Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc111_30, positive side

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1: GO: Molecular Function [Display Chart] 30 input genes in category / 108 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0045294 alpha-catenin binding 3.470E-12 3.747E-10 1.973E-9 3.747E-10 5 11
2 GO:0050839 cell adhesion molecule binding 9.873E-10 5.318E-8 2.800E-7 1.066E-7 8 208
3 GO:0045296 cadherin binding 1.477E-9 5.318E-8 2.800E-7 1.596E-7 5 32
4 GO:0045295 gamma-catenin binding 3.840E-9 1.037E-7 5.458E-7 4.148E-7 4 13
5 GO:0008013 beta-catenin binding 5.372E-9 1.160E-7 6.108E-7 5.802E-7 6 89
6 GO:0019903 protein phosphatase binding 8.919E-8 1.606E-6 8.451E-6 9.633E-6 6 142
7 GO:0019902 phosphatase binding 4.543E-7 7.009E-6 3.689E-5 4.906E-5 6 187
8 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity 2.511E-6 3.390E-5 1.784E-4 2.712E-4 3 17
9 GO:0019198 transmembrane receptor protein phosphatase activity 3.558E-5 4.031E-4 2.122E-3 3.843E-3 3 40
10 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication 3.733E-5 4.031E-4 2.122E-3 4.031E-3 2 6
11 GO:0086080 protein binding involved in heterotypic cell-cell adhesion 1.115E-4 1.095E-3 5.764E-3 1.205E-2 2 10
12 GO:0098632 cell-cell adhesion mediator activity 1.633E-4 1.469E-3 7.734E-3 1.763E-2 2 12
13 GO:0098631 cell adhesion mediator activity 3.762E-4 3.125E-3 1.645E-2 4.063E-2 2 18
14 GO:0050998 nitric-oxide synthase binding 5.657E-4 4.283E-3 2.255E-2
6.110E-2
 2 22
15 GO:0004725 protein tyrosine phosphatase activity 5.949E-4 4.283E-3 2.255E-2
6.425E-2
 3 103
16 GO:0044325 ion channel binding 1.093E-3 7.376E-3 3.883E-2
1.180E-1
 3 127
17 GO:0036479 peroxidase inhibitor activity 1.608E-3 9.646E-3
5.078E-2
1.736E-1
 1 1
18 GO:0005199 structural constituent of cell wall 1.608E-3 9.646E-3
5.078E-2
1.736E-1
 1 1
19 GO:1904713 beta-catenin destruction complex binding 3.213E-3 1.826E-2
9.613E-2
3.470E-1
 1 2
20 GO:0004721 phosphoprotein phosphatase activity 3.548E-3 1.916E-2
1.009E-1
3.832E-1
 3 192
21 GO:0070491 repressing transcription factor binding 4.173E-3 2.146E-2
1.130E-1
4.507E-1
 2 60
22 GO:0070698 type I activin receptor binding 4.815E-3 2.167E-2
1.141E-1
5.201E-1
 1 3
23 GO:0035373 chondroitin sulfate proteoglycan binding 4.815E-3 2.167E-2
1.141E-1
5.201E-1
 1 3
24 GO:1990188 euchromatin binding 4.815E-3 2.167E-2
1.141E-1
5.201E-1
 1 3
25 GO:0001618 virus receptor activity 5.796E-3 2.504E-2
1.318E-1
6.259E-1
 2 71
26 GO:1990226 histone methyltransferase binding 8.013E-3 3.329E-2
1.752E-1
8.654E-1
 1 5
27 GO:0017048 Rho GTPase binding 8.587E-3 3.435E-2
1.808E-1
9.274E-1
 2 87
28 GO:0016791 phosphatase activity 1.025E-2 3.955E-2
2.082E-1
1.000E0
 3 282
29 GO:0016015 morphogen activity 1.279E-2 4.317E-2
2.272E-1
1.000E0
 1 8
30 GO:0070697 activin receptor binding 1.279E-2 4.317E-2
2.272E-1
1.000E0
 1 8
31 GO:0034211 GTP-dependent protein kinase activity 1.279E-2 4.317E-2
2.272E-1
1.000E0
 1 8
32 GO:0097493 structural molecule activity conferring elasticity 1.279E-2 4.317E-2
2.272E-1
1.000E0
 1 8
33 GO:0001085 RNA polymerase II transcription factor binding 1.537E-2 4.926E-2
2.593E-1
1.000E0
 2 118
34 GO:0039706 co-receptor binding 1.596E-2 4.926E-2
2.593E-1
1.000E0
 1 10
35 GO:0002162 dystroglycan binding 1.596E-2 4.926E-2
2.593E-1
1.000E0
 1 10
Show 30 more annotations

2: GO: Biological Process [Display Chart] 30 input genes in category / 1600 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0045216 cell-cell junction organization 1.100E-17 1.761E-14 1.401E-13 1.761E-14 13 230
2 GO:0034330 cell junction organization 4.969E-17 3.975E-14 3.162E-13 7.950E-14 13 258
3 GO:0034332 adherens junction organization 2.472E-15 1.318E-12 1.049E-11 3.955E-12 10 121
4 GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules 3.566E-14 1.368E-11 1.089E-10 5.706E-11 11 230
5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules 4.276E-14 1.368E-11 1.089E-10 6.841E-11 10 160
6 GO:0034329 cell junction assembly 7.351E-10 1.960E-7 1.559E-6 1.176E-6 8 200
7 GO:0016055 Wnt signaling pathway 2.940E-9 6.719E-7 5.345E-6 4.703E-6 10 494
8 GO:0007043 cell-cell junction assembly 8.078E-9 1.616E-6 1.285E-5 1.292E-5 6 95
9 GO:0043588 skin development 9.818E-9 1.745E-6 1.389E-5 1.571E-5 8 278
10 GO:0060070 canonical Wnt signaling pathway 2.181E-8 3.489E-6 2.776E-5 3.489E-5 8 308
11 GO:0071681 cellular response to indole-3-methanol 3.764E-8 5.019E-6 3.993E-5 6.022E-5 3 5
12 GO:0071680 response to indole-3-methanol 3.764E-8 5.019E-6 3.993E-5 6.022E-5 3 5
13 GO:0008544 epidermis development 4.688E-8 5.770E-6 4.590E-5 7.501E-5 8 340
14 GO:0022404 molting cycle process 4.917E-7 4.917E-5 3.912E-4 7.867E-4 5 99
15 GO:0001942 hair follicle development 4.917E-7 4.917E-5 3.912E-4 7.867E-4 5 99
16 GO:0022405 hair cycle process 4.917E-7 4.917E-5 3.912E-4 7.867E-4 5 99
17 GO:0098773 skin epidermis development 5.433E-7 5.114E-5 4.068E-4 8.693E-4 5 101
18 GO:0030111 regulation of Wnt signaling pathway 6.261E-7 5.566E-5 4.428E-4 1.002E-3 7 322
19 GO:0042303 molting cycle 1.280E-6 9.882E-5 7.861E-4 2.048E-3 5 120
20 GO:0042633 hair cycle 1.280E-6 9.882E-5 7.861E-4 2.048E-3 5 120
21 GO:0034394 protein localization to cell surface 1.297E-6 9.882E-5 7.861E-4 2.075E-3 4 51
22 GO:0060828 regulation of canonical Wnt signaling pathway 2.170E-6 1.520E-4 1.209E-3 3.472E-3 6 244
23 GO:0043297 apical junction assembly 2.185E-6 1.520E-4 1.209E-3 3.496E-3 4 58
24 GO:0035148 tube formation 5.108E-6 3.405E-4 2.709E-3 8.173E-3 5 159
25 GO:0034333 adherens junction assembly 8.769E-6 5.612E-4 4.464E-3 1.403E-2 4 82
26 GO:0050678 regulation of epithelial cell proliferation 1.086E-5 6.683E-4 5.317E-3 1.738E-2 6 323
27 GO:0001708 cell fate specification 1.215E-5 7.197E-4 5.726E-3 1.943E-2 4 89
28 GO:0007369 gastrulation 1.278E-5 7.302E-4 5.809E-3 2.045E-2 5 192
29 GO:0060066 oviduct development 1.502E-5 8.288E-4 6.593E-3 2.403E-2 2 4
30 GO:0009913 epidermal cell differentiation 1.556E-5 8.301E-4 6.604E-3 2.490E-2 5 200
31 GO:0030178 negative regulation of Wnt signaling pathway 1.672E-5 8.632E-4 6.867E-3 2.676E-2 5 203
32 GO:0001702 gastrulation with mouth forming second 1.992E-5 9.960E-4 7.924E-3 3.187E-2 3 33
33 GO:0003002 regionalization 2.342E-5 1.090E-3 8.672E-3 3.748E-2 6 370
34 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules 2.384E-5 1.090E-3 8.672E-3 3.815E-2 3 35
35 GO:0009954 proximal/distal pattern formation 2.384E-5 1.090E-3 8.672E-3 3.815E-2 3 35
36 GO:0050673 epithelial cell proliferation 3.194E-5 1.419E-3 1.129E-2
5.110E-2
 6 391
37 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process 3.748E-5 1.578E-3 1.255E-2
5.997E-2
 2 6
38 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication 3.748E-5 1.578E-3 1.255E-2
5.997E-2
 2 6
39 GO:0045995 regulation of embryonic development 4.348E-5 1.784E-3 1.419E-2
6.956E-2
 4 123
40 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion 5.242E-5 2.097E-3 1.668E-2
8.387E-2
 2 7
41 GO:0051648 vesicle localization 6.200E-5 2.420E-3 1.925E-2
9.920E-2
 5 267
42 GO:0070830 bicellular tight junction assembly 7.025E-5 2.676E-3 2.129E-2
1.124E-1
 3 50
43 GO:0030856 regulation of epithelial cell differentiation 7.203E-5 2.680E-3 2.132E-2
1.152E-1
 4 140
44 GO:0097479 synaptic vesicle localization 7.405E-5 2.693E-3 2.142E-2
1.185E-1
 4 141
45 GO:0001838 embryonic epithelial tube formation 7.821E-5 2.781E-3 2.212E-2
1.251E-1
 4 143
46 GO:0072175 epithelial tube formation 8.036E-5 2.795E-3 2.224E-2
1.286E-1
 4 144
47 GO:2000241 regulation of reproductive process 8.937E-5 3.042E-3 2.420E-2
1.430E-1
 4 148
48 GO:0048568 embryonic organ development 9.856E-5 3.285E-3 2.614E-2
1.577E-1
 6 479
49 GO:0002065 columnar/cuboidal epithelial cell differentiation 1.016E-4 3.319E-3 2.640E-2
1.626E-1
 4 153
50 GO:2000242 negative regulation of reproductive process 1.096E-4 3.446E-3 2.741E-2
1.754E-1
 3 58
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 30 input genes in category / 163 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005911 cell-cell junction 2.364E-19 3.853E-17 2.186E-16 3.853E-17 16 418
2 GO:0005913 cell-cell adherens junction 4.748E-18 3.870E-16 2.196E-15 7.740E-16 10 68
3 GO:0005912 adherens junction 1.038E-16 5.641E-15 3.201E-14 1.692E-14 15 484
4 GO:0016342 catenin complex 8.531E-13 3.476E-11 1.972E-10 1.391E-10 5 9
5 GO:0043296 apical junction complex 2.067E-11 6.739E-10 3.824E-9 3.370E-9 8 131
6 GO:0044291 cell-cell contact zone 1.191E-9 3.236E-8 1.836E-7 1.941E-7 6 71
7 GO:0034750 Scrib-APC-beta-catenin complex 3.518E-9 7.190E-8 4.080E-7 5.735E-7 3 3
8 GO:0005916 fascia adherens 3.529E-9 7.190E-8 4.080E-7 5.752E-7 4 13
9 GO:0016328 lateral plasma membrane 1.852E-8 3.353E-7 1.903E-6 3.018E-6 5 53
10 GO:0014704 intercalated disc 2.940E-8 4.793E-7 2.719E-6 4.793E-6 5 58
11 GO:0030057 desmosome 7.274E-8 1.078E-6 6.116E-6 1.186E-5 4 26
12 GO:0005925 focal adhesion 1.197E-7 1.626E-6 9.224E-6 1.951E-5 8 393
13 GO:0005924 cell-substrate adherens junction 1.318E-7 1.653E-6 9.380E-6 2.149E-5 8 398
14 GO:0030055 cell-substrate junction 1.451E-7 1.689E-6 9.583E-6 2.365E-5 8 403
15 GO:0005915 zonula adherens 2.936E-7 3.191E-6 1.811E-5 4.786E-5 3 9
16 GO:0030027 lamellipodium 3.892E-7 3.965E-6 2.250E-5 6.344E-5 6 186
17 GO:0016600 flotillin complex 5.756E-7 5.330E-6 3.024E-5 9.382E-5 3 11
18 GO:0044853 plasma membrane raft 5.885E-7 5.330E-6 3.024E-5 9.593E-5 5 105
19 GO:0045121 membrane raft 8.195E-7 6.679E-6 3.789E-5 1.336E-4 7 343
20 GO:0098857 membrane microdomain 8.195E-7 6.679E-6 3.789E-5 1.336E-4 7 343
21 GO:0005923 bicellular tight junction 9.253E-7 7.182E-6 4.075E-5 1.508E-4 5 115
22 GO:0070160 tight junction 1.051E-6 7.789E-6 4.420E-5 1.714E-4 5 118
23 GO:1990909 Wnt signalosome 1.266E-6 8.970E-6 5.090E-5 2.063E-4 3 14
24 GO:0031252 cell leading edge 1.897E-6 1.288E-5 7.309E-5 3.091E-4 7 389
25 GO:0019897 extrinsic component of plasma membrane 3.663E-6 2.388E-5 1.355E-4 5.970E-4 5 152
26 GO:0071664 catenin-TCF7L2 complex 7.177E-6 4.499E-5 2.553E-4 1.170E-3 2 3
27 GO:0099568 cytoplasmic region 9.864E-6 5.955E-5 3.379E-4 1.608E-3 6 325
28 GO:0005901 caveola 1.497E-5 8.717E-5 4.946E-4 2.441E-3 4 96
29 GO:0005938 cell cortex 5.459E-5 3.068E-4 1.741E-3 8.898E-3 5 266
30 GO:0019898 extrinsic component of membrane 6.729E-5 3.656E-4 2.074E-3 1.097E-2 5 278
31 GO:0015629 actin cytoskeleton 8.382E-5 4.407E-4 2.501E-3 1.366E-2 6 476
32 GO:0030864 cortical actin cytoskeleton 1.646E-4 8.382E-4 4.756E-3 2.682E-2 3 68
33 GO:0030426 growth cone 1.815E-4 8.965E-4 5.087E-3 2.958E-2 4 182
34 GO:0030427 site of polarized growth 2.014E-4 9.653E-4 5.477E-3 3.282E-2 4 187
35 GO:0030877 beta-catenin destruction complex 2.154E-4 1.003E-3 5.691E-3 3.511E-2 2 14
36 GO:0044449 contractile fiber part 3.427E-4 1.552E-3 8.804E-3
5.586E-2
 4 215
37 GO:0030016 myofibril 3.739E-4 1.647E-3 9.346E-3
6.095E-2
 4 220
38 GO:0030863 cortical cytoskeleton 4.694E-4 1.973E-3 1.120E-2
7.652E-2
 3 97
39 GO:0043292 contractile fiber 4.721E-4 1.973E-3 1.120E-2
7.695E-2
 4 234
40 GO:0043034 costamere 4.936E-4 2.011E-3 1.141E-2
8.046E-2
 2 21
41 GO:0016323 basolateral plasma membrane 5.526E-4 2.197E-3 1.247E-2
9.008E-2
 4 244
42 GO:0030018 Z disc 8.517E-4 3.306E-3 1.876E-2
1.388E-1
 3 119
43 GO:0031674 I band 1.226E-3 4.649E-3 2.638E-2
1.999E-1
 3 135
44 GO:0044448 cell cortex part 1.306E-3 4.840E-3 2.746E-2
2.130E-1
 3 138
45 GO:0090636 outer dense plaque of desmosome 1.574E-3 5.345E-3 3.033E-2
2.565E-1
 1 1
46 GO:0090637 inner dense plaque of desmosome 1.574E-3 5.345E-3 3.033E-2
2.565E-1
 1 1
47 GO:0032473 cytoplasmic side of mitochondrial outer membrane 1.574E-3 5.345E-3 3.033E-2
2.565E-1
 1 1
48 GO:0071665 gamma-catenin-TCF7L2 complex 1.574E-3 5.345E-3 3.033E-2
2.565E-1
 1 1
49 GO:0042383 sarcolemma 1.724E-3 5.734E-3 3.253E-2
2.809E-1
 3 152
50 GO:0098562 cytoplasmic side of membrane 2.966E-3 9.669E-3
5.486E-2
4.834E-1
 3 184
Show 45 more annotations

4: Human Phenotype [Display Chart] 15 input genes in category / 1137 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0012126 Stomach cancer 6.517E-5 2.871E-2
2.186E-1
7.410E-2
 3 26
2 HP:0200040 Epidermoid cyst 8.180E-5 2.871E-2
2.186E-1
9.301E-2
 3 28
3 HP:0100245 Desmoid tumors 9.428E-5 2.871E-2
2.186E-1
1.072E-1
 2 5
4 HP:0025245 Cutaneous cyst 1.010E-4 2.871E-2
2.186E-1
1.148E-1
 3 30

5: Mouse Phenotype [Display Chart] 24 input genes in category / 1897 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0001695 abnormal gastrulation 1.150E-7 1.325E-4 1.076E-3 2.181E-4 9 392
2 MP:0000267 abnormal heart development 1.397E-7 1.325E-4 1.076E-3 2.649E-4 9 401
3 MP:0009685 abnormal spinal cord motor column morphology 3.806E-7 2.399E-4 1.949E-3 7.220E-4 3 7
4 MP:0001718 abnormal visceral yolk sac morphology 6.288E-7 2.399E-4 1.949E-3 1.193E-3 7 231
5 MP:0001700 abnormal embryo turning 7.477E-7 2.399E-4 1.949E-3 1.418E-3 7 237
6 MP:0001680 abnormal mesoderm development 7.587E-7 2.399E-4 1.949E-3 1.439E-3 5 77
7 MP:0001730 embryonic growth arrest 4.037E-6 1.094E-3 8.891E-3 7.659E-3 7 305
8 MP:0012087 absent midbrain 6.007E-6 1.143E-3 9.286E-3 1.139E-2 3 16
9 MP:0011523 thin placenta labyrinth 6.007E-6 1.143E-3 9.286E-3 1.139E-2 3 16
10 MP:0011521 decreased placental labyrinth size 6.024E-6 1.143E-3 9.286E-3 1.143E-2 4 53
11 MP:0011519 abnormal placenta labyrinth size 8.661E-6 1.494E-3 1.214E-2 1.643E-2 4 58
12 MP:0012082 delayed heart development 1.035E-5 1.510E-3 1.227E-2 1.963E-2 3 19
13 MP:0001341 absent eyelids 1.035E-5 1.510E-3 1.227E-2 1.963E-2 3 19
14 MP:0001711 abnormal placenta morphology 1.246E-5 1.641E-3 1.333E-2 2.363E-2 7 362
15 MP:0001688 abnormal somite development 1.482E-5 1.641E-3 1.333E-2 2.811E-2 6 243
16 MP:0002013 increased pilomatricoma incidence 1.542E-5 1.641E-3 1.333E-2 2.926E-2 2 3
17 MP:0009686 abnormal spinal cord medial motor column morphology 1.542E-5 1.641E-3 1.333E-2 2.926E-2 2 3
18 MP:0001674 abnormal germ layer development 1.557E-5 1.641E-3 1.333E-2 2.954E-2 5 142
19 MP:0009220 increased prostate gland adenocarcinoma incidence 1.879E-5 1.876E-3 1.525E-2 3.565E-2 3 23
20 MP:0003232 abnormal forebrain development 2.129E-5 1.956E-3 1.589E-2 4.039E-2 6 259
21 MP:0012501 abnormal pericardial cavity morphology 2.165E-5 1.956E-3 1.589E-2 4.107E-2 5 152
22 MP:0000628 abnormal mammary gland development 2.306E-5 1.988E-3 1.616E-2 4.375E-2 5 154
23 MP:0012176 abnormal head development 2.547E-5 2.101E-3 1.707E-2 4.832E-2 4 76
24 MP:0000288 abnormal pericardium morphology 2.694E-5 2.129E-3 1.730E-2
5.111E-2
 6 270
25 MP:0013754 abnormal ocular surface morphology 3.278E-5 2.281E-3 1.854E-2
6.218E-2
 4 81
26 MP:0012157 rostral body truncation 3.450E-5 2.281E-3 1.854E-2
6.545E-2
 3 28
27 MP:0006267 abnormal intercalated disk morphology 3.450E-5 2.281E-3 1.854E-2
6.545E-2
 3 28
28 MP:0000260 abnormal angiogenesis 3.521E-5 2.281E-3 1.854E-2
6.679E-2
 7 425
29 MP:0003566 abnormal cell adhesion 3.784E-5 2.281E-3 1.854E-2
7.177E-2
 4 84
30 MP:0009219 increased prostate intraepithelial neoplasia incidence 3.843E-5 2.281E-3 1.854E-2
7.289E-2
 3 29
31 MP:0001208 blistering 3.843E-5 2.281E-3 1.854E-2
7.289E-2
 3 29
32 MP:0030385 absent facial bone 3.964E-5 2.281E-3 1.854E-2
7.520E-2
 4 85
33 MP:0003935 abnormal craniofacial development 3.968E-5 2.281E-3 1.854E-2
7.528E-2
 7 433
34 MP:0000087 absent mandible 5.192E-5 2.897E-3 2.354E-2
9.850E-2
 3 32
35 MP:0003630 abnormal urothelium morphology 5.703E-5 3.091E-3 2.511E-2
1.082E-1
 3 33
36 MP:0000270 abnormal heart tube morphology 6.659E-5 3.509E-3 2.851E-2
1.263E-1
 4 97
37 MP:0003119 abnormal digestive system development 7.501E-5 3.735E-3 3.035E-2
1.423E-1
 4 100
38 MP:0009684 abnormal spinal cord lateral motor column morphology 7.679E-5 3.735E-3 3.035E-2
1.457E-1
 2 6
39 MP:0010313 increased osteoma incidence 7.679E-5 3.735E-3 3.035E-2
1.457E-1
 2 6
40 MP:0010357 increased prostate gland tumor incidence 8.072E-5 3.735E-3 3.035E-2
1.531E-1
 3 37
41 MP:0009506 abnormal mammary gland alveolus morphology 8.072E-5 3.735E-3 3.035E-2
1.531E-1
 3 37
42 MP:0000474 abnormal foregut morphology 8.751E-5 3.952E-3 3.212E-2
1.660E-1
 3 38
43 MP:0009505 abnormal mammary gland lobule morphology 1.022E-4 4.508E-3 3.663E-2
1.938E-1
 3 40
44 MP:0001726 abnormal allantois morphology 1.049E-4 4.525E-3 3.676E-2
1.991E-1
 4 109
45 MP:0001710 absent amniotic folds 1.074E-4 4.526E-3 3.677E-2
2.037E-1
 2 7
46 MP:0030268 agnathia 1.101E-4 4.533E-3 3.683E-2
2.088E-1
 3 41
47 MP:0001722 pale yolk sac 1.126E-4 4.533E-3 3.683E-2
2.137E-1
 4 111
48 MP:0001286 abnormal eye development 1.147E-4 4.533E-3 3.683E-2
2.176E-1
 6 350
49 MP:0013442 abnormal Harderian gland size 1.429E-4 5.448E-3 4.427E-2
2.712E-1
 2 8
50 MP:0002957 increased intestinal adenocarcinoma incidence 1.456E-4 5.448E-3 4.427E-2
2.763E-1
 3 45
Show 45 more annotations

6: Domain [Display Chart] 30 input genes in category / 207 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR020894 Cadherin CS InterPro 5.322E-12 2.613E-10 1.545E-9 1.102E-9 8 109
2 PS00232 CADHERIN 1 PROSITE 7.139E-12 2.613E-10 1.545E-9 1.478E-9 8 113
3 PF00028 Cadherin Pfam 7.139E-12 2.613E-10 1.545E-9 1.478E-9 8 113
4 PS50268 CADHERIN 2 PROSITE 7.669E-12 2.613E-10 1.545E-9 1.588E-9 8 114
5 2.60.40.60 - Gene3D 7.669E-12 2.613E-10 1.545E-9 1.588E-9 8 114
6 SM00112 CA SMART 8.234E-12 2.613E-10 1.545E-9 1.704E-9 8 115
7 IPR015919 Cadherin-like InterPro 8.835E-12 2.613E-10 1.545E-9 1.829E-9 8 116
8 IPR002126 Cadherin InterPro 1.015E-11 2.627E-10 1.553E-9 2.101E-9 8 118
9 PF01049 Cadherin C Pfam 3.852E-10 7.973E-9 4.714E-8 7.973E-8 5 25
10 IPR000233 Cadherin cytoplasmic-dom InterPro 3.852E-10 7.973E-9 4.714E-8 7.973E-8 5 25
11 IPR027397 Catenin binding dom InterPro 8.571E-10 1.478E-8 8.741E-8 1.774E-7 5 29
12 4.10.900.10 - Gene3D 8.571E-10 1.478E-8 8.741E-8 1.774E-7 5 29
13 PF00514 Arm Pfam 1.224E-9 1.948E-8 1.152E-7 2.533E-7 5 31
14 SM00185 ARM SMART 4.691E-9 6.474E-8 3.828E-7 9.711E-7 5 40
15 PS50176 ARM REPEAT PROSITE 4.691E-9 6.474E-8 3.828E-7 9.711E-7 5 40
16 IPR000225 Armadillo InterPro 1.085E-8 1.404E-7 8.300E-7 2.246E-6 5 47
17 SM01055 Cadherin pro SMART 2.064E-7 2.373E-6 1.403E-5 4.272E-5 3 8
18 IPR014868 Cadherin pro dom InterPro 2.064E-7 2.373E-6 1.403E-5 4.272E-5 3 8
19 1.25.10.10 - Gene3D 1.211E-6 1.320E-5 7.802E-5 2.507E-4 6 222
20 IPR013284 Beta-catenin InterPro 2.479E-6 2.566E-5 1.517E-4 5.131E-4 2 2
21 IPR011989 ARM-like InterPro 3.844E-6 3.789E-5 2.240E-4 7.957E-4 6 271
22 IPR016024 ARM-type fold InterPro 1.405E-5 1.322E-4 7.815E-4 2.908E-3 6 340
23 IPR013585 Protocadherin InterPro 2.471E-5 2.114E-4 1.250E-3 5.116E-3 2 5
24 PF08374 Protocadherin Pfam 2.471E-5 2.114E-4 1.250E-3 5.116E-3 2 5
25 SM00194 PTPc SMART 2.553E-5 2.114E-4 1.250E-3 5.284E-3 3 36
26 PS50055 TYR PHOSPHATASE PTP PROSITE 3.257E-5 2.593E-4 1.533E-3 6.741E-3 3 39
27 PF00102 Y phosphatase Pfam 3.791E-5 2.802E-4 1.657E-3 7.846E-3 3 41
28 IPR000242 PTPase domain InterPro 3.791E-5 2.802E-4 1.657E-3 7.846E-3 3 41
29 IPR028435 Plakophilin/d Catenin InterPro 5.180E-5 3.574E-4 2.113E-3 1.072E-2 2 7
30 PF08758 Cadherin pro Pfam 5.180E-5 3.574E-4 2.113E-3 1.072E-2 2 7
31 IPR003595 Tyr Pase cat InterPro 1.134E-4 7.334E-4 4.336E-3 2.347E-2 3 59
32 SM00404 PTPc motif SMART 1.134E-4 7.334E-4 4.336E-3 2.347E-2 3 59
33 IPR016130 Tyr Pase AS InterPro 2.136E-4 1.340E-3 7.923E-3 4.423E-2 3 73
34 PS00383 TYR PHOSPHATASE 1 PROSITE 3.466E-4 2.062E-3 1.219E-2
7.176E-2
 3 86
35 IPR000387 TYR PHOSPHATASE dom InterPro 3.586E-4 2.062E-3 1.219E-2
7.424E-2
 3 87
36 PS50056 TYR PHOSPHATASE 2 PROSITE 3.586E-4 2.062E-3 1.219E-2
7.424E-2
 3 87
37 3.90.190.10 - Gene3D 4.226E-4 2.364E-3 1.398E-2
8.748E-2
 3 92
38 IPR029021 Prot-tyrosine phosphatase-like InterPro 5.239E-4 2.854E-3 1.687E-2
1.084E-1
 3 99
39 PF12632 Vezatin Pfam 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
40 IPR030052 CDH5 InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
41 IPR030461 Plakoglobin/HMP-2 InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
42 PF06541 ABC trans CmpB Pfam 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
43 IPR030051 CDH2 InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
44 IPR026836 APC InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
45 IPR009232 EB1-bd InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
46 IPR028439 Catenin d1 InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
47 IPR010540 CmpB TMEM229 InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
48 PF05972 APC 15aa Pfam 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
49 IPR009240 APC 15aa rpt InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
50 IPR026859 Myosin-bd InterPro 1.601E-3 5.919E-3 3.500E-2
3.315E-1
 1 1
Show 45 more annotations

7: Pathway [Display Chart] 27 input genes in category / 223 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1270234 Adherens junctions interactions BioSystems: REACTOME 1.188E-15 2.650E-13 1.586E-12 2.650E-13 8 31
2 1270233 Cell-cell junction organization BioSystems: REACTOME 4.883E-13 5.444E-11 3.259E-10 1.089E-10 8 62
3 1270232 Cell junction organization BioSystems: REACTOME 9.831E-12 7.307E-10 4.375E-9 2.192E-9 8 89
4 P00012 Cadherin signaling pathway PantherDB 2.772E-11 1.545E-9 9.252E-9 6.182E-9 9 159
5 83070 Adherens junction BioSystems: KEGG 1.300E-10 5.797E-9 3.470E-8 2.898E-8 7 72
6 1270231 Cell-Cell communication BioSystems: REACTOME 2.727E-10 1.014E-8 6.069E-8 6.082E-8 8 134
7 P00057 Wnt signaling pathway PantherDB 8.986E-9 2.863E-7 1.714E-6 2.004E-6 9 305
8 1269484 VEGFR2 mediated vascular permeability BioSystems: REACTOME 4.015E-7 1.119E-5 6.699E-5 8.952E-5 4 29
9 83069 Cell adhesion molecules (CAMs) BioSystems: KEGG 5.444E-7 1.349E-5 8.075E-5 1.214E-4 6 145
10 138005 E-cadherin signaling in the nascent adherens junction BioSystems: Pathway Interaction Database 6.876E-7 1.533E-5 9.179E-5 1.533E-4 4 33
11 1470918 InlA-mediated entry of Listeria monocytogenes into host cells BioSystems: REACTOME 7.575E-7 1.536E-5 9.193E-5 1.689E-4 3 9
12 1270288 Apoptotic cleavage of cellular proteins BioSystems: REACTOME 1.370E-6 2.421E-5 1.449E-4 3.055E-4 4 39
13 1270290 Apoptotic cleavage of cell adhesion proteins BioSystems: REACTOME 1.484E-6 2.421E-5 1.449E-4 3.309E-4 3 11
14 137918 Stabilization and expansion of the E-cadherin adherens junction BioSystems: Pathway Interaction Database 1.520E-6 2.421E-5 1.449E-4 3.389E-4 4 40
15 137954 Arf6 trafficking events BioSystems: Pathway Interaction Database 2.244E-6 3.336E-5 1.997E-4 5.005E-4 4 44
16 137966 E-cadherin signaling events BioSystems: Pathway Interaction Database 4.529E-6 6.266E-5 3.751E-4 1.010E-3 2 2
17 1270287 Apoptotic execution phase BioSystems: REACTOME 4.777E-6 6.266E-5 3.751E-4 1.065E-3 4 53
18 1470917 Listeria monocytogenes entry into host cells BioSystems: REACTOME 1.012E-5 1.254E-4 7.504E-4 2.256E-3 3 20
19 117293 Arrhythmogenic right ventricular cardiomyopathy (ARVC) BioSystems: KEGG 1.632E-5 1.819E-4 1.089E-3 3.639E-3 4 72
20 137930 Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met) BioSystems: Pathway Interaction Database 1.632E-5 1.819E-4 1.089E-3 3.639E-3 4 72
21 138054 Nectin adhesion pathway BioSystems: Pathway Interaction Database 2.027E-5 2.152E-4 1.288E-3 4.519E-3 3 25
22 PW:0000599 altered canonical Wnt signaling Pathway Ontology 4.511E-5 4.573E-4 2.737E-3 1.006E-2 2 5
23 137919 N-cadherin signaling events BioSystems: Pathway Interaction Database 4.752E-5 4.608E-4 2.758E-3 1.060E-2 3 33
24 P00004 Alzheimer disease-presenilin pathway PantherDB 9.611E-5 8.872E-4 5.311E-3 2.143E-2 4 113
25 83083 Leukocyte transendothelial migration BioSystems: KEGG 9.946E-5 8.872E-4 5.311E-3 2.218E-2 4 114
26 137989 FGF signaling pathway BioSystems: Pathway Interaction Database 1.384E-4 1.187E-3 7.107E-3 3.086E-2 3 47
27 83109 Endometrial cancer BioSystems: KEGG 1.666E-4 1.376E-3 8.236E-3 3.715E-2 3 50
28 749777 Hippo signaling pathway BioSystems: KEGG 3.165E-4 2.502E-3 1.498E-2
7.059E-2
 4 154
29 137940 Signaling events mediated by VEGFR1 and VEGFR2 BioSystems: Pathway Interaction Database 3.312E-4 2.502E-3 1.498E-2
7.386E-2
 3 63
30 1269516 RHO GTPases activate IQGAPs BioSystems: REACTOME 3.481E-4 2.502E-3 1.498E-2
7.763E-2
 2 13
31 M12851 Cell to Cell Adhesion Signaling MSigDB C2 BIOCARTA (v6.0) 4.056E-4 2.502E-3 1.498E-2
9.045E-2
 2 14
32 M16173 Presenilin action in Notch and Wnt signaling MSigDB C2 BIOCARTA (v6.0) 4.056E-4 2.502E-3 1.498E-2
9.045E-2
 2 14
33 137994 CDC42 signaling events BioSystems: Pathway Interaction Database 4.520E-4 2.502E-3 1.498E-2
1.008E-1
 3 70
34 1268916 phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex BioSystems: REACTOME 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
35 M8516 Multi-step Regulation of Transcription by Pitx2 MSigDB C2 BIOCARTA (v6.0) 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
36 1268919 S37 mutants of beta-catenin aren't phosphorylated BioSystems: REACTOME 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
37 1268920 S33 mutants of beta-catenin aren't phosphorylated BioSystems: REACTOME 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
38 1268917 S45 mutants of beta-catenin aren't phosphorylated BioSystems: REACTOME 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
39 1268921 Misspliced GSK3beta mutants stabilize beta-catenin BioSystems: REACTOME 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
40 PW:0000200 the planar cell polarity Wnt signaling Pathway Ontology 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
41 1268918 T41 mutants of beta-catenin aren't phosphorylated BioSystems: REACTOME 4.674E-4 2.502E-3 1.498E-2
1.042E-1
 2 15
42 1457791 Formation of the cornified envelope BioSystems: REACTOME 4.712E-4 2.502E-3 1.498E-2
1.051E-1
 3 71
43 1270262 Apoptosis BioSystems: REACTOME 5.031E-4 2.609E-3 1.562E-2
1.122E-1
 4 174
44 1270261 Programmed Cell Death BioSystems: REACTOME 5.367E-4 2.720E-3 1.628E-2
1.197E-1
 4 177
45 149807 Bacterial invasion of epithelial cells BioSystems: KEGG 5.754E-4 2.852E-3 1.707E-2
1.283E-1
 3 76
46 1269597 Beta-catenin phosphorylation cascade BioSystems: REACTOME 6.037E-4 2.927E-3 1.752E-2
1.346E-1
 2 17
47 169352 Regulation of Wnt-mediated beta catenin signaling and target gene transcription BioSystems: Pathway Interaction Database 6.445E-4 3.058E-3 1.831E-2
1.437E-1
 3 79
48 1269483 VEGFA-VEGFR2 Pathway BioSystems: REACTOME 6.604E-4 3.068E-3 1.837E-2
1.473E-1
 5 333
49 PW:0000612 colorectal cancer Pathway Ontology 6.783E-4 3.087E-3 1.848E-2
1.513E-1
 2 18
50 1269480 Signaling by VEGF BioSystems: REACTOME 7.354E-4 3.185E-3 1.907E-2
1.640E-1
 5 341
Show 45 more annotations

8: Pubmed [Display Chart] 30 input genes in category / 13413 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 7806582 E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton. Pubmed 6.530E-21 8.759E-17 8.830E-16 8.759E-17 8 20
2 16973135 Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT). Pubmed 1.269E-16 8.511E-13 8.580E-12 1.702E-12 6 12
3 11712088 Expression and interaction of different catenins in colorectal carcinoma cells. Pubmed 2.105E-16 9.411E-13 9.487E-12 2.823E-12 5 5
4 15775979 E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. Pubmed 5.301E-15 1.422E-11 1.434E-10 7.110E-11 6 20
5 16887818 Disruption of early proximodistal patterning and AVE formation in Apc mutants. Pubmed 5.301E-15 1.422E-11 1.434E-10 7.110E-11 6 20
6 18809908 New insights into cadherin function in epidermal sheet formation and maintenance of tissue integrity. Pubmed 1.019E-14 1.754E-11 1.768E-10 1.367E-10 6 22
7 9535896 The epidermal growth factor receptor modulates the interaction of E-cadherin with the actin cytoskeleton. Pubmed 1.177E-14 1.754E-11 1.768E-10 1.578E-10 5 8
8 12112462 Regulation of cadherin junctions during mouse submandibular gland development. Pubmed 1.177E-14 1.754E-11 1.768E-10 1.578E-10 5 8
9 11821434 The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF. Pubmed 1.177E-14 1.754E-11 1.768E-10 1.578E-10 5 8
10 14625392 A novel cell-cell junction system: the cortex adhaerens mosaic of lens fiber cells. Pubmed 9.692E-14 1.182E-10 1.191E-9 1.300E-9 5 11
11 22479204 Igf1r signaling is indispensable for preimplantation development and is activated via a novel function of E-cadherin. Pubmed 9.692E-14 1.182E-10 1.191E-9 1.300E-9 5 11
12 28295003 [Epithelial cadherins and associated molecules in invasive lobular breast cancer]. Pubmed 3.092E-13 2.439E-10 2.459E-9 4.147E-9 4 4
13 11348595 The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin. Pubmed 3.092E-13 2.439E-10 2.459E-9 4.147E-9 4 4
14 23180380 P-cadherin functional role is dependent on E-cadherin cellular context: a proof of concept using the breast cancer model. Pubmed 3.092E-13 2.439E-10 2.459E-9 4.147E-9 4 4
15 7876318 Association of p120, a tyrosine kinase substrate, with E-cadherin/catenin complexes. Pubmed 3.092E-13 2.439E-10 2.459E-9 4.147E-9 4 4
16 8074697 Association of plakoglobin with APC, a tumor suppressor gene product, and its regulation by tyrosine phosphorylation. Pubmed 3.092E-13 2.439E-10 2.459E-9 4.147E-9 4 4
17 18837082 Reduced expression of E-cadherin/catenin complex in hepatocellular carcinomas. Pubmed 3.092E-13 2.439E-10 2.459E-9 4.147E-9 4 4
18 23108156 p63 control of desmosome gene expression and adhesion is compromised in AEC syndrome. Pubmed 6.286E-13 4.684E-10 4.722E-9 8.432E-9 5 15
19 7542250 Tyrosine phosphorylation regulates the adhesions of ras-transformed breast epithelia. Pubmed 1.545E-12 8.634E-10 8.704E-9 2.072E-8 4 5
20 12604612 N-cadherin-catenin complexes form prior to cleavage of the proregion and transport to the plasma membrane. Pubmed 1.545E-12 8.634E-10 8.704E-9 2.072E-8 4 5
21 7651399 The tyrosine kinase substrate p120cas binds directly to E-cadherin but not to the adenomatous polyposis coli protein or alpha-catenin. Pubmed 1.545E-12 8.634E-10 8.704E-9 2.072E-8 4 5
22 10910767 Amino-terminal domain of classic cadherins determines the specificity of the adhesive interactions. Pubmed 1.545E-12 8.634E-10 8.704E-9 2.072E-8 4 5
23 9615388 Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Pubmed 1.545E-12 8.634E-10 8.704E-9 2.072E-8 4 5
24 7890674 The APC protein and E-cadherin form similar but independent complexes with alpha-catenin, beta-catenin, and plakoglobin. Pubmed 1.545E-12 8.634E-10 8.704E-9 2.072E-8 4 5
25 21521738 p120 catenin is required for normal renal tubulogenesis and glomerulogenesis. Pubmed 2.429E-12 1.303E-9 1.314E-8 3.258E-8 5 19
26 11226248 Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex. Pubmed 4.632E-12 2.390E-9 2.409E-8 6.213E-8 4 6
27 15479741 Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. Pubmed 1.080E-11 4.830E-9 4.869E-8 1.449E-7 4 7
28 12052883 The cell adhesion molecule M-cadherin is not essential for muscle development and regeneration. Pubmed 1.080E-11 4.830E-9 4.869E-8 1.449E-7 4 7
29 25038041 p120-catenin-dependent junctional recruitment of Shroom3 is required for apical constriction during lens pit morphogenesis. Pubmed 1.080E-11 4.830E-9 4.869E-8 1.449E-7 4 7
30 24046456 Flotillin microdomains stabilize cadherins at cell-cell junctions. Pubmed 1.080E-11 4.830E-9 4.869E-8 1.449E-7 4 7
31 15148305 Mammalian Fat1 cadherin regulates actin dynamics and cell-cell contact. Pubmed 2.159E-11 8.275E-9 8.343E-8 2.896E-7 4 8
32 21849546 The postnatal accumulation of junctional E-cadherin is inversely correlated with the capacity for supporting cells to convert directly into sensory hair cells in mammalian balance organs. Pubmed 2.159E-11 8.275E-9 8.343E-8 2.896E-7 4 8
33 25827072 FBXO11 promotes ubiquitination of the Snail family of transcription factors in cancer progression and epidermal development. Pubmed 2.159E-11 8.275E-9 8.343E-8 2.896E-7 4 8
34 8821035 Expression of catenins during mouse embryonic development and in adult tissues. Pubmed 2.159E-11 8.275E-9 8.343E-8 2.896E-7 4 8
35 24965120 HIV-1 Tat C phosphorylates VE-cadherin complex and increases human brain microvascular endothelial cell permeability. Pubmed 2.159E-11 8.275E-9 8.343E-8 2.896E-7 4 8
36 18794329 EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition. Pubmed 2.467E-11 9.192E-9 9.266E-8 3.309E-7 5 29
37 19170756 SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis. Pubmed 3.885E-11 1.271E-8 1.281E-7 5.211E-7 4 9
38 19705445 Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos. Pubmed 3.885E-11 1.271E-8 1.281E-7 5.211E-7 4 9
39 18816447 Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures. Pubmed 3.885E-11 1.271E-8 1.281E-7 5.211E-7 4 9
40 12695331 NF2 deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions. Pubmed 3.885E-11 1.271E-8 1.281E-7 5.211E-7 4 9
41 19321785 E-Cadherin regulates neural stem cell self-renewal. Pubmed 3.885E-11 1.271E-8 1.281E-7 5.211E-7 4 9
42 22736606 Ocular anterior segment dysgenesis upon ablation of p120 catenin in neural crest cells. Pubmed 6.471E-11 2.067E-8 2.083E-7 8.680E-7 4 10
43 14657280 Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways. Pubmed 1.016E-10 3.098E-8 3.123E-7 1.363E-6 4 11
44 15525667 Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast. Pubmed 1.016E-10 3.098E-8 3.123E-7 1.363E-6 4 11
45 18849982 Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Pubmed 1.524E-10 4.443E-8 4.479E-7 2.044E-6 4 12
46 12707304 Defining desmosomal plakophilin-3 interactions. Pubmed 1.524E-10 4.443E-8 4.479E-7 2.044E-6 4 12
47 9615235 Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity. Pubmed 2.200E-10 5.901E-8 5.949E-7 2.950E-6 4 13
48 17057644 A distinct PAR complex associates physically with VE-cadherin in vertebrate endothelial cells. Pubmed 2.200E-10 5.901E-8 5.949E-7 2.950E-6 4 13
49 15630473 A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. Pubmed 2.200E-10 5.901E-8 5.949E-7 2.950E-6 4 13
50 22972715 Membrane β-catenin and adherens junctions in early gonadal patterning. Pubmed 2.200E-10 5.901E-8 5.949E-7 2.950E-6 4 13
Show 45 more annotations

9: Interaction [Display Chart] 29 input genes in category / 2135 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CTNNA3 CTNNA3 interactions 1.383E-16 2.954E-13 2.435E-12 2.954E-13 8 31
2 int:CTNNA1 CTNNA1 interactions 3.097E-16 3.306E-13 2.726E-12 6.613E-13 10 98
3 int:JUP JUP interactions 1.690E-14 1.202E-11 9.913E-11 3.607E-11 11 213
4 int:PTPRQ PTPRQ interactions 2.037E-13 1.087E-10 8.963E-10 4.349E-10 6 18
5 int:CDH3 CDH3 interactions 2.055E-12 8.774E-10 7.233E-9 4.387E-9 5 10
6 int:RYK RYK interactions 1.154E-10 4.104E-8 3.383E-7 2.464E-7 7 92
7 int:CTNND1 CTNND1 interactions 1.346E-10 4.104E-8 3.383E-7 2.873E-7 7 94
8 int:ARVCF ARVCF interactions 3.411E-10 9.104E-8 7.505E-7 7.284E-7 5 24
9 int:PKP4 PKP4 interactions 4.248E-10 1.008E-7 8.306E-7 9.068E-7 6 58
10 int:CDH5 CDH5 interactions 7.692E-9 1.642E-6 1.354E-5 1.642E-5 6 93
11 int:PTPRM PTPRM interactions 1.042E-8 2.023E-6 1.668E-5 2.226E-5 4 16
12 int:CDH8 CDH8 interactions 1.749E-8 3.111E-6 2.565E-5 3.733E-5 4 18
13 int:PKP2 PKP2 interactions 7.383E-8 1.213E-5 9.996E-5 1.576E-4 5 67
14 int:GNA13 GNA13 interactions 9.222E-8 1.406E-5 1.159E-4 1.969E-4 5 70
15 int:FER FER interactions 1.545E-7 2.199E-5 1.813E-4 3.298E-4 4 30
16 int:CTNNA2 CTNNA2 interactions 1.772E-7 2.225E-5 1.834E-4 3.783E-4 4 31
17 int:PKD1 PKD1 interactions 1.772E-7 2.225E-5 1.834E-4 3.783E-4 4 31
18 int:PTPRJ PTPRJ interactions 2.603E-7 3.087E-5 2.545E-4 5.557E-4 4 34
19 int:CDH2 CDH2 interactions 2.762E-7 3.103E-5 2.558E-4 5.896E-4 5 87
20 int:CDH15 CDH15 interactions 8.609E-7 9.190E-5 7.576E-4 1.838E-3 3 12
21 int:ERBIN ERBIN interactions 9.322E-7 9.478E-5 7.813E-4 1.990E-3 5 111
22 int:PSEN1 PSEN1 interactions 1.210E-6 1.175E-4 9.684E-4 2.584E-3 5 117
23 int:CDON CDON interactions 1.421E-6 1.319E-4 1.088E-3 3.034E-3 3 14
24 int:RAB8B RAB8B interactions 1.489E-6 1.324E-4 1.092E-3 3.178E-3 4 52
25 int:MUC1 MUC1 interactions 1.735E-6 1.482E-4 1.222E-3 3.705E-3 4 54
26 int:DSC3 DSC3 interactions 2.182E-6 1.737E-4 1.432E-3 4.658E-3 3 16
27 int:AXIN1 AXIN1 interactions 2.197E-6 1.737E-4 1.432E-3 4.691E-3 5 132
28 int:ARHGAP32 ARHGAP32 interactions 2.317E-6 1.767E-4 1.457E-3 4.947E-3 4 58
29 int:PIK3R1 PIK3R1 interactions 2.765E-6 2.036E-4 1.678E-3 5.904E-3 6 251
30 int:PKP3 PKP3 interactions 3.235E-6 2.302E-4 1.898E-3 6.907E-3 4 63
31 int:LIMA1 LIMA1 interactions 3.865E-6 2.662E-4 2.194E-3 8.252E-3 6 266
32 int:PTPRF PTPRF interactions 5.229E-6 3.489E-4 2.876E-3 1.116E-2 4 71
33 int:PCDHGB1 PCDHGB1 interactions 5.531E-6 3.578E-4 2.950E-3 1.181E-2 4 72
34 int:PTPN1 PTPN1 interactions 6.368E-6 3.999E-4 3.296E-3 1.359E-2 5 164
35 int:MYO7A MYO7A interactions 6.847E-6 4.072E-4 3.357E-3 1.462E-2 3 23
36 int:MYO1B MYO1B interactions 6.866E-6 4.072E-4 3.357E-3 1.466E-2 4 76
37 int:AJAP1 AJAP1 interactions 7.765E-6 4.392E-4 3.620E-3 1.658E-2 2 3
38 int:VEZT VEZT interactions 7.817E-6 4.392E-4 3.620E-3 1.669E-2 3 24
39 int:GRIK2 GRIK2 interactions 1.002E-5 5.485E-4 4.521E-3 2.139E-2 3 26
40 int:KIFAP3 KIFAP3 interactions 1.124E-5 5.998E-4 4.944E-3 2.399E-2 4 86
41 int:ACTG1 ACTG1 interactions 1.205E-5 6.254E-4 5.156E-3 2.573E-2 5 187
42 int:MYL6 MYL6 interactions 1.231E-5 6.254E-4 5.156E-3 2.629E-2 4 88
43 int:CTNND2 CTNND2 interactions 1.260E-5 6.254E-4 5.156E-3 2.689E-2 3 28
44 int:GSK3B GSK3B interactions 1.396E-5 6.514E-4 5.370E-3 2.980E-2 6 333
45 int:PTPRU PTPRU interactions 1.403E-5 6.514E-4 5.370E-3 2.996E-2 3 29
46 int:CTNNBIP1 CTNNBIP1 interactions 1.403E-5 6.514E-4 5.370E-3 2.996E-2 3 29
47 int:KIF3B KIF3B interactions 2.086E-5 9.477E-4 7.813E-3 4.454E-2 3 33
48 int:SIPA1L3 SIPA1L3 interactions 2.958E-5 1.316E-3 1.085E-2
6.315E-2
 3 37
49 int:APC APC interactions 3.263E-5 1.422E-3 1.172E-2
6.967E-2
 5 230
50 int:GNA12 GNA12 interactions 3.472E-5 1.482E-3 1.222E-2
7.412E-2
 3 39
Show 45 more annotations

10: Cytoband [Display Chart] 30 input genes in category / 28 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16q22.1 16q22.1 1.319E-4 3.692E-3 1.450E-2 3.692E-3 3 114
2 6q22.2-q22.3 6q22.2-q22.3 8.655E-4 1.212E-2 4.759E-2 2.423E-2 1 1
3 12q15-q21 12q15-q21 2.594E-3 2.420E-2
9.505E-2
7.264E-2
 1 3
4 5q21-q22 5q21-q22 3.458E-3 2.420E-2
9.505E-2
9.682E-2
 1 4
5 22q13.3 22q13.3 5.182E-3 2.820E-2
1.108E-1
1.451E-1
 1 6
6 Xq21.3 Xq21.3 6.043E-3 2.820E-2
1.108E-1
1.692E-1
 1 7
7 14q32.1 14q32.1 9.481E-3 3.792E-2
1.489E-1
2.655E-1
 1 11
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 21 input genes in category / 180 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 YTCCCRNNAGGY UNKNOWN YTCCCRNNAGGY UNKNOWN 2.707E-4 4.873E-2
2.813E-1
 4.873E-2 3 60

12: Gene Family [Display Chart] 23 input genes in category / 22 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 409 Armadillo repeat containing genenames.org 1.890E-9 4.159E-8 1.535E-7 4.159E-8 5 43
2 1185 CD molecules|Type I classical cadherins genenames.org 1.762E-8 1.938E-7 7.152E-7 3.876E-7 3 5
3 813 Fibronectin type III domain containing|Protein tyrosine phosphatases, receptor type genenames.org 2.312E-6 1.696E-5 6.259E-5 5.087E-5 3 21
4 21 Non-clustered protocadherins genenames.org 1.001E-4 5.507E-4 2.032E-3 2.203E-3 2 12
5 555 Receptor Tyrosine Kinases|Fibronectin type III domain containing|V-set domain containing|Immunoglobulin like domain containing genenames.org 1.039E-3 4.570E-3 1.687E-2 2.285E-2 3 160
6 471 CD molecules|Tumor necrosis factor superfamily genenames.org 1.384E-3 5.074E-3 1.873E-2 3.045E-2 4 394
7 1189 Adhesion G protein-coupled receptors, subfamily C|CELSR cadherins genenames.org 3.788E-3 1.042E-2 3.845E-2
8.333E-2
 1 3
8 913 Adhesion G protein-coupled receptors, subfamily C|CELSR cadherins genenames.org 3.788E-3 1.042E-2 3.845E-2
8.333E-2
 1 3
9 1224 WD repeat domain containing|Scribble complex genenames.org 5.047E-3 1.234E-2 4.554E-2
1.110E-1
 1 4
10 1361 Armadillo repeat containing|NineTeen complex genenames.org 8.817E-3 1.763E-2
6.508E-2
1.940E-1
 1 7
11 1188 Desmosomal cadherins genenames.org 8.817E-3 1.763E-2
6.508E-2
1.940E-1
 1 7
12 1259 SNAG transcriptional repressors genenames.org 1.257E-2 2.305E-2
8.507E-2
2.766E-1
 1 10
13 1220 Membrane associated guanylate kinases|PDZ domain containing genenames.org 1.564E-2 2.564E-2
9.463E-2
3.440E-1
 2 152
14 1186 CD molecules|Type II classical cadherins genenames.org 1.632E-2 2.564E-2
9.463E-2
3.589E-1
 1 13
15 672 Parkinson disease associated genes|Ubiquitin C-terminal hydrolases genenames.org 2.004E-2 2.940E-2
1.085E-1
4.410E-1
 1 16
16 694 Protein phosphatase 1 regulatory subunits genenames.org 2.171E-2 2.985E-2
1.102E-1
4.777E-1
 2 181
17 594 Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing genenames.org 2.447E-2 3.167E-2
1.169E-1
5.383E-1
 2 193
18 1253 Scavenger receptors genenames.org 3.360E-2 4.107E-2
1.516E-1
7.392E-1
 1 27
Show 13 more annotations

13: Coexpression [Display Chart] 30 input genes in category / 2918 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16488994-SuppTable1b Mouse Lung Lu06 856genes Array MEO430Av2 GeneSigDB 4.413E-12 1.288E-8 1.102E-7 1.288E-8 11 443
2 16488994-SuppTable1a Mouse Lung Lu06 856genes Array MG U74Av2 GeneSigDB 1.456E-10 2.124E-7 1.817E-6 4.248E-7 10 449
3 19861896-Table2 Human Brain Castells09 83genes GeneSigDB 3.906E-8 3.799E-5 3.251E-4 1.140E-4 5 74
4 M1790 Epithelial and mesenchymal markers up-regulated in MEF cells (embryonic fibroblasts) after knockout of PRKAR1A [GeneID=5573]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.644E-7 9.402E-5 8.044E-4 4.796E-4 3 9
5 M347 Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to HNE and H2O2 [PubChem=5283344;784]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.830E-7 9.402E-5 8.044E-4 5.339E-4 4 39
6 M5915 Genes encoding components of apical junction complex. MSigDB H: Hallmark Gene Sets (v6.0) 1.933E-7 9.402E-5 8.044E-4 5.641E-4 6 200
7 19038878-SuppTable3 Human Leukemia Lenz08 385genes GeneSigDB 2.527E-7 1.053E-4 9.014E-4 7.374E-4 7 349
8 17210682-Table2b Human Colon Grade07 101genes GeneSigDB 9.278E-7 3.384E-4 2.896E-3 2.707E-3 4 58
9 19286929-SuppTable2a Mouse Lung Rangasamy09 168genes GeneSigDB 1.525E-6 4.944E-4 4.230E-3 4.450E-3 5 154
10 17018611-Table2 Human Breast MorenoBueno06 117genes GeneSigDB 3.929E-6 1.147E-3 9.810E-3 1.147E-2 4 83
11 M7279 Genes up-regulated in double positive thymocytes: wildtype versus TCF12 [GeneID=6938] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.487E-6 1.456E-3 1.245E-2 1.601E-2 5 200
12 14750170-Table1 Mouse Intestine DeGiovanni04 30genes GeneSigDB 6.305E-6 1.533E-3 1.312E-2 1.840E-2 3 28
13 19861896-SuppTable1 Human Brain Castells09 424gebes GeneSigDB 7.219E-6 1.599E-3 1.368E-2 2.106E-2 6 373
14 19204204-SupplementaryTable2 Human Breast Parker09 412genes IntrinsicGenes Perou2000 GeneSigDB 7.672E-6 1.599E-3 1.368E-2 2.239E-2 6 377
15 17349526-Table2 Human Bladder Ewis06 44genes GeneSigDB 1.146E-5 2.228E-3 1.907E-2 3.343E-2 3 34
16 15326482-Table4 Human Liver Nakagawa04 53genes GeneSigDB 1.364E-5 2.488E-3 2.129E-2 3.982E-2 3 36
17 M10702 Genes down-regulated in metastases from malignant melanoma compared to the primary tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.882E-5 3.230E-3 2.763E-2
5.490E-2
 5 258
18 18794132-Table1 Human Breast Shivapurkar08 43genes GeneSigDB 2.028E-5 3.288E-3 2.813E-2
5.918E-2
 3 41
19 19525979-SuppTable2 Human Lung Baras09 50genes SCCvsBSM GeneSigDB 2.344E-5 3.453E-3 2.954E-2
6.840E-2
 3 43
20 16138077-Table2 Mouse Liver Gresh05 06genes GeneSigDB 2.430E-5 3.453E-3 2.954E-2
7.091E-2
 2 6
21 M4306 Genes down-regulated in HMLE cells (immortalized nontransformed mammary epithelium) after E-cadhedrin (CDH1) [GeneID=999] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.485E-5 3.453E-3 2.954E-2
7.252E-2
 6 464
22 M18517 Genes changed between developmental stages of Valpha14i natural killer T lymphocyte cells (NKT). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.834E-5 3.759E-3 3.216E-2
8.270E-2
 6 475
23 16397240-Table1e Human Colon Grade06 58genes GeneSigDB 3.271E-5 4.150E-3 3.550E-2
9.544E-2
 3 48
24 M5896 Genes up-regulated in response to TGFB1 [GeneID=7040]. MSigDB H: Hallmark Gene Sets (v6.0) 4.666E-5 5.673E-3 4.854E-2
1.362E-1
 3 54
25 M4737 ECM related genes up-regulated early (within 30 min) in dermal fibroblasts after addition of TGFB1 [GeneID=7040]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.784E-5 6.751E-3
5.777E-2
1.688E-1
 3 58
26 20553613-AF-1 Human pancreas Kalinina03 66genes GeneSigDB 7.065E-5 7.853E-3
6.719E-2
2.062E-1
 3 62
27 20521089-SuppTable1b Human Breast Blick10 11genes EMT down GeneSigDB 7.267E-5 7.853E-3
6.719E-2
2.120E-1
 2 10
28 M1417 Genes down-regulated during epithelial to mesenchymal transition (EMT) induced by TGFB1 [GeneID=7040] in the EpH4 cells (mammary epithelium cell line transformed by HRAS [GeneID=3265]). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.518E-5 8.877E-3
7.596E-2
2.486E-1
 3 66
29 M3848 Genes down-regulated during the course of maturation of monocyte-derived dendritic cells (DC) in response to inflammatory stimuli (cluster D). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.313E-5 9.371E-3
8.018E-2
2.718E-1
 3 68
30 18435859-ShorterGeneList Mouse Breast Piechocki08 558genes GeneSigDB 1.126E-4 1.038E-2
8.881E-2
3.284E-1
 5 376
31 M7674 Genes up-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795]. MSigDB C7: Immunologic Signatures (v6.0) 1.245E-4 1.038E-2
8.881E-2
3.633E-1
 4 200
32 M6200 Genes up-regulated in polymorphonuclear leukocytes (24h): treated by heat killed HC60 cell (promyelocytic leukemia) lysate versus A. phagocytophilum infection. MSigDB C7: Immunologic Signatures (v6.0) 1.245E-4 1.038E-2
8.881E-2
3.633E-1
 4 200
33 M6212 Genes up-regulated in polymorphonuclear leukocytes (3h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 1.245E-4 1.038E-2
8.881E-2
3.633E-1
 4 200
34 M7283 Genes up-regulated in monocytes after HCMV infection: untreated versus pre-treated with Ly294002 [PubChem=3973]. MSigDB C7: Immunologic Signatures (v6.0) 1.245E-4 1.038E-2
8.881E-2
3.633E-1
 4 200
35 M7501 Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus wildtype Tfh cells. MSigDB C7: Immunologic Signatures (v6.0) 1.245E-4 1.038E-2
8.881E-2
3.633E-1
 4 200
36 M7061 Metastatic propensity markers of head and neck squamous cell carcinoma (HNSCC): up-regulated in metastatic vs non-metastatic tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.455E-4 1.155E-2
9.884E-2
4.247E-1
 3 79
37 19489030-SuppTable3 Human Prostate Chambers09 18genes GeneSigDB 1.465E-4 1.155E-2
9.884E-2
4.274E-1
 2 14
38 19225562-TableS1 Human Breast Martin09 485genes GeneSigDB 1.804E-4 1.385E-2
1.185E-1
5.265E-1
 5 416
39 15833844-Table2S Human Esophagus Kimchi05 96genes GeneSigDB 1.872E-4 1.401E-2
1.198E-1
5.463E-1
 3 86
40 M12924 Genes down-regulated in primary granulosa cells in response to forskolin [PubChem=47936]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.004E-4 1.462E-2
1.251E-1
5.847E-1
 3 88
41 M2299 Genes up-regulated in 9.5 days post coitus (dpc) embryos with COMMD1 [GeneID=150684] knockout compared to normal 9.5 dpc embryos. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.072E-4 1.467E-2
1.255E-1
6.046E-1
 3 89
42 19101988-TableS2 Human Breast Habermann09 18genes GeneSigDB 2.184E-4 1.467E-2
1.255E-1
6.372E-1
 2 17
43 16265353-Table1 Human Bladder Aaboe05 20genes TumorvNorm GeneSigDB 2.184E-4 1.467E-2
1.255E-1
6.372E-1
 2 17
44 17409455-TableS2 Human Breast Winter07 126genes GeneSigDB 2.213E-4 1.467E-2
1.255E-1
6.456E-1
 3 91
45 15374877-Table1 Human StemCell Manalo05 129genes GeneSigDB 2.285E-4 1.482E-2
1.268E-1
6.668E-1
 3 92
46 M15491 Genes down-regulated in MDA-MB-231 cells (breast cancer) after knockdown of SATB1 [GeneID=6304] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.390E-4 1.516E-2
1.297E-1
6.973E-1
 5 442
47 14676830-Table6 Human HeadandNeck Cromer04 18genes GeneSigDB 2.455E-4 1.524E-2
1.304E-1
7.163E-1
 2 18
48 18724390-Table3 Human Bladder Wu08 24genes GeneSigDB 3.043E-4 1.850E-2
1.583E-1
8.881E-1
 2 20
49 15897907-SuppTable5 Human Breast Farmer05 269genes basal apocrine luminal GeneSigDB 3.295E-4 1.962E-2
1.678E-1
9.615E-1
 4 258
50 17161497-Table3 Human Lung Dracheva07 24genes GeneSigDB 3.361E-4 1.962E-2
1.678E-1
9.808E-1
 2 21
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 30 input genes in category / 2689 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Facebase RNAseq e10.5 Olfactory Pit 500 K3 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 500 k-means-cluster#3 FaceBase_RNAseq 3.868E-8 9.012E-5 7.637E-4 1.040E-4 6 144
2 Facebase RNAseq e9.5 Olfactory Placode 1000 K3 FacebaseRNAseq e9.5 Olfactory Placode top-relative-expression-ranked 1000 k-means-cluster#3 FaceBase_RNAseq 9.015E-8 9.012E-5 7.637E-4 2.424E-4 7 283
3 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Subtype Flt1.Vwf Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Subtype Flt1.Vwf Top 200 Genes 1.341E-7 9.012E-5 7.637E-4 3.605E-4 7 300
4 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1.Vwf Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1.Vwf Top 200 Genes BrainMap 1.341E-7 9.012E-5 7.637E-4 3.605E-4 7 300
5 Facebase RNAseq e9.5 Olfactory Placode 2500 K5 FacebaseRNAseq e9.5 Olfactory Placode top-relative-expression-ranked 2500 k-means-cluster#5 FaceBase_RNAseq 8.000E-7 4.302E-4 3.646E-3 2.151E-3 7 391
6 Facebase RNAseq e10.5 Olfactory Pit 1000 K1 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 1000 k-means-cluster#1 FaceBase_RNAseq 1.231E-6 5.517E-4 4.676E-3 3.310E-3 6 259
7 GSM777059 500 Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 1.731E-6 6.648E-4 5.634E-3 4.654E-3 7 439
8 GSM777063 500 Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4 Immgen.org, GSE15907 2.039E-6 6.848E-4 5.803E-3 5.484E-3 7 450
9 Lung Development Lungmap - Mouse FluidigmC1 Endothelial Overall Top 500 Genes Lung Development Lungmap - Mouse FluidigmC1 Endothelial Overall Top 500 Genes 2.292E-6 6.848E-4 5.803E-3 6.163E-3 7 458
10 Facebase RNAseq e10.5 Olfactory Pit 500 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 500 FaceBase_RNAseq 3.827E-6 1.029E-3 8.721E-3 1.029E-2 7 495
11 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/macrophage Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/macrophage Tabula Muris Consortium 4.467E-6 1.092E-3 9.253E-3 1.201E-2 5 181
12 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Tongue Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Tongue Tabula Muris Consortium 5.516E-6 1.236E-3 1.047E-2 1.483E-2 5 189
13 Mouse Lung Development Lungmap Mouse Fluidigm Endothelial Subtype endothelial cells B PND01-03 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Endothelial Subtype endothelial cells B PND01-03 Top 200 Genes 8.331E-6 1.723E-3 1.460E-2 2.240E-2 6 361
14 GSM777041 500 Stromal Cells, Ep.MEChi.Th, CD45- EpCAm+ Ly51- MHCIIhi, Thymus, avg-2 Immgen.org, GSE15907 1.184E-5 2.274E-3 1.927E-2 3.183E-2 6 384
15 GSM854302 500 Stromal Cells, Ep.MEChi.Th, CD45-EpCAm+Ly51-MHCIIhi, Thymus, avg-1 Immgen.org, GSE15907 1.739E-5 3.117E-3 2.642E-2 4.676E-2 6 411
16 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1 SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1 SubstantiaNigra Top 200 Genes BrainMap 2.673E-5 4.479E-3 3.796E-2
7.187E-2
 5 262
17 Facebase RNAseq ratio e9.5 MandibularArch vs MaxillaryArch 1000 K3 FacebaseRNAseq ratio e9.5 MandibularArch vs MaxillaryArch top-relative-expression-ranked 1000 k-means-cluster#3 FaceBase_RNAseq 2.832E-5 4.479E-3 3.796E-2
7.614E-2
 4 129
18 GSM777032 500 Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5 Immgen.org, GSE15907 3.119E-5 4.660E-3 3.949E-2
8.387E-2
 6 456
19 Facebase RNAseq e9.5 Facial Mesenchyne 500 K5 FacebaseRNAseq e9.5 Facial Mesenchyne top-relative-expression-ranked 500 k-means-cluster#5 FaceBase_RNAseq 4.946E-5 7.000E-3
5.932E-2
1.330E-1
 3 52
20 Facebase RNAseq e9.5 Maxillary Arch 2500 K3 FacebaseRNAseq e9.5 Maxillary Arch top-relative-expression-ranked 2500 k-means-cluster#3 FaceBase_RNAseq 5.513E-5 7.413E-3
6.282E-2
1.483E-1
 5 305
21 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 2500 K4 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 2500 k-means-cluster#4 FaceBase_RNAseq 6.520E-5 7.999E-3
6.779E-2
1.753E-1
 5 316
22 Facebase RNAseq e8.5 Floor Plate 500 K5 FacebaseRNAseq e8.5 Floor Plate top-relative-expression-ranked 500 k-means-cluster#5 FaceBase_RNAseq 7.229E-5 7.999E-3
6.779E-2
1.944E-1
 3 59
23 facebase RNAseq e9.5 OlfPlac 2500 K2 facebase RNAseq e9.5 OlfPlac 2500 K2 Gudmap RNAseq 7.888E-5 7.999E-3
6.779E-2
2.121E-1
 5 329
24 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma /Poorly Differentiated or Epithelioid Leiomyosarcoma/1/4 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma /Poorly Differentiated or Epithelioid Leiomyosarcoma/1/4 TCGA-Bone and Soft Tissue 8.798E-5 7.999E-3
6.779E-2
2.366E-1
 3 63
25 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1 Hippocampus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1 Hippocampus Top 200 Genes BrainMap 8.833E-5 7.999E-3
6.779E-2
2.375E-1
 5 337
26 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn GlobusPallidus Top 200 Genes BrainMap 9.998E-5 7.999E-3
6.779E-2
2.689E-1
 5 346
27 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Overall Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Overall Top 200 Genes 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
28 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. Endothelial Stalk. Top 200 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. Endothelial Stalk. Top 200 BrainMap 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
29 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. Endothelial Stalk. Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. Endothelial Stalk. Overall Top 200 Genes BrainMap 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
30 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk Endothelial Stalk Top 200 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk Endothelial Stalk Top 200 BrainMap 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
31 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Endothelial Stalk BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Endothelial Stalk BrainMap 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
32 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Overall Top 200 Genes BrainMap 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
33 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk Endothelial Stalk Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk Endothelial Stalk Overall Top 200 Genes BrainMap 1.014E-4 7.999E-3
6.779E-2
2.727E-1
 4 179
34 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Kidney/endothelial cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Kidney/endothelial cell Tabula Muris Consortium 1.036E-4 7.999E-3
6.779E-2
2.786E-1
 4 180
35 gudmap developingGonad P2 testes 1000 k2 DevelopingGonad P2 testes emap-30171 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.041E-4 7.999E-3
6.779E-2
2.800E-1
 5 349
36 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/epithelial cell of lung Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/epithelial cell of lung Tabula Muris Consortium 1.105E-4 8.204E-3
6.952E-2
2.970E-1
 4 183
37 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/endothelial cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Brain Non-Myeloid/endothelial cell Tabula Muris Consortium 1.201E-4 8.204E-3
6.952E-2
3.228E-1
 4 187
38 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Skin Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Skin Tabula Muris Consortium 1.226E-4 8.204E-3
6.952E-2
3.295E-1
 4 188
39 Facebase RNAseq e9.5 Olfactory Placode 500 K2 FacebaseRNAseq e9.5 Olfactory Placode top-relative-expression-ranked 500 k-means-cluster#2 FaceBase_RNAseq 1.226E-4 8.204E-3
6.952E-2
3.295E-1
 4 188
40 gudmap developingGonad e18.5 testes 1000 k3 DevelopingGonad e18.5 testes emap-11164 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.236E-4 8.204E-3
6.952E-2
3.323E-1
 5 362
41 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Bladder/bladder urothelial cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Bladder/bladder urothelial cell Tabula Muris Consortium 1.251E-4 8.204E-3
6.952E-2
3.363E-1
 4 189
42 Facebase RNAseq e8.5 Floor Plate 1000 K5 FacebaseRNAseq e8.5 Floor Plate top-relative-expression-ranked 1000 k-means-cluster#5 FaceBase_RNAseq 1.310E-4 8.389E-3
7.109E-2
3.523E-1
 3 72
43 GSM605820 500 Myeloid Cells, DC.103+11b-.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3 Immgen.org, GSE15907 1.628E-4 1.015E-2
8.602E-2
4.378E-1
 5 384
44 Kidney10XCellRanger Six2TGC TSC1 E14 UB UB Subtype E14-Six2TGC Tsc1-UB-C8-KC7 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 UB UB Subtype E14-Six2TGC Tsc1-UB-C8-KC7 Top 200 Genes 1.678E-4 1.015E-2
8.602E-2
4.511E-1
 4 204
45 gudmap developingKidney e15.5 cortic collect duct 500 DevelopingKidney e15.5 cortic collect duct emap-28132 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.750E-4 1.015E-2
8.602E-2
4.705E-1
 5 390
46 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1.Lrg1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1.Lrg1 Top 200 Genes BrainMap 1.774E-4 1.015E-2
8.602E-2
4.771E-1
 4 207
47 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Subtype Flt1.Lrg1 Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Subtype Flt1.Lrg1 Top 200 Genes 1.774E-4 1.015E-2
8.602E-2
4.771E-1
 4 207
48 Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial Subtype endothelial cells C PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Endothelial Endothelial Subtype endothelial cells C PND07-28 Top 200 Genes 1.909E-4 1.069E-2
9.063E-2
5.134E-1
 4 211
49 GSM854269 500 Myeloid Cells, DC.103-11b+24+.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24+, Lung, avg-2 Immgen.org, GSE15907 2.061E-4 1.099E-2
9.313E-2
5.543E-1
 5 404
50 Facebase RNAseq e10.5 Olfactory Pit 2500 K5 FacebaseRNAseq e10.5 Olfactory Pit top-relative-expression-ranked 2500 k-means-cluster#5 FaceBase_RNAseq 2.109E-4 1.099E-2
9.313E-2
5.671E-1
 5 406
Show 45 more annotations

15: Computational [Display Chart] 21 input genes in category / 144 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M414 MODULE 122 Adhesion molecules. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.174E-9 1.321E-6 7.333E-6 1.321E-6 7 141
2 M4515 MODULE 324 Metal / Ca ion binding. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.502E-6 4.681E-4 2.598E-3 9.363E-4 5 133

16: MicroRNA [Display Chart] 30 input genes in category / 1042 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-885-5p:PITA hsa-miR-885-5p:PITA TOP PITA 6.865E-7 6.459E-4 4.862E-3 7.153E-4 4 165
2 hsa-miR-582-5p:TargetScan hsa-miR-582-5p TargetScan 1.240E-6 6.459E-4 4.862E-3 1.292E-3 5 457
3 hsa-miR-34c-3p:PITA hsa-miR-34c-3p:PITA TOP PITA 2.894E-6 8.658E-4 6.516E-3 3.016E-3 4 237
4 hsa-miR-432-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.323E-6 8.658E-4 6.516E-3 3.463E-3 3 69
5 hsa-miR-3191:mirSVR highEffct hsa-miR-3191:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.032E-5 2.408E-3 1.812E-2 2.117E-2 3 126
6 hsa-miR-590-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.051E-5 2.408E-3 1.812E-2 2.137E-2 4 390
7 hsa-miR-1284:PITA hsa-miR-1284:PITA TOP PITA 2.920E-5 2.408E-3 1.812E-2 3.043E-2 4 427
8 hsa-miR-125b-5p:Functional MTI Functional MTI miRTarbase 3.028E-5 2.408E-3 1.812E-2 3.155E-2 4 431
9 hsa-miR-204:PITA hsa-miR-204:PITA TOP PITA 3.028E-5 2.408E-3 1.812E-2 3.155E-2 4 431
10 hsa-miR-211:PITA hsa-miR-211:PITA TOP PITA 3.028E-5 2.408E-3 1.812E-2 3.155E-2 4 431
11 hsa-miR-494-3p:TargetScan hsa-miR-494-3p TargetScan 3.459E-5 2.408E-3 1.812E-2 3.604E-2 4 446
12 hsa-miR-591:mirSVR highEffct hsa-miR-591:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.550E-5 2.408E-3 1.812E-2 3.699E-2 4 449
13 hsa-miR-501-3p:TargetScan hsa-miR-501-3p TargetScan 3.626E-5 2.408E-3 1.812E-2 3.778E-2 3 153
14 hsa-miR-502-3p:TargetScan hsa-miR-502-3p TargetScan 3.626E-5 2.408E-3 1.812E-2 3.778E-2 3 153
15 hsa-miR-208b-3p:TargetScan hsa-miR-208b-3p TargetScan 4.298E-5 2.408E-3 1.812E-2 4.479E-2 3 162
16 hsa-miR-208a-3p:TargetScan hsa-miR-208a-3p TargetScan 4.298E-5 2.408E-3 1.812E-2 4.479E-2 3 162
17 hsa-miR-219-5p:mirSVR highEffct hsa-miR-219-5p:mirSVR conserved highEffect-0.5 MicroRNA.org 4.563E-5 2.408E-3 1.812E-2 4.754E-2 4 479
18 hsa-miR-199a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 4.622E-5 2.408E-3 1.812E-2 4.816E-2 3 166
19 hsa-miR-502-3p:PITA hsa-miR-502-3p:PITA TOP PITA 4.874E-5 2.408E-3 1.812E-2
5.079E-2
 3 169
20 hsa-miR-501-3p:PITA hsa-miR-501-3p:PITA TOP PITA 4.960E-5 2.408E-3 1.812E-2
5.169E-2
 3 170
21 hsa-miR-640:PITA hsa-miR-640:PITA TOP PITA 5.225E-5 2.408E-3 1.812E-2
5.444E-2
 3 173
22 GCAAAAA,MIR-129:MSigDB GCAAAAA,MIR-129:MSigDB MSigDB 5.315E-5 2.408E-3 1.812E-2
5.538E-2
 3 174
23 hsa-miR-34c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.315E-5 2.408E-3 1.812E-2
5.538E-2
 3 174
24 hsa-miR-650:PITA hsa-miR-650:PITA TOP PITA 7.565E-5 3.284E-3 2.472E-2
7.883E-2
 3 196
25 hsa-miR-150:PITA hsa-miR-150:PITA TOP PITA 8.031E-5 3.347E-3 2.519E-2
8.368E-2
 3 200
26 hsa-miR-6771-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.644E-4 6.307E-3 4.747E-2
1.714E-1
 3 255
27 hsa-miR-199a-5p:PITA hsa-miR-199a-5p:PITA TOP PITA 1.721E-4 6.307E-3 4.747E-2
1.794E-1
 3 259
28 hsa-miR-199b-5p:PITA hsa-miR-199b-5p:PITA TOP PITA 1.721E-4 6.307E-3 4.747E-2
1.794E-1
 3 259
29 hsa-miR-4512:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.858E-4 6.307E-3 4.747E-2
1.936E-1
 2 48
30 hsa-miR-150-5p:TargetScan hsa-miR-150-5p TargetScan 1.862E-4 6.307E-3 4.747E-2
1.940E-1
 3 266
31 hsa-miR-618:PITA hsa-miR-618:PITA TOP PITA 1.924E-4 6.307E-3 4.747E-2
2.005E-1
 3 269
32 hsa-miR-376a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.937E-4 6.307E-3 4.747E-2
2.018E-1
 2 49
33 hsa-miR-935:PITA hsa-miR-935:PITA TOP PITA 2.210E-4 6.701E-3
5.043E-2
2.303E-1
 3 282
34 hsa-miR-4684-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.447E-4 6.701E-3
5.043E-2
2.550E-1
 3 292
35 ATGTACA,MIR-493:MSigDB ATGTACA,MIR-493:MSigDB MSigDB 2.497E-4 6.701E-3
5.043E-2
2.602E-1
 3 294
36 hsa-miR-1911:mirSVR highEffct hsa-miR-1911:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.497E-4 6.701E-3
5.043E-2
2.602E-1
 3 294
37 hsa-miR-409-3p:PITA hsa-miR-409-3p:PITA TOP PITA 2.497E-4 6.701E-3
5.043E-2
2.602E-1
 3 294
38 hsa-miR-3935:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.532E-4 6.701E-3
5.043E-2
2.638E-1
 2 56
39 hsa-miR-324-5p:Functional MTI Functional MTI miRTarbase 2.572E-4 6.701E-3
5.043E-2
2.680E-1
 3 297
40 hsa-miR-4775:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.572E-4 6.701E-3
5.043E-2
2.680E-1
 3 297
41 hsa-miR-1259:PITA hsa-miR-1259:PITA TOP PITA 2.971E-4 7.335E-3
5.521E-2
3.096E-1
 3 312
42 TGCTTTG,MIR-330:MSigDB TGCTTTG,MIR-330:MSigDB MSigDB 3.027E-4 7.335E-3
5.521E-2
3.154E-1
 3 314
43 hsa-miR-499a-5p:TargetScan hsa-miR-499a-5p TargetScan 3.027E-4 7.335E-3
5.521E-2
3.154E-1
 3 314
44 hsa-miR-219a-5p:TargetScan hsa-miR-219a-5p TargetScan 3.625E-4 8.584E-3
6.461E-2
3.777E-1
 3 334
45 hsa-miR-1276:PITA hsa-miR-1276:PITA TOP PITA 3.917E-4 9.069E-3
6.826E-2
4.081E-1
 3 343
46 hsa-miR-9-5p:Functional MTI Functional MTI miRTarbase 4.154E-4 9.410E-3
7.082E-2
4.329E-1
 3 350
47 hsa-miR-7849-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.661E-4 1.033E-2
7.778E-2
4.857E-1
 2 76
48 hsa-miR-1280:mirSVR lowEffct hsa-miR-1280:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.960E-4 1.077E-2
8.103E-2
5.168E-1
 3 372
49 hsa-miR-34b:PITA hsa-miR-34b:PITA TOP PITA 5.235E-4 1.099E-2
8.275E-2
5.455E-1
 3 379
50 hsa-miR-127-3p:mirSVR lowEffct hsa-miR-127-3p:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 5.276E-4 1.099E-2
8.275E-2
5.497E-1
 3 380
Show 45 more annotations

17: Drug [Display Chart] 30 input genes in category / 7201 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ctd:C057531 jasplakinolide CTD 4.566E-10 3.288E-6 3.110E-5 3.288E-6 5 31
2 CID000027282 D-glucamine Stitch 3.242E-9 1.167E-5 1.104E-4 2.334E-5 5 45
3 ctd:C001020 N(6),N(6)-dimethyladenine CTD 3.350E-7 6.426E-4 6.079E-3 2.412E-3 3 11
4 ctd:C121479 2,4-dihydroxybenzophenone CTD 4.462E-7 6.426E-4 6.079E-3 3.213E-3 3 12
5 CID000657065 J P C Stitch 4.462E-7 6.426E-4 6.079E-3 3.213E-3 3 12
6 ctd:C107676 deguelin CTD 9.112E-7 9.888E-4 9.353E-3 6.562E-3 5 137
7 ctd:D007631 Chlordecone CTD 1.198E-6 9.888E-4 9.353E-3 8.623E-3 4 61
8 CID000196705 alpha-CaM Stitch 1.279E-6 9.888E-4 9.353E-3 9.210E-3 4 62
9 ctd:C497286 3,4',5-trimethoxystilbene CTD 1.373E-6 9.888E-4 9.353E-3 9.888E-3 3 17
10 ctd:C545357 antroquinonol CTD 1.373E-6 9.888E-4 9.353E-3 9.888E-3 3 17
11 ctd:C014290 hydroxyflutamide CTD 1.953E-6 1.212E-3 1.147E-2 1.407E-2 3 19
12 3556 DN Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 2.020E-6 1.212E-3 1.147E-2 1.455E-2 5 161
13 CID000030956 AC1L1KMJ Stitch 2.195E-6 1.216E-3 1.150E-2 1.581E-2 7 476
14 CID000020518 11-deoxojervine Stitch 3.128E-6 1.609E-3 1.522E-2 2.253E-2 5 176
15 CID000446228 AC1L9JC0 Stitch 3.557E-6 1.668E-3 1.578E-2 2.562E-2 3 23
16 ctd:D018021 Lithium Chloride CTD 3.785E-6 1.668E-3 1.578E-2 2.726E-2 6 329
17 CID000018752 plakin Stitch 3.938E-6 1.668E-3 1.578E-2 2.835E-2 4 82
18 4845 DN Primaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 4.319E-6 1.728E-3 1.634E-2 3.110E-2 5 188
19 7254 UP Talampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; PC3; HT HG-U133A Broad Institute CMAP Up 5.162E-6 1.956E-3 1.850E-2 3.717E-2 5 195
20 ctd:C040424 destruxin B CTD 6.551E-6 2.359E-3 2.231E-2 4.717E-2 3 28
21 ctd:C108339 fludioxonil CTD 8.104E-6 2.779E-3 2.629E-2
5.836E-2
 3 30
22 ctd:C519132 2-(5-benzo(1,3)dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrochloride CTD 9.990E-6 3.270E-3 3.093E-2
7.194E-2
 2 4
23 ctd:C056068 theaflavin CTD 1.086E-5 3.401E-3 3.217E-2
7.822E-2
 3 33
24 ctd:C029216 2-amino-3-methylimidazo(4,5-f)quinoline CTD 1.190E-5 3.571E-3 3.378E-2
8.571E-2
 3 34
25 ctd:C573784 dehydroeffusol CTD 1.664E-5 4.792E-3 4.533E-2
1.198E-1
 2 5
26 CID000448294 AC1L9LT0 Stitch 1.969E-5 5.453E-3
5.158E-2
1.418E-1
 4 123
27 CID000005711 Y-27632 Stitch 2.111E-5 5.631E-3
5.326E-2
1.520E-1
 6 445
28 ctd:C417521 SB 216763 CTD 2.267E-5 5.831E-3
5.516E-2
1.633E-1
 3 42
29 CID000064506 Clark 2 Stitch 2.493E-5 6.191E-3
5.856E-2
1.795E-1
 2 6
30 CID004630071 AC1NDQQF Stitch 2.987E-5 6.977E-3
6.599E-2
2.151E-1
 3 46
31 ctd:C490728 lapatinib CTD 3.188E-5 6.977E-3
6.599E-2
2.296E-1
 3 47
32 CID000001462 AC1L1BJ8 Stitch 3.188E-5 6.977E-3
6.599E-2
2.296E-1
 3 47
33 ctd:C120227 2-(2-chloro-4-iodophenylamino)-N-cyclopropylmethoxy-3,4-difluorobenzamide CTD 3.398E-5 6.977E-3
6.599E-2
2.447E-1
 3 48
34 CID000143560 nitrosyliodide Stitch 3.398E-5 6.977E-3
6.599E-2
2.447E-1
 3 48
35 ctd:C405943 2-(oxalylamino)benzoic acid CTD 3.488E-5 6.977E-3
6.599E-2
2.512E-1
 2 7
36 ctd:C100057 ametryne CTD 3.488E-5 6.977E-3
6.599E-2
2.512E-1
 2 7
37 ctd:C013592 mangiferin CTD 3.655E-5 7.114E-3
6.729E-2
2.632E-1
 4 144
38 ctd:C496492 abrine CTD 3.923E-5 7.315E-3
6.920E-2
2.825E-1
 5 297
39 CID000004752 NSC 523214 Stitch 3.962E-5 7.315E-3
6.920E-2
2.853E-1
 4 147
40 CID000656911 nNOS inhibitor I Stitch 4.080E-5 7.336E-3
6.939E-2
2.938E-1
 3 51
41 ctd:C471405 sorafenib CTD 4.177E-5 7.336E-3
6.939E-2
3.008E-1
 4 149
42 ctd:C452601 sulindac derivative IND 12 CTD 4.647E-5 7.436E-3
7.034E-2
3.346E-1
 2 8
43 ctd:C532657 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one CTD 4.647E-5 7.436E-3
7.034E-2
3.346E-1
 2 8
44 ctd:C000588914 WJ1376-1 CTD 4.647E-5 7.436E-3
7.034E-2
3.346E-1
 2 8
45 ctd:C000588915 WJ1398-1 CTD 4.647E-5 7.436E-3
7.034E-2
3.346E-1
 2 8
46 6817 DN Verteporfin [129497-78-5]; Down 200; 2.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 4.872E-5 7.482E-3
7.077E-2
3.508E-1
 4 155
47 ctd:C028577 monobutyl phthalate CTD 4.883E-5 7.482E-3
7.077E-2
3.517E-1
 5 311
48 ctd:C028009 diallyl disulfide CTD 5.122E-5 7.527E-3
7.120E-2
3.688E-1
 3 55
49 CID000191336 gallin Stitch 5.122E-5 7.527E-3
7.120E-2
3.688E-1
 3 55
50 CID000031745 AC1L1M8Z Stitch 5.969E-5 8.428E-3
7.973E-2
4.299E-1
 2 9
Show 45 more annotations

18: Disease [Display Chart] 29 input genes in category / 1089 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1708349 Hereditary Diffuse Gastric Cancer DisGeNET Curated 5.622E-14 6.122E-11 4.635E-10 6.122E-11 6 14
2 C0232347 No-Reflow Phenomenon DisGeNET Curated 5.153E-9 2.806E-6 2.124E-5 5.612E-6 3 3
3 C0334558 Malignant odontogenic tumor DisGeNET BeFree 3.092E-6 1.123E-3 8.498E-3 3.368E-3 2 2
4 C1302401 Adenoma of large intestine DisGeNET BeFree 5.133E-6 1.397E-3 1.058E-2 5.590E-3 6 256
5 C3549742 Breast cancer, lobular DisGeNET BeFree 7.756E-6 1.682E-3 1.273E-2 8.446E-3 3 22
6 C1879526 Aberrant Crypt Foci DisGeNET Curated 9.267E-6 1.682E-3 1.273E-2 1.009E-2 2 3
7 C1708187 Gardner Fibroma DisGeNET BeFree 1.851E-5 2.880E-3 2.180E-2 2.016E-2 2 4
8 C4024979 Ovarian papillary adenocarcinoma DisGeNET Curated 3.082E-5 3.353E-3 2.538E-2 3.356E-2 2 5
9 C0744333 Gastrointestinal polyps DisGeNET Curated 3.082E-5 3.353E-3 2.538E-2 3.356E-2 2 5
10 C3891448 NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO DisGeNET Curated 3.082E-5 3.353E-3 2.538E-2 3.356E-2 2 5
11 C0920184 Fundic gland polyp DisGeNET BeFree 4.618E-5 3.353E-3 2.538E-2
5.029E-2
 2 6
12 cv:C0919267 Neoplasm of ovary Clinical Variations 4.618E-5 3.353E-3 2.538E-2
5.029E-2
 2 6
13 C0334357 Papillary cystic tumor DisGeNET BeFree 4.618E-5 3.353E-3 2.538E-2
5.029E-2
 2 6
14 C0085661 Onycholysis DisGeNET Curated 4.618E-5 3.353E-3 2.538E-2
5.029E-2
 2 6
15 C0206646 Fibromatosis, Abdominal DisGeNET Curated 4.618E-5 3.353E-3 2.538E-2
5.029E-2
 2 6
16 C0349788 Arrhythmogenic Right Ventricular Dysplasia DisGeNET BeFree 5.247E-5 3.572E-3 2.704E-2
5.714E-2
 3 41
17 C0027746 Nerve Degeneration DisGeNET Curated 5.886E-5 3.701E-3 2.802E-2
6.410E-2
 4 120
18 OMIN:167000 OVARIAN CANCER OMIM 6.458E-5 3.701E-3 2.802E-2
7.033E-2
 2 7
19 C0948209 Intestinal adenocarcinoma DisGeNET BeFree 6.458E-5 3.701E-3 2.802E-2
7.033E-2
 2 7
20 C0750952 Biliary Tract Cancer DisGeNET BeFree 7.801E-5 4.248E-3 3.216E-2
8.496E-2
 4 129
21 OMIN:155255 MEDULLOBLASTOMA; MDB OMIM 8.601E-5 4.455E-3 3.373E-2
9.366E-2
 2 8
22 cv:C2239176 Hepatocellular carcinoma Clinical Variations 1.105E-4 4.455E-3 3.373E-2
1.203E-1
 2 9
23 C0152426 Craniorachischisis DisGeNET Curated 1.105E-4 4.455E-3 3.373E-2
1.203E-1
 2 9
24 C1861901 Subacute progressive viral hepatitis DisGeNET Curated 1.105E-4 4.455E-3 3.373E-2
1.203E-1
 2 9
25 C0206711 Pilomatrixoma DisGeNET Curated 1.105E-4 4.455E-3 3.373E-2
1.203E-1
 2 9
26 OMIN:114550 HEPATOCELLULAR CARCINOMA OMIM 1.105E-4 4.455E-3 3.373E-2
1.203E-1
 2 9
27 C2063326 Cardiomyopathy, right ventricular DisGeNET Curated 1.105E-4 4.455E-3 3.373E-2
1.203E-1
 2 9
28 C4021664 Abnormality of the abdominal wall DisGeNET Curated 1.379E-4 5.364E-3 4.061E-2
1.502E-1
 2 10
29 C0016048 Fibromatosis DisGeNET BeFree 1.684E-4 6.002E-3 4.544E-2
1.834E-1
 2 11
30 C1842680 Hypoplastic lobules DisGeNET Curated 1.684E-4 6.002E-3 4.544E-2
1.834E-1
 2 11
31 C0027794 Neural Tube Defects DisGeNET Curated 1.709E-4 6.002E-3 4.544E-2
1.861E-1
 4 158
32 OMIN:137215 GASTRIC CANCER OMIM 2.018E-4 6.869E-3
5.200E-2
2.198E-1
 2 12
33 C0279672 Cervical Adenocarcinoma DisGeNET BeFree 2.089E-4 6.894E-3
5.219E-2
2.275E-1
 3 65
34 C0349579 Atypical Endometrial Hyperplasia DisGeNET BeFree 2.383E-4 7.414E-3
5.613E-2
2.595E-1
 2 13
35 C0267812 Micronodular cirrhosis DisGeNET Curated 2.383E-4 7.414E-3
5.613E-2
2.595E-1
 2 13
36 C0345967 Malignant mesothelioma DisGeNET Curated 2.737E-4 8.279E-3
6.268E-2
2.981E-1
 5 331
37 C1851841 ECTRODACTYLY, ECTODERMAL DYSPLASIA, AND CLEFT LIP/PALATE SYNDROME 1 DisGeNET Curated 3.191E-4 9.172E-3
6.944E-2
3.475E-1
 3 75
38 C0700636 Focal nodular hyperplasia of liver DisGeNET BeFree 3.200E-4 9.172E-3
6.944E-2
3.485E-1
 2 15
39 C4021745 Abnormality of the musculature DisGeNET Curated 3.654E-4 1.020E-2
7.723E-2
3.979E-1
 2 16
40 C0025500 Mesothelioma DisGeNET Curated 3.876E-4 1.055E-2
7.990E-2
4.221E-1
 5 357
41 C0231528 Myalgia DisGeNET Curated 4.003E-4 1.063E-2
8.049E-2
4.359E-1
 3 81
42 C1449563 Cardiomyopathy, Familial Idiopathic DisGeNET Curated 4.290E-4 1.112E-2
8.422E-2
4.672E-1
 5 365
43 C0334287 Fibrolamellar hepatocellular carcinoma DisGeNET Curated 5.189E-4 1.284E-2
9.723E-2
5.651E-1
 2 19
44 C1257915 Intestinal Polyposis DisGeNET Curated 5.189E-4 1.284E-2
9.723E-2
5.651E-1
 2 19
45 C0334092 Hamartomatous polyp DisGeNET Curated 5.759E-4 1.343E-2
1.017E-1
6.272E-1
 2 20
46 C0861352 Lobular Neoplasia DisGeNET BeFree 5.759E-4 1.343E-2
1.017E-1
6.272E-1
 2 20
47 C0028880 Odontogenic Tumors DisGeNET BeFree 6.358E-4 1.343E-2
1.017E-1
6.924E-1
 2 21
48 C0030186 Paget Disease Extramammary DisGeNET BeFree 6.358E-4 1.343E-2
1.017E-1
6.924E-1
 2 21
49 C4020813 Increased gastric cancer DisGeNET Curated 6.358E-4 1.343E-2
1.017E-1
6.924E-1
 2 21
50 C2919828 Chronic ulcerative colitis DisGeNET BeFree 6.358E-4 1.343E-2
1.017E-1
6.924E-1
 2 21
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