Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc37_9, positive side

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1: GO: Molecular Function [Display Chart] 9 input genes in category / 72 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0045125 bioactive lipid receptor activity 2.492E-11 1.794E-9 8.720E-9 1.794E-9 4 14
2 GO:0070915 lysophosphatidic acid receptor activity 3.102E-10 1.117E-8 5.428E-8 2.233E-8 3 4
3 GO:0004528 phosphodiesterase I activity 2.066E-6 4.959E-5 2.410E-4 1.488E-4 2 5
4 GO:0004551 nucleotide diphosphatase activity 4.322E-5 5.703E-4 2.772E-3 3.112E-3 2 21
5 GO:0030247 polysaccharide binding 4.753E-5 5.703E-4 2.772E-3 3.422E-3 2 22
6 GO:0001871 pattern binding 4.753E-5 5.703E-4 2.772E-3 3.422E-3 2 22
7 GO:0001965 G-protein alpha-subunit binding 1.083E-4 1.114E-3 5.416E-3 7.800E-3 2 33
8 GO:0005044 scavenger receptor activity 2.210E-4 1.989E-3 9.669E-3 1.591E-2 2 47
9 GO:0030377 urokinase plasminogen activator receptor activity 4.823E-4 3.636E-3 1.767E-2 3.472E-2 1 1
10 GO:0038024 cargo receptor activity 5.050E-4 3.636E-3 1.767E-2 3.636E-2 2 71
11 GO:0004527 exonuclease activity 6.731E-4 4.406E-3 2.141E-2 4.846E-2 2 82
12 GO:0008081 phosphoric diester hydrolase activity 9.594E-4 5.757E-3 2.798E-2
6.908E-2
 2 98
13 GO:0030165 PDZ domain binding 1.295E-3 7.172E-3 3.486E-2
9.324E-2
 2 114
14 GO:0035529 NADH pyrophosphatase activity 1.446E-3 7.306E-3 3.551E-2
1.041E-1
 1 3
15 GO:0004620 phospholipase activity 1.529E-3 7.306E-3 3.551E-2
1.101E-1
 2 124
16 GO:0016298 lipase activity 1.889E-3 7.306E-3 3.551E-2
1.360E-1
 2 138
17 GO:0035727 lysophosphatidic acid binding 1.928E-3 7.306E-3 3.551E-2
1.388E-1
 1 4
18 GO:0004771 sterol esterase activity 1.928E-3 7.306E-3 3.551E-2
1.388E-1
 1 4
19 GO:0004366 glycerol-3-phosphate O-acyltransferase activity 1.928E-3 7.306E-3 3.551E-2
1.388E-1
 1 4
20 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity 2.409E-3 8.674E-3 4.216E-2
1.735E-1
 1 5
21 GO:0052689 carboxylic ester hydrolase activity 2.622E-3 8.990E-3 4.370E-2
1.888E-1
 2 163
22 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding 3.372E-3 1.103E-2
5.364E-2
2.428E-1
 1 7
23 GO:0038036 sphingosine-1-phosphate receptor activity 3.853E-3 1.206E-2
5.862E-2
2.774E-1
 1 8
24 GO:0004518 nuclease activity 5.143E-3 1.543E-2
7.500E-2
3.703E-1
 2 230
25 GO:0042301 phosphate ion binding 6.254E-3 1.801E-2
8.755E-2
4.503E-1
 1 13
26 GO:0030246 carbohydrate binding 8.008E-3 1.865E-2
9.064E-2
5.766E-1
 2 289
27 GO:0036041 long-chain fatty acid binding 8.650E-3 1.865E-2
9.064E-2
6.228E-1
 1 18
28 GO:0047429 nucleoside-triphosphate diphosphatase activity 9.128E-3 1.865E-2
9.064E-2
6.572E-1
 1 19
29 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity 9.128E-3 1.865E-2
9.064E-2
6.572E-1
 1 19
30 GO:0071617 lysophospholipid acyltransferase activity 9.607E-3 1.865E-2
9.064E-2
6.917E-1
 1 20
31 GO:0042171 lysophosphatidic acid acyltransferase activity 9.607E-3 1.865E-2
9.064E-2
6.917E-1
 1 20
32 GO:0004622 lysophospholipase activity 1.104E-2 1.865E-2
9.064E-2
7.949E-1
 1 23
33 GO:0018734 butyrolactone hydrolase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
34 GO:0043906 Ala-tRNA(Pro) hydrolase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
35 GO:0018731 1-oxa-2-oxocycloheptane lactonase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
36 GO:0080031 methyl salicylate esterase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
37 GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
38 GO:0035460 L-ascorbate 6-phosphate lactonase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
39 GO:0034892 endosulfan lactone lactonase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
40 GO:0043907 Cys-tRNA(Pro) hydrolase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
41 GO:0010296 prenylcysteine methylesterase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
42 GO:0043905 Ser-tRNA(Thr) hydrolase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
43 GO:0043908 Ser(Gly)-tRNA(Ala) hydrolase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
44 GO:0052767 mannosyl-oligosaccharide 1,6-alpha-mannosidase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
45 GO:0052768 mannosyl-oligosaccharide 1,3-alpha-mannosidase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
46 GO:0080032 methyl jasmonate esterase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
47 GO:0018732 sulfolactone hydrolase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
48 GO:0080030 methyl indole-3-acetate esterase activity 1.247E-2 1.865E-2
9.064E-2
8.980E-1
 1 26
49 GO:0018733 3,4-dihydrocoumarin hydrolase activity 1.295E-2 1.865E-2
9.064E-2
9.324E-1
 1 27
50 GO:0051723 protein methylesterase activity 1.295E-2 1.865E-2
9.064E-2
9.324E-1
 1 27
Show 45 more annotations

2: GO: Biological Process [Display Chart] 9 input genes in category / 450 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0007204 positive regulation of cytosolic calcium ion concentration 5.939E-6 1.709E-3 1.143E-2 2.673E-3 4 280
2 GO:0051480 regulation of cytosolic calcium ion concentration 8.440E-6 1.709E-3 1.143E-2 3.798E-3 4 306
3 GO:0032060 bleb assembly 1.139E-5 1.709E-3 1.143E-2 5.127E-3 2 11
4 GO:0035025 positive regulation of Rho protein signal transduction 2.483E-5 1.896E-3 1.268E-2 1.117E-2 2 16
5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway 2.483E-5 1.896E-3 1.268E-2 1.117E-2 2 16
6 GO:0006874 cellular calcium ion homeostasis 2.698E-5 1.896E-3 1.268E-2 1.214E-2 4 411
7 GO:0055074 calcium ion homeostasis 3.077E-5 1.896E-3 1.268E-2 1.385E-2 4 425
8 GO:0072503 cellular divalent inorganic cation homeostasis 3.371E-5 1.896E-3 1.268E-2 1.517E-2 4 435
9 GO:0072507 divalent inorganic cation homeostasis 4.124E-5 2.062E-3 1.379E-2 1.856E-2 4 458
10 GO:0000187 activation of MAPK activity 4.757E-5 2.141E-3 1.432E-2 2.141E-2 3 157
11 GO:0007187 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger 7.629E-5 3.121E-3 2.087E-2 3.433E-2 3 184
12 GO:0007202 activation of phospholipase C activity 8.372E-5 3.140E-3 2.100E-2 3.768E-2 2 29
13 GO:0010863 positive regulation of phospholipase C activity 1.446E-4 4.812E-3 3.218E-2
6.509E-2
 2 38
14 GO:0043406 positive regulation of MAP kinase activity 1.517E-4 4.812E-3 3.218E-2
6.825E-2
 3 232
15 GO:0046579 positive regulation of Ras protein signal transduction 1.604E-4 4.812E-3 3.218E-2
7.218E-2
 2 40
16 GO:1900274 regulation of phospholipase C activity 1.770E-4 4.977E-3 3.329E-2
7.964E-2
 2 42
17 GO:0051057 positive regulation of small GTPase mediated signal transduction 2.125E-4 5.626E-3 3.762E-2
9.564E-2
 2 46
18 GO:0010518 positive regulation of phospholipase activity 3.042E-4 7.606E-3
5.087E-2
1.369E-1
 2 55
19 GO:0006650 glycerophospholipid metabolic process 3.699E-4 7.767E-3
5.194E-2
1.664E-1
 3 314
20 GO:0032147 activation of protein kinase activity 3.768E-4 7.767E-3
5.194E-2
1.696E-1
 3 316
21 GO:0071902 positive regulation of protein serine/threonine kinase activity 3.946E-4 7.767E-3
5.194E-2
1.776E-1
 3 321
22 GO:0010517 regulation of phospholipase activity 4.516E-4 7.767E-3
5.194E-2
2.032E-1
 2 67
23 GO:0060193 positive regulation of lipase activity 4.652E-4 7.767E-3
5.194E-2
2.093E-1
 2 68
24 GO:0038195 urokinase plasminogen activator signaling pathway 4.833E-4 7.767E-3
5.194E-2
2.175E-1
 1 1
25 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate 4.833E-4 7.767E-3
5.194E-2
2.175E-1
 1 1
26 GO:1904566 cellular response to 1-oleoyl-sn-glycerol 3-phosphate 4.833E-4 7.767E-3
5.194E-2
2.175E-1
 1 1
27 GO:1903141 negative regulation of establishment of endothelial barrier 4.833E-4 7.767E-3
5.194E-2
2.175E-1
 1 1
28 GO:1901551 negative regulation of endothelial cell development 4.833E-4 7.767E-3
5.194E-2
2.175E-1
 1 1
29 GO:0043405 regulation of MAP kinase activity 5.341E-4 8.261E-3
5.525E-2
2.404E-1
 3 356
30 GO:0007193 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway 5.507E-4 8.261E-3
5.525E-2
2.478E-1
 2 74
31 GO:0031346 positive regulation of cell projection organization 5.838E-4 8.474E-3
5.667E-2
2.627E-1
 3 367
32 GO:0060191 regulation of lipase activity 7.603E-4 1.069E-2
7.150E-2
3.421E-1
 2 87
33 GO:0046486 glycerolipid metabolic process 7.891E-4 1.076E-2
7.196E-2
3.551E-1
 3 407
34 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 8.868E-4 1.119E-2
7.480E-2
3.991E-1
 2 94
35 GO:0048709 oligodendrocyte differentiation 8.868E-4 1.119E-2
7.480E-2
3.991E-1
 2 94
36 GO:0006644 phospholipid metabolic process 8.948E-4 1.119E-2
7.480E-2
4.027E-1
 3 425
37 GO:0050769 positive regulation of neurogenesis 1.161E-3 1.412E-2
9.446E-2
5.226E-1
 3 465
38 GO:0035023 regulation of Rho protein signal transduction 1.323E-3 1.567E-2
1.048E-1
5.953E-1
 2 115
39 GO:0045860 positive regulation of protein kinase activity 1.399E-3 1.591E-2
1.064E-1
6.297E-1
 3 496
40 GO:0030505 inorganic diphosphate transport 1.449E-3 1.591E-2
1.064E-1
6.521E-1
 1 3
41 GO:0071673 positive regulation of smooth muscle cell chemotaxis 1.449E-3 1.591E-2
1.064E-1
6.521E-1
 1 3
42 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway 2.414E-3 2.445E-2
1.635E-1
1.000E0
 1 5
43 GO:0071671 regulation of smooth muscle cell chemotaxis 2.414E-3 2.445E-2
1.635E-1
1.000E0
 1 5
44 GO:0006771 riboflavin metabolic process 2.414E-3 2.445E-2
1.635E-1
1.000E0
 1 5
45 GO:0007188 adenylate cyclase-modulating G protein-coupled receptor signaling pathway 2.445E-3 2.445E-2
1.635E-1
1.000E0
 2 157
46 GO:0007266 Rho protein signal transduction 2.601E-3 2.544E-2
1.702E-1
1.000E0
 2 162
47 GO:0042726 flavin-containing compound metabolic process 2.897E-3 2.773E-2
1.855E-1
1.000E0
 1 6
48 GO:0046434 organophosphate catabolic process 3.061E-3 2.815E-2
1.883E-1
1.000E0
 2 176
49 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 3.304E-3 2.815E-2
1.883E-1
1.000E0
 2 183
50 GO:0045602 negative regulation of endothelial cell differentiation 3.379E-3 2.815E-2
1.883E-1
1.000E0
 1 7
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 9 input genes in category / 18 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0071438 invadopodium membrane 2.830E-3 3.900E-2
1.363E-1
5.094E-2
 1 6
2 GO:0071437 invadopodium 5.653E-3 3.900E-2
1.363E-1
1.018E-1
 1 12
3 GO:0030139 endocytic vesicle 6.500E-3 3.900E-2
1.363E-1
1.170E-1
 2 265

4: Human Phenotype [Display Chart] 1 input genes in category / 213 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0025477 Periarticular calcification 2.124E-4 2.586E-2
1.536E-1
 4.525E-2 1 1
2 HP:0004940 Generalized arterial calcification 4.249E-4 2.586E-2
1.536E-1
9.050E-2
 1 2
3 HP:0008732 Renal hypophosphatemia 4.249E-4 2.586E-2
1.536E-1
9.050E-2
 1 2
4 HP:0006463 Rickets of the lower limbs 6.373E-4 2.586E-2
1.536E-1
1.358E-1
 1 3
5 HP:0005096 Distal femoral bowing 6.373E-4 2.586E-2
1.536E-1
1.358E-1
 1 3
6 HP:0004576 Sclerotic vertebral endplates 8.498E-4 2.586E-2
1.536E-1
1.810E-1
 1 4
7 HP:0030757 Tooth abscess 8.498E-4 2.586E-2
1.536E-1
1.810E-1
 1 4
8 HP:0001717 Coronary artery calcification 1.275E-3 2.785E-2
1.654E-1
2.715E-1
 1 6
9 HP:0012052 Low serum calcitriol 1.275E-3 2.785E-2
1.654E-1
2.715E-1
 1 6
10 HP:0010639 Elevated alkaline phosphatase of bone origin 1.487E-3 2.785E-2
1.654E-1
3.168E-1
 1 7
11 HP:0100686 Enthesitis 1.487E-3 2.785E-2
1.654E-1
3.168E-1
 1 7
12 HP:0003020 Enlargement of the wrists 1.700E-3 2.785E-2
1.654E-1
3.620E-1
 1 8
13 HP:0011510 Drusen 1.700E-3 2.785E-2
1.654E-1
3.620E-1
 1 8
14 HP:0012508 Metamorphopsia 2.124E-3 2.951E-2
1.753E-1
4.525E-1
 1 10
15 HP:0010679 Elevated tissue non-specific alkaline phosphatase 2.549E-3 2.951E-2
1.753E-1
5.430E-1
 1 12
16 HP:0025114 Hypergranulosis 2.549E-3 2.951E-2
1.753E-1
5.430E-1
 1 12
17 HP:0005294 Arterial dissection 2.549E-3 2.951E-2
1.753E-1
5.430E-1
 1 12
18 HP:0100781 Abnormality of the sacroiliac joint 2.762E-3 2.951E-2
1.753E-1
5.883E-1
 1 13
19 HP:0004943 Accelerated atherosclerosis 2.974E-3 2.951E-2
1.753E-1
6.335E-1
 1 14
20 HP:0000117 Renal phosphate wasting 2.974E-3 2.951E-2
1.753E-1
6.335E-1
 1 14
21 HP:0005195 Polyarticular arthropathy 3.187E-3 2.951E-2
1.753E-1
6.788E-1
 1 15
22 HP:0005181 Premature coronary artery atherosclerosis 3.187E-3 2.951E-2
1.753E-1
6.788E-1
 1 15
23 HP:0005764 Polyarticular arthritis 3.187E-3 2.951E-2
1.753E-1
6.788E-1
 1 15
24 HP:0100036 Pseudo-fractures 3.612E-3 2.959E-2
1.758E-1
7.693E-1
 1 17
25 HP:0001723 Restrictive cardiomyopathy 3.612E-3 2.959E-2
1.758E-1
7.693E-1
 1 17
26 HP:0004912 Hypophosphatemic rickets 3.612E-3 2.959E-2
1.758E-1
7.693E-1
 1 17
27 HP:0012337 Abnormal homeostasis 4.249E-3 3.121E-2
1.854E-1
9.050E-1
 1 20
28 HP:0012338 Abnormal energy expenditure 4.249E-3 3.121E-2
1.854E-1
9.050E-1
 1 20
29 HP:0012340 Decreased resting energy expenditure 4.249E-3 3.121E-2
1.854E-1
9.050E-1
 1 20
30 HP:0001065 Striae distensae 4.886E-3 3.281E-2
1.949E-1
1.000E0
 1 23
31 HP:0004417 Intermittent claudication 4.886E-3 3.281E-2
1.949E-1
1.000E0
 1 23
32 HP:0003761 Calcinosis 5.099E-3 3.281E-2
1.949E-1
1.000E0
 1 24
33 HP:0001056 Milia 5.736E-3 3.281E-2
1.949E-1
1.000E0
 1 27
34 HP:0100559 Lower limb asymmetry 5.949E-3 3.281E-2
1.949E-1
1.000E0
 1 28
35 HP:0003207 Arterial calcification 5.949E-3 3.281E-2
1.949E-1
1.000E0
 1 28
36 HP:0003416 Spinal canal stenosis 6.161E-3 3.281E-2
1.949E-1
1.000E0
 1 29
37 HP:0100685 Abnormal Sharpey fiber morphology 6.161E-3 3.281E-2
1.949E-1
1.000E0
 1 29
38 HP:0005106 Abnormality of the vertebral endplates 6.161E-3 3.281E-2
1.949E-1
1.000E0
 1 29
39 HP:0100671 Abnormal trabecular bone morphology 6.161E-3 3.281E-2
1.949E-1
1.000E0
 1 29
40 HP:0004950 Peripheral arterial stenosis 6.161E-3 3.281E-2
1.949E-1
1.000E0
 1 29
41 HP:0004934 Vascular calcification 6.586E-3 3.421E-2
2.033E-1
1.000E0
 1 31
42 HP:0001681 Angina pectoris 7.011E-3 3.555E-2
2.112E-1
1.000E0
 1 33
43 HP:0000127 Renal salt wasting 7.648E-3 3.602E-2
2.140E-1
1.000E0
 1 36
44 HP:0002584 Intestinal bleeding 7.648E-3 3.602E-2
2.140E-1
1.000E0
 1 36
45 HP:0025092 Epidermal acanthosis 7.861E-3 3.602E-2
2.140E-1
1.000E0
 1 37
46 HP:0002970 Genu varum 8.286E-3 3.602E-2
2.140E-1
1.000E0
 1 39
47 HP:0007392 Excessive wrinkled skin 8.286E-3 3.602E-2
2.140E-1
1.000E0
 1 39
48 HP:0011915 Cardiovascular calcification 8.286E-3 3.602E-2
2.140E-1
1.000E0
 1 39
49 HP:0002982 Tibial bowing 8.286E-3 3.602E-2
2.140E-1
1.000E0
 1 39
50 HP:0100679 Lack of skin elasticity 8.923E-3 3.801E-2
2.258E-1
1.000E0
 1 42
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 9 input genes in category / 380 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 9 input genes in category / 46 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR004065 LPA rcpt InterPro 7.665E-11 3.526E-9 1.557E-8 3.526E-9 3 3
2 SM01381 7TM GPCR Srsx SMART 1.490E-7 3.427E-6 1.514E-5 6.855E-6 4 112
3 IPR020436 Somatomedin B chordata InterPro 2.050E-6 1.571E-5 6.939E-5 9.429E-5 2 5
4 SM00892 Endonuclease NS SMART 3.074E-6 1.571E-5 6.939E-5 1.414E-4 2 6
5 PF01223 Endonuclease NS Pfam 3.074E-6 1.571E-5 6.939E-5 1.414E-4 2 6
6 SM00477 NUC SMART 3.074E-6 1.571E-5 6.939E-5 1.414E-4 2 6
7 IPR020821 Extracellular endonuc su A InterPro 3.074E-6 1.571E-5 6.939E-5 1.414E-4 2 6
8 3.40.570.10 - Gene3D 3.074E-6 1.571E-5 6.939E-5 1.414E-4 2 6
9 IPR001604 DNA/RNA non-sp Endonuclease InterPro 3.074E-6 1.571E-5 6.939E-5 1.414E-4 2 6
10 IPR024873 E-NPP InterPro 4.303E-6 1.979E-5 8.741E-5 1.979E-4 2 7
11 PF01033 Somatomedin B Pfam 5.735E-6 2.398E-5 1.059E-4 2.638E-4 2 8
12 SM00201 SO SMART 7.372E-6 2.493E-5 1.101E-4 3.391E-4 2 9
13 PS00524 SMB 1 PROSITE 9.213E-6 2.493E-5 1.101E-4 4.238E-4 2 10
14 IPR002591 Phosphodiest/P Trfase InterPro 9.213E-6 2.493E-5 1.101E-4 4.238E-4 2 10
15 PS50958 SMB 2 PROSITE 9.213E-6 2.493E-5 1.101E-4 4.238E-4 2 10
16 PF01663 Phosphodiest Pfam 9.213E-6 2.493E-5 1.101E-4 4.238E-4 2 10
17 IPR001212 Somatomedin B dom InterPro 9.213E-6 2.493E-5 1.101E-4 4.238E-4 2 10
18 IPR017850 Alkaline phosphatase core InterPro 9.470E-5 2.178E-4 9.620E-4 4.356E-3 2 31
19 IPR017849 Alkaline Pase-like a/b/a InterPro 9.470E-5 2.178E-4 9.620E-4 4.356E-3 2 31
20 3.40.720.10 - Gene3D 9.470E-5 2.178E-4 9.620E-4 4.356E-3 2 31
21 IPR005385 LPA rcpt EDG7 InterPro 4.804E-4 8.499E-4 3.754E-3 2.210E-2 1 1
22 IPR004062 EDG3 rcpt InterPro 4.804E-4 8.499E-4 3.754E-3 2.210E-2 1 1
23 IPR029881 ENPP2 InterPro 4.804E-4 8.499E-4 3.754E-3 2.210E-2 1 1
24 IPR033084 U-PAR InterPro 4.804E-4 8.499E-4 3.754E-3 2.210E-2 1 1
25 IPR029890 ENPP1 InterPro 4.804E-4 8.499E-4 3.754E-3 2.210E-2 1 1
26 IPR004066 LPA rcpt EDG4 InterPro 4.804E-4 8.499E-4 3.754E-3 2.210E-2 1 1
27 IPR002277 LPA rcpt EDG2 InterPro 9.606E-4 1.578E-3 6.970E-3 4.419E-2 1 2
28 IPR000987 EDG1 rcpt InterPro 9.606E-4 1.578E-3 6.970E-3 4.419E-2 1 2
29 IPR033140 Lipase GDXG put SER AS InterPro 1.920E-3 2.849E-3 1.259E-2
8.833E-2
 1 4
30 IPR017157 Arylacetamide deacetylase InterPro 1.920E-3 2.849E-3 1.259E-2
8.833E-2
 1 4
31 IPR002168 Lipase GDXG HIS AS InterPro 1.920E-3 2.849E-3 1.259E-2
8.833E-2
 1 4
32 IPR004061 S1P rcpt InterPro 2.400E-3 3.450E-3 1.524E-2
1.104E-1
 1 5
33 PS01173 LIPASE GDXG HIS PROSITE 2.879E-3 3.784E-3 1.671E-2
1.324E-1
 1 6
34 IPR018363 CD59 antigen CS InterPro 2.879E-3 3.784E-3 1.671E-2
1.324E-1
 1 6
35 PS01174 LIPASE GDXG SER PROSITE 2.879E-3 3.784E-3 1.671E-2
1.324E-1
 1 6
36 IPR013094 AB hydrolase 3 InterPro 3.358E-3 4.175E-3 1.844E-2
1.545E-1
 1 7
37 PF07859 Abhydrolase 3 Pfam 3.358E-3 4.175E-3 1.844E-2
1.545E-1
 1 7
38 SM00134 LU SMART 7.662E-3 9.037E-3 3.991E-2
3.524E-1
 1 16
39 PF01553 Acyltransferase Pfam 7.662E-3 9.037E-3 3.991E-2
3.524E-1
 1 16
40 IPR002123 Plipid/glycerol acylTrfase InterPro 8.139E-3 9.131E-3 4.033E-2
3.744E-1
 1 17
41 SM00563 PlsC SMART 8.139E-3 9.131E-3 4.033E-2
3.744E-1
 1 17
42 PF00021 UPAR LY6 Pfam 9.569E-3 1.048E-2 4.629E-2
4.402E-1
 1 20
43 PS00983 LY6 UPAR PROSITE 1.052E-2 1.100E-2 4.858E-2
4.840E-1
 1 22
44 IPR016054 LY6 UPA recep-like InterPro 1.052E-2 1.100E-2 4.858E-2
4.840E-1
 1 22
Show 39 more annotations

7: Pathway [Display Chart] 9 input genes in category / 60 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269567 Lysosphingolipid and LPA receptors BioSystems: REACTOME 1.256E-10 7.539E-9 3.528E-8 7.539E-9 4 14
2 M17668 Rho-Selective Guanine Exchange Factor AKAP13 Mediates Stress Fiber Formation MSigDB C2 BIOCARTA (v6.0) 5.728E-8 1.719E-6 8.043E-6 3.437E-6 3 12
3 137928 LPA receptor mediated events BioSystems: Pathway Interaction Database 1.116E-5 2.002E-4 9.367E-4 6.694E-4 3 65
4 1269576 G alpha (i) signalling events BioSystems: REACTOME 1.652E-5 2.002E-4 9.367E-4 9.911E-4 4 243
5 PW:0000228 G protein signaling via Galphai family Pathway Ontology 1.668E-5 2.002E-4 9.367E-4 1.001E-3 2 9
6 83053 Neuroactive ligand-receptor interaction BioSystems: KEGG 2.806E-5 2.806E-4 1.313E-3 1.684E-3 4 278
7 PW:0000229 G protein signaling via Galphaq family Pathway Ontology 4.208E-5 3.607E-4 1.688E-3 2.525E-3 2 14
8 1269545 Class A/1 (Rhodopsin-like receptors) BioSystems: REACTOME 4.994E-5 3.745E-4 1.753E-3 2.996E-3 4 322
9 1270149 Vitamin B5 (pantothenate) metabolism BioSystems: REACTOME 6.282E-5 4.188E-4 1.960E-3 3.769E-3 2 17
10 1311074 Phospholipase D signaling pathway BioSystems: KEGG 1.260E-4 7.561E-4 3.539E-3 7.561E-3 3 146
11 1269544 GPCR ligand binding BioSystems: REACTOME 1.916E-4 1.045E-3 4.892E-3 1.150E-2 4 455
12 1269578 G alpha (q) signalling events BioSystems: REACTOME 2.833E-4 1.416E-3 6.628E-3 1.700E-2 3 192
13 868086 Rap1 signaling pathway BioSystems: KEGG 3.687E-4 1.702E-3 7.964E-3 2.212E-2 3 210
14 692234 PI3K-Akt signaling pathway BioSystems: KEGG 1.526E-3 6.540E-3 3.061E-2
9.156E-2
 3 342
15 83105 Pathways in cancer BioSystems: KEGG 2.308E-3 9.234E-3 4.321E-2
1.385E-1
 3 395
16 1269592 Gastrin-CREB signalling pathway via PKC and MAPK BioSystems: REACTOME 3.264E-3 1.140E-2
5.335E-2
1.958E-1
 3 446
17 1270145 Metabolism of water-soluble vitamins and cofactors BioSystems: REACTOME 3.438E-3 1.140E-2
5.335E-2
2.063E-1
 2 125
18 SMP00070 Riboflavin Metabolism SMPDB 3.610E-3 1.140E-2
5.335E-2
2.166E-1
 1 5
19 SMP00027 Pantothenate and CoA Biosynthesis SMPDB 3.610E-3 1.140E-2
5.335E-2
2.166E-1
 1 5
20 1268713 Attachment of GPI anchor to uPAR BioSystems: REACTOME 5.050E-3 1.443E-2
6.753E-2
3.030E-1
 1 7
21 1270148 Vitamin B2 (riboflavin) metabolism BioSystems: REACTOME 5.050E-3 1.443E-2
6.753E-2
3.030E-1
 1 7
22 83012 Riboflavin metabolism BioSystems: KEGG 5.770E-3 1.574E-2
7.365E-2
3.462E-1
 1 8
23 1270144 Metabolism of vitamins and cofactors BioSystems: REACTOME 6.776E-3 1.768E-2
8.272E-2
4.065E-1
 2 177
24 SMP00048 Nicotinate and Nicotinamide Metabolism SMPDB 8.644E-3 2.161E-2
1.011E-1
5.186E-1
 1 12
25 1269372 Dissolution of Fibrin Clot BioSystems: REACTOME 9.361E-3 2.247E-2
1.051E-1
5.617E-1
 1 13
26 138038 Arf6 downstream pathway BioSystems: Pathway Interaction Database 1.079E-2 2.491E-2
1.166E-1
6.477E-1
 1 15
27 413384 Triacylglycerol biosynthesis BioSystems: KEGG 1.223E-2 2.620E-2
1.226E-1
7.336E-1
 1 17
28 P00050 Plasminogen activating cascade PantherDB 1.223E-2 2.620E-2
1.226E-1
7.336E-1
 1 17
29 83015 Pantothenate and CoA biosynthesis BioSystems: KEGG 1.294E-2 2.677E-2
1.253E-1
7.765E-1
 1 18
30 142255 CDP-diacylglycerol biosynthesis BioSystems: BIOCYC 1.366E-2 2.731E-2
1.278E-1
8.193E-1
 1 19
31 137931 Sphingosine 1-phosphate (S1P) pathway BioSystems: Pathway Interaction Database 1.508E-2 2.919E-2
1.366E-1
9.050E-1
 1 21
32 1270008 LDL-mediated lipid transport BioSystems: REACTOME 1.722E-2 3.229E-2
1.511E-1
1.000E0
 1 24
33 142242 triacylglycerol biosynthesis BioSystems: BIOCYC 1.793E-2 3.261E-2
1.526E-1
1.000E0
 1 25
34 PW:0000143 insulin signaling Pathway Ontology 1.936E-2 3.416E-2
1.599E-1
1.000E0
 1 27
35 138063 S1P3 pathway BioSystems: Pathway Interaction Database 2.007E-2 3.440E-2
1.610E-1
1.000E0
 1 28
36 83014 Nicotinate and nicotinamide metabolism BioSystems: KEGG 2.078E-2 3.463E-2
1.620E-1
1.000E0
 1 29
37 169349 Validated transcriptional targets of AP1 family members Fra1 and Fra2 BioSystems: Pathway Interaction Database 2.432E-2 3.840E-2
1.797E-1
1.000E0
 1 34
38 1270055 Synthesis of PA BioSystems: REACTOME 2.432E-2 3.840E-2
1.797E-1
1.000E0
 1 34
39 82974 Starch and sucrose metabolism BioSystems: KEGG 2.573E-2 3.959E-2
1.853E-1
1.000E0
 1 36
40 P00011 Blood coagulation PantherDB 2.856E-2 4.283E-2
2.005E-1
1.000E0
 1 40
41 82990 Ether lipid metabolism BioSystems: KEGG 3.207E-2 4.694E-2
2.197E-1
1.000E0
 1 45
42 137989 FGF signaling pathway BioSystems: Pathway Interaction Database 3.348E-2 4.769E-2
2.232E-1
1.000E0
 1 47
43 137945 amb2 Integrin signaling BioSystems: Pathway Interaction Database 3.418E-2 4.769E-2
2.232E-1
1.000E0
 1 48
Show 38 more annotations

8: Pubmed [Display Chart] 9 input genes in category / 1587 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20458606 Stimulatory actions of lysophosphatidic acid on mouse ATDC5 chondroprogenitor cells. Pubmed 8.593E-17 1.364E-13 1.084E-12 1.364E-13 5 11
2 18924241 Expression patterns of the lysophospholipid receptor genes during mouse early development. Pubmed 2.393E-16 1.899E-13 1.509E-12 3.798E-13 5 13
3 16782887 Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Pubmed 4.973E-14 2.631E-11 2.091E-10 7.893E-11 4 7
4 16829511 Autotaxin stabilizes blood vessels and is required for embryonic vasculature by producing lysophosphatidic acid. Pubmed 9.946E-14 3.391E-11 2.695E-10 1.578E-10 4 8
5 21319224 Expression of LPP3 in Bergmann glia is required for proper cerebellar sphingosine-1-phosphate metabolism/signaling and development. Pubmed 1.068E-13 3.391E-11 2.695E-10 1.695E-10 5 39
6 22465231 Lysophosphatidic acid induces neurite branch formation through LPA3. Pubmed 2.983E-13 6.763E-11 5.375E-10 4.734E-10 4 10
7 12401212 Embryonic brain expression analysis of lysophospholipid receptor genes suggests roles for s1p(1) in neurogenesis and s1p(1-3) in angiogenesis. Pubmed 2.983E-13 6.763E-11 5.375E-10 4.734E-10 4 10
8 24602016 Lysophospholipid receptor nomenclature review: IUPHAR Review 8. Pubmed 1.938E-12 3.844E-10 3.055E-9 3.076E-9 4 15
9 23569130 Enhancement of invasion of hepatocellular carcinoma cells through lysophosphatidic acid receptor. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
10 12123830 Lysophosphatidic acid (LPA) receptors are activated differentially by biological fluids: possible role of LPA-binding proteins in activation of LPA receptors. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
11 20495828 LPA receptor expression in the central nervous system in health and following injury. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
12 18448840 Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
13 19025891 Gene expression profiles of lysophosphatidic acid-related molecules in the prostate: relevance to prostate cancer and benign hyperplasia. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
14 11093753 Lysophosphatidic acid receptors. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
15 19899077 Lysophosphatidic acid receptor activation affects the C13NJ microglia cell line proteome leading to alterations in glycolysis, motility, and cytoskeletal architecture. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
16 24829209 Lysophosphatidic acid acts as a nutrient-derived developmental cue to regulate early hematopoiesis. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
17 22015657 Lysophosphatidic acid signaling protects pulmonary vasculature from hypoxia-induced remodeling. Pubmed 9.047E-12 8.446E-10 6.712E-9 1.436E-8 3 3
18 11087877 Requirement for the lpA1 lysophosphatidic acid receptor gene in normal suckling behavior. Pubmed 3.618E-11 2.610E-9 2.074E-8 5.742E-8 3 4
19 24429286 Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity. Pubmed 3.618E-11 2.610E-9 2.074E-8 5.742E-8 3 4
20 27760754 Lysophosphatidic acid-induced vascular neointimal formation in mouse carotid arteries is mediated by the matricellular protein CCN1/Cyr61. Pubmed 3.618E-11 2.610E-9 2.074E-8 5.742E-8 3 4
21 24061591 Lysophosphatidic acid stimulates activation of focal adhesion kinase and paxillin and promotes cell motility, via LPA1-3, in human pancreatic cancer. Pubmed 3.618E-11 2.610E-9 2.074E-8 5.742E-8 3 4
22 19081821 Lysophosphatidic acid (LPA)-induced vasodilator-stimulated phosphoprotein mediates lamellipodia formation to initiate motility in PC-3 prostate cancer cells. Pubmed 3.618E-11 2.610E-9 2.074E-8 5.742E-8 3 4
23 29724718 The Autotaxin-Lysophosphatidic Acid Axis Promotes Lung Carcinogenesis. Pubmed 9.045E-11 5.981E-9 4.753E-8 1.435E-7 3 5
24 20505096 Diversity of lysophosphatidic acid receptor-mediated intracellular calcium signaling in early cortical neurogenesis. Pubmed 9.045E-11 5.981E-9 4.753E-8 1.435E-7 3 5
25 11313151 The mouse lp(A3)/Edg7 lysophosphatidic acid receptor gene: genomic structure, chromosomal localization, and expression pattern. Pubmed 1.809E-10 1.063E-8 8.449E-8 2.871E-7 3 6
26 12730698 A new phospholipid phosphatase, PRG-1, is involved in axon growth and regenerative sprouting. Pubmed 1.809E-10 1.063E-8 8.449E-8 2.871E-7 3 6
27 15755723 Physical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs). Pubmed 1.809E-10 1.063E-8 8.449E-8 2.871E-7 3 6
28 19860625 Lysophosphatidic acid receptor expression in chronic lymphocytic leukemia leads to cell survival mediated though vascular endothelial growth factor expression. Pubmed 5.063E-10 2.870E-8 2.281E-7 8.036E-7 3 8
29 16434032 Sphingosine-1-phosphate inhibits cell migration and endothelial to mesenchymal cell transformation during cardiac development. Pubmed 1.085E-9 5.936E-8 4.718E-7 1.722E-6 3 10
30 27244685 Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
31 18754873 Lysophosphatidic acid stimulates the proliferation and motility of malignant pleural mesothelioma cells through lysophosphatidic acid receptors, LPA1 and LPA2. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
32 27883026 Inhibition of lysophosphatidic acid receptors 1 and 3 attenuates atherosclerosis development in LDL-receptor deficient mice. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
33 21116120 Mutations of lysophosphatidic acid receptor genes in human osteosarcoma cells. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
34 15195086 Initiation of neuropathic pain requires lysophosphatidic acid receptor signaling. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
35 21971049 Autotaxin regulates vascular development via multiple lysophosphatidic acid (LPA) receptors in zebrafish. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
36 26327335 The significance of the altered expression of lysophosphatidic acid receptors, autotaxin and phospholipase A2 as the potential biomarkers in type 1 endometrial cancer biology. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
37 17923111 Lysophosphatidic acid regulates inflammation-related genes in human endothelial cells through LPA1 and LPA3. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
38 21900594 Lysophosphatidic acid signaling may initiate fetal hydrocephalus. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
39 20360252 Lysophosphatidic acid receptors LPA1 and LPA3 promote CXCL12-mediated smooth muscle progenitor cell recruitment in neointima formation. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
40 9804623 Recombinant human G protein-coupled lysophosphatidic acid receptors mediate intracellular calcium mobilization. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
41 19001604 Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
42 17496233 LPA2 (EDG4) mediates Rho-dependent chemotaxis with lower efficacy than LPA1 (EDG2) in breast carcinoma cells. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
43 18280050 Lysophosphatidylcholine induces neuropathic pain through an action of autotaxin to generate lysophosphatidic acid. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
44 14625558 Non-proliferative effects of lysophosphatidic acid enhance cortical growth and folding. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
45 25463482 Opposing regulation of megakaryopoiesis by LPA receptors 2 and 3 in K562 human erythroleukemia cells. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
46 10537322 Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
47 25411045 Lysophosphatidic acid and its receptors LPA1 and LPA3 mediate paclitaxel-induced neuropathic pain in mice. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
48 18703779 Lysophosphatidic acid receptors 1 and 2 play roles in regulation of vascular injury responses but not blood pressure. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
49 12215548 Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
50 26027517 The autotaxin-LPA2 GPCR axis is modulated by γ-irradiation and facilitates DNA damage repair. Pubmed 4.936E-8 1.306E-6 1.038E-5 7.833E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 9 input genes in category / 341 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:ENPP2 ENPP2 interactions 2.296E-6 7.828E-4 5.018E-3 7.828E-4 2 5
2 int:ARHGEF11 ARHGEF11 interactions 8.625E-5 1.471E-2
9.428E-2
 2.941E-2 2 28
3 int:ARHGEF12 ARHGEF12 interactions 1.686E-4 1.916E-2
1.228E-1
5.749E-2
 2 39
4 int:ITGB4 ITGB4 interactions 2.669E-4 2.275E-2
1.458E-1
9.100E-2
 2 49
5 int:LYPD3 LYPD3 interactions 1.590E-3 2.915E-2
1.869E-1
5.422E-1
 2 120
6 int:GPR137 GPR137 interactions 2.032E-3 2.915E-2
1.869E-1
6.930E-1
 1 4
7 int:CERS4 CERS4 interactions 2.032E-3 2.915E-2
1.869E-1
6.930E-1
 1 4
8 int:TEX101 TEX101 interactions 2.032E-3 2.915E-2
1.869E-1
6.930E-1
 1 4
9 int:SRPX2 SRPX2 interactions 2.032E-3 2.915E-2
1.869E-1
6.930E-1
 1 4
10 int:LPAR1 LPAR1 interactions 2.437E-3 2.915E-2
1.869E-1
8.310E-1
 2 149
11 int:S1PR3 S1PR3 interactions 2.540E-3 2.915E-2
1.869E-1
8.660E-1
 1 5
12 int:RNF121 RNF121 interactions 2.540E-3 2.915E-2
1.869E-1
8.660E-1
 1 5
13 int:LPAR3 LPAR3 interactions 2.540E-3 2.915E-2
1.869E-1
8.660E-1
 1 5
14 int:TMEM87B TMEM87B interactions 2.540E-3 2.915E-2
1.869E-1
8.660E-1
 1 5
15 int:MMP12 MMP12 interactions 3.047E-3 2.915E-2
1.869E-1
1.000E0
 1 6
16 int:TPCN1 TPCN1 interactions 3.554E-3 2.915E-2
1.869E-1
1.000E0
 1 7
17 int:TMEM161B TMEM161B interactions 3.554E-3 2.915E-2
1.869E-1
1.000E0
 1 7
18 int:ST3GAL6 ST3GAL6 interactions 3.554E-3 2.915E-2
1.869E-1
1.000E0
 1 7
19 int:MFSD12 MFSD12 interactions 3.554E-3 2.915E-2
1.869E-1
1.000E0
 1 7
20 int:UGT3A2 UGT3A2 interactions 4.061E-3 2.915E-2
1.869E-1
1.000E0
 1 8
21 int:LARGE1 LARGE1 interactions 4.061E-3 2.915E-2
1.869E-1
1.000E0
 1 8
22 int:BMP8B BMP8B interactions 4.061E-3 2.915E-2
1.869E-1
1.000E0
 1 8
23 int:ADGRL3 ADGRL3 interactions 4.061E-3 2.915E-2
1.869E-1
1.000E0
 1 8
24 int:LGALS3 LGALS3 interactions 4.467E-3 2.915E-2
1.869E-1
1.000E0
 2 203
25 int:MT-CO3 MT-CO3 interactions 4.567E-3 2.915E-2
1.869E-1
1.000E0
 1 9
26 int:TMEM38A TMEM38A interactions 4.567E-3 2.915E-2
1.869E-1
1.000E0
 1 9
27 int:LRRC3 LRRC3 interactions 4.567E-3 2.915E-2
1.869E-1
1.000E0
 1 9
28 int:TESC TESC interactions 4.567E-3 2.915E-2
1.869E-1
1.000E0
 1 9
29 int:HTR1A HTR1A interactions 5.074E-3 2.915E-2
1.869E-1
1.000E0
 1 10
30 int:FAM210B FAM210B interactions 5.074E-3 2.915E-2
1.869E-1
1.000E0
 1 10
31 int:ENPP4 ENPP4 interactions 5.074E-3 2.915E-2
1.869E-1
1.000E0
 1 10
32 int:ELOVL2 ELOVL2 interactions 5.074E-3 2.915E-2
1.869E-1
1.000E0
 1 10
33 int:EVI2A EVI2A interactions 5.074E-3 2.915E-2
1.869E-1
1.000E0
 1 10
34 int:ALG6 ALG6 interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
35 int:LPAR2 LPAR2 interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
36 int:MGAT4B MGAT4B interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
37 int:TATDN2 TATDN2 interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
38 int:NDST1 NDST1 interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
39 int:CERS5 CERS5 interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
40 int:TRMT11 TRMT11 interactions 5.580E-3 2.915E-2
1.869E-1
1.000E0
 1 11
41 int:PEX13 PEX13 interactions 6.086E-3 2.915E-2
1.869E-1
1.000E0
 1 12
42 int:MTFP1 MTFP1 interactions 6.086E-3 2.915E-2
1.869E-1
1.000E0
 1 12
43 int:SGSH SGSH interactions 6.086E-3 2.915E-2
1.869E-1
1.000E0
 1 12
44 int:ARSB ARSB interactions 6.086E-3 2.915E-2
1.869E-1
1.000E0
 1 12
45 int:GPAT3 GPAT3 interactions 6.086E-3 2.915E-2
1.869E-1
1.000E0
 1 12
46 int:MAN1A1 MAN1A1 interactions 6.086E-3 2.915E-2
1.869E-1
1.000E0
 1 12
47 int:PCYOX1L PCYOX1L interactions 6.591E-3 2.915E-2
1.869E-1
1.000E0
 1 13
48 int:CMTM4 CMTM4 interactions 6.591E-3 2.915E-2
1.869E-1
1.000E0
 1 13
49 int:EMILIN3 EMILIN3 interactions 6.591E-3 2.915E-2
1.869E-1
1.000E0
 1 13
50 int:SC5D SC5D interactions 6.591E-3 2.915E-2
1.869E-1
1.000E0
 1 13
Show 45 more annotations

10: Cytoband [Display Chart] 9 input genes in category / 9 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 9q22.1-q22.2 9q22.1-q22.2 5.193E-4 4.673E-3 1.322E-2 4.673E-3 1 2
2 8q24.1 8q24.1 1.816E-3 7.782E-3 2.201E-2 1.635E-2 1 7
3 6q22-q23 6q22-q23 2.594E-3 7.782E-3 2.201E-2 2.334E-2 1 10
4 4q21.23 4q21.23 3.630E-3 7.931E-3 2.244E-2 3.267E-2 1 14
5 3q26.31 3q26.31 4.406E-3 7.931E-3 2.244E-2 3.965E-2 1 17
6 1p22.3 1p22.3 5.699E-3 8.548E-3 2.418E-2
5.129E-2
 1 22
7 9q31.3 9q31.3 6.990E-3 8.987E-3 2.542E-2
6.291E-2
 1 27
8 19q13 19q13 8.795E-3 9.894E-3 2.799E-2
7.915E-2
 1 34
9 19p12 19p12 2.364E-2 2.364E-2
6.687E-2
2.128E-1
 1 92
Show 4 more annotations

11: Transcription Factor Binding Site [Display Chart] 6 input genes in category / 36 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 6 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 205 Lysophosphatidic acid receptors genenames.org 3.984E-10 2.390E-9 5.857E-9 2.390E-9 3 6
2 1035 Glycerol-3-phosphate acyltransferases genenames.org 1.319E-3 3.296E-3 8.075E-3 7.911E-3 1 4
3 206 Sphingosine 1-phosphate receptors genenames.org 1.648E-3 3.296E-3 8.075E-3 9.888E-3 1 5
4 46 1-acylglycerol-3-phosphate O-acyltransferases genenames.org 3.623E-3 5.434E-3 1.331E-2 2.174E-2 1 11
5 1226 LY6/PLAUR domain containing genenames.org 1.116E-2 1.339E-2 3.282E-2
6.697E-2
 1 34

13: Coexpression [Display Chart] 9 input genes in category / 1276 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M8717 Genes down-regulated in bone marrow-derived macrophages with MLL4 [GeneID=9757] knockout: control versus treated with LPS for 4h. MSigDB C7: Immunologic Signatures (v6.0) 6.213E-7 4.210E-4 3.254E-3 7.927E-4 4 197
2 M8722 Genes up-regulated in bone marrow-derived macrophages treated with LPS for 2h: heterozygous versus homozygous knockout of MLL4 [GeneID=9757]. MSigDB C7: Immunologic Signatures (v6.0) 6.599E-7 4.210E-4 3.254E-3 8.421E-4 4 200
3 12213285-table2 Human Prostate Li02 13genes GeneSigDB 7.384E-6 3.141E-3 2.428E-2 9.422E-3 2 11
4 18440302-SuppTable2 Human Lung Ma08 708genes GeneSigDB 1.795E-5 4.654E-3 3.597E-2 2.291E-2 4 460
5 17183690-Table1 Mouse StemCell Lian06 20genes GeneSigDB 1.824E-5 4.654E-3 3.597E-2 2.327E-2 2 17
6 19489030-SuppTable7 Human Prostate Chambers09 259genes GeneSigDB 4.770E-5 7.064E-3
5.460E-2
6.087E-2
 3 195
7 M5994 Genes up-regulated in macrophages treated by IL6 [GeneID=3569] for 400min: wildtype versus SOCS3 [GeneID=9021]. MSigDB C7: Immunologic Signatures (v6.0) 5.068E-5 7.064E-3
5.460E-2
6.466E-2
 3 199
8 M291 Genes down-regulated in allogeneic T cells after stimulation with dendritic cells from lymph nodes: mesenteric (mLN) versus peripheral (pLN). MSigDB C7: Immunologic Signatures (v6.0) 5.144E-5 7.064E-3
5.460E-2
6.563E-2
 3 200
9 18006812-TableS1 Human Lymphoma Piccaluga07 260genes GeneSigDB 5.456E-5 7.064E-3
5.460E-2
6.962E-2
 3 204
10 M12225 Up-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.536E-5 7.064E-3
5.460E-2
7.064E-2
 3 205
11 M11788 Selected genes down-regulated during invasion of lymphatic vessels during metastasis. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.416E-5 9.762E-3
7.545E-2
1.074E-1
 2 36
12 16273092-TableS1c Human InVitro Bild06 348genes GeneSigDB 1.022E-4 1.033E-2
7.986E-2
1.304E-1
 3 252
13 M13867 Genes up-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.071E-4 1.033E-2
7.986E-2
1.366E-1
 3 256
14 M12029 Genes selected in supervised analyses to discriminate cells expressing activated HRAS [GeneID=3265] oncogene from control cells expressing GFP. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.134E-4 1.033E-2
7.986E-2
1.447E-1
 3 261
15 M8364 Genes showing decreasing expression in brown preadipocytes with increasing ability of the cells to differentiate. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.380E-4 1.174E-2
9.072E-2
1.761E-1
 2 46
16 M12746 Genes up-regulated in NCI-H1299 cells (large cell neuroendocrine carcinoma) stably expressing SEMA3B [GeneID=7869]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.564E-4 1.247E-2
9.640E-2
1.995E-1
 3 291
17 12972399-Table1 Mouse Lung not cancer Vuillemenot04 64genes GeneSigDB 1.766E-4 1.325E-2
1.024E-1
2.253E-1
 2 52
18 16979889-Table2 Human Breast Li06 60genes GeneSigDB 1.976E-4 1.401E-2
1.083E-1
2.522E-1
 2 55
19 15895078-FigureS2 Mouse StemCell Tseng05 87genes GeneSigDB 3.296E-4 2.214E-2
1.711E-1
4.206E-1
 2 71
20 M2131 Genes up-regulated in RS4;11 cells (MLL, mixed lineage leukemia) in response to SB216763 [PubChem=176158], an inhibitor of GSK3B [GeneID=2932]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.900E-4 2.488E-2
1.923E-1
4.976E-1
 3 397
21 M19488 Genes up-regulated in nasopharyngeal carcinoma (NPC) positive for LMP1 [GeneID=9260], a latent gene of Epstein-Barr virus (EBV). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.225E-4 2.567E-2
1.984E-1
5.391E-1
 3 408
22 M2232 Genes bound by ESR1 [GeneID=2099] and down-regulated by estradiol [PubChem=5757] in MCF-7 cells (breast cancer). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.060E-4 2.935E-2
2.268E-1
6.457E-1
 2 88
23 17683608-TableS1 Mouse StemCell Ulloa-Montoya07 546genes GeneSigDB 5.663E-4 3.142E-2
2.428E-1
7.226E-1
 3 451
24 M12602 Genes positively correlated with recurrence free survival in patients with hepatitis B-related (HBV) hepatocellular carcinoma (HCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.193E-4 3.491E-2
2.698E-1
9.178E-1
 2 105
25 12941840-Table1 Human Lung Taxman03 151genes GeneSigDB 1.167E-3 3.491E-2
2.698E-1
1.000E0
 2 134
26 M13907 Down-regulated in brown preadipocytes with IRS1 [GeneID=3667] knockout vs wild type controls; the knockouts have severe defects in adipocyte differentiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.184E-3 3.491E-2
2.698E-1
1.000E0
 2 135
27 M11672 Genes from the blue module which are up-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.184E-3 3.491E-2
2.698E-1
1.000E0
 2 135
28 15785748-Table3 Human Uterine Santin05 178genes GeneSigDB 1.478E-3 3.491E-2
2.698E-1
1.000E0
 2 151
29 12747878-Table2 Human Breast Huang03 176genes LNmetastasis GeneSigDB 1.537E-3 3.491E-2
2.698E-1
1.000E0
 2 154
30 18667080-TableS4 Human StemCell Kocer08 185genes GeneSigDB 1.637E-3 3.491E-2
2.698E-1
1.000E0
 2 159
31 M11011 Genes down-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.637E-3 3.491E-2
2.698E-1
1.000E0
 2 159
32 17183660-TableS1a Mouse Breast Bacac06 256genes StromaUp GeneSigDB 1.657E-3 3.491E-2
2.698E-1
1.000E0
 2 160
33 M9113 Genes down-regulated in CD4 T conv: control versus over-expression of IRF4 and FOXP3 [GeneID=3662;50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.657E-3 3.491E-2
2.698E-1
1.000E0
 2 160
34 M2582 Genes up-regulated in the HSC non-supportive stromal cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.698E-3 3.491E-2
2.698E-1
1.000E0
 2 162
35 18381423-SuppTable1c Human StemCell Riggi08 206genes GeneSigDB 1.740E-3 3.491E-2
2.698E-1
1.000E0
 2 164
36 M9092 Genes up-regulated in CD4 T conv: control versus over-expression of XBP1 [GeneID=7494]. MSigDB C7: Immunologic Signatures (v6.0) 1.803E-3 3.491E-2
2.698E-1
1.000E0
 2 167
37 M8578 Genes up-regulated in Th17 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 1.911E-3 3.491E-2
2.698E-1
1.000E0
 2 172
38 M15588 Genes up-regulated in CD34+ [GeneID=947] hematopoetic cells by expression of NUP98-HOXA9 fusion [GeneID=4928;3205] off a retroviral vector at 16 days after transduction. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.978E-3 3.491E-2
2.698E-1
1.000E0
 2 175
39 16151515-TableS3 Mouse StemCell Forsberg05 362genes GeneSigDB 2.183E-3 3.491E-2
2.698E-1
1.000E0
 2 184
40 M10196 The 'ER-alpha profile': genes down-regulated in T47D cells (breast cancer, ESR2 [GeneID=2100] Tet-Off) upon activation of ESR1 [GeneID=2099] by estradiol (E2) [PubChem=5757]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.332E-3 3.491E-2
2.698E-1
1.000E0
 1 6
41 M7544 Genes down-regulated in untreated double positive thymocytes: wildtype versus ELK4 [GeneID=2005] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.373E-3 3.491E-2
2.698E-1
1.000E0
 2 192
42 M4207 Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 0.5 h versus the untreated cells at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 2.422E-3 3.491E-2
2.698E-1
1.000E0
 2 194
43 17880687-TableS4 Human Embryo Heim07 273genes GeneSigDB 2.447E-3 3.491E-2
2.698E-1
1.000E0
 2 195
44 M8683 Genes up-regulated in monocytes (24h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 2.472E-3 3.491E-2
2.698E-1
1.000E0
 2 196
45 M5878 Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus untreated monocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 3.491E-2
2.698E-1
1.000E0
 2 197
46 M8708 Genes up-regulated in bone marrow-derived macrophages with heterozygous MLL4 [GeneID=9757] knockout: control versus treated with LPS for 2h. MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 3.491E-2
2.698E-1
1.000E0
 2 197
47 M7977 Genes up-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout: control versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 3.491E-2
2.698E-1
1.000E0
 2 197
48 16365179-TableA2 Human HeadandNeck Bredel06 329genes GeneSigDB 2.521E-3 3.491E-2
2.698E-1
1.000E0
 2 198
49 M4192 Genes up-regulated in comparison of untreated CD4 [GeneID=920] T cells at 0 h versus the cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 2.521E-3 3.491E-2
2.698E-1
1.000E0
 2 198
50 M6104 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL4 [GeneID=3565] (6h). MSigDB C7: Immunologic Signatures (v6.0) 2.521E-3 3.491E-2
2.698E-1
1.000E0
 2 198
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 9 input genes in category / 1315 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Lungmap Mouse Lung PND1 MyoFB Subtype All subclasses Lungmap Mouse Lung PND1 MyoFB Subtype All subclasses Lungmap CCHMC 4.069E-6 2.234E-3 1.733E-2 5.350E-3 3 81
2 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn GlobusPallidus Top 200 Genes BrainMap 7.341E-6 2.234E-3 1.733E-2 9.653E-3 4 346
3 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Col15a1 Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Col15a1 Top 200 Genes 8.125E-6 2.234E-3 1.733E-2 1.068E-2 4 355
4 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Col15a1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Col15a1 Top 200 Genes BrainMap 8.125E-6 2.234E-3 1.733E-2 1.068E-2 4 355
5 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Pdgfa Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Pdgfa Top 200 Genes BrainMap 8.493E-6 2.234E-3 1.733E-2 1.117E-2 4 359
6 GSM538282 500 Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3 Immgen.org, GSE15907 1.652E-5 3.621E-3 2.809E-2 2.172E-2 4 425
7 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Overall Top 200 Genes BrainMap 5.083E-5 7.228E-3
5.608E-2
6.685E-2
 3 188
8 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf Polydendrocyte.oligodendrocytes.Trf Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf Polydendrocyte.oligodendrocytes.Trf Overall Top 200 Genes BrainMap 5.246E-5 7.228E-3
5.608E-2
6.899E-2
 3 190
9 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf Polydendrocyte.oligodendrocytes.Trf Top 200 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf Polydendrocyte.oligodendrocytes.Trf Top 200 BrainMap 5.246E-5 7.228E-3
5.608E-2
6.899E-2
 3 190
10 gudmap developingLowerUrinaryTract e14.5 Genital tubercle F 1000 k1 DevelopingLowerUrinaryTract e14.5 Genital tubercle F emap-6706 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.496E-5 7.228E-3
5.608E-2
7.228E-2
 3 193
11 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-D Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-D Lungmap CCHMC 9.255E-5 8.529E-3
6.618E-2
1.217E-1
 3 230
12 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-E Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-E Lungmap CCHMC 9.864E-5 8.529E-3
6.618E-2
1.297E-1
 3 235
13 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-F Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-F Lungmap CCHMC 1.063E-4 8.529E-3
6.618E-2
1.398E-1
 3 241
14 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-A Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-A Lungmap CCHMC 1.089E-4 8.529E-3
6.618E-2
1.432E-1
 3 243
15 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-C Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-C Lungmap CCHMC 1.103E-4 8.529E-3
6.618E-2
1.450E-1
 3 244
16 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-G Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-G Lungmap CCHMC 1.103E-4 8.529E-3
6.618E-2
1.450E-1
 3 244
17 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-B Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-B Lungmap CCHMC 1.103E-4 8.529E-3
6.618E-2
1.450E-1
 3 244
18 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k4 1000 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.346E-4 8.725E-3
6.770E-2
1.770E-1
 3 261
19 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Oligodendrocyte Subtype oligodendrocytes.Mbp Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Oligodendrocyte Subtype oligodendrocytes.Mbp Top 200 Genes 1.455E-4 8.725E-3
6.770E-2
1.914E-1
 3 268
20 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte Oligodendrocyte Subtype Oligodendrocyte.oligodendrocytes.Mbp Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte Oligodendrocyte Subtype Oligodendrocyte.oligodendrocytes.Mbp Top 200 Genes BrainMap 1.455E-4 8.725E-3
6.770E-2
1.914E-1
 3 268
21 Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype mesenchymal A Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype mesenchymal A Top 200 Genes 1.571E-4 8.725E-3
6.770E-2
2.065E-1
 3 275
22 Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype mesenchymal A E18.5 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype mesenchymal A E18.5 Top 200 Genes 1.571E-4 8.725E-3
6.770E-2
2.065E-1
 3 275
23 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes Oligodendrocyte.Pdgfa-hi oligodendrocytes Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes Oligodendrocyte.Pdgfa-hi oligodendrocytes Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Top 200 Genes BrainMap 1.674E-4 8.725E-3
6.770E-2
2.201E-1
 3 281
24 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr Entopeduncular Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr Entopeduncular Top 200 Genes BrainMap 1.709E-4 8.725E-3
6.770E-2
2.248E-1
 3 283
25 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr SubstantiaNigra Top 200 Genes BrainMap 1.782E-4 8.725E-3
6.770E-2
2.343E-1
 3 287
26 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Thalamus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Thalamus Top 200 Genes BrainMap 1.952E-4 8.725E-3
6.770E-2
2.566E-1
 3 296
27 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Subtype Polydendrocyte.oligodendrocytes.Trf Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Subtype Polydendrocyte.oligodendrocytes.Trf Top 200 Genes BrainMap 1.991E-4 8.725E-3
6.770E-2
2.618E-1
 3 298
28 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Subtype oligodendrocytes.Trf Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Subtype oligodendrocytes.Trf Top 200 Genes 1.991E-4 8.725E-3
6.770E-2
2.618E-1
 3 298
29 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr.Ctps Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr.Ctps Top 200 Genes BrainMap 2.091E-4 8.725E-3
6.770E-2
2.749E-1
 3 303
30 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Oligodendrocyte Top 200 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Oligodendrocyte Top 200 2.194E-4 8.725E-3
6.770E-2
2.885E-1
 3 308
31 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte Oligodendrocyte Top 200 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte Oligodendrocyte Top 200 BrainMap 2.194E-4 8.725E-3
6.770E-2
2.885E-1
 3 308
32 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Nnat Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Nnat Top 200 Genes BrainMap 2.236E-4 8.725E-3
6.770E-2
2.941E-1
 3 310
33 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Nnat Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Nnat Top 200 Genes 2.236E-4 8.725E-3
6.770E-2
2.941E-1
 3 310
34 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr.Pdgfa Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr.Pdgfa Top 200 Genes BrainMap 2.279E-4 8.725E-3
6.770E-2
2.997E-1
 3 312
35 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr GlobusPallidus Top 200 Genes BrainMap 2.322E-4 8.725E-3
6.770E-2
3.054E-1
 3 314
36 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Coch Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Coch Top 200 Genes 2.688E-4 9.209E-3
7.145E-2
3.535E-1
 3 330
37 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage - intermediate - unactivated PND01-03 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage - intermediate - unactivated PND01-03 Top 200 Genes 2.712E-4 9.209E-3
7.145E-2
3.566E-1
 3 331
38 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Coch Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Coch Top 200 Genes BrainMap 2.712E-4 9.209E-3
7.145E-2
3.566E-1
 3 331
39 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf.Klk6 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf.Klk6 Top 200 Genes BrainMap 2.736E-4 9.209E-3
7.145E-2
3.598E-1
 3 332
40 GSM403988 500 CD positive, CD19 Control, 19+ 4- 8-, Spleen, avg-6 Immgen.org, GSE15907 2.909E-4 9.209E-3
7.145E-2
3.826E-1
 3 339
41 GSM538225 500 B cells, B1a.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1- CD23- CD21/35-, Spleen, avg-3 Immgen.org, GSE15907 2.960E-4 9.209E-3
7.145E-2
3.892E-1
 3 341
42 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr.Opalin Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr.Opalin Top 200 Genes BrainMap 2.960E-4 9.209E-3
7.145E-2
3.892E-1
 3 341
43 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr Thalamus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.oligodendrocytes.Trf.Tnr Polydendrocyte.oligodendrocytes.Trf.Tnr Subtype Polydendrocyte.oligodendrocytes.Trf.Tnr Thalamus Top 200 Genes BrainMap 3.011E-4 9.209E-3
7.145E-2
3.960E-1
 3 343
44 GSM854229 500 B cells, B1a.Sp, CD19+ CD45R+ IgM++ AA4.1- CD23- CD43+ CD5+, Spleen, avg-3 Immgen.org, GSE15907 3.116E-4 9.259E-3
7.184E-2
4.097E-1
 3 347
45 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte. .Trf Oligodendrocyte. .Trf Subtype Oligodendrocyte. .Trf Entopeduncular Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte. .Trf Oligodendrocyte. .Trf Subtype Oligodendrocyte. .Trf Entopeduncular Top 200 Genes BrainMap 3.169E-4 9.259E-3
7.184E-2
4.167E-1
 3 349
46 GSM538219 500 B cells, B.T3.Sp, IgD+ IgM+ CD45R+ CD24+ CD19+ AA4.1+ CD23+, Spleen, avg-3 Immgen.org, GSE15907 3.499E-4 1.000E-2
7.761E-2
4.601E-1
 3 361
47 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 3.821E-4 1.069E-2
8.295E-2
5.025E-1
 3 372
48 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Squamous Cell Carcinoma/3/3 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Squamous Cell Carcinoma/3/3 TCGA-Lung 4.123E-4 1.130E-2
8.764E-2
5.422E-1
 1 1
49 gudmap kidney adult JuxtaGlom Ren1 Captopr 500 kidney adult JuxtaGlom Ren1 Captopr top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.971E-4 1.329E-2
1.031E-1
6.537E-1
 3 407
50 GSM538282 100 Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3 Immgen.org, GSE15907 5.054E-4 1.329E-2
1.031E-1
6.646E-1
 2 83
Show 45 more annotations

15: Computational [Display Chart] 5 input genes in category / 35 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 9 input genes in category / 248 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-670-3p:TargetScan hsa-miR-670-3p TargetScan 1.401E-5 3.476E-3 2.118E-2 3.476E-3 3 402
2 hsa-miR-891b:PITA hsa-miR-891b:PITA TOP PITA 4.852E-4 3.212E-2
1.957E-1
1.203E-1
 2 268
3 hsa-miR-6716-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.982E-4 3.212E-2
1.957E-1
1.236E-1
 1 4
4 hsa-miR-3934-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.181E-4 3.212E-2
1.957E-1
1.285E-1
 2 277
5 hsa-miR-143-3p:TargetScan hsa-miR-143-3p TargetScan 8.007E-4 3.972E-2
2.420E-1
1.986E-1
 2 345

17: Drug [Display Chart] 9 input genes in category / 2791 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000005263 lysosphingomyelin Stitch 9.219E-12 2.573E-8 2.190E-7 2.573E-8 6 161
2 CID005311264 1-acetyl-sn-glycero-3-phosphocholine Stitch 4.384E-10 6.118E-7 5.207E-6 1.224E-6 6 305
3 CID000389046 N-palmitoyl-L-tyrosine Stitch 8.455E-10 7.866E-7 6.695E-6 2.360E-6 3 6
4 CID005497157 Brain Pi(4,5)p2 Stitch 1.479E-9 8.256E-7 7.027E-6 4.129E-6 3 7
5 CID003441849 AC1MPVH8 Stitch 1.498E-9 8.256E-7 7.027E-6 4.181E-6 4 44
6 CID000003987 oleoyl-lysophosphatidic acid Stitch 1.978E-9 8.256E-7 7.027E-6 5.521E-6 6 392
7 CID005311306 VPC12249 Stitch 2.366E-9 8.256E-7 7.027E-6 6.605E-6 3 8
8 CID000085997 N-palmitoyl-serine Stitch 2.366E-9 8.256E-7 7.027E-6 6.605E-6 3 8
9 CID000186213 fluoromethylene Stitch 3.549E-9 9.363E-7 7.969E-6 9.905E-6 3 9
10 CID005460104 phosphatidate Stitch 3.590E-9 9.363E-7 7.969E-6 1.002E-5 6 433
11 CID000005262 AC1L1JYL Stitch 3.690E-9 9.363E-7 7.969E-6 1.030E-5 6 435
12 CID000301119 AC1L6XQE Stitch 1.007E-8 2.343E-6 1.994E-5 2.811E-5 4 70
13 CID000011164 glycidol Stitch 1.920E-8 3.828E-6 3.258E-5 5.359E-5 3 15
14 CID005330524 PD173956 Stitch 1.920E-8 3.828E-6 3.258E-5 5.359E-5 3 15
15 CID000107969 FTY720 Stitch 5.632E-8 1.048E-5 8.920E-5 1.572E-4 4 107
16 CID005311257 LY320135 Stitch 8.526E-8 1.400E-5 1.191E-4 2.380E-4 3 24
17 CID000176878 aganodine Stitch 8.526E-8 1.400E-5 1.191E-4 2.380E-4 3 24
18 CID006432238 difluoromethylene Stitch 1.538E-7 2.384E-5 2.029E-4 4.292E-4 3 29
19 CID000001104 (2S,3R)-Sphingosine Stitch 1.685E-7 2.475E-5 2.107E-4 4.702E-4 5 390
20 CID000440919 AC1L9A6V Stitch 2.294E-7 3.202E-5 2.725E-4 6.403E-4 3 33
21 CID000447308 lysophosphatidylglycerol Stitch 3.265E-7 4.339E-5 3.693E-4 9.112E-4 3 37
22 CID000069990 phenylphosphonic dichloride Stitch 4.140E-7 4.621E-5 3.934E-4 1.155E-3 2 3
23 CID000120678 quinovic acid Stitch 4.140E-7 4.621E-5 3.934E-4 1.155E-3 2 3
24 CID000065758 RI-64 Stitch 4.140E-7 4.621E-5 3.934E-4 1.155E-3 2 3
25 CID000196156 4mupt Stitch 4.140E-7 4.621E-5 3.934E-4 1.155E-3 2 3
26 CID000002049 tyrphostin AG1296 Stitch 5.557E-7 5.965E-5 5.077E-4 1.551E-3 3 44
27 CID000002765 cirazoline Stitch 6.367E-7 6.582E-5 5.602E-4 1.777E-3 3 46
28 CID000072065 hebucol Stitch 8.277E-7 7.966E-5 6.781E-4 2.310E-3 2 4
29 CID000639684 benzoylsalireposide Stitch 8.277E-7 7.966E-5 6.781E-4 2.310E-3 2 4
30 CID000132276 8-acetyl-2-(dipropylamino)tetralin Stitch 1.379E-6 1.242E-4 1.057E-3 3.850E-3 2 5
31 CID000081923 3,5-heptanedione Stitch 1.379E-6 1.242E-4 1.057E-3 3.850E-3 2 5
32 CID000000520 dhS1P Stitch 1.912E-6 1.560E-4 1.328E-3 5.336E-3 3 66
33 CID000134928 4-methylumbelliferyl phenylphosphonate Stitch 2.069E-6 1.560E-4 1.328E-3 5.773E-3 2 6
34 CID000065874 saterinone Stitch 2.069E-6 1.560E-4 1.328E-3 5.773E-3 2 6
35 CID000335091 NSC343256 Stitch 2.069E-6 1.560E-4 1.328E-3 5.773E-3 2 6
36 CID000325952 AC1L6XCD Stitch 2.069E-6 1.560E-4 1.328E-3 5.773E-3 2 6
37 CID000188326 diadenosine diphosphate Stitch 2.069E-6 1.560E-4 1.328E-3 5.773E-3 2 6
38 CID000460605 1-dodecanoyllysolecithin Stitch 2.895E-6 2.098E-4 1.785E-3 8.081E-3 2 7
39 CID006338557 O-EC Stitch 2.931E-6 2.098E-4 1.785E-3 8.181E-3 3 76
40 CID000167253 phosphorothioate Stitch 3.309E-6 2.309E-4 1.965E-3 9.234E-3 4 296
41 CID006918114 11-keto-beta-boswellic acid Stitch 3.860E-6 2.627E-4 2.236E-3 1.077E-2 2 8
42 CID000002552 AC1L1DXN Stitch 4.259E-6 2.830E-4 2.409E-3 1.189E-2 3 86
43 CID000133738 cadeguomycin Stitch 4.961E-6 3.147E-4 2.679E-3 1.385E-2 2 9
44 CID003081662 ddUMP Stitch 4.961E-6 3.147E-4 2.679E-3 1.385E-2 2 9
45 CID000150911 1,3-DCG Stitch 5.569E-6 3.454E-4 2.940E-3 1.554E-2 3 94
46 CID003062886 2-(p-n-butylanilino)-2'-deoxyadenosine Stitch 6.200E-6 3.682E-4 3.134E-3 1.731E-2 2 10
47 CID000323607 NSC285223 Stitch 6.200E-6 3.682E-4 3.134E-3 1.731E-2 2 10
48 CID000004383 oleoylethanolamide Stitch 6.710E-6 3.902E-4 3.321E-3 1.873E-2 3 100
49 CID006433481 hygromycin A Stitch 6.914E-6 3.938E-4 3.352E-3 1.930E-2 3 101
50 CID000000199 agmatine Stitch 7.335E-6 4.094E-4 3.485E-3 2.047E-2 3 103
Show 45 more annotations

18: Disease [Display Chart] 9 input genes in category / 232 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C4049711 Lepidic Predominant Adenocarcinoma DisGeNET BeFree 4.638E-10 1.076E-7 6.485E-7 1.076E-7 4 24
2 C0235290 bitter taste DisGeNET BeFree 1.348E-4 9.911E-3
5.973E-2
 3.128E-2 2 32
3 C0220656 Malignant ascites DisGeNET BeFree 3.181E-4 9.911E-3
5.973E-2
7.380E-2
 2 49
4 C3811653 Experimental Organism Basal Cell Carcinoma DisGeNET BeFree 4.223E-4 9.911E-3
5.973E-2
9.798E-2
 3 286
5 C3809781 Cole disease DisGeNET Curated 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
6 cv:C1859727 Arterial calcification of infancy Clinical Variations 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
7 OMIN:613312 HYPOPHOSPHATEMIC RICKETS, AUTOSOMAL RECESSIVE, 2; ARHR2 OMIM 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
8 OMIN:208000 ARTERIAL CALCIFICATION, GENERALIZED, OF INFANCY; GACI OMIM 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
9 C0553757 Olfaction Disorders DisGeNET Curated 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
10 cv:CN181445 Cole disease Clinical Variations 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
11 C4025269 Generalized arterial calcification DisGeNET Curated 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
12 cv:C2750078 Hypophosphatemic rickets, autosomal recessive, 2 Clinical Variations 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
13 C2750078 Hypophosphatemic Rickets, Autosomal Recessive, 2 DisGeNET Curated 5.554E-4 9.911E-3
5.973E-2
1.288E-1
 1 1
14 C0040136 Thyroid Neoplasm DisGeNET Curated 6.763E-4 1.120E-2
6.750E-2
1.569E-1
 3 336
15 C0034069 Pulmonary Fibrosis DisGeNET Curated 9.309E-4 1.120E-2
6.750E-2
2.160E-1
 3 375
16 C0264955 Idiopathic arterial calcification of infancy DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
17 C4023065 Low serum calcitriol DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
18 C4024631 Renal hypophosphatemia DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
19 C0518988 Dental abscess DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
20 C0262621 SACROILIAC JOINT ABNORMALITY DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
21 C1833323 Rickets of the lower limbs DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
22 C4021028 Pseudo-fractures DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
23 C4023579 Abnormality of renal excretion DisGeNET Curated 1.110E-3 1.120E-2
6.750E-2
2.576E-1
 1 2
24 C1704272 Benign Prostatic Hyperplasia DisGeNET BeFree 1.240E-3 1.199E-2
7.222E-2
2.876E-1
 3 414
25 C1859727 Arterial calcification of infancy DisGeNET Curated 1.665E-3 1.380E-2
8.315E-2
3.864E-1
 1 3
26 C0342643 Autosomal recessive hypophosphatemic vitamin D refractory rickets DisGeNET Curated 1.665E-3 1.380E-2
8.315E-2
3.864E-1
 1 3
27 C1611184 Calcification of coronary artery DisGeNET Curated 1.665E-3 1.380E-2
8.315E-2
3.864E-1
 1 3
28 C1860107 Distal femoral bowing DisGeNET Curated 1.665E-3 1.380E-2
8.315E-2
3.864E-1
 1 3
29 C0030193 Pain DisGeNET Curated 1.809E-3 1.447E-2
8.722E-2
4.197E-1
 3 472
30 OMIN:602475 OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE; OPLL OMIM 2.220E-3 1.661E-2
1.001E-1
5.150E-1
 1 4
31 C1833667 Increased serum bone-specific alkaline phosphatase DisGeNET Curated 2.220E-3 1.661E-2
1.001E-1
5.150E-1
 1 4
32 20081125:Grant Type 1 diabetes GWAS 2.774E-3 1.893E-2
1.141E-1
6.436E-1
 1 5
33 C1838663 Enlargement of the wrists DisGeNET Curated 2.774E-3 1.893E-2
1.141E-1
6.436E-1
 1 5
34 C1859698 Contractures of the large joints DisGeNET Curated 2.774E-3 1.893E-2
1.141E-1
6.436E-1
 1 5
35 C0035317 Retinal Hemorrhage DisGeNET Curated 3.328E-3 1.980E-2
1.193E-1
7.721E-1
 1 6
36 C0694533 Moderate obesity DisGeNET BeFree 3.328E-3 1.980E-2
1.193E-1
7.721E-1
 1 6
37 C4020957 Abnormal trabecular bone morphology DisGeNET Curated 3.328E-3 1.980E-2
1.193E-1
7.721E-1
 1 6
38 C4022001 Abnormality of the cerebral vasculature DisGeNET Curated 3.328E-3 1.980E-2
1.193E-1
7.721E-1
 1 6
39 C0023221 Leg Length Inequality DisGeNET Curated 3.328E-3 1.980E-2
1.193E-1
7.721E-1
 1 6
40 C1865343 OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT OF SPINE DisGeNET Curated 3.882E-3 2.144E-2
1.292E-1
9.006E-1
 1 7
41 C1845169 Renal phosphate wasting DisGeNET Curated 3.882E-3 2.144E-2
1.292E-1
9.006E-1
 1 7
42 C1282952 Enthesitis DisGeNET Curated 3.882E-3 2.144E-2
1.292E-1
9.006E-1
 1 7
43 C0149721 Left Ventricular Hypertrophy DisGeNET Curated 4.151E-3 2.240E-2
1.350E-1
9.630E-1
 2 179
44 C0005395 Bile Duct Diseases DisGeNET Curated 4.435E-3 2.339E-2
1.409E-1
1.000E0
 1 8
45 C0002982 Angioid Streaks DisGeNET Curated 4.989E-3 2.572E-2
1.550E-1
1.000E0
 1 9
46 C0553665 Skin endocrine disorder DisGeNET BeFree 5.104E-3 2.574E-2
1.551E-1
1.000E0
 2 199
47 C0242339 Dyslipidemias DisGeNET Curated 5.562E-3 2.746E-2
1.655E-1
1.000E0
 2 208
48 C0162291 Retinal ischemia DisGeNET BeFree 6.094E-3 2.946E-2
1.775E-1
1.000E0
 1 11
49 C0282201 Phosphate Diabetes DisGeNET BeFree 7.199E-3 3.340E-2
2.013E-1
1.000E0
 1 13
50 C3540852 Rickets, X-Linked Hypophosphatemic DisGeNET BeFree 7.199E-3 3.340E-2
2.013E-1
1.000E0
 1 13
Show 45 more annotations