Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc69_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 60 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0046943 carboxylic acid transmembrane transporter activity 1.553E-8 3.381E-7 1.582E-6 9.315E-7 4 141
2 GO:0015293 symporter activity 1.643E-8 3.381E-7 1.582E-6 9.860E-7 4 143
3 GO:0005342 organic acid transmembrane transporter activity 1.690E-8 3.381E-7 1.582E-6 1.014E-6 4 144
4 GO:0008514 organic anion transmembrane transporter activity 4.441E-8 6.662E-7 3.118E-6 2.665E-6 4 183
5 GO:0015501 glutamate:sodium symporter activity 5.744E-8 6.892E-7 3.226E-6 3.446E-6 2 2
6 GO:0015291 secondary active transmembrane transporter activity 1.235E-7 1.235E-6 5.778E-6 7.409E-6 4 236
7 GO:0015179 L-amino acid transmembrane transporter activity 2.413E-7 2.068E-6 9.678E-6 1.448E-5 3 55
8 GO:0008509 anion transmembrane transporter activity 3.105E-7 2.329E-6 1.090E-5 1.863E-5 4 297
9 GO:0005314 high-affinity glutamate transmembrane transporter activity 5.742E-7 3.828E-6 1.791E-5 3.445E-5 2 5
10 GO:0022804 active transmembrane transporter activity 6.935E-7 4.113E-6 1.925E-5 4.161E-5 4 363
11 GO:0015171 amino acid transmembrane transporter activity 7.540E-7 4.113E-6 1.925E-5 4.524E-5 3 80
12 GO:0000099 sulfur amino acid transmembrane transporter activity 1.206E-6 6.028E-6 2.821E-5 7.233E-5 2 7
13 GO:0015294 solute:cation symporter activity 1.394E-6 6.433E-6 3.011E-5 8.363E-5 3 98
14 GO:0005283 amino acid:sodium symporter activity 3.787E-6 1.623E-5 7.595E-5 2.272E-4 2 12
15 GO:0005313 L-glutamate transmembrane transporter activity 4.475E-6 1.790E-5 8.376E-5 2.685E-4 2 13
16 GO:0015172 acidic amino acid transmembrane transporter activity 5.220E-6 1.957E-5 9.161E-5 3.132E-4 2 14
17 GO:0005416 amino acid:cation symporter activity 6.882E-6 2.429E-5 1.137E-4 4.129E-4 2 16
18 GO:0005343 organic acid:sodium symporter activity 1.719E-5 5.729E-5 2.681E-4 1.031E-3 2 25
19 GO:1901682 sulfur compound transmembrane transporter activity 2.325E-5 7.343E-5 3.436E-4 1.395E-3 2 29
20 GO:0005310 dicarboxylic acid transmembrane transporter activity 2.662E-5 7.987E-5 3.738E-4 1.597E-3 2 31
21 GO:0015175 neutral amino acid transmembrane transporter activity 3.023E-5 8.636E-5 4.041E-4 1.814E-3 2 33
22 GO:0015296 anion:cation symporter activity 6.447E-5 1.753E-4 8.205E-4 3.868E-3 2 48
23 GO:0015370 solute:sodium symporter activity 6.720E-5 1.753E-4 8.205E-4 4.032E-3 2 49
24 GO:0015538 sialic acid:proton symporter activity 2.679E-4 5.742E-4 2.687E-3 1.608E-2 1 1
25 GO:0033229 cysteine transmembrane transporter activity 2.679E-4 5.742E-4 2.687E-3 1.608E-2 1 1
26 GO:0015195 L-threonine transmembrane transporter activity 2.679E-4 5.742E-4 2.687E-3 1.608E-2 1 1
27 GO:0034590 L-hydroxyproline transmembrane transporter activity 2.679E-4 5.742E-4 2.687E-3 1.608E-2 1 1
28 GO:0015136 sialic acid transmembrane transporter activity 2.679E-4 5.742E-4 2.687E-3 1.608E-2 1 1
29 GO:0015081 sodium ion transmembrane transporter activity 5.197E-4 1.075E-3 5.032E-3 3.118E-2 2 136
30 GO:0022853 active ion transmembrane transporter activity 8.584E-4 1.717E-3 8.034E-3
5.150E-2
 2 175
31 GO:0015184 L-cystine transmembrane transporter activity 1.071E-3 2.074E-3 9.705E-3
6.428E-2
 1 4
32 GO:0015186 L-glutamine transmembrane transporter activity 1.339E-3 2.511E-3 1.175E-2
8.035E-2
 1 5
33 GO:0022858 alanine transmembrane transporter activity 1.874E-3 3.308E-3 1.548E-2
1.125E-1
 1 7
34 GO:0015180 L-alanine transmembrane transporter activity 1.874E-3 3.308E-3 1.548E-2
1.125E-1
 1 7
35 GO:0015193 L-proline transmembrane transporter activity 2.142E-3 3.672E-3 1.718E-2
1.285E-1
 1 8
36 GO:0015194 L-serine transmembrane transporter activity 2.409E-3 3.907E-3 1.828E-2
1.446E-1
 1 9
37 GO:0022889 serine transmembrane transporter activity 2.409E-3 3.907E-3 1.828E-2
1.446E-1
 1 9
38 GO:0016595 glutamate binding 3.479E-3 5.493E-3 2.571E-2
2.087E-1
 1 13
39 GO:0015077 monovalent inorganic cation transmembrane transporter activity 3.869E-3 5.952E-3 2.786E-2
2.321E-1
 2 375
40 GO:0005351 carbohydrate:proton symporter activity 4.280E-3 6.264E-3 2.931E-2
2.568E-1
 1 16
41 GO:0005402 carbohydrate:cation symporter activity 4.280E-3 6.264E-3 2.931E-2
2.568E-1
 1 16
42 GO:0072349 modified amino acid transmembrane transporter activity 4.814E-3 6.773E-3 3.170E-2
2.888E-1
 1 18
43 GO:0005216 ion channel activity 4.922E-3 6.773E-3 3.170E-2
2.953E-1
 2 424
44 GO:0046873 metal ion transmembrane transporter activity 4.967E-3 6.773E-3 3.170E-2
2.980E-1
 2 426
45 GO:0022838 substrate-specific channel activity 5.244E-3 6.992E-3 3.272E-2
3.147E-1
 2 438
46 GO:0015267 channel activity 6.019E-3 7.715E-3 3.611E-2
3.611E-1
 2 470
47 GO:0022803 passive transmembrane transporter activity 6.044E-3 7.715E-3 3.611E-2
3.626E-1
 2 471
48 GO:0015295 solute:proton symporter activity 7.214E-3 9.018E-3 4.220E-2
4.329E-1
 1 27
49 GO:0051119 sugar transmembrane transporter activity 8.812E-3 1.079E-2
5.050E-2
5.287E-1
 1 33
50 GO:1901505 carbohydrate derivative transmembrane transporter activity 9.876E-3 1.185E-2
5.546E-2
5.925E-1
 1 37
Show 45 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 97 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:1905039 carboxylic acid transmembrane transport 5.735E-9 3.102E-7 1.600E-6 5.563E-7 4 110
2 GO:1903825 organic acid transmembrane transport 6.396E-9 3.102E-7 1.600E-6 6.204E-7 4 113
3 GO:0006865 amino acid transport 3.098E-8 1.002E-6 5.165E-6 3.005E-6 4 167
4 GO:0098656 anion transmembrane transport 2.012E-7 4.880E-6 2.516E-5 1.952E-5 4 266
5 GO:0070779 D-aspartate import across plasma membrane 3.459E-7 5.037E-6 2.598E-5 3.356E-5 2 4
6 GO:0070777 D-aspartate transport 3.459E-7 5.037E-6 2.598E-5 3.356E-5 2 4
7 GO:0003333 amino acid transmembrane transport 4.632E-7 5.037E-6 2.598E-5 4.493E-5 3 68
8 GO:0015807 L-amino acid transport 4.842E-7 5.037E-6 2.598E-5 4.697E-5 3 69
9 GO:0046942 carboxylic acid transport 4.951E-7 5.037E-6 2.598E-5 4.802E-5 4 333
10 GO:0015849 organic acid transport 5.193E-7 5.037E-6 2.598E-5 5.037E-5 4 337
11 GO:0042940 D-amino acid transport 8.647E-7 6.990E-6 3.605E-5 8.387E-5 2 6
12 GO:0000101 sulfur amino acid transport 8.647E-7 6.990E-6 3.605E-5 8.387E-5 2 6
13 GO:0015711 organic anion transport 1.833E-6 1.368E-5 7.054E-5 1.778E-4 4 462
14 GO:0051938 L-glutamate import 2.593E-6 1.797E-5 9.265E-5 2.515E-4 2 10
15 GO:0015810 aspartate transmembrane transport 3.169E-6 2.049E-5 1.057E-4 3.074E-4 2 11
16 GO:0015740 C4-dicarboxylate transport 4.493E-6 2.724E-5 1.405E-4 4.358E-4 2 13
17 GO:0043090 amino acid import 1.329E-5 7.585E-5 3.912E-4 1.289E-3 2 22
18 GO:0015813 L-glutamate transmembrane transport 1.726E-5 9.300E-5 4.796E-4 1.674E-3 2 25
19 GO:0015800 acidic amino acid transport 2.335E-5 1.192E-4 6.147E-4 2.265E-3 2 29
20 GO:1902475 L-alpha-amino acid transmembrane transport 2.851E-5 1.383E-4 7.131E-4 2.766E-3 2 32
21 GO:0072348 sulfur compound transport 3.419E-5 1.579E-4 8.145E-4 3.317E-3 2 35
22 GO:0015804 neutral amino acid transport 3.620E-5 1.596E-4 8.231E-4 3.511E-3 2 36
23 GO:0014047 glutamate secretion 7.904E-5 3.333E-4 1.719E-3 7.666E-3 2 53
24 GO:1903712 cysteine transmembrane transport 2.685E-4 9.301E-4 4.797E-3 2.604E-2 1 1
25 GO:0015739 sialic acid transport 2.685E-4 9.301E-4 4.797E-3 2.604E-2 1 1
26 GO:0015826 threonine transport 2.685E-4 9.301E-4 4.797E-3 2.604E-2 1 1
27 GO:0034589 hydroxyproline transport 2.685E-4 9.301E-4 4.797E-3 2.604E-2 1 1
28 GO:0042883 cysteine transport 2.685E-4 9.301E-4 4.797E-3 2.604E-2 1 1
29 GO:0006835 dicarboxylic acid transport 2.939E-4 9.830E-4 5.069E-3 2.851E-2 2 102
30 GO:0046717 acid secretion 4.481E-4 1.449E-3 7.472E-3 4.347E-2 2 126
31 GO:0015811 L-cystine transport 1.074E-3 3.359E-3 1.732E-2
1.041E-1
 1 4
32 GO:0006868 glutamine transport 1.610E-3 4.880E-3 2.517E-2
1.562E-1
 1 6
33 GO:0015808 L-alanine transport 1.878E-3 5.358E-3 2.763E-2
1.822E-1
 1 7
34 GO:0047484 regulation of response to osmotic stress 1.878E-3 5.358E-3 2.763E-2
1.822E-1
 1 7
35 GO:0035524 proline transmembrane transport 2.146E-3 5.948E-3 3.068E-2
2.082E-1
 1 8
36 GO:0015824 proline transport 2.414E-3 6.329E-3 3.264E-2
2.342E-1
 1 9
37 GO:0015825 L-serine transport 2.414E-3 6.329E-3 3.264E-2
2.342E-1
 1 9
38 GO:0072584 caveolin-mediated endocytosis 2.682E-3 6.504E-3 3.354E-2
2.602E-1
 1 10
39 GO:0032329 serine transport 2.682E-3 6.504E-3 3.354E-2
2.602E-1
 1 10
40 GO:0032328 alanine transport 2.682E-3 6.504E-3 3.354E-2
2.602E-1
 1 10
41 GO:0071397 cellular response to cholesterol 3.486E-3 8.247E-3 4.253E-2
3.381E-1
 1 13
42 GO:0036315 cellular response to sterol 4.289E-3 9.905E-3
5.108E-2
4.160E-1
 1 16
43 GO:0070723 response to cholesterol 6.161E-3 1.390E-2
7.167E-2
5.976E-1
 1 23
44 GO:0036314 response to sterol 6.962E-3 1.501E-2
7.739E-2
6.753E-1
 1 26
45 GO:0010460 positive regulation of heart rate 6.962E-3 1.501E-2
7.739E-2
6.753E-1
 1 26
46 GO:0072337 modified amino acid transport 8.296E-3 1.749E-2
9.022E-2
8.047E-1
 1 31
47 GO:0010259 multicellular organism aging 9.363E-3 1.932E-2
9.965E-2
9.082E-1
 1 35
48 GO:0045823 positive regulation of heart contraction 1.096E-2 2.215E-2
1.142E-1
1.000E0
 1 41
49 GO:0046326 positive regulation of glucose import 1.256E-2 2.486E-2
1.282E-1
1.000E0
 1 47
50 GO:0010828 positive regulation of glucose transmembrane transport 1.442E-2 2.797E-2
1.442E-1
1.000E0
 1 54
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 38 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016324 apical plasma membrane 2.974E-3 4.726E-2
1.998E-1
1.130E-1
 2 335
2 GO:0098793 presynapse 3.079E-3 4.726E-2
1.998E-1
1.170E-1
 2 341
3 GO:0045177 apical part of cell 4.809E-3 4.726E-2
1.998E-1
1.828E-1
 2 428
4 GO:0030673 axolemma 4.975E-3 4.726E-2
1.998E-1
1.890E-1
 1 19

4: Human Phenotype [Display Chart] 5 input genes in category / 94 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 4 input genes in category / 107 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0011854 cerebral edema 3.131E-6 3.351E-4 1.761E-3 3.351E-4 2 8
2 MP:0008025 brain vacuoles 7.832E-5 4.190E-3 2.202E-2 8.380E-3 2 38
3 MP:0003871 abnormal myelin sheath morphology 3.501E-4 1.249E-2
6.562E-2
 3.746E-2 2 80
4 MP:0001330 abnormal optic nerve morphology 1.179E-3 1.972E-2
1.036E-1
1.261E-1
 2 147
5 MP:0000780 abnormal corpus callosum morphology 1.260E-3 1.972E-2
1.036E-1
1.348E-1
 2 152
6 MP:0008219 abnormal dorsal telencephalic commissure morphology 1.310E-3 1.972E-2
1.036E-1
1.401E-1
 2 155
7 MP:0010014 hippocampus pyramidal cell degeneration 1.544E-3 1.972E-2
1.036E-1
1.653E-1
 1 4
8 MP:0000947 convulsive seizures 1.704E-3 1.972E-2
1.036E-1
1.824E-1
 2 177
9 MP:0002199 abnormal brain commissure morphology 1.860E-3 1.972E-2
1.036E-1
1.991E-1
 2 185
10 MP:0009357 abnormal seizure response to inducing agent 2.065E-3 1.972E-2
1.036E-1
2.209E-1
 2 195
11 MP:0030613 dicarboxylic aciduria 2.316E-3 1.972E-2
1.036E-1
2.478E-1
 1 6
12 MP:0008489 slow postnatal weight gain 2.459E-3 1.972E-2
1.036E-1
2.631E-1
 2 213
13 MP:0000778 abnormal nervous system tract morphology 2.645E-3 1.972E-2
1.036E-1
2.830E-1
 2 221
14 MP:0030612 organic aciduria 2.702E-3 1.972E-2
1.036E-1
2.891E-1
 1 7
15 MP:0005404 abnormal axon morphology 2.764E-3 1.972E-2
1.036E-1
2.958E-1
 2 226
16 MP:0008026 abnormal brain white matter morphology 3.036E-3 2.030E-2
1.067E-1
3.249E-1
 2 237
17 MP:0000954 decreased oligodendrocyte progenitor number 4.243E-3 2.671E-2
1.403E-1
4.540E-1
 1 11
18 MP:0001056 abnormal cranial nerve morphology 4.735E-3 2.815E-2
1.479E-1
5.066E-1
 2 297
19 MP:0004267 abnormal optic tract morphology 5.398E-3 2.888E-2
1.517E-1
5.776E-1
 1 14
20 MP:0006219 optic nerve degeneration 5.398E-3 2.888E-2
1.517E-1
5.776E-1
 1 14
21 MP:0002272 abnormal nervous system electrophysiology 6.866E-3 3.498E-2
1.838E-1
7.347E-1
 2 359
22 MP:0002064 seizures 8.072E-3 3.926E-2
2.063E-1
8.637E-1
 2 390
23 MP:0008406 increased cellular sensitivity to hydrogen peroxide 8.856E-3 4.120E-2
2.165E-1
9.476E-1
 1 23
24 MP:0008917 abnormal oligodendrocyte physiology 1.001E-2 4.462E-2
2.344E-1
1.000E0
 1 26
25 MP:0008415 abnormal neurite morphology 1.137E-2 4.573E-2
2.403E-1
1.000E0
 2 465
26 MP:0008948 decreased neuron number 1.141E-2 4.573E-2
2.403E-1
1.000E0
 2 466
27 MP:0002944 increased lactate dehydrogenase level 1.154E-2 4.573E-2
2.403E-1
1.000E0
 1 30
28 MP:0008916 abnormal astrocyte physiology 1.231E-2 4.703E-2
2.471E-1
1.000E0
 1 32
29 MP:0008263 abnormal hippocampus CA1 region morphology 1.345E-2 4.935E-2
2.593E-1
1.000E0
 1 35
30 MP:0002176 increased brain weight 1.384E-2 4.935E-2
2.593E-1
1.000E0
 1 36
Show 25 more annotations

6: Domain [Display Chart] 5 input genes in category / 12 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1.10.3860.10 - Gene3D 3.193E-10 6.386E-10 1.982E-9 3.832E-9 3 7
2 PF00375 SDF Pfam 3.193E-10 6.386E-10 1.982E-9 3.832E-9 3 7
3 IPR018107 Na-dicarboxylate symporter CS InterPro 3.193E-10 6.386E-10 1.982E-9 3.832E-9 3 7
4 IPR001991 Na-dicarboxylate symporter InterPro 3.193E-10 6.386E-10 1.982E-9 3.832E-9 3 7
5 PS00713 NA DICARBOXYL SYMP 1 PROSITE 3.193E-10 6.386E-10 1.982E-9 3.832E-9 3 7
6 PS00714 NA DICARBOXYL SYMP 2 PROSITE 3.193E-10 6.386E-10 1.982E-9 3.832E-9 3 7
7 PD492528 PD492528 ProDom 2.669E-4 4.003E-4 1.242E-3 3.203E-3 1 1
8 IPR033280 Membrane MLC1 InterPro 2.669E-4 4.003E-4 1.242E-3 3.203E-3 1 1
9 IPR011701 MFS InterPro 2.038E-2 2.446E-2
7.591E-2
2.446E-1
 1 77
10 PF07690 MFS 1 Pfam 2.038E-2 2.446E-2
7.591E-2
2.446E-1
 1 77
11 PS50850 MFS PROSITE 2.850E-2 3.109E-2
9.647E-2
3.419E-1
 1 108
12 IPR020846 MFS dom InterPro 3.526E-2 3.526E-2
1.094E-1
4.231E-1
 1 134
Show 7 more annotations

7: Pathway [Display Chart] 4 input genes in category / 21 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269908 Transport of inorganic cations/anions and amino acids/oligopeptides BioSystems: REACTOME 5.158E-9 1.083E-7 3.948E-7 1.083E-7 4 107
2 1269907 SLC-mediated transmembrane transport BioSystems: REACTOME 2.767E-7 2.905E-6 1.059E-5 5.810E-6 4 287
3 1268771 Glutamate Neurotransmitter Release Cycle BioSystems: REACTOME 2.132E-5 1.492E-4 5.440E-4 4.477E-4 2 24
4 P00037 Ionotropic glutamate receptor pathway PantherDB 7.976E-5 4.124E-4 1.503E-3 1.675E-3 2 46
5 1268768 Neurotransmitter Release Cycle BioSystems: REACTOME 9.820E-5 4.124E-4 1.503E-3 2.062E-3 2 51
6 P00039 Metabotropic glutamate receptor group III pathway PantherDB 1.551E-4 5.427E-4 1.978E-3 3.256E-3 2 64
7 213818 Glutamatergic synapse BioSystems: KEGG 4.927E-4 1.478E-3 5.389E-3 1.035E-2 2 114
8 1268785 Astrocytic Glutamate-Glutamine Uptake And Metabolism BioSystems: REACTOME 1.285E-3 2.998E-3 1.093E-2 2.698E-2 1 4
9 1268784 Neurotransmitter uptake and Metabolism In Glial Cells BioSystems: REACTOME 1.285E-3 2.998E-3 1.093E-2 2.698E-2 1 4
10 1268766 Transmission across Chemical Synapses BioSystems: REACTOME 1.789E-3 3.757E-3 1.370E-2 3.757E-2 2 218
11 1269917 Organic anion transporters BioSystems: REACTOME 3.209E-3 6.127E-3 2.234E-2
6.740E-2
 1 10
12 1268763 Neuronal System BioSystems: REACTOME 4.580E-3 7.772E-3 2.833E-2
9.618E-2
 2 351
13 PW:0000016 amyotrophic lateral sclerosis disease Pathway Ontology 4.811E-3 7.772E-3 2.833E-2
1.010E-1
 1 15
14 1269916 Amino acid transport across the plasma membrane BioSystems: REACTOME 9.924E-3 1.479E-2
5.390E-2
2.084E-1
 1 31
15 1268721 Sialic acid metabolism BioSystems: REACTOME 1.056E-2 1.479E-2
5.390E-2
2.218E-1
 1 33
16 83099 Amyotrophic lateral sclerosis (ALS) BioSystems: KEGG 1.629E-2 2.138E-2
7.793E-2
3.420E-1
 1 51
17 1268716 Synthesis of substrates in N-glycan biosythesis BioSystems: REACTOME 2.009E-2 2.482E-2
9.047E-2
4.219E-1
 1 63
18 1268715 Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein BioSystems: REACTOME 2.483E-2 2.897E-2
1.056E-1
5.214E-1
 1 78
19 172847 Protein digestion and absorption BioSystems: KEGG 2.861E-2 3.162E-2
1.153E-1
6.007E-1
 1 90
20 99052 Lysosome BioSystems: KEGG 3.894E-2 4.089E-2
1.491E-1
8.178E-1
 1 123
Show 15 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 570 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 7766664 Molecular cloning of two glutamate transporter subtypes from mouse brain. Pubmed 1.371E-8 2.344E-6 1.623E-5 7.815E-6 2 2
2 29303644 Expression of Glutamate Transporters in Mouse Liver, Kidney, and Intestine. Pubmed 1.371E-8 2.344E-6 1.623E-5 7.815E-6 2 2
3 12614333 The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures. Pubmed 1.371E-8 2.344E-6 1.623E-5 7.815E-6 2 2
4 16061389 Increased expression and function of glutamate transporters in multiple sclerosis. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
5 8733726 Dynamic changes in expression of glutamate transporter mRNAs in developing brain. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
6 20220082 Functional roles of high-affinity glutamate transporters in cochlear afferent synaptic transmission in the mouse. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
7 22215633 Specificity controls for immunocytochemistry: the antigen preadsorption test can lead to inaccurate assessment of antibody specificity. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
8 7521911 Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
9 17607354 The potential role of glutamate transporters in the pathogenesis of normal tension glaucoma. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
10 15135231 Distribution of glutamate transporters in the human placenta. Pubmed 4.113E-8 2.344E-6 1.623E-5 2.344E-5 2 3
11 15009636 Presenilin-1 and intracellular calcium stores regulate neuronal glutamate uptake. Pubmed 8.226E-8 3.126E-6 2.164E-5 4.689E-5 2 4
12 20410850 Analysis of 9p24 and 11p12-13 regions in autism spectrum disorders: rs1340513 in the JMJD2C gene is associated with ASDs in Finnish sample. Pubmed 8.226E-8 3.126E-6 2.164E-5 4.689E-5 2 4
13 9379843 Structure and functional expression of the cloned mouse neuronal high-affinity glutamate transporter. Pubmed 8.226E-8 3.126E-6 2.164E-5 4.689E-5 2 4
14 19364521 Protein kinase C-dependent trafficking of glutamate transporters excitatory amino acid carrier 1 and glutamate transporter 1b in cultured cerebellar granule cells. Pubmed 8.226E-8 3.126E-6 2.164E-5 4.689E-5 2 4
15 26690923 Caveolin-1 Sensitivity of Excitatory Amino Acid Transporters EAAT1, EAAT2, EAAT3, and EAAT4. Pubmed 8.226E-8 3.126E-6 2.164E-5 4.689E-5 2 4
16 9129177 Changes in expression and distribution of the glutamate transporter EAAT4 in developing mouse Purkinje cells. Pubmed 1.371E-7 4.884E-6 3.381E-5 7.814E-5 2 5
17 29350434 The cystine-glutamate exchanger (xCT, Slc7a11) is expressed in significant concentrations in a subpopulation of astrocytes in the mouse brain. Pubmed 2.056E-7 6.894E-6 4.774E-5 1.172E-4 2 6
18 16880397 From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development. Pubmed 1.069E-6 3.385E-5 2.343E-4 6.092E-4 2 13
19 19086053 Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment. Pubmed 4.790E-6 1.437E-4 9.950E-4 2.730E-3 3 301
20 24154525 Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Pubmed 7.399E-6 2.109E-4 1.460E-3 4.217E-3 3 348
21 24501781 Leukodystrophy Overview Pubmed 2.030E-5 2.241E-4 1.552E-3 1.157E-2 2 55
22 20398908 Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Pubmed 3.021E-5 2.241E-4 1.552E-3 1.722E-2 2 67
23 19156168 Pharmacogenetics of antipsychotic response in the CATIE trial: a candidate gene analysis. Pubmed 9.407E-5 2.241E-4 1.552E-3
5.362E-2
 2 118
24 12189496 Megalencephalic leukoencephalopathy with subcortical cysts; a founder effect in Israeli patients and a higher than expected carrier rate among Libyan Jews. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
25 22539860 The density of EAAC1 (EAAT3) glutamate transporters expressed by neurons in the mammalian CNS. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
26 14603469 The brain-specific protein MLC1 implicated in megalencephalic leukoencephalopathy with subcortical cysts is expressed in glial cells in the murine brain. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
27 23390085 No association between polymorphisms in the glutamate transporter SLC1A2 and Parkinson's disease. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
28 17991780 Transport direction determines the kinetics of substrate transport by the glutamate transporter EAAC1. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
29 29275184 Analysis of variant rs3794087 in SLC1A2 and Parkinson's disease in a Chinese Han population: A case-control study and meta-analysis. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
30 15265858 A trimeric quaternary structure is conserved in bacterial and human glutamate transporters. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
31 20301643 Free Sialic Acid Storage Disorders Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
32 12111645 A novel polymorphism in exon 11 of the WKL1 gene, shows no association with schizophrenia. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
33 23951268 SLC1A2 variant is associated with essential tremor in Taiwanese population. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
34 28049029 Glutamate transporter type 3 participates in maintaining morphine-induced conditioned place preference. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
35 26483543 The Hydroxyl Side Chain of a Highly Conserved Serine Residue Is Required for Cation Selectivity and Substrate Transport in the Glial Glutamate Transporter GLT-1/SLC1A2. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
36 12153483 Alternative splicing of the 5'-sequences of the mouse EAAT2 glutamate transporter and expression in a transgenic model for amyotrophic lateral sclerosis. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
37 21335552 The glial glutamate transporter 1 (GLT1) is expressed by pancreatic beta-cells and prevents glutamate-induced beta-cell death. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
38 16023578 Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
39 8020993 Assignment of the gene coding for the human high-affinity glutamate transporter EAAC1 to 9p24: potential role in dicarboxylic aminoaciduria and neurodegenerative disorders. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
40 26230766 Spermidine Ameliorates Neurodegeneration in a Mouse Model of Normal Tension Glaucoma. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
41 12605408 Differential regulation of 5' splice variants of the glutamate transporter EAAT2 in an in vivo model of chemical hypoxia induced by 3-nitropropionic acid. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
42 29920672 Ectopic positioning of Bergmann glia and impaired cerebellar wiring in Mlc1-over-expressing mice. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
43 22532568 Neutralizing aspartate 83 modifies substrate translocation of excitatory amino acid transporter 3 (EAAT3) glutamate transporters. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
44 23827345 Glutamate transporter type 3 mediates isoflurane preconditioning-induced acute phase of neuroprotection in mice. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
45 24797327 Isoflurane unveils a critical role of glutamate transporter type 3 in regulating hippocampal GluR1 trafficking and context-related learning and memory in mice. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
46 11698255 Role of glutamate transporters in the regulation of glutathione levels in human macrophages. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
47 26567011 Decreased glial and synaptic glutamate uptake in the striatum of HIV-1 gp120 transgenic mice. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
48 24162932 Changes in the expression of the glutamate transporter EAAT3/EAAC1 in health and disease. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
49 28771710 Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT-1 by a Notch-dependent mechanism. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
50 23596072 SLC1A2 variant associated with essential tremor but not Parkinson disease in Chinese subjects. Pubmed 1.309E-4 2.241E-4 1.552E-3
7.462E-2
 1 1
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 68 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:LGALS8 LGALS8 interactions 4.202E-4 2.362E-2
1.134E-1
 2.858E-2 2 116
2 int:ERVW-1 ERVW-1 interactions 8.471E-4 2.362E-2
1.134E-1
5.760E-2
 1 3
3 int:GGT5 GGT5 interactions 1.412E-3 2.362E-2
1.134E-1
9.599E-2
 1 5
4 int:SLC17A5 SLC17A5 interactions 1.412E-3 2.362E-2
1.134E-1
9.599E-2
 1 5
5 int:SLC1A4 SLC1A4 interactions 2.258E-3 2.362E-2
1.134E-1
1.535E-1
 1 8
6 int:DAPK2 DAPK2 interactions 2.822E-3 2.362E-2
1.134E-1
1.919E-1
 1 10
7 int:MLC1 MLC1 interactions 3.385E-3 2.362E-2
1.134E-1
2.302E-1
 1 12
8 int:ORMDL3 ORMDL3 interactions 3.667E-3 2.362E-2
1.134E-1
2.493E-1
 1 13
9 int:GOLGA7 GOLGA7 interactions 3.948E-3 2.362E-2
1.134E-1
2.685E-1
 1 14
10 int:KLK8 KLK8 interactions 4.511E-3 2.362E-2
1.134E-1
3.068E-1
 1 16
11 int:SLC1A2 SLC1A2 interactions 4.511E-3 2.362E-2
1.134E-1
3.068E-1
 1 16
12 int:LDLRAD1 LDLRAD1 interactions 4.793E-3 2.362E-2
1.134E-1
3.259E-1
 1 17
13 int:MYH3 MYH3 interactions 4.793E-3 2.362E-2
1.134E-1
3.259E-1
 1 17
14 int:MPC2 MPC2 interactions 5.074E-3 2.362E-2
1.134E-1
3.450E-1
 1 18
15 int:SBSN SBSN interactions 6.199E-3 2.362E-2
1.134E-1
4.215E-1
 1 22
16 int:PXMP2 PXMP2 interactions 6.199E-3 2.362E-2
1.134E-1
4.215E-1
 1 22
17 int:MYLK MYLK interactions 6.480E-3 2.362E-2
1.134E-1
4.406E-1
 1 23
18 int:NRN1 NRN1 interactions 6.480E-3 2.362E-2
1.134E-1
4.406E-1
 1 23
19 int:KCNJ10 KCNJ10 interactions 7.323E-3 2.362E-2
1.134E-1
4.979E-1
 1 26
20 int:CD320 CD320 interactions 7.884E-3 2.362E-2
1.134E-1
5.361E-1
 1 28
21 int:HACD2 HACD2 interactions 8.165E-3 2.362E-2
1.134E-1
5.552E-1
 1 29
22 int:DNAJC19 DNAJC19 interactions 8.445E-3 2.362E-2
1.134E-1
5.743E-1
 1 30
23 int:CHPT1 CHPT1 interactions 8.445E-3 2.362E-2
1.134E-1
5.743E-1
 1 30
24 int:MICU2 MICU2 interactions 8.445E-3 2.362E-2
1.134E-1
5.743E-1
 1 30
25 int:SLC25A17 SLC25A17 interactions 9.006E-3 2.362E-2
1.134E-1
6.124E-1
 1 32
26 int:FMC1 FMC1 interactions 9.567E-3 2.362E-2
1.134E-1
6.506E-1
 1 34
27 int:AJUBA AJUBA interactions 9.567E-3 2.362E-2
1.134E-1
6.506E-1
 1 34
28 int:CC2D1A CC2D1A interactions 1.013E-2 2.362E-2
1.134E-1
6.887E-1
 1 36
29 int:SLC1A1 SLC1A1 interactions 1.041E-2 2.362E-2
1.134E-1
7.077E-1
 1 37
30 int:SNX17 SNX17 interactions 1.069E-2 2.362E-2
1.134E-1
7.268E-1
 1 38
31 int:CST6 CST6 interactions 1.125E-2 2.362E-2
1.134E-1
7.649E-1
 1 40
32 int:MYCN MYCN interactions 1.125E-2 2.362E-2
1.134E-1
7.649E-1
 1 40
33 int:DTNA DTNA interactions 1.153E-2 2.362E-2
1.134E-1
7.839E-1
 1 41
34 int:NUMBL NUMBL interactions 1.181E-2 2.362E-2
1.134E-1
8.029E-1
 1 42
35 int:NDFIP1 NDFIP1 interactions 1.237E-2 2.376E-2
1.141E-1
8.410E-1
 1 44
36 int:DTNB DTNB interactions 1.293E-2 2.376E-2
1.141E-1
8.790E-1
 1 46
37 int:TPT1 TPT1 interactions 1.293E-2 2.376E-2
1.141E-1
8.790E-1
 1 46
38 int:APOOL APOOL interactions 1.349E-2 2.413E-2
1.159E-1
9.170E-1
 1 48
39 int:RNF5 RNF5 interactions 1.404E-2 2.449E-2
1.176E-1
9.550E-1
 1 50
40 int:EPHA4 EPHA4 interactions 1.488E-2 2.530E-2
1.215E-1
1.000E0
 1 53
41 int:CXCR4 CXCR4 interactions 1.544E-2 2.545E-2
1.223E-1
1.000E0
 1 55
42 int:ARL6IP5 ARL6IP5 interactions 1.572E-2 2.545E-2
1.223E-1
1.000E0
 1 56
43 int:TNFRSF10B TNFRSF10B interactions 1.990E-2 3.146E-2
1.511E-1
1.000E0
 1 71
44 int:SNX3 SNX3 interactions 2.406E-2 3.718E-2
1.786E-1
1.000E0
 1 86
45 int:SNTA1 SNTA1 interactions 2.544E-2 3.845E-2
1.847E-1
1.000E0
 1 91
46 int:RAB8A RAB8A interactions 2.738E-2 4.047E-2
1.944E-1
1.000E0
 1 98
47 int:SLC39A4 SLC39A4 interactions 2.848E-2 4.121E-2
1.980E-1
1.000E0
 1 102
48 int:SLAMF1 SLAMF1 interactions 3.096E-2 4.386E-2
2.107E-1
1.000E0
 1 111
49 int:INPPL1 INPPL1 interactions 3.179E-2 4.412E-2
2.119E-1
1.000E0
 1 114
50 int:PRMT6 PRMT6 interactions 3.454E-2 4.697E-2
2.257E-1
1.000E0
 1 124
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 2p15-p13 2p15-p13 2.885E-4 1.442E-3 3.294E-3 1.442E-3 1 2
2 11p13-p12 11p13-p12 8.653E-4 1.923E-3 4.390E-3 4.326E-3 1 6
3 9p24 9p24 1.154E-3 1.923E-3 4.390E-3 5.768E-3 1 8
4 6q13 6q13 5.614E-3 6.044E-3 1.380E-2 2.807E-2 1 39
5 22q13.33 22q13.33 6.044E-3 6.044E-3 1.380E-2 3.022E-2 1 42

11: Transcription Factor Binding Site [Display Chart] 3 input genes in category / 10 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 4 input genes in category / 1 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 752 Solute carriers genenames.org 2.189E-7 2.189E-7 2.189E-7 2.189E-7 4 395

13: Coexpression [Display Chart] 5 input genes in category / 503 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M2742 Genes up-regulated in hepatocellular carcinoma (HCC) induced by overexpression of MYC [GeneID=4609]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.323E-5 1.301E-2
8.845E-2
 2.677E-2 2 54
2 19061838-TableS12 Human Viral Cairo08 61genes GeneSigDB 6.361E-5 1.301E-2
8.845E-2
 3.200E-2 2 59
3 17284527-TableS1 Human Lypmhoma Leval07 644genes GeneSigDB 9.258E-5 1.301E-2
8.845E-2
 4.657E-2 3 492
4 11731795-SuppTable2 Human Lymphoma Armstrong02 100genes OverExpressed GeneSigDB 1.202E-4 1.301E-2
8.845E-2
6.048E-2
 2 81
5 20032505-TableS3 Human Leukemia Stam09 97genes GeneSigDB 1.293E-4 1.301E-2
8.845E-2
6.505E-2
 2 84
6 M9941 Genes down-regulated in B lymphocytes: wildtype versus MAP3K7 [GeneID=6885]. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 3.342E-2
2.272E-1
3.604E-1
 2 198
7 M6731 Genes down-regulated in spleen dendritic cells from healthy mice: 33D1+ versus DEC205+ subpopulations. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 3.342E-2
2.272E-1
3.604E-1
 2 198
8 M5844 Genes up-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus monocytes treated with 5000 ng/ml LPS (TLR4 agonist). MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 3.342E-2
2.272E-1
3.640E-1
 2 199
9 M6604 Genes up-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (180 min). MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.342E-2
2.272E-1
3.676E-1
 2 200
10 M5906 Genes defining early response to estrogen. MSigDB H: Hallmark Gene Sets (v6.0) 7.309E-4 3.342E-2
2.272E-1
3.676E-1
 2 200
11 M6067 Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus untreated (6h). MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.342E-2
2.272E-1
3.676E-1
 2 200
12 M16050 Upregulated in the vastus lateralis muscle of aged vs young adult rhesus monkeys MSigDB C2: CGP Curated Gene Sets (v6.0) 1.085E-3 4.547E-2
3.091E-1
5.456E-1
 2 244
Show 7 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 356 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Overall Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 6.208E-6 6.071E-4 3.918E-3 2.210E-3 3 188
2 Glioblastoma Single Cell Merged Astocyte Overall Top 200 Genes Glioblastoma Single Cell Merged Astocyte Overall Top 200 Genes 6.717E-6 6.071E-4 3.918E-3 2.391E-3 3 193
3 Glioblastoma Single Cell Merged Astocyte Top 200 Glioblastoma Single Cell Merged Astocyte Top 200 6.717E-6 6.071E-4 3.918E-3 2.391E-3 3 193
4 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/astrocyte Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/astrocyte Tabula Muris Consortium 6.822E-6 6.071E-4 3.918E-3 2.429E-3 3 194
5 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl2a Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl2a Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.737E-5 1.237E-3 7.983E-3 6.185E-3 3 265
6 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl2b Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl2b Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.054E-5 1.361E-3 8.782E-3 1.087E-2 3 320
7 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Subtype subAstrocyte.A.subGroup1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Subtype subAstrocyte.A.subGroup1 Top 200 Genes BrainMap 3.111E-5 1.361E-3 8.782E-3 1.108E-2 3 322
8 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl2c Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl2c Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.409E-5 1.361E-3 8.782E-3 1.213E-2 3 332
9 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl3 Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl3 Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.533E-5 1.361E-3 8.782E-3 1.258E-2 3 336
10 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl1 Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Subtype hRgl1 Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 3.823E-5 1.361E-3 8.782E-3 1.361E-2 3 345
11 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Top 200 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Top 200 BrainMap 6.631E-5 2.146E-3 1.385E-2 2.361E-2 3 415
12 BrainMap BrainAtlas - Human / Mouse Linnarsson Radial Glia-like Radial Glia-like Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Radial Glia-like Radial Glia-like Overall Top 200 Genes BrainMap 3.586E-4 9.189E-3
5.930E-2
1.277E-1
 2 132
13 BrainMap BrainAtlas - Human / Mouse Linnarsson Radial Glia-like Radial Glia-like Top 200 BrainMap BrainAtlas - Human / Mouse Linnarsson Radial Glia-like Radial Glia-like Top 200 BrainMap 3.586E-4 9.189E-3
5.930E-2
1.277E-1
 2 132
14 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/Bergmann glial cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/Bergmann glial cell Tabula Muris Consortium 5.262E-4 9.189E-3
5.930E-2
1.873E-1
 2 160
15 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.0.2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.0.2 Top 100 Genes 5.262E-4 9.189E-3
5.930E-2
1.873E-1
 2 160
16 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 6.506E-4 9.189E-3
5.930E-2
2.316E-1
 2 178
17 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup1 subAstrocyte.subGroup1 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup1 subAstrocyte.subGroup1 Overall Top 200 Genes BrainMap 6.875E-4 9.189E-3
5.930E-2
2.447E-1
 2 183
18 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup1 subAstrocyte.subGroup1 Top 200 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup1 subAstrocyte.subGroup1 Top 200 BrainMap 6.875E-4 9.189E-3
5.930E-2
2.447E-1
 2 183
19 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Overall Top 200 Genes BrainMap 7.101E-4 9.189E-3
5.930E-2
2.528E-1
 2 186
20 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb.Gja1 Astrocyte.astrocytes.Rorb.Gja1 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb.Gja1 Astrocyte.astrocytes.Rorb.Gja1 Overall Top 200 Genes BrainMap 7.101E-4 9.189E-3
5.930E-2
2.528E-1
 2 186
21 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A.Gja1 Astrocyte.astrocytes.A.Gja1 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A.Gja1 Astrocyte.astrocytes.A.Gja1 Overall Top 200 Genes BrainMap 7.101E-4 9.189E-3
5.930E-2
2.528E-1
 2 186
22 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb Astrocyte.astrocytes.Rorb Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb Astrocyte.astrocytes.Rorb Overall Top 200 Genes BrainMap 7.177E-4 9.189E-3
5.930E-2
2.555E-1
 2 187
23 BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Overall Top 200 Genes BrainMap 7.177E-4 9.189E-3
5.930E-2
2.555E-1
 2 187
24 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Overall Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Overall Top 200 Genes 7.177E-4 9.189E-3
5.930E-2
2.555E-1
 2 187
25 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Overall Top 200 Genes BrainMap 7.177E-4 9.189E-3
5.930E-2
2.555E-1
 2 187
26 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Astrocyte BrainMap 7.253E-4 9.189E-3
5.930E-2
2.582E-1
 2 188
27 BrainMap BrainAtlas - Human / Mouse Linnarsson Astrocyte Astrocyte Top 200 BrainMap BrainAtlas - Human / Mouse Linnarsson Astrocyte Astrocyte Top 200 BrainMap 7.330E-4 9.189E-3
5.930E-2
2.610E-1
 2 189
28 BrainMap BrainAtlas - Human / Mouse Linnarsson Astrocyte Astrocyte Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Astrocyte Astrocyte Overall Top 200 Genes BrainMap 7.330E-4 9.189E-3
5.930E-2
2.610E-1
 2 189
29 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/oligodendrocyte precursor cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/oligodendrocyte precursor cell Tabula Muris Consortium 7.485E-4 9.189E-3
5.930E-2
2.665E-1
 2 191
30 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Subtype astrocytes.A Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Subtype astrocytes.A Top 200 Genes 8.040E-4 9.233E-3
5.959E-2
2.862E-1
 2 198
31 BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Subtype Astrocyte.astrocytes.A Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Subtype Astrocyte.astrocytes.A Top 200 Genes BrainMap 8.040E-4 9.233E-3
5.959E-2
2.862E-1
 2 198
32 gudmap developingKidney e15.5 Proximal Tubules 1000 k4 DevelopingKidney e15.5 Proximal Tubules emap-28005 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 8.782E-4 9.657E-3
6.232E-2
3.127E-1
 2 207
33 Facebase RNAseq ratio e9.5 MandibularArch vs MaxillaryArch 1000 K5 FacebaseRNAseq ratio e9.5 MandibularArch vs MaxillaryArch top-relative-expression-ranked 1000 k-means-cluster#5 FaceBase_RNAseq 8.952E-4 9.657E-3
6.232E-2
3.187E-1
 2 209
34 Facebase RNAseq e8.5 Paraxial Mesoderm 1000 K1 FacebaseRNAseq e8.5 Paraxial Mesoderm top-relative-expression-ranked 1000 k-means-cluster#1 FaceBase_RNAseq 9.645E-4 1.010E-2
6.517E-2
3.434E-1
 2 217
35 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb Astrocyte.astrocytes.Rorb Subtype subAstrocyte.subGroup2 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb Astrocyte.astrocytes.Rorb Subtype subAstrocyte.subGroup2 Top 200 Genes BrainMap 1.120E-3 1.139E-2
7.353E-2
3.988E-1
 2 234
36 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb.Gja1 Astrocyte.astrocytes.Rorb.Gja1 Subtype Astrocyte.astrocytes.Rorb.Gja1.Myoc Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb.Gja1 Astrocyte.astrocytes.Rorb.Gja1 Subtype Astrocyte.astrocytes.Rorb.Gja1.Myoc Top 200 Genes BrainMap 1.338E-3 1.288E-2
8.311E-2
4.765E-1
 2 256
37 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb.Gja1 Astrocyte.astrocytes.Rorb.Gja1 Top 200 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb.Gja1 Astrocyte.astrocytes.Rorb.Gja1 Top 200 BrainMap 1.338E-3 1.288E-2
8.311E-2
4.765E-1
 2 256
38 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Subtype astrocytes.Rorb Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Subtype astrocytes.Rorb Top 200 Genes 1.412E-3 1.289E-2
8.317E-2
5.026E-1
 2 263
39 BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Subtype Astrocyte.astrocytes.Rorb Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Subtype Astrocyte.astrocytes.Rorb Top 200 Genes BrainMap 1.412E-3 1.289E-2
8.317E-2
5.026E-1
 2 263
40 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 PosteriorCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 PosteriorCortex Top 200 Genes BrainMap 1.465E-3 1.298E-2
8.375E-2
5.217E-1
 2 268
41 BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Top 200 BrainMap BrainAtlas - Mouse McCarroll Astrocyte Astrocyte Top 200 BrainMap 1.531E-3 1.298E-2
8.375E-2
5.451E-1
 2 274
42 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Top 200 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Astrocyte Top 200 1.531E-3 1.298E-2
8.375E-2
5.451E-1
 2 274
43 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Subtype subAstrocyte.subGroup3 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A Astrocyte.astrocytes.A Subtype subAstrocyte.subGroup3 Top 200 Genes BrainMap 1.701E-3 1.409E-2
9.090E-2
6.057E-1
 2 289
44 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 FrontalCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 FrontalCortex Top 200 Genes BrainMap 1.868E-3 1.497E-2
9.662E-2
6.650E-1
 2 303
45 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb Astrocyte.astrocytes.Rorb Subtype subAstrocyte.Rorb.subGroup1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.Rorb Astrocyte.astrocytes.Rorb Subtype subAstrocyte.Rorb.subGroup1 Top 200 Genes BrainMap 1.892E-3 1.497E-2
9.662E-2
6.737E-1
 2 305
46 BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A.Gja1 Astrocyte.astrocytes.A.Gja1 Subtype Astrocyte.astrocytes.A.Gja1.Myoc Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Astrocyte.astrocytes.A.Gja1 Astrocyte.astrocytes.A.Gja1 Subtype Astrocyte.astrocytes.A.Gja1.Myoc Top 200 Genes BrainMap 2.055E-3 1.567E-2
1.011E-1
7.316E-1
 2 318
47 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte. .Trf Oligodendrocyte. .Trf Subtype Oligodendrocyte. .Trf.Ndrg2 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte. .Trf Oligodendrocyte. .Trf Subtype Oligodendrocyte. .Trf.Ndrg2 Top 200 Genes BrainMap 2.119E-3 1.567E-2
1.011E-1
7.545E-1
 2 323
48 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/PosteriorCortex/PosteriorCortex/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/PosteriorCortex/PosteriorCortex/Astrocyte BrainMap 2.289E-3 1.567E-2
1.011E-1
8.148E-1
 1 10
49 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Thalamus/Thalamus/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Thalamus/Thalamus/Astrocyte BrainMap 2.289E-3 1.567E-2
1.011E-1
8.148E-1
 1 10
50 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex/FrontalCortex/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex/FrontalCortex/Astrocyte BrainMap 2.289E-3 1.567E-2
1.011E-1
8.148E-1
 1 10
Show 45 more annotations

15: Computational [Display Chart] 3 input genes in category / 19 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 5 input genes in category / 183 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-500a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.985E-5 6.747E-3 3.906E-2 7.293E-3 2 145
2 hsa-miR-1827:PITA hsa-miR-1827:PITA TOP PITA 1.291E-4 6.747E-3 3.906E-2 2.363E-2 2 261
3 hsa-miR-940:PITA hsa-miR-940:PITA TOP PITA 1.464E-4 6.747E-3 3.906E-2 2.680E-2 2 278
4 GTGCCAA,MIR-96:MSigDB GTGCCAA,MIR-96:MSigDB MSigDB 1.517E-4 6.747E-3 3.906E-2 2.777E-2 2 283
5 hsa-miR-1259:PITA hsa-miR-1259:PITA TOP PITA 1.843E-4 6.747E-3 3.906E-2 3.373E-2 2 312
6 hsa-miR-4800-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.144E-3 3.133E-2
1.814E-1
3.923E-1
 1 31
7 hsa-miR-3619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.144E-3 3.133E-2
1.814E-1
3.923E-1
 1 31
8 hsa-miR-4776-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.351E-3 3.133E-2
1.814E-1
4.302E-1
 1 34
9 hsa-miR-652-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.904E-3 3.133E-2
1.814E-1
5.314E-1
 1 42
10 hsa-miR-3138:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.249E-3 3.133E-2
1.814E-1
5.945E-1
 1 47
11 hsa-miR-1284:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 3.133E-2
1.814E-1
6.198E-1
 1 49
12 hsa-miR-4641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.594E-3 3.133E-2
1.814E-1
6.577E-1
 1 52
13 hsa-miR-758-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.008E-3 3.133E-2
1.814E-1
7.335E-1
 1 58
14 hsa-miR-4743-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 3.133E-2
1.814E-1
7.461E-1
 1 59
15 hsa-miR-1910-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 3.133E-2
1.814E-1
7.461E-1
 1 59
16 hsa-miR-6866-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 3.133E-2
1.814E-1
7.966E-1
 1 63
17 hsa-miR-6776-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 3.133E-2
1.814E-1
7.966E-1
 1 63
18 hsa-miR-325:PITA hsa-miR-325:PITA TOP PITA 4.491E-3 3.133E-2
1.814E-1
8.218E-1
 1 65
19 hsa-miR-6744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.698E-3 3.133E-2
1.814E-1
8.597E-1
 1 68
20 hsa-miR-7974:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.698E-3 3.133E-2
1.814E-1
8.597E-1
 1 68
21 hsa-miR-5586-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.905E-3 3.133E-2
1.814E-1
8.975E-1
 1 71
22 hsa-miR-7114-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.042E-3 3.133E-2
1.814E-1
9.228E-1
 1 73
23 hsa-miR-323a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 3.133E-2
1.814E-1
9.480E-1
 1 75
24 hsa-miR-541:PITA hsa-miR-541:PITA TOP PITA 5.387E-3 3.133E-2
1.814E-1
9.858E-1
 1 78
25 hsa-miR-15a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.456E-3 3.133E-2
1.814E-1
9.985E-1
 1 79
26 hsa-miR-654-5p:PITA hsa-miR-654-5p:PITA TOP PITA 5.525E-3 3.133E-2
1.814E-1
1.000E0
 1 80
27 hsa-miR-633:Functional MTI Functional MTI miRTarbase 5.594E-3 3.133E-2
1.814E-1
1.000E0
 1 81
28 hsa-miR-4255:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.732E-3 3.133E-2
1.814E-1
1.000E0
 1 83
29 hsa-miR-3922-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.420E-3 3.133E-2
1.814E-1
1.000E0
 1 93
30 hsa-miR-934:PITA hsa-miR-934:PITA TOP PITA 6.696E-3 3.133E-2
1.814E-1
1.000E0
 1 97
31 hsa-miR-4801:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.765E-3 3.133E-2
1.814E-1
1.000E0
 1 98
32 hsa-miR-4731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 3.133E-2
1.814E-1
1.000E0
 1 99
33 hsa-miR-448:Functional MTI Functional MTI miRTarbase 6.833E-3 3.133E-2
1.814E-1
1.000E0
 1 99
34 hsa-miR-497-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.971E-3 3.133E-2
1.814E-1
1.000E0
 1 101
35 hsa-miR-1255a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.040E-3 3.133E-2
1.814E-1
1.000E0
 1 102
36 hsa-miR-1255b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.040E-3 3.133E-2
1.814E-1
1.000E0
 1 102
37 TCCAGAT,MIR-516-5P:MSigDB TCCAGAT,MIR-516-5P:MSigDB MSigDB 7.109E-3 3.133E-2
1.814E-1
1.000E0
 1 103
38 hsa-miR-3176:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.315E-3 3.133E-2
1.814E-1
1.000E0
 1 106
39 ATCATGA,MIR-433:MSigDB ATCATGA,MIR-433:MSigDB MSigDB 7.315E-3 3.133E-2
1.814E-1
1.000E0
 1 106
40 hsa-miR-564:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.659E-3 3.133E-2
1.814E-1
1.000E0
 1 111
41 hsa-miR-6787-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.759E-3 3.133E-2
1.814E-1
1.000E0
 1 127
42 hsa-miR-4328:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.828E-3 3.133E-2
1.814E-1
1.000E0
 1 128
43 hsa-miR-1324:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.034E-3 3.133E-2
1.814E-1
1.000E0
 1 131
44 hsa-miR-671-5p:PITA hsa-miR-671-5p:PITA TOP PITA 9.034E-3 3.133E-2
1.814E-1
1.000E0
 1 131
45 hsa-miR-1245:PITA hsa-miR-1245:PITA TOP PITA 9.103E-3 3.133E-2
1.814E-1
1.000E0
 1 132
46 hsa-miR-1908-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.309E-3 3.133E-2
1.814E-1
1.000E0
 1 135
47 hsa-miR-383:PITA hsa-miR-383:PITA TOP PITA 9.447E-3 3.133E-2
1.814E-1
1.000E0
 1 137
48 hsa-miR-6835-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.515E-3 3.133E-2
1.814E-1
1.000E0
 1 138
49 hsa-miR-632:PITA hsa-miR-632:PITA TOP PITA 9.584E-3 3.133E-2
1.814E-1
1.000E0
 1 139
50 hsa-miR-1237-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.927E-3 3.133E-2
1.814E-1
1.000E0
 1 144
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 2417 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000007627 p-MB Stitch 1.471E-8 2.730E-5 2.285E-4 3.555E-5 3 27
2 CID000075725 alpha-(methylamino)isobutyric acid Stitch 2.259E-8 2.730E-5 2.285E-4 5.461E-5 3 31
3 CID004133412 benzyloxyaspartate Stitch 3.904E-8 3.145E-5 2.632E-4 9.436E-5 3 37
4 CID000000236 asparagine Stitch 1.176E-7 7.105E-5 5.945E-4 2.842E-4 3 53
5 CID009547990 YVN Stitch 2.300E-7 1.106E-4 9.251E-4 5.559E-4 2 4
6 CID000025701 cysteic acid Stitch 2.744E-7 1.106E-4 9.251E-4 6.633E-4 3 70
7 CID000001650 AC1L1BXF Stitch 4.947E-7 1.708E-4 1.429E-3 1.196E-3 3 85
8 CID000001182 DL-valine Stitch 9.377E-7 2.833E-4 2.371E-3 2.266E-3 3 105
9 CID000127037 2,3-PDCA Stitch 1.073E-6 2.881E-4 2.411E-3 2.593E-3 2 8
10 CID000000205 allo-threonine Stitch 1.368E-6 3.307E-4 2.768E-3 3.307E-3 3 119
11 CID000000876 methionine Stitch 2.431E-6 5.343E-4 4.471E-3 5.877E-3 3 144
12 CID000125748 anthglutin Stitch 2.987E-6 6.017E-4 5.035E-3 7.221E-3 2 13
13 CID000000750 glycine Stitch 3.936E-6 6.491E-4 5.431E-3 9.514E-3 3 169
14 CID003906779 Ro106-9920 Stitch 4.021E-6 6.491E-4 5.431E-3 9.718E-3 2 15
15 CID000004053 sarcolysin Stitch 4.150E-6 6.491E-4 5.431E-3 1.003E-2 3 172
16 ctd:D014639 Vanadium CTD 4.297E-6 6.491E-4 5.431E-3 1.039E-2 3 174
17 3900 UP Ergocryptine-alpha [511-09-1]; Up 200; 7uM; MCF7; HT HG-U133A Broad Institute CMAP Up 5.958E-6 8.181E-4 6.846E-3 1.440E-2 3 194
18 6607 DN Benzthiazide [91-33-8]; Down 200; 9.2uM; PC3; HT HG-U133A Broad Institute CMAP Down 6.239E-6 8.181E-4 6.846E-3 1.508E-2 3 197
19 1516 UP Loxapine succinate [27833-64-3]; Up 200; 9uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.431E-6 8.181E-4 6.846E-3 1.554E-2 3 199
20 CID000000617 DL-Serine Stitch 6.827E-6 8.186E-4 6.849E-3 1.650E-2 3 203
21 CID000015553 clopyralid Stitch 7.273E-6 8.186E-4 6.849E-3 1.758E-2 2 20
22 CID000000867 malonate Stitch 7.451E-6 8.186E-4 6.849E-3 1.801E-2 3 209
23 CID000002397 bisindolylmaleimide II Stitch 1.446E-5 1.519E-3 1.271E-2 3.495E-2 2 28
24 CID000000602 alanine Stitch 1.587E-5 1.599E-3 1.338E-2 3.837E-2 3 269
25 CID000065137 His-pro-dkp Stitch 1.778E-5 1.719E-3 1.439E-2 4.298E-2 2 31
26 ctd:C520612 N-methyl-N-(6-methoxy-1-phenyl-1,2,3,4-tetrahydronaphthalen-2-ylmethyl)aminomethylcarboxylic acid CTD 2.274E-5 2.036E-3 1.704E-2
5.497E-2
 2 35
27 CID000011711 ethyldichloroarsine Stitch 2.274E-5 2.036E-3 1.704E-2
5.497E-2
 2 35
28 CID000060803 sipatrigine Stitch 2.545E-5 2.197E-3 1.839E-2
6.152E-2
 2 37
29 CID000003614 tele-methylhistamine Stitch 2.687E-5 2.239E-3 1.874E-2
6.494E-2
 2 38
30 ctd:D018683 Excitatory Amino Acid Agents CTD 2.832E-5 2.281E-3 1.909E-2
6.844E-2
 2 39
31 CID000444260 fm P Stitch 2.980E-5 2.295E-3 1.920E-2
7.204E-2
 2 40
32 CID000022128 L-alanosine Stitch 3.133E-5 2.295E-3 1.920E-2
7.572E-2
 2 41
33 CID000125017 desvenlafaxine Stitch 3.133E-5 2.295E-3 1.920E-2
7.572E-2
 2 41
34 CID000002170 amoxapine Stitch 3.953E-5 2.810E-3 2.351E-2
9.553E-2
 2 46
35 CID000005425 beta-hydroxyaspartic acid Stitch 4.128E-5 2.851E-3 2.385E-2
9.977E-2
 2 47
36 CID000001271 L-CCG-I Stitch 4.677E-5 3.140E-3 2.627E-2
1.130E-1
 2 50
37 CID000002656 AC1L1E65 Stitch 5.061E-5 3.306E-3 2.767E-2
1.223E-1
 2 52
38 CID000004368 W-A-Y Stitch 5.876E-5 3.679E-3 3.079E-2
1.420E-1
 2 56
39 CID000065270 cysteinylglycine Stitch 6.089E-5 3.679E-3 3.079E-2
1.472E-1
 2 57
40 CID000010457 suberate Stitch 6.089E-5 3.679E-3 3.079E-2
1.472E-1
 2 57
41 ctd:C070417 Win 55212-2 CTD 6.306E-5 3.718E-3 3.111E-2
1.524E-1
 2 58
42 CID000000364 diaminopropionic acid Stitch 6.980E-5 3.923E-3 3.283E-2
1.687E-1
 2 61
43 CID000003868 pyrrolidine-2,4-dicarboxylate Stitch 6.980E-5 3.923E-3 3.283E-2
1.687E-1
 2 61
44 CID000000738 glutamin Stitch 7.925E-5 4.354E-3 3.643E-2
1.916E-1
 3 461
45 CID000004515 NO-711 Stitch 8.177E-5 4.392E-3 3.675E-2
1.976E-1
 2 66
46 CID000115114 DCG-IV Stitch 8.683E-5 4.465E-3 3.736E-2
2.099E-1
 2 68
47 DB00142 L-Glutamic Acid Drug Bank 8.683E-5 4.465E-3 3.736E-2
2.099E-1
 2 68
48 CID000003172 N-(2-chloroethyl)-N-ethyl-2-bromobenzylamine Stitch 8.941E-5 4.502E-3 3.767E-2
2.161E-1
 2 69
49 CID000115127 ponasterone A Stitch 9.203E-5 4.540E-3 3.799E-2
2.224E-1
 2 70
50 CID000444055 AC1L9FMM Stitch 1.001E-4 4.654E-3 3.894E-2
2.420E-1
 2 73
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 233 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0028968 Olivopontocerebellar Atrophies DisGeNET Curated 1.444E-5 3.364E-3 2.029E-2 3.364E-3 2 20
2 C0027765 nervous system disorder DisGeNET Curated 1.698E-4 4.493E-3 2.710E-2 3.957E-2 3 423
3 C0023891 Liver Cirrhosis, Alcoholic DisGeNET Curated 2.039E-4 4.493E-3 2.710E-2 4.751E-2 2 74
4 C2931872 Free sialic acid storage disease DisGeNET BeFree 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
5 C1096902 Infantile Sialic Acid Storage Disease DisGeNET Curated 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
6 cv:C1096903 Salla disease Clinical Variations 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
7 C1857253 Dicarboxylicaminoaciduria DisGeNET Curated 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
8 C4225254 SPASTIC TETRAPLEGIA, THIN CORPUS CALLOSUM, AND PROGRESSIVE MICROCEPHALY DisGeNET Curated 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
9 OMIN:604369 SIALURIA, FINNISH TYPE OMIM 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
10 C0265113 Progressing stroke DisGeNET BeFree 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
11 C1963905 Infantile free sialic acid storage disease DisGeNET Curated 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
12 C1858855 Diffuse swelling of cerebral white matter DisGeNET Curated 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
13 cv:C1096902 Sialic acid storage disease, severe infantile type Clinical Variations 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
14 C1858857 Diffuse spongiform leukoencephalopathy DisGeNET Curated 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
15 OMIN:269920 INFANTILE SIALIC ACID STORAGE DISORDER OMIM 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
16 cv:CN169674 Schizophrenia 18 Clinical Variations 3.085E-4 4.493E-3 2.710E-2
7.189E-2
 1 1
17 C4020860 Supratentorial atrophy DisGeNET Curated 3.292E-4 4.511E-3 2.721E-2
7.669E-2
 2 94
18 C0154671 Degenerative brain disorder DisGeNET Curated 4.344E-4 5.622E-3 3.391E-2
1.012E-1
 2 108
19 C0239182 Watery diarrhea DisGeNET BeFree 6.170E-4 6.535E-3 3.941E-2
1.438E-1
 1 2
20 cv:CN176898 Megalencephalic leukoencephalopathy with subcortical cysts Clinical Variations 6.170E-4 6.535E-3 3.941E-2
1.438E-1
 1 2
21 cv:C1858854 Megalencephalic leukoencephalopathy with subcortical cysts 1 Clinical Variations 6.170E-4 6.535E-3 3.941E-2
1.438E-1
 1 2
22 OMIN:604004 MEGALENCEPHALIC LEUKOENCEPHALOPATHY WITH SUBCORTICAL CYSTS; MLC OMIM 6.170E-4 6.535E-3 3.941E-2
1.438E-1
 1 2
23 C0014556 Epilepsy, Temporal Lobe DisGeNET Curated 6.480E-4 6.565E-3 3.959E-2
1.510E-1
 2 132
24 C2129214 Loose stool DisGeNET BeFree 1.850E-3 1.473E-2
8.885E-2
4.311E-1
 1 6
25 C0009241 Cognition Disorders DisGeNET Curated 2.035E-3 1.473E-2
8.885E-2
4.741E-1
 2 235
26 C0029421 Osteochondritis Dissecans DisGeNET Curated 2.158E-3 1.473E-2
8.885E-2
5.029E-1
 1 7
27 C1854718 J-shaped sella turcica DisGeNET Curated 2.158E-3 1.473E-2
8.885E-2
5.029E-1
 1 7
28 C4072841 J-shaped hypophysial fossa DisGeNET Curated 2.158E-3 1.473E-2
8.885E-2
5.029E-1
 1 7
29 C4072842 Omega shaped hypophysial fossa DisGeNET Curated 2.158E-3 1.473E-2
8.885E-2
5.029E-1
 1 7
30 C0026838 Muscle Spasticity DisGeNET Curated 2.317E-3 1.473E-2
8.885E-2
5.399E-1
 2 251
31 C0235946 Cerebral atrophy DisGeNET Curated 2.335E-3 1.473E-2
8.885E-2
5.441E-1
 2 252
32 C0751213 Tactile Allodynia DisGeNET BeFree 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
33 C0748607 Recurrent seizures DisGeNET BeFree 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
34 C1836855 Vacuolated lymphocytes DisGeNET Curated 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
35 C0233697 Obsessions DisGeNET BeFree 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
36 C0036344 Schizophrenia, Catatonic DisGeNET Curated 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
37 C1849221 Fair hair DisGeNET Curated 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
38 C0239801 Blonde hair DisGeNET Curated 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
39 C1858854 MEGALENCEPHALIC LEUKOENCEPHALOPATHY WITH SUBCORTICAL CYSTS DisGeNET Curated 2.466E-3 1.473E-2
8.885E-2
5.746E-1
 1 8
40 C0026552 Morphine Dependence DisGeNET Curated 2.774E-3 1.528E-2
9.214E-2
6.464E-1
 1 9
41 C0007398 Catatonia DisGeNET Curated 2.774E-3 1.528E-2
9.214E-2
6.464E-1
 1 9
42 C0543918 SCHIZOPHRENIA 10 DisGeNET BeFree 3.082E-3 1.528E-2
9.214E-2
7.181E-1
 1 10
43 C0424290 Compulsive hoarding DisGeNET Curated 3.082E-3 1.528E-2
9.214E-2
7.181E-1
 1 10
44 C0522254 Analgesic Overuse Headache DisGeNET BeFree 3.082E-3 1.528E-2
9.214E-2
7.181E-1
 1 10
45 C0333641 Atrophic DisGeNET Curated 3.082E-3 1.528E-2
9.214E-2
7.181E-1
 1 10
46 C0085593 Chills DisGeNET Curated 3.082E-3 1.528E-2
9.214E-2
7.181E-1
 1 10
47 C0023529 Leukomalacia, Periventricular DisGeNET Curated 3.082E-3 1.528E-2
9.214E-2
7.181E-1
 1 10
48 C0342853 Sialuria DisGeNET Curated 3.390E-3 1.645E-2
9.923E-2
7.898E-1
 1 11
49 C0033975 Psychotic Disorders DisGeNET Curated 3.534E-3 1.680E-2
1.013E-1
8.233E-1
 2 311
50 C3541517 ECTODERMAL DYSPLASIA 11A, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL DOMINANT DisGeNET Curated 4.005E-3 1.830E-2
1.103E-1
9.332E-1
 1 13
Show 45 more annotations