Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc96_9, positive side

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1: GO: Molecular Function [Display Chart] 9 input genes in category / 75 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001631 cysteinyl leukotriene receptor activity 6.202E-7 4.651E-5 2.280E-4 4.651E-5 2 3
2 GO:0004974 leukotriene receptor activity 2.066E-6 7.748E-5 3.798E-4 1.550E-4 2 5
3 GO:0004953 icosanoid receptor activity 2.473E-5 6.181E-4 3.030E-3 1.854E-3 2 16
4 GO:0005506 iron ion binding 5.097E-5 9.557E-4 4.684E-3 3.823E-3 3 161
5 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen 7.212E-5 9.707E-4 4.758E-3 5.409E-3 2 27
6 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen 7.765E-5 9.707E-4 4.758E-3 5.824E-3 2 28
7 GO:0052869 arachidonic acid omega-hydroxylase activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
8 GO:0018747 phenanthrene-1,2-epoxide hydrolase activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
9 GO:0018746 phenanthrene-3,4-epoxide hydrolase activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
10 GO:0018742 epoxide hydrolase B activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
11 GO:0008096 juvenile hormone epoxide hydrolase activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
12 GO:0018743 phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
13 GO:0018863 phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
14 GO:0034926 pyrene-4,5-epoxide hydrolase activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
15 GO:0018745 epoxide hydrolase A activity 4.823E-4 2.411E-3 1.182E-2 3.617E-2 1 1
16 GO:0051213 dioxygenase activity 8.101E-4 3.145E-3 1.541E-2
6.076E-2
2 90
17 GO:0019119 phenanthrene-9,10-epoxide hydrolase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
18 GO:0047977 hepoxilin-epoxide hydrolase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
19 GO:0019118 phenanthrene-epoxide hydrolase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
20 GO:0004051 arachidonate 5-lipoxygenase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
21 GO:0097258 20-hydroxy-leukotriene B4 omega oxidase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
22 GO:0016165 linoleate 13S-lipoxygenase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
23 GO:0097259 20-aldehyde-leukotriene B4 20-monooxygenase activity 9.644E-4 3.145E-3 1.541E-2
7.233E-2
1 2
24 GO:0052871 alpha-tocopherol omega-hydroxylase activity 1.446E-3 3.740E-3 1.833E-2
1.085E-1
1 3
25 GO:0004464 leukotriene-C4 synthase activity 1.446E-3 3.740E-3 1.833E-2
1.085E-1
1 3
26 GO:0004052 arachidonate 12-lipoxygenase activity 1.446E-3 3.740E-3 1.833E-2
1.085E-1
1 3
27 GO:0019767 IgE receptor activity 1.446E-3 3.740E-3 1.833E-2
1.085E-1
1 3
28 GO:0051120 hepoxilin A3 synthase activity 1.446E-3 3.740E-3 1.833E-2
1.085E-1
1 3
29 GO:0052870 tocopherol omega-hydroxylase activity 1.446E-3 3.740E-3 1.833E-2
1.085E-1
1 3
30 GO:0008528 G protein-coupled peptide receptor activity 1.730E-3 4.326E-3 2.120E-2
1.298E-1
2 132
31 GO:0001653 peptide receptor activity 1.809E-3 4.377E-3 2.145E-2
1.357E-1
2 135
32 GO:0050051 leukotriene-B4 20-monooxygenase activity 1.928E-3 4.519E-3 2.215E-2
1.446E-1
1 4
33 GO:0018685 alkane 1-monooxygenase activity 2.409E-3 5.315E-3 2.605E-2
1.807E-1
1 5
34 GO:0019863 IgE binding 2.409E-3 5.315E-3 2.605E-2
1.807E-1
1 5
35 GO:0004301 epoxide hydrolase activity 2.891E-3 6.194E-3 3.036E-2
2.168E-1
1 6
36 GO:0019763 immunoglobulin receptor activity 3.853E-3 7.604E-3 3.727E-2
2.889E-1
1 8
37 GO:0052872 tocotrienol omega-hydroxylase activity 3.853E-3 7.604E-3 3.727E-2
2.889E-1
1 8
38 GO:0016803 ether hydrolase activity 3.853E-3 7.604E-3 3.727E-2
2.889E-1
1 8
39 GO:0047498 calcium-dependent phospholipase A2 activity 4.333E-3 8.333E-3 4.084E-2
3.250E-1
1 9
40 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen 4.814E-3 9.025E-3 4.424E-2
3.610E-1
1 10
41 GO:0008970 phospholipase A1 activity 5.294E-3 9.233E-3 4.526E-2
3.970E-1
1 11
42 GO:0016801 hydrolase activity, acting on ether bonds 5.294E-3 9.233E-3 4.526E-2
3.970E-1
1 11
43 GO:0016846 carbon-sulfur lyase activity 5.294E-3 9.233E-3 4.526E-2
3.970E-1
1 11
44 GO:0008392 arachidonic acid epoxygenase activity 7.213E-3 1.176E-2
5.764E-2
5.409E-1
1 15
45 GO:0043295 glutathione binding 7.213E-3 1.176E-2
5.764E-2
5.409E-1
1 15
46 GO:0008391 arachidonic acid monooxygenase activity 7.213E-3 1.176E-2
5.764E-2
5.409E-1
1 15
47 GO:1900750 oligopeptide binding 7.692E-3 1.227E-2
6.016E-2
5.769E-1
1 16
48 GO:0004602 glutathione peroxidase activity 9.607E-3 1.501E-2
7.357E-2
7.205E-1
1 20
49 GO:0004622 lysophospholipase activity 1.104E-2 1.690E-2
8.283E-2
8.280E-1
1 23
50 GO:0019865 immunoglobulin binding 1.152E-2 1.728E-2
8.468E-2
8.639E-1
1 24
Show 45 more annotations

2: GO: Biological Process [Display Chart] 9 input genes in category / 494 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006691 leukotriene metabolic process 1.595E-12 3.175E-10 2.153E-9 7.879E-10 5 33
2 GO:1901568 fatty acid derivative metabolic process 1.928E-12 3.175E-10 2.153E-9 9.524E-10 6 102
3 GO:0006690 icosanoid metabolic process 1.928E-12 3.175E-10 2.153E-9 9.524E-10 6 102
4 GO:0033559 unsaturated fatty acid metabolic process 4.022E-12 4.967E-10 3.368E-9 1.987E-9 6 115
5 GO:0046456 icosanoid biosynthetic process 1.278E-11 1.052E-9 7.133E-9 6.312E-9 5 49
6 GO:1901570 fatty acid derivative biosynthetic process 1.278E-11 1.052E-9 7.133E-9 6.312E-9 5 49
7 GO:0006636 unsaturated fatty acid biosynthetic process 4.326E-11 3.053E-9 2.070E-8 2.137E-8 5 62
8 GO:2001300 lipoxin metabolic process 1.560E-9 9.632E-8 6.531E-7 7.705E-7 3 6
9 GO:0006633 fatty acid biosynthetic process 3.397E-9 1.864E-7 1.264E-6 1.678E-6 5 146
10 GO:0006631 fatty acid metabolic process 5.449E-9 2.692E-7 1.825E-6 2.692E-6 6 379
11 GO:0019369 arachidonic acid metabolic process 6.222E-9 2.794E-7 1.895E-6 3.073E-6 4 51
12 GO:0019372 lipoxygenase pathway 2.227E-8 9.167E-7 6.216E-6 1.100E-5 3 13
13 GO:0072330 monocarboxylic acid biosynthetic process 2.432E-8 9.240E-7 6.266E-6 1.201E-5 5 216
14 GO:0001676 long-chain fatty acid metabolic process 6.029E-8 2.127E-6 1.443E-5 2.978E-5 4 89
15 GO:0019370 leukotriene biosynthetic process 8.861E-8 2.918E-6 1.979E-5 4.377E-5 3 20
16 GO:0046394 carboxylic acid biosynthetic process 1.599E-7 4.646E-6 3.150E-5 7.898E-5 5 315
17 GO:0016053 organic acid biosynthetic process 1.599E-7 4.646E-6 3.150E-5 7.898E-5 5 315
18 GO:0061737 leukotriene signaling pathway 3.111E-6 8.538E-5 5.790E-4 1.537E-3 2 6
19 GO:1903524 positive regulation of blood circulation 1.827E-5 4.750E-4 3.221E-3 9.025E-3 3 114
20 GO:0045766 positive regulation of angiogenesis 2.899E-5 7.160E-4 4.855E-3 1.432E-2 3 133
21 GO:1904018 positive regulation of vasculature development 4.070E-5 9.575E-4 6.492E-3 2.011E-2 3 149
22 GO:0002526 acute inflammatory response 4.940E-5 1.109E-3 7.522E-3 2.440E-2 3 159
23 GO:0050880 regulation of blood vessel size 6.573E-5 1.376E-3 9.330E-3 3.247E-2 3 175
24 GO:0035150 regulation of tube size 6.685E-5 1.376E-3 9.330E-3 3.302E-2 3 176
25 GO:0003018 vascular process in circulatory system 1.007E-4 1.989E-3 1.349E-2 4.972E-2 3 202
26 GO:0007584 response to nutrient 1.114E-4 2.116E-3 1.435E-2
5.501E-2
3 209
27 GO:0002675 positive regulation of acute inflammatory response 1.225E-4 2.242E-3 1.520E-2
6.052E-2
2 35
28 GO:0032309 icosanoid secretion 1.604E-4 2.821E-3 1.913E-2
7.924E-2
2 40
29 GO:0045765 regulation of angiogenesis 1.656E-4 2.821E-3 1.913E-2
8.181E-2
3 239
30 GO:0045907 positive regulation of vasoconstriction 1.943E-4 3.000E-3 2.034E-2
9.601E-2
2 44
31 GO:1901571 fatty acid derivative transport 1.943E-4 3.000E-3 2.034E-2
9.601E-2
2 44
32 GO:0071715 icosanoid transport 1.943E-4 3.000E-3 2.034E-2
9.601E-2
2 44
33 GO:1901342 regulation of vasculature development 2.221E-4 3.325E-3 2.255E-2
1.097E-1
3 264
34 GO:0002437 inflammatory response to antigenic stimulus 3.384E-4 4.917E-3 3.334E-2
1.672E-1
2 58
35 GO:0050891 multicellular organismal water homeostasis 4.382E-4 5.684E-3 3.854E-2
2.165E-1
2 66
36 GO:1903522 regulation of blood circulation 4.432E-4 5.684E-3 3.854E-2
2.190E-1
3 334
37 GO:1901751 leukotriene A4 metabolic process 4.833E-4 5.684E-3 3.854E-2
2.387E-1
1 1
38 GO:0031407 oxylipin metabolic process 4.833E-4 5.684E-3 3.854E-2
2.387E-1
1 1
39 GO:2001306 lipoxin B4 biosynthetic process 4.833E-4 5.684E-3 3.854E-2
2.387E-1
1 1
40 GO:0097176 epoxide metabolic process 4.833E-4 5.684E-3 3.854E-2
2.387E-1
1 1
41 GO:2001304 lipoxin B4 metabolic process 4.833E-4 5.684E-3 3.854E-2
2.387E-1
1 1
42 GO:0071299 cellular response to vitamin A 4.833E-4 5.684E-3 3.854E-2
2.387E-1
1 1
43 GO:0030104 water homeostasis 6.274E-4 7.144E-3 4.844E-2
3.099E-1
2 79
44 GO:0048871 multicellular organismal homeostasis 6.363E-4 7.144E-3 4.844E-2
3.143E-1
3 378
45 GO:0019229 regulation of vasoconstriction 6.595E-4 7.240E-3 4.909E-2
3.258E-1
2 81
46 GO:0002673 regulation of acute inflammatory response 6.923E-4 7.435E-3
5.041E-2
3.420E-1
2 83
47 GO:0015908 fatty acid transport 8.314E-4 8.375E-3
5.679E-2
4.107E-1
2 91
48 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 8.868E-4 8.375E-3
5.679E-2
4.381E-1
2 94
49 GO:0042377 vitamin K catabolic process 9.663E-4 8.375E-3
5.679E-2
4.774E-1
1 2
50 GO:2001303 lipoxin A4 biosynthetic process 9.663E-4 8.375E-3
5.679E-2
4.774E-1
1 2
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 9 input genes in category / 17 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0042383 sarcolemma 2.192E-3 3.727E-2
1.282E-1
3.727E-2 2 152
2 GO:0005641 nuclear envelope lumen 5.653E-3 3.993E-2
1.374E-1
9.610E-2
1 12
3 GO:0031965 nuclear membrane 7.739E-3 3.993E-2
1.374E-1
1.316E-1
2 290
4 GO:0042588 zymogen granule 1.128E-2 3.993E-2
1.374E-1
1.917E-1
1 24
5 GO:0005640 nuclear outer membrane 1.174E-2 3.993E-2
1.374E-1
1.997E-1
1 25

4: Human Phenotype [Display Chart] 4 input genes in category / 50 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0005229 Jejunoileal ulceration 8.498E-4 2.545E-2
1.145E-1
4.249E-2 1 1
2 HP:0030800 Abnormal visual accommodation 3.396E-3 2.545E-2
1.145E-1
1.698E-1
1 4
3 HP:0012055 Ciliary body melanoma 3.396E-3 2.545E-2
1.145E-1
1.698E-1
1 4
4 HP:0008494 Inferior lens subluxation 3.396E-3 2.545E-2
1.145E-1
1.698E-1
1 4
5 HP:0012054 Choroidal melanoma 3.396E-3 2.545E-2
1.145E-1
1.698E-1
1 4
6 HP:0005265 Abnormality of the jejunum 3.396E-3 2.545E-2
1.145E-1
1.698E-1
1 4
7 HP:0030786 Photopsia 4.244E-3 2.545E-2
1.145E-1
2.122E-1
1 5
8 HP:0012776 Abnormal ciliary body morphology 4.244E-3 2.545E-2
1.145E-1
2.122E-1
1 5
9 HP:0011524 Iris melanoma 5.091E-3 2.545E-2
1.145E-1
2.545E-1
1 6
10 HP:0200026 Ocular pain 5.091E-3 2.545E-2
1.145E-1
2.545E-1
1 6
11 HP:0011499 Mydriasis 5.937E-3 2.699E-2
1.214E-1
2.969E-1
1 7
12 HP:0012508 Metamorphopsia 8.474E-3 3.531E-2
1.589E-1
4.237E-1
1 10
13 HP:0001132 Lens subluxation 1.016E-2 3.908E-2
1.758E-1
5.081E-1
1 12
14 HP:0007716 Uveal melanoma 1.185E-2 4.229E-2
1.903E-1
5.924E-1
1 14
15 HP:0007906 Ocular hypertension 1.353E-2 4.229E-2
1.903E-1
6.766E-1
1 16
16 HP:0012632 Abnormal intraocular pressure 1.353E-2 4.229E-2
1.903E-1
6.766E-1
1 16
Show 11 more annotations

5: Mouse Phenotype [Display Chart] 9 input genes in category / 167 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0002531 abnormal type I hypersensitivity reaction 1.341E-11 2.239E-9 1.276E-8 2.239E-9 6 79
2 MP:0002148 abnormal hypersensitivity reaction 1.845E-9 1.541E-7 8.780E-7 3.082E-7 6 177
3 MP:0005597 decreased susceptibility to type I hypersensitivity reaction 1.917E-8 1.067E-6 6.081E-6 3.202E-6 4 38
4 MP:0002498 abnormal acute inflammation 8.793E-8 3.671E-6 2.092E-5 1.468E-5 6 337
5 MP:0009817 decreased leukotriene level 6.706E-6 2.240E-4 1.276E-3 1.120E-3 2 5
6 MP:0009813 abnormal leukotriene level 1.006E-5 2.799E-4 1.595E-3 1.679E-3 2 6
7 MP:0005087 decreased acute inflammation 1.486E-5 3.545E-4 2.020E-3 2.481E-3 4 197
8 MP:0001619 abnormal vascular permeability 3.216E-5 6.713E-4 3.825E-3 5.371E-3 3 77
9 MP:0001876 decreased inflammatory response 6.524E-5 1.211E-3 6.898E-3 1.089E-2 4 287
10 MP:0003071 decreased vascular permeability 1.020E-4 1.704E-3 9.707E-3 1.704E-2 2 18
11 MP:0001844 autoimmune response 2.832E-4 3.920E-3 2.234E-2 4.729E-2 4 419
12 MP:0005005 abnormal self tolerance 2.884E-4 3.920E-3 2.234E-2 4.816E-2 4 421
13 MP:0005000 abnormal immune tolerance 3.101E-4 3.920E-3 2.234E-2
5.178E-2
4 429
14 MP:0009811 abnormal prostaglandin level 3.286E-4 3.920E-3 2.234E-2
5.488E-2
2 32
15 MP:0005596 increased susceptibility to type I hypersensitivity reaction 5.411E-4 6.024E-3 3.433E-2
9.036E-2
2 41
16 MP:0002462 abnormal granulocyte physiology 1.201E-3 1.254E-2
7.145E-2
2.006E-1
3 262
17 MP:0002423 abnormal mast cell physiology 1.485E-3 1.459E-2
8.312E-2
2.480E-1
2 68
18 MP:0005501 abnormal skin physiology 3.066E-3 2.844E-2
1.621E-1
5.120E-1
3 363
19 MP:0003423 reduced thrombolysis 3.473E-3 3.052E-2
1.739E-1
5.799E-1
1 4
20 MP:0003033 abnormal pulmonary vascular resistance 4.339E-3 3.623E-2
2.065E-1
7.246E-1
1 5
21 MP:0000249 abnormal blood vessel physiology 4.666E-3 3.711E-2
2.115E-1
7.793E-1
3 421
22 MP:0004822 decreased susceptibility to experimental autoimmune uveoretinitis 5.205E-3 3.779E-2
2.153E-1
8.692E-1
1 6
23 MP:0012010 parturition failure 5.205E-3 3.779E-2
2.153E-1
8.692E-1
1 6
24 MP:0009818 abnormal thromboxane level 6.934E-3 4.626E-2
2.636E-1
1.000E0
1 8
25 MP:0003422 abnormal thrombolysis 6.934E-3 4.626E-2
2.636E-1
1.000E0
1 8
26 MP:0005088 increased acute inflammation 7.202E-3 4.626E-2
2.636E-1
1.000E0
2 152
27 MP:0020408 altered susceptibility to induced thrombosis 7.798E-3 4.651E-2
2.650E-1
1.000E0
1 9
28 MP:0010936 decreased airway resistance 7.798E-3 4.651E-2
2.650E-1
1.000E0
1 9
29 MP:0005462 abnormal mast cell differentiation 8.661E-3 4.988E-2
2.842E-1
1.000E0
1 10
Show 24 more annotations

6: Domain [Display Chart] 9 input genes in category / 54 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR004071 Cyst leuk rcpt InterPro 2.051E-7 1.108E-5 5.068E-5 1.108E-5 2 2
2 PF00305 Lipoxygenase Pfam 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
3 PS51393 LIPOXYGENASE 3 PROSITE 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
4 IPR013819 LipOase C InterPro 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
5 PS00081 LIPOXYGENASE 2 PROSITE 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
6 IPR000907 LipOase InterPro 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
7 IPR020834 LipOase CS InterPro 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
8 IPR020833 LipOase Fe BS InterPro 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
9 IPR001885 LipOase mml InterPro 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
10 PS00711 LIPOXYGENASE 1 PROSITE 3.074E-6 1.660E-5 7.595E-5 1.660E-4 2 6
11 SM00308 LH2 SMART 3.126E-5 1.535E-4 7.022E-4 1.688E-3 2 18
12 2.60.60.20 - Gene3D 4.288E-5 1.544E-4 7.062E-4 2.315E-3 2 21
13 IPR001024 PLAT/LH2 dom InterPro 4.288E-5 1.544E-4 7.062E-4 2.315E-3 2 21
14 PS50095 PLAT PROSITE 4.288E-5 1.544E-4 7.062E-4 2.315E-3 2 21
15 PF01477 PLAT Pfam 4.288E-5 1.544E-4 7.062E-4 2.315E-3 2 21
16 IPR013311 CLT2 recept InterPro 4.804E-4 1.526E-3 6.982E-3 2.594E-2 1 1
17 IPR013310 CLT1 recept InterPro 4.804E-4 1.526E-3 6.982E-3 2.594E-2 1 1
18 IPR001446 5 LipOase AP InterPro 1.441E-3 3.889E-3 1.780E-2
7.779E-2
1 3
19 IPR018295 FLAP/GST2/LTC4S CS InterPro 1.441E-3 3.889E-3 1.780E-2
7.779E-2
1 3
20 PS01297 FLAP GST2 LTC4S PROSITE 1.441E-3 3.889E-3 1.780E-2
7.779E-2
1 3
21 IPR001129 Membr-assoc MAPEG InterPro 2.879E-3 6.477E-3 2.963E-2
1.555E-1
1 6
22 PF01124 MAPEG Pfam 2.879E-3 6.477E-3 2.963E-2
1.555E-1
1 6
23 1.20.120.550 - Gene3D 3.358E-3 6.477E-3 2.963E-2
1.814E-1
1 7
24 IPR023352 MAPEG-like dom InterPro 3.358E-3 6.477E-3 2.963E-2
1.814E-1
1 7
25 IPR002642 LysoPLipase cat dom InterPro 3.358E-3 6.477E-3 2.963E-2
1.814E-1
1 7
26 PS51210 PLA2C PROSITE 3.358E-3 6.477E-3 2.963E-2
1.814E-1
1 7
27 PF01735 PLA2 B Pfam 3.358E-3 6.477E-3 2.963E-2
1.814E-1
1 7
28 SM00022 PLAc SMART 3.358E-3 6.477E-3 2.963E-2
1.814E-1
1 7
29 PS51263 ADF H PROSITE 4.795E-3 8.091E-3 3.702E-2
2.589E-1
1 10
30 SM00102 ADF SMART 4.795E-3 8.091E-3 3.702E-2
2.589E-1
1 10
31 IPR002108 ADF-H InterPro 4.795E-3 8.091E-3 3.702E-2
2.589E-1
1 10
32 PF00241 Cofilin ADF Pfam 4.795E-3 8.091E-3 3.702E-2
2.589E-1
1 10
33 IPR016035 Acyl Trfase/lysoPLipase InterPro 8.139E-3 1.332E-2
6.093E-2
4.395E-1
1 17
34 3.40.20.10 - Gene3D 1.147E-2 1.770E-2
8.099E-2
6.195E-1
1 24
35 IPR029006 ADF-H/Gelsolin-like dom InterPro 1.147E-2 1.770E-2
8.099E-2
6.195E-1
1 24
36 IPR002401 Cyt P450 E grp-I InterPro 2.142E-2 3.212E-2
1.470E-1
1.000E0
1 45
37 IPR017972 Cyt P450 CS InterPro 2.518E-2 3.675E-2
1.681E-1
1.000E0
1 53
38 PS00086 CYTOCHROME P450 PROSITE 2.706E-2 3.716E-2
1.700E-1
1.000E0
1 57
39 PF00067 p450 Pfam 2.753E-2 3.716E-2
1.700E-1
1.000E0
1 58
40 1.10.630.10 - Gene3D 2.753E-2 3.716E-2
1.700E-1
1.000E0
1 58
41 IPR001128 Cyt P450 InterPro 2.846E-2 3.749E-2
1.715E-1
1.000E0
1 60
42 PF13895 Ig 2 Pfam 3.453E-2 4.440E-2
2.032E-1
1.000E0
1 73
Show 37 more annotations

7: Pathway [Display Chart] 9 input genes in category / 98 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1270087 Arachidonic acid metabolism BioSystems: REACTOME 2.965E-10 1.580E-8 8.163E-8 2.905E-8 5 61
2 82991 Arachidonic acid metabolism BioSystems: KEGG 3.224E-10 1.580E-8 8.163E-8 3.159E-8 5 62
3 MAP00590 Prostaglandin and leukotriene metabolism MAP00590 Prostaglandin and leukotriene metabolism GenMAPP 4.857E-10 1.587E-8 8.199E-8 4.760E-8 4 19
4 1270093 Synthesis of Lipoxins (LX) BioSystems: REACTOME 5.219E-9 1.279E-7 6.607E-7 5.115E-7 3 6
5 PW:0000462 lipoxygenase mediated of arachidonic acid metabolism Pathway Ontology 1.460E-8 2.862E-7 1.479E-6 1.431E-6 3 8
6 1270089 Synthesis of Leukotrienes (LT) and Eoxins (EX) BioSystems: REACTOME 5.247E-7 8.571E-6 4.429E-5 5.142E-5 3 24
7 835386 lipoxin biosynthesis BioSystems: BIOCYC 1.393E-6 1.950E-5 1.008E-4 1.365E-4 2 3
8 PW:0000464 leukotriene metabolic Pathway Ontology 2.785E-6 3.412E-5 1.763E-4 2.729E-4 2 4
9 545300 leukotriene biosynthesis BioSystems: BIOCYC 4.640E-6 4.547E-5 2.350E-4 4.547E-4 2 5
10 1269562 Leukotriene receptors BioSystems: REACTOME 4.640E-6 4.547E-5 2.350E-4 4.547E-4 2 5
11 137958 Endothelins BioSystems: Pathway Interaction Database 6.010E-6 5.354E-5 2.767E-4 5.890E-4 3 53
12 83082 Fc epsilon RI signaling pathway BioSystems: KEGG 1.279E-5 1.044E-4 5.396E-4 1.253E-3 3 68
13 1270090 Synthesis of 5-eicosatetraenoic acids BioSystems: REACTOME 1.668E-5 1.257E-4 6.497E-4 1.635E-3 2 9
14 1269560 Eicosanoid ligand-binding receptors BioSystems: REACTOME 4.854E-5 3.398E-4 1.756E-3 4.757E-3 2 15
15 525336 Serotonergic synapse BioSystems: KEGG 5.877E-5 3.840E-4 1.984E-3 5.760E-3 3 113
16 PW:0000485 eicosanoids metabolic Pathway Ontology 7.065E-5 4.327E-4 2.236E-3 6.924E-3 2 18
17 SMP00075 Arachidonic Acid Metabolism SMPDB 8.767E-5 5.054E-4 2.611E-3 8.592E-3 2 20
18 M1908 Fc Epsilon Receptor I Signaling in Mast Cells MSigDB C2 BIOCARTA (v6.0) 3.395E-4 1.848E-3 9.551E-3 3.327E-2 2 39
19 790011 Ovarian steroidogenesis BioSystems: KEGG 5.589E-4 2.883E-3 1.490E-2
5.477E-2
2 50
20 1270094 Synthesis of Hepoxilins (HX) and Trioxilins (TrX) BioSystems: REACTOME 7.229E-4 3.220E-3 1.664E-2
7.084E-2
1 1
21 SMP00353 Leukotriene C4 Synthesis Deficiency SMPDB 7.229E-4 3.220E-3 1.664E-2
7.084E-2
1 1
22 545365 alpha-tocopherol degradation BioSystems: BIOCYC 7.229E-4 3.220E-3 1.664E-2
7.084E-2
1 1
23 138050 Fc-epsilon receptor I signaling in mast cells BioSystems: Pathway Interaction Database 7.780E-4 3.315E-3 1.713E-2
7.625E-2
2 59
24 782387 aspirin-triggered lipoxin biosynthesis BioSystems: BIOCYC 1.445E-3 5.059E-3 2.614E-2
1.416E-1
1 2
25 782384 resolvin D biosynthesis BioSystems: BIOCYC 1.445E-3 5.059E-3 2.614E-2
1.416E-1
1 2
26 1269589 phospho-PLA2 pathway BioSystems: REACTOME 1.445E-3 5.059E-3 2.614E-2
1.416E-1
1 2
27 782385 aspirin triggered resolvin D biosynthesis BioSystems: BIOCYC 1.445E-3 5.059E-3 2.614E-2
1.416E-1
1 2
28 782386 aspirin triggered resolvin E biosynthesis BioSystems: BIOCYC 1.445E-3 5.059E-3 2.614E-2
1.416E-1
1 2
29 948277 Inflammatory mediator regulation of TRP channels BioSystems: KEGG 2.087E-3 7.053E-3 3.645E-2
2.045E-1
2 97
30 1270071 Acyl chain remodeling of CL BioSystems: REACTOME 4.330E-3 1.369E-2
7.074E-2
4.244E-1
1 6
31 1270092 Synthesis of 12-eicosatetraenoic acid derivatives BioSystems: REACTOME 4.330E-3 1.369E-2
7.074E-2
4.244E-1
1 6
32 1311074 Phospholipase D signaling pathway BioSystems: KEGG 4.659E-3 1.427E-2
7.372E-2
4.565E-1
2 146
33 1270063 Hydrolysis of LPC BioSystems: REACTOME 5.770E-3 1.663E-2
8.594E-2
5.655E-1
1 8
34 SMP00102 Bromfenac Pathway SMPDB 5.770E-3 1.663E-2
8.594E-2
5.655E-1
1 8
35 1270095 Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) BioSystems: REACTOME 6.489E-3 1.817E-2
9.389E-2
6.360E-1
1 9
36 83050 Calcium signaling pathway BioSystems: KEGG 7.152E-3 1.947E-2
1.006E-1
7.009E-1
2 182
37 P00031 Inflammation mediated by chemokine and cytokine signaling pathway PantherDB 7.852E-3 2.045E-2
1.057E-1
7.695E-1
2 191
38 1269578 G alpha (q) signalling events BioSystems: REACTOME 7.932E-3 2.045E-2
1.057E-1
7.773E-1
2 192
39 1270198 Eicosanoids BioSystems: REACTOME 8.644E-3 2.172E-2
1.122E-1
8.471E-1
1 12
40 1270200 Miscellaneous substrates BioSystems: REACTOME 1.008E-2 2.469E-2
1.276E-1
9.877E-1
1 14
41 1269348 Platelet sensitization by LDL BioSystems: REACTOME 1.223E-2 2.786E-2
1.440E-1
1.000E0
1 17
42 1270067 Acyl chain remodelling of PI BioSystems: REACTOME 1.223E-2 2.786E-2
1.440E-1
1.000E0
1 17
43 1270197 Fatty acids BioSystems: REACTOME 1.223E-2 2.786E-2
1.440E-1
1.000E0
1 17
44 1270069 Acyl chain remodelling of PG BioSystems: REACTOME 1.294E-2 2.882E-2
1.489E-1
1.000E0
1 18
45 M8731 Aspirin Blocks Signaling Pathway Involved in Platelet Activation MSigDB C2 BIOCARTA (v6.0) 1.580E-2 3.362E-2
1.737E-1
1.000E0
1 22
46 1270065 Acyl chain remodelling of PS BioSystems: REACTOME 1.580E-2 3.362E-2
1.737E-1
1.000E0
1 22
47 83053 Neuroactive ligand-receptor interaction BioSystems: KEGG 1.613E-2 3.362E-2
1.737E-1
1.000E0
2 278
48 1269354 ADP signalling through P2Y purinoceptor 1 BioSystems: REACTOME 1.793E-2 3.587E-2
1.853E-1
1.000E0
1 25
49 82993 alpha-Linolenic acid metabolism BioSystems: KEGG 1.793E-2 3.587E-2
1.853E-1
1.000E0
1 25
50 1270062 Acyl chain remodelling of PC BioSystems: REACTOME 1.936E-2 3.794E-2
1.960E-1
1.000E0
1 27
Show 45 more annotations

8: Pubmed [Display Chart] 9 input genes in category / 1572 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19450127 Asthma pharmacogenetic study using finite mixture models to handle drug-response heterogeneity. Pubmed 2.344E-17 3.685E-14 2.925E-13 3.685E-14 5 9
2 17460547 Pharmacogenetics of the 5-lipoxygenase biosynthetic pathway and variable clinical response to montelukast. Pubmed 4.688E-17 3.685E-14 2.925E-13 7.369E-14 5 10
3 18366797 Influence of leukotriene gene polymorphisms on chronic rhinosinusitis. Pubmed 7.106E-15 3.724E-12 2.956E-11 1.117E-11 4 5
4 20219953 Cysteinyl-leukotriene type 1 receptors transduce a critical signal for the up-regulation of eosinophilopoiesis by interleukin-13 and eotaxin in murine bone marrow. Pubmed 2.132E-14 8.377E-12 6.650E-11 3.351E-11 4 6
5 19131661 Genetic variation in the leukotriene pathway and carotid intima-media thickness: a 2-stage replication study. Pubmed 9.946E-14 3.127E-11 2.482E-10 1.563E-10 4 8
6 16920908 Cutting edge: Interleukin 4-dependent mast cell proliferation requires autocrine/intracrine cysteinyl leukotriene-induced signaling. Pubmed 9.047E-12 2.370E-9 1.882E-8 1.422E-8 3 3
7 22416124 Eosinophil-derived leukotriene C4 signals via type 2 cysteinyl leukotriene receptor to promote skin fibrosis in a mouse model of atopic dermatitis. Pubmed 3.618E-11 8.126E-9 6.450E-8 5.688E-8 3 4
8 14749922 Leukotriene-related gene polymorphisms in ASA-intolerant asthma: an association with a haplotype of 5-lipoxygenase. Pubmed 9.045E-11 1.185E-8 9.405E-8 1.422E-7 3 5
9 16293801 Influence of leukotriene pathway polymorphisms on response to montelukast in asthma. Pubmed 9.045E-11 1.185E-8 9.405E-8 1.422E-7 3 5
10 17924829 CysLTR1 promoter polymorphism and requirement for leukotriene receptor antagonist in aspirin-intolerant asthma patients. Pubmed 9.045E-11 1.185E-8 9.405E-8 1.422E-7 3 5
11 19524426 Leukotriene pathway polymorphisms are associated with altered cysteinyl leukotriene production in children with acute asthma. Pubmed 9.045E-11 1.185E-8 9.405E-8 1.422E-7 3 5
12 19214143 5-lipoxygenase pharmacogenetics in asthma: overlap with Cys-leukotriene receptor antagonist loci. Pubmed 9.045E-11 1.185E-8 9.405E-8 1.422E-7 3 5
13 23828562 Lack of effect of common single nucleotide polymorphisms in leukotriene pathway genes on platelet reactivity in patients with diabetes. Pubmed 1.809E-10 2.031E-8 1.612E-7 2.843E-7 3 6
14 21307302 5-Lipoxygenase metabolite 4-HDHA is a mediator of the antiangiogenic effect of Ï?-3 polyunsaturated fatty acids. Pubmed 1.809E-10 2.031E-8 1.612E-7 2.843E-7 3 6
15 28011865 Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. Pubmed 3.165E-10 3.317E-8 2.633E-7 4.975E-7 3 7
16 19807693 Coactosin-like protein functions as a stabilizing chaperone for 5-lipoxygenase: role of tryptophan 102. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
17 27115897 Expression of CysLTR1 and 2 in Maturating Lymphocytes of Hyperplasic Tonsils Compared to Peripheral Cells in Children. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
18 19579006 Hyperforin is a novel type of 5-lipoxygenase inhibitor with high efficacy in vivo. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
19 12751768 The leukotriene receptor CysLT1 and 5-lipoxygenase are upregulated in colon cancer. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
20 17693579 CysLT2 receptors interact with CysLT1 receptors and down-modulate cysteinyl leukotriene dependent mitogenic responses of mast cells. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
21 14532840 Expression of lipoxygenase in human bladder carcinoma and growth inhibition by its inhibitors. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
22 21436586 Mouse and human neutrophils induce anaphylaxis. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
23 12100046 Expression and localization of the cysteinyl leukotriene 1 receptor in human nasal mucosa. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
24 11854273 Characterization of mouse cysteinyl leukotriene receptors mCysLT1 and mCysLT2: differential pharmacological properties and tissue distribution. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
25 18276782 Endothelial cysteinyl leukotriene 2 receptor expression mediates myocardial ischemia-reperfusion injury. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
26 21357742 Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
27 27221082 Expression of cysteinyl leukotriene receptor 1 and 2 (CysLTR1 and CysLTR2) in the lymphocytes of hyperplastic tonsils: comparison between allergic and nonallergic snoring children. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
28 19080797 Analysis of 927T > C CYSLTR1 and -444A > C LTC4S polymorphisms in children with asthma. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
29 18931305 Functional recognition of a distinct receptor preferential for leukotriene E4 in mice lacking the cysteinyl leukotriene 1 and 2 receptors. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
30 14767568 Relationship between lipoxygenase and human testicular cancer. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
31 21729626 [Association of leukotriene gene polymorphisms with response to antileukotriene treatment in patients with asthma]. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
32 16924104 Coactosin-like protein supports 5-lipoxygenase enzyme activity and up-regulates leukotriene A4 production. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
33 20433311 Functional expression of cysteinyl leukotriene receptors on human platelets. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
34 25760841 [Expression of CysLTR-1 and CysLTR-2 in adenoid tissues from children with adenoid hypertrophy]. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
35 17153879 Analysis of 927T> C CYSLTRI and -444A > C LTC4S polymorphisms in patients with asthma. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
36 11696047 Levels of cysteinyl leukotriene receptor mRNA in human peripheral leucocytes: significantly higher expression of cysteinyl leukotriene receptor 2 mRNA in eosinophils. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
37 16771777 Determination of structure and transcriptional regulation of CYSLTR1 and an association study with asthma and rhinitis. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
38 25477712 Roles of 5-lipoxygenase and cysteinyl-leukotriene type 1 receptors in the hematological response to allergen challenge and its prevention by diethylcarbamazine in a murine model of asthma. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
39 17941281 Agonist- and T(H)2 cytokine-induced up-regulation of cysteinyl leukotriene receptor messenger RNA in human monocytes. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
40 17236225 Common polymorphisms in 5-lipoxygenase and 12-lipoxygenase genes and the risk of incident, sporadic colorectal adenoma. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
41 23002438 Cysteinyl leukotriene 2 receptor on dendritic cells negatively regulates ligand-dependent allergic pulmonary inflammation. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
42 15696087 Expression of the cysteinyl leukotriene receptors cysLT(1) and cysLT(2) in aspirin-sensitive and aspirin-tolerant chronic rhinosinusitis. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
43 20696828 Arachidonic acid metabolism regulates Escherichia coli penetration of the blood-brain barrier. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
44 14970333 Cysteinyl leukotriene 1 receptor controls the severity of chronic pulmonary inflammation and fibrosis. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
45 17883728 Responsiveness to montelukast is associated with bronchial hyperresponsiveness and total immunoglobulin E but not polymorphisms in the leukotriene C4 synthase and cysteinyl leukotriene receptor 1 genes in Korean children with exercise-induced asthma (EIA). Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
46 15010818 Expression of lipoxygenase in human prostate cancer and growth reduction by its inhibitors. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
47 22634478 Increased cysteinyl leukotriene concentration and receptor expression in tonsillar tissues of Chinese children with sleep-disordered breathing. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
48 20724598 Different roles of 12/15-lipoxygenase in diabetic large and small fiber peripheral and autonomic neuropathies. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
49 16756959 Distinct roles of CysLT1 and CysLT2 receptors in oxygen glucose deprivation-induced PC12 cell death. Pubmed 4.936E-8 1.584E-6 1.257E-5 7.759E-5 2 2
50 16081317 The 5-lipoxygenase pathway in arterial wall biology and atherosclerosis. Pubmed 1.481E-7 3.233E-6 2.566E-5 2.328E-4 2 3
Show 45 more annotations

9: Interaction [Display Chart] 9 input genes in category / 138 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CYSLTR2 CYSLTR2 interactions 2.298E-7 3.171E-5 1.746E-4 3.171E-5 2 2
2 int:CYSLTR1 CYSLTR1 interactions 6.891E-7 4.755E-5 2.619E-4 9.509E-5 2 3
3 int:LTC4S LTC4S interactions 1.378E-6 6.338E-5 3.491E-4 1.901E-4 2 4
4 int:ALOX5AP ALOX5AP interactions 2.296E-6 7.920E-5 4.363E-4 3.168E-4 2 5
5 int:ALOX5 ALOX5 interactions 3.064E-6 8.458E-5 4.659E-4 4.229E-4 3 60
6 int:ALOX12 ALOX12 interactions 1.032E-5 2.373E-4 1.307E-3 1.424E-3 2 10
7 int:COTL1 COTL1 interactions 7.420E-5 1.463E-3 8.057E-3 1.024E-2 2 26
8 int:PLA2G4A PLA2G4A interactions 2.351E-4 4.055E-3 2.233E-2 3.244E-2 2 46
9 int:PLA2G5 PLA2G5 interactions 1.017E-3 1.403E-2
7.727E-2
1.403E-1
1 2
10 int:HHIPL2 HHIPL2 interactions 1.017E-3 1.403E-2
7.727E-2
1.403E-1
1 2
11 int:PDR PDR interactions 1.524E-3 1.913E-2
1.053E-1
2.104E-1
1 3
12 int:GPR17 GPR17 interactions 2.032E-3 2.157E-2
1.188E-1
2.804E-1
1 4
13 int:CYP4F2 CYP4F2 interactions 2.032E-3 2.157E-2
1.188E-1
2.804E-1
1 4
14 int:PDE6H PDE6H interactions 3.047E-3 2.335E-2
1.286E-1
4.205E-1
1 6
15 int:PDXDC2P-NPIPB14P PDXDC2P-NPIPB14P interactions 3.047E-3 2.335E-2
1.286E-1
4.205E-1
1 6
16 int:GSAP GSAP interactions 3.047E-3 2.335E-2
1.286E-1
4.205E-1
1 6
17 int:RUNDC1 RUNDC1 interactions 3.554E-3 2.335E-2
1.286E-1
4.904E-1
1 7
18 int:NEU3 NEU3 interactions 3.554E-3 2.335E-2
1.286E-1
4.904E-1
1 7
19 int:XAGE1B XAGE1B interactions 3.554E-3 2.335E-2
1.286E-1
4.904E-1
1 7
20 int:FCER1A FCER1A interactions 3.554E-3 2.335E-2
1.286E-1
4.904E-1
1 7
21 int:CYP4F12 CYP4F12 interactions 3.554E-3 2.335E-2
1.286E-1
4.904E-1
1 7
22 int:ARMCX5 ARMCX5 interactions 4.061E-3 2.335E-2
1.286E-1
5.604E-1
1 8
23 int:IL17RD IL17RD interactions 4.061E-3 2.335E-2
1.286E-1
5.604E-1
1 8
24 int:MND1 MND1 interactions 4.061E-3 2.335E-2
1.286E-1
5.604E-1
1 8
25 int:HEBP1 HEBP1 interactions 5.074E-3 2.801E-2
1.543E-1
7.002E-1
1 10
26 int:MGST1 MGST1 interactions 5.580E-3 2.962E-2
1.631E-1
7.700E-1
1 11
27 int:ALPL ALPL interactions 6.086E-3 2.999E-2
1.652E-1
8.398E-1
1 12
28 int:KIF16B KIF16B interactions 6.086E-3 2.999E-2
1.652E-1
8.398E-1
1 12
29 int:FCER1G FCER1G interactions 6.591E-3 3.136E-2
1.728E-1
9.096E-1
1 13
30 int:KAT5 KAT5 interactions 7.066E-3 3.159E-2
1.740E-1
9.751E-1
2 257
31 int:MS4A2 MS4A2 interactions 7.097E-3 3.159E-2
1.740E-1
9.793E-1
1 14
32 int:LSS LSS interactions 8.107E-3 3.390E-2
1.867E-1
1.000E0
1 16
33 int:DDHD2 DDHD2 interactions 8.107E-3 3.390E-2
1.867E-1
1.000E0
1 16
34 int:SH3BGRL SH3BGRL interactions 8.611E-3 3.395E-2
1.870E-1
1.000E0
1 17
35 int:JPT1 JPT1 interactions 8.611E-3 3.395E-2
1.870E-1
1.000E0
1 17
36 int:SLAIN1 SLAIN1 interactions 9.620E-3 3.492E-2
1.923E-1
1.000E0
1 19
37 int:ITIH2 ITIH2 interactions 9.620E-3 3.492E-2
1.923E-1
1.000E0
1 19
38 int:TEDC1 TEDC1 interactions 1.012E-2 3.492E-2
1.923E-1
1.000E0
1 20
39 int:PNPLA2 PNPLA2 interactions 1.063E-2 3.492E-2
1.923E-1
1.000E0
1 21
40 int:OSBPL11 OSBPL11 interactions 1.063E-2 3.492E-2
1.923E-1
1.000E0
1 21
41 int:ITGA2B ITGA2B interactions 1.063E-2 3.492E-2
1.923E-1
1.000E0
1 21
42 int:KRT85 KRT85 interactions 1.063E-2 3.492E-2
1.923E-1
1.000E0
1 21
43 int:TBC1D2B TBC1D2B interactions 1.113E-2 3.572E-2
1.968E-1
1.000E0
1 22
44 int:TMTC3 TMTC3 interactions 1.214E-2 3.661E-2
2.017E-1
1.000E0
1 24
45 int:NUTM1 NUTM1 interactions 1.264E-2 3.661E-2
2.017E-1
1.000E0
1 25
46 int:ERMP1 ERMP1 interactions 1.314E-2 3.661E-2
2.017E-1
1.000E0
1 26
47 int:S100A11 S100A11 interactions 1.314E-2 3.661E-2
2.017E-1
1.000E0
1 26
48 int:NCF2 NCF2 interactions 1.365E-2 3.661E-2
2.017E-1
1.000E0
1 27
49 int:TRIB1 TRIB1 interactions 1.365E-2 3.661E-2
2.017E-1
1.000E0
1 27
50 int:ERCC6L ERCC6L interactions 1.365E-2 3.661E-2
2.017E-1
1.000E0
1 27
Show 45 more annotations

10: Cytoband [Display Chart] 9 input genes in category / 9 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Xq13.2-q21.1 Xq13.2-q21.1 2.597E-4 2.337E-3 6.611E-3 2.337E-3 1 1
2 10q11.2 10q11.2 4.406E-3 1.087E-2 3.076E-2 3.965E-2 1 17
3 1q23 1q23 5.957E-3 1.087E-2 3.076E-2
5.361E-2
1 23
4 5q35 5q35 6.215E-3 1.087E-2 3.076E-2
5.594E-2
1 24
5 1q25 1q25 6.990E-3 1.087E-2 3.076E-2
6.291E-2
1 27
6 13q14.2 13q14.2 7.248E-3 1.087E-2 3.076E-2
6.523E-2
1 28
7 16q24.1 16q24.1 9.310E-3 1.197E-2 3.386E-2
8.379E-2
1 36
8 19p13.12 19p13.12 1.317E-2 1.481E-2 4.190E-2
1.185E-1
1 51
9 17p13.1 17p13.1 3.124E-2 3.124E-2
8.838E-2
2.812E-1
1 122
Show 4 more annotations

11: Transcription Factor Binding Site [Display Chart] 9 input genes in category / 26 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 7 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 407 Arachidonate lipoxygenases genenames.org 1.902E-6 5.706E-6 1.398E-5 1.141E-5 2 6
2 204 Formyl peptide receptors|Leukotriene receptors genenames.org 1.902E-6 5.706E-6 1.398E-5 1.141E-5 2 6
3 832 Phospholipases|C2 domain containing phospholipases genenames.org 7.288E-3 1.458E-2 3.571E-2 4.373E-2 1 19
4 1003 Cytochrome P450 family 4 genenames.org 1.415E-2 1.926E-2 4.719E-2
8.491E-2
1 37
5 467 Phospholipases genenames.org 1.605E-2 1.926E-2 4.719E-2
9.630E-2
1 42

13: Coexpression [Display Chart] 9 input genes in category / 1051 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M2747 Genes down-regulated in MCF10A cells (breast cancer) upon knockdown of BRCA1 [Gene ID=672] gene by RNAi. MSigDB C6: Oncogenic Signatures (v6.0) 1.812E-5 7.792E-3
5.871E-2
1.904E-2 3 141
2 M17148 Genes down-regulated in granulocytes by RUNX1-RUNX1T1 [GeneID=861;862] fusion. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.824E-5 7.792E-3
5.871E-2
1.917E-2 2 17
3 M2526 Genes representing a co-expression network in atopic CD4 [GeneID=920] T lymphocyte responses. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.224E-5 7.792E-3
5.871E-2
2.337E-2 3 151
4 M7616 Genes up-regulated in CD8 T cells: naïve versus 3' memory. MSigDB C7: Immunologic Signatures (v6.0) 4.992E-5 9.336E-3
7.035E-2
5.247E-2
3 198
5 M5526 Genes up-regulated in comparison of neutrophils versus effector memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 5.144E-5 9.336E-3
7.035E-2
5.406E-2
3 200
6 M2213 Genes down-regulated in CD34+ [GeneID=947] cells by intermediate activity levels of STAT5A [GeneID=6776]; predominant long-term growth and self-renewal phenotype. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.203E-5 9.336E-3
7.035E-2
6.520E-2
3 213
7 19190338-Table1 Human StemCell Chau09 32genes GeneSigDB 6.218E-5 9.336E-3
7.035E-2
6.535E-2
2 31
8 19808960-Table2 Human Kidney Moore09 38genes GeneSigDB 7.497E-5 9.849E-3
7.422E-2
7.880E-2
2 34
9 M389 Top 50 most-increased mast cell specific genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.380E-4 1.611E-2
1.214E-1
1.450E-1
2 46
10 20460173-ImmPortChemokineReceptors Human Immune Kong10 53genes ImmPort ChemokineReceptors GeneSigDB 1.766E-4 1.856E-2
1.398E-1
1.856E-1
2 52
11 16818640-Table1 Human Brain Foltz06 95genes GeneSigDB 1.976E-4 1.888E-2
1.423E-1
2.077E-1
2 55
12 18768393-Table1 Human Viral Rodriguez-Caballero09 98genes GeneSigDB 4.395E-4 3.807E-2
2.869E-1
4.620E-1
2 82
13 20194811-SuppTable1 Human Lung not cancer Lockstone10 123genes GeneSigDB 7.330E-4 3.807E-2
2.869E-1
7.704E-1
2 106
14 M7876 Genes down-regulated in follicular epithelial stem cells after transgenic expression of GR [GeneID=2908] under control of the keratin5 (K5) [GeneID=3852] promoter. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.378E-4 3.807E-2
2.869E-1
9.856E-1
2 120
15 17483317-TableS4 Mouse Bone Boylan07 204genes GeneSigDB 1.133E-3 3.807E-2
2.869E-1
1.000E0
2 132
16 19190338-SuppTable1 Human StemCell Chau09 160genes GeneSigDB 1.219E-3 3.807E-2
2.869E-1
1.000E0
2 137
17 M10023 Genes down-regulated in NK cells versus B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.255E-3 3.807E-2
2.869E-1
1.000E0
2 139
18 M6918 Genes up-regulated in B lymphocytes: control versus CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 1.327E-3 3.807E-2
2.869E-1
1.000E0
2 143
19 15523429-Table1 Human HeadandNeck Zanation04 5genes GeneSigDB 1.555E-3 3.807E-2
2.869E-1
1.000E0
1 4
20 M6721 Genes up-regulated in 33D1+ spleen dendritic cells: Flt3L Melanom injected mice versus healthy controls. MSigDB C7: Immunologic Signatures (v6.0) 1.740E-3 3.807E-2
2.869E-1
1.000E0
2 164
21 M9087 Genes up-regulated in CD4 T conv: control versus over-expression of SATB1 [GeneID=6304]. MSigDB C7: Immunologic Signatures (v6.0) 1.803E-3 3.807E-2
2.869E-1
1.000E0
2 167
22 M9092 Genes up-regulated in CD4 T conv: control versus over-expression of XBP1 [GeneID=7494]. MSigDB C7: Immunologic Signatures (v6.0) 1.803E-3 3.807E-2
2.869E-1
1.000E0
2 167
23 M6816 Genes down-regulated in immature dendritic cells: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 1.846E-3 3.807E-2
2.869E-1
1.000E0
2 169
24 M6818 Genes down-regulated in dendritic cells: untreated versus anti-FcgRIIB. MSigDB C7: Immunologic Signatures (v6.0) 1.889E-3 3.807E-2
2.869E-1
1.000E0
2 171
25 M7635 Genes up-regulated in memory CD8 T cells: 3' versus 4'. MSigDB C7: Immunologic Signatures (v6.0) 2.090E-3 3.807E-2
2.869E-1
1.000E0
2 180
26 M2666 Genes down-regulated in mouse prostate by transgenic expression of human AKT1 gene [Gene ID=207] vs controls. MSigDB C6: Oncogenic Signatures (v6.0) 2.253E-3 3.807E-2
2.869E-1
1.000E0
2 187
27 15833844-Table2b Human Esophagus Kimchi05 06genes GeneSigDB 2.332E-3 3.807E-2
2.869E-1
1.000E0
1 6
28 M4224 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 24 h versus the untreated cells at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 2.398E-3 3.807E-2
2.869E-1
1.000E0
2 193
29 M6514 Genes up-regulated in epithelial cells (6h): untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 2.398E-3 3.807E-2
2.869E-1
1.000E0
2 193
30 M8624 Genes down-regulated in bone marrow-derived dendritic cells CSF2 [GeneID=1437] versus CSF2 [GeneID=1437] and high dose of 1,3-beta-D-oligoglucan [PubChem=11375554]. MSigDB C7: Immunologic Signatures (v6.0) 2.472E-3 3.807E-2
2.869E-1
1.000E0
2 196
31 M6075 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (2h) versus IL-12 (2h). MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 3.807E-2
2.869E-1
1.000E0
2 197
32 M5424 Genes up-regulated in comparison of eosinophils versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 2.521E-3 3.807E-2
2.869E-1
1.000E0
2 198
33 M3120 Genes up-regulated in comparison of peripheral mononuclear blood cells (PBMC) versus memory T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.521E-3 3.807E-2
2.869E-1
1.000E0
2 198
34 M3060 Genes up-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 high [GeneID=10219]. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 3.807E-2
2.869E-1
1.000E0
2 199
35 M5420 Genes up-regulated in comparison of eosinophils versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 3.807E-2
2.869E-1
1.000E0
2 199
36 M9484 Genes down-regulated in CD8 T cells, acute infection with LCMV-Armstrong: effectors at day 8 versus memory at day 30. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 3.807E-2
2.869E-1
1.000E0
2 199
37 M8169 Genes down-regulated in HEK293 cells: over-expressing wildtype NOD2 [GeneID=64127] versus control. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 3.807E-2
2.869E-1
1.000E0
2 199
38 M6453 Genes down-regulated in B lymphocytes: B2 versus B1. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
39 M6789 Genes down-regulated in lymph node B lymphocytes: untreated versus interferon beta. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
40 M5393 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 48 h versus neutrophils stimulated with LPS (TLR4 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
41 M3774 Genes up-regulated in comparison of control dendritic cells (DC) at 0 h versus those stimulated with Gardiquimod (TLR7 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
42 M9792 Genes up-regulated in B lymphocytes: naïve versus memory. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
43 M4434 Genes up-regulated in comparison of naive B cells versus memory IgM B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
44 M4057 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
45 M6398 Genes up-regulated in monocytes: untreated versus M. tuberculosis 19 kDa lipopeptide (3h). MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
46 M4636 Genes up-regulated in comparison of CD25- T cells treated with IL4 [GeneID=3565] at day 7 versus untreated CD25- T cells at day 7. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
47 M5450 Genes up-regulated in comparison of mast cells versus NK cells. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
48 M3082 Genes down-regulated in comparison of healthy B cells versus healthy myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
49 M8107 Genes up-regulated in IL10 [GeneID=3586] knockout macrophages: unstimulated versus stimulated by IL10 [GeneID=3586] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
50 M7289 Genes down-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 3.807E-2
2.869E-1
1.000E0
2 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 9 input genes in category / 1034 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSM854280 500 Myeloid Cells, DC.11cloSer.SI, CD45+ MHCII+ CD11c-lo CD11b+, Small Intestine, avg-5 Immgen.org, GSE15907 1.030E-5 3.761E-3 2.828E-2 1.065E-2 4 377
2 GSM854326 500 Myeloid Cells, MF.Microglia.CNS, CD45low CD11b+ F4/80+, Brain, avg-3 Immgen.org, GSE15907 1.393E-5 3.761E-3 2.828E-2 1.441E-2 4 407
3 GSM854294 500 Myeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 1.637E-5 3.761E-3 2.828E-2 1.692E-2 4 424
4 GSM605859 500 Myeloid Cells, MF.Thio5.II+480lo.PC, CD115+ MHC II+ F480lo SiglecF- CD11c+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 1.667E-5 3.761E-3 2.828E-2 1.724E-2 4 426
5 GSM605850 500 Myeloid Cells, MF.II-480hi.PC, F4/80hi CD115hi CD11b+ MHC II- CD11c-, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 1.860E-5 3.761E-3 2.828E-2 1.923E-2 4 438
6 Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Overall Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Overall Top 200 Genes Mouse Cell Atlas 4.691E-5 3.761E-3 2.828E-2 4.851E-2 3 183
7 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/basophil Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/basophil Tabula Muris Consortium 4.846E-5 3.761E-3 2.828E-2
5.010E-2
3 185
8 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND07-28 Top 200 Genes 5.329E-5 3.761E-3 2.828E-2
5.510E-2
3 191
9 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B Top 200 Genes 5.412E-5 3.761E-3 2.828E-2
5.596E-2
3 192
10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour Wilms U U/Kidney Tumour Wilms U14 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour Wilms U U/Kidney Tumour Wilms U14 Adult, Development, and Cancer types 5.496E-5 3.761E-3 2.828E-2
5.683E-2
3 193
11 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage - intermediate - unactivated Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage - intermediate - unactivated Top 200 Genes 6.020E-5 3.761E-3 2.828E-2
6.225E-2
3 199
12 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-D Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-D Top 200 Genes 6.294E-5 3.761E-3 2.828E-2
6.508E-2
3 202
13 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-D PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-D PND07-28 Top 200 Genes 6.294E-5 3.761E-3 2.828E-2
6.508E-2
3 202
14 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-A PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-A PND07-28 Top 200 Genes 6.481E-5 3.761E-3 2.828E-2
6.702E-2
3 204
15 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage - intermediate - unactivated E18.5 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage - intermediate - unactivated E18.5 Top 200 Genes 6.576E-5 3.761E-3 2.828E-2
6.800E-2
3 205
16 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype myeloid - neutrophil Lgals3-negative Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype myeloid - neutrophil Lgals3-negative Top 200 Genes 6.769E-5 3.761E-3 2.828E-2
6.999E-2
3 207
17 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype myeloid - neutrophil, Lgals3-negative PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype myeloid - neutrophil, Lgals3-negative PND07-28 Top 200 Genes 6.965E-5 3.761E-3 2.828E-2
7.202E-2
3 209
18 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype myeloid - neutrophil, Lgals3-negative PND01-03 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype myeloid - neutrophil, Lgals3-negative PND01-03 Top 200 Genes 7.576E-5 3.761E-3 2.828E-2
7.834E-2
3 215
19 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype Proliferative Myeloid Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype Proliferative Myeloid Top 200 Genes 7.894E-5 3.761E-3 2.828E-2
8.163E-2
3 218
20 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype Proliferative Myeloid E16.5 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype Proliferative Myeloid E16.5 Top 200 Genes 7.894E-5 3.761E-3 2.828E-2
8.163E-2
3 218
21 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-C PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-C PND07-28 Top 200 Genes 8.002E-5 3.761E-3 2.828E-2
8.274E-2
3 219
22 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-C Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-C Top 200 Genes 8.002E-5 3.761E-3 2.828E-2
8.274E-2
3 219
23 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND01-03 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND01-03 Top 200 Genes 1.103E-4 4.957E-3 3.727E-2
1.140E-1
3 244
24 gudmap RNAseq p2 Glomerlular Endothelial 2500 K2 gudmap RNAseq p2 Glomerlular Endothelial 2500 K2 Gudmap RNAseq 1.488E-4 6.409E-3 4.819E-2
1.538E-1
3 270
25 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype CD163+ Macrophage PND01-03 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype CD163+ Macrophage PND01-03 Top 200 Genes 1.727E-4 7.144E-3
5.371E-2
1.786E-1
3 284
26 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-B PND07-28 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-B PND07-28 Top 200 Genes 1.991E-4 7.775E-3
5.846E-2
2.058E-1
3 298
27 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-B Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-B Top 200 Genes 2.030E-4 7.775E-3
5.846E-2
2.099E-1
3 300
28 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype Mature Myeloid E16.5 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype Mature Myeloid E16.5 Top 200 Genes 2.258E-4 7.859E-3
5.909E-2
2.334E-1
3 311
29 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype Mature Myeloid Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype Mature Myeloid Top 200 Genes 2.258E-4 7.859E-3
5.909E-2
2.334E-1
3 311
30 BrainMap BrainAtlas - Mouse McCarroll Microglia.microglial.B.C1qb Microglia.microglial.B.C1qb Top 200 BrainMap BrainAtlas - Mouse McCarroll Microglia.microglial.B.C1qb Microglia.microglial.B.C1qb Top 200 BrainMap 2.388E-4 7.859E-3
5.909E-2
2.469E-1
3 317
31 BrainMap BrainAtlas - Mouse McCarroll Microglia.microglial.B.C1qb Microglia.microglial.B.C1qb Subtype Microglia.microglial.B.C1qb PosteriorCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Microglia.microglial.B.C1qb Microglia.microglial.B.C1qb Subtype Microglia.microglial.B.C1qb PosteriorCortex Top 200 Genes BrainMap 2.388E-4 7.859E-3
5.909E-2
2.469E-1
3 317
32 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage PND01-03 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage PND01-03 Top 200 Genes 2.547E-4 7.859E-3
5.909E-2
2.633E-1
3 324
33 Human Cell Atlas Human Cell Atlas Myeloid Myeloid Subtype CD34+ Eo/B/Mast Top 200 Genes Human Cell Atlas Human Cell Atlas Myeloid Myeloid Subtype CD34+ Eo/B/Mast Top 200 Genes 2.688E-4 7.859E-3
5.909E-2
2.779E-1
3 330
34 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage PND07-28 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage PND07-28 Top 200 Genes 2.688E-4 7.859E-3
5.909E-2
2.779E-1
3 330
35 Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Ileum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Ileum Top 200 Genes Mouse Cell Atlas 2.688E-4 7.859E-3
5.909E-2
2.779E-1
3 330
36 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage Top 200 Genes 2.736E-4 7.859E-3
5.909E-2
2.829E-1
3 332
37 Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Jejunum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Jejunum Top 200 Genes Mouse Cell Atlas 2.834E-4 7.921E-3
5.955E-2
2.931E-1
3 336
38 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Large Intestine/Brush cell of epithelium proper of large intestine Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Large Intestine/Brush cell of epithelium proper of large intestine Tabula Muris Consortium 3.006E-4 8.180E-3
6.150E-2
3.108E-1
2 64
39 Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Duodenum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Duodenum Top 200 Genes Mouse Cell Atlas 3.089E-4 8.191E-3
6.158E-2
3.194E-1
3 346
40 10X Human 8K PBMC B cells CD79A-MS4A1-CD79B Subtype B cells CD79A-MS4A1-CD79B-B cells subclass-0 (CD79A, IGHD, IGLC3) Top 200 Genes 10X Human 8K PBMC B cells CD79A-MS4A1-CD79B Subtype B cells CD79A-MS4A1-CD79B-B cells subclass-0 (CD79A, IGHD, IGLC3) Top 200 Genes 3.471E-4 8.972E-3
6.746E-2
3.589E-1
3 360
41 10X Human 8K PBMC B cells Subtype B cells-CD79A, IGHD, IGLC3 Top 200 Genes 10X Human 8K PBMC B cells Subtype B cells-CD79A, IGHD, IGLC3 Top 200 Genes 3.585E-4 9.034E-3
6.793E-2
3.707E-1
3 364
42 10X Human 8K PBMC B cell Subtype B cell-MS4A1, CD79A, CD79B Top 200 Genes 10X Human 8K PBMC B cell Subtype B cell-MS4A1, CD79A, CD79B Top 200 Genes 3.731E-4 9.034E-3
6.793E-2
3.858E-1
3 369
43 10X Human 8K PBMC B cells Subtype B cells-S100A8, LYZ, S100A9 Top 200 Genes 10X Human 8K PBMC B cells Subtype B cells-S100A8, LYZ, S100A9 Top 200 Genes 3.851E-4 9.034E-3
6.793E-2
3.982E-1
3 373
44 10X Human 68K PBMC Dendritic Subtype Dendritic-Dendritic c1 Top 200 Genes 10X Human 68K PBMC Dendritic Subtype Dendritic-Dendritic c1 Top 200 Genes 3.881E-4 9.034E-3
6.793E-2
4.013E-1
3 374
45 10X Human 68K PBMC Dendritic Subtype Dendritic-Dendritic c2 Top 200 Genes 10X Human 68K PBMC Dendritic Subtype Dendritic-Dendritic c2 Top 200 Genes 3.973E-4 9.034E-3
6.793E-2
4.109E-1
3 377
46 GSM777030 100 B cells, B.Pl.AA4-.BM, CD138+ AA4.1- CD43+, Bone marrow, avg-2 Immgen.org, GSE15907 4.019E-4 9.034E-3
6.793E-2
4.156E-1
2 74
47 10X Human 8K PBMC Myeloid Subtype Myeloid-LST1 CST3 AIF1 Top 200 Genes 10X Human 8K PBMC Myeloid Subtype Myeloid-LST1 CST3 AIF1 Top 200 Genes 4.258E-4 9.172E-3
6.896E-2
4.402E-1
3 386
48 10X Human 8K PBMC Myeloid Subtype Myeloid-S100A9 CST3 S100A8 Top 200 Genes 10X Human 8K PBMC Myeloid Subtype Myeloid-S100A9 CST3 S100A8 Top 200 Genes 4.258E-4 9.172E-3
6.896E-2
4.402E-1
3 386
49 GSM854294 100 Myeloid Cells, DC.II+480lo.PC, F4/80lo MHC II+ CD11c+ CD115+, Peritoneal Cavity, avg-3 Immgen.org, GSE15907 4.351E-4 9.181E-3
6.903E-2
4.499E-1
2 77
50 GSM777030 500 B cells, B.Pl.AA4-.BM, CD138+ AA4.1- CD43+, Bone marrow, avg-2 Immgen.org, GSE15907 4.521E-4 9.181E-3
6.903E-2
4.675E-1
3 394
Show 45 more annotations

15: Computational [Display Chart] 6 input genes in category / 52 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 9 input genes in category / 123 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-let-7i*:mirSVR lowEffct hsa-let-7i*:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 5.675E-4 3.610E-2
1.947E-1
6.980E-2
2 290
2 hsa-miR-4755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.871E-4 3.610E-2
1.947E-1
7.221E-2
2 295

17: Drug [Display Chart] 9 input genes in category / 2502 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000000169 6-trans-leukotriene B4 Stitch 1.489E-15 3.725E-12 3.130E-11 3.725E-12 8 247
2 CID000003934 15-epi-lipoxin A4 Stitch 5.244E-15 6.560E-12 5.512E-11 1.312E-11 7 128
3 CID000001831 AC1L1CC6 Stitch 3.497E-14 2.916E-11 2.450E-10 8.749E-11 6 65
4 CID000003907 LTC4 (leukotriene C4 Stitch 5.964E-14 3.730E-11 3.134E-10 1.492E-10 7 180
5 CID000105049 L-663,536 Stitch 1.372E-13 6.863E-11 5.767E-10 3.432E-10 6 81
6 CID000119331 L-649,923 Stitch 2.383E-13 9.938E-11 8.350E-10 5.963E-10 5 28
7 CID000000859 leukotriene-C4 Stitch 4.118E-13 1.472E-10 1.237E-9 1.030E-9 5 31
8 CID000115219 ICI 198,615 Stitch 6.742E-13 2.108E-10 1.772E-9 1.687E-9 5 34
9 CID000005059 REV 5901 Stitch 1.394E-12 3.875E-10 3.256E-9 3.488E-9 5 39
10 CID003522488 AC1MRR4N Stitch 2.329E-12 5.828E-10 4.896E-9 5.828E-9 5 43
11 CID000001772 AC1L1C7C Stitch 5.121E-12 1.165E-9 9.788E-9 1.281E-8 5 50
12 CID000003969 LY171883 Stitch 5.677E-12 1.184E-9 9.946E-9 1.420E-8 5 51
13 CID000003908 AC1L1GZB Stitch 1.151E-11 2.199E-9 1.847E-8 2.881E-8 6 167
14 CID006437373 piriprost Stitch 1.318E-11 2.199E-9 1.847E-8 3.298E-8 5 60
15 CID000060490 zileuton Stitch 1.318E-11 2.199E-9 1.847E-8 3.298E-8 5 60
16 CID000001967 AA-861 Stitch 1.436E-11 2.245E-9 1.886E-8 3.592E-8 5 61
17 CID005071481 BAY u9773 Stitch 2.639E-11 3.884E-9 3.263E-8 6.603E-8 4 17
18 CID000122212 FPL 57231 Stitch 3.392E-11 4.715E-9 3.962E-8 8.487E-8 4 18
19 CID000122182 L-651,392 Stitch 5.369E-11 7.070E-9 5.941E-8 1.343E-7 4 20
20 CID000003909 11-trans-leukotriene E4 Stitch 5.785E-11 7.238E-9 6.081E-8 1.448E-7 5 80
21 CID006449854 U-75302 Stitch 6.631E-11 7.901E-9 6.639E-8 1.659E-7 4 21
22 CID000060842 SKF 104353 Stitch 1.177E-10 1.338E-8 1.124E-7 2.944E-7 4 24
23 CID000001771 5-HETE Stitch 1.318E-10 1.434E-8 1.205E-7 3.298E-7 5 94
24 CID000001035 AC1L1AL2 Stitch 3.675E-10 3.831E-8 3.219E-7 9.194E-7 5 115
25 CID000005461 TXB2 (thromboxane B2 Stitch 4.187E-10 4.191E-8 3.521E-7 1.048E-6 5 118
26 ctd:D017997 Leukotriene C4 CTD 5.787E-10 5.363E-8 4.506E-7 1.448E-6 4 35
27 ctd:C093875 montelukast CTD 5.787E-10 5.363E-8 4.506E-7 1.448E-6 4 35
28 CID000129110 Wy-45,911 Stitch 8.455E-10 7.555E-8 6.348E-7 2.115E-6 3 6
29 CID000461545 AGEPC Stitch 1.110E-9 9.325E-8 7.835E-7 2.777E-6 6 356
30 CID000003935 AC1L1H1K Stitch 1.118E-9 9.325E-8 7.835E-7 2.798E-6 4 41
31 CID000001415 12-HPETE Stitch 1.362E-9 1.099E-7 9.237E-7 3.408E-6 4 43
32 ctd:D017999 Leukotriene E4 CTD 2.366E-9 1.692E-7 1.421E-6 5.921E-6 3 8
33 ctd:C047681 pranlukast CTD 2.366E-9 1.692E-7 1.421E-6 5.921E-6 3 8
34 CID005283126 LTB4-dimethylamide Stitch 2.366E-9 1.692E-7 1.421E-6 5.921E-6 3 8
35 CID000129968 RG 7152 Stitch 2.366E-9 1.692E-7 1.421E-6 5.921E-6 3 8
36 CID000105007 FPL 55712 Stitch 3.484E-9 2.277E-7 1.913E-6 8.717E-6 4 54
37 CID006439604 14,15-leukotriene A4 Stitch 3.549E-9 2.277E-7 1.913E-6 8.880E-6 3 9
38 CID000164859 L583,916 Stitch 3.549E-9 2.277E-7 1.913E-6 8.880E-6 3 9
39 CID000122010 L-648051 Stitch 3.549E-9 2.277E-7 1.913E-6 8.880E-6 3 9
40 CID003643892 AC1MUNZL Stitch 4.045E-9 2.530E-7 2.126E-6 1.012E-5 4 56
41 CID000126145 SKF 102922 Stitch 5.069E-9 3.093E-7 2.599E-6 1.268E-5 3 10
42 CID000002881 sodium cromoglycate Stitch 6.552E-9 3.903E-7 3.279E-6 1.639E-5 4 63
43 CID000126778 LY163443 Stitch 6.969E-9 4.055E-7 3.407E-6 1.744E-5 3 11
44 CID000004534 NDGA Stitch 8.822E-9 5.017E-7 4.215E-6 2.207E-5 5 216
45 CID000001993 methacholine Stitch 9.029E-9 5.020E-7 4.218E-6 2.259E-5 5 217
46 CID006445784 AC1O637I Stitch 9.290E-9 5.053E-7 4.245E-6 2.324E-5 3 12
47 CID000449205 1xp1 Stitch 1.007E-8 5.362E-7 4.505E-6 2.520E-5 4 70
48 CID000114873 thromboxane Stitch 1.035E-8 5.396E-7 4.534E-6 2.590E-5 5 223
49 CID000060719 AC1L1TSE Stitch 1.130E-8 5.769E-7 4.847E-6 2.827E-5 4 72
50 CID000443116 S-decyl-GSH Stitch 1.207E-8 6.042E-7 5.077E-6 3.021E-5 3 13
Show 45 more annotations

18: Disease [Display Chart] 9 input genes in category / 200 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0004099 Asthma, Exercise-Induced DisGeNET BeFree 1.185E-10 1.694E-8 9.958E-8 2.369E-8 3 3
2 C1319853 Asthma, Aspirin-Induced DisGeNET Curated 1.694E-10 1.694E-8 9.958E-8 3.388E-8 4 19
3 C0042109 Urticaria DisGeNET Curated 6.185E-10 4.124E-8 2.424E-7 1.237E-7 5 91
4 C0013182 Drug Allergy DisGeNET Curated 3.974E-9 1.657E-7 9.737E-7 7.947E-7 4 40
5 C0543699 ASA intolerant asthma DisGeNET BeFree 4.141E-9 1.657E-7 9.737E-7 8.283E-7 3 7
6 C0035242 Respiratory Tract Diseases DisGeNET Curated 1.710E-8 5.701E-7 3.351E-6 3.421E-6 4 57
7 C0035204 Respiration Disorders DisGeNET Curated 5.239E-8 1.497E-6 8.799E-6 1.048E-5 4 75
8 C0155877 Allergic asthma DisGeNET BeFree 2.545E-6 6.363E-5 3.740E-4 5.090E-4 4 197
9 C0162871 Aortic Aneurysm, Abdominal DisGeNET Curated 8.015E-6 1.781E-4 1.047E-3 1.603E-3 4 263
10 C0085129 Bronchial Hyperreactivity DisGeNET Curated 1.026E-5 2.053E-4 1.206E-3 2.053E-3 3 82
11 C0004059 aspirin intolerance DisGeNET BeFree 1.804E-5 3.281E-4 1.929E-3 3.609E-3 2 12
12 C3272363 Ischemic Cerebrovascular Accident DisGeNET BeFree 2.207E-5 3.679E-4 2.163E-3 4.415E-3 4 340
13 C0948008 Ischemic stroke DisGeNET Curated 3.012E-5 4.634E-4 2.724E-3 6.025E-3 4 368
14 C0948780 Rhinosinusitis DisGeNET BeFree 3.713E-5 5.304E-4 3.118E-3 7.426E-3 2 17
15 C0011609 Drug Eruptions DisGeNET Curated 6.895E-5 9.194E-4 5.404E-3 1.379E-2 2 23
16 C0037315 Sleep Apnea Syndromes DisGeNET Curated 2.115E-4 2.644E-3 1.554E-2 4.231E-2 2 40
17 C3539909 Allergic disposition DisGeNET BeFree 3.051E-4 3.589E-3 2.110E-2
6.101E-2
3 256
18 C3279662 Leukotriene C4 Synthase Deficiency DisGeNET Curated 5.554E-4 5.837E-3 3.431E-2
1.111E-1
1 1
19 cv:C1855503 Leukotriene c4 synthase deficiency Clinical Variations 5.554E-4 5.837E-3 3.431E-2
1.111E-1
1 1
20 C0035455 Rhinitis DisGeNET Curated 5.950E-4 5.837E-3 3.431E-2
1.190E-1
2 67
21 C0018621 Hay fever DisGeNET Curated 6.129E-4 5.837E-3 3.431E-2
1.226E-1
2 68
22 C0149516 Chronic sinusitis DisGeNET Curated 7.851E-4 7.138E-3 4.196E-2
1.570E-1
2 77
23 20081125:Weidinger Serum IgE levels GWAS 1.110E-3 9.656E-3
5.676E-2
2.221E-1
1 2
24 C0004135 Ataxia Telangiectasia DisGeNET Curated 1.180E-3 9.835E-3
5.781E-2
2.360E-1
3 407
25 C0023485 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma DisGeNET Curated 1.319E-3 1.056E-2
6.205E-2
2.639E-1
2 100
26 C0036690 Septicemia DisGeNET Curated 1.577E-3 1.110E-2
6.526E-2
3.154E-1
3 450
27 C0020429 Hyperalgesia DisGeNET Curated 1.622E-3 1.110E-2
6.526E-2
3.244E-1
2 111
28 20090330:Takeuchi Warfarin maintenance dose GWAS 1.665E-3 1.110E-2
6.526E-2
3.331E-1
1 3
29 20081125:Valdes Knee osteoarthritis GWAS 1.665E-3 1.110E-2
6.526E-2
3.331E-1
1 3
30 C1960047 Moderate persistent asthma DisGeNET BeFree 1.665E-3 1.110E-2
6.526E-2
3.331E-1
1 3
31 C0243026 Sepsis DisGeNET Curated 2.110E-3 1.361E-2
8.002E-2
4.220E-1
3 498
32 20090724:Teichert Acenocoumarol maintenance dosage GWAS 2.220E-3 1.387E-2
8.155E-2
4.440E-1
1 4
33 C0741250 aspirin sensitivity DisGeNET BeFree 2.774E-3 1.681E-2
9.883E-2
5.548E-1
1 5
34 C0026766 Multiple Organ Failure DisGeNET Curated 3.882E-3 1.991E-2
1.171E-1
7.764E-1
1 7
35 C0151971 Primary ulcer of intestine DisGeNET BeFree 3.882E-3 1.991E-2
1.171E-1
7.764E-1
1 7
36 C2825139 Acute Myeloid Leukemia with Myelodysplasia-Related Changes DisGeNET BeFree 3.882E-3 1.991E-2
1.171E-1
7.764E-1
1 7
37 C1260881 Allergic bronchitis DisGeNET BeFree 3.882E-3 1.991E-2
1.171E-1
7.764E-1
1 7
38 C1112157 Intrauterine infection DisGeNET BeFree 3.882E-3 1.991E-2
1.171E-1
7.764E-1
1 7
39 C0011603 Dermatitis DisGeNET Curated 3.883E-3 1.991E-2
1.171E-1
7.767E-1
2 173
40 C1512981 Mammary Tumorigenesis DisGeNET BeFree 4.061E-3 2.030E-2
1.193E-1
8.121E-1
2 177
41 C0346373 Malignant melanoma of iris DisGeNET Curated 4.435E-3 2.112E-2
1.241E-1
8.871E-1
1 8
42 C0376618 Endotoxemia DisGeNET Curated 4.435E-3 2.112E-2
1.241E-1
8.871E-1
1 8
43 C0274306 Cutaneous anaphylaxis DisGeNET BeFree 4.989E-3 2.320E-2
1.364E-1
9.977E-1
1 9
44 C0027430 Nasal Polyps DisGeNET Curated 5.356E-3 2.435E-2
1.431E-1
1.000E0
2 204
45 20081125:Benjamin Select biomarker traits GWAS 6.094E-3 2.709E-2
1.592E-1
1.000E0
1 11
46 C0233794 Memory impairment DisGeNET Curated 6.535E-3 2.828E-2
1.662E-1
1.000E0
2 226
47 cv:C1869116 Asthma, susceptibility to Clinical Variations 6.647E-3 2.828E-2
1.662E-1
1.000E0
1 12
48 OMIN:600807 ASTHMA, SUSCEPTIBILITY TO OMIM 7.199E-3 2.938E-2
1.727E-1
1.000E0
1 13
49 C0040560 Toxoplasmosis, Congenital DisGeNET BeFree 7.199E-3 2.938E-2
1.727E-1
1.000E0
1 13
50 C0270724 Infantile Neuroaxonal Dystrophy DisGeNET Curated 7.750E-3 3.044E-2
1.789E-1
1.000E0
1 14
Show 45 more annotations