of FGF, Ihh/Pthlh, and BMP signaling integrates chondrocyte proliferation and hypertrophic differentiation.
|
Pubmed
|
2.057E-8
|
1.211E-5
|
1.078E-4
|
8.480E-5
|
2
|
2
|
5
|
21855631
|
Activin, BMP and FGF pathways cooperate to promote endoderm and pancreatic lineage cell differentiation from human embryonic stem cells.
|
Pubmed
|
2.057E-8
|
1.211E-5
|
1.078E-4
|
8.480E-5
|
2
|
2
|
6
|
19213939
|
Signaling hierarchy regulating human endothelial cell development.
|
Pubmed
|
2.057E-8
|
1.211E-5
|
1.078E-4
|
8.480E-5
|
2
|
2
|
7
|
15226637
|
Efficient cardiomyogenic differentiation of embryonic stem cell by fibroblast growth factor 2 and bone morphogenetic protein 2.
|
Pubmed
|
2.057E-8
|
1.211E-5
|
1.078E-4
|
8.480E-5
|
2
|
2
|
8
|
15963767
|
Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification.
|
Pubmed
|
4.473E-8
|
2.305E-5
|
2.052E-4
|
1.844E-4
|
3
|
51
|
9
|
9853822
|
Using EC and ES cell culture to study early development: recent observations on Indian hedgehog and Bmps.
|
Pubmed
|
6.170E-8
|
2.826E-5
|
2.516E-4
|
2.544E-4
|
2
|
3
|
10
|
12399320
|
Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney.
|
Pubmed
|
1.234E-7
|
4.625E-5
|
4.117E-4
|
5.087E-4
|
2
|
4
|
11
|
17556598
|
Differentiation of human embryonic stem cells in serum-free medium reveals distinct roles for bone morphogenetic protein 4, vascular endothelial growth factor, stem cell factor, and fibroblast growth factor 2 in hematopoiesis.
|
Pubmed
|
1.234E-7
|
4.625E-5
|
4.117E-4
|
5.087E-4
|
2
|
4
|
12
|
21731673
|
Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
|
Pubmed
|
1.395E-7
|
4.792E-5
|
4.265E-4
|
5.750E-4
|
4
|
378
|
13
|
12944425
|
Digit regeneration is regulated by Msx1 and BMP4 in fetal mice.
|
Pubmed
|
2.056E-7
|
5.652E-5
|
5.031E-4
|
8.478E-4
|
2
|
5
|
14
|
11714677
|
BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation.
|
Pubmed
|
2.056E-7
|
5.652E-5
|
5.031E-4
|
8.478E-4
|
2
|
5
|
15
|
16112648
|
Ascorbic acid promotes osteoclastogenesis from embryonic stem cells.
|
Pubmed
|
2.056E-7
|
5.652E-5
|
5.031E-4
|
8.478E-4
|
2
|
5
|
16
|
20843830
|
The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.
|
Pubmed
|
2.272E-7
|
5.855E-5
|
5.212E-4
|
9.367E-4
|
3
|
87
|
17
|
7589793
|
Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo.
|
Pubmed
|
3.084E-7
|
6.055E-5
|
5.390E-4
|
1.272E-3
|
2
|
6
|
18
|
19351956
|
HDAC5 is a repressor of angiogenesis and determines the angiogenic gene expression pattern of endothelial cells.
|
Pubmed
|
3.084E-7
|
6.055E-5
|
5.390E-4
|
1.272E-3
|
2
|
6
|
19
|
9244299
|
Antagonistic interactions between FGF and BMP signaling pathways: a mechanism for positioning the sites of tooth formation.
|
Pubmed
|
3.084E-7
|
6.055E-5
|
5.390E-4
|
1.272E-3
|
2
|
6
|
20
|
20224040
|
Histone deacetylase 7 controls endothelial cell growth through modulation of beta-catenin.
|
Pubmed
|
3.084E-7
|
6.055E-5
|
5.390E-4
|
1.272E-3
|
2
|
6
|
21
|
12631064
|
Evidence that bone morphogenetic protein 4 has multiple biological functions during kidney and urinary tract development.
|
Pubmed
|
3.084E-7
|
6.055E-5
|
5.390E-4
|
1.272E-3
|
2
|
6
|
22
|
17881493
|
Hedgehog induction of murine vasculogenesis is mediated by Foxf1 and Bmp4.
|
Pubmed
|
5.756E-7
|
1.052E-4
|
9.366E-4
|
2.373E-3
|
2
|
8
|
23
|
23913870
|
Prickle1 stunts limb growth through alteration of cell polarity and gene expression.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
24
|
12708796
|
In situ gene expression analysis during BMP2-induced ectopic bone formation in mice shows simultaneous endochondral and intramembranous ossification.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
25
|
9811582
|
Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
26
|
9463347
|
Integrated FGF and BMP signaling controls the progression of progenitor cell differentiation and the emergence of pattern in the embryonic anterior pituitary.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
27
|
9806931
|
Formation of Rathke's pouch requires dual induction from the diencephalon.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
28
|
20570969
|
Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
29
|
18514492
|
Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice.
|
Pubmed
|
7.400E-7
|
1.052E-4
|
9.366E-4
|
3.051E-3
|
2
|
9
|
30
|
28323137
|
Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.
|
Pubmed
|
9.250E-7
|
1.230E-4
|
1.095E-3
|
3.814E-3
|
2
|
10
|
31
|
18272352
|
Polydactyly in the mouse mutant Doublefoot involves altered Gli3 processing and is caused by a large deletion in cis to Indian hedgehog.
|
Pubmed
|
9.250E-7
|
1.230E-4
|
1.095E-3
|
3.814E-3
|
2
|
10
|
32
|
8898217
|
Msx1 controls inductive signaling in mammalian tooth morphogenesis.
|
Pubmed
|
1.130E-6
|
1.260E-4
|
1.121E-3
|
4.661E-3
|
2
|
11
|
33
|
18446812
|
Brachy-syndactyly caused by loss of Sfrp2 function.
|
Pubmed
|
1.130E-6
|
1.260E-4
|
1.121E-3
|
4.661E-3
|
2
|
11
|
34
|
21557453
|
Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling.
|
Pubmed
|
1.130E-6
|
1.260E-4
|
1.121E-3
|
4.661E-3
|
2
|
11
|
35
|
10572046
|
The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen.
|
Pubmed
|
1.130E-6
|
1.260E-4
|
1.121E-3
|
4.661E-3
|
2
|
11
|
36
|
12569124
|
Feedback control of mammalian Hedgehog signaling by the Hedgehog-binding protein, Hip1, modulates Fgf signaling during branching morphogenesis of the lung.
|
Pubmed
|
1.130E-6
|
1.260E-4
|
1.121E-3
|
4.661E-3
|
2
|
11
|
37
|
16956603
|
Fibroblast growth factor 10 is required for survival and proliferation but not differentiation of intestinal epithelial progenitor cells during murine colon development.
|
Pubmed
|
1.130E-6
|
1.260E-4
|
1.121E-3
|
4.661E-3
|
2
|
11
|
38
|
10981962
|
Hedgehog signaling regulates differentiation from double-negative to double-positive thymocyte.
|
Pubmed
|
1.356E-6
|
1.364E-4
|
1.214E-3
|
5.593E-3
|
2
|
12
|
39
|
10821773
|
Hedgehog signals regulate multiple aspects of gastrointestinal development.
|
Pubmed
|
1.356E-6
|
1.364E-4
|
1.214E-3
|
5.593E-3
|
2
|
12
|
40
|
23891934
|
Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice.
|
Pubmed
|
1.356E-6
|
1.364E-4
|
1.214E-3
|
5.593E-3
|
2
|
12
|
41
|
19879143
|
An Hh-dependent pathway in lateral plate mesoderm enables the generation of left/right asymmetry.
|
Pubmed
|
1.356E-6
|
1.364E-4
|
1.214E-3
|
5.593E-3
|
2
|
12
|
42
|
16151852
|
Apoptosis, proliferation and gene expression patterns in mouse developing tongue.
|
Pubmed
|
1.603E-6
|
1.537E-4
|
1.368E-3
|
6.609E-3
|
2
|
13
|
43
|
20847311
|
The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation.
|
Pubmed
|
1.603E-6
|
1.537E-4
|
1.368E-3
|
6.609E-3
|
2
|
13
|
44
|
12163410
|
Stomach regional specification requires Hoxa5-driven mesenchymal-epithelial signaling.
|
Pubmed
|
1.870E-6
|
1.606E-4
|
1.430E-3
|
7.710E-3
|
2
|
14
|
45
|
15537544
|
Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis.
|
Pubmed
|
1.870E-6
|
1.606E-4
|
1.430E-3
|
7.710E-3
|
2
|
14
|
46
|
17481601
|
Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton.
|
Pubmed
|
1.870E-6
|
1.606E-4
|
1.430E-3
|
7.710E-3
|
2
|
14
|
47
|
15175265
|
Signaling hierarchy downstream of retinoic acid that independently regulates vascular remodeling and endothelial cell proliferation.
|
Pubmed
|
1.870E-6
|
1.606E-4
|
1.430E-3
|
7.710E-3
|
2
|
14
|
48
|
27732085
|
FGF2 High Molecular Weight Isoforms Contribute to Osteoarthropathy in Male Mice.
|
Pubmed
|
1.870E-6
|
1.606E-4
|
1.430E-3
|
7.710E-3
|
2
|
14
|
49
|
16470614
|
Visceral endoderm function is regulated by quaking and required for vascular development.
|
Pubmed
|
2.158E-6
|
1.711E-4
|
1.523E-3
|
8.896E-3
|
2
|
15
|
50
|
22547067
|
Prevention of premature fusion of calvarial suture in GLI-Kruppel family member 3 (Gli3)-deficient mice by removing one allele of Runt-related transcription factor 2 (Runx2).
|
Pubmed
|
2.158E-6
|
1.711E-4
|
1.523E-3
|
8.896E-3
|
2
|
15
|