|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
16033648
|
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
|
Pubmed
|
3.870E-16
|
3.913E-13
|
2.933E-12
|
3.913E-13
|
8
|
285
|
|
2
|
9433137
|
STAR, a gene family involved in signal transduction and activation of RNA.
|
Pubmed
|
1.292E-11
|
6.533E-9
|
4.898E-8
|
1.307E-8
|
3
|
3
|
|
3
|
12529443
|
Sam68 RNA binding protein is an in vivo substrate for protein arginine N-methyltransferase 1.
|
Pubmed
|
2.584E-10
|
8.708E-8
|
6.528E-7
|
2.612E-7
|
3
|
6
|
|
4
|
28977470
|
The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.
|
Pubmed
|
4.344E-8
|
5.671E-6
|
4.251E-5
|
4.392E-5
|
4
|
147
|
|
5
|
9315629
|
Self-association of the single-KH-domain family members Sam68, GRP33, GLD-1, and Qk1: role of the KH domain.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
6
|
11735223
|
Comparative genomic sequence analysis of the FXR gene family: FMR1, FXR1, and FXR2.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
7
|
10564820
|
Salpalpha and Salpbeta, growth-arresting homologs of Sam68.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
8
|
26758068
|
Structural basis of RNA recognition and dimerization by the STAR proteins T-STAR and Sam68.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
9
|
21072162
|
Structural studies of the tandem Tudor domains of fragile X mental retardation related proteins FXR1 and FXR2.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
10
|
9259278
|
Differential expression of FMR1, FXR1 and FXR2 proteins in human brain and testis.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
11
|
10196376
|
Different targets for the fragile X-related proteins revealed by their distinct nuclear localizations.
|
Pubmed
|
6.170E-8
|
5.671E-6
|
4.251E-5
|
6.238E-5
|
2
|
2
|
|
12
|
22365833
|
Dynamic protein-protein interaction wiring of the human spliceosome.
|
Pubmed
|
1.407E-7
|
6.683E-6
|
5.009E-5
|
1.423E-4
|
4
|
197
|
|
13
|
25496916
|
A HIV-1 Tat mutant protein disrupts HIV-1 Rev function by targeting the DEAD-box RNA helicase DDX1.
|
Pubmed
|
1.823E-7
|
6.683E-6
|
5.009E-5
|
1.843E-4
|
3
|
45
|
|
14
|
28767039
|
FXR1 regulates transcription and is required for growth of human cancer cells with
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
15
|
27770568
|
Sub-synaptic, multiplexed analysis of proteins reveals Fragile X related protein 2 is mislocalized in
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
16
|
21957233
|
FXR1P but not FMRP regulates the levels of mammalian brain-specific microRNA-9 and microRNA-124.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
17
|
19254361
|
Inhibition of HIV-1 gene expression by Sam68 Delta C: multiple targets but a common mechanism?
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
18
|
8668200
|
Specific sequences in the fragile X syndrome protein FMR1 and the FXR proteins mediate their binding to 60S ribosomal subunits and the interactions among them.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
19
|
20442204
|
Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
20
|
7489725
|
The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
21
|
18589395
|
Fragile X-related proteins regulate mammalian circadian behavioral rhythms.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
22
|
28204491
|
Fragile X related protein 1 (FXR1P) regulates proliferation of adult neural stem cells.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
23
|
16474851
|
The tumour-suppressor protein ASPP1 is nuclear in human germ cells and can modulate ratios of CD44 exon V5 spliced isoforms in vivo.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
24
|
19487368
|
Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
25
|
26612855
|
Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
26
|
11157796
|
Evidence that fragile X mental retardation protein is a negative regulator of translation.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
27
|
19091369
|
Mapping of determinants involved in the stimulation of HIV-1 expression by Sam68.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
28
|
10888599
|
The fragile X-related proteins FXR1P and FXR2P contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins.
|
Pubmed
|
1.851E-7
|
6.683E-6
|
5.009E-5
|
1.871E-4
|
2
|
3
|
|
29
|
16571602
|
The nuclear microspherule protein 58 is a novel RNA-binding protein that interacts with fragile X mental retardation protein in polyribosomal mRNPs from neurons.
|
Pubmed
|
3.701E-7
|
1.100E-5
|
8.250E-5
|
3.742E-4
|
2
|
4
|
|
30
|
15471878
|
The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.
|
Pubmed
|
3.701E-7
|
1.100E-5
|
8.250E-5
|
3.742E-4
|
2
|
4
|
|
31
|
18664458
|
Tdrd3 is a novel stress granule-associated protein interacting with the Fragile-X syndrome protein FMRP.
|
Pubmed
|
3.701E-7
|
1.100E-5
|
8.250E-5
|
3.742E-4
|
2
|
4
|
|
32
|
10567518
|
Isolation of an FMRP-associated messenger ribonucleoprotein particle and identification of nucleolin and the fragile X-related proteins as components of the complex.
|
Pubmed
|
3.701E-7
|
1.100E-5
|
8.250E-5
|
3.742E-4
|
2
|
4
|
|
33
|
10556305
|
A novel RNA-binding nuclear protein that interacts with the fragile X mental retardation (FMR1) protein.
|
Pubmed
|
3.701E-7
|
1.100E-5
|
8.250E-5
|
3.742E-4
|
2
|
4
|
|
34
|
22196734
|
SAM68 regulates neuronal activity-dependent alternative splicing of neurexin-1.
|
Pubmed
|
3.701E-7
|
1.100E-5
|
8.250E-5
|
3.742E-4
|
2
|
4
|
|
35
|
10077576
|
Characterization of Sam68-like mammalian proteins SLM-1 and SLM-2: SLM-1 is a Src substrate during mitosis.
|
Pubmed
|
6.167E-7
|
1.782E-5
|
1.335E-4
|
6.235E-4
|
2
|
5
|
|
36
|
26777405
|
ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.
|
Pubmed
|
9.168E-7
|
2.398E-5
|
1.798E-4
|
9.269E-4
|
4
|
315
|
|
37
|
18321792
|
Dynamic expression of the RNA-binding protein Sam68 during mouse pre-implantation development.
|
Pubmed
|
9.250E-7
|
2.398E-5
|
1.798E-4
|
9.352E-4
|
2
|
6
|
|
38
|
11438699
|
A highly conserved protein family interacting with the fragile X mental retardation protein (FMRP) and displaying selective interactions with FMRP-related proteins FXR1P and FXR2P.
|
Pubmed
|
9.250E-7
|
2.398E-5
|
1.798E-4
|
9.352E-4
|
2
|
6
|
|
39
|
25145264
|
Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1.
|
Pubmed
|
9.250E-7
|
2.398E-5
|
1.798E-4
|
9.352E-4
|
2
|
6
|
|
40
|
8871564
|
The mouse poly(C)-binding protein exists in multiple isoforms and interacts with several RNA-binding proteins.
|
Pubmed
|
1.295E-6
|
3.193E-5
|
2.393E-4
|
1.309E-3
|
2
|
7
|
|
41
|
11118435
|
The STAR/GSG family protein rSLM-2 regulates the selection of alternative splice sites.
|
Pubmed
|
1.295E-6
|
3.193E-5
|
2.393E-4
|
1.309E-3
|
2
|
7
|
|
42
|
24778252
|
TRIM65 regulates microRNA activity by ubiquitination of TNRC6.
|
Pubmed
|
1.629E-6
|
3.921E-5
|
2.939E-4
|
1.647E-3
|
4
|
364
|
|
43
|
23974796
|
Identification of a long non-coding RNA-associated RNP complex regulating metastasis at the translational step.
|
Pubmed
|
1.726E-6
|
4.058E-5
|
3.042E-4
|
1.745E-3
|
2
|
8
|
|
44
|
17643375
|
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
|
Pubmed
|
2.142E-6
|
4.921E-5
|
3.689E-4
|
2.165E-3
|
4
|
390
|
|
45
|
10332027
|
T-STAR/ETOILE: a novel relative of SAM68 that interacts with an RNA-binding protein implicated in spermatogenesis.
|
Pubmed
|
2.773E-6
|
6.231E-5
|
4.671E-4
|
2.804E-3
|
2
|
10
|
|
46
|
22022532
|
Fragile X related protein 1 clusters with ribosomes and messenger RNAs at a subset of dendritic spines in the mouse hippocampus.
|
Pubmed
|
3.389E-6
|
7.290E-5
|
5.465E-4
|
3.427E-3
|
2
|
11
|
|
47
|
29142209
|
Fbxo4-mediated degradation of Fxr1 suppresses tumorigenesis in head and neck squamous cell carcinoma.
|
Pubmed
|
3.389E-6
|
7.290E-5
|
5.465E-4
|
3.427E-3
|
2
|
11
|
|
48
|
10749975
|
RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing.
|
Pubmed
|
4.805E-6
|
1.012E-4
|
7.587E-4
|
4.858E-3
|
2
|
13
|
|
49
|
23979707
|
SILAC-based proteomics of human primary endothelial cell morphogenesis unveils tumor angiogenic markers.
|
Pubmed
|
1.071E-5
|
2.209E-4
|
1.656E-3
|
1.082E-2
|
3
|
173
|
|
50
|
20975687
|
TERRA transcripts are bound by a complex array of RNA-binding proteins.
|
Pubmed
|
1.698E-5
|
3.433E-4
|
2.573E-3
|
1.716E-2
|
2
|
24
|