Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc110_8, positive side

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1: GO: Molecular Function [Display Chart] 8 input genes in category / 19 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0030246 carbohydrate binding 3.575E-10 6.792E-9 2.410E-8 6.792E-9 6 289
2 GO:0001530 lipopolysaccharide binding 4.050E-5 3.848E-4 1.365E-3 7.696E-4 2 23
3 GO:0042497 triacyl lipopeptide binding 8.572E-4 4.072E-3 1.445E-2 1.629E-2 1 2
4 GO:0042498 diacyl lipopeptide binding 8.572E-4 4.072E-3 1.445E-2 1.629E-2 1 2
5 GO:0001875 lipopolysaccharide receptor activity 2.142E-3 6.783E-3 2.406E-2 4.070E-2 1 5
6 GO:0070891 lipoteichoic acid binding 2.142E-3 6.783E-3 2.406E-2 4.070E-2 1 5
7 GO:0071723 lipopeptide binding 3.425E-3 9.150E-3 3.246E-2
6.508E-2
 1 8
8 GO:0035325 Toll-like receptor binding 3.853E-3 9.150E-3 3.246E-2
7.320E-2
 1 9
9 GO:0042834 peptidoglycan binding 5.134E-3 1.084E-2 3.845E-2
9.754E-2
 1 12
10 GO:0038187 pattern recognition receptor activity 7.266E-3 1.255E-2 4.453E-2
1.381E-1
 1 17
11 GO:0008329 signaling pattern recognition receptor activity 7.266E-3 1.255E-2 4.453E-2
1.381E-1
 1 17
12 GO:0045309 protein phosphorylated amino acid binding 1.194E-2 1.891E-2
6.709E-2
2.269E-1
 1 28
13 GO:0051219 phosphoprotein binding 3.296E-2 4.586E-2
1.627E-1
6.262E-1
 1 78
14 GO:0048029 monosaccharide binding 3.379E-2 4.586E-2
1.627E-1
6.421E-1
 1 80
Show 9 more annotations

2: GO: Biological Process [Display Chart] 8 input genes in category / 377 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0050766 positive regulation of phagocytosis 1.672E-6 5.071E-4 3.301E-3 6.305E-4 3 59
2 GO:0007585 respiratory gaseous exchange 2.690E-6 5.071E-4 3.301E-3 1.014E-3 3 69
3 GO:0050764 regulation of phagocytosis 5.236E-6 6.580E-4 4.284E-3 1.974E-3 3 86
4 GO:0045807 positive regulation of endocytosis 1.987E-5 1.873E-3 1.219E-2 7.490E-3 3 134
5 GO:0030100 regulation of endocytosis 9.442E-5 7.119E-3 4.635E-2 3.560E-2 3 226
6 GO:0006909 phagocytosis 1.350E-4 8.485E-3
5.525E-2
5.091E-2
 3 255
7 GO:0052558 induction by organism of immune response of other organism involved in symbiotic interaction 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
8 GO:0052345 positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
9 GO:0052347 positive regulation by symbiont of defense-related host nitric oxide production 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
10 GO:0052555 positive regulation by organism of immune response of other organism involved in symbiotic interaction 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
11 GO:0052559 induction by symbiont of host immune response 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
12 GO:0052063 induction by symbiont of defense-related host nitric oxide production 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
13 GO:0052556 positive regulation by symbiont of host immune response 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
14 GO:0052263 induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
15 GO:0052163 modulation by symbiont of defense-related host nitric oxide production 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
16 GO:0052302 modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
17 GO:0042892 chloramphenicol transport 4.296E-4 9.526E-3
6.202E-2
1.620E-1
 1 1
18 GO:0050900 leukocyte migration 4.579E-4 9.591E-3
6.245E-2
1.726E-1
 3 386
19 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction 8.590E-4 1.214E-2
7.905E-2
3.238E-1
 1 2
20 GO:0042495 detection of triacyl bacterial lipopeptide 8.590E-4 1.214E-2
7.905E-2
3.238E-1
 1 2
21 GO:0042496 detection of diacyl bacterial lipopeptide 8.590E-4 1.214E-2
7.905E-2
3.238E-1
 1 2
22 GO:0052565 response to defense-related host nitric oxide production 8.590E-4 1.214E-2
7.905E-2
3.238E-1
 1 2
23 GO:0050828 regulation of liquid surface tension 8.590E-4 1.214E-2
7.905E-2
3.238E-1
 1 2
24 GO:0042035 regulation of cytokine biosynthetic process 9.120E-4 1.214E-2
7.905E-2
3.438E-1
 2 108
25 GO:0042089 cytokine biosynthetic process 1.124E-3 1.214E-2
7.905E-2
4.238E-1
 2 120
26 GO:0042107 cytokine metabolic process 1.162E-3 1.214E-2
7.905E-2
4.379E-1
 2 122
27 GO:0071727 cellular response to triacyl bacterial lipopeptide 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
28 GO:0052552 modulation by organism of immune response of other organism involved in symbiotic interaction 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
29 GO:0032289 central nervous system myelin formation 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
30 GO:0052251 induction by organism of defense response of other organism involved in symbiotic interaction 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
31 GO:0052553 modulation by symbiont of host immune response 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
32 GO:0002752 cell surface pattern recognition receptor signaling pathway 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
33 GO:0052255 modulation by organism of defense response of other organism involved in symbiotic interaction 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
34 GO:0038123 toll-like receptor TLR1:TLR2 signaling pathway 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
35 GO:0052510 positive regulation by organism of defense response of other organism involved in symbiotic interaction 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
36 GO:0070340 detection of bacterial lipopeptide 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
37 GO:0032741 positive regulation of interleukin-18 production 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
38 GO:0071725 response to triacyl bacterial lipopeptide 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
39 GO:0052031 modulation by symbiont of host defense response 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
40 GO:0052509 positive regulation by symbiont of host defense response 1.288E-3 1.214E-2
7.905E-2
4.857E-1
 1 3
41 GO:0071224 cellular response to peptidoglycan 1.717E-3 1.439E-2
9.367E-2
6.474E-1
 1 4
42 GO:0045085 negative regulation of interleukin-2 biosynthetic process 1.717E-3 1.439E-2
9.367E-2
6.474E-1
 1 4
43 GO:0042494 detection of bacterial lipoprotein 1.717E-3 1.439E-2
9.367E-2
6.474E-1
 1 4
44 GO:0042891 antibiotic transport 1.717E-3 1.439E-2
9.367E-2
6.474E-1
 1 4
45 GO:0038124 toll-like receptor TLR6:TLR2 signaling pathway 1.717E-3 1.439E-2
9.367E-2
6.474E-1
 1 4
46 GO:0071724 response to diacyl bacterial lipopeptide 2.146E-3 1.722E-2
1.121E-1
8.091E-1
 1 5
47 GO:0071726 cellular response to diacyl bacterial lipopeptide 2.146E-3 1.722E-2
1.121E-1
8.091E-1
 1 5
48 GO:0071221 cellular response to bacterial lipopeptide 2.575E-3 1.797E-2
1.170E-1
9.708E-1
 1 6
49 GO:0070339 response to bacterial lipopeptide 2.575E-3 1.797E-2
1.170E-1
9.708E-1
 1 6
50 GO:0052564 response to immune response of other organism involved in symbiotic interaction 2.575E-3 1.797E-2
1.170E-1
9.708E-1
 1 6
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 8 input genes in category / 21 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0042599 lamellar body 5.513E-8 1.158E-6 4.221E-6 1.158E-6 3 20
2 GO:0045334 clathrin-coated endocytic vesicle 2.401E-6 1.713E-5 6.244E-5 5.042E-5 3 68
3 GO:0030139 endocytic vesicle 2.447E-6 1.713E-5 6.244E-5 5.139E-5 4 265
4 GO:0005581 collagen trimer 5.237E-6 2.749E-5 1.002E-4 1.100E-4 3 88
5 GO:0030136 clathrin-coated vesicle 3.271E-5 1.374E-4 5.008E-4 6.869E-4 3 162
6 GO:0030135 coated vesicle 1.067E-4 3.733E-4 1.361E-3 2.240E-3 3 241
7 GO:0005771 multivesicular body 1.581E-4 4.742E-4 1.729E-3 3.319E-3 2 46
8 GO:0030141 secretory granule 4.749E-4 1.247E-3 4.544E-3 9.973E-3 3 400
9 GO:0005791 rough endoplasmic reticulum 6.332E-4 1.353E-3 4.932E-3 1.330E-2 2 92
10 GO:0031012 extracellular matrix 6.443E-4 1.353E-3 4.932E-3 1.353E-2 3 444
11 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex 8.393E-4 1.602E-3 5.841E-3 1.762E-2 1 2
12 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex 1.259E-3 2.203E-3 8.029E-3 2.643E-2 1 3
13 GO:0005770 late endosome 3.674E-3 5.935E-3 2.164E-2
7.716E-2
 2 224
14 GO:0009897 external side of plasma membrane 6.920E-3 1.038E-2 3.784E-2
1.453E-1
 2 310
15 GO:0030670 phagocytic vesicle membrane 2.491E-2 3.488E-2
1.271E-1
5.231E-1
 1 60
16 GO:0045335 phagocytic vesicle 3.635E-2 4.771E-2
1.739E-1
7.633E-1
 1 88
Show 11 more annotations

4: Human Phenotype [Display Chart] 4 input genes in category / 67 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0100759 Clubbing of fingers 1.132E-4 7.132E-3 3.416E-2 7.581E-3 2 21
2 HP:0006519 Alveolar cell carcinoma 2.835E-4 7.132E-3 3.416E-2 1.900E-2 2 33
3 HP:0100552 Neoplasm of the tracheobronchial system 3.193E-4 7.132E-3 3.416E-2 2.139E-2 2 35
4 HP:0011945 Bronchiolitis obliterans organizing pneumonia 7.924E-4 1.327E-2
6.357E-2
5.309E-2
 2 55
5 HP:0006516 Hypersensitivity pneumonitis 1.247E-3 1.671E-2
8.002E-2
8.354E-2
 2 69
6 HP:0001217 Clubbing 1.592E-3 1.778E-2
8.514E-2
1.067E-1
 2 78
7 HP:0001211 Abnormal fingertip morphology 2.307E-3 2.208E-2
1.057E-1
1.545E-1
 2 94
8 HP:0006510 Chronic obstructive pulmonary disease 3.321E-3 2.516E-2
1.205E-1
2.225E-1
 2 113
9 HP:0002875 Exertional dyspnea 3.380E-3 2.516E-2
1.205E-1
2.264E-1
 2 114
10 HP:0006515 Interstitial pneumonitis 4.118E-3 2.759E-2
1.321E-1
2.759E-1
 2 126
11 HP:0011950 Bronchiolitis 4.856E-3 2.958E-2
1.417E-1
3.253E-1
 2 137
12 HP:0011948 Acute respiratory tract infection 5.503E-3 3.072E-2
1.472E-1
3.687E-1
 2 146
13 HP:0006536 Obstructive lung disease 6.346E-3 3.093E-2
1.482E-1
4.252E-1
 2 157
14 HP:0100526 Neoplasm of the lung 6.586E-3 3.093E-2
1.482E-1
4.413E-1
 2 160
15 HP:0100606 Neoplasm of the respiratory system 6.995E-3 3.093E-2
1.482E-1
4.687E-1
 2 165
16 HP:0006528 Chronic lung disease 7.762E-3 3.093E-2
1.482E-1
5.200E-1
 2 174
17 HP:0002206 Pulmonary fibrosis 7.849E-3 3.093E-2
1.482E-1
5.259E-1
 2 175
18 HP:0010702 Increased antibody level in blood 9.216E-3 3.431E-2
1.643E-1
6.175E-1
 2 190
19 HP:0002097 Emphysema 1.019E-2 3.592E-2
1.720E-1
6.824E-1
 2 200
20 HP:0002020 Gastroesophageal reflux 1.258E-2 4.111E-2
1.969E-1
8.432E-1
 2 223
21 HP:0004890 Elevated pulmonary artery pressure 1.359E-2 4.111E-2
1.969E-1
9.104E-1
 2 232
22 HP:0002092 Pulmonary arterial hypertension 1.359E-2 4.111E-2
1.969E-1
9.104E-1
 2 232
23 HP:0006530 Interstitial pulmonary abnormality 1.428E-2 4.111E-2
1.969E-1
9.565E-1
 2 238
24 HP:0001394 Cirrhosis 1.498E-2 4.111E-2
1.969E-1
1.000E0
 2 244
25 HP:0003881 Humeral sclerosis 1.534E-2 4.111E-2
1.969E-1
1.000E0
 2 247
26 HP:0006392 Increased density of long bones 1.668E-2 4.299E-2
2.059E-1
1.000E0
 2 258
27 HP:0100032 Immunoglobulin abnormality 1.966E-2 4.563E-2
2.185E-1
1.000E0
 2 281
28 HP:0010701 Abnormal immunoglobulin level 1.966E-2 4.563E-2
2.185E-1
1.000E0
 2 281
29 HP:0005372 Abnormality of B cell physiology 1.980E-2 4.563E-2
2.185E-1
1.000E0
 2 282
30 HP:0003063 Abnormality of the humerus 2.187E-2 4.563E-2
2.185E-1
1.000E0
 2 297
31 HP:0030875 Abnormality of pulmonary circulation 2.229E-2 4.563E-2
2.185E-1
1.000E0
 2 300
32 HP:0001454 Abnormality of the upper arm 2.229E-2 4.563E-2
2.185E-1
1.000E0
 2 300
33 HP:0010738 Osteosclerosis 2.315E-2 4.563E-2
2.185E-1
1.000E0
 2 306
34 HP:0005711 Generalized osteosclerosis 2.315E-2 4.563E-2
2.185E-1
1.000E0
 2 306
35 HP:0004414 Abnormality of the pulmonary artery 2.628E-2 4.899E-2
2.346E-1
1.000E0
 2 327
36 HP:0003346 Abnormal immunological laboratory finding 2.675E-2 4.899E-2
2.346E-1
1.000E0
 2 330
37 HP:0030163 Abnormal vascular physiology 2.706E-2 4.899E-2
2.346E-1
1.000E0
 2 332
Show 32 more annotations

5: Mouse Phenotype [Display Chart] 6 input genes in category / 349 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0008245 abnormal alveolar macrophage morphology 3.791E-5 1.323E-2
8.512E-2
 1.323E-2 2 17
2 MP:0020185 altered susceptibility to viral infection 1.011E-4 1.764E-2
1.135E-1
 3.527E-2 3 181
3 MP:0001179 thick pulmonary interalveolar septum 3.386E-4 3.074E-2
1.977E-1
1.182E-1
 2 50
4 MP:0004782 abnormal surfactant physiology 3.523E-4 3.074E-2
1.977E-1
1.229E-1
 2 51
5 MP:0010900 abnormal pulmonary interalveolar septum morphology 4.879E-4 3.406E-2
2.191E-1
1.703E-1
 2 60
6 MP:0004777 abnormal phospholipid level 6.266E-4 3.483E-2
2.241E-1
2.187E-1
 2 68
7 MP:0008721 abnormal chemokine level 8.240E-4 3.483E-2
2.241E-1
2.876E-1
 2 78
8 MP:0010898 abnormal pulmonary alveolus epithelium morphology 8.883E-4 3.483E-2
2.241E-1
3.100E-1
 2 81
9 MP:0008652 decreased interleukin-1 secretion 1.159E-3 3.483E-2
2.241E-1
4.043E-1
 1 2
10 MP:0010022 brain vascular congestion 1.159E-3 3.483E-2
2.241E-1
4.043E-1
 1 2
11 MP:0010901 abnormal pulmonary alveolar parenchyma morphology 1.220E-3 3.483E-2
2.241E-1
4.257E-1
 2 95
12 MP:0002451 abnormal macrophage physiology 1.330E-3 3.483E-2
2.241E-1
4.642E-1
 3 434
13 MP:0008713 abnormal cytokine level 1.375E-3 3.483E-2
2.241E-1
4.800E-1
 3 439
14 MP:0002406 increased susceptibility to infection 1.468E-3 3.483E-2
2.241E-1
5.125E-1
 3 449
15 MP:0008835 abnormal intercellular signaling peptide or protein level 1.497E-3 3.483E-2
2.241E-1
5.225E-1
 3 452
Show 10 more annotations

6: Domain [Display Chart] 8 input genes in category / 41 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS00615 C TYPE LECTIN 1 PROSITE 1.393E-13 1.786E-12 7.683E-12 5.710E-12 6 80
2 SM00034 CLECT SMART 1.883E-13 1.786E-12 7.683E-12 7.720E-12 6 84
3 PF00059 Lectin C Pfam 1.883E-13 1.786E-12 7.683E-12 7.720E-12 6 84
4 PS50041 C TYPE LECTIN 2 PROSITE 2.026E-13 1.786E-12 7.683E-12 8.306E-12 6 85
5 IPR001304 C-type lectin-like InterPro 2.178E-13 1.786E-12 7.683E-12 8.928E-12 6 86
6 3.10.100.10 - Gene3D 4.572E-13 3.036E-12 1.306E-11 1.875E-11 6 97
7 IPR016186 C-type lectin-like/link InterPro 5.184E-13 3.036E-12 1.306E-11 2.125E-11 6 99
8 IPR016187 CTDL fold InterPro 8.354E-13 4.282E-12 1.842E-11 3.425E-11 6 107
9 IPR018378 C-type lectin CS InterPro 6.256E-7 2.850E-6 1.226E-5 2.565E-5 3 43
10 PF01391 Collagen Pfam 4.965E-6 1.851E-5 7.963E-5 2.036E-4 3 85
11 IPR008160 Collagen InterPro 4.965E-6 1.851E-5 7.963E-5 2.036E-4 3 85
12 PF09006 Surfac D-trimer Pfam 4.270E-4 1.167E-3 5.022E-3 1.751E-2 1 1
13 IPR027185 TLR2 InterPro 4.270E-4 1.167E-3 5.022E-3 1.751E-2 1 1
14 1.20.5.360 - Gene3D 4.270E-4 1.167E-3 5.022E-3 1.751E-2 1 1
15 IPR015097 Surfac D-trimer InterPro 4.270E-4 1.167E-3 5.022E-3 1.751E-2 1 1
16 IPR017241 Toll-like receptor InterPro 2.133E-3 5.467E-3 2.352E-2
8.747E-2
 1 5
17 SM00255 TIR SMART 8.934E-3 2.075E-2
8.928E-2
3.663E-1
 1 21
18 PF01582 TIR Pfam 9.357E-3 2.075E-2
8.928E-2
3.837E-1
 1 22
19 3.40.50.10140 - Gene3D 9.781E-3 2.075E-2
8.928E-2
4.010E-1
 1 23
20 PS50104 TIR PROSITE 1.020E-2 2.075E-2
8.928E-2
4.184E-1
 1 24
21 IPR000157 TIR dom InterPro 1.063E-2 2.075E-2
8.928E-2
4.357E-1
 1 25
22 PF01463 LRRCT Pfam 1.359E-2 2.532E-2
1.089E-1
5.570E-1
 1 32
23 PF07654 C1-set Pfam 2.283E-2 4.019E-2
1.729E-1
9.361E-1
 1 54
24 SM00407 IGc1 SMART 2.367E-2 4.019E-2
1.729E-1
9.704E-1
 1 56
25 IPR003597 Ig C1-set InterPro 2.450E-2 4.019E-2
1.729E-1
1.000E0
 1 58
Show 20 more annotations

7: Pathway [Display Chart] 8 input genes in category / 60 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1339131 Defective ABCA3 causes pulmonary surfactant metabolism dysfunction type 3 (SMDP3) BioSystems: REACTOME 1.741E-9 1.044E-7 4.887E-7 1.044E-7 3 5
2 1309214 Defective CSF2RA causes pulmonary surfactant metabolism dysfunction 4 (SMDP4) BioSystems: REACTOME 9.738E-9 1.948E-7 9.115E-7 5.843E-7 3 8
3 1309215 Defective CSF2RB causes pulmonary surfactant metabolism dysfunction 5 (SMDP5) BioSystems: REACTOME 9.738E-9 1.948E-7 9.115E-7 5.843E-7 3 8
4 1309208 Diseases associated with surfactant metabolism BioSystems: REACTOME 2.085E-8 2.997E-7 1.403E-6 1.251E-6 3 10
5 M5880 Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins MSigDB C2 BIOCARTA (v6.0) 2.497E-8 2.997E-7 1.403E-6 1.498E-6 5 171
6 1309210 Defective SFTPA2 causes idiopathic pulmonary fibrosis (IPF) BioSystems: REACTOME 3.613E-7 3.613E-6 1.691E-5 2.168E-5 2 2
7 1309223 Surfactant metabolism BioSystems: REACTOME 7.013E-7 6.011E-6 2.813E-5 4.208E-5 3 30
8 153910 Phagosome BioSystems: KEGG 1.516E-6 1.137E-5 5.323E-5 9.099E-5 4 154
9 137979 FOXA1 transcription factor network BioSystems: Pathway Interaction Database 2.123E-6 1.416E-5 6.625E-5 1.274E-4 3 43
10 1268939 Diseases of metabolism BioSystems: REACTOME 2.440E-6 1.464E-5 6.852E-5 1.464E-4 3 45
11 1268933 ABC transporter disorders BioSystems: REACTOME 9.752E-6 5.319E-5 2.489E-4 5.851E-4 3 71
12 1268932 Disorders of transmembrane transporters BioSystems: REACTOME 1.295E-5 6.476E-5 3.031E-4 7.771E-4 3 78
13 152665 Malaria BioSystems: KEGG 4.185E-4 1.932E-3 9.040E-3 2.511E-2 2 49
14 218111 Pertussis BioSystems: KEGG 1.006E-3 4.309E-3 2.017E-2
6.033E-2
 2 76
15 1269201 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell BioSystems: REACTOME 3.177E-3 1.271E-2
5.947E-2
1.906E-1
 2 136
16 1269158 IRAK4 deficiency (TLR2/4) BioSystems: REACTOME 7.048E-3 2.349E-2
1.100E-1
4.229E-1
 1 11
17 PW:0000234 innate immune response Pathway Ontology 7.048E-3 2.349E-2
1.100E-1
4.229E-1
 1 11
18 1269160 MyD88 deficiency (TLR2/4) BioSystems: REACTOME 7.048E-3 2.349E-2
1.100E-1
4.229E-1
 1 11
19 1270241 Signal regulatory protein (SIRP) family interactions BioSystems: REACTOME 8.325E-3 2.629E-2
1.230E-1
4.995E-1
 1 13
20 1427857 Regulation of TLR by endogenous ligand BioSystems: REACTOME 1.024E-2 3.071E-2
1.437E-1
6.143E-1
 1 16
21 M9177 Dendritic cells in regulating TH1 and TH2 Development MSigDB C2 BIOCARTA (v6.0) 1.405E-2 3.831E-2
1.793E-1
8.432E-1
 1 22
22 1269157 Diseases associated with the TLR signaling cascade BioSystems: REACTOME 1.532E-2 3.831E-2
1.793E-1
9.193E-1
 1 24
23 1269156 Diseases of Immune System BioSystems: REACTOME 1.532E-2 3.831E-2
1.793E-1
9.193E-1
 1 24
24 M2821 NFkB activation by Nontypeable Hemophilus influenzae MSigDB C2 BIOCARTA (v6.0) 1.532E-2 3.831E-2
1.793E-1
9.193E-1
 1 24
Show 19 more annotations

8: Pubmed [Display Chart] 8 input genes in category / 3934 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 23183169 Mice deficient in surfactant protein A (SP-A) and SP-D or in TLR2 manifest delayed parturition and decreased expression of inflammatory and contractile genes. Pubmed 6.031E-12 5.932E-9 5.253E-8 2.373E-8 3 3
2 18983439 Surfactant protein A and D gene polymorphisms and protein expression in victims of sudden infant death. Pubmed 6.031E-12 5.932E-9 5.253E-8 2.373E-8 3 3
3 24960334 Eosinophil-associated lung diseases. A cry for surfactant proteins A and D help? Pubmed 6.031E-12 5.932E-9 5.253E-8 2.373E-8 3 3
4 21601013 SP-A1, SP-A2 and SP-D gene polymorphisms in severe acute respiratory syncytial infection in Chilean infants. Pubmed 6.031E-12 5.932E-9 5.253E-8 2.373E-8 3 3
5 18287966 Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pubmed 7.233E-10 5.691E-7 5.039E-6 2.845E-6 3 10
6 21865055 Surfactant protein A modulates the lipopolysaccharide-induced inflammatory response related to preterm birth. Pubmed 1.326E-9 8.692E-7 7.697E-6 5.215E-6 3 12
7 29212911 A Role of NKR-P1A (CD161) and Lectin-like Transcript 1 in Natural Cytotoxicity against Human Articular Chondrocytes. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
8 12858173 Genetically linked C-type lectin-related ligands for the NKRP1 family of natural killer cell receptors. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
9 21572041 Molecular basis for LLT1 protein recognition by human CD161 protein (NKRP1A/KLRB1). Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
10 26421960 Expression of surfactant proteins SP-A and SP-D in murine decidua and immunomodulatory effects on decidual macrophages. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
11 19287351 Transmission of surfactant protein variants and haplotypes in children hospitalized with respiratory syncytial virus. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
12 26849628 Surfactant Proteins SP-A and SP-D Ameliorate Pneumonia Severity and Intestinal Injury in a Murine Model of Staphylococcus Aureus Pneumonia. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
13 16406431 [Pseudomonas aeruginosa and Surfactant-associated Proteins A and D]. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
14 10423401 Characterization of the mouse collectin gene locus. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
15 28351530 Structure, genetics and function of the pulmonary associated surfactant proteins A and D: The extra-pulmonary role of these C type lectins. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
16 20413160 Susceptibility of mice genetically deficient in SP-A or SP-D gene to invasive pulmonary aspergillosis. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
17 10047533 Lung surfactant proteins involved in innate immunity. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
18 15280465 Pulmonary collectins modulate strain-specific influenza a virus infection and host responses. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
19 16213021 Surfactant proteins SP-A and SP-D: structure, function and receptors. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
20 20693318 Human SP-A1 (SFTPA1) variant-specific 3' UTRs and poly(A) tail differentially affect the in vitro translation of a reporter gene. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
21 17580966 Effect of cysteine 85 on biochemical properties and biological function of human surfactant protein A variants. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
22 2610270 Studies of the structure of lung surfactant protein SP-A. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
23 11087951 Structural characterisation of human proteinosis surfactant protein A. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
24 23069847 Genetic complexity of the human surfactant-associated proteins SP-A1 and SP-A2. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
25 25255378 Role of surfactant proteins A and D in sepsis-induced acute kidney injury. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
26 17874049 Immunohistochemical distribution of SP-D, compared with that of SP-A and KL-6, in interstitial pneumonias. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
27 12015304 The role of pulmonary collectin N-terminal domains in surfactant structure, function, and homeostasis in vivo. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
28 17524024 Haplotypes of the surfactant protein genes A and D as susceptibility factors for the development of respiratory distress syndrome. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
29 12376353 Sequential targeted deficiency of SP-A and -D leads to progressive alveolar lipoproteinosis and emphysema. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
30 20963503 Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
31 24984162 Correlation analysis between single nucleotide polymorphisms of pulmonary surfactant protein A gene and pulmonary tuberculosis in the Han population in China. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
32 20048345 Humanized SFTPA1 and SFTPA2 transgenic mice reveal functional divergence of SP-A1 and SP-A2: formation of tubular myelin in vivo requires both gene products. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
33 12857753 Macrophage-independent fungicidal action of the pulmonary collectins. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
34 21199913 Dispensability of surfactant proteins A and D in immune control of Mycobacterium tuberculosis infection following aerosol challenge of mice. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
35 16339513 Cutting edge: lectin-like transcript-1 is a ligand for the inhibitory human NKR-P1A receptor. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
36 23038062 Surfactant protein A associated with respiratory distress syndrome in Korean preterm infants: evidence of ethnic difference. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
37 16339512 Cutting edge: lectin-like transcript 1 is a ligand for the CD161 receptor. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
38 24793167 An 11-nt sequence polymorphism at the 3'UTR of human SFTPA1 and SFTPA2 gene variants differentially affect gene expression levels and miRNA regulation in cell culture. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
39 12817025 Direct binding of Toll-like receptor 2 to zymosan, and zymosan-induced NF-kappa B activation and TNF-alpha secretion are down-regulated by lung collectin surfactant protein A. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
40 24954098 Sex differences in the acute in vivo effects of different human SP-A variants on the mouse alveolar macrophage proteome. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
41 12654643 Pseudomonas aeruginosa elastase degrades surfactant proteins A and D. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
42 1372511 Characterization of a second human pulmonary surfactant-associated protein SP-A gene. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
43 8406480 Assignment of the human pulmonary surfactant protein D gene (SFTP4) to 10q22-q23 close to the surfactant protein A gene cluster. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
44 20056602 Pulmonary collectins protect macrophages against pore-forming activity of Legionella pneumophila and suppress its intracellular growth. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
45 28791362 Correlation analysis of surfactant protein A and surfactant protein D with lung function in exhaled breath condensate from lung cancer patients with and without COPD. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
46 15608147 Cooperative anti-influenza activities of respiratory innate immune proteins and neuraminidase inhibitor. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
47 15274124 High resolution mass spectrometric alveolar proteomics: identification of surfactant protein SP-A and SP-D modifications in proteinosis and cystic fibrosis patients. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
48 27835691 Surfactant Protein A and B Gene Polymorphisms and Risk of Respiratory Distress Syndrome in Late-Preterm Neonates. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
49 27626681 Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
50 8226864 A different combination of transcription factors modulates the expression of the human transferrin promoter in liver and Sertoli cells. Pubmed 3.839E-8 2.158E-6 1.910E-5 1.510E-4 2 2
Show 45 more annotations

9: Interaction [Display Chart] 8 input genes in category / 146 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:SFTPA1 SFTPA1 interactions 1.197E-12 1.747E-10 9.723E-10 1.747E-10 4 8
2 int:KLRB1 KLRB1 interactions 1.072E-6 7.823E-5 4.353E-4 1.565E-4 2 4
3 int:SFTPA2 SFTPA2 interactions 1.786E-6 8.691E-5 4.836E-4 2.607E-4 2 5
4 int:SFTPD SFTPD interactions 3.748E-6 1.368E-4 7.613E-4 5.473E-4 2 7
5 int:DMBT1 DMBT1 interactions 2.138E-5 6.242E-4 3.473E-3 3.121E-3 2 16
6 int:TLR2 TLR2 interactions 1.055E-4 2.568E-3 1.429E-2 1.541E-2 2 35
7 int:CLEC2D CLEC2D interactions 5.008E-4 9.140E-3
5.086E-2
7.312E-2
 2 76
8 int:NR0B2 NR0B2 interactions 5.008E-4 9.140E-3
5.086E-2
7.312E-2
 2 76
9 int:CLEC1B CLEC1B interactions 1.807E-3 2.579E-2
1.435E-1
2.638E-1
 1 4
10 int:SIRPG SIRPG interactions 1.807E-3 2.579E-2
1.435E-1
2.638E-1
 1 4
11 int:KIAA1586 KIAA1586 interactions 2.258E-3 2.579E-2
1.435E-1
3.296E-1
 1 5
12 int:PTPN6 PTPN6 interactions 2.646E-3 2.579E-2
1.435E-1
3.863E-1
 2 176
13 int:TLR6 TLR6 interactions 2.709E-3 2.579E-2
1.435E-1
3.955E-1
 1 6
14 int:MFAP4 MFAP4 interactions 3.160E-3 2.579E-2
1.435E-1
4.613E-1
 1 7
15 int:LY96 LY96 interactions 3.160E-3 2.579E-2
1.435E-1
4.613E-1
 1 7
16 int:ADGRL3 ADGRL3 interactions 3.610E-3 2.579E-2
1.435E-1
5.271E-1
 1 8
17 int:CLEC4M CLEC4M interactions 4.061E-3 2.579E-2
1.435E-1
5.929E-1
 1 9
18 int:SV2A SV2A interactions 4.511E-3 2.579E-2
1.435E-1
6.586E-1
 1 10
19 int:TM9SF1 TM9SF1 interactions 4.511E-3 2.579E-2
1.435E-1
6.586E-1
 1 10
20 int:TMEM68 TMEM68 interactions 4.511E-3 2.579E-2
1.435E-1
6.586E-1
 1 10
21 int:NXPE3 NXPE3 interactions 4.961E-3 2.579E-2
1.435E-1
7.243E-1
 1 11
22 int:ECEL1 ECEL1 interactions 4.961E-3 2.579E-2
1.435E-1
7.243E-1
 1 11
23 int:TLR10 TLR10 interactions 5.411E-3 2.579E-2
1.435E-1
7.900E-1
 1 12
24 int:SLC2A8 SLC2A8 interactions 5.861E-3 2.579E-2
1.435E-1
8.557E-1
 1 13
25 int:SUSD1 SUSD1 interactions 6.310E-3 2.579E-2
1.435E-1
9.213E-1
 1 14
26 int:GLRB GLRB interactions 6.310E-3 2.579E-2
1.435E-1
9.213E-1
 1 14
27 int:ATP8B2 ATP8B2 interactions 6.760E-3 2.579E-2
1.435E-1
9.869E-1
 1 15
28 int:ST6GALNAC3 ST6GALNAC3 interactions 6.760E-3 2.579E-2
1.435E-1
9.869E-1
 1 15
29 int:C17orf75 C17orf75 interactions 6.760E-3 2.579E-2
1.435E-1
9.869E-1
 1 15
30 int:DYNC2LI1 DYNC2LI1 interactions 6.760E-3 2.579E-2
1.435E-1
9.869E-1
 1 15
31 int:SLC7A3 SLC7A3 interactions 7.209E-3 2.579E-2
1.435E-1
1.000E0
 1 16
32 int:SLC22A23 SLC22A23 interactions 7.209E-3 2.579E-2
1.435E-1
1.000E0
 1 16
33 int:FASTKD1 FASTKD1 interactions 7.658E-3 2.579E-2
1.435E-1
1.000E0
 1 17
34 int:TLR1 TLR1 interactions 8.107E-3 2.579E-2
1.435E-1
1.000E0
 1 18
35 int:BACE2 BACE2 interactions 8.107E-3 2.579E-2
1.435E-1
1.000E0
 1 18
36 int:ATP7B ATP7B interactions 8.107E-3 2.579E-2
1.435E-1
1.000E0
 1 18
37 int:GPR50 GPR50 interactions 8.107E-3 2.579E-2
1.435E-1
1.000E0
 1 18
38 int:LARGE2 LARGE2 interactions 8.556E-3 2.579E-2
1.435E-1
1.000E0
 1 19
39 int:STARD3 STARD3 interactions 9.004E-3 2.579E-2
1.435E-1
1.000E0
 1 20
40 int:TMEM184B TMEM184B interactions 9.004E-3 2.579E-2
1.435E-1
1.000E0
 1 20
41 int:ABCB6 ABCB6 interactions 9.004E-3 2.579E-2
1.435E-1
1.000E0
 1 20
42 int:STK11IP STK11IP interactions 9.004E-3 2.579E-2
1.435E-1
1.000E0
 1 20
43 int:SLC25A20 SLC25A20 interactions 9.452E-3 2.579E-2
1.435E-1
1.000E0
 1 21
44 int:ARFGEF3 ARFGEF3 interactions 9.452E-3 2.579E-2
1.435E-1
1.000E0
 1 21
45 int:CLEC7A CLEC7A interactions 9.901E-3 2.579E-2
1.435E-1
1.000E0
 1 22
46 int:FRMD5 FRMD5 interactions 9.901E-3 2.579E-2
1.435E-1
1.000E0
 1 22
47 int:EVI5L EVI5L interactions 9.901E-3 2.579E-2
1.435E-1
1.000E0
 1 22
48 int:SIRPA SIRPA interactions 1.035E-2 2.579E-2
1.435E-1
1.000E0
 1 23
49 int:CD22 CD22 interactions 1.035E-2 2.579E-2
1.435E-1
1.000E0
 1 23
50 int:NARS2 NARS2 interactions 1.035E-2 2.579E-2
1.435E-1
1.000E0
 1 23
Show 45 more annotations

10: Cytoband [Display Chart] 8 input genes in category / 6 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 10q22.3 10q22.3 4.800E-5 2.880E-4 7.056E-4 2.880E-4 2 46
2 12p13 12p13 9.925E-5 2.978E-4 7.295E-4 5.955E-4 2 66
3 10q22.2-q23.1 10q22.2-q23.1 2.308E-4 4.616E-4 1.131E-3 1.385E-3 1 1
4 4q32 4q32 1.384E-3 2.076E-3 5.087E-3 8.305E-3 1 6
5 12p13.2 12p13.2 1.103E-2 1.323E-2 3.242E-2
6.616E-2
 1 48
6 20p13 20p13 2.330E-2 2.330E-2
5.709E-2
1.398E-1
 1 102
Show 1 more annotation

11: Transcription Factor Binding Site [Display Chart] 1 input genes in category / 1 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$CEBPB 01 V$CEBPB 01 2.129E-2 2.129E-2 2.129E-2 2.129E-2 1 208

12: Gene Family [Display Chart] 8 input genes in category / 9 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 491 Collectins|Scavenger receptors|C-type lectin domain containing genenames.org 6.686E-9 6.018E-8 1.702E-7 6.018E-8 3 10
2 1298 C-type lectin domain containing genenames.org 5.902E-7 2.656E-6 7.513E-6 5.312E-6 3 41
3 494 C-type lectin domain family genenames.org 8.966E-7 2.690E-6 7.609E-6 8.069E-6 3 47
4 471 CD molecules|Tumor necrosis factor superfamily genenames.org 5.205E-4 1.171E-3 3.313E-3 4.685E-3 3 394
5 747 Signal regulatory proteins genenames.org 2.636E-3 4.744E-3 1.342E-2 2.372E-2 1 6
6 948 CD molecules|Toll like receptors genenames.org 4.389E-3 6.584E-3 1.863E-2 3.951E-2 1 10
7 621 CD molecules|Killer cell lectin like receptors|C-type lectin domain containing genenames.org 5.265E-3 6.770E-3 1.915E-2 4.739E-2 1 12
8 591 Histocompatibility complex|C1-set domain containing genenames.org 1.832E-2 2.061E-2
5.831E-2
1.649E-1
 1 42
Show 3 more annotations

13: Coexpression [Display Chart] 8 input genes in category / 715 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M18630 Genes in the most frequently homozygous deleted loci in a panel of glioma cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.674E-7 4.772E-4 3.412E-3 4.772E-4 3 54
2 20460173-ImmPortAntimicrobials Human Immune Kong10 544genes ImmPort Antimicrobials GeneSigDB 1.094E-5 3.804E-3 2.720E-2 7.821E-3 4 469
3 16289389-Table2a Human Lung Hoang05 18genes GeneSigDB 1.596E-5 3.804E-3 2.720E-2 1.141E-2 2 18
4 M8676 Genes up-regulated in monocytes (24h): M. tuberculosis 19 kDa lipopeptide versus M. tuberculosis 19 kDa lipopeptide and muramyl dipeptide [PubChem=11620162]. MSigDB C7: Immunologic Signatures (v6.0) 3.349E-5 4.862E-3 3.476E-2 2.395E-2 3 198
5 M8686 Genes down-regulated in monocytes (6h): muramyl dipeptide [PubChem=11620162] versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 3.400E-5 4.862E-3 3.476E-2 2.431E-2 3 199
6 M14829 Genes down-regulated in hematopoietic precursor cells conditionally expressing HOXA9 and MEIS1 [GeneID=3205;4211]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.022E-4 3.425E-2
2.449E-1
2.160E-1
 2 77
7 M215 Selected genes up-regulated in prostate tumors developed by transgenic mice overexpressing VAV3 [GeneID=10451] in prostate epithelium. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.036E-4 3.425E-2
2.449E-1
2.885E-1
 2 89
8 M7111 Genes up-regulated in CD4 [GeneID=920] T cells: control versus treated with halofuginone [PubChem=400772] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 8.320E-4 3.425E-2
2.449E-1
5.949E-1
 2 128
9 M9117 Genes down-regulated in CD4 T conv: control versus over-expression of XBP1 and FOXP3 [GeneID=7494;50943]. MSigDB C7: Immunologic Signatures (v6.0) 1.200E-3 3.425E-2
2.449E-1
8.583E-1
 2 154
10 M12138 Genes up-regulated in erythroid lineage cells by RUNX1-RUNX1T1 [GeneID=861;862] fusion . MSigDB C2: CGP Curated Gene Sets (v6.0) 1.247E-3 3.425E-2
2.449E-1
8.918E-1
 2 157
11 16289389-TableS1 Human Lung Hoang05 181genes GeneSigDB 1.247E-3 3.425E-2
2.449E-1
8.918E-1
 2 157
12 M5640 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute influenza infection. MSigDB C7: Immunologic Signatures (v6.0) 1.295E-3 3.425E-2
2.449E-1
9.258E-1
 2 160
13 M1430 Genes defining differentiation potential of the bipotential myeloid cell line FDB. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.376E-3 3.425E-2
2.449E-1
9.839E-1
 2 165
14 M5644 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 1.409E-3 3.425E-2
2.449E-1
1.000E0
 2 167
15 M6816 Genes down-regulated in immature dendritic cells: untreated versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 1.443E-3 3.425E-2
2.449E-1
1.000E0
 2 169
16 M5660 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute E. coli infection versus PBMC from patients with acute S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 1.494E-3 3.425E-2
2.449E-1
1.000E0
 2 172
17 M12824 Cluster 4 of method A: up-regulation of these genes in patients with non-small cell lung cancer (NSCLC) predicts good survival outcome. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.933E-3 3.425E-2
2.449E-1
1.000E0
 2 196
18 M2155 Genes up-regulated during pubertal mammary gland development between week 6 and 7. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.953E-3 3.425E-2
2.449E-1
1.000E0
 2 197
19 M7972 Genes down-regulated in bone marrow-derived macrophages with PPARG [GeneID=5468] knockout treated with IL4 [GeneID=3565]: control versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.953E-3 3.425E-2
2.449E-1
1.000E0
 2 197
20 M9578 Genes up-regulated in T reg: peripheral lymph nodes versus thymic CD24 low [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 1.972E-3 3.425E-2
2.449E-1
1.000E0
 2 198
21 M8674 Genes up-regulated in monocytes (24h): untreated versus muramyl dipeptide [PubChem=11620162] andM. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 1.972E-3 3.425E-2
2.449E-1
1.000E0
 2 198
22 M4055 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 1.992E-3 3.425E-2
2.449E-1
1.000E0
 2 199
23 M8672 Genes up-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 1.992E-3 3.425E-2
2.449E-1
1.000E0
 2 199
24 M3078 Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
25 M3088 Genes down-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
26 M4480 Genes down-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus monocytes cultured for 0 days. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
27 M4496 Genes down-regulated in comparison of naive CD8 T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
28 M4494 Genes up-regulated in comparison of naive CD8 T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
29 M6468 Genes down-regulated in CD4 [GeneID=920] T cells versus B1 B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
30 M3082 Genes down-regulated in comparison of healthy B cells versus healthy myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
31 M3087 Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
32 M4354 Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 24 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 24 h. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
33 M3891 Genes down-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
34 M3276 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) cultured with YF17D vaccine for 12 h versus PBMC cultured for 3 h. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
35 M10028 Genes up-regulated in NK cells versus CD8A [GeneID=925] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
36 M3091 Genes down-regulated in comparison of systemic lupus erythematosus B cells versus systemic lupus erythromatosus myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
37 M4963 Genes up-regulated in comparison of monocytes from influenza vaccinee at day 7 post-vaccination versus plasmacytoid dendritic cells (mDC) at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
38 M4506 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus day 0 monocytes. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
39 M4971 Genes down-regulated in comparison of plasmacytoid dendritic cells (DC) from influenza vaccinee at day 7 post-vaccination versus myeloid DCs at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
40 M4945 Genes up-regulated in comparison of monocytes versus plasmacytoid dendritic cells (pDC). MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
41 M4624 Genes down-regulated in comparison of untreated CD25+ T effector cells at day 7 versus untreated CD25- T cells at day 7. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
42 M9851 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4intermediate versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 2.012E-3 3.425E-2
2.449E-1
1.000E0
 2 200
43 M14539 Genes up-regulated in medullary breast cancer (MBC) relative to ductal breast cancer (DBD). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.132E-3 3.498E-2
2.501E-1
1.000E0
 2 206
44 19795415-Table1 Mouse Lung Beisiegel09 262genes GeneSigDB 2.153E-3 3.498E-2
2.501E-1
1.000E0
 2 207
45 M1306 Genes up-regulated in SEND cells (skin endothelium) at normal oxygen (normoxia) conditions after knockdown of HIF1A [GeneID=3091] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.763E-3 4.390E-2
3.139E-1
1.000E0
 1 8
46 M4502 Genes down-regulated in leukemic stem cells (LSC), defined as CD34+CD38- [GeneID=947;952] cells from AML (acute myeloid leukemia patients) compared to the CD34+CD38+ cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.974E-3 4.623E-2
3.305E-1
1.000E0
 2 244
Show 41 more annotations

14: Coexpression Atlas [Display Chart] 8 input genes in category / 794 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Sample Type by Project: Shred 1/TCGA-Thymus/Thymoma/Type A/2/3 Sample Type by Project: Shred 1/TCGA-Thymus/Thymoma/Type A/2/3 TCGA-Thymus 5.782E-6 1.913E-3 1.388E-2 4.591E-3 3 104
2 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma/Malignant Peripheral Nerve Sheath Tumors /0 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma/Malignant Peripheral Nerve Sheath Tumors /0 TCGA-Bone and Soft Tissue 7.227E-6 1.913E-3 1.388E-2 5.738E-3 3 112
3 Sample Type by Project: Shred 1/TCGA-Thryoid/Thyroid Papillary Carcinoma /Diffuse Sclerosing /2 Sample Type by Project: Shred 1/TCGA-Thryoid/Thyroid Papillary Carcinoma /Diffuse Sclerosing /2 TCGA-Thryoid 7.227E-6 1.913E-3 1.388E-2 5.738E-3 3 112
4 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Papillary Adenocarcinoma/5/3 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Papillary Adenocarcinoma/5/3 TCGA-Lung 1.353E-5 2.596E-3 1.883E-2 1.074E-2 3 138
5 Sample Type by Project: Shred 1/TCGA-Thymus/Thymoma/Type B3/1/2 Sample Type by Project: Shred 1/TCGA-Thymus/Thymoma/Type B3/1/2 TCGA-Thymus 1.635E-5 2.596E-3 1.883E-2 1.298E-2 3 147
6 Sample Type by Project: Shred 1/TCGA-Mesothelium/Mesothelioma/Epitheliod/3/1 Sample Type by Project: Shred 1/TCGA-Mesothelium/Mesothelioma/Epitheliod/3/1 TCGA-Mesothelium 2.754E-5 3.512E-3 2.548E-2 2.186E-2 3 175
7 lung lung Human Protein Atlas 3.096E-5 3.512E-3 2.548E-2 2.458E-2 3 182
8 GSM854269 500 Myeloid Cells, DC.103-11b+24+.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24+, Lung, avg-2 Immgen.org, GSE15907 3.288E-4 2.086E-2
1.513E-1
2.611E-1
 3 404
9 gudmap kidney e15.5 SmlBldVes Tie2 500 kidney e15.5 SmlBldVes Tie2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.508E-4 2.086E-2
1.513E-1
2.785E-1
 3 413
10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Tumour RCC Renal cell carcinoma/Kidney Tumour RCC T12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Tumour RCC Renal cell carcinoma/Kidney Tumour RCC T12 Adult, Development, and Cancer types 3.665E-4 2.086E-2
1.513E-1
2.910E-1
 1 1
11 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-U/Kidney Tumour RCC EN-U/Kidney Tumour RCC EN10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-U/Kidney Tumour RCC EN-U/Kidney Tumour RCC EN10 Adult, Development, and Cancer types 3.665E-4 2.086E-2
1.513E-1
2.910E-1
 1 1
12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Private/Kidney Tumour Wilms Private/Kidney Tumour Wilms IN12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Private/Kidney Tumour Wilms Private/Kidney Tumour Wilms IN12 Adult, Development, and Cancer types 3.665E-4 2.086E-2
1.513E-1
2.910E-1
 1 1
13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal-Medulla Wilms Endothelium/Kidney Normal-Medulla Wilms N9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal-Medulla Wilms Endothelium/Kidney Normal-Medulla Wilms N9 Adult, Development, and Cancer types 3.665E-4 2.086E-2
1.513E-1
2.910E-1
 1 1
14 GSM854271 100 Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2 Immgen.org, GSE15907 3.753E-4 2.086E-2
1.513E-1
2.980E-1
 2 81
15 GSM538282 100 Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3 Immgen.org, GSE15907 3.941E-4 2.086E-2
1.513E-1
3.129E-1
 2 83
16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour PapRCC R U/Kidney Tumour PapRCC R6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour PapRCC R U/Kidney Tumour PapRCC R6 Adult, Development, and Cancer types 4.632E-4 2.298E-2
1.668E-1
3.678E-1
 2 90
17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Tumour PapRCC Endothelium/Kidney Tumour PapRCC T2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Tumour PapRCC Endothelium/Kidney Tumour PapRCC T2 Adult, Development, and Cancer types 4.945E-4 2.309E-2
1.675E-1
3.926E-1
 2 93
18 gudmap developingKidney e13.5 podocyte cells 500 k2 DevelopingKidney e13.5 podocyte cells emap-27773 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 5.378E-4 2.372E-2
1.721E-1
4.270E-1
 2 97
19 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Tumour RCC Nephron epithelium/Kidney Tumour RCC N12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Tumour RCC Nephron epithelium/Kidney Tumour RCC N12 Adult, Development, and Cancer types 7.329E-4 2.569E-2
1.864E-1
5.819E-1
 1 2
20 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Private/Kidney Tumour VHL RCC Private/Kidney Tumour VHL RCC IN12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Private/Kidney Tumour VHL RCC Private/Kidney Tumour VHL RCC IN12 Adult, Development, and Cancer types 7.329E-4 2.569E-2
1.864E-1
5.819E-1
 1 2
21 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Normal-Medulla Wilms Nephrogenesis/Kidney Normal-Medulla Wilms F4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Normal-Medulla Wilms Nephrogenesis/Kidney Normal-Medulla Wilms F4 Adult, Development, and Cancer types 7.329E-4 2.569E-2
1.864E-1
5.819E-1
 1 2
22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Tumour VHL RCC Fetus other/Kidney Tumour VHL RCC F12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Tumour VHL RCC Fetus other/Kidney Tumour VHL RCC F12 Adult, Development, and Cancer types 1.099E-3 2.569E-2
1.864E-1
8.727E-1
 1 3
23 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Nonmucinous Lepidic Adenocarcinoma/5/3 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Nonmucinous Lepidic Adenocarcinoma/5/3 TCGA-Lung 1.261E-3 2.569E-2
1.864E-1
1.000E0
 2 149
24 Sample Type by Project: Shred 1/TCGA-Thymus/Thymoma/Type AB/1/3 Sample Type by Project: Shred 1/TCGA-Thymus/Thymoma/Type AB/1/3 TCGA-Thymus 1.381E-3 2.569E-2
1.864E-1
1.000E0
 2 156
25 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Overall Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Overall Top 200 Genes 1.399E-3 2.569E-2
1.864E-1
1.000E0
 2 157
26 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Micropapillary Adenocarcinoma/2 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Micropapillary Adenocarcinoma/2 TCGA-Lung 1.399E-3 2.569E-2
1.864E-1
1.000E0
 2 157
27 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour Wilms EN-A/Kidney Tumour Wilms EN0 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Tumour Wilms EN-A/Kidney Tumour Wilms EN0 Adult, Development, and Cancer types 1.465E-3 2.569E-2
1.864E-1
1.000E0
 1 4
28 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Tumour RCC Fetus other/Kidney Tumour RCC F12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Tumour RCC Fetus other/Kidney Tumour RCC F12 Adult, Development, and Cancer types 1.465E-3 2.569E-2
1.864E-1
1.000E0
 1 4
29 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Overall Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Overall Top 200 Genes 1.507E-3 2.569E-2
1.864E-1
1.000E0
 2 163
30 gudmap developingKidney e13.5 podocyte cells 1000 k5 DevelopingKidney e13.5 podocyte cells emap-27773 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.525E-3 2.569E-2
1.864E-1
1.000E0
 2 164
31 Lungmap Lungmap - Mouse FluidigmC1 Epithelial Epithelial Overall Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Epithelial Epithelial Overall Top 200 Genes 1.714E-3 2.569E-2
1.864E-1
1.000E0
 2 174
32 Mouse Lung Development Lungmap Mouse Fluidigm Epithelial Overall Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Epithelial Overall Top 200 Genes 1.773E-3 2.569E-2
1.864E-1
1.000E0
 2 177
33 10X Human 8K PBMC CD8 T cells (CCL5, NKG7, GZMK) Overall Top 200 Genes 10X Human 8K PBMC CD8 T cells (CCL5, NKG7, GZMK) Overall Top 200 Genes 1.813E-3 2.569E-2
1.864E-1
1.000E0
 2 179
34 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Private/Kidney Tumour RCC Private/Kidney Tumour RCC IN12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Private/Kidney Tumour RCC Private/Kidney Tumour RCC IN12 Adult, Development, and Cancer types 1.831E-3 2.569E-2
1.864E-1
1.000E0
 1 5
35 Sample Type by Project: Shred 1/TCGA-Breast/Breast Carcinoma/Infiltrating Lobular Carcinoma/1/3 Sample Type by Project: Shred 1/TCGA-Breast/Breast Carcinoma/Infiltrating Lobular Carcinoma/1/3 TCGA-Breast 1.831E-3 2.569E-2
1.864E-1
1.000E0
 1 5
36 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney CD8 T cell/Kidney Tumour VHL RCC CD8 T cell/Kidney Tumour VHL RCC IN10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney CD8 T cell/Kidney Tumour VHL RCC CD8 T cell/Kidney Tumour VHL RCC IN10 Adult, Development, and Cancer types 1.831E-3 2.569E-2
1.864E-1
1.000E0
 1 5
37 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Tumour PapRCC Nephrogenesis/Kidney Tumour PapRCC F10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney Tumour PapRCC Nephrogenesis/Kidney Tumour PapRCC F10 Adult, Development, and Cancer types 1.831E-3 2.569E-2
1.864E-1
1.000E0
 1 5
38 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour Wilms PT-U/Kidney Tumour Wilms PT0 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour Wilms PT-U/Kidney Tumour Wilms PT0 Adult, Development, and Cancer types 1.831E-3 2.569E-2
1.864E-1
1.000E0
 1 5
39 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R12 Adult, Development, and Cancer types 1.831E-3 2.569E-2
1.864E-1
1.000E0
 1 5
40 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/epithelial cell of lung Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/epithelial cell of lung Tabula Muris Consortium 1.893E-3 2.569E-2
1.864E-1
1.000E0
 2 183
41 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Kidney/macrophage Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Kidney/macrophage Tabula Muris Consortium 1.914E-3 2.569E-2
1.864E-1
1.000E0
 2 184
42 10X Human 8K PBMC CD8 T cell Overall Top 200 Genes 10X Human 8K PBMC CD8 T cell Overall Top 200 Genes 1.934E-3 2.569E-2
1.864E-1
1.000E0
 2 185
43 10X Human 8K PBMC CD8 T cells Overall Top 200 Genes 10X Human 8K PBMC CD8 T cells Overall Top 200 Genes 1.934E-3 2.569E-2
1.864E-1
1.000E0
 2 185
44 10X Human 8K PBMC CD4 T cells (IL7R, CD3D, CD3E) Overall Top 200 Genes 10X Human 8K PBMC CD4 T cells (IL7R, CD3D, CD3E) Overall Top 200 Genes 1.976E-3 2.569E-2
1.864E-1
1.000E0
 2 187
45 10X Human 8K PBMC CD4 T cells (CCL5, NKG7, GZMK) Overall Top 200 Genes 10X Human 8K PBMC CD4 T cells (CCL5, NKG7, GZMK) Overall Top 200 Genes 2.018E-3 2.569E-2
1.864E-1
1.000E0
 2 189
46 Human Cell Atlas Human Cell Atlas T cell T cell Overall Top 200 Genes Human Cell Atlas Human Cell Atlas T cell T cell Overall Top 200 Genes 2.039E-3 2.569E-2
1.864E-1
1.000E0
 2 190
47 10X Human 8K PBMC T cell Overall Top 200 Genes 10X Human 8K PBMC T cell Overall Top 200 Genes 2.039E-3 2.569E-2
1.864E-1
1.000E0
 2 190
48 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Tumour Wilms EN-B/Kidney Tumour Wilms EN9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Tumour Wilms EN-B/Kidney Tumour Wilms EN9 Adult, Development, and Cancer types 2.060E-3 2.569E-2
1.864E-1
1.000E0
 2 191
49 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Mucinous Rectal Adenocarcinoma/5/1 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Mucinous Rectal Adenocarcinoma/5/1 TCGA-Colorectal 2.060E-3 2.569E-2
1.864E-1
1.000E0
 2 191
50 Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Myeloid Myeloid Subtype macrophage-B PND07-28 Top 200 Genes 2.060E-3 2.569E-2
1.864E-1
1.000E0
 2 191
Show 45 more annotations

15: Computational [Display Chart] 6 input genes in category / 33 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M13673 MODULE 410 Cell adhesion. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.859E-4 3.242E-3 1.326E-2 6.136E-3 2 36
2 M5123 MODULE 96 Genes in the cancer module 96. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.965E-4 3.242E-3 1.326E-2 6.485E-3 2 37

16: MicroRNA [Display Chart] 8 input genes in category / 170 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-4286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.236E-5 1.230E-2
7.031E-2
 1.230E-2 2 117
2 hsa-miR-1306:PITA hsa-miR-1306:PITA TOP PITA 2.544E-3 3.617E-2
2.068E-1
4.325E-1
 1 23
3 hsa-miR-184:PITA hsa-miR-184:PITA TOP PITA 2.986E-3 3.617E-2
2.068E-1
5.077E-1
 1 27
4 hsa-miR-1238:PITA hsa-miR-1238:PITA TOP PITA 3.428E-3 3.617E-2
2.068E-1
5.828E-1
 1 31
5 hsa-miR-6731-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.311E-3 3.617E-2
2.068E-1
7.329E-1
 1 39
6 hsa-miR-203b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.311E-3 3.617E-2
2.068E-1
7.329E-1
 1 39
7 hsa-miR-6718-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.311E-3 3.617E-2
2.068E-1
7.329E-1
 1 39
8 hsa-miR-1251-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.532E-3 3.617E-2
2.068E-1
7.704E-1
 1 41
9 hsa-miR-1287-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.532E-3 3.617E-2
2.068E-1
7.704E-1
 1 41
10 hsa-miR-451:PITA hsa-miR-451:PITA TOP PITA 4.862E-3 3.617E-2
2.068E-1
8.266E-1
 1 44
11 hsa-miR-6767-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.973E-3 3.617E-2
2.068E-1
8.454E-1
 1 45
12 hsa-miR-5684:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.193E-3 3.617E-2
2.068E-1
8.828E-1
 1 47
13 hsa-miR-4460:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.193E-3 3.617E-2
2.068E-1
8.828E-1
 1 47
14 hsa-miR-4259:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.744E-3 3.617E-2
2.068E-1
9.765E-1
 1 52
15 hsa-miR-3617-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.744E-3 3.617E-2
2.068E-1
9.765E-1
 1 52
16 hsa-miR-4473:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.185E-3 3.617E-2
2.068E-1
1.000E0
 1 56
17 hsa-miR-5581-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.185E-3 3.617E-2
2.068E-1
1.000E0
 1 56
18 hsa-miR-4509:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.295E-3 3.617E-2
2.068E-1
1.000E0
 1 57
19 hsa-miR-4536-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.405E-3 3.617E-2
2.068E-1
1.000E0
 1 58
20 hsa-miR-6741-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.736E-3 3.617E-2
2.068E-1
1.000E0
 1 61
21 hsa-miR-154-5p:Non-Functional MTI Non-Functional MTI miRTarbase 6.956E-3 3.617E-2
2.068E-1
1.000E0
 1 63
22 hsa-miR-1288:PITA hsa-miR-1288:PITA TOP PITA 7.176E-3 3.617E-2
2.068E-1
1.000E0
 1 65
23 hsa-miR-101-5p:Functional MTI Functional MTI miRTarbase 7.506E-3 3.617E-2
2.068E-1
1.000E0
 1 68
24 hsa-miR-4744:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.616E-3 3.617E-2
2.068E-1
1.000E0
 1 69
25 hsa-miR-876-3p:Functional MTI Functional MTI miRTarbase 7.726E-3 3.617E-2
2.068E-1
1.000E0
 1 70
26 hsa-miR-4682:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.166E-3 3.617E-2
2.068E-1
1.000E0
 1 74
27 hsa-miR-6769a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.496E-3 3.617E-2
2.068E-1
1.000E0
 1 77
28 hsa-miR-3943:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.606E-3 3.617E-2
2.068E-1
1.000E0
 1 78
29 hsa-miR-4323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.045E-3 3.617E-2
2.068E-1
1.000E0
 1 82
30 hsa-miR-323a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.045E-3 3.617E-2
2.068E-1
1.000E0
 1 82
31 hsa-miR-8071:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.594E-3 3.617E-2
2.068E-1
1.000E0
 1 87
32 hsa-miR-324-5p:PITA hsa-miR-324-5p:PITA TOP PITA 1.047E-2 3.617E-2
2.068E-1
1.000E0
 1 95
33 hsa-miR-8066:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.080E-2 3.617E-2
2.068E-1
1.000E0
 1 98
34 hsa-miR-4291:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.080E-2 3.617E-2
2.068E-1
1.000E0
 1 98
35 hsa-miR-3591-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.080E-2 3.617E-2
2.068E-1
1.000E0
 1 98
36 hsa-miR-4426:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.091E-2 3.617E-2
2.068E-1
1.000E0
 1 99
37 hsa-miR-617:PITA hsa-miR-617:PITA TOP PITA 1.091E-2 3.617E-2
2.068E-1
1.000E0
 1 99
38 hsa-miR-4662b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.091E-2 3.617E-2
2.068E-1
1.000E0
 1 99
39 hsa-miR-4647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.091E-2 3.617E-2
2.068E-1
1.000E0
 1 99
40 hsa-miR-4281:mirSVR highEffct hsa-miR-4281:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.102E-2 3.617E-2
2.068E-1
1.000E0
 1 100
41 hsa-miR-140-5p:Functional MTI Functional MTI miRTarbase 1.113E-2 3.617E-2
2.068E-1
1.000E0
 1 101
42 hsa-miR-345:PITA hsa-miR-345:PITA TOP PITA 1.124E-2 3.617E-2
2.068E-1
1.000E0
 1 102
43 hsa-miR-4671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.124E-2 3.617E-2
2.068E-1
1.000E0
 1 102
44 hsa-miR-6777-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.135E-2 3.617E-2
2.068E-1
1.000E0
 1 103
45 hsa-miR-587:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.157E-2 3.617E-2
2.068E-1
1.000E0
 1 105
46 hsa-miR-1224-3p:PITA hsa-miR-1224-3p:PITA TOP PITA 1.168E-2 3.617E-2
2.068E-1
1.000E0
 1 106
47 hsa-miR-105-5p:Functional MTI Functional MTI miRTarbase 1.179E-2 3.617E-2
2.068E-1
1.000E0
 1 107
48 hsa-miR-1245a:Functional MTI Functional MTI miRTarbase 1.256E-2 3.617E-2
2.068E-1
1.000E0
 1 114
49 hsa-miR-3688-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.267E-2 3.617E-2
2.068E-1
1.000E0
 1 115
50 hsa-miR-1269:PITA hsa-miR-1269:PITA TOP PITA 1.277E-2 3.617E-2
2.068E-1
1.000E0
 1 116
Show 45 more annotations

17: Drug [Display Chart] 8 input genes in category / 1426 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000446641 indole-3-acetyl-l-valine Stitch 1.219E-6 1.739E-3 1.363E-2 1.739E-3 3 65
2 CID000008042 isopropyl myristate Stitch 1.830E-5 9.334E-3
7.318E-2
 2.610E-2 2 19
3 CID005287998 cu m Stitch 2.471E-5 9.334E-3
7.318E-2
 3.524E-2 2 22
4 CID000020138 butenal Stitch 2.618E-5 9.334E-3
7.318E-2
 3.733E-2 3 180
5 4091 UP Tiaprofenic acid [33005-95-7]; Up 200; 15.4uM; PC3; HT HG-U133A Broad Institute CMAP Up 3.586E-5 1.023E-2
8.018E-2
5.113E-2
 3 200
6 ctd:C117342 calfactant CTD 1.252E-4 2.081E-2
1.632E-1
1.785E-1
 2 49
7 CID000349960 Sialic acids Stitch 1.572E-4 2.081E-2
1.632E-1
2.241E-1
 3 329
8 CID000439306 AC1L973H Stitch 1.697E-4 2.081E-2
1.632E-1
2.420E-1
 2 57
9 CID000000897 H S Q Stitch 1.903E-4 2.081E-2
1.632E-1
2.713E-1
 3 351
10 CID000000840 rhamnose Stitch 1.984E-4 2.081E-2
1.632E-1
2.829E-1
 3 356
11 ctd:D010713 Phosphatidylcholines CTD 2.074E-4 2.081E-2
1.632E-1
2.958E-1
 2 63
12 CID000000294 maltos Stitch 2.655E-4 2.081E-2
1.632E-1
3.786E-1
 3 393
13 CID000006138 dipalmitoyl lecithin Stitch 2.863E-4 2.081E-2
1.632E-1
4.083E-1
 2 74
14 ctd:D001761 Bleomycin CTD 3.296E-4 2.081E-2
1.632E-1
4.699E-1
 3 423
15 ctd:C112292 rhodocytin protein, Calloselasma rhodostoma CTD 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
16 ctd:C025971 staphylococcal delta toxin CTD 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
17 CID000133622 1,4-butanediol diisethionate Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
18 CID000006924 toluenesulfonamide Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
19 CID000164027 1,4-bfs Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
20 CID005287447 1 DM Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
21 CID000062285 CS 1135 Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
22 DB00045 OspA lipoprotein Drug Bank 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
23 CID000069436 2-sulfamoylbenzoate Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
24 CID000075979 Preventol D2 Stitch 3.502E-4 2.081E-2
1.632E-1
4.995E-1
 1 1
25 CID000000899 N-acetylhexosamine Stitch 4.545E-4 2.592E-2
2.032E-1
6.481E-1
 3 472
26 CID000001029 hydroxylysine Stitch 6.201E-4 2.799E-2
2.194E-1
8.842E-1
 2 109
27 CID009989023 Pam2CSK4 Stitch 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
28 CID000010737 U973 Stitch 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
29 ctd:C038293 2,3-bis(palmitoyloxy)-2-propyl-N-palmitoyl-cysteinyl-seryl-seryl-asparaginyl-alanine CTD 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
30 CID000022947 DMDMH Stitch 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
31 CID000104556 1,3,5-trihydroxyethylhexahydrotriazine Stitch 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
32 CID000149947 AC1L3ZYH Stitch 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
33 ctd:D011663 Pulmonary Surfactants CTD 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
34 CID005327013 P1-D Stitch 7.004E-4 2.799E-2
2.194E-1
9.988E-1
 1 2
35 ctd:C472349 oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine CTD 1.034E-3 2.799E-2
2.194E-1
1.000E0
 2 141
36 ctd:D000069450 Liraglutide CTD 1.050E-3 2.799E-2
2.194E-1
1.000E0
 1 3
37 CID000066663 t964 Stitch 1.050E-3 2.799E-2
2.194E-1
1.000E0
 1 3
38 CID000061948 MDBGN Stitch 1.050E-3 2.799E-2
2.194E-1
1.000E0
 1 3
39 CID000129510 27-hydroxyoctacosanoic acid Stitch 1.050E-3 2.799E-2
2.194E-1
1.000E0
 1 3
40 CID000573621 3-maleimidopropionate Stitch 1.050E-3 2.799E-2
2.194E-1
1.000E0
 1 3
41 ctd:C490727 T 91825 CTD 1.050E-3 2.799E-2
2.194E-1
1.000E0
 1 3
42 CID000024823 ozone Stitch 1.063E-3 2.799E-2
2.194E-1
1.000E0
 2 143
43 ctd:C433788 lipopolysaccharide, E. coli O26-B6 CTD 1.093E-3 2.799E-2
2.194E-1
1.000E0
 2 145
44 6133 DN Verteporfin [129497-78-5]; Down 200; 2.8uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.328E-3 2.799E-2
2.194E-1
1.000E0
 2 160
45 CID000152469 glycerylcysteine Stitch 1.400E-3 2.799E-2
2.194E-1
1.000E0
 1 4
46 ctd:C005830 tributyrin CTD 1.400E-3 2.799E-2
2.194E-1
1.000E0
 1 4
47 CID006537503 AC1O6WXE Stitch 1.400E-3 2.799E-2
2.194E-1
1.000E0
 1 4
48 ctd:D012566 Sizofiran CTD 1.400E-3 2.799E-2
2.194E-1
1.000E0
 1 4
49 ctd:C482777 triazacyclononane CTD 1.400E-3 2.799E-2
2.194E-1
1.000E0
 1 4
50 CID000002090 alexidine Stitch 1.400E-3 2.799E-2
2.194E-1
1.000E0
 1 4
Show 45 more annotations

18: Disease [Display Chart] 8 input genes in category / 383 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0025303 Meningococcal Infections DisGeNET Curated 5.118E-9 1.960E-6 1.279E-5 1.960E-6 4 49
2 C0729531 Viral respiratory infection DisGeNET BeFree 2.253E-8 3.158E-6 2.061E-5 8.630E-6 3 13
3 C0042029 Urinary tract infection DisGeNET Curated 2.474E-8 3.158E-6 2.061E-5 9.475E-6 4 72
4 C0876973 Infectious disease of lung DisGeNET Curated 1.057E-7 1.012E-5 6.603E-5 4.047E-5 4 103
5 C0035235 Respiratory Syncytial Virus Infections DisGeNET Curated 1.536E-7 1.176E-5 7.677E-5 5.882E-5 4 113
6 C0025295 Meningitis, Pneumococcal DisGeNET BeFree 2.042E-7 1.304E-5 8.509E-5 7.822E-5 3 26
7 C0010043 Corneal Ulcer DisGeNET Curated 2.572E-7 1.407E-5 9.185E-5 9.851E-5 3 28
8 C1541923 Infective endocarditis DisGeNET BeFree 5.131E-7 2.301E-5 1.502E-4 1.965E-4 3 35
9 C1320214 Invasive Streptococcus pneumoniae disease DisGeNET BeFree 5.596E-7 2.301E-5 1.502E-4 2.143E-4 3 36
10 C0014121 Bacterial Endocarditis DisGeNET Curated 6.088E-7 2.301E-5 1.502E-4 2.332E-4 3 37
11 C0852283 Respiratory Distress Syndrome DisGeNET Curated 6.608E-7 2.301E-5 1.502E-4 2.531E-4 3 38
12 C1855179 CATARACT, ANTERIOR POLAR DisGeNET Curated 9.656E-7 2.998E-5 1.957E-4 3.698E-4 3 43
13 C0006287 Bronchopulmonary Dysplasia DisGeNET Curated 1.018E-6 2.998E-5 1.957E-4 3.898E-4 4 181
14 C0006271 Bronchiolitis DisGeNET Curated 1.936E-6 5.101E-5 3.329E-4 7.414E-4 3 54
15 C2931829 RDS - infants DisGeNET BeFree 2.131E-6 5.101E-5 3.329E-4 8.162E-4 2 5
16 cv:C1800706 Idiopathic fibrosing alveolitis, chronic form Clinical Variations 2.131E-6 5.101E-5 3.329E-4 8.162E-4 2 5
17 C0035220 Respiratory Distress Syndrome, Newborn DisGeNET Curated 2.282E-6 5.141E-5 3.355E-4 8.740E-4 3 57
18 C2350344 Chronic Lung Injury DisGeNET BeFree 3.196E-6 6.749E-5 4.405E-4 1.224E-3 2 6
19 C0375023 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site DisGeNET BeFree 3.348E-6 6.749E-5 4.405E-4 1.282E-3 4 244
20 OMIN:178500 PULMONARY FIBROSIS, IDIOPATHIC OMIM 4.473E-6 8.566E-5 5.591E-4 1.713E-3 2 7
21 C0035204 Respiration Disorders DisGeNET Curated 5.244E-6 9.565E-5 6.242E-4 2.009E-3 3 75
22 C0004610 Bacteremia DisGeNET Curated 8.209E-6 1.429E-4 9.327E-4 3.144E-3 3 87
23 C0264936 Secondary pulmonary hypertension DisGeNET BeFree 1.170E-5 1.875E-4 1.224E-3 4.482E-3 2 11
24 C0022876 Premature Obstetric Labor DisGeNET Curated 1.175E-5 1.875E-4 1.224E-3 4.500E-3 3 98
25 C0024115 Lung diseases DisGeNET Curated 1.382E-5 2.036E-4 1.329E-3 5.295E-3 4 349
26 C1800706 Idiopathic Pulmonary Fibrosis DisGeNET Curated 1.382E-5 2.036E-4 1.329E-3 5.295E-3 4 349
27 C0149778 Soft Tissue Infections DisGeNET BeFree 1.935E-5 2.745E-4 1.791E-3 7.411E-3 2 14
28 C0206062 Lung Diseases, Interstitial DisGeNET Curated 2.158E-5 2.952E-4 1.927E-3 8.267E-3 3 120
29 C0038160 Staphylococcal Infections DisGeNET Curated 2.890E-5 3.816E-4 2.491E-3 1.107E-2 2 17
30 C0032285 Pneumonia DisGeNET Curated 4.685E-5 5.981E-4 3.904E-3 1.794E-2 4 476
31 C0041327 Tuberculosis, Pulmonary DisGeNET Curated 5.007E-5 6.186E-4 4.037E-3 1.918E-2 3 159
32 C0004031 Aspergillosis, Allergic Bronchopulmonary DisGeNET BeFree 5.368E-5 6.424E-4 4.193E-3 2.056E-2 2 23
33 C0035222 Respiratory Distress Syndrome, Adult DisGeNET Curated 6.776E-5 7.762E-4 5.066E-3 2.595E-2 3 176
34 C2350236 Idiopathic Interstitial Pneumonias DisGeNET BeFree 6.890E-5 7.762E-4 5.066E-3 2.639E-2 2 26
35 C0600260 Lung Diseases, Obstructive DisGeNET Curated 7.439E-5 8.141E-4 5.313E-3 2.849E-2 2 27
36 C0034050 Pulmonary Alveolar Proteinosis DisGeNET Curated 1.050E-4 1.058E-3 6.907E-3 4.021E-2 2 32
37 C0340100 High altitude pulmonary edema DisGeNET Curated 1.050E-4 1.058E-3 6.907E-3 4.021E-2 2 32
38 C0238013 invasive aspergillosis DisGeNET BeFree 1.050E-4 1.058E-3 6.907E-3 4.021E-2 2 32
39 C3899278 Early Rheumatoid Arthritis DisGeNET BeFree 2.902E-4 2.850E-3 1.860E-2
1.111E-1
 2 53
40 C0035242 Respiratory Tract Diseases DisGeNET Curated 3.358E-4 3.215E-3 2.098E-2
1.286E-1
 2 57
41 C0280217 stage, non-small cell lung cancer DisGeNET BeFree 3.973E-4 3.567E-3 2.328E-2
1.522E-1
 2 62
42 C0026936 Mycoplasma Infections DisGeNET Curated 4.103E-4 3.567E-3 2.328E-2
1.571E-1
 2 63
43 C0020459 Hyperinsulinism DisGeNET Curated 4.229E-4 3.567E-3 2.328E-2
1.620E-1
 3 327
44 C0013371 Shigella Infections DisGeNET BeFree 4.503E-4 3.567E-3 2.328E-2
1.725E-1
 2 66
45 C0877046 Infection of tooth DisGeNET BeFree 4.937E-4 3.567E-3 2.328E-2
1.891E-1
 1 1
46 C0034535 Radiation Syndrome DisGeNET BeFree 4.937E-4 3.567E-3 2.328E-2
1.891E-1
 1 1
47 C3873302 Secondary pulmonary alveolar proteinosis DisGeNET BeFree 4.937E-4 3.567E-3 2.328E-2
1.891E-1
 1 1
48 C0040524 Septic Toxemia DisGeNET BeFree 4.937E-4 3.567E-3 2.328E-2
1.891E-1
 1 1
49 C0400837 Simple diverticular disease DisGeNET BeFree 4.937E-4 3.567E-3 2.328E-2
1.891E-1
 1 1
50 cv:C1968668 Leprosy 3 Clinical Variations 4.937E-4 3.567E-3 2.328E-2
1.891E-1
 1 1
Show 45 more annotations