Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc118_6, positive side

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1: GO: Molecular Function [Display Chart] 6 input genes in category / 18 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0003887 DNA-directed DNA polymerase activity 3.245E-5 5.840E-4 2.041E-3 5.840E-4 2 28
2 GO:0034061 DNA polymerase activity 9.253E-5 8.328E-4 2.911E-3 1.666E-3 2 47
3 GO:0016779 nucleotidyltransferase activity 7.312E-4 4.387E-3 1.533E-2 1.316E-2 2 132
4 GO:0042393 histone binding 1.353E-3 6.089E-3 2.128E-2 2.435E-2 2 180
5 GO:0033170 protein-DNA loading ATPase activity 2.891E-3 8.672E-3 3.031E-2
5.203E-2
1 9
6 GO:0003689 DNA clamp loader activity 2.891E-3 8.672E-3 3.031E-2
5.203E-2
1 9
7 GO:0070577 lysine-acetylated histone binding 5.454E-3 1.371E-2 4.793E-2
9.818E-2
1 17
8 GO:0035173 histone kinase activity 6.094E-3 1.371E-2 4.793E-2
1.097E-1
1 19
9 GO:0016887 ATPase activity 8.021E-3 1.604E-2
5.607E-2
1.444E-1
2 446
10 GO:0030546 receptor activator activity 1.120E-2 2.016E-2
7.048E-2
2.016E-1
1 35
11 GO:0031491 nucleosome binding 1.438E-2 2.205E-2
7.707E-2
2.589E-1
1 45
12 GO:0004715 non-membrane spanning protein tyrosine kinase activity 1.470E-2 2.205E-2
7.707E-2
2.646E-1
1 46
13 GO:0030545 receptor regulator activity 1.629E-2 2.255E-2
7.883E-2
2.932E-1
1 51
14 GO:0008094 DNA-dependent ATPase activity 2.954E-2 3.797E-2
1.327E-1
5.316E-1
1 93
Show 9 more annotations

2: GO: Biological Process [Display Chart] 6 input genes in category / 94 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006338 chromatin remodeling 1.315E-5 1.236E-3 6.337E-3 1.236E-3 3 164
2 GO:0006260 DNA replication 1.220E-4 5.394E-3 2.765E-2 1.147E-2 3 346
3 GO:0016570 histone modification 2.603E-4 5.394E-3 2.765E-2 2.447E-2 3 447
4 GO:0045815 positive regulation of gene expression, epigenetic 2.771E-4 5.394E-3 2.765E-2 2.605E-2 2 81
5 GO:0016569 covalent chromatin modification 2.869E-4 5.394E-3 2.765E-2 2.697E-2 3 462
6 GO:0006333 chromatin assembly or disassembly 1.481E-3 2.159E-2
1.107E-1
1.392E-1
2 188
7 GO:0006302 double-strand break repair 1.608E-3 2.159E-2
1.107E-1
1.511E-1
2 196
8 GO:0071897 DNA biosynthetic process 1.860E-3 2.185E-2
1.120E-1
1.748E-1
2 211
9 GO:0016584 nucleosome positioning 2.575E-3 2.689E-2
1.379E-1
2.421E-1
1 8
10 GO:0040029 regulation of gene expression, epigenetic 2.914E-3 2.739E-2
1.404E-1
2.739E-1
2 265
11 GO:0048096 chromatin-mediated maintenance of transcription 3.539E-3 3.024E-2
1.550E-1
3.327E-1
1 11
12 GO:0043374 CD8-positive, alpha-beta T cell differentiation 3.860E-3 3.024E-2
1.550E-1
3.629E-1
1 12
13 GO:0000076 DNA replication checkpoint 5.145E-3 3.720E-2
1.907E-1
4.836E-1
1 16
14 GO:0042276 error-prone translesion synthesis 6.107E-3 4.100E-2
2.102E-1
5.740E-1
1 19
15 GO:0036037 CD8-positive, alpha-beta T cell activation 6.748E-3 4.229E-2
2.167E-1
6.343E-1
1 21
16 GO:0060004 reflex 7.709E-3 4.529E-2
2.321E-1
7.246E-1
1 24
17 GO:0000722 telomere maintenance via recombination 1.091E-2 4.951E-2
2.538E-1
1.000E0
1 34
18 GO:0006270 DNA replication initiation 1.123E-2 4.951E-2
2.538E-1
1.000E0
1 35
19 GO:0016572 histone phosphorylation 1.186E-2 4.951E-2
2.538E-1
1.000E0
1 37
20 GO:0000183 chromatin silencing at rDNA 1.314E-2 4.951E-2
2.538E-1
1.000E0
1 41
21 GO:0019985 translesion synthesis 1.314E-2 4.951E-2
2.538E-1
1.000E0
1 41
22 GO:0034080 CENP-A containing nucleosome assembly 1.346E-2 4.951E-2
2.538E-1
1.000E0
1 42
23 GO:0061641 CENP-A containing chromatin organization 1.346E-2 4.951E-2
2.538E-1
1.000E0
1 42
24 GO:0006312 mitotic recombination 1.441E-2 4.951E-2
2.538E-1
1.000E0
1 45
25 GO:0031055 chromatin remodeling at centromere 1.473E-2 4.951E-2
2.538E-1
1.000E0
1 46
26 GO:2000273 positive regulation of signaling receptor activity 1.473E-2 4.951E-2
2.538E-1
1.000E0
1 46
27 GO:0006921 cellular component disassembly involved in execution phase of apoptosis 1.600E-2 4.951E-2
2.538E-1
1.000E0
1 50
28 GO:0034724 DNA replication-independent nucleosome organization 1.696E-2 4.951E-2
2.538E-1
1.000E0
1 53
29 GO:0006336 DNA replication-independent nucleosome assembly 1.696E-2 4.951E-2
2.538E-1
1.000E0
1 53
30 GO:0034508 centromere complex assembly 1.696E-2 4.951E-2
2.538E-1
1.000E0
1 53
31 GO:0043486 histone exchange 1.727E-2 4.951E-2
2.538E-1
1.000E0
1 54
32 GO:0006301 postreplication repair 1.727E-2 4.951E-2
2.538E-1
1.000E0
1 54
33 GO:0008156 negative regulation of DNA replication 1.791E-2 4.951E-2
2.538E-1
1.000E0
1 56
34 GO:0050798 activated T cell proliferation 1.791E-2 4.951E-2
2.538E-1
1.000E0
1 56
Show 29 more annotations

3: GO: Cellular Component [Display Chart] 6 input genes in category / 33 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043596 nuclear replication fork 2.754E-10 9.089E-9 3.716E-8 9.089E-9 4 41
2 GO:0005657 replication fork 2.080E-9 3.432E-8 1.403E-7 6.864E-8 4 67
3 GO:0008622 epsilon DNA polymerase complex 8.254E-7 9.080E-6 3.712E-5 2.724E-5 2 5
4 GO:0042575 DNA polymerase complex 7.502E-6 4.951E-5 2.024E-4 2.476E-4 2 14
5 GO:0000109 nucleotide-excision repair complex 7.502E-6 4.951E-5 2.024E-4 2.476E-4 2 14
6 GO:0043601 nuclear replisome 3.110E-5 1.711E-4 6.994E-4 1.026E-3 2 28
7 GO:0030894 replisome 3.824E-5 1.803E-4 7.371E-4 1.262E-3 2 31
8 GO:1990391 DNA repair complex 8.494E-5 3.504E-4 1.433E-3 2.803E-3 2 46
9 GO:0000792 heterochromatin 3.053E-4 1.039E-3 4.247E-3 1.007E-2 2 87
10 GO:0031389 Rad17 RFC-like complex 3.148E-4 1.039E-3 4.247E-3 1.039E-2 1 1
11 GO:0031213 RSF complex 6.295E-4 1.888E-3 7.721E-3 2.077E-2 1 2
12 GO:0032993 protein-DNA complex 1.341E-3 3.687E-3 1.507E-2 4.424E-2 2 183
13 GO:0000793 condensed chromosome 1.727E-3 4.384E-3 1.793E-2
5.699E-2
2 208
14 GO:0016589 NURF complex 1.887E-3 4.449E-3 1.819E-2
6.229E-2
1 6
15 GO:0061695 transferase complex, transferring phosphorus-containing groups 2.366E-3 5.206E-3 2.129E-2
7.809E-2
2 244
16 GO:0005677 chromatin silencing complex 2.830E-3 5.837E-3 2.387E-2
9.339E-2
1 9
17 GO:0031010 ISWI-type complex 3.144E-3 6.103E-3 2.495E-2
1.038E-1
1 10
18 GO:0098687 chromosomal region 4.643E-3 8.512E-3 3.481E-2
1.532E-1
2 344
19 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex 5.027E-3 8.730E-3 3.570E-2
1.659E-1
1 16
20 GO:0005721 pericentric heterochromatin 5.967E-3 9.845E-3 4.025E-2
1.969E-1
1 19
21 GO:0000785 chromatin 9.128E-3 1.434E-2
5.865E-2
3.012E-1
2 487
22 GO:0005720 nuclear heterochromatin 1.315E-2 1.972E-2
8.065E-2
4.339E-1
1 42
23 GO:0070603 SWI/SNF superfamily-type complex 2.307E-2 3.310E-2
1.354E-1
7.614E-1
1 74
24 GO:0000123 histone acetyltransferase complex 2.769E-2 3.798E-2
1.553E-1
9.139E-1
1 89
25 GO:0016605 PML body 3.077E-2 3.798E-2
1.553E-1
1.000E0
1 99
26 GO:0031248 protein acetyltransferase complex 3.107E-2 3.798E-2
1.553E-1
1.000E0
1 100
27 GO:1902493 acetyltransferase complex 3.107E-2 3.798E-2
1.553E-1
1.000E0
1 100
28 GO:0016363 nuclear matrix 3.260E-2 3.843E-2
1.571E-1
1.000E0
1 105
29 GO:0034399 nuclear periphery 4.176E-2 4.751E-2
1.943E-1
1.000E0
1 135
Show 24 more annotations

4: Human Phenotype [Display Chart] 1 input genes in category / 485 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 4 input genes in category / 128 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0012120 trophectoderm cell degeneration 7.725E-4 3.296E-2
1.791E-1
9.888E-2
1 2
2 MP:0030134 small fourth pharyngeal arch 7.725E-4 3.296E-2
1.791E-1
9.888E-2
1 2
3 MP:0013270 fourth pharyngeal arch hypoplasia 7.725E-4 3.296E-2
1.791E-1
9.888E-2
1 2
4 MP:0002884 abnormal pharyngeal arch morphology 1.781E-3 4.323E-2
2.349E-1
2.280E-1
2 181
5 MP:0012119 increased trophectoderm apoptosis 1.930E-3 4.323E-2
2.349E-1
2.471E-1
1 5
6 MP:0000421 mottled coat 2.702E-3 4.323E-2
2.349E-1
3.458E-1
1 7
7 MP:0006411 upturned snout 2.702E-3 4.323E-2
2.349E-1
3.458E-1
1 7
8 MP:0030049 prominent forehead 2.702E-3 4.323E-2
2.349E-1
3.458E-1
1 7
Show 3 more annotations

6: Domain [Display Chart] 6 input genes in category / 83 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF12213 Dpoe2NT Pfam 3.203E-4 3.127E-3 1.564E-2 2.658E-2 1 1
2 IPR018324 Rad17/Rad24 fun/met InterPro 3.203E-4 3.127E-3 1.564E-2 2.658E-2 1 1
3 IPR024639 DNA pol e bsu N InterPro 3.203E-4 3.127E-3 1.564E-2 2.658E-2 1 1
4 IPR016266 DNA pol e bsu InterPro 3.203E-4 3.127E-3 1.564E-2 2.658E-2 1 1
5 IPR004582 Checkpoint prot Rad17 Rad24 InterPro 3.203E-4 3.127E-3 1.564E-2 2.658E-2 1 1
6 PF09110 HAND Pfam 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
7 IPR015194 ISWI HAND-dom InterPro 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
8 IPR015195 SLIDE InterPro 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
9 PF10537 WAC Acf1 DNA bd Pfam 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
10 PF09111 SLIDE Pfam 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
11 IPR013136 WSTF Acf1 Cbp146 InterPro 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
12 PS51136 WAC PROSITE 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
13 PF16557 CUTL Pfam 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
14 IPR029915 ISWI InterPro 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
15 IPR032392 ULD InterPro 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
16 IPR032355 CUTL InterPro 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
17 PF16534 ULD Pfam 6.404E-4 3.127E-3 1.564E-2
5.316E-2
1 2
18 PF13892 DBINO Pfam 9.605E-4 3.796E-3 1.899E-2
7.972E-2
1 3
19 IPR007185 DNA pol alpha/epsilon bsu InterPro 9.605E-4 3.796E-3 1.899E-2
7.972E-2
1 3
20 IPR020838 DBINO InterPro 9.605E-4 3.796E-3 1.899E-2
7.972E-2
1 3
21 PF04042 DNA pol E B Pfam 9.605E-4 3.796E-3 1.899E-2
7.972E-2
1 3
22 PF15613 WSD Pfam 1.600E-3 4.920E-3 2.461E-2
1.328E-1
1 5
23 PF15612 WHIM1 Pfam 1.600E-3 4.920E-3 2.461E-2
1.328E-1
1 5
24 IPR028942 WHIM1 dom InterPro 1.600E-3 4.920E-3 2.461E-2
1.328E-1
1 5
25 SM00571 DDT SMART 1.600E-3 4.920E-3 2.461E-2
1.328E-1
1 5
26 IPR018501 DDT dom InterPro 1.600E-3 4.920E-3 2.461E-2
1.328E-1
1 5
27 IPR028941 WHIM2 dom InterPro 1.600E-3 4.920E-3 2.461E-2
1.328E-1
1 5
28 PS50827 DDT PROSITE 1.920E-3 5.692E-3 2.847E-2
1.594E-1
1 6
29 IPR003350 CUT dom InterPro 2.240E-3 5.810E-3 2.906E-2
1.859E-1
1 7
30 PF02376 CUT Pfam 2.240E-3 5.810E-3 2.906E-2
1.859E-1
1 7
31 PS51042 CUT PROSITE 2.240E-3 5.810E-3 2.906E-2
1.859E-1
1 7
32 SM01109 CUT SMART 2.240E-3 5.810E-3 2.906E-2
1.859E-1
1 7
33 PF00808 CBFD NFYB HMF Pfam 2.560E-3 6.249E-3 3.126E-2
2.125E-1
1 8
34 IPR003958 CBFA NFYB domain InterPro 2.560E-3 6.249E-3 3.126E-2
2.125E-1
1 8
35 1.10.10.60 - Gene3D 3.277E-3 7.770E-3 3.887E-2
2.720E-1
2 283
36 IPR009057 Homeodomain-like InterPro 4.480E-3 1.033E-2
5.167E-2
3.719E-1
2 332
37 IPR018359 Bromodomain CS InterPro 8.299E-3 1.813E-2
9.067E-2
6.888E-1
1 26
38 IPR017884 SANT dom InterPro 8.299E-3 1.813E-2
9.067E-2
6.888E-1
1 26
39 1.10.260.40 - Gene3D 8.617E-3 1.834E-2
9.173E-2
7.152E-1
1 27
40 PS51293 SANT PROSITE 8.935E-3 1.854E-2
9.274E-2
7.416E-1
1 28
41 IPR010982 Lambda DNA-bd dom InterPro 9.253E-3 1.873E-2
9.370E-2
7.680E-1
1 29
42 IPR000330 SNF2 N InterPro 1.021E-2 1.970E-2
9.854E-2
8.471E-1
1 32
43 PF00176 SNF2 N Pfam 1.021E-2 1.970E-2
9.854E-2
8.471E-1
1 32
44 IPR002464 DNA/RNA helicase DEAH CS InterPro 1.116E-2 2.051E-2
1.026E-1
9.261E-1
1 35
45 PF00249 Myb DNA-binding Pfam 1.116E-2 2.051E-2
1.026E-1
9.261E-1
1 35
46 PS00633 BROMODOMAIN 1 PROSITE 1.179E-2 2.051E-2
1.026E-1
9.788E-1
1 37
47 PS50090 MYB LIKE PROSITE 1.211E-2 2.051E-2
1.026E-1
1.000E0
1 38
48 PS00690 DEAH ATP HELICASE PROSITE 1.211E-2 2.051E-2
1.026E-1
1.000E0
1 38
49 PF00439 Bromodomain Pfam 1.211E-2 2.051E-2
1.026E-1
1.000E0
1 38
50 PS50014 BROMODOMAIN 2 PROSITE 1.306E-2 2.095E-2
1.048E-1
1.000E0
1 41
Show 45 more annotations

7: Pathway [Display Chart] 6 input genes in category / 67 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1309095 DNA Double-Strand Break Repair BioSystems: REACTOME 2.578E-9 1.728E-7 8.274E-7 1.728E-7 5 169
2 1270350 DNA Repair BioSystems: REACTOME 6.291E-8 2.107E-6 1.009E-5 4.215E-6 5 319
3 1309102 HDR through Homologous Recombination (HRR) BioSystems: REACTOME 3.220E-6 7.192E-5 3.444E-4 2.157E-4 3 69
4 1269860 Telomere C-strand synthesis initiation BioSystems: REACTOME 5.413E-6 7.253E-5 3.474E-4 3.627E-4 2 8
5 1269780 DNA replication initiation BioSystems: REACTOME 5.413E-6 7.253E-5 3.474E-4 3.627E-4 2 8
6 1269853 Chromosome Maintenance BioSystems: REACTOME 1.317E-5 1.470E-4 7.041E-4 8.821E-4 3 110
7 1309100 HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) BioSystems: REACTOME 2.381E-5 2.274E-4 1.089E-3 1.596E-3 3 134
8 1309099 Homology Directed Repair BioSystems: REACTOME 2.716E-5 2.274E-4 1.089E-3 1.819E-3 3 140
9 1270366 PCNA-Dependent Long Patch Base Excision Repair BioSystems: REACTOME 4.048E-5 3.014E-4 1.443E-3 2.712E-3 2 21
10 1269859 Telomere C-strand (Lagging Strand) Synthesis BioSystems: REACTOME 5.317E-5 3.226E-4 1.545E-3 3.562E-3 2 24
11 1270364 Resolution of AP sites via the multiple-nucleotide patch replacement pathway BioSystems: REACTOME 5.317E-5 3.226E-4 1.545E-3 3.562E-3 2 24
12 1309116 Gap-filling DNA repair synthesis and ligation in GG-NER BioSystems: REACTOME 5.778E-5 3.226E-4 1.545E-3 3.871E-3 2 25
13 1270368 Recognition of DNA damage by PCNA-containing replication complex BioSystems: REACTOME 8.370E-5 4.250E-4 2.036E-3 5.608E-3 2 30
14 1269857 Extension of Telomeres BioSystems: REACTOME 8.945E-5 4.250E-4 2.036E-3 5.993E-3 2 31
15 1269773 Activation of the pre-replicative complex BioSystems: REACTOME 9.539E-5 4.250E-4 2.036E-3 6.391E-3 2 32
16 83043 Base excision repair BioSystems: KEGG 1.015E-4 4.250E-4 2.036E-3 6.802E-3 2 33
17 1270374 Termination of translesion DNA synthesis BioSystems: REACTOME 1.078E-4 4.250E-4 2.036E-3 7.226E-3 2 34
18 83039 DNA replication BioSystems: KEGG 1.211E-4 4.286E-4 2.053E-3 8.111E-3 2 36
19 1270359 Resolution of Abasic Sites (AP sites) BioSystems: REACTOME 1.279E-4 4.286E-4 2.053E-3 8.573E-3 2 37
20 1270351 Base Excision Repair BioSystems: REACTOME 1.279E-4 4.286E-4 2.053E-3 8.573E-3 2 37
21 1309115 Dual Incision in GG-NER BioSystems: REACTOME 1.574E-4 4.793E-4 2.296E-3 1.055E-2 2 41
22 1270369 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template BioSystems: REACTOME 1.574E-4 4.793E-4 2.296E-3 1.055E-2 2 41
23 83044 Nucleotide excision repair BioSystems: KEGG 2.072E-4 6.037E-4 2.891E-3 1.388E-2 2 47
24 1270367 DNA Damage Bypass BioSystems: REACTOME 2.347E-4 6.552E-4 3.138E-3 1.572E-2 2 50
25 1309120 Gap-filling DNA repair synthesis and ligation in TC-NER BioSystems: REACTOME 3.972E-4 1.055E-3 5.054E-3 2.661E-2 2 65
26 1309119 Dual incision in TC-NER BioSystems: REACTOME 4.095E-4 1.055E-3 5.054E-3 2.744E-2 2 66
27 1309098 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks BioSystems: REACTOME 5.430E-4 1.334E-3 6.387E-3 3.638E-2 2 76
28 1309096 DNA Double Strand Break Response BioSystems: REACTOME 5.573E-4 1.334E-3 6.387E-3 3.734E-2 2 77
29 1309117 Transcription-Coupled Nucleotide Excision Repair (TC-NER) BioSystems: REACTOME 5.866E-4 1.355E-3 6.491E-3 3.930E-2 2 79
30 1269856 Telomere Maintenance BioSystems: REACTOME 6.473E-4 1.446E-3 6.924E-3 4.337E-2 2 83
31 1309112 Global Genome Nucleotide Excision Repair (GG-NER) BioSystems: REACTOME 6.788E-4 1.467E-3 7.027E-3 4.548E-2 2 85
32 1269831 M/G1 Transition BioSystems: REACTOME 7.274E-4 1.477E-3 7.073E-3 4.874E-2 2 88
33 1269832 DNA Replication Pre-Initiation BioSystems: REACTOME 7.274E-4 1.477E-3 7.073E-3 4.874E-2 2 88
34 1339126 B-WICH complex positively regulates rRNA expression BioSystems: REACTOME 8.295E-4 1.635E-3 7.829E-3
5.558E-2
2 94
35 1269779 Synthesis of DNA BioSystems: REACTOME 9.950E-4 1.905E-3 9.122E-3
6.666E-2
2 103
36 82946 Pyrimidine metabolism BioSystems: KEGG 1.034E-3 1.924E-3 9.214E-3
6.926E-2
2 105
37 1339125 Positive epigenetic regulation of rRNA expression BioSystems: REACTOME 1.113E-3 2.016E-3 9.656E-3
7.460E-2
2 109
38 1269875 DNA Replication BioSystems: REACTOME 1.154E-3 2.019E-3 9.669E-3
7.734E-2
2 111
39 1309111 Nucleotide Excision Repair BioSystems: REACTOME 1.175E-3 2.019E-3 9.669E-3
7.873E-2
2 112
40 1269768 G1/S Transition BioSystems: REACTOME 1.370E-3 2.294E-3 1.099E-2
9.178E-2
2 121
41 1269777 S Phase BioSystems: REACTOME 1.627E-3 2.660E-3 1.274E-2
1.090E-1
2 132
42 1269764 Mitotic G1-G1/S phases BioSystems: REACTOME 1.960E-3 3.126E-3 1.497E-2
1.313E-1
2 145
43 1269734 Epigenetic regulation of gene expression BioSystems: REACTOME 2.151E-3 3.351E-3 1.605E-2
1.441E-1
2 152
44 82944 Purine metabolism BioSystems: KEGG 2.839E-3 4.324E-3 2.071E-2
1.902E-1
2 175
45 373901 HTLV-I infection BioSystems: KEGG 5.982E-3 8.906E-3 4.266E-2
4.008E-1
2 256
46 M9703 Role of BRCA1, BRCA2 and ATR in Cancer Susceptibility MSigDB C2 BIOCARTA (v6.0) 1.008E-2 1.468E-2
7.032E-2
6.754E-1
1 21
47 1269757 Activation of ATR in response to replication stress BioSystems: REACTOME 1.770E-2 2.524E-2
1.209E-1
1.000E0
1 37
48 1309108 HDR through Single Strand Annealing (SSA) BioSystems: REACTOME 1.818E-2 2.537E-2
1.215E-1
1.000E0
1 38
49 1270288 Apoptotic cleavage of cellular proteins BioSystems: REACTOME 1.865E-2 2.550E-2
1.221E-1
1.000E0
1 39
50 1309104 Presynaptic phase of homologous DNA pairing and strand exchange BioSystems: REACTOME 1.913E-2 2.563E-2
1.228E-1
1.000E0
1 40
Show 45 more annotations

8: Pubmed [Display Chart] 6 input genes in category / 463 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 14500819 The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. Pubmed 2.154E-11 9.972E-9 6.697E-8 9.972E-9 3 5
2 19092802 WSTF regulates the H2A.X DNA damage response via a novel tyrosine kinase activity. Pubmed 6.170E-8 7.141E-6 4.796E-5 2.857E-5 2 3
3 15543136 The Williams syndrome transcription factor interacts with PCNA to target chromatin remodelling by ISWI to replication foci. Pubmed 6.170E-8 7.141E-6 4.796E-5 2.857E-5 2 3
4 29021563 Non-canonical reader modules of BAZ1A promote recovery from DNA damage. Pubmed 6.170E-8 7.141E-6 4.796E-5 2.857E-5 2 3
5 10880450 HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins. Pubmed 1.234E-7 7.141E-6 4.796E-5 5.713E-5 2 4
6 23555303 Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression. Pubmed 1.234E-7 7.141E-6 4.796E-5 5.713E-5 2 4
7 14759371 The histone-fold protein complex CHRAC-15/17 enhances nucleosome sliding and assembly mediated by ACF. Pubmed 1.234E-7 7.141E-6 4.796E-5 5.713E-5 2 4
8 10801849 Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. Pubmed 1.234E-7 7.141E-6 4.796E-5 5.713E-5 2 4
9 10662543 A novel family of bromodomain genes. Pubmed 2.056E-7 1.058E-5 7.104E-5 9.520E-5 2 5
10 21172662 The ACF1 complex is required for DNA double-strand break repair in human cells. Pubmed 3.084E-7 1.190E-5 7.992E-5 1.428E-4 2 6
11 11980720 WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci. Pubmed 3.084E-7 1.190E-5 7.992E-5 1.428E-4 2 6
12 16514417 The chromatin remodelling complex WSTF-SNF2h interacts with nuclear myosin 1 and has a role in RNA polymerase I transcription. Pubmed 3.084E-7 1.190E-5 7.992E-5 1.428E-4 2 6
13 16603771 The WSTF-SNF2h chromatin remodeling complex interacts with several nuclear proteins in transcription. Pubmed 5.756E-7 1.904E-5 1.279E-4 2.665E-4 2 8
14 27235625 Human DNA polymerase ε is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. Pubmed 5.756E-7 1.904E-5 1.279E-4 2.665E-4 2 8
15 12374985 SATB1 targets chromatin remodelling to regulate genes over long distances. Pubmed 7.400E-7 2.284E-5 1.534E-4 3.426E-4 2 9
16 21705323 Studies on human DNA polymerase epsilon and GINS complex and their role in DNA replication. Pubmed 9.250E-7 2.677E-5 1.798E-4 4.283E-4 2 10
17 23319141 The proteomic investigation of chromatin functional domains reveals novel synergisms among distinct heterochromatin components. Pubmed 1.130E-6 3.079E-5 2.068E-4 5.234E-4 2 11
18 24025402 An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse. Pubmed 3.143E-6 8.085E-5 5.430E-4 1.455E-3 2 18
19 18162579 Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1. Pubmed 3.903E-6 9.510E-5 6.387E-4 1.807E-3 2 20
20 23086144 BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs. Pubmed 9.544E-6 2.209E-4 1.484E-3 4.419E-3 2 31
21 22242598 Human CCAAT/enhancer-binding protein β interacts with chromatin remodeling complexes of the imitation switch subfamily. Pubmed 2.312E-5 4.229E-4 2.840E-3 1.071E-2 2 48
22 22711520 Genome-scale study of transcription factor expression in the branching mouse lung. Pubmed 3.505E-5 4.229E-4 2.840E-3 1.623E-2 2 59
23 22412018 A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells. Pubmed 1.481E-4 4.229E-4 2.840E-3
6.856E-2
2 121
24 27462121 The combination of sequence-specific and nonspecific DNA-binding modes of transcription factor SATB1. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
25 25586771 Special AT-rich sequence-binding protein-1 participates in the maintenance of breast cancer stem cells through regulation of the Notch signaling pathway and expression of Snail1 and Twist1. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
26 17376900 SATB1-binding sequences and Alu-like motifs define a unique chromatin context in the vicinity of human immunodeficiency virus type 1 integration sites. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
27 24990377 Human ISWI complexes are targeted by SMARCA5 ATPase and SLIDE domains to help resolve lesion-stalled transcription. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
28 25896016 Suppressive effect of SATB1 on hepatic stellate cell activation and liver fibrosis in rats. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
29 19072498 Is SATB1 a master regulator in breast cancer growth and metastasis? Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
30 1505028 A tissue-specific MAR/SAR DNA-binding protein with unusual binding site recognition. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
31 27697109 Epigenetic regulation of long noncoding RNA UCA1 by SATB1 in breast cancer. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
32 27329137 Rare disruptive mutations and their contribution to the heritable risk of colorectal cancer. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
33 28801365 Overexpression of SATB1 Gene Inhibits the Immunosuppressive Function of Regulatory T Cells in Chronic Hepatitis B. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
34 27783844 SATB1 promotes tumor metastasis and invasiveness in oral squamous cell carcinoma. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
35 24413636 Efficient genome engineering by targeted homologous recombination in mouse embryos using transcription activator-like effector nucleases. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
36 18722016 SATB1 is required for CD8 coreceptor reversal. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
37 18378394 The human homolog of fission yeast Rad17 is implicated in tumor growth. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
38 10208430 hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
39 15970696 A nuclear targeting determinant for SATB1, a genome organizer in the T cell lineage. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
40 23691993 SLIDE, the protein interacting domain of Imitation Switch remodelers, binds DDT-domain proteins of different subfamilies in chromatin remodeling complexes. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
41 20584685 [Expression of special AT-rich sequence-binding protein in bladder urothelial carcinoma and its clinical significance]. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
42 22879953 Regulation of DNA replication timing on human chromosome by a cell-type specific DNA binding protein SATB1. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
43 16377216 The behavior of SATB1, a MAR-binding protein, in response to apoptosis stimulation. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
44 10716941 The MAR-binding protein SATB1 orchestrates temporal and spatial expression of multiple genes during T-cell development. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
45 9869296 The mammalian Rad24 homologous to yeast Saccharomyces cerevisiae Rad24 and Schizosaccharomyces pombe Rad17 is involved in DNA damage checkpoint. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
46 26755828 Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
47 26165840 Wnt/β-catenin signaling regulated SATB1 promotes colorectal cancer tumorigenesis and progression. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
48 24938377 Role of tissue-specific AT-rich DNA sequence-binding proteins in lymphocyte differentiation. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
49 9828126 A novel human gene, WSTF, is deleted in Williams syndrome. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
50 20595686 The role of SATB1 in breast cancer pathogenesis. Pubmed 1.571E-4 4.229E-4 2.840E-3
7.274E-2
1 1
Show 45 more annotations

9: Interaction [Display Chart] 6 input genes in category / 259 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:POLE3 POLE3 interactions 1.151E-10 2.981E-8 1.829E-7 2.981E-8 4 31
2 int:BAZ1A BAZ1A interactions 4.509E-10 5.839E-8 3.583E-7 1.168E-7 4 43
3 int:POLE4 POLE4 interactions 2.092E-8 1.806E-6 1.108E-5 5.418E-6 3 19
4 int:SMARCA5 SMARCA5 interactions 7.530E-8 4.875E-6 2.992E-5 1.950E-5 4 151
5 int:RAD17 RAD17 interactions 1.410E-7 7.304E-6 4.482E-5 3.652E-5 3 35
6 int:POLE2 POLE2 interactions 2.850E-7 1.230E-5 7.549E-5 7.382E-5 3 44
7 int:SMARCA1 SMARCA1 interactions 3.488E-7 1.291E-5 7.919E-5 9.034E-5 3 47
8 int:POLE POLE interactions 7.728E-7 2.502E-5 1.535E-4 2.002E-4 3 61
9 int:CHRAC1 CHRAC1 interactions 4.432E-5 1.275E-3 7.826E-3 1.148E-2 2 31
10 int:FOXC2 FOXC2 interactions 5.668E-5 1.468E-3 9.007E-3 1.468E-2 2 35
11 int:FOXC1 FOXC1 interactions 1.118E-4 2.413E-3 1.480E-2 2.895E-2 2 49
12 int:BAZ1B BAZ1B interactions 1.118E-4 2.413E-3 1.480E-2 2.895E-2 2 49
13 int:SATB1 SATB1 interactions 1.260E-4 2.510E-3 1.540E-2 3.263E-2 2 52
14 int:CDT1 CDT1 interactions 2.034E-4 3.762E-3 2.309E-2
5.267E-2
2 66
15 int:FOXS1 FOXS1 interactions 2.842E-4 4.670E-3 2.865E-2
7.361E-2
2 78
16 int:FOXE1 FOXE1 interactions 2.915E-4 4.670E-3 2.865E-2
7.551E-2
2 79
17 int:TOP2B TOP2B interactions 3.065E-4 4.670E-3 2.865E-2
7.938E-2
2 81
18 int:HUS1 HUS1 interactions 3.296E-4 4.743E-3 2.910E-2
8.537E-2
2 84
19 int:FOXG1 FOXG1 interactions 3.868E-4 5.119E-3 3.141E-2
1.002E-1
2 91
20 int:MBD3 MBD3 interactions 3.953E-4 5.119E-3 3.141E-2
1.024E-1
2 92
21 int:FOXQ1 FOXQ1 interactions 5.444E-4 6.714E-3 4.120E-2
1.410E-1
2 108
22 int:TEAD2 TEAD2 interactions 6.276E-4 7.312E-3 4.487E-2
1.626E-1
2 116
23 int:SCARNA22 SCARNA22 interactions 6.494E-4 7.312E-3 4.487E-2
1.682E-1
2 118
24 int:RHD RHD interactions 6.778E-4 7.314E-3 4.488E-2
1.755E-1
1 2
25 int:SAP18 SAP18 interactions 7.283E-4 7.487E-3 4.594E-2
1.886E-1
2 125
26 int:FOXL1 FOXL1 interactions 7.516E-4 7.487E-3 4.594E-2
1.947E-1
2 127
27 int:FOXB1 FOXB1 interactions 8.487E-4 8.141E-3 4.995E-2
2.198E-1
2 135
28 int:RBPJ RBPJ interactions 8.866E-4 8.201E-3
5.032E-2
2.296E-1
2 138
29 int:SMARCC1 SMARCC1 interactions 1.060E-3 8.973E-3
5.506E-2
2.746E-1
2 151
30 int:NFATC1 NFATC1 interactions 1.060E-3 8.973E-3
5.506E-2
2.746E-1
2 151
31 int:MYBBP1A MYBBP1A interactions 1.074E-3 8.973E-3
5.506E-2
2.782E-1
2 152
32 int:SMARCC2 SMARCC2 interactions 1.279E-3 1.035E-2
6.352E-2
3.313E-1
2 166
33 int:DAXX DAXX interactions 1.356E-3 1.065E-2
6.532E-2
3.513E-1
2 171
34 int:NFATC2 NFATC2 interactions 1.671E-3 1.253E-2
7.690E-2
4.327E-1
2 190
35 int:TBX15 TBX15 interactions 1.694E-3 1.253E-2
7.690E-2
4.387E-1
1 5
36 int:MYO1C MYO1C interactions 1.998E-3 1.422E-2
8.728E-2
5.174E-1
2 208
37 int:RAD9B RAD9B interactions 2.032E-3 1.422E-2
8.728E-2
5.263E-1
1 6
38 int:HDGF HDGF interactions 2.272E-3 1.535E-2
9.418E-2
5.883E-1
2 222
39 int:CYP4F12 CYP4F12 interactions 2.370E-3 1.535E-2
9.418E-2
6.140E-1
1 7
40 int:CECR2 CECR2 interactions 2.370E-3 1.535E-2
9.418E-2
6.140E-1
1 7
41 int:SIN3A SIN3A interactions 2.478E-3 1.565E-2
9.604E-2
6.417E-1
2 232
42 int:XRCC5 XRCC5 interactions 3.535E-3 2.180E-2
1.338E-1
9.156E-1
2 278
43 int:PRKDC PRKDC interactions 3.919E-3 2.360E-2
1.448E-1
1.000E0
2 293
44 int:POLD4 POLD4 interactions 4.061E-3 2.390E-2
1.467E-1
1.000E0
1 12
45 int:HIST1H3A HIST1H3A interactions 4.600E-3 2.648E-2
1.625E-1
1.000E0
2 318
46 int:IFI16 IFI16 interactions 5.892E-3 3.174E-2
1.947E-1
1.000E0
2 361
47 int:FOXD3 FOXD3 interactions 6.423E-3 3.174E-2
1.947E-1
1.000E0
1 19
48 int:BAZ2A BAZ2A interactions 6.423E-3 3.174E-2
1.947E-1
1.000E0
1 19
49 int:HDAC2 HDAC2 interactions 6.444E-3 3.174E-2
1.947E-1
1.000E0
2 378
50 int:RPL10 RPL10 interactions 6.746E-3 3.174E-2
1.947E-1
1.000E0
2 387
Show 45 more annotations

10: Cytoband [Display Chart] 6 input genes in category / 6 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 14q21-q22 14q21-q22 3.462E-4 1.039E-3 2.544E-3 2.077E-3 1 2
2 4q31.1-q31.2 4q31.1-q31.2 3.462E-4 1.039E-3 2.544E-3 2.077E-3 1 2
3 3p23 3p23 6.923E-4 1.385E-3 3.392E-3 4.154E-3 1 4
4 9q33 9q33 1.384E-3 2.076E-3 5.087E-3 8.305E-3 1 8
5 5q13 5q13 3.803E-3 4.563E-3 1.118E-2 2.282E-2 1 22
6 7q11.23 7q11.23 1.770E-2 1.770E-2 4.336E-2
1.062E-1
1 103
Show 1 more annotation

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 77 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 535 DNA polymerases genenames.org 1.525E-5 7.626E-5 1.741E-4 7.626E-5 2 23
2 527 CUT class homeoboxes and pseudogenes genenames.org 2.471E-3 5.946E-3 1.358E-2 1.236E-2 1 9
3 1058 ATAC complex genenames.org 3.568E-3 5.946E-3 1.358E-2 1.784E-2 1 13
4 532 GATA zinc finger domain containing|Myb/SANT domain containing genenames.org 1.448E-2 1.810E-2 4.133E-2
7.241E-2
1 53
5 88 Zinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases genenames.org 2.449E-2 2.449E-2
5.592E-2
1.225E-1
1 90

13: Coexpression [Display Chart] 6 input genes in category / 857 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M9372 Genes involved in DNA replication, compiled manually by the authors. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.855E-6 4.161E-3 3.050E-2 4.161E-3 3 146
2 M3191 Genes down-regulated in comparison of IgD+ peripheral blood B cells versus dark zone germincal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.248E-5 5.350E-3 3.922E-2 1.070E-2 3 200
3 M11563 Genes involved in DNA repair, compiled manually by the authors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.897E-5 5.419E-3 3.973E-2 1.626E-2 3 230
4 M8702 Genes down-regulated in NHEK cells (normal keratinocytes) by UV-B irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.942E-5 1.059E-2
7.762E-2
4.235E-2 3 317
5 15572690-SuppTable4 Mouse Leukemia Walter04 85genes GeneSigDB 1.267E-4 2.031E-2
1.489E-1
1.086E-1
2 68
6 17804718-Table1 Mouse Breast Deeb07 119genes GeneSigDB 3.258E-4 2.031E-2
1.489E-1
2.792E-1
2 109
7 M16922 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing t(9;11) translocation. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.630E-4 2.031E-2
1.489E-1
3.968E-1
2 130
8 M2800 Genes up-regulated in primary keratinocytes from RB1 [Gene ID=5925] skin specific knockout mice. MSigDB C6: Oncogenic Signatures (v6.0) 5.140E-4 2.031E-2
1.489E-1
4.405E-1
2 137
9 M6707 Genes up-regulated in endothelial cells: untreated versus exposed to E. burgdoferi. MSigDB C7: Immunologic Signatures (v6.0) 6.404E-4 2.031E-2
1.489E-1
5.488E-1
2 153
10 19286929-SuppTable2a Mouse Lung Rangasamy09 168genes GeneSigDB 6.488E-4 2.031E-2
1.489E-1
5.560E-1
2 154
11 M13108 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.263E-4 2.031E-2
1.489E-1
6.225E-1
2 163
12 M6321 Genes down-regulated in spleen from DUSP1 [GeneID=1843] knockout: control versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 7.713E-4 2.031E-2
1.489E-1
6.610E-1
2 168
13 M8832 Genes up-regulated in granulocyte-monocyte progenitor versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 9.041E-4 2.031E-2
1.489E-1
7.748E-1
2 182
14 M10986 Marker genes down-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.016E-3 2.031E-2
1.489E-1
8.705E-1
2 193
15 M5495 Genes down-regulated in comparison of macrophages versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.069E-3 2.031E-2
1.489E-1
9.158E-1
2 198
16 16151515-TableS1 Mouse StemCell Forsberg05 413genes GeneSigDB 1.069E-3 2.031E-2
1.489E-1
9.158E-1
2 198
17 M6801 Genes up-regulated in T conv versus T reg FOXP3 [GeneID=50943] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.079E-3 2.031E-2
1.489E-1
9.249E-1
2 199
18 M7332 Genes down-regulated in HMC-1 (mast leukemia) cells: Cl-IB-MECA [PubChem=3035850] versus incubated with the ALL1 peptide followed by treatment with Cl-IB-MECA [PubChem=3035850]. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
19 M6211 Genes down-regulated in polymorphonuclear leukocytes (1.5h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
20 M3441 Genes up-regulated in comparison of intrathymic T progenitor cells (ITTP) versus naive CD4 [GeneID=920] T cells from cord blood. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
21 M5729 Genes down-regulated in comparison of lymph node regulatory T cells versus lymph node conventional T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
22 M3425 Genes up-regulated in comparison of control CD4 [GeneID=920] CD8 thymocytes versus those after stimulation with anti-Valpha2 antibodies. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
23 M4567 Genes down-regulated in adult DN2 thymocytes versus adult DN3 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
24 M4119 Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
25 M4868 Genes up-regulated in comparison of NKT cells versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
26 M4830 Genes up-regulated in comparison of CD4 [GeneID=920] T cells versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
27 M8600 Genes down-regulated in dendritic cells versus those sorted as ITGAX int [GeneID=3687] and EMR1 int [GeneID=2015]. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
28 M5821 Genes up-regulated in comparison of naive CD8 T cells versus exhausted CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
29 M7289 Genes down-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
30 M9696 Genes up-regulated in CD4 [GeneID=920] T helper cells Th17 treated with TGFB1 and IL6 [GeneID=7040;3569]: 10h versus 30h. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
31 M7418 Genes down-regulated in neuron cell line treated with interferon alpha for 12h: immature versus mature. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
32 M3038 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
33 M7819 Genes down-regulated in amplified multipotent progenitors versus common dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
34 M5673 Genes up-regulated in comparison of TconvLN versus TregLN (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
35 M8854 Genes down-regulated in lymphoid primed multipotent progenitors versus common lymphoid progenitors. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
36 M3199 Genes down-regulated in comparison of naive B cell versus pre-germinal tonsil B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
37 M3316 Genes up-regulated in comparison of CD4 [GeneID=920] CD8 Int thymocytes versus CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
38 M6544 Genes up-regulated in epithelial cells (24h): IFNG [GeneID=3458] versus interferon alpha. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
39 M2936 Genes down-regulated in CD8 T cells: naïve versus undergoing deletional tolerance. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
40 M7837 Genes up-regulated in NK cells: fresh versus stimulated with IL2 [GeneID=3558], IL-12 and IL15 [GeneID=3600]. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
41 M3719 Genes up-regulated in comparison of control dendritic cells (DC) at 12 h versus those stimulated with poly(I:C) (TLR3 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
42 M4044 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 2 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
43 M7045 Genes down-regulated in megakaryo-erythrocyte progenitors versus pro-B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
44 M3982 Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
45 M6068 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus untreated (6h). MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
46 M5833 Genes up-regulated in comparison of effector CD8 T cells versus exhausted CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.031E-2
1.489E-1
9.342E-1
2 200
47 15695585-Table3 Mouse StemCell Zhao05 10genes GeneSigDB 2.332E-3 4.252E-2
3.117E-1
1.000E0
1 9
48 14678979-figure3a Human Lymphoma Martinez03 15genes MCL cases (A) GeneSigDB 2.591E-3 4.626E-2
3.391E-1
1.000E0
1 10
Show 43 more annotations

14: Coexpression Atlas [Display Chart] 6 input genes in category / 444 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 6 input genes in category / 80 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 6 input genes in category / 250 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-153-3p:Functional MTI Functional MTI miRTarbase 2.046E-5 5.115E-3 3.120E-2 5.115E-3 2 85
2 hsa-miR-100-5p:Functional MTI Functional MTI miRTarbase 1.787E-4 2.234E-2
1.363E-1
4.468E-2 2 251
3 TACGGGT,MIR-99B:MSigDB TACGGGT,MIR-99B:MSigDB MSigDB 1.909E-3 2.956E-2
1.803E-1
4.772E-1
1 23
4 TACGGGT,MIR-99A:MSigDB TACGGGT,MIR-99A:MSigDB MSigDB 1.909E-3 2.956E-2
1.803E-1
4.772E-1
1 23
5 TACGGGT,MIR-100:MSigDB TACGGGT,MIR-100:MSigDB MSigDB 1.909E-3 2.956E-2
1.803E-1
4.772E-1
1 23
6 hsa-miR-100:PITA hsa-miR-100:PITA TOP PITA 2.738E-3 2.956E-2
1.803E-1
6.844E-1
1 33
7 hsa-miR-99a:PITA hsa-miR-99a:PITA TOP PITA 2.738E-3 2.956E-2
1.803E-1
6.844E-1
1 33
8 hsa-miR-99b:PITA hsa-miR-99b:PITA TOP PITA 2.738E-3 2.956E-2
1.803E-1
6.844E-1
1 33
9 hsa-miR-99b-5p:TargetScan hsa-miR-99b-5p TargetScan 3.566E-3 2.956E-2
1.803E-1
8.915E-1
1 43
10 hsa-miR-100-5p:TargetScan hsa-miR-100-5p TargetScan 3.566E-3 2.956E-2
1.803E-1
8.915E-1
1 43
11 hsa-miR-99a-5p:TargetScan hsa-miR-99a-5p TargetScan 3.566E-3 2.956E-2
1.803E-1
8.915E-1
1 43
12 hsa-miR-2909:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.566E-3 2.956E-2
1.803E-1
8.915E-1
1 43
13 hsa-miR-191-5p:TargetScan hsa-miR-191-5p TargetScan 3.649E-3 2.956E-2
1.803E-1
9.123E-1
1 44
14 hsa-miR-3162-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.311E-3 2.956E-2
1.803E-1
1.000E0
1 52
15 hsa-miR-99b-5p:Functional MTI Functional MTI miRTarbase 4.394E-3 2.956E-2
1.803E-1
1.000E0
1 53
16 hsa-miR-3667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.394E-3 2.956E-2
1.803E-1
1.000E0
1 53
17 hsa-miR-3145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.642E-3 2.956E-2
1.803E-1
1.000E0
1 56
18 GGTGAAG,MIR-412:MSigDB GGTGAAG,MIR-412:MSigDB MSigDB 4.642E-3 2.956E-2
1.803E-1
1.000E0
1 56
19 hsa-miR-581:Functional MTI Functional MTI miRTarbase 4.725E-3 2.956E-2
1.803E-1
1.000E0
1 57
20 hsa-miR-8069:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.808E-3 2.956E-2
1.803E-1
1.000E0
1 58
21 hsa-miR-4417:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.890E-3 2.956E-2
1.803E-1
1.000E0
1 59
22 hsa-miR-145-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.973E-3 2.956E-2
1.803E-1
1.000E0
1 60
23 TACAATC,MIR-508:MSigDB TACAATC,MIR-508:MSigDB MSigDB 5.056E-3 2.956E-2
1.803E-1
1.000E0
1 61
24 hsa-miR-299-5p:Functional MTI Functional MTI miRTarbase 5.221E-3 2.956E-2
1.803E-1
1.000E0
1 63
25 hsa-miR-4760-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.956E-2
1.803E-1
1.000E0
1 63
26 hsa-miR-606:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.956E-2
1.803E-1
1.000E0
1 63
27 hsa-miR-8061:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.956E-2
1.803E-1
1.000E0
1 63
28 hsa-miR-219a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.956E-2
1.803E-1
1.000E0
1 63
29 AGGAGTG,MIR-483:MSigDB AGGAGTG,MIR-483:MSigDB MSigDB 5.221E-3 2.956E-2
1.803E-1
1.000E0
1 63
30 ATCTTGC,MIR-31:MSigDB ATCTTGC,MIR-31:MSigDB MSigDB 5.387E-3 2.956E-2
1.803E-1
1.000E0
1 65
31 hsa-miR-4296:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.387E-3 2.956E-2
1.803E-1
1.000E0
1 65
32 hsa-miR-4322:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.469E-3 2.956E-2
1.803E-1
1.000E0
1 66
33 hsa-miR-4265:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.469E-3 2.956E-2
1.803E-1
1.000E0
1 66
34 hsa-miR-4679:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.717E-3 2.956E-2
1.803E-1
1.000E0
1 69
35 hsa-miR-376a-5p:Functional MTI Functional MTI miRTarbase 5.800E-3 2.956E-2
1.803E-1
1.000E0
1 70
36 hsa-miR-8070:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.048E-3 2.956E-2
1.803E-1
1.000E0
1 73
37 hsa-miR-2054:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.213E-3 2.956E-2
1.803E-1
1.000E0
1 75
38 CTCCAAG,MIR-432:MSigDB CTCCAAG,MIR-432:MSigDB MSigDB 6.296E-3 2.956E-2
1.803E-1
1.000E0
1 76
39 hsa-miR-548b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.378E-3 2.956E-2
1.803E-1
1.000E0
1 77
40 hsa-miR-191:PITA hsa-miR-191:PITA TOP PITA 6.378E-3 2.956E-2
1.803E-1
1.000E0
1 77
41 hsa-miR-191-5p:Functional MTI Functional MTI miRTarbase 6.461E-3 2.956E-2
1.803E-1
1.000E0
1 78
42 hsa-miR-541:PITA hsa-miR-541:PITA TOP PITA 6.461E-3 2.956E-2
1.803E-1
1.000E0
1 78
43 hsa-miR-151a-5p:Functional MTI Functional MTI miRTarbase 6.544E-3 2.956E-2
1.803E-1
1.000E0
1 79
44 hsa-miR-8076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.626E-3 2.956E-2
1.803E-1
1.000E0
1 80
45 hsa-miR-654-5p:PITA hsa-miR-654-5p:PITA TOP PITA 6.626E-3 2.956E-2
1.803E-1
1.000E0
1 80
46 hsa-miR-4511:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.957E-3 2.956E-2
1.803E-1
1.000E0
1 84
47 AGGCACT,MIR-515-3P:MSigDB AGGCACT,MIR-515-3P:MSigDB MSigDB 7.039E-3 2.956E-2
1.803E-1
1.000E0
1 85
48 hsa-miR-644a:Functional MTI Functional MTI miRTarbase 7.700E-3 2.956E-2
1.803E-1
1.000E0
1 93
49 hsa-miR-3143:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.700E-3 2.956E-2
1.803E-1
1.000E0
1 93
50 hsa-miR-299-3p:TargetScan hsa-miR-299-3p TargetScan 7.782E-3 2.956E-2
1.803E-1
1.000E0
1 94
Show 45 more annotations

17: Drug [Display Chart] 6 input genes in category / 1387 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID003081982 AC1MIXXG Stitch 4.155E-11 5.763E-8 4.502E-7 5.763E-8 4 31
2 CID000449220 AC1L9MVH Stitch 6.839E-9 4.743E-6 3.705E-5 9.486E-6 3 17
3 CID000002100 alpha-Amanitin Stitch 2.524E-6 1.081E-3 8.447E-3 3.501E-3 3 116
4 CID006914639 AC1OCADI Stitch 3.558E-6 1.081E-3 8.447E-3 4.935E-3 3 130
5 CID000429118 poly(vA Stitch 9.814E-6 1.081E-3 8.447E-3 1.361E-2 2 19
6 CID000126441 5-ClAU Stitch 9.814E-6 1.081E-3 8.447E-3 1.361E-2 2 19
7 CID000130774 dercitin Stitch 9.814E-6 1.081E-3 8.447E-3 1.361E-2 2 19
8 CID000163040 aucubigenin Stitch 9.814E-6 1.081E-3 8.447E-3 1.361E-2 2 19
9 CID000454146 OXT-ATP Stitch 1.090E-5 1.081E-3 8.447E-3 1.512E-2 2 20
10 CID003010960 AC1MHT6K Stitch 1.090E-5 1.081E-3 8.447E-3 1.512E-2 2 20
11 CID000002028 ATP,Gamma S Stitch 1.095E-5 1.081E-3 8.447E-3 1.519E-2 3 189
12 CID000323259 parazoanthoxanthin A Stitch 1.205E-5 1.081E-3 8.447E-3 1.671E-2 2 21
13 CID000122664 AC1L3V16 Stitch 1.205E-5 1.081E-3 8.447E-3 1.671E-2 2 21
14 CID000072244 U-78036 Stitch 1.325E-5 1.081E-3 8.447E-3 1.838E-2 2 22
15 CID006438404 BVdUTP Stitch 1.325E-5 1.081E-3 8.447E-3 1.838E-2 2 22
16 CID006438779 petasiphenol Stitch 1.325E-5 1.081E-3 8.447E-3 1.838E-2 2 22
17 CID000480107 AC1LA211 Stitch 1.325E-5 1.081E-3 8.447E-3 1.838E-2 2 22
18 CID005273539 BrVarafUTP Stitch 1.583E-5 1.156E-3 9.028E-3 2.196E-2 2 24
19 CID006857433 AC1OAGMB Stitch 1.583E-5 1.156E-3 9.028E-3 2.196E-2 2 24
20 CID000027281 AC1L1CVV Stitch 1.864E-5 1.292E-3 1.010E-2 2.585E-2 2 26
21 CID000072188 araTTP Stitch 2.013E-5 1.329E-3 1.038E-2 2.791E-2 2 27
22 CID000506602 R)-PCV-TP Stitch 2.167E-5 1.345E-3 1.051E-2 3.006E-2 2 28
23 CID000469173 AC1LAIP3 Stitch 2.327E-5 1.345E-3 1.051E-2 3.228E-2 2 29
24 CID003000477 UC-3 Stitch 2.327E-5 1.345E-3 1.051E-2 3.228E-2 2 29
25 CID000143181 butylphenyl Stitch 2.665E-5 1.460E-3 1.141E-2 3.696E-2 2 31
26 CID000002210 NSC351140 Stitch 2.778E-5 1.460E-3 1.141E-2 3.854E-2 3 258
27 CID000084000 acyclovir triphosphate Stitch 2.842E-5 1.460E-3 1.141E-2 3.942E-2 2 32
28 CID000123713 BuPdGTP Stitch 3.214E-5 1.592E-3 1.244E-2 4.458E-2 2 34
29 CID000667554 L-BVAU Stitch 4.026E-5 1.925E-3 1.504E-2
5.584E-2
2 38
30 CID000072957 AC1L2J0W Stitch 4.928E-5 2.278E-3 1.780E-2
6.835E-2
2 42
31 CID000001682 1IIg Stitch 5.665E-5 2.455E-3 1.918E-2
7.857E-2
2 45
32 CID000146390 benzophenone-4-maleimide Stitch 5.665E-5 2.455E-3 1.918E-2
7.857E-2
2 45
33 CID000073432 brusatol Stitch 5.921E-5 2.489E-3 1.944E-2
8.213E-2
2 46
34 CID000008606 captan Stitch 6.184E-5 2.523E-3 1.971E-2
8.577E-2
2 47
35 CID000072187 AZTTP Stitch 6.726E-5 2.665E-3 2.082E-2
9.328E-2
2 49
36 CID000004156 methyl methanesulfonate Stitch 7.747E-5 2.953E-3 2.307E-2
1.075E-1
3 364
37 CID000002235 NSC615828 Stitch 7.877E-5 2.953E-3 2.307E-2
1.093E-1
2 53
38 CID000148252 S-(6-purinyl)-N-acetyl-L-cysteine Stitch 9.119E-5 3.328E-3 2.600E-2
1.265E-1
2 57
39 CID000444685 AC1L9GQ0 Stitch 9.444E-5 3.359E-3 2.624E-2
1.310E-1
2 58
40 CID000004844 Therarubicin Stitch 1.011E-4 3.506E-3 2.739E-2
1.402E-1
2 60
41 CID000005280 3'-deoxythymidine Stitch 1.045E-4 3.536E-3 2.762E-2
1.450E-1
2 61
42 CID000015277 p-azoxyanisole Stitch 1.262E-4 4.167E-3 3.255E-2
1.750E-1
2 67
43 CID000554048 methyl-dl-serine hydrochloride Stitch 1.339E-4 4.229E-3 3.304E-2
1.857E-1
2 69
44 CID000003657 hydroxyurea Stitch 1.342E-4 4.229E-3 3.304E-2
1.861E-1
3 438
45 CID000000625 AC1Q6S3R Stitch 1.418E-4 4.369E-3 3.413E-2
1.966E-1
2 71
46 CID000003860 AC1L1GVK Stitch 1.625E-4 4.795E-3 3.746E-2
2.254E-1
2 76
47 CID000005718 2',3'-dideoxycytidine (ddC Stitch 1.625E-4 4.795E-3 3.746E-2
2.254E-1
2 76
48 CID000007019 9-aminoacridine Stitch 1.756E-4 5.074E-3 3.964E-2
2.435E-1
2 79
49 CID000009215 acridine Stitch 1.846E-4 5.225E-3 4.082E-2
2.560E-1
2 81
50 CID000444118 AC1L9FQV Stitch 1.892E-4 5.248E-3 4.100E-2
2.624E-1
2 82
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 174 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0279980 Extraosseous Ewings sarcoma-primitive neuroepithelial tumor DisGeNET Curated 2.158E-3 3.681E-2
2.113E-1
3.755E-1
1 7
2 C4022386 Overfriendliness DisGeNET Curated 2.466E-3 3.681E-2
2.113E-1
4.291E-1
1 8
3 C4025788 Nystagmus-induced head nodding DisGeNET Curated 2.774E-3 3.681E-2
2.113E-1
4.827E-1
1 9
4 C2826321 Refractory Thrombocytopenia DisGeNET BeFree 2.774E-3 3.681E-2
2.113E-1
4.827E-1
1 9
5 C0024793 Marek Disease DisGeNET BeFree 3.082E-3 3.681E-2
2.113E-1
5.363E-1
1 10
6 C3495498 Cardiomyopathy, Familial Hypertrophic, 1 (disorder) DisGeNET Curated 3.082E-3 3.681E-2
2.113E-1
5.363E-1
1 10
7 C0332606 Elfin facies DisGeNET Curated 3.082E-3 3.681E-2
2.113E-1
5.363E-1
1 10
8 C0221209 Pelvic kidney DisGeNET Curated 3.082E-3 3.681E-2
2.113E-1
5.363E-1
1 10
9 C0034880 Hyperacusis DisGeNET Curated 3.390E-3 3.681E-2
2.113E-1
5.898E-1
1 11
10 C0751466 Phonophobia DisGeNET Curated 3.390E-3 3.681E-2
2.113E-1
5.898E-1
1 11
11 C0424810 Periorbital swelling DisGeNET Curated 4.005E-3 3.681E-2
2.113E-1
6.969E-1
1 13
12 C0151205 Periorbital edema DisGeNET Curated 4.005E-3 3.681E-2
2.113E-1
6.969E-1
1 13
13 C0149754 Cellulitis of periorbital region DisGeNET Curated 4.005E-3 3.681E-2
2.113E-1
6.969E-1
1 13
14 C0003499 Supravalvular aortic stenosis DisGeNET Curated 4.005E-3 3.681E-2
2.113E-1
6.969E-1
1 13
15 C0345030 Peripheral pulmonary artery stenosis DisGeNET Curated 4.313E-3 3.681E-2
2.113E-1
7.504E-1
1 14
16 C0012819 Diverticular disease of colon DisGeNET Curated 4.620E-3 3.681E-2
2.113E-1
8.039E-1
1 15
17 C0012811 Colon diverticulum anatomic structure DisGeNET Curated 4.620E-3 3.681E-2
2.113E-1
8.039E-1
1 15
18 C0234144 Dysgraphia DisGeNET Curated 4.928E-3 3.681E-2
2.113E-1
8.574E-1
1 16
19 C1836150 Gait imbalance DisGeNET Curated 5.235E-3 3.681E-2
2.113E-1
9.109E-1
1 17
20 C0426848 Sacral dimples DisGeNET Curated 5.542E-3 3.681E-2
2.113E-1
9.643E-1
1 18
21 C0266623 Congenital anomaly of neck DisGeNET Curated 5.849E-3 3.681E-2
2.113E-1
1.000E0
1 19
22 C4280628 Malformation of the neck DisGeNET Curated 5.849E-3 3.681E-2
2.113E-1
1.000E0
1 19
23 C0575167 Deformity of neck DisGeNET Curated 5.849E-3 3.681E-2
2.113E-1
1.000E0
1 19
24 C1856872 Sloping shoulders DisGeNET Curated 6.464E-3 3.681E-2
2.113E-1
1.000E0
1 21
25 C0020545 Hypertension, Renovascular DisGeNET Curated 6.464E-3 3.681E-2
2.113E-1
1.000E0
1 21
26 C1837279 Hypoplastic toenails DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
27 C4280369 Flattening of the zygomatic bone DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
28 C4280370 Depressed cheekbone DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
29 C4072879 Small cheekbone DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
30 C4021242 Hypoplasia of the zygomatic bone DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
31 C4280368 Hypotrophic cheekbone DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
32 C0266061 Open Bite DisGeNET Curated 6.770E-3 3.681E-2
2.113E-1
1.000E0
1 22
33 C4024665 High-grade hypermetropia DisGeNET Curated 7.997E-3 4.093E-2
2.349E-1
1.000E0
1 26
34 C0018536 Hallux Valgus DisGeNET Curated 7.997E-3 4.093E-2
2.349E-1
1.000E0
1 26
35 C0006386 Bunion DisGeNET Curated 8.304E-3 4.104E-2
2.355E-1
1.000E0
1 27
36 C0581342 Redundant skin DisGeNET Curated 8.611E-3 4.104E-2
2.355E-1
1.000E0
1 28
37 C4280615 Defective tooth enamel DisGeNET Curated 9.530E-3 4.104E-2
2.355E-1
1.000E0
1 31
38 C4280262 Dystrophic tooth enamel DisGeNET Curated 9.530E-3 4.104E-2
2.355E-1
1.000E0
1 31
39 C3551535 Mitral regurgitation, mild DisGeNET Curated 9.836E-3 4.104E-2
2.355E-1
1.000E0
1 32
40 C1853195 Prostate Cancer, Hereditary, 7 DisGeNET Curated 9.836E-3 4.104E-2
2.355E-1
1.000E0
1 32
41 C0026266 Mitral Valve Insufficiency DisGeNET Curated 1.014E-2 4.104E-2
2.355E-1
1.000E0
1 33
42 C4021800 Enamel abnormalities DisGeNET Curated 1.014E-2 4.104E-2
2.355E-1
1.000E0
1 33
43 C1844505 Pointed chin DisGeNET Curated 1.014E-2 4.104E-2
2.355E-1
1.000E0
1 33
44 C0917801 Sleeplessness DisGeNET Curated 1.045E-2 4.132E-2
2.371E-1
1.000E0
1 34
45 C1867873 Failure to thrive in infancy DisGeNET Curated 1.075E-2 4.158E-2
2.386E-1
1.000E0
1 35
46 C0015371 Extrapyramidal Disorders DisGeNET Curated 1.137E-2 4.231E-2
2.428E-1
1.000E0
1 37
47 C4020847 Abnormality of pelvic girdle bone morphology DisGeNET Curated 1.167E-2 4.231E-2
2.428E-1
1.000E0
1 38
48 C0019825 Hoarseness DisGeNET Curated 1.167E-2 4.231E-2
2.428E-1
1.000E0
1 38
49 C0405581 Testicular dysfunction DisGeNET BeFree 1.198E-2 4.253E-2
2.441E-1
1.000E0
1 39
50 C0600104 Obsessive compulsive behavior DisGeNET Curated 1.259E-2 4.316E-2
2.477E-1
1.000E0
1 41
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