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1: GO: Molecular Function [Display Chart] 486 annotations before applied cutoff / 18819 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding 1.103E-13 5.361E-11 3.626E-10 5.361E-11 22 678
2 GO:0044212 transcription regulatory region DNA binding 1.598E-12 2.239E-10 1.514E-9 7.765E-10 23 862
3 GO:0000975 regulatory region DNA binding 1.716E-12 2.239E-10 1.514E-9 8.340E-10 23 865
4 GO:0001067 regulatory region nucleic acid binding 1.843E-12 2.239E-10 1.514E-9 8.955E-10 23 868
5 GO:0003690 double-stranded DNA binding 5.358E-12 5.208E-10 3.523E-9 2.604E-9 22 824
6 GO:0000976 transcription regulatory region sequence-specific DNA binding 2.021E-11 1.637E-9 1.107E-8 9.823E-9 20 705
7 GO:1990837 sequence-specific double-stranded DNA binding 4.366E-11 3.031E-9 2.050E-8 2.122E-8 20 736
8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding 1.004E-10 6.102E-9 4.128E-8 4.882E-8 15 380
9 GO:0000987 core promoter proximal region sequence-specific DNA binding 1.983E-10 1.001E-8 6.770E-8 9.636E-8 15 399
10 GO:0001159 core promoter proximal region DNA binding 2.125E-10 1.001E-8 6.770E-8 1.033E-7 15 401
11 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding 2.265E-10 1.001E-8 6.770E-8 1.101E-7 18 632
12 GO:0001012 RNA polymerase II regulatory region DNA binding 2.638E-10 1.068E-8 7.226E-8 1.282E-7 18 638
13 GO:0003712 transcription cofactor activity 3.438E-10 1.285E-8 8.693E-8 1.671E-7 17 566
14 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding 5.096E-10 1.769E-8 1.197E-7 2.477E-7 14 358
15 GO:0000989 transcription factor activity, transcription factor binding 1.131E-9 3.663E-8 2.478E-7 5.495E-7 17 612
16 GO:0000988 transcription factor activity, protein binding 1.248E-9 3.790E-8 2.564E-7 6.064E-7 17 616
17 GO:0008134 transcription factor binding 4.659E-9 1.332E-7 9.009E-7 2.264E-6 16 585
18 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding 6.906E-9 1.865E-7 1.261E-6 3.356E-6 13 365
19 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding 4.587E-7 1.173E-5 7.937E-5 2.229E-4 7 107
20 GO:0003713 transcription coactivator activity 1.101E-6 2.677E-5 1.811E-4 5.353E-4 10 311
21 GO:0003682 chromatin binding 2.625E-6 6.074E-5 4.109E-4 1.276E-3 12 516
22 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding 1.011E-5 2.233E-4 1.510E-3 4.912E-3 4 31
23 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding 1.118E-5 2.362E-4 1.598E-3 5.433E-3 6 114
24 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding 1.576E-5 3.191E-4 2.158E-3 7.658E-3 7 182
25 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding 1.870E-5 3.635E-4 2.459E-3 9.087E-3 8 259
26 GO:0046982 protein heterodimerization activity 4.334E-5 8.102E-4 5.480E-3 2.106E-2 11 575
27 GO:0003714 transcription corepressor activity 8.246E-5 1.484E-3 1.004E-2 4.008E-2 7 236
28 GO:0035326 enhancer binding 1.056E-4 1.833E-3 1.240E-2
5.133E-2
 5 106
29 GO:0003725 double-stranded RNA binding 2.311E-4 3.873E-3 2.620E-2
1.123E-1
 4 68
30 GO:0043425 bHLH transcription factor binding 3.082E-4 4.993E-3 3.377E-2
1.498E-1
 3 30
31 GO:0019900 kinase binding 9.258E-4 1.451E-2
9.818E-2
4.499E-1
 10 693
32 GO:0042803 protein homodimerization activity 1.011E-3 1.536E-2
1.039E-1
4.914E-1
 11 829
33 GO:0031072 heat shock protein binding 1.242E-3 1.829E-2
1.237E-1
6.036E-1
 4 106
34 GO:0019904 protein domain specific binding 1.398E-3 1.998E-2
1.352E-1
6.793E-1
 10 732
35 GO:0019901 protein kinase binding 1.655E-3 2.203E-2
1.490E-1
8.045E-1
 9 622
36 GO:0042826 histone deacetylase binding 1.677E-3 2.203E-2
1.490E-1
8.152E-1
 4 115
37 GO:0001046 core promoter sequence-specific DNA binding 1.677E-3 2.203E-2
1.490E-1
8.152E-1
 4 115
38 GO:0008092 cytoskeletal protein binding 1.753E-3 2.242E-2
1.517E-1
8.519E-1
 11 888
39 GO:0004672 protein kinase activity 2.210E-3 2.754E-2
1.863E-1
1.000E0
 9 649
40 GO:0033613 activating transcription factor binding 2.476E-3 3.009E-2
2.035E-1
1.000E0
 3 61
41 GO:0051015 actin filament binding 2.925E-3 3.434E-2
2.323E-1
1.000E0
 4 134
42 GO:0003684 damaged DNA binding 2.968E-3 3.434E-2
2.323E-1
1.000E0
 3 65
43 GO:0035173 histone kinase activity 3.130E-3 3.538E-2
2.393E-1
1.000E0
 2 19
44 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding 3.810E-3 4.208E-2
2.847E-1
1.000E0
 3 71
45 GO:0043997 histone acetyltransferase activity (H4-K12 specific) 4.430E-3 4.485E-2
3.034E-1
1.000E0
 1 1
46 GO:0070335 aspartate binding 4.430E-3 4.485E-2
3.034E-1
1.000E0
 1 1
47 GO:0043035 chromatin insulator sequence binding 4.430E-3 4.485E-2
3.034E-1
1.000E0
 1 1
48 GO:1901707 leptomycin B binding 4.430E-3 4.485E-2
3.034E-1
1.000E0
 1 1
49 GO:0071837 HMG box domain binding 4.578E-3 4.541E-2
3.072E-1
1.000E0
 2 23
50 GO:0046332 SMAD binding 4.785E-3 4.651E-2
3.146E-1
1.000E0
 3 77
Show 45 more annotations

2: GO: Biological Process [Display Chart] 2907 annotations before applied cutoff / 18785 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0061061 muscle structure development 5.030E-10 1.462E-6 1.251E-5 1.462E-6 18 663
2 GO:0000122 negative regulation of transcription from RNA polymerase II promoter 1.755E-9 2.551E-6 2.182E-5 5.103E-6 19 810
3 GO:0002520 immune system development 1.452E-7 1.212E-4 1.037E-3 4.221E-4 18 956
4 GO:0030097 hemopoiesis 1.668E-7 1.212E-4 1.037E-3 4.849E-4 17 858
5 GO:0007517 muscle organ development 2.382E-7 1.292E-4 1.105E-3 6.925E-4 12 410
6 GO:0042692 muscle cell differentiation 2.712E-7 1.292E-4 1.105E-3 7.884E-4 12 415
7 GO:0048534 hematopoietic or lymphoid organ development 3.543E-7 1.292E-4 1.105E-3 1.030E-3 17 905
8 GO:0043009 chordate embryonic development 3.556E-7 1.292E-4 1.105E-3 1.034E-3 15 698
9 GO:0009792 embryo development ending in birth or egg hatching 4.185E-7 1.352E-4 1.156E-3 1.216E-3 15 707
10 GO:0001101 response to acid chemical 7.146E-7 2.077E-4 1.777E-3 2.077E-3 11 372
11 GO:1901698 response to nitrogen compound 1.102E-6 2.912E-4 2.490E-3 3.203E-3 17 982
12 GO:0071396 cellular response to lipid 1.292E-6 3.131E-4 2.678E-3 3.757E-3 13 573
13 GO:0014706 striated muscle tissue development 1.488E-6 3.328E-4 2.846E-3 4.326E-3 11 401
14 GO:0055012 ventricular cardiac muscle cell differentiation 1.626E-6 3.377E-4 2.888E-3 4.728E-3 4 20
15 GO:0060537 muscle tissue development 2.277E-6 4.412E-4 3.773E-3 6.618E-3 11 419
16 GO:0071229 cellular response to acid chemical 3.560E-6 6.468E-4 5.531E-3 1.035E-2 8 206
17 GO:0031056 regulation of histone modification 4.114E-6 7.035E-4 6.017E-3 1.196E-2 7 148
18 GO:0035065 regulation of histone acetylation 5.212E-6 8.028E-4 6.866E-3 1.515E-2 5 57
19 GO:0010243 response to organonitrogen compound 5.247E-6 8.028E-4 6.866E-3 1.525E-2 15 867
20 GO:0043543 protein acylation 7.757E-6 1.128E-3 9.643E-3 2.255E-2 8 229
21 GO:2000756 regulation of peptidyl-lysine acetylation 8.570E-6 1.163E-3 9.946E-3 2.491E-2 5 63
22 GO:0048568 embryonic organ development 8.815E-6 1.163E-3 9.946E-3 2.563E-2 11 483
23 GO:0043618 regulation of transcription from RNA polymerase II promoter in response to stress 9.264E-6 1.163E-3 9.946E-3 2.693E-2 5 64
24 GO:0051101 regulation of DNA binding 9.689E-6 1.163E-3 9.946E-3 2.817E-2 6 111
25 GO:0043967 histone H4 acetylation 1.000E-5 1.163E-3 9.946E-3 2.907E-2 5 65
26 GO:1902275 regulation of chromatin organization 1.063E-5 1.189E-3 1.017E-2 3.090E-2 7 171
27 GO:0043966 histone H3 acetylation 1.161E-5 1.250E-3 1.069E-2 3.376E-2 5 67
28 GO:0051147 regulation of muscle cell differentiation 1.236E-5 1.283E-3 1.097E-2 3.593E-2 7 175
29 GO:1901983 regulation of protein acetylation 1.342E-5 1.345E-3 1.151E-2 3.901E-2 5 69
30 GO:0043620 regulation of DNA-templated transcription in response to stress 1.440E-5 1.396E-3 1.194E-2 4.187E-2 5 70
31 GO:0051098 regulation of binding 1.730E-5 1.622E-3 1.387E-2
5.029E-2
 9 336
32 GO:0007080 mitotic metaphase plate congression 2.094E-5 1.902E-3 1.627E-2
6.087E-2
 4 37
33 GO:0007519 skeletal muscle tissue development 2.251E-5 1.962E-3 1.678E-2
6.544E-2
 7 192
34 GO:0035914 skeletal muscle cell differentiation 2.295E-5 1.962E-3 1.678E-2
6.672E-2
 5 77
35 GO:0006473 protein acetylation 2.655E-5 2.205E-3 1.886E-2
7.719E-2
 7 197
36 GO:0006259 DNA metabolic process 2.779E-5 2.244E-3 1.919E-2
8.079E-2
 15 998
37 GO:0030098 lymphocyte differentiation 2.912E-5 2.288E-3 1.957E-2
8.466E-2
 9 359
38 GO:0016570 histone modification 3.039E-5 2.324E-3 1.987E-2
8.835E-2
 10 453
39 GO:0060538 skeletal muscle organ development 3.117E-5 2.324E-3 1.987E-2
9.062E-2
 7 202
40 GO:0071407 cellular response to organic cyclic compound 3.580E-5 2.580E-3 2.206E-2
1.041E-1
 11 562
41 GO:0010035 response to inorganic substance 3.638E-5 2.580E-3 2.206E-2
1.058E-1
 11 563
42 GO:0007584 response to nutrient 3.874E-5 2.645E-3 2.262E-2
1.126E-1
 7 209
43 GO:1903706 regulation of hemopoiesis 3.924E-5 2.645E-3 2.262E-2
1.141E-1
 9 373
44 GO:0016569 covalent chromatin modification 4.003E-5 2.645E-3 2.262E-2
1.164E-1
 10 468
45 GO:0045445 myoblast differentiation 4.147E-5 2.679E-3 2.291E-2
1.205E-1
 5 87
46 GO:0051129 negative regulation of cellular component organization 4.476E-5 2.682E-3 2.294E-2
1.301E-1
 12 684
47 GO:0042542 response to hydrogen peroxide 4.588E-5 2.682E-3 2.294E-2
1.334E-1
 6 146
48 GO:0035051 cardiocyte differentiation 4.588E-5 2.682E-3 2.294E-2
1.334E-1
 6 146
49 GO:0051310 metaphase plate congression 4.599E-5 2.682E-3 2.294E-2
1.337E-1
 4 45
50 GO:0006974 cellular response to DNA damage stimulus 4.613E-5 2.682E-3 2.294E-2
1.341E-1
 13 800
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 287 annotations before applied cutoff / 19172 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0044427 chromosomal part 5.576E-12 9.868E-10 6.156E-9 1.600E-9 22 841
2 GO:0005694 chromosome 6.877E-12 9.868E-10 6.156E-9 1.974E-9 23 943
3 GO:0000228 nuclear chromosome 1.966E-8 1.555E-6 9.698E-6 5.643E-6 15 570
4 GO:0000785 chromatin 2.167E-8 1.555E-6 9.698E-6 6.219E-6 14 489
5 GO:0005667 transcription factor complex 6.132E-8 3.026E-6 1.887E-5 1.760E-5 12 369
6 GO:0044454 nuclear chromosome part 6.325E-8 3.026E-6 1.887E-5 1.815E-5 14 533
7 GO:0005819 spindle 8.890E-8 3.645E-6 2.274E-5 2.552E-5 11 308
8 GO:0005925 focal adhesion 7.504E-6 2.672E-4 1.667E-3 2.154E-3 10 393
9 GO:0005924 cell-substrate adherens junction 8.380E-6 2.672E-4 1.667E-3 2.405E-3 10 398
10 GO:0030055 cell-substrate junction 9.343E-6 2.682E-4 1.673E-3 2.682E-3 10 403
11 GO:0098687 chromosomal region 1.817E-5 4.448E-4 2.775E-3 5.216E-3 9 345
12 GO:1990622 CHOP-ATF3 complex 1.860E-5 4.448E-4 2.775E-3 5.337E-3 2 2
13 GO:0005912 adherens junction 4.480E-5 9.891E-4 6.171E-3 1.286E-2 10 484
14 GO:0070161 anchoring junction 6.184E-5 1.268E-3 7.909E-3 1.775E-2 10 503
15 GO:0000790 nuclear chromatin 8.359E-5 1.599E-3 9.978E-3 2.399E-2 8 326
16 GO:0090575 RNA polymerase II transcription factor complex 9.261E-5 1.661E-3 1.036E-2 2.658E-2 5 105
17 GO:0000775 chromosome, centromeric region 1.518E-4 2.562E-3 1.599E-2 4.356E-2 6 185
18 GO:0030125 clathrin vesicle coat 1.680E-4 2.678E-3 1.671E-2 4.821E-2 3 25
19 GO:0000793 condensed chromosome 2.859E-4 3.968E-3 2.475E-2
8.207E-2
 6 208
20 GO:0044798 nuclear transcription factor complex 2.903E-4 3.968E-3 2.475E-2
8.333E-2
 5 134
21 GO:0000784 nuclear chromosome, telomeric region 2.903E-4 3.968E-3 2.475E-2
8.333E-2
 5 134
22 GO:0030665 clathrin-coated vesicle membrane 4.627E-4 6.036E-3 3.766E-2
1.328E-1
 4 83
23 GO:0042788 polysomal ribosome 6.536E-4 8.156E-3
5.088E-2
1.876E-1
 2 9
24 GO:0000781 chromosome, telomeric region 7.109E-4 8.501E-3
5.303E-2
2.040E-1
 5 163
25 GO:0042555 MCM complex 9.930E-4 1.140E-2
7.111E-2
2.850E-1
 2 11
26 GO:0030120 vesicle coat 1.176E-3 1.263E-2
7.879E-2
3.375E-1
 3 48
27 GO:0030130 clathrin coat of trans-Golgi network vesicle 1.188E-3 1.263E-2
7.879E-2
3.410E-1
 2 12
28 GO:0005652 nuclear lamina 1.400E-3 1.388E-2
8.660E-2
4.019E-1
 2 13
29 GO:0030118 clathrin coat 1.403E-3 1.388E-2
8.660E-2
4.026E-1
 3 51
30 GO:0005844 polysome 1.484E-3 1.420E-2
8.856E-2
4.259E-1
 3 52
31 GO:0005730 nucleolus 1.597E-3 1.478E-2
9.223E-2
4.583E-1
 11 894
32 GO:0005637 nuclear inner membrane 1.838E-3 1.630E-2
1.017E-1
5.276E-1
 3 56
33 GO:0012510 trans-Golgi network transport vesicle membrane 1.874E-3 1.630E-2
1.017E-1
5.380E-1
 2 15
34 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex 2.136E-3 1.752E-2
1.093E-1
6.131E-1
 2 16
35 GO:0097038 perinuclear endoplasmic reticulum 2.136E-3 1.752E-2
1.093E-1
6.131E-1
 2 16
36 GO:0010369 chromocenter 2.414E-3 1.925E-2
1.201E-1
6.929E-1
 2 17
37 GO:0072686 mitotic spindle 2.695E-3 2.091E-2
1.304E-1
7.735E-1
 3 64
38 GO:0030132 clathrin coat of coated pit 3.019E-3 2.280E-2
1.422E-1
8.663E-1
 2 19
39 GO:0005905 clathrin-coated pit 3.337E-3 2.419E-2
1.509E-1
9.577E-1
 3 69
40 GO:0030662 coated vesicle membrane 3.371E-3 2.419E-2
1.509E-1
9.676E-1
 4 142
41 GO:0030135 coated vesicle 3.945E-3 2.760E-2
1.722E-1
1.000E0
 5 241
42 GO:1990234 transferase complex 4.039E-3 2.760E-2
1.722E-1
1.000E0
 9 724
43 GO:0070421 DNA ligase III-XRCC1 complex 4.348E-3 2.836E-2
1.769E-1
1.000E0
 1 1
44 GO:0035976 transcription factor AP-1 complex 4.348E-3 2.836E-2
1.769E-1
1.000E0
 1 1
45 GO:0030136 clathrin-coated vesicle 5.380E-3 3.431E-2
2.140E-1
1.000E0
 4 162
46 GO:0000123 histone acetyltransferase complex 6.799E-3 4.242E-2
2.646E-1
1.000E0
 3 89
47 GO:0030140 trans-Golgi network transport vesicle 7.446E-3 4.547E-2
2.836E-1
1.000E0
 2 30
48 GO:0030117 membrane coat 8.135E-3 4.592E-2
2.865E-1
1.000E0
 3 95
49 GO:0048475 coated membrane 8.135E-3 4.592E-2
2.865E-1
1.000E0
 3 95
50 GO:0005901 caveola 8.372E-3 4.592E-2
2.865E-1
1.000E0
 3 96
Show 45 more annotations

4: Human Phenotype [Display Chart] 311 annotations before applied cutoff / 1813 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 2309 annotations before applied cutoff / 9208 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0005460 abnormal leukopoiesis 6.583E-11 8.660E-8 7.207E-7 1.520E-7 25 733
2 MP:0002123 abnormal definitive hematopoiesis 7.501E-11 8.660E-8 7.207E-7 1.732E-7 28 940
3 MP:0013693 abnormal hemopoiesis 1.430E-10 1.101E-7 9.161E-7 3.302E-7 28 966
4 MP:0002401 abnormal lymphopoiesis 5.915E-9 3.414E-6 2.841E-5 1.366E-5 21 634
5 MP:0005017 decreased B cell number 5.227E-8 2.396E-5 1.994E-4 1.207E-4 17 463
6 MP:0002458 abnormal B cell number 8.635E-8 2.396E-5 1.994E-4 1.994E-4 19 604
7 MP:0004939 abnormal B cell morphology 9.246E-8 2.396E-5 1.994E-4 2.135E-4 20 673
8 MP:0002145 abnormal T cell differentiation 9.249E-8 2.396E-5 1.994E-4 2.136E-4 16 423
9 MP:0008171 abnormal mature B cell morphology 9.340E-8 2.396E-5 1.994E-4 2.157E-4 19 607
10 MP:0008195 abnormal professional antigen presenting cell morphology 1.537E-7 3.312E-5 2.756E-4 3.548E-4 24 988
11 MP:0005016 decreased lymphocyte cell number 1.659E-7 3.312E-5 2.756E-4 3.830E-4 24 992
12 MP:0002459 abnormal B cell physiology 1.721E-7 3.312E-5 2.756E-4 3.974E-4 19 631
13 MP:0002408 abnormal double-positive T cell morphology 2.042E-7 3.626E-5 3.018E-4 4.714E-4 12 236
14 MP:0002144 abnormal B cell differentiation 2.392E-7 3.945E-5 3.283E-4 5.524E-4 14 340
15 MP:0005092 decreased double-positive T cell number 2.715E-7 4.179E-5 3.478E-4 6.269E-4 11 197
16 MP:0008081 abnormal single-positive T cell number 3.745E-7 5.404E-5 4.497E-4 8.646E-4 9 123
17 MP:0008037 abnormal T cell morphology 4.267E-7 5.795E-5 4.823E-4 9.852E-4 23 964
18 MP:0001806 decreased IgM level 4.600E-7 5.901E-5 4.911E-4 1.062E-3 9 126
19 MP:0002221 abnormal lymph organ size 6.389E-7 7.765E-5 6.462E-4 1.475E-3 23 986
20 MP:0002403 abnormal pre-B cell morphology 7.284E-7 8.410E-5 6.999E-4 1.682E-3 9 133
21 MP:0011086 postnatal lethality, incomplete penetrance 8.187E-7 9.002E-5 7.491E-4 1.890E-3 20 770
22 MP:0010865 prenatal growth retardation 9.349E-7 9.812E-5 8.166E-4 2.159E-3 18 634
23 MP:0005153 abnormal B cell proliferation 9.924E-7 9.962E-5 8.291E-4 2.291E-3 10 179
24 MP:0002444 abnormal T cell physiology 1.500E-6 1.393E-4 1.159E-3 3.464E-3 18 655
25 MP:0020180 abnormal IgM level 1.508E-6 1.393E-4 1.159E-3 3.482E-3 11 234
26 MP:0005093 decreased B cell proliferation 1.829E-6 1.624E-4 1.352E-3 4.223E-3 8 110
27 MP:0013661 abnormal myeloid cell number 2.030E-6 1.716E-4 1.428E-3 4.688E-3 16 532
28 MP:0006387 abnormal T cell number 2.081E-6 1.716E-4 1.428E-3 4.806E-3 21 894
29 MP:0008217 abnormal B cell activation 2.267E-6 1.805E-4 1.502E-3 5.235E-3 10 196
30 MP:0008082 increased single-positive T cell number 2.610E-6 2.008E-4 1.671E-3 6.025E-3 6 52
31 MP:0005018 decreased T cell number 3.230E-6 2.406E-4 2.002E-3 7.458E-3 18 691
32 MP:0003984 embryonic growth retardation 3.524E-6 2.542E-4 2.116E-3 8.136E-3 16 555
33 MP:0002452 abnormal professional antigen presenting cell physiology 5.691E-6 3.982E-4 3.314E-3 1.314E-2 21 952
34 MP:0002490 abnormal immunoglobulin level 6.058E-6 4.114E-4 3.424E-3 1.399E-2 15 511
35 MP:0000701 abnormal lymph node size 6.257E-6 4.128E-4 3.435E-3 1.445E-2 11 271
36 MP:0002460 decreased immunoglobulin level 6.596E-6 4.231E-4 3.521E-3 1.523E-2 12 328
37 MP:0002339 abnormal lymph node morphology 6.973E-6 4.254E-4 3.540E-3 1.610E-2 13 389
38 MP:0005013 increased lymphocyte cell number 7.000E-6 4.254E-4 3.540E-3 1.616E-2 18 730
39 MP:0003111 abnormal cell nucleus morphology 7.465E-6 4.420E-4 3.678E-3 1.724E-2 9 176
40 MP:0008211 decreased mature B cell number 8.257E-6 4.676E-4 3.892E-3 1.907E-2 11 279
41 MP:0012762 abnormal alpha-beta T cell morphology 8.304E-6 4.676E-4 3.892E-3 1.917E-2 18 739
42 MP:0000689 abnormal spleen morphology 8.836E-6 4.679E-4 3.894E-3 2.040E-2 21 979
43 MP:0000715 decreased thymocyte number 8.960E-6 4.679E-4 3.894E-3 2.069E-2 9 180
44 MP:0002407 abnormal double-negative T cell morphology 8.960E-6 4.679E-4 3.894E-3 2.069E-2 9 180
45 MP:0002224 abnormal spleen size 9.119E-6 4.679E-4 3.894E-3 2.106E-2 18 744
46 MP:0006042 increased apoptosis 9.487E-6 4.762E-4 3.963E-3 2.190E-2 19 823
47 MP:0012556 increased cell death 1.017E-5 4.998E-4 4.160E-3 2.349E-2 19 827
48 MP:0000703 abnormal thymus morphology 1.437E-5 6.915E-4 5.755E-3 3.319E-2 15 549
49 MP:0008209 decreased pre-B cell number 1.498E-5 7.059E-4 5.874E-3 3.459E-2 7 105
50 MP:0002435 abnormal effector T cell morphology 1.546E-5 7.079E-4 5.891E-3 3.571E-2 17 697
Show 45 more annotations

6: Domain [Display Chart] 631 annotations before applied cutoff / 16924 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR001473 Clathrin H-chain propeller N InterPro 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
2 G3DSA:2.130.10.110 Clathrin H-chain link/propller Gene3D 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
3 PF01394 Clathrin propel Pfam 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
4 PF09268 Clathrin-link Pfam 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
5 IPR022365 Clathrin H-chain propeller rpt InterPro 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
6 IPR016025 Clathrin H-chain link/propller InterPro 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
7 IPR015348 Clathrin H-chain linker core InterPro 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
8 IPR016341 Clathrin heavy chain InterPro 2.330E-5 1.838E-3 1.291E-2 1.470E-2 2 2
9 G3DSA:1.25.40.30 Clathrin H link Gene3D 6.935E-5 3.978E-3 2.795E-2 4.376E-2 2 3
10 IPR012331 Clathrin H-chain linker InterPro 6.935E-5 3.978E-3 2.795E-2 4.376E-2 2 3
11 SM00299 CLH SMART 6.935E-5 3.978E-3 2.795E-2 4.376E-2 2 3
12 IPR022102 HJURP C InterPro 1.383E-4 6.232E-3 4.378E-2
8.725E-2
 2 4
13 PF12347 HJURP C Pfam 1.383E-4 6.232E-3 4.378E-2
8.725E-2
 2 4
14 IPR000547 Clathrin H-chain/VPS repeat InterPro 1.383E-4 6.232E-3 4.378E-2
8.725E-2
 2 4
15 SM00432 MADS SMART 2.297E-4 8.053E-3
5.658E-2
1.450E-1
 2 5
16 PS50066 MADS BOX 2 PROSITE 2.297E-4 8.053E-3
5.658E-2
1.450E-1
 2 5
17 PS00350 MADS BOX 1 PROSITE 2.297E-4 8.053E-3
5.658E-2
1.450E-1
 2 5
18 PF00319 SRF-TF Pfam 2.297E-4 8.053E-3
5.658E-2
1.450E-1
 2 5
19 IPR018525 DNA-dep ATPase MCM CS InterPro 3.435E-4 1.084E-2
7.614E-2
2.167E-1
 2 6
20 IPR002100 TF MADSbox InterPro 3.435E-4 1.084E-2
7.614E-2
2.167E-1
 2 6
21 PF10401 IRF-3 Pfam 4.794E-4 1.375E-2
9.660E-2
3.025E-1
 2 7
22 IPR019471 Interferon reg factor-3 InterPro 4.794E-4 1.375E-2
9.660E-2
3.025E-1
 2 7
23 PS50051 MCM 2 PROSITE 6.372E-4 1.520E-2
1.068E-1
4.021E-1
 2 8
24 SM00350 MCM SMART 6.372E-4 1.520E-2
1.068E-1
4.021E-1
 2 8
25 PS00847 MCM 1 PROSITE 6.372E-4 1.520E-2
1.068E-1
4.021E-1
 2 8
26 IPR001208 DNA-dep ATPase MCM InterPro 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
27 IPR019817 Interferon reg fac CS InterPro 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
28 PS51507 IRF 2 PROSITE 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
29 PF00493 MCM Pfam 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
30 SM00348 IRF SMART 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
31 PS00601 IRF 1 PROSITE 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
32 IPR001346 Interferon reg factor InterPro 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
33 PF00605 IRF Pfam 8.166E-4 1.520E-2
1.068E-1
5.153E-1
 2 9
34 IPR009057 Homeodomain-like InterPro 8.189E-4 1.520E-2
1.068E-1
5.167E-1
 7 314
35 IPR014400 Cyclin A B D E InterPro 1.240E-3 2.235E-2
1.570E-1
7.823E-1
 2 11
36 PF00010 HLH Pfam 1.872E-3 3.032E-2
2.130E-1
1.000E0
 4 108
37 PS00036 BZIP BASIC PROSITE 2.042E-3 3.032E-2
2.130E-1
1.000E0
 3 52
38 SM00338 BRLZ SMART 2.042E-3 3.032E-2
2.130E-1
1.000E0
 3 52
39 IPR004827 TF bZIP InterPro 2.157E-3 3.032E-2
2.130E-1
1.000E0
 3 53
40 PS50217 BZIP PROSITE 2.157E-3 3.032E-2
2.130E-1
1.000E0
 3 53
41 PS50888 HLH PROSITE 2.209E-3 3.032E-2
2.130E-1
1.000E0
 4 113
42 G3DSA:4.10.280.10 HLH DNA bd Gene3D 2.209E-3 3.032E-2
2.130E-1
1.000E0
 4 113
43 SM00353 HLH SMART 2.281E-3 3.032E-2
2.130E-1
1.000E0
 4 114
44 PF02984 Cyclin C Pfam 2.337E-3 3.032E-2
2.130E-1
1.000E0
 2 15
45 IPR004367 Cyclin C InterPro 2.337E-3 3.032E-2
2.130E-1
1.000E0
 2 15
46 IPR011598 HLH DNA-bd InterPro 2.354E-3 3.032E-2
2.130E-1
1.000E0
 4 115
47 G3DSA:1.10.10.60 Homeodomain-rel Gene3D 2.421E-3 3.032E-2
2.130E-1
1.000E0
 6 281
48 IPR001092 HLH DNA-bd dom InterPro 2.429E-3 3.032E-2
2.130E-1
1.000E0
 4 116
49 IPR012287 Homeodomain-rel InterPro 2.508E-3 3.032E-2
2.130E-1
1.000E0
 6 283
50 IPR017855 SMAD dom-like InterPro 2.663E-3 3.032E-2
2.130E-1
1.000E0
 2 16
Show 45 more annotations

7: Pathway [Display Chart] 695 annotations before applied cutoff / 10916 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 198774 TGF-beta Receptor Signaling Pathway BioSystems: WikiPathways 9.914E-6 4.993E-3 3.556E-2 6.890E-3 8 154
2 198907 Energy Metabolism BioSystems: WikiPathways 1.819E-5 4.993E-3 3.556E-2 1.264E-2 5 48
3 83054 Cell cycle BioSystems: KEGG 2.155E-5 4.993E-3 3.556E-2 1.498E-2 7 124
4 138006 ATF-2 transcription factor network BioSystems: Pathway Interaction Database 3.561E-5 6.187E-3 4.406E-2 2.475E-2 5 55
5 169349 Validated transcriptional targets of AP1 family members Fra1 and Fra2 BioSystems: Pathway Interaction Database 8.154E-5 1.066E-2
7.594E-2
5.667E-2
 4 34
6 198805 G1 to S cell cycle control BioSystems: WikiPathways 9.955E-5 1.066E-2
7.594E-2
6.918E-2
 5 68
7 187098 TRAF3-dependent IRF activation pathway BioSystems: REACTOME 1.074E-4 1.066E-2
7.594E-2
7.464E-2
 3 14
8 138073 C-MYB transcription factor network BioSystems: Pathway Interaction Database 1.911E-4 1.587E-2
1.130E-1
1.328E-1
 5 78
9 523016 Transcriptional misregulation in cancer BioSystems: KEGG 2.200E-4 1.587E-2
1.130E-1
1.529E-1
 7 179
10 169351 Validated targets of C-MYC transcriptional activation BioSystems: Pathway Interaction Database 2.283E-4 1.587E-2
1.130E-1
1.587E-1
 5 81
11 198828 Hypertrophy Model BioSystems: WikiPathways 3.265E-4 2.063E-2
1.469E-1
2.269E-1
 3 20
12 198871 Id Signaling Pathway BioSystems: WikiPathways 4.336E-4 2.457E-2
1.750E-1
3.013E-1
 4 52
13 833821 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production BioSystems: REACTOME 4.596E-4 2.457E-2
1.750E-1
3.194E-1
 2 5
14 105765 Cell Cycle, Mitotic BioSystems: REACTOME 5.237E-4 2.600E-2
1.852E-1
3.640E-1
 10 416
15 M8560 Cell Cycle: G2/M Checkpoint MSigDB C2 BIOCARTA (v5.1) 5.684E-4 2.633E-2
1.876E-1
3.950E-1
 3 24
16 198811 Cell cycle BioSystems: WikiPathways 6.637E-4 2.883E-2
2.053E-1
4.613E-1
 5 102
17 530733 Cell Cycle BioSystems: REACTOME 7.193E-4 2.941E-2
2.094E-1
4.999E-1
 11 514
18 169353 Validated targets of C-MYC transcriptional repression BioSystems: Pathway Interaction Database 8.483E-4 3.275E-2
2.333E-1
5.896E-1
 4 62
19 138045 HIF-1-alpha transcription factor network BioSystems: Pathway Interaction Database 1.014E-3 3.708E-2
2.641E-1
7.045E-1
 4 65
20 198868 AMPK signaling BioSystems: WikiPathways 1.201E-3 3.852E-2
2.744E-1
8.344E-1
 4 68
21 160998 CDO in myogenesis BioSystems: REACTOME 1.219E-3 3.852E-2
2.744E-1
8.475E-1
 3 31
22 160997 Myogenesis BioSystems: REACTOME 1.219E-3 3.852E-2
2.744E-1
8.475E-1
 3 31
23 187100 TRAF6 mediated IRF7 activation BioSystems: REACTOME 1.339E-3 4.046E-2
2.882E-1
9.306E-1
 3 32
24 137934 E2F transcription factor network BioSystems: Pathway Interaction Database 1.564E-3 4.172E-2
2.972E-1
1.000E0
 4 73
25 645263 Regulation of Gene Expression by Hypoxia-inducible Factor BioSystems: REACTOME 1.625E-3 4.172E-2
2.972E-1
1.000E0
 2 9
26 SMP00383 Obesity / Metabolic Syndrome SMPDB 1.625E-3 4.172E-2
2.972E-1
1.000E0
 2 9
27 105934 Formation of annular gap junctions BioSystems: REACTOME 1.625E-3 4.172E-2
2.972E-1
1.000E0
 2 9
28 138012 Signaling mediated by p38-alpha and p38-beta BioSystems: Pathway Interaction Database 1.741E-3 4.172E-2
2.972E-1
1.000E0
 3 35
29 M2499 CARM1 and Regulation of the Estrogen Receptor MSigDB C2 BIOCARTA (v5.1) 1.741E-3 4.172E-2
2.972E-1
1.000E0
 3 35
30 137963 Regulation of nuclear SMAD2/3 signaling BioSystems: Pathway Interaction Database 1.997E-3 4.535E-2
3.229E-1
1.000E0
 4 78
31 105933 Gap junction degradation BioSystems: REACTOME 2.023E-3 4.535E-2
3.229E-1
1.000E0
 2 10
32 198832 Adipogenesis BioSystems: WikiPathways 2.172E-3 4.718E-2
3.360E-1
1.000E0
 5 133
Show 27 more annotations

8: Pubmed [Display Chart] 20977 annotations before applied cutoff / 51818 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 25609649 Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes. Pubmed 9.310E-17 1.953E-12 2.056E-11 1.953E-12 19 849
2 21424034 B-cell transcription factors Pax-5, Oct-2, BOB.1, Bcl-6, and MUM1 are useful markers for the diagnosis of nodular lymphocyte predominant Hodgkin lymphoma. Pubmed 3.055E-11 3.204E-7 3.374E-6 6.409E-7 4 5
3 19692168 Genetic susceptibility to distinct bladder cancer subphenotypes. Pubmed 8.761E-11 4.594E-7 4.837E-6 1.838E-6 11 422
4 19692168:gr Genetic susceptibility to distinct bladder cancer subphenotypes. GeneRIF 8.761E-11 4.594E-7 4.837E-6 1.838E-6 11 422
5 19738201 Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6. Pubmed 1.142E-10 4.791E-7 5.045E-6 2.396E-6 13 708
6 23455922 Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. Pubmed 1.610E-10 5.629E-7 5.926E-6 3.377E-6 11 447
7 19625176 PTEN identified as important risk factor of chronic obstructive pulmonary disease. Pubmed 5.458E-10 1.368E-6 1.440E-5 1.145E-5 10 376
8 19625176:gr PTEN identified as important risk factor of chronic obstructive pulmonary disease. GeneRIF 5.458E-10 1.368E-6 1.440E-5 1.145E-5 10 376
9 19170196 Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. Pubmed 6.520E-10 1.368E-6 1.440E-5 1.368E-5 10 383
10 19170196:gr Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. GeneRIF 6.520E-10 1.368E-6 1.440E-5 1.368E-5 10 383
11 15796964:gr Alterations of loci encoding PU.1, BOB1, and OCT2 transcription regulators do not correlate with their suppressed expression in Hodgkin lymphoma. GeneRIF 3.969E-9 6.937E-6 7.304E-5 8.325E-5 3 3
12 15796964 Alterations of loci encoding PU.1, BOB1, and OCT2 transcription regulators do not correlate with their suppressed expression in Hodgkin lymphoma. Pubmed 3.969E-9 6.937E-6 7.304E-5 8.325E-5 3 3
13 16964243 A probability-based approach for high-throughput protein phosphorylation analysis and site localization. Pubmed 8.776E-9 1.416E-5 1.491E-4 1.841E-4 10 503
14 22990118 Charting the landscape of tandem BRCT domain-mediated protein interactions. Pubmed 1.116E-8 1.525E-5 1.606E-4 2.340E-4 11 672
15 18676680 Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. Pubmed 1.164E-8 1.525E-5 1.606E-4 2.441E-4 9 381
16 18676680:gr Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. GeneRIF 1.164E-8 1.525E-5 1.606E-4 2.441E-4 9 381
17 12054881 Immunoprecipitation techniques for the analysis of transcription factor complexes. Pubmed 1.583E-8 1.581E-5 1.665E-4 3.321E-4 3 4
18 20064451:gr Analysis of interleukin-21-induced Prdm1 gene regulation reveals functional cooperation of STAT3 and IRF4 transcription factors. GeneRIF 1.583E-8 1.581E-5 1.665E-4 3.321E-4 3 4
19 19955181 Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways. Pubmed 1.583E-8 1.581E-5 1.665E-4 3.321E-4 3 4
20 23045607:gr B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. GeneRIF 1.583E-8 1.581E-5 1.665E-4 3.321E-4 3 4
21 19955181:gr Human T cell lymphotropic virus 1 manipulates interferon regulatory signals by controlling the TAK1-IRF3 and IRF4 pathways. GeneRIF 1.583E-8 1.581E-5 1.665E-4 3.321E-4 3 4
22 25852190 Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy. Pubmed 1.806E-8 1.722E-5 1.813E-4 3.788E-4 9 401
23 24163370 The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. Pubmed 1.984E-8 1.809E-5 1.905E-4 4.161E-4 8 283
24 21423176 Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for ß-Pix in negative regulation of focal adhesion maturation. Pubmed 2.152E-8 1.881E-5 1.981E-4 4.515E-4 8 286
25 20808282 A multiprotein complex necessary for both transcription and DNA replication at the ß-globin locus. Pubmed 3.586E-8 2.766E-5 2.912E-4 7.523E-4 4 21
26 25468996 E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Pubmed 3.718E-8 2.766E-5 2.912E-4 7.799E-4 8 307
27 15302918 TIP27: a novel repressor of the nuclear orphan receptor TAK1/TR4. Pubmed 3.953E-8 2.766E-5 2.912E-4 8.293E-4 3 5
28 21424034:gr B-cell transcription factors Pax-5, Oct-2, BOB.1, Bcl-6, and MUM1 are useful markers for the diagnosis of nodular lymphocyte predominant Hodgkin lymphoma. GeneRIF 3.953E-8 2.766E-5 2.912E-4 8.293E-4 3 5
29 18977241 Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. Pubmed 4.012E-8 2.766E-5 2.912E-4 8.416E-4 6 118
30 18977241:gr Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. GeneRIF 4.012E-8 2.766E-5 2.912E-4 8.416E-4 6 118
31 17601350 A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. Pubmed 4.219E-8 2.766E-5 2.912E-4 8.851E-4 6 119
32 17601350:gr A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. GeneRIF 4.219E-8 2.766E-5 2.912E-4 8.851E-4 6 119
33 20936779 A human MAP kinase interactome. Pubmed 9.277E-8 5.897E-5 6.209E-4 1.946E-3 9 486
34 22586326 Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription. Pubmed 1.005E-7 6.198E-5 6.525E-4 2.107E-3 10 653
35 23125841 Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1. Pubmed 1.326E-7 7.947E-5 8.367E-4 2.781E-3 7 241
36 23602568 The protein interaction landscape of the human CMGC kinase group. Pubmed 1.759E-7 1.025E-4 1.079E-3 3.690E-3 10 694
37 15635413 Nucleolar proteome dynamics. Pubmed 3.972E-7 2.252E-4 2.371E-3 8.332E-3 8 419
38 24999758 Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. Pubmed 4.421E-7 2.440E-4 2.569E-3 9.273E-3 8 425
39 15302935 Large-scale characterization of HeLa cell nuclear phosphoproteins. Pubmed 4.701E-7 2.529E-4 2.662E-3 9.862E-3 10 773
40 20562859 Network organization of the human autophagy system. Pubmed 4.998E-7 2.621E-4 2.760E-3 1.048E-2 8 432
41 19275580 HIV-1 Vpr: a closer look at the multifunctional protein from the structural perspective. Pubmed 8.627E-7 4.414E-4 4.647E-3 1.810E-2 3 12
42 23443559 LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells. Pubmed 9.106E-7 4.548E-4 4.788E-3 1.910E-2 9 639
43 25963833 Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage. Pubmed 1.049E-6 4.886E-4 5.144E-3 2.201E-2 10 845
44 21044950 Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells. Pubmed 1.093E-6 4.886E-4 5.144E-3 2.294E-2 7 330
45 20453000:gr A Large-scale genetic association study of esophageal adenocarcinoma risk. GeneRIF 1.646E-6 4.886E-4 5.144E-3 3.452E-2 7 351
46 20453000 A Large-scale genetic association study of esophageal adenocarcinoma risk. Pubmed 1.646E-6 4.886E-4 5.144E-3 3.452E-2 7 351
47 21048031:gr Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. GeneRIF 2.190E-6 4.886E-4 5.144E-3 4.595E-2 6 233
48 21048031 Single nucleotide polymorphisms of matrix metalloproteinase 9 (MMP9) and tumor protein 73 (TP73) interact with Epstein-Barr virus in chronic lymphocytic leukemia: results from the European case-control study EpiLymph. Pubmed 2.190E-6 4.886E-4 5.144E-3 4.595E-2 6 233
49 26641092 The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells. Pubmed 2.536E-6 4.886E-4 5.144E-3
5.320E-2
 6 239
50 17682124:gr Human BSAP and BLIMP1 conform an autoregulatory feedback loop. GeneRIF 2.539E-6 4.886E-4 5.144E-3
5.326E-2
 2 2
Show 45 more annotations

9: Interaction [Display Chart] 4759 annotations before applied cutoff / 16535 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:EP300 EP300 interactions 2.439E-16 1.160E-12 1.050E-11 1.160E-12 23 501
2 int:SMAD2 SMAD2 interactions 1.695E-11 4.033E-8 3.648E-7 8.066E-8 15 295
3 int:TBP TBP interactions 1.149E-10 1.823E-7 1.649E-6 5.469E-7 12 183
4 int:RB1 RB1 interactions 3.785E-10 4.503E-7 4.073E-6 1.801E-6 13 253
5 int:GATA2 GATA2 interactions 2.414E-9 2.298E-6 2.078E-5 1.149E-5 7 45
6 int:JUND JUND interactions 3.319E-9 2.607E-6 2.358E-5 1.579E-5 7 47
7 int:CREBBP CREBBP interactions 4.177E-9 2.607E-6 2.358E-5 1.988E-5 14 371
8 int:CDK2 CDK2 interactions 4.382E-9 2.607E-6 2.358E-5 2.085E-5 18 670
9 int:ASCL1 ASCL1 interactions 5.450E-9 2.882E-6 2.607E-5 2.594E-5 5 14
10 int:CASP3 CASP3 interactions 2.112E-8 1.005E-5 9.091E-5 1.005E-4 10 179
11 int:CEBPA CEBPA interactions 9.999E-8 3.751E-5 3.393E-4 4.759E-4 10 211
12 int:CDK1 CDK1 interactions 1.025E-7 3.751E-5 3.393E-4 4.877E-4 11 270
13 int:HIST1H3A HIST1H3A interactions 1.025E-7 3.751E-5 3.393E-4 4.877E-4 11 270
14 int:ID3 ID3 interactions 1.213E-7 4.123E-5 3.730E-4 5.773E-4 6 47
15 int:HDAC5 HDAC5 interactions 1.737E-7 5.512E-5 4.986E-4 8.268E-4 12 351
16 int:CDKN1B CDKN1B interactions 2.423E-7 6.783E-5 6.136E-4 1.153E-3 7 86
17 int:NCOA2 NCOA2 interactions 2.423E-7 6.783E-5 6.136E-4 1.153E-3 7 86
18 int:TERF1 TERF1 interactions 4.228E-7 1.118E-4 1.011E-3 2.012E-3 11 311
19 int:CEBPB CEBPB interactions 4.470E-7 1.120E-4 1.013E-3 2.127E-3 7 94
20 int:SMARCA4 SMARCA4 interactions 4.999E-7 1.157E-4 1.047E-3 2.379E-3 10 251
21 int:PRDM1 PRDM1 interactions 5.107E-7 1.157E-4 1.047E-3 2.431E-3 5 32
22 int:HDAC4 HDAC4 interactions 6.525E-7 1.353E-4 1.223E-3 3.105E-3 8 145
23 int:AKT1 AKT1 interactions 6.537E-7 1.353E-4 1.223E-3 3.111E-3 11 325
24 int:RUNX1 RUNX1 interactions 6.823E-7 1.353E-4 1.224E-3 3.247E-3 7 100
25 int:EPAS1 EPAS1 interactions 8.910E-7 1.696E-4 1.534E-3 4.240E-3 7 104
26 int:ESR1 ESR1 interactions 9.454E-7 1.730E-4 1.565E-3 4.499E-3 16 758
27 int:MECP2 MECP2 interactions 1.041E-6 1.769E-4 1.600E-3 4.953E-3 6 67
28 int:ETS1 ETS1 interactions 1.041E-6 1.769E-4 1.600E-3 4.953E-3 6 67
29 int:PCNA PCNA interactions 2.163E-6 3.549E-4 3.210E-3 1.029E-2 10 295
30 int:SKP2 SKP2 interactions 2.339E-6 3.704E-4 3.350E-3 1.113E-2 7 120
31 int:JAZF1 JAZF1 interactions 2.413E-6 3.704E-4 3.350E-3 1.148E-2 3 6
32 int:BRCA1 BRCA1 interactions 2.944E-6 4.326E-4 3.913E-3 1.401E-2 13 544
33 int:MAPK1 MAPK1 interactions 3.000E-6 4.326E-4 3.913E-3 1.427E-2 10 306
34 int:BATF BATF interactions 3.310E-6 4.633E-4 4.191E-3 1.575E-2 4 21
35 int:RBL1 RBL1 interactions 3.440E-6 4.677E-4 4.231E-3 1.637E-2 6 82
36 int:TAF4 TAF4 interactions 6.701E-6 8.859E-4 8.013E-3 3.189E-2 5 53
37 int:TP53BP1 TP53BP1 interactions 7.493E-6 9.549E-4 8.637E-3 3.566E-2 7 143
38 int:TFAP4 TFAP4 interactions 7.624E-6 9.549E-4 8.637E-3 3.628E-2 6 94
39 int:TLE4 TLE4 interactions 8.111E-6 9.898E-4 8.953E-3 3.860E-2 4 26
40 int:XRCC6 XRCC6 interactions 9.582E-6 1.140E-3 1.031E-2 4.560E-2 9 275
41 int:MYOD1 MYOD1 interactions 1.029E-5 1.189E-3 1.075E-2 4.895E-2 6 99
42 int:MEF2A MEF2A interactions 1.049E-5 1.189E-3 1.075E-2 4.993E-2 5 58
43 int:ATF3 ATF3 interactions 1.578E-5 1.648E-3 1.491E-2
7.511E-2
 5 63
44 int:UBE2I UBE2I interactions 1.579E-5 1.648E-3 1.491E-2
7.515E-2
 11 453
45 int:ATR ATR interactions 1.607E-5 1.648E-3 1.491E-2
7.647E-2
 6 107
46 int:CCDC8 CCDC8 interactions 1.643E-5 1.648E-3 1.491E-2
7.818E-2
 12 544
47 int:HDAC3 HDAC3 interactions 1.650E-5 1.648E-3 1.491E-2
7.850E-2
 8 224
48 int:SMAD3 SMAD3 interactions 1.663E-5 1.648E-3 1.491E-2
7.913E-2
 10 372
49 int:CCND1 CCND1 interactions 1.786E-5 1.735E-3 1.569E-2
8.500E-2
 6 109
50 int:ID2 ID2 interactions 1.840E-5 1.740E-3 1.574E-2
8.757E-2
 5 65
Show 45 more annotations

10: Cytoband [Display Chart] 75 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 5p12 5p12 1.640E-3 3.000E-2
1.471E-1
1.230E-1
 2 25
2 12q13.1-q13.2 12q13.1-q13.2 2.400E-3 3.000E-2
1.471E-1
1.800E-1
 1 1
3 1p36.13-p36.12 1p36.13-p36.12 2.400E-3 3.000E-2
1.471E-1
1.800E-1
 1 1
4 6p25-p23 6p25-p23 2.400E-3 3.000E-2
1.471E-1
1.800E-1
 1 1
5 7p15.2-p15.1 7p15.2-p15.1 2.400E-3 3.000E-2
1.471E-1
1.800E-1
 1 1
6 16q21-q22.3 16q21-q22.3 2.400E-3 3.000E-2
1.471E-1
1.800E-1
 1 1
7 19q13 19q13 3.024E-3 3.240E-2
1.588E-1
2.268E-1
 2 34
8 2q12-q21 2q12-q21 4.784E-3 4.485E-2
2.198E-1
3.588E-1
 1 2
Show 3 more annotations

11: Transcription Factor Binding Site [Display Chart] 496 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$SREBP1 02 V$SREBP1 02 5.041E-6 2.500E-3 1.696E-2 2.500E-3 6 74
2 V$ETS2 B V$ETS2 B 4.803E-5 1.191E-2
8.082E-2
 2.382E-2 8 220
3 V$EGR1 01 V$EGR1 01 1.937E-4 2.718E-2
1.844E-1
9.607E-2
 7 201
4 CTTTAAR UNKNOWN CTTTAAR UNKNOWN 2.192E-4 2.718E-2
1.844E-1
1.087E-1
 14 799
5 ACAWNRNSRCGG UNKNOWN ACAWNRNSRCGG UNKNOWN 3.029E-4 3.005E-2
2.039E-1
1.502E-1
 4 54
6 TAANNYSGCG UNKNOWN TAANNYSGCG UNKNOWN 5.479E-4 4.529E-2
3.073E-1
2.718E-1
 4 63
Show 1 more annotation

12: Gene Family [Display Chart] 13 annotations before applied cutoff / 6751 genes in category

No results to display

13: Coexpression [Display Chart] 5287 annotations before applied cutoff / 21867 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M9150 Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.237E-12 6.541E-9 5.985E-8 6.541E-9 15 323
2 M12804 Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.900E-9 2.088E-5 1.911E-4 4.177E-5 8 108
3 M9516 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of BRCA2 [GeneID=675] across a compendium of normal tissues. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.592E-8 8.548E-5 7.822E-4 3.485E-4 12 423
4 M6506 Genes up-regulated by MYC [GeneID=4609] and whose promoters are bound by MYC, according to MYC Target Gene Database. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.165E-8 8.548E-5 7.822E-4 3.788E-4 8 143
5 M16336 Up-regulated genes in MM1.S cells (multiple myeloma) treated with adaphostin [PubChem=387042], a tyrosine kinase inhibitor with anticancer properties. MSigDB C2: CGP Curated Gene Sets (v5.1) 8.875E-8 8.548E-5 7.822E-4 4.692E-4 8 147
6 M7623 Genes down-regulated in multiple myeloma (MM) cell lines treated with both decitabine [PubChem=451668] TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.115E-7 8.548E-5 7.822E-4 5.893E-4 10 281
7 M1577 Strongly up-regulated at 16-24 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.132E-7 8.548E-5 7.822E-4 5.984E-4 7 101
8 M11318 Genes down-regulated in the MM1S cells (multiple myeloma) after treatment with aplidin [PubChem=44152164], a marine-derived compound with potential anti-cancer properties. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.398E-7 2.796E-4 2.558E-3 2.325E-3 9 249
9 M16458 Selected gradually up-regulated genes in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). MSigDB C2: CGP Curated Gene Sets (v5.1) 4.759E-7 2.796E-4 2.558E-3 2.516E-3 6 77
10 M7079 The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.628E-7 2.975E-4 2.722E-3 2.975E-3 10 335
11 M5292 Genes down-regulated in comparison of untreated CD4 [GeneID=920] memory T cells from young donors versus those treated with TSST at 40 h. MSigDB C7: Immunologic Signatures (v5.1) 9.336E-7 4.181E-4 3.826E-3 4.936E-3 8 200
12 M8156 Genes showing cell-cycle stage-specific expression [PMID=12058064]. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.491E-7 4.181E-4 3.826E-3 5.018E-3 13 648
13 M27 Set 'Myc targets1': targets of c-Myc [GeneID=4609] identified by ChIP on chip in cultured cell lines, focusing on E-box-containing genes; high affinity bound subset MSigDB C2: CGP Curated Gene Sets (v5.1) 2.655E-6 1.080E-3 9.880E-3 1.404E-2 8 230
14 M1384 Cluster 2 of genes distinguishing among different B lymphocyte neoplasms. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.905E-6 1.763E-3 1.613E-2 2.593E-2 4 30
15 M6324 Genes down-regulated in untreated spleen: DUSP1 [GeneID=1843] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v5.1) 5.001E-6 1.763E-3 1.613E-2 2.644E-2 7 177
16 M14718 Examples of transcription factors whose activities are regulated by MAPK14 [GeneID=1432] phosphorylation. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.207E-6 2.047E-3 1.873E-2 3.282E-2 3 10
17 M11884 Genes up-regulated at the peak of an antigen response of naive CD8+ [GeneID=925;926] T-cells. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.580E-6 2.047E-3 1.873E-2 3.479E-2 9 346
18 M14591 Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to HNE, tBH and H2O2 [PubChem=5283344;6410;784]. MSigDB C2: CGP Curated Gene Sets (v5.1) 9.236E-6 2.352E-3 2.152E-2 4.883E-2 4 35
19 M5169 Genes down-regulated in comparison of macrophages versus macrophages exposed to B. malayi (5 worms/well). MSigDB C7: Immunologic Signatures (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
20 GSE28726 NAIVE VS ACTIVATED CD4 TCELL DN Genes down-regulated in CD4 [GeneID=920] T cells: naïve versus activated. MSigDB C7: Immunologic Signatures (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
21 GSE33425 CD161 HIGH VS INT CD8 TCELL UP Genes up-regulated in CD8 T cells: KLRB1 high [GeneID=3820] versus KLRB1 int [GeneID=3820]. MSigDB C7: Immunologic Signatures (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
22 M3237 Genes down-regulated in comparison of memory CD4 [GeneID=920] T cells treated with retinoic acid (tretinoin) [PubChem=444795] versus untreated memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
23 M5925 Genes encoding cell cycle related targets of E2F transcription factors. MSigDB H: Hallmark Gene Sets (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
24 GSE21360 PRIMARY VS TERTIARY MEMORY CD8 TCELL UP Genes up-regulated in memory CD8 T cells: 1' versus 3'. MSigDB C7: Immunologic Signatures (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
25 M3597 Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 48 h. MSigDB C7: Immunologic Signatures (v5.1) 1.112E-5 2.352E-3 2.152E-2
5.879E-2
 7 200
26 M14665 Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.324E-5 2.693E-3 2.464E-2
7.002E-2
 10 478
27 M11594 Amplification hot spot 22: colocolized fragile sites and cancer genes in the 22q11.1-q13s region. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.467E-5 2.873E-3 2.629E-2
7.757E-2
 3 13
28 M1681 Cluster 4: genes maximally expressed at 16 h time point during differentiation of 3T3-L1 fibroblasts into adipocytes in response to adipogenic hormones. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.589E-5 3.000E-3 2.745E-2
8.401E-2
 4 40
29 M4371 Genes up-regulated in mice with skin specific knockout of TP53 [GeneID=7157]. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.684E-5 3.071E-3 2.810E-2
8.905E-2
 11 602
30 M802 Selected gradually up-regulated genes whose expression profile follows that of HBZ [GeneID=3050] in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts). MSigDB C2: CGP Curated Gene Sets (v5.1) 1.756E-5 3.075E-3 2.814E-2
9.283E-2
 4 41
31 M2606 Cell cycle genes significantly (p =< 0.05) changed in fibroblast cells at 6 h after exposure to ionizing radiation. MSigDB C2: CGP Curated Gene Sets (v5.1) 1.803E-5 3.075E-3 2.814E-2
9.532E-2
 5 85
32 M1591 Cluster 5: genes progressively up-regulated (peak at 24 h time point) during differentiation of 3T3-L1 fibroblasts into adipocytes in response to adipogenic hormones. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.127E-5 3.515E-3 3.216E-2
1.125E-1
 4 43
33 M2375 Down-regulated in B lymphocytes from patients with ICF syndrom caused by mutations in DNMT3B [GeneID=1789] compared to normals. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.322E-5 3.719E-3 3.403E-2
1.227E-1
 3 15
34 M2569 Genes changed in pre-B lymphoblastic leukemia cells with BCR-ABL1 fusion [GeneID=613, 25] vs normal pre-B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v5.1) 2.554E-5 3.971E-3 3.633E-2
1.350E-1
 4 45
35 M16189 Genes up-regulated in NIH3T3 cells (fibroblasts) transformed by expression of contitutively active (Q63L) form of RHOA [GeneID=387] off plasmid vector. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.522E-5 5.152E-3 4.715E-2
1.862E-1
 10 536
36 M18506 Genes down-regulated in the ANBL-6 cell line (multiple myeloma, MM) after withdrawal of IL6 [GeneID=3569]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.592E-5 5.152E-3 4.715E-2
1.899E-1
 5 98
37 M11961 Genes constituting the CHEK2-PCC network of transcripts whose expression positively correlates (Pearson correlation coefficient, PCC >= 0.4) with that of CHEK2 [GeneID=11200]. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.606E-5 5.152E-3 4.715E-2
1.906E-1
 12 778
38 M19693 Genes up-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. MSigDB C2: CGP Curated Gene Sets (v5.1) 3.990E-5 5.551E-3
5.079E-2
2.109E-1
 7 244
39 M18811 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200] in a compendium of normal tissues. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.353E-5 5.901E-3
5.400E-2
2.301E-1
 6 168
40 M11829 Genes up-regulated by adenoviral expression of c-MYC [GeneID=4609] in HUVEC cells (umbilical vein endothelium). MSigDB C2: CGP Curated Gene Sets (v5.1) 4.904E-5 6.324E-3
5.787E-2
2.593E-1
 4 53
41 M1945 Genes up-regulated in MEF cells (embryonic fibroblast) after expression of E2F1 or E2F2 [GeneID=1869;1870]. MSigDB C2: CGP Curated Gene Sets (v5.1) 4.904E-5 6.324E-3
5.787E-2
2.593E-1
 4 53
42 M6782 Genes up-regulated in T24 (bladder cancer) cells in response to the photodynamic therapy (PDT) stress. MSigDB C2: CGP Curated Gene Sets (v5.1) 5.386E-5 6.780E-3
6.204E-2
2.848E-1
 12 811
43 M19492 Genes exclusively down-regulated in B lymphocytes from CLL (chronic lymphocytic leukemia) patients but with a similiar expression pattern in the normal cells and in the cells from WM (Waldenstroem's macroblobulinemia) patients. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.098E-5 7.274E-3
6.656E-2
3.224E-1
 4 56
44 GSE14415 NATURAL TREG VS TCONV DN Genes down-regulated in natural T reg versus T conv. MSigDB C7: Immunologic Signatures (v5.1) 6.390E-5 7.274E-3
6.656E-2
3.378E-1
 6 180
45 M1218 Genes up-regulated in hepatocellular carcinoma (HCC) developed by transgenic mice overexpressing a secretable form of EGF [GeneID=1950] in liver. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.540E-5 7.274E-3
6.656E-2
3.457E-1
 4 57
46 M3456 Genes identified by ChIP within the high-affinity group of MYC [GeneID=4609] targets. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.794E-5 7.274E-3
6.656E-2
3.592E-1
 6 182
47 M1859 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. MSigDB C2: CGP Curated Gene Sets (v5.1) 6.990E-5 7.274E-3
6.656E-2
3.695E-1
 8 362
48 M12661 Genes commonly down-regulated in SK-N-BE cells (neuroblastoma) after RNAi knockdown of CCND1 and CDK4 [GeneID=595;1019]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.004E-5 7.274E-3
6.656E-2
3.703E-1
 4 58
49 M9402 Cell cycle genes down-regulated in H1299 cells (lung cancer) after overexpression of either P53 or P73 [GeneID=7157;7161]. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.708E-5 7.274E-3
6.656E-2
4.075E-1
 3 22
50 M16431 Genes up-regulated in T-PLL cells (T-cell prolymphocytic leukemia) bearing the inv(14)/t(14:14) chromosomal aberration. MSigDB C2: CGP Curated Gene Sets (v5.1) 7.838E-5 7.274E-3
6.656E-2
4.144E-1
 8 368
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 2182 annotations before applied cutoff / 20974 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 fetal replicating Top 500 All fetal replicating Top 500 All Brain Map - Barres 8.477E-9 1.850E-5 1.529E-4 1.850E-5 14 496
2 GSM538352 500 B cells, proB.FrA.BM, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Bone marrow, avg-2 Immgen.org, GSE15907 3.693E-7 4.029E-4 3.330E-3 8.057E-4 11 388
3 gudmap developingGonad e11.5 testes and mesonephros 1000 DevelopingGonad e11.5 testes and mesonephros emap-3226 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 9.809E-7 7.134E-4 5.897E-3 2.140E-3 15 844
4 gudmap developingGonad e12.5 testes 1000 DevelopingGonad e12.5 testes emap-29069 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.711E-6 1.556E-3 1.286E-2 8.098E-3 14 819
5 GSM538358 500 B cells, proB.FrBC.FL, CD19+ IgM- CD43+ CD24+ AA4.1+ CD45R+, Fetal Liver, avg-3 Immgen.org, GSE15907 4.008E-6 1.556E-3 1.286E-2 8.744E-3 10 400
6 GSM399452 500 B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3 Immgen.org, GSE15907 4.877E-6 1.556E-3 1.286E-2 1.064E-2 10 409
7 GSM476664 500 gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3 Immgen.org, GSE15907 6.031E-6 1.556E-3 1.286E-2 1.316E-2 10 419
8 GSM538355 500 B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R+ CD, Fetal Liver, avg-2 Immgen.org, GSE15907 6.420E-6 1.556E-3 1.286E-2 1.401E-2 10 422
9 GSM538357 500 B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Fetal Liver, avg-1 Immgen.org, GSE15907 6.420E-6 1.556E-3 1.286E-2 1.401E-2 10 422
10 GSM538418 500 B cells, proB.FrBC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-1 Immgen.org, GSE15907 1.813E-5 3.828E-3 3.164E-2 3.956E-2 9 377
11 GSM538207 500 B cells, B.GC.Sp, CD19+ IgM+ IgD- GL7+ PNA+, Spleen, avg-3 Immgen.org, GSE15907 1.930E-5 3.828E-3 3.164E-2 4.211E-2 9 380
12 gudmap developingGonad e11.5 testes 1000 DevelopingGonad e11.5 testes emap-3226 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.551E-5 4.638E-3 3.833E-2
5.566E-2
 13 843
13 GSM791114 500 Stem Cells, SC.CDP.BM, Sca1- Flt3+ MCSFR+ cKitlo, Bone marrow, avg-3 Immgen.org, GSE15907 2.943E-5 4.678E-3 3.866E-2
6.423E-2
 9 401
14 GSM399450 500 B cells, proB.FrBC.BM, CD19+ IgM- CD43+ AA4.1+ CD45R+, Bone marrow, avg-2 Immgen.org, GSE15907 3.001E-5 4.678E-3 3.866E-2
6.549E-2
 9 402
15 GSM538350 500 B cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate CD45R- AA4.1+ CD, Fetal Liver, avg-1 Immgen.org, GSE15907 4.066E-5 5.627E-3 4.651E-2
8.873E-2
 9 418
16 gudmap developingGonad e12.5 testes k1 1000 DevelopingGonad e12.5 testes emap-29069 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.126E-5 5.627E-3 4.651E-2
9.003E-2
 10 524
17 gudmap developingGonad e14.5 testes 1000 k5 DevelopingGonad e14.5 testes emap-6710 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.971E-5 6.381E-3
5.274E-2
1.085E-1
 9 429
18 GSM777027 500 B cells, B.Pl.AA4+220-.BM, CD138+ AA4.1+ CD43- CD45R-, Bone marrow, avg-3 Immgen.org, GSE15907 5.898E-5 7.150E-3
5.910E-2
1.287E-1
 8 339
19 gudmap developingGonad e14.5 testes 1000 DevelopingGonad e14.5 testes emap-6710 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 9.096E-5 1.045E-2
8.634E-2
1.985E-1
 12 822
20 fetal replicating Top 500 Cluster 0 fetal replicating Top 500 Cluster 0 Brain Map - Barres 1.059E-4 1.155E-2
9.550E-2
2.311E-1
 5 118
21 gudmap developingGonad e11.5 testes k5 1000 DevelopingGonad e11.5 testes emap-3226 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.545E-4 1.605E-2
1.327E-1
3.371E-1
 9 498
22 GSM538340 500 B cells, preB.FrD.FL, AA4.1+ IgM- CD19+ CD43- CD24+, Fetal Liver, avg-3 Immgen.org, GSE15907 1.697E-4 1.652E-2
1.366E-1
3.703E-1
 8 395
23 GSM538345 500 B cells, proB.CLP.BM, CD19- IgM- CD43+ CD24intermediate CD45R- AA4.1+ CD, Bone marrow, avg-2 Immgen.org, GSE15907 1.817E-4 1.652E-2
1.366E-1
3.966E-1
 8 399
24 GSM399397 500 alpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3 Immgen.org, GSE15907 1.817E-4 1.652E-2
1.366E-1
3.966E-1
 8 399
25 GSM538354 500 B cells, proB.FrA.BM, AA4.1+ CD117+ IL7R+ CD45R+ CD24- CD19- IgM-, Bone marrow, avg-1 Immgen.org, GSE15907 2.031E-4 1.773E-2
1.465E-1
4.432E-1
 7 304
26 GSM791149 500 alpha beta T cells, preT.DN3B.Th, Lin-/lo CD25hi CD44- CD28+, Thymus, avg-3 Immgen.org, GSE15907 2.296E-4 1.862E-2
1.539E-1
5.010E-1
 8 413
27 gudmap kidney single cell e11.5 MetanephMesench Scamp 1000 kidney single cell e11.5 MetanephMesench StemCellamp top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.304E-4 1.862E-2
1.539E-1
5.027E-1
 10 646
28 gudmap developingGonad P2 epididymis 1000 k5 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.437E-4 1.891E-2
1.563E-1
5.319E-1
 5 141
29 gudmap developingGonad e11.5 testes and mesonephros k5 1000 DevelopingGonad e11.5 testes and mesonephros emap-3226 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.558E-4 1.891E-2
1.563E-1
5.582E-1
 9 533
30 GSM476658 500 gamma delta T cells, Tgd.vg2-24ahi.Th, TCRd+ Vg2- CD24+, Thymus, avg-2 Immgen.org, GSE15907 2.655E-4 1.891E-2
1.563E-1
5.794E-1
 8 422
31 gudmap developingGonad e11.5 testes k3 500 DevelopingGonad e11.5 testes emap-3226 k-means-cluster#3 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.687E-4 1.891E-2
1.563E-1
5.863E-1
 5 144
32 PCBC ratio EB from-OSK-L-l-p53KD vs EB from-ESC cfr-2X-p05 Embryoid Body Cells-reprogram OSK-L-l-p53KD vs Embryoid Body Cells-reprogram NA-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 3.458E-4 2.316E-2
1.915E-1
7.545E-1
 4 84
33 gudmap developingGonad P2 testes 1000 DevelopingGonad P2 testes emap-30171 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.738E-4 2.316E-2
1.915E-1
8.156E-1
 11 819
34 GSM777024 500 B cells, B.Pl.AA4+220+.BM, CD138+ AA4.1+ CD43- CD45R+, Bone marrow, avg-3 Immgen.org, GSE15907 3.791E-4 2.316E-2
1.915E-1
8.272E-1
 7 337
35 Lungmap Mouse e14.5 Epithelial (GSE52583) Top 500 All Mouse Lung E14.5 Epithelial top 500 Lungmap Mouse Single Cell (Lungmap.net) 3.843E-4 2.316E-2
1.915E-1
8.386E-1
 8 446
36 gudmap developingGonad e12.5 testes k4 500 DevelopingGonad e12.5 testes emap-29069 k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.902E-4 2.316E-2
1.915E-1
8.513E-1
 6 241
37 gudmap kidney single cell e11.5 MetanephMesench Scamp 500 kidney single cell e11.5 MetanephMesench StemCellamp top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.928E-4 2.316E-2
1.915E-1
8.570E-1
 7 339
38 GSM399452 100 B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3 Immgen.org, GSE15907 4.129E-4 2.371E-2
1.960E-1
9.010E-1
 4 88
39 GSM538352 100 B cells, proB.FrA.BM, CD19- IgM- CD43+ CD24intermediate CD45R+ AA4.1+ CD, Bone marrow, avg-2 Immgen.org, GSE15907 4.311E-4 2.412E-2
1.993E-1
9.406E-1
 4 89
40 gudmap developingGonad P2 testes 1000 k2 DevelopingGonad P2 testes emap-30171 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.673E-4 2.444E-2
2.020E-1
1.000E0
 7 349
41 GSM476675 500 gamma delta T cells, Tgd.Th, TCRd+ CD3e+, Thymus, avg-3 Immgen.org, GSE15907 4.673E-4 2.444E-2
2.020E-1
1.000E0
 7 349
42 gudmap developingGonad e11.5 testes and mesonephros k4 1000 DevelopingGonad e11.5 testes and mesonephros emap-3226 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.883E-4 2.444E-2
2.020E-1
1.000E0
 5 164
43 gudmap dev gonad e11.5 F PrimGermCell Oct k3 1000 dev gonad e11.5 F PrimGermCell Oct k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 4.923E-4 2.444E-2
2.020E-1
1.000E0
 8 463
44 gudmap developingGonad e11.5 testes k1 200 DevelopingGonad e11.5 testes emap-3226 k-means-cluster#1 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 4.927E-4 2.444E-2
2.020E-1
1.000E0
 3 39
45 gudmap developingGonad e12.5 epididymis k1 1000 DevelopingGonad e12.5 epididymis emap-29139 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.942E-4 2.881E-2
2.381E-1
1.000E0
 6 261
46 GSM538309 500 NK cells, NK.MCMV1.Sp, CD3-,NK1.1+, Spleen, avg-3 Immgen.org, GSE15907 6.296E-4 2.986E-2
2.468E-1
1.000E0
 7 367
47 GSM538204 500 B cells, B.FrE.FL, AA4.1+ IgM+ CD19+ CD43- CD24+, Fetal Liver, avg-3 Immgen.org, GSE15907 6.818E-4 3.165E-2
2.616E-1
1.000E0
 7 372
48 GSM399438 500 B cells, B.FrE.BM, CD19+ IgM+ AA4.1+ HSA+, Bone marrow, avg-3 Immgen.org, GSE15907 7.260E-4 3.233E-2
2.672E-1
1.000E0
 7 376
49 GSM791154 500 alpha beta T cells, T.DN4.Th, Lin-/lo CD25- CD44- CD28+, Thymus, avg-3 Immgen.org, GSE15907 7.260E-4 3.233E-2
2.672E-1
1.000E0
 7 376
50 gudmap developingGonad e18.5 testes 200 k3 DevelopingGonad e18.5 testes emap-11164 k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 7.521E-4 3.282E-2
2.713E-1
1.000E0
 3 45
Show 45 more annotations

15: Computational [Display Chart] 375 annotations before applied cutoff / 9399 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GNF2 SMC4L1 Neighborhood of SMC4L1 MSigDb: C4 - CGN: Cancer Gene Neighborhood 2.432E-4 4.842E-2
3.150E-1
9.119E-2
 5 76
2 MORF ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood 3.406E-4 4.842E-2
3.150E-1
1.277E-1
 7 178
3 module 123 Genes in module 123 MSigDb: C4 - CM: Cancer Modules 3.873E-4 4.842E-2
3.150E-1
1.453E-1
 8 240

16: MicroRNA [Display Chart] 1881 annotations before applied cutoff / 19844 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 TTTGTAG,MIR-520D:MSigDB TTTGTAG,MIR-520D:MSigDB MSigDB 5.888E-6 1.108E-2
8.990E-2
 1.108E-2 9 310
2 hsa-miR-1283:PITA hsa-miR-1283:PITA TOP PITA 1.323E-5 1.245E-2
1.010E-1
 2.489E-2 12 638
3 hsa-miR-377:PITA hsa-miR-377:PITA TOP PITA 2.139E-5 1.341E-2
1.088E-1
 4.023E-2 10 459
4 hsa-miR-603:PITA hsa-miR-603:PITA TOP PITA 3.289E-5 1.390E-2
1.128E-1
6.186E-2
 9 385
5 miR-222:PicTar miR-222:PicTar PicTar 3.695E-5 1.390E-2
1.128E-1
6.949E-2
 7 219
6 miR-221:PicTar miR-221:PicTar PicTar 4.640E-5 1.455E-2
1.181E-1
8.727E-2
 7 227
7 hsa-miR-885-5p:mirSVR highEffct hsa-miR-885-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.683E-5 1.578E-2
1.281E-1
1.257E-1
 11 636
8 hsa-miR-885-5p:PITA hsa-miR-885-5p:PITA TOP PITA 6.711E-5 1.578E-2
1.281E-1
1.262E-1
 6 165
9 hsa-miR-298:PITA hsa-miR-298:PITA TOP PITA 1.343E-4 2.613E-2
2.121E-1
2.525E-1
 7 269
10 hsa-miR-9:miRecords TarBase hsa-miR-9:miRecords TarBase miRecords_TarBase 1.714E-4 2.613E-2
2.121E-1
3.225E-1
 2 5
11 hsa-miR-129-5p:PITA hsa-miR-129-5p:PITA TOP PITA 1.972E-4 2.613E-2
2.121E-1
3.709E-1
 9 487
12 hsa-miR-9:miRTarbase hsa-miR-9:miRTarbase miRTarbase 2.143E-4 2.613E-2
2.121E-1
4.032E-1
 3 28
13 hsa-miR-133b:TargetScan hsa-miR-133b:TargetScan TargetScan 2.468E-4 2.613E-2
2.121E-1
4.643E-1
 9 502
14 hsa-miR-133a:TargetScan hsa-miR-133a:TargetScan TargetScan 2.468E-4 2.613E-2
2.121E-1
4.643E-1
 9 502
15 miR-129:PicTar miR-129:PicTar PicTar 2.571E-4 2.613E-2
2.121E-1
4.837E-1
 6 211
16 hsa-miR-557:PITA hsa-miR-557:PITA TOP PITA 2.837E-4 2.613E-2
2.121E-1
5.337E-1
 7 304
17 hsa-miR-507:PITA hsa-miR-507:PITA TOP PITA 2.837E-4 2.613E-2
2.121E-1
5.337E-1
 7 304
18 CTTTGTA,MIR-524:MSigDB CTTTGTA,MIR-524:MSigDB MSigDB 3.113E-4 2.613E-2
2.121E-1
5.856E-1
 8 409
19 hsa-miR-574-3p:PITA hsa-miR-574-3p:PITA TOP PITA 3.206E-4 2.613E-2
2.121E-1
6.031E-1
 3 32
20 hsa-miR-181b:TargetScan hsa-miR-181b:TargetScan TargetScan 3.267E-4 2.613E-2
2.121E-1
6.145E-1
 12 893
21 hsa-miR-181a:TargetScan hsa-miR-181a:TargetScan TargetScan 3.267E-4 2.613E-2
2.121E-1
6.145E-1
 12 893
22 hsa-miR-181d:TargetScan hsa-miR-181d:TargetScan TargetScan 3.267E-4 2.613E-2
2.121E-1
6.145E-1
 12 893
23 hsa-miR-181c:TargetScan hsa-miR-181c:TargetScan TargetScan 3.267E-4 2.613E-2
2.121E-1
6.145E-1
 12 893
24 hsa-miR-548p:PITA hsa-miR-548p:PITA TOP PITA 3.334E-4 2.613E-2
2.121E-1
6.271E-1
 12 895
25 hsa-miR-196a*:mirSVR highEffct hsa-miR-196a*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.798E-4 2.857E-2
2.319E-1
7.143E-1
 12 908
26 miR-23b:PicTar miR-23b:PicTar PicTar 3.959E-4 2.864E-2
2.325E-1
7.446E-1
 8 424
27 hsa-miR-2114*:mirSVR highEffct hsa-miR-2114*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.279E-4 2.981E-2
2.420E-1
8.048E-1
 8 429
28 hsa-miR-200c:PITA hsa-miR-200c:PITA TOP PITA 5.696E-4 3.406E-2
2.764E-1
1.000E0
 11 815
29 hsa-miR-200b:PITA hsa-miR-200b:PITA TOP PITA 5.696E-4 3.406E-2
2.764E-1
1.000E0
 11 815
30 hsa-miR-429:PITA hsa-miR-429:PITA TOP PITA 5.873E-4 3.406E-2
2.764E-1
1.000E0
 11 818
31 hsa-let-7f:miRTarbase hsa-let-7f:miRTarbase miRTarbase 6.105E-4 3.406E-2
2.764E-1
1.000E0
 2 9
32 CATGTAA,MIR-496:MSigDB CATGTAA,MIR-496:MSigDB MSigDB 6.264E-4 3.406E-2
2.764E-1
1.000E0
 5 164
33 hsa-miR-129-5p:TargetScan hsa-miR-129-5p:TargetScan TargetScan 6.365E-4 3.406E-2
2.764E-1
1.000E0
 7 348
34 miR-200b:PicTar miR-200b:PicTar PicTar 7.363E-4 3.406E-2
2.764E-1
1.000E0
 8 466
35 miR-200c:PicTar miR-200c:PicTar PicTar 7.466E-4 3.406E-2
2.764E-1
1.000E0
 8 467
36 hsa-miR-548b-5p:PITA hsa-miR-548b-5p:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
37 hsa-miR-548c-5p:PITA hsa-miR-548c-5p:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
38 hsa-miR-548j:PITA hsa-miR-548j:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
39 hsa-miR-548i:PITA hsa-miR-548i:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
40 hsa-miR-548d-5p:PITA hsa-miR-548d-5p:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
41 hsa-miR-548h:PITA hsa-miR-548h:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
42 hsa-miR-548a-5p:PITA hsa-miR-548a-5p:PITA TOP PITA 7.604E-4 3.406E-2
2.764E-1
1.000E0
 11 844
43 GCAAAAA,MIR-129:MSigDB GCAAAAA,MIR-129:MSigDB MSigDB 8.181E-4 3.579E-2
2.905E-1
1.000E0
 5 174
44 hsa-miR-873:TargetScan hsa-miR-873:TargetScan TargetScan 8.612E-4 3.682E-2
2.988E-1
1.000E0
 5 176
45 hsa-miR-150:miRTarbase hsa-miR-150:miRTarbase miRTarbase 9.276E-4 3.878E-2
3.147E-1
1.000E0
 2 11
46 TGTGTGA,MIR-377:MSigDB TGTGTGA,MIR-377:MSigDB MSigDB 1.051E-3 4.296E-2
3.487E-1
1.000E0
 5 184
47 ACTGAAA,MIR-30A-3P:MSigDB ACTGAAA,MIR-30A-3P:MSigDB MSigDB 1.184E-3 4.638E-2
3.765E-1
1.000E0
 5 189
48 ACTGAAA,MIR-30E-3P:MSigDB ACTGAAA,MIR-30E-3P:MSigDB MSigDB 1.184E-3 4.638E-2
3.765E-1
1.000E0
 5 189
Show 43 more annotations

17: Drug [Display Chart] 18422 annotations before applied cutoff / 22098 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C027576 4-hydroxy-2-nonenal CTD 7.653E-12 1.410E-7 1.466E-6 1.410E-7 20 783
2 CID000107707 Zlllal Stitch 9.359E-10 7.244E-6 7.533E-5 1.724E-5 16 613
3 D000068877 Imatinib Mesylate CTD 1.180E-9 7.244E-6 7.533E-5 2.173E-5 9 127
4 CID000005562 A25618 Stitch 3.744E-9 1.724E-5 1.793E-4 6.898E-5 17 777
5 C113580 U 0126 CTD 5.737E-8 1.852E-4 1.925E-3 1.057E-3 12 422
6 CID000003154 Cosopt Stitch 6.031E-8 1.852E-4 1.925E-3 1.111E-3 11 341
7 CID000105082 AC1L2Y08 Stitch 7.401E-8 1.948E-4 2.025E-3 1.363E-3 12 432
8 C016392 3,3'-diindolylmethane CTD 1.472E-7 3.389E-4 3.524E-3 2.712E-3 7 106
9 CID000014888 arsenic trioxide Stitch 1.757E-7 3.389E-4 3.524E-3 3.236E-3 12 468
10 C097613 imatinib CTD 2.149E-7 3.389E-4 3.524E-3 3.959E-3 7 112
11 D005944 Glucosamine CTD 2.230E-7 3.389E-4 3.524E-3 4.109E-3 10 306
12 C093973 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one CTD 2.267E-7 3.389E-4 3.524E-3 4.177E-3 11 389
13 CID000435143 NSC-364372 Stitch 2.518E-7 3.389E-4 3.524E-3 4.639E-3 12 484
14 CID004629339 AC1NDP1U Stitch 2.576E-7 3.389E-4 3.524E-3 4.745E-3 7 115
15 D003474 Curcumin CTD 2.762E-7 3.392E-4 3.527E-3 5.088E-3 15 804
16 D010894 Piroxicam CTD 3.619E-7 3.866E-4 4.020E-3 6.666E-3 13 601
17 C074702 chromium hexavalent ion CTD 3.768E-7 3.866E-4 4.020E-3 6.941E-3 9 247
18 CID000005056 trans-3,4,5-trihydroxystilbene Stitch 4.126E-7 3.866E-4 4.020E-3 7.600E-3 13 608
19 CID000446904 homobiotin Stitch 4.142E-7 3.866E-4 4.020E-3 7.630E-3 6 76
20 C093642 SB 203580 CTD 4.340E-7 3.866E-4 4.020E-3 7.995E-3 10 329
21 D003676 Deferoxamine CTD 4.407E-7 3.866E-4 4.020E-3 8.119E-3 8 183
22 622 DN resveratrol; Down 200; 50uM; MCF7; HG-U133A Broad Institute CMAP 5.860E-7 4.884E-4 5.079E-3 1.080E-2 8 190
23 7339 UP Tracazolate hydrochloride [41094-88-6]; Up 200; 11.8uM; MCF7; HT HG-U133A Broad Institute CMAP 6.098E-7 4.884E-4 5.079E-3 1.123E-2 8 191
24 C005961 bis(tri-n-butyltin)oxide CTD 7.003E-7 5.129E-4 5.334E-3 1.290E-2 12 533
25 CID000000544 arsenite Stitch 7.052E-7 5.129E-4 5.334E-3 1.299E-2 10 347
26 D013196 Dihydrotestosterone CTD 7.239E-7 5.129E-4 5.334E-3 1.334E-2 10 348
27 C400082 bortezomib CTD 1.038E-6 7.084E-4 7.366E-3 1.913E-2 15 893
28 D004008 Diclofenac CTD 1.091E-6 7.175E-4 7.461E-3 2.009E-2 12 556
29 MESH:D003924/D007501-M Diabetes Mellitus, Type 2 affected by Iron CTD Marker 1.769E-6 1.124E-3 1.169E-2 3.259E-2 3 7
30 D008767 Methylmercury Compounds CTD 2.053E-6 1.261E-3 1.311E-2 3.782E-2 13 702
31 CID000001444 AC1L1BHQ Stitch 2.458E-6 1.461E-3 1.519E-2 4.529E-2 8 230
32 C019536 potassium bromate CTD 2.644E-6 1.512E-3 1.572E-2 4.871E-2 6 104
33 CID000644213 GW9662 Stitch 2.708E-6 1.512E-3 1.572E-2 4.989E-2 7 163
34 D019345 Zinc Acetate CTD 2.820E-6 1.528E-3 1.589E-2
5.196E-2
 7 164
35 D017382 Reactive Oxygen Species CTD 3.053E-6 1.597E-3 1.661E-2
5.625E-2
 9 318
36 CID000006497 dimethyl sulfate Stitch 3.121E-6 1.597E-3 1.661E-2
5.750E-2
 6 107
37 CID000003310 E-PEG Stitch 3.423E-6 1.669E-3 1.735E-2
6.306E-2
 12 621
38 4471 UP Astemizole [68844-77-9]; Up 200; 8.8uM; PC3; HT HG-U133A Broad Institute CMAP 3.442E-6 1.669E-3 1.735E-2
6.340E-2
 7 169
39 4617 UP Thonzonium bromide [553-08-2]; Up 200; 6.8uM; PC3; HT HG-U133A Broad Institute CMAP 4.017E-6 1.834E-3 1.907E-2
7.401E-2
 7 173
40 CID000448381 2hqu Stitch 4.167E-6 1.834E-3 1.907E-2
7.676E-2
 8 247
41 5745 DN Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP 4.173E-6 1.834E-3 1.907E-2
7.688E-2
 7 174
42 C097240 15-deoxy-delta(12,14)-prostaglandin J2 CTD 4.286E-6 1.834E-3 1.907E-2
7.895E-2
 6 113
43 C060836 pioglitazone CTD 4.500E-6 1.834E-3 1.907E-2
8.290E-2
 7 176
44 D002083 Butylated Hydroxyanisole CTD 4.511E-6 1.834E-3 1.907E-2
8.309E-2
 6 114
45 D012402 Rotenone CTD 4.548E-6 1.834E-3 1.907E-2
8.378E-2
 14 878
46 C034613 triacsin C CTD 4.580E-6 1.834E-3 1.907E-2
8.437E-2
 5 65
47 7094 UP lomustine; Up 200; 100uM; PC3; HT HG-U133A Broad Institute CMAP 4.848E-6 1.900E-3 1.976E-2
8.931E-2
 7 178
48 C072553 benzyloxycarbonylleucyl-leucyl-leucine aldehyde CTD 5.330E-6 2.046E-3 2.127E-2
9.818E-2
 11 538
49 C030973 cupric oxide CTD 5.520E-6 2.075E-3 2.158E-2
1.017E-1
 11 540
50 CID000176155 SB203580 Stitch 5.784E-6 2.131E-3 2.216E-2
1.066E-1
 13 772
Show 45 more annotations

18: Disease [Display Chart] 1635 annotations before applied cutoff / 16150 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 umls:C0079731 B-Cell Lymphomas DisGeNET Curated 3.142E-8 2.924E-5 2.332E-4 5.138E-5 16 576
2 umls:C0079744 Diffuse Large B-Cell Lymphoma DisGeNET Curated 3.737E-8 2.924E-5 2.332E-4 6.109E-5 15 505
3 umls:C0006413 Burkitt Lymphoma DisGeNET Curated 5.639E-8 2.924E-5 2.332E-4 9.220E-5 10 194
4 umls:C0027708 Nephroblastoma DisGeNET Curated 8.486E-8 2.924E-5 2.332E-4 1.387E-4 12 321
5 umls:C0024301 Lymphoma, Follicular DisGeNET Curated 1.073E-7 2.924E-5 2.332E-4 1.754E-4 12 328
6 umls:C0019829 Hodgkin Disease DisGeNET Curated 1.073E-7 2.924E-5 2.332E-4 1.754E-4 12 328
7 umls:C0008626 Congenital chromosomal disease DisGeNET Curated 4.784E-7 1.117E-4 8.913E-4 7.821E-4 14 531
8 umls:C0023493 Adult T-Cell Lymphoma/Leukemia DisGeNET Curated 6.049E-7 1.168E-4 9.318E-4 9.891E-4 13 461
9 umls:C0334634 Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse DisGeNET Curated 6.430E-7 1.168E-4 9.318E-4 1.051E-3 11 317
10 umls:C0598766 Leukemogenesis DisGeNET BeFree 1.162E-6 1.900E-4 1.515E-3 1.900E-3 15 660
11 umls:C0016667 Fragile X Syndrome DisGeNET Curated 1.344E-6 1.998E-4 1.594E-3 2.198E-3 7 108
12 umls:C0009447 Common Variable Immunodeficiency DisGeNET Curated 2.885E-6 3.931E-4 3.135E-3 4.717E-3 7 121
13 umls:C0023470 Myeloid Leukemia DisGeNET Curated 3.659E-6 4.413E-4 3.520E-3 5.983E-3 12 458
14 umls:C1333064 Classical Hodgkin's Lymphoma DisGeNET BeFree 3.779E-6 4.413E-4 3.520E-3 6.179E-3 7 126
15 umls:C0035335 Retinoblastoma DisGeNET Curated 4.090E-6 4.458E-4 3.556E-3 6.687E-3 12 463
16 umls:C0009319 Colitis DisGeNET Curated 1.027E-5 1.018E-3 8.118E-3 1.679E-2 12 507
17 umls:C0023473 Myeloid Leukemia, Chronic DisGeNET Curated 1.058E-5 1.018E-3 8.118E-3 1.730E-2 15 791
18 umls:C0025149 Medulloblastoma DisGeNET Curated 1.201E-5 1.091E-3 8.703E-3 1.964E-2 12 515
19 umls:C1961102 Precursor Cell Lymphoblastic Leukemia Lymphoma DisGeNET Curated 2.004E-5 1.724E-3 1.375E-2 3.276E-2 14 733
20 umls:C0023890 Liver Cirrhosis DisGeNET Curated 2.659E-5 2.174E-3 1.734E-2 4.348E-2 12 558
21 umls:C1292753 Primary Effusion Lymphoma DisGeNET BeFree 3.196E-5 2.488E-3 1.985E-2
5.225E-2
 6 118
22 umls:C0007847 Malignant tumor of cervix DisGeNET BeFree 4.148E-5 3.055E-3 2.437E-2
6.782E-2
 15 889
23 umls:C0023440 Acute Erythroblastic Leukemia DisGeNET Curated 4.297E-5 3.055E-3 2.437E-2
7.026E-2
 7 183
24 umls:C0023492 Leukemia, T-Cell DisGeNET Curated 5.322E-5 3.626E-3 2.892E-2
8.702E-2
 9 334
25 umls:C1261473 Sarcoma DisGeNET Curated 9.234E-5 5.908E-3 4.712E-2
1.510E-1
 13 737
26 umls:C0024419 Waldenstrom Macroglobulinemia DisGeNET Curated 9.394E-5 5.908E-3 4.712E-2
1.536E-1
 5 89
27 umls:C1520166 Xenograft Model DisGeNET BeFree 1.151E-4 6.971E-3
5.561E-2
1.882E-1
 11 551
28 umls:C0023485 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma DisGeNET Curated 1.280E-4 7.475E-3
5.963E-2
2.093E-1
 5 95
29 umls:C0349636 Pre B-cell acute lymphoblastic leukemia DisGeNET BeFree 1.401E-4 7.512E-3
5.992E-2
2.290E-1
 3 20
30 umls:C0038220 Status Epilepticus DisGeNET Curated 1.413E-4 7.512E-3
5.992E-2
2.309E-1
 5 97
31 umls:C0280100 Solid tumour DisGeNET BeFree 1.468E-4 7.512E-3
5.992E-2
2.400E-1
 13 772
32 umls:C0024121 Lung Neoplasms DisGeNET Curated 1.487E-4 7.512E-3
5.992E-2
2.431E-1
 13 773
33 umls:C1292769 Precursor B-cell lymphoblastic leukemia DisGeNET BeFree 1.540E-4 7.512E-3
5.992E-2
2.518E-1
 9 384
34 umls:C0026499 Monosomy DisGeNET BeFree 1.562E-4 7.512E-3
5.992E-2
2.554E-1
 6 157
35 umls:C0023449 Acute lymphocytic leukemia DisGeNET Curated 2.382E-4 1.112E-2
8.867E-2
3.895E-1
 13 811
36 umls:C0376628 Chromosome Breakage DisGeNET Curated 2.584E-4 1.112E-2
8.867E-2
4.224E-1
 2 5
37 umls:C1455780 Aortic valve sclerosis DisGeNET BeFree 2.584E-4 1.112E-2
8.867E-2
4.224E-1
 2 5
38 umls:C0428796 Senile sclerosis of aortic cusp DisGeNET BeFree 2.584E-4 1.112E-2
8.867E-2
4.224E-1
 2 5
39 umls:C0476089 Endometrial Carcinoma DisGeNET Curated 2.792E-4 1.170E-2
9.337E-2
4.565E-1
 12 715
40 umls:C0206180 Ki-1+ Anaplastic Large Cell Lymphoma DisGeNET Curated 3.063E-4 1.246E-2
9.940E-2
5.007E-1
 7 251
41 umls:C0079746 Immunoblastic Large-Cell Lymphoma DisGeNET BeFree 3.125E-4 1.246E-2
9.940E-2
5.109E-1
 3 26
42 umls:C0022578 Keratoconus DisGeNET Curated 3.668E-4 1.406E-2
1.121E-1
5.998E-1
 4 66
43 umls:C0079772 T-Cell Lymphoma DisGeNET Curated 3.701E-4 1.406E-2
1.121E-1
6.051E-1
 7 259
44 umls:C1266082 Atypical medullary carcinoma DisGeNET BeFree 3.862E-4 1.406E-2
1.121E-1
6.315E-1
 2 6
45 umls:C0000768 Congenital Abnormality DisGeNET Curated 3.869E-4 1.406E-2
1.121E-1
6.326E-1
 11 634
46 umls:C0042769 Virus Diseases DisGeNET Curated 4.303E-4 1.530E-2
1.220E-1
7.036E-1
 12 750
47 umls:C1961099 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma DisGeNET Curated 5.004E-4 1.741E-2
1.389E-1
8.181E-1
 8 358
48 umls:C0016689 Freckles DisGeNET Curated 5.389E-4 1.817E-2
1.450E-1
8.811E-1
 2 7
49 umls:C3539878 Triple Negative Breast Neoplasms DisGeNET BeFree 5.446E-4 1.817E-2
1.450E-1
8.905E-1
 9 456
50 umls:C0007193 Cardiomyopathy, Dilated DisGeNET Curated 5.788E-4 1.893E-2
1.510E-1
9.463E-1
 8 366
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