Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc136_9, positive side

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1: GO: Molecular Function [Display Chart] 9 input genes in category / 48 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0017134 fibroblast growth factor binding 7.212E-5 3.462E-3 1.544E-2 3.462E-3 2 27
2 GO:0070551 endoribonuclease activity, cleaving siRNA-paired mRNA 4.823E-4 7.717E-3 3.441E-2 2.315E-2 1 1
3 GO:0090624 endoribonuclease activity, cleaving miRNA-paired mRNA 4.823E-4 7.717E-3 3.441E-2 2.315E-2 1 1
4 GO:0030395 lactose binding 1.446E-3 1.599E-2
7.129E-2
6.942E-2
 1 3
5 GO:0000340 RNA 7-methylguanosine cap binding 1.928E-3 1.599E-2
7.129E-2
9.254E-2
 1 4
6 GO:0019838 growth factor binding 1.999E-3 1.599E-2
7.129E-2
9.594E-2
 2 142
7 GO:0048030 disaccharide binding 2.409E-3 1.652E-2
7.367E-2
1.157E-1
 1 5
8 GO:0005534 galactose binding 3.372E-3 2.023E-2
9.020E-2
1.618E-1
 1 7
9 GO:0035197 siRNA binding 3.853E-3 2.055E-2
9.161E-2
1.849E-1
 1 8
10 GO:0008022 protein C-terminus binding 4.885E-3 2.310E-2
1.030E-1
2.345E-1
 2 224
11 GO:0070492 oligosaccharide binding 5.294E-3 2.310E-2
1.030E-1
2.541E-1
 1 11
12 GO:0000339 RNA cap binding 6.254E-3 2.501E-2
1.115E-1
3.002E-1
 1 13
13 GO:0035198 miRNA binding 8.171E-3 3.017E-2
1.345E-1
3.922E-1
 1 17
14 GO:0000993 RNA polymerase II complex binding 9.128E-3 3.130E-2
1.395E-1
4.382E-1
 1 19
15 GO:0043175 RNA polymerase core enzyme binding 1.104E-2 3.533E-2
1.575E-1
5.299E-1
 1 23
16 GO:0001099 basal RNA polymerase II transcription machinery binding 1.343E-2 3.791E-2
1.690E-1
6.445E-1
 1 28
17 GO:0001098 basal transcription machinery binding 1.343E-2 3.791E-2
1.690E-1
6.445E-1
 1 28
18 GO:0043236 laminin binding 1.533E-2 3.993E-2
1.781E-1
7.359E-1
 1 32
19 GO:0015036 disulfide oxidoreductase activity 1.581E-2 3.993E-2
1.781E-1
7.587E-1
 1 33
20 GO:0070063 RNA polymerase binding 1.771E-2 4.047E-2
1.805E-1
8.500E-1
 1 37
21 GO:0016891 endoribonuclease activity, producing 5'-phosphomonoesters 1.771E-2 4.047E-2
1.805E-1
8.500E-1
 1 37
22 GO:0016893 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters 2.245E-2 4.897E-2
2.184E-1
1.000E0
 1 47
Show 17 more annotations

2: GO: Biological Process [Display Chart] 8 input genes in category / 189 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0000387 spliceosomal snRNP assembly 1.573E-15 2.973E-13 1.731E-12 2.973E-13 6 39
2 GO:0022618 ribonucleoprotein complex assembly 1.553E-13 1.365E-11 7.947E-11 2.936E-11 7 208
3 GO:0071826 ribonucleoprotein complex subunit organization 2.167E-13 1.365E-11 7.947E-11 4.095E-11 7 218
4 GO:0022613 ribonucleoprotein complex biogenesis 4.741E-11 2.110E-9 1.228E-8 8.960E-9 7 468
5 GO:0006397 mRNA processing 5.581E-11 2.110E-9 1.228E-8 1.055E-8 7 479
6 GO:0000398 mRNA splicing, via spliceosome 5.006E-10 1.279E-8 7.447E-8 9.461E-8 6 305
7 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 5.006E-10 1.279E-8 7.447E-8 9.461E-8 6 305
8 GO:0000375 RNA splicing, via transesterification reactions 5.414E-10 1.279E-8 7.447E-8 1.023E-7 6 309
9 GO:0008380 RNA splicing 2.632E-9 5.527E-8 3.218E-7 4.975E-7 6 402
10 GO:0051170 import into nucleus 7.917E-8 1.496E-6 8.711E-6 1.496E-5 5 321
11 GO:0006913 nucleocytoplasmic transport 6.748E-7 1.159E-5 6.750E-5 1.275E-4 5 494
12 GO:0000245 spliceosomal complex assembly 1.506E-6 2.372E-5 1.381E-4 2.846E-4 3 57
13 GO:0033120 positive regulation of RNA splicing 8.469E-5 1.231E-3 7.168E-3 1.601E-2 2 33
14 GO:0007019 microtubule depolymerization 1.445E-4 1.951E-3 1.136E-2 2.732E-2 2 43
15 GO:0010501 RNA secondary structure unwinding 1.584E-4 1.996E-3 1.162E-2 2.994E-2 2 45
16 GO:0034117 erythrocyte aggregation 4.296E-4 4.511E-3 2.626E-2
8.119E-2
 1 1
17 GO:0034118 regulation of erythrocyte aggregation 4.296E-4 4.511E-3 2.626E-2
8.119E-2
 1 1
18 GO:0034120 positive regulation of erythrocyte aggregation 4.296E-4 4.511E-3 2.626E-2
8.119E-2
 1 1
19 GO:0031109 microtubule polymerization or depolymerization 7.067E-4 7.030E-3 4.093E-2
1.336E-1
 2 95
20 GO:0006353 DNA-templated transcription, termination 8.141E-4 7.638E-3 4.447E-2
1.539E-1
 2 102
21 GO:0051261 protein depolymerization 9.288E-4 7.638E-3 4.447E-2
1.756E-1
 2 109
22 GO:0043484 regulation of RNA splicing 9.288E-4 7.638E-3 4.447E-2
1.756E-1
 2 109
23 GO:0010975 regulation of neuron projection development 9.295E-4 7.638E-3 4.447E-2
1.757E-1
 3 492
24 GO:0090625 mRNA cleavage involved in gene silencing by siRNA 1.717E-3 1.298E-2
7.558E-2
3.246E-1
 1 4
25 GO:0035087 siRNA loading onto RISC involved in RNA interference 1.717E-3 1.298E-2
7.558E-2
3.246E-1
 1 4
26 GO:0035279 mRNA cleavage involved in gene silencing by miRNA 2.146E-3 1.449E-2
8.434E-2
4.056E-1
 1 5
27 GO:0098795 mRNA cleavage involved in gene silencing 2.146E-3 1.449E-2
8.434E-2
4.056E-1
 1 5
28 GO:0002317 plasma cell differentiation 2.146E-3 1.449E-2
8.434E-2
4.056E-1
 1 5
29 GO:2001200 positive regulation of dendritic cell differentiation 2.575E-3 1.678E-2
9.770E-2
4.867E-1
 1 6
30 GO:0035280 miRNA loading onto RISC involved in gene silencing by miRNA 3.004E-3 1.831E-2
1.066E-1
5.677E-1
 1 7
31 GO:0046598 positive regulation of viral entry into host cell 3.004E-3 1.831E-2
1.066E-1
5.677E-1
 1 7
32 GO:0070922 small RNA loading onto RISC 3.432E-3 1.995E-2
1.162E-1
6.487E-1
 1 8
33 GO:0043624 cellular protein complex disassembly 3.484E-3 1.995E-2
1.162E-1
6.585E-1
 2 213
34 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening 4.716E-3 2.346E-2
1.366E-1
8.914E-1
 1 11
35 GO:0060213 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening 4.716E-3 2.346E-2
1.366E-1
8.914E-1
 1 11
36 GO:0035278 miRNA mediated inhibition of translation 4.716E-3 2.346E-2
1.366E-1
8.914E-1
 1 11
37 GO:0040033 negative regulation of translation, ncRNA-mediated 4.716E-3 2.346E-2
1.366E-1
8.914E-1
 1 11
38 GO:0045974 regulation of translation, ncRNA-mediated 4.716E-3 2.346E-2
1.366E-1
8.914E-1
 1 11
39 GO:2001198 regulation of dendritic cell differentiation 5.144E-3 2.493E-2
1.451E-1
9.723E-1
 1 12
40 GO:0000244 spliceosomal tri-snRNP complex assembly 5.572E-3 2.633E-2
1.533E-1
1.000E0
 1 13
41 GO:0032984 protein-containing complex disassembly 5.859E-3 2.637E-2
1.535E-1
1.000E0
 2 278
42 GO:0016246 RNA interference 5.999E-3 2.637E-2
1.535E-1
1.000E0
 1 14
43 GO:0031054 pre-miRNA processing 5.999E-3 2.637E-2
1.535E-1
1.000E0
 1 14
44 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 6.427E-3 2.699E-2
1.571E-1
1.000E0
 1 15
45 GO:1900153 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay 6.427E-3 2.699E-2
1.571E-1
1.000E0
 1 15
46 GO:0002313 mature B cell differentiation involved in immune response 7.281E-3 2.928E-2
1.704E-1
1.000E0
 1 17
47 GO:0031442 positive regulation of mRNA 3'-end processing 7.281E-3 2.928E-2
1.704E-1
1.000E0
 1 17
48 GO:0010586 miRNA metabolic process 7.708E-3 3.035E-2
1.767E-1
1.000E0
 1 18
49 GO:0002335 mature B cell differentiation 9.413E-3 3.558E-2
2.071E-1
1.000E0
 1 22
50 GO:0045947 negative regulation of translational initiation 9.413E-3 3.558E-2
2.071E-1
1.000E0
 1 22
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 9 input genes in category / 29 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0097504 Gemini of coiled bodies 5.827E-19 1.690E-17 6.694E-17 1.690E-17 6 11
2 GO:0032797 SMN complex 2.164E-18 3.137E-17 1.243E-16 6.275E-17 6 13
3 GO:0034719 SMN-Sm protein complex 1.560E-17 1.508E-16 5.973E-16 4.523E-16 6 17
4 GO:0016604 nuclear body 3.047E-11 2.209E-10 8.752E-10 8.837E-10 7 364
5 GO:0015030 Cajal body 1.784E-6 1.035E-5 4.099E-5 5.173E-5 3 54
6 GO:0036464 cytoplasmic ribonucleoprotein granule 3.431E-5 1.658E-4 6.570E-4 9.950E-4 3 144
7 GO:0035770 ribonucleoprotein granule 4.032E-5 1.670E-4 6.617E-4 1.169E-3 3 152
8 GO:0030018 Z disc 1.352E-3 4.901E-3 1.942E-2 3.921E-2 2 119
9 GO:0031674 I band 1.735E-3 5.560E-3 2.203E-2
5.032E-2
 2 135
10 GO:0043204 perikaryon 1.917E-3 5.560E-3 2.203E-2
5.560E-2
 2 142
11 GO:0001674 female germ cell nucleus 2.830E-3 6.838E-3 2.709E-2
8.207E-2
 1 6
12 GO:0070578 RISC-loading complex 2.830E-3 6.838E-3 2.709E-2
8.207E-2
 1 6
13 GO:0090571 RNA polymerase II transcription repressor complex 3.301E-3 6.838E-3 2.709E-2
9.573E-2
 1 7
14 GO:0035068 micro-ribonucleoprotein complex 3.301E-3 6.838E-3 2.709E-2
9.573E-2
 1 7
15 GO:0030017 sarcomere 3.684E-3 7.122E-3 2.822E-2
1.068E-1
 2 198
16 GO:0044449 contractile fiber part 4.327E-3 7.515E-3 2.977E-2
1.255E-1
 2 215
17 GO:0030016 myofibril 4.526E-3 7.515E-3 2.977E-2
1.312E-1
 2 220
18 GO:0043292 contractile fiber 5.104E-3 7.515E-3 2.977E-2
1.480E-1
 2 234
19 GO:0016442 RISC complex 5.183E-3 7.515E-3 2.977E-2
1.503E-1
 1 11
20 GO:0031332 RNAi effector complex 5.183E-3 7.515E-3 2.977E-2
1.503E-1
 1 11
21 GO:0005845 mRNA cap binding complex 5.653E-3 7.806E-3 3.093E-2
1.639E-1
 1 12
22 GO:0034518 RNA cap binding complex 6.592E-3 8.690E-3 3.443E-2
1.912E-1
 1 14
23 GO:1902555 endoribonuclease complex 9.874E-3 1.245E-2 4.932E-2
2.863E-1
 1 21
24 GO:0090568 nuclear transcriptional repressor complex 1.221E-2 1.471E-2
5.827E-2
3.542E-1
 1 26
25 GO:0043073 germ cell nucleus 1.268E-2 1.471E-2
5.827E-2
3.677E-1
 1 27
26 GO:0005844 polysome 2.290E-2 2.555E-2
1.012E-1
6.642E-1
 1 49
27 GO:0000932 P-body 3.349E-2 3.597E-2
1.425E-1
9.713E-1
 1 72
28 GO:0017053 transcriptional repressor complex 3.670E-2 3.801E-2
1.506E-1
1.000E0
 1 79
Show 23 more annotations

4: Human Phenotype [Display Chart] 1 input genes in category / 107 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0011178 Alpha-EEG 4.249E-4 2.273E-2
1.195E-1
 4.546E-2 1 2
2 HP:0006959 Proximal spinal muscular atrophy 4.249E-4 2.273E-2
1.195E-1
 4.546E-2 1 2
3 HP:0011176 EEG with constitutional variants 8.498E-4 3.031E-2
1.593E-1
9.093E-2
 1 4
4 HP:0005905 Abnormal cervical curvature 2.124E-3 3.497E-2
1.838E-1
2.273E-1
 1 10
5 HP:0002378 Hand tremor 2.337E-3 3.497E-2
1.838E-1
2.501E-1
 1 11
6 HP:0002542 Olivopontocerebellar atrophy 2.549E-3 3.497E-2
1.838E-1
2.728E-1
 1 12
7 HP:0002341 Cervical cord compression 3.187E-3 3.497E-2
1.838E-1
3.410E-1
 1 15
8 HP:0002318 Cervical myelopathy 3.399E-3 3.497E-2
1.838E-1
3.637E-1
 1 16
9 HP:0005684 Distal arthrogryposis 3.399E-3 3.497E-2
1.838E-1
3.637E-1
 1 16
10 HP:0001390 Arthrogryposis 3.399E-3 3.497E-2
1.838E-1
3.637E-1
 1 16
11 HP:0005855 Multiple prenatal fractures 3.612E-3 3.497E-2
1.838E-1
3.864E-1
 1 17
12 HP:0011398 Central hypotonia 4.249E-3 3.497E-2
1.838E-1
4.546E-1
 1 20
13 HP:0003547 Shoulder girdle muscle weakness 4.249E-3 3.497E-2
1.838E-1
4.546E-1
 1 20
14 HP:0002522 Areflexia of lower limbs 5.099E-3 3.616E-2
1.900E-1
5.456E-1
 1 24
15 HP:0007126 Proximal amyotrophy 5.524E-3 3.616E-2
1.900E-1
5.910E-1
 1 26
16 HP:0003445 EMG: neuropathic changes 5.736E-3 3.616E-2
1.900E-1
6.138E-1
 1 27
17 HP:0006597 Diaphragmatic paralysis 6.586E-3 3.616E-2
1.900E-1
7.047E-1
 1 31
18 HP:0009067 Progressive spinal muscular atrophy 7.223E-3 3.616E-2
1.900E-1
7.729E-1
 1 34
19 HP:0030188 Tremor by anatomical site 7.223E-3 3.616E-2
1.900E-1
7.729E-1
 1 34
20 HP:0003741 Congenital muscular dystrophy 7.223E-3 3.616E-2
1.900E-1
7.729E-1
 1 34
21 HP:0002194 Delayed gross motor development 7.436E-3 3.616E-2
1.900E-1
7.956E-1
 1 35
22 HP:0007289 Limb fasciculations 7.436E-3 3.616E-2
1.900E-1
7.956E-1
 1 35
23 HP:0009113 Diaphragmatic weakness 8.286E-3 3.760E-2
1.976E-1
8.866E-1
 1 39
24 HP:0002398 Degeneration of anterior horn cells 9.135E-3 3.760E-2
1.976E-1
9.775E-1
 1 43
25 HP:0002203 Respiratory paralysis 9.135E-3 3.760E-2
1.976E-1
9.775E-1
 1 43
26 HP:0006802 Abnormal anterior horn cell morphology 9.135E-3 3.760E-2
1.976E-1
9.775E-1
 1 43
27 HP:0001308 Tongue fasciculations 9.985E-3 3.763E-2
1.977E-1
1.000E0
 1 47
28 HP:0002366 Abnormal lower motor neuron morphology 1.020E-2 3.763E-2
1.977E-1
1.000E0
 1 48
29 HP:0003391 Gowers sign 1.020E-2 3.763E-2
1.977E-1
1.000E0
 1 48
30 HP:0010546 Muscle fibrillation 1.083E-2 3.864E-2
2.031E-1
1.000E0
 1 51
31 HP:0008994 Proximal muscle weakness in lower limbs 1.147E-2 3.960E-2
2.081E-1
1.000E0
 1 54
32 HP:0030810 Abnormal tongue physiology 1.402E-2 4.546E-2
2.389E-1
1.000E0
 1 66
33 HP:0003325 Limb-girdle muscle weakness 1.402E-2 4.546E-2
2.389E-1
1.000E0
 1 66
34 HP:0001435 Abnormality of the shoulder girdle musculature 1.487E-2 4.680E-2
2.459E-1
1.000E0
 1 70
35 HP:0002380 Fasciculations 1.657E-2 4.925E-2
2.588E-1
1.000E0
 1 78
36 HP:0007269 Spinal muscular atrophy 1.657E-2 4.925E-2
2.588E-1
1.000E0
 1 78
Show 31 more annotations

5: Mouse Phenotype [Display Chart] 6 input genes in category / 345 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0009402 decreased skeletal muscle fiber diameter 1.852E-6 3.215E-4 2.065E-3 6.388E-4 3 48
2 MP:0013178 tail necrosis 2.796E-6 3.215E-4 2.065E-3 9.646E-4 2 5
3 MP:0003466 decreased single cell response threshold 2.796E-6 3.215E-4 2.065E-3 9.646E-4 2 5
4 MP:0003464 abnormal single cell response threshold 4.193E-6 3.335E-4 2.142E-3 1.447E-3 2 6
5 MP:0001956 hypopnea 5.868E-6 3.335E-4 2.142E-3 2.025E-3 2 7
6 MP:0001220 epidermal necrosis 7.823E-6 3.335E-4 2.142E-3 2.699E-3 2 8
7 MP:0004243 abnormal motor nerve collateral sprouting 1.006E-5 3.335E-4 2.142E-3 3.469E-3 2 9
8 MP:0003201 extremity edema 1.006E-5 3.335E-4 2.142E-3 3.469E-3 2 9
9 MP:0001730 embryonic growth arrest 1.057E-5 3.335E-4 2.142E-3 3.645E-3 4 305
10 MP:0010726 abnormal collateral sprouting 1.257E-5 3.335E-4 2.142E-3 4.335E-3 2 10
11 MP:0002883 chromatolysis 1.257E-5 3.335E-4 2.142E-3 4.335E-3 2 10
12 MP:0005356 positive geotaxis 1.257E-5 3.335E-4 2.142E-3 4.335E-3 2 10
13 MP:0004793 abnormal synaptic vesicle clustering 1.257E-5 3.335E-4 2.142E-3 4.335E-3 2 10
14 MP:0000588 thick tail 1.535E-5 3.704E-4 2.379E-3 5.297E-3 2 11
15 MP:0001053 abnormal neuromuscular synapse morphology 1.611E-5 3.704E-4 2.379E-3 5.556E-3 3 98
16 MP:0009400 decreased skeletal muscle fiber size 1.871E-5 3.796E-4 2.438E-3 6.454E-3 3 103
17 MP:0001051 abnormal somatic motor system morphology 1.871E-5 3.796E-4 2.438E-3 6.454E-3 3 103
18 MP:0001973 increased thermal nociceptive threshold 2.039E-5 3.909E-4 2.510E-3 7.036E-3 3 106
19 MP:0005576 decreased pulmonary ventilation 2.928E-5 5.247E-4 3.369E-3 1.010E-2 2 15
20 MP:0001443 poor grooming 3.346E-5 5.247E-4 3.369E-3 1.154E-2 2 16
21 MP:0003815 hairless 3.346E-5 5.247E-4 3.369E-3 1.154E-2 2 16
22 MP:0002738 hyperresponsive to tactile stimuli 3.346E-5 5.247E-4 3.369E-3 1.154E-2 2 16
23 MP:0004191 neuronal intranuclear inclusions 3.791E-5 5.449E-4 3.500E-3 1.308E-2 2 17
24 MP:0004297 abnormal proprioceptive neuron morphology 3.791E-5 5.449E-4 3.500E-3 1.308E-2 2 17
25 MP:0006404 abnormal lumbar dorsal root ganglion morphology 4.764E-5 6.087E-4 3.909E-3 1.644E-2 2 19
26 MP:0003928 increased heart rate variability 4.764E-5 6.087E-4 3.909E-3 1.644E-2 2 19
27 MP:0002914 abnormal endplate potential 4.764E-5 6.087E-4 3.909E-3 1.644E-2 2 19
28 MP:0000961 abnormal dorsal root ganglion morphology 5.216E-5 6.426E-4 4.127E-3 1.799E-2 3 145
29 MP:0008142 decreased small intestinal villus size 5.847E-5 6.905E-4 4.435E-3 2.017E-2 2 21
30 MP:0011094 embryonic lethality before implantation, complete penetrance 6.005E-5 6.905E-4 4.435E-3 2.072E-2 3 152
31 MP:0009398 abnormal skeletal muscle fiber size 6.244E-5 6.949E-4 4.463E-3 2.154E-2 3 154
32 MP:0002733 abnormal thermal nociception 6.868E-5 7.405E-4 4.756E-3 2.370E-2 3 159
33 MP:0003043 hypoalgesia 7.262E-5 7.593E-4 4.876E-3 2.506E-2 3 162
34 MP:0002338 abnormal pulmonary ventilation 9.038E-5 9.171E-4 5.890E-3 3.118E-2 2 26
35 MP:0006204 embryonic lethality before implantation 9.941E-5 9.730E-4 6.249E-3 3.430E-2 3 180
36 MP:0003082 abnormal gastrocnemius morphology 1.051E-4 9.730E-4 6.249E-3 3.625E-2 2 28
37 MP:0009412 skeletal muscle fiber degeneration 1.051E-4 9.730E-4 6.249E-3 3.625E-2 2 28
38 MP:0009406 decreased skeletal muscle fiber number 1.128E-4 9.730E-4 6.249E-3 3.892E-2 2 29
39 MP:0004144 hypotonia 1.128E-4 9.730E-4 6.249E-3 3.892E-2 2 29
40 MP:0008571 abnormal synaptic bouton morphology 1.128E-4 9.730E-4 6.249E-3 3.892E-2 2 29
41 MP:0010506 prolonged RR interval 1.208E-4 9.926E-4 6.375E-3 4.169E-2 2 30
42 MP:0004145 abnormal muscle electrophysiology 1.208E-4 9.926E-4 6.375E-3 4.169E-2 2 30
43 MP:0001957 apnea 1.291E-4 1.032E-3 6.627E-3 4.455E-2 2 31
44 MP:0009434 paraparesis 1.377E-4 1.032E-3 6.627E-3 4.751E-2 2 32
45 MP:0001078 abnormal phrenic nerve morphology 1.377E-4 1.032E-3 6.627E-3 4.751E-2 2 32
46 MP:0002663 absent blastocoele 1.466E-4 1.032E-3 6.627E-3
5.056E-2
 2 33
47 MP:0010725 thin interventricular septum 1.466E-4 1.032E-3 6.627E-3
5.056E-2
 2 33
48 MP:0003858 enhanced coordination 1.466E-4 1.032E-3 6.627E-3
5.056E-2
 2 33
49 MP:0004835 abnormal miniature endplate potential 1.466E-4 1.032E-3 6.627E-3
5.056E-2
 2 33
50 MP:0009538 abnormal synapse morphology 1.572E-4 1.085E-3 6.966E-3
5.424E-2
 3 210
Show 45 more annotations

6: Domain [Display Chart] 8 input genes in category / 53 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR010304 Survival motor neuron InterPro 4.786E-7 1.268E-5 5.779E-5 2.536E-5 2 3
2 PF06003 SMN Pfam 4.786E-7 1.268E-5 5.779E-5 2.536E-5 2 3
3 PS50304 TUDOR PROSITE 4.019E-5 7.100E-4 3.235E-3 2.130E-3 2 23
4 SM00333 TUDOR SMART 5.570E-5 7.313E-4 3.333E-3 2.952E-3 2 27
5 IPR002999 Tudor InterPro 6.899E-5 7.313E-4 3.333E-3 3.657E-3 2 30
6 IPR012337 RNaseH-like dom InterPro 3.690E-4 1.509E-3 6.875E-3 1.956E-2 2 69
7 IPR024822 Coilin InterPro 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
8 IPR031722 Coilin N InterPro 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
9 IPR028602 AGO2 InterPro 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
10 PD296126 SMN cplx gem-assoc protein 7 ProDom 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
11 IPR020338 SMN gemin7 InterPro 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
12 IPR009422 Gemin6 InterPro 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
13 PF15862 Coilin N Pfam 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
14 PF11095 Gemin7 Pfam 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
15 PF06372 Gemin6 Pfam 4.270E-4 1.509E-3 6.875E-3 2.263E-2 1 1
16 PF16488 ArgoL2 Pfam 1.707E-3 4.308E-3 1.963E-2
9.048E-2
 1 4
17 IPR032473 Argonaute Mid dom InterPro 1.707E-3 4.308E-3 1.963E-2
9.048E-2
 1 4
18 PF16487 ArgoMid Pfam 1.707E-3 4.308E-3 1.963E-2
9.048E-2
 1 4
19 PF16486 ArgoN Pfam 1.707E-3 4.308E-3 1.963E-2
9.048E-2
 1 4
20 IPR032474 Argonaute N InterPro 1.707E-3 4.308E-3 1.963E-2
9.048E-2
 1 4
21 IPR032472 ArgoL2 InterPro 1.707E-3 4.308E-3 1.963E-2
9.048E-2
 1 4
22 SM01163 DUF1785 SMART 2.133E-3 5.140E-3 2.342E-2
1.131E-1
 1 5
23 PF08699 ArgoL1 Pfam 2.560E-3 5.653E-3 2.576E-2
1.357E-1
 1 6
24 IPR014811 ArgoL1 InterPro 2.560E-3 5.653E-3 2.576E-2
1.357E-1
 1 6
25 IPR003165 Piwi InterPro 3.412E-3 6.356E-3 2.896E-2
1.808E-1
 1 8
26 PS50822 PIWI PROSITE 3.412E-3 6.356E-3 2.896E-2
1.808E-1
 1 8
27 SM00950 Piwi SMART 3.412E-3 6.356E-3 2.896E-2
1.808E-1
 1 8
28 PF02171 Piwi Pfam 3.412E-3 6.356E-3 2.896E-2
1.808E-1
 1 8
29 PF02170 PAZ Pfam 3.837E-3 6.356E-3 2.896E-2
2.034E-1
 1 9
30 PS50821 PAZ PROSITE 3.837E-3 6.356E-3 2.896E-2
2.034E-1
 1 9
31 SM00949 PAZ SMART 3.837E-3 6.356E-3 2.896E-2
2.034E-1
 1 9
32 IPR003100 PAZ dom InterPro 3.837E-3 6.356E-3 2.896E-2
2.034E-1
 1 9
33 SM00276 GLECT SMART 6.388E-3 9.151E-3 4.170E-2
3.386E-1
 1 15
34 PF00337 Gal-bind lectin Pfam 6.388E-3 9.151E-3 4.170E-2
3.386E-1
 1 15
35 IPR001079 Galectin CRD InterPro 6.388E-3 9.151E-3 4.170E-2
3.386E-1
 1 15
36 SM00908 Gal-bind lectin SMART 6.388E-3 9.151E-3 4.170E-2
3.386E-1
 1 15
37 PS51304 GALECTIN PROSITE 6.388E-3 9.151E-3 4.170E-2
3.386E-1
 1 15
38 PS00039 DEAD ATP HELICASE PROSITE 1.316E-2 1.836E-2
8.366E-2
6.977E-1
 1 31
39 IPR000629 RNA-helicase DEAD-box CS InterPro 1.401E-2 1.904E-2
8.674E-2
7.424E-1
 1 33
40 IPR014014 RNA helicase DEAD Q motif InterPro 1.569E-2 2.029E-2
9.244E-2
8.318E-1
 1 37
41 PS51195 Q MOTIF PROSITE 1.569E-2 2.029E-2
9.244E-2
8.318E-1
 1 37
42 3.30.420.10 - Gene3D 1.990E-2 2.511E-2
1.144E-1
1.000E0
 1 47
43 PF00270 DEAD Pfam 3.076E-2 3.705E-2
1.688E-1
1.000E0
 1 73
44 IPR011545 DEAD/DEAH box helicase dom InterPro 3.076E-2 3.705E-2
1.688E-1
1.000E0
 1 73
45 2.60.120.200 - Gene3D 3.986E-2 4.691E-2
2.138E-1
1.000E0
 1 95
46 SM00490 HELICc SMART 4.480E-2 4.691E-2
2.138E-1
1.000E0
 1 107
47 PF00271 Helicase C Pfam 4.480E-2 4.691E-2
2.138E-1
1.000E0
 1 107
48 IPR001650 Helicase C InterPro 4.521E-2 4.691E-2
2.138E-1
1.000E0
 1 108
49 SM00487 DEXDc SMART 4.562E-2 4.691E-2
2.138E-1
1.000E0
 1 109
50 PS51192 HELICASE ATP BIND 1 PROSITE 4.562E-2 4.691E-2
2.138E-1
1.000E0
 1 109
Show 45 more annotations

7: Pathway [Display Chart] 8 input genes in category / 37 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269732 snRNP Assembly BioSystems: REACTOME 1.236E-13 2.287E-12 9.609E-12 4.574E-12 6 53
2 1269731 Metabolism of non-coding RNA BioSystems: REACTOME 1.236E-13 2.287E-12 9.609E-12 4.574E-12 6 53
3 177876 RNA transport BioSystems: KEGG 1.683E-10 2.076E-9 8.724E-9 6.229E-9 6 171
4 1269722 Post-transcriptional silencing by small RNAs BioSystems: REACTOME 4.490E-3 4.154E-2
1.745E-1
1.661E-1
 1 7
5 1269721 Small interfering RNA (siRNA) biogenesis BioSystems: REACTOME 5.770E-3 4.270E-2
1.794E-1
2.135E-1
 1 9

8: Pubmed [Display Chart] 9 input genes in category / 1593 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 17023415 Gemin8 is required for the architecture and function of the survival motor neuron complex. Pubmed 1.117E-18 1.157E-15 9.201E-15 1.779E-15 5 6
2 18984161 An assembly chaperone collaborates with the SMN complex to generate spliceosomal SnRNPs. Pubmed 1.453E-18 1.157E-15 9.201E-15 2.314E-15 6 22
3 20513430 Gemin5 delivers snRNA precursors to the SMN complex for snRNP biogenesis. Pubmed 2.344E-17 1.245E-14 9.896E-14 3.734E-14 5 9
4 19928837 The SMN interactome includes Myb-binding protein 1a. Pubmed 1.821E-16 7.252E-14 5.766E-13 2.901E-13 6 46
5 12065586 Identification and characterization of Gemin7, a novel component of the survival of motor neuron complex. Pubmed 3.723E-16 1.186E-13 9.430E-13 5.930E-13 5 14
6 11748230 Purification of native survival of motor neurons complexes and identification of Gemin6 as a novel component. Pubmed 1.150E-15 3.054E-13 2.428E-12 1.833E-12 5 17
7 23221635 Implication of the SMN complex in the biogenesis and steady state level of the signal recognition particle. Pubmed 1.593E-15 3.625E-13 2.882E-12 2.537E-12 5 18
8 26908624 Monoubiquitination of survival motor neuron regulates its cellular localization and Cajal body integrity. Pubmed 9.946E-14 1.980E-11 1.575E-10 1.584E-10 4 8
9 23112048 Ubiquitin-specific protease 9x deubiquitinates and stabilizes the spinal muscular atrophy protein-survival motor neuron. Pubmed 1.790E-13 3.168E-11 2.519E-10 2.852E-10 4 9
10 10531003 Newly assembled snRNPs associate with coiled bodies before speckles, suggesting a nuclear snRNP maturation pathway. Pubmed 1.938E-12 3.087E-10 2.455E-9 3.087E-9 4 15
11 12361597 Coilin methylation regulates nuclear body formation. Pubmed 9.047E-12 1.310E-9 1.042E-8 1.441E-8 3 3
12 15130578 Why do cells need an assembly machine for RNA-protein complexes? Pubmed 1.038E-11 1.378E-9 1.095E-8 1.653E-8 4 22
13 20696395 Conserved beta-hairpin recognition by the GYF domains of Smy2 and GIGYF2 in mRNA surveillance and vesicular transport complexes. Pubmed 1.256E-11 1.539E-9 1.224E-8 2.001E-8 4 23
14 12420317 cAMP-dependent reorganization of the Cajal bodies and splicing machinery in cultured Schwann cells. Pubmed 3.618E-11 3.603E-9 2.864E-8 5.764E-8 3 4
15 11641277 Coilin forms the bridge between Cajal bodies and SMN, the spinal muscular atrophy protein. Pubmed 3.618E-11 3.603E-9 2.864E-8 5.764E-8 3 4
16 16434402 Gemin8 is a novel component of the survival motor neuron complex and functions in small nuclear ribonucleoprotein assembly. Pubmed 3.618E-11 3.603E-9 2.864E-8 5.764E-8 3 4
17 11470819 Residual Cajal bodies in coilin knockout mice fail to recruit Sm snRNPs and SMN, the spinal muscular atrophy gene product. Pubmed 9.045E-11 7.584E-9 6.030E-8 1.441E-7 3 5
18 21070772 Coilin interacts with Ku proteins and inhibits in vitro non-homologous DNA end joining. Pubmed 9.045E-11 7.584E-9 6.030E-8 1.441E-7 3 5
19 21072240 WRAP53 is essential for Cajal body formation and for targeting the survival of motor neuron complex to Cajal bodies. Pubmed 9.045E-11 7.584E-9 6.030E-8 1.441E-7 3 5
20 21300694 The COPI vesicle complex binds and moves with survival motor neuron within axons. Pubmed 1.809E-10 1.441E-8 1.145E-7 2.881E-7 3 6
21 10942426 Characterization of a nuclear 20S complex containing the survival of motor neurons (SMN) protein and a specific subset of spliceosomal Sm proteins. Pubmed 3.165E-10 2.292E-8 1.822E-7 5.042E-7 3 7
22 12095920 SMN, the spinal muscular atrophy protein, forms a pre-import snRNP complex with snurportin1 and importin beta. Pubmed 3.165E-10 2.292E-8 1.822E-7 5.042E-7 3 7
23 15848170 Unrip is a component of SMN complexes active in snRNP assembly. Pubmed 5.063E-10 3.507E-8 2.788E-7 8.066E-7 3 8
24 11509230 The survival of motor neurons (SMN) protein interacts with the snoRNP proteins fibrillarin and GAR1. Pubmed 7.594E-10 5.041E-8 4.008E-7 1.210E-6 3 9
25 16236758 The activity of the spinal muscular atrophy protein is regulated during development and cellular differentiation. Pubmed 1.085E-9 6.912E-8 5.496E-7 1.728E-6 3 10
26 26275778 NUFIP and the HSP90/R2TP chaperone bind the SMN complex and facilitate assembly of U4-specific proteins. Pubmed 1.491E-9 9.138E-8 7.265E-7 2.376E-6 3 11
27 10601333 Gemin3: A novel DEAD box protein that interacts with SMN, the spinal muscular atrophy gene product, and is a component of gems. Pubmed 1.988E-9 1.173E-7 9.327E-7 3.167E-6 3 12
28 11714716 Gemin5, a novel WD repeat protein component of the SMN complex that binds Sm proteins. Pubmed 2.584E-9 1.420E-7 1.129E-6 4.117E-6 3 13
29 11149922 A functional interaction between the survival motor neuron complex and RNA polymerase II. Pubmed 2.584E-9 1.420E-7 1.129E-6 4.117E-6 3 13
30 22190034 Global landscape of HIV-human protein complexes. Pubmed 2.907E-8 4.368E-7 3.473E-6 4.630E-5 5 457
31 9302277 Expression of the SMN gene, the spinal muscular atrophy determining gene, in the mammalian central nervous system. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
32 29066780 Survival Motor Neuron Protein is Released from Cells in Exosomes: A Potential Biomarker for Spinal Muscular Atrophy. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
33 12023986 Neurofilament accumulation at the motor endplate and lack of axonal sprouting in a spinal muscular atrophy mouse model. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
34 25911676 Astrocytes influence the severity of spinal muscular atrophy. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
35 29391529 Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
36 28069797 Oligodendrocyte development and CNS myelination are unaffected in a mouse model of severe spinal muscular atrophy. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
37 8838816 Structure and organization of the human survival motor neurone (SMN) gene. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
38 16481599 SMN mRNA and protein levels in peripheral blood: biomarkers for SMA clinical trials. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
39 29580671 Intron-retained transcripts of the spinal muscular atrophy genes, SMN1 and SMN2. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
40 23736298 The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
41 24152552 Genome-wide identification of mRNAs associated with the protein SMN whose depletion decreases their axonal localization. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
42 16449646 Splicing of a critical exon of human Survival Motor Neuron is regulated by a unique silencer element located in the last intron. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
43 20197730 Determination of SMN1 and SMN2 copy numbers in a Korean population using multiplex ligation-dependent probe amplification. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
44 18703124 Fugu rubripes and human survival motor neuron genes: structural and functional similarities in comparative genome studies. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
45 25347197 A comparison of three electrophysiological methods for the assessment of disease status in a mild spinal muscular atrophy mouse model. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
46 22930275 Physical exercise reduces cardiac defects in type 2 spinal muscular atrophy-like mice. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
47 25104390 Motor neuron disease. SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
48 22348054 Analysis of the fibroblast growth factor system reveals alterations in a mouse model of spinal muscular atrophy. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
49 27145767 Proteomic profile of embryonic stem cells with low survival motor neuron protein is consistent with developmental dysfunction. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
50 22884440 Modification of phenotype by SMN2 copy numbers in two Chinese families with SMN1 deletion in two continuous generations. Pubmed 4.936E-8 4.368E-7 3.473E-6 7.863E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 9 input genes in category / 539 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:GEMIN8 GEMIN8 interactions 7.385E-16 2.067E-13 1.420E-12 3.981E-13 6 28
2 int:GEMIN2 GEMIN2 interactions 9.595E-16 2.067E-13 1.420E-12 5.172E-13 7 79
3 int:SMN2 SMN2 interactions 1.151E-15 2.067E-13 1.420E-12 6.202E-13 7 81
4 int:RN7SL1 RN7SL1 interactions 2.191E-15 2.952E-13 2.027E-12 1.181E-12 5 10
5 int:SMN1 SMN1 interactions 3.057E-15 3.295E-13 2.263E-12 1.648E-12 8 210
6 int:GEMIN6 GEMIN6 interactions 4.551E-15 3.519E-13 2.417E-12 2.453E-12 6 37
7 int:DDX20 DDX20 interactions 4.571E-15 3.519E-13 2.417E-12 2.464E-12 7 98
8 int:GEMIN7 GEMIN7 interactions 1.192E-14 8.034E-13 5.518E-12 6.427E-12 6 43
9 int:GEMIN4 GEMIN4 interactions 1.445E-14 8.654E-13 5.944E-12 7.789E-12 7 115
10 int:RNU1-1 RNU1-1 interactions 2.608E-14 1.278E-12 8.776E-12 1.406E-11 5 15
11 int:RNU2-1 RNU2-1 interactions 2.608E-14 1.278E-12 8.776E-12 1.406E-11 5 15
12 int:SNRPB SNRPB interactions 6.538E-14 2.937E-12 2.017E-11 3.524E-11 7 142
13 int:GEMIN5 GEMIN5 interactions 1.295E-12 5.368E-11 3.687E-10 6.978E-10 6 91
14 int:STRAP STRAP interactions 3.708E-12 1.427E-10 9.803E-10 1.998E-9 6 108
15 int:SNRPE SNRPE interactions 2.753E-11 9.893E-10 6.794E-9 1.484E-8 6 150
16 int:SNRPF SNRPF interactions 4.075E-11 1.373E-9 9.428E-9 2.197E-8 6 160
17 int:SNRNP70 SNRNP70 interactions 3.041E-10 9.641E-9 6.621E-8 1.639E-7 6 223
18 int:SNRPG SNRPG interactions 2.162E-9 6.473E-8 4.446E-7 1.165E-6 5 127
19 int:PTPN9 PTPN9 interactions 2.792E-9 7.920E-8 5.440E-7 1.505E-6 4 40
20 int:SNRPD2 SNRPD2 interactions 5.179E-9 1.329E-7 9.129E-7 2.791E-6 5 151
21 int:SNRPD3 SNRPD3 interactions 5.179E-9 1.329E-7 9.129E-7 2.791E-6 5 151
22 int:LSM11 LSM11 interactions 4.473E-7 1.096E-5 7.527E-5 2.411E-4 3 32
23 int:SNRPD1 SNRPD1 interactions 6.535E-7 1.532E-5 1.052E-4 3.523E-4 4 153
24 int:SLX1B SLX1B interactions 1.191E-6 2.674E-5 1.837E-4 6.419E-4 3 44
25 int:P2RY12 P2RY12 interactions 3.385E-6 7.298E-5 5.012E-4 1.825E-3 3 62
26 int:DHX9 DHX9 interactions 5.658E-6 1.173E-4 8.055E-4 3.050E-3 4 263
27 int:LSM2 LSM2 interactions 6.270E-6 1.252E-4 8.596E-4 3.379E-3 3 76
28 int:DICER1 DICER1 interactions 8.180E-6 1.575E-4 1.081E-3 4.409E-3 3 83
29 int:GAR1 GAR1 interactions 1.079E-5 2.006E-4 1.378E-3 5.818E-3 3 91
30 int:SIGLECL1 SIGLECL1 interactions 1.308E-5 2.345E-4 1.611E-3 7.050E-3 3 97
31 int:COIL COIL interactions 1.349E-5 2.345E-4 1.611E-3 7.271E-3 3 98
32 int:GIGYF2 GIGYF2 interactions 2.014E-5 3.393E-4 2.330E-3 1.086E-2 3 112
33 int:FUBP1 FUBP1 interactions 2.180E-5 3.561E-4 2.446E-3 1.175E-2 3 115
34 int:NUFIP1 NUFIP1 interactions 2.296E-5 3.640E-4 2.500E-3 1.237E-2 3 117
35 int:WDYHV1 WDYHV1 interactions 5.219E-5 8.037E-4 5.520E-3 2.813E-2 3 154
36 int:KLHL8 KLHL8 interactions 5.781E-5 8.655E-4 5.944E-3 3.116E-2 2 23
37 int:USP9X USP9X interactions 7.506E-5 1.093E-3 7.510E-3 4.046E-2 3 174
38 int:ITCH ITCH interactions 1.021E-4 1.448E-3 9.947E-3
5.504E-2
 3 193
39 int:SNUPN SNUPN interactions 1.203E-4 1.663E-3 1.142E-2
6.485E-2
 2 33
40 int:STXBP2 STXBP2 interactions 1.278E-4 1.722E-3 1.183E-2
6.889E-2
 2 34
41 int:POP7 POP7 interactions 1.355E-4 1.782E-3 1.224E-2
7.304E-2
 2 35
42 int:STXBP3 STXBP3 interactions 1.600E-4 2.053E-3 1.410E-2
8.624E-2
 2 38
43 int:SRP54 SRP54 interactions 1.865E-4 2.337E-3 1.605E-2
1.005E-1
 2 41
44 int:LENG8 LENG8 interactions 1.957E-4 2.398E-3 1.647E-2
1.055E-1
 2 42
45 int:LSM7 LSM7 interactions 2.454E-4 2.876E-3 1.975E-2
1.323E-1
 2 47
46 int:PPIG PPIG interactions 2.454E-4 2.876E-3 1.975E-2
1.323E-1
 2 47
47 int:FBL FBL interactions 2.549E-4 2.923E-3 2.007E-2
1.374E-1
 3 263
48 int:LSM6 LSM6 interactions 3.124E-4 3.508E-3 2.409E-2
1.684E-1
 2 53
49 int:GDF9 GDF9 interactions 3.614E-4 3.896E-3 2.676E-2
1.948E-1
 2 57
50 int:NCKIPSD NCKIPSD interactions 3.614E-4 3.896E-3 2.676E-2
1.948E-1
 2 57
Show 45 more annotations

10: Cytoband [Display Chart] 9 input genes in category / 8 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 5q13.2 5q13.2 9.163E-5 7.330E-4 1.992E-3 7.330E-4 2 56
2 1p21.1-p13.2 1p21.1-p13.2 2.597E-4 1.039E-3 2.823E-3 2.077E-3 1 1
3 2p22.1 2p22.1 4.147E-3 1.106E-2 3.006E-2 3.318E-2 1 16
4 8q24 8q24 7.506E-3 1.501E-2 4.080E-2
6.005E-2
 1 29
5 Xp22.2 Xp22.2 1.085E-2 1.584E-2 4.306E-2
8.683E-2
 1 42
6 17q22 17q22 1.188E-2 1.584E-2 4.306E-2
9.506E-2
 1 46
7 19q13.32 19q13.32 2.033E-2 2.288E-2
6.217E-2
1.626E-1
 1 79
8 22q13.1 22q13.1 2.288E-2 2.288E-2
6.217E-2
1.830E-1
 1 89
Show 3 more annotations

11: Transcription Factor Binding Site [Display Chart] 3 input genes in category / 21 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 8 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1131 Gemins genenames.org 1.115E-9 6.692E-9 1.639E-8 6.692E-9 3 6
2 780 RNA binding motif containing|Tudor domain containing genenames.org 1.118E-4 3.354E-4 8.218E-4 6.709E-4 2 37
3 408 Argonaute/PIWI family genenames.org 3.513E-3 7.026E-3 1.721E-2 2.108E-2 1 8
4 629 Galectins genenames.org 6.578E-3 9.867E-3 2.417E-2 3.947E-2 1 15
5 499 DEAD-box helicases genenames.org 1.832E-2 2.199E-2
5.387E-2
1.099E-1
 1 42

13: Coexpression [Display Chart] 9 input genes in category / 867 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M123 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells, embryonical carcinomas and induced pluripotent cells). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.273E-6 2.838E-3 2.084E-2 2.838E-3 4 299
2 M7353 Genes down-regulated in HMC-1 (mast leukemia) cells incubated with the peptide ALL1 followed by treatment with: Cl-IB-MECA [PubChem=3035850] versus T cell membranes. MSigDB C7: Immunologic Signatures (v6.0) 5.144E-5 2.230E-2
1.637E-1
 4.460E-2 3 200
3 16188652-table1a Human StemCell Shaughnessy05 51genes GeneSigDB 1.567E-4 4.528E-2
3.325E-1
1.358E-1
 2 49

14: Coexpression Atlas [Display Chart] 9 input genes in category / 929 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 4 input genes in category / 46 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 9 input genes in category / 522 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-5688:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.064E-6 3.524E-4 2.409E-3 5.556E-4 3 170
2 hsa-miR-495-3p:Functional MTI Functional MTI miRTarbase 1.350E-6 3.524E-4 2.409E-3 7.048E-4 3 184
3 hsa-miR-5591-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.618E-5 2.199E-3 1.503E-2 8.444E-3 2 49
4 hsa-miR-660-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.685E-5 2.199E-3 1.503E-2 8.795E-3 2 50
5 hsa-miR-6509-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.494E-5 5.215E-3 3.565E-2 2.868E-2 2 90
6 hsa-miR-4436b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.995E-5 5.215E-3 3.565E-2 3.129E-2 2 94
7 hsa-miR-7-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.984E-4 1.164E-2
7.956E-2
1.035E-1
 2 171
8 hsa-miR-548l:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.007E-4 1.164E-2
7.956E-2
1.048E-1
 2 172
9 hsa-miR-4668-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.007E-4 1.164E-2
7.956E-2
1.048E-1
 2 172
10 hsa-miR-7-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.296E-4 1.198E-2
8.192E-2
1.198E-1
 2 184
11 hsa-miR-132-3p:Functional MTI Functional MTI miRTarbase 4.396E-4 1.987E-2
1.358E-1
2.294E-1
 2 255
12 hsa-miR-548n:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.568E-4 1.987E-2
1.358E-1
2.385E-1
 2 260
13 hsa-miR-212-3p:TargetScan hsa-miR-212-3p TargetScan 8.664E-4 3.230E-2
2.208E-1
4.522E-1
 2 359
14 hsa-miR-132-3p:TargetScan hsa-miR-132-3p TargetScan 8.664E-4 3.230E-2
2.208E-1
4.522E-1
 2 359
15 hsa-miR-222-3p:Functional MTI Functional MTI miRTarbase 1.041E-3 3.624E-2
2.477E-1
5.436E-1
 2 394
16 hsa-miR-520a-3p:Functional MTI Functional MTI miRTarbase 1.384E-3 4.239E-2
2.897E-1
7.224E-1
 2 455
17 TCCGTCC,MIR-184:MSigDB TCCGTCC,MIR-184:MSigDB MSigDB 1.494E-3 4.239E-2
2.897E-1
7.799E-1
 1 12
18 hsa-miR-184:TargetScan hsa-miR-184 TargetScan 2.240E-3 4.239E-2
2.897E-1
1.000E0
 1 18
19 TACGGGT,MIR-99B:MSigDB TACGGGT,MIR-99B:MSigDB MSigDB 2.862E-3 4.239E-2
2.897E-1
1.000E0
 1 23
20 TACGGGT,MIR-99A:MSigDB TACGGGT,MIR-99A:MSigDB MSigDB 2.862E-3 4.239E-2
2.897E-1
1.000E0
 1 23
21 TACGGGT,MIR-100:MSigDB TACGGGT,MIR-100:MSigDB MSigDB 2.862E-3 4.239E-2
2.897E-1
1.000E0
 1 23
22 hsa-miR-4785:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.235E-3 4.239E-2
2.897E-1
1.000E0
 1 26
23 hsa-miR-184:PITA hsa-miR-184:PITA TOP PITA 3.359E-3 4.239E-2
2.897E-1
1.000E0
 1 27
24 hsa-miR-3619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.856E-3 4.239E-2
2.897E-1
1.000E0
 1 31
25 hsa-miR-602:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.856E-3 4.239E-2
2.897E-1
1.000E0
 1 31
26 hsa-miR-6125:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.980E-3 4.239E-2
2.897E-1
1.000E0
 1 32
27 hsa-miR-100:PITA hsa-miR-100:PITA TOP PITA 4.104E-3 4.239E-2
2.897E-1
1.000E0
 1 33
28 hsa-miR-6755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.104E-3 4.239E-2
2.897E-1
1.000E0
 1 33
29 hsa-miR-99a:PITA hsa-miR-99a:PITA TOP PITA 4.104E-3 4.239E-2
2.897E-1
1.000E0
 1 33
30 hsa-miR-1911-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.104E-3 4.239E-2
2.897E-1
1.000E0
 1 33
31 hsa-miR-99b:PITA hsa-miR-99b:PITA TOP PITA 4.104E-3 4.239E-2
2.897E-1
1.000E0
 1 33
32 hsa-miR-4776-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.228E-3 4.239E-2
2.897E-1
1.000E0
 1 34
33 hsa-miR-542-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.228E-3 4.239E-2
2.897E-1
1.000E0
 1 34
34 hsa-miR-4256:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.352E-3 4.239E-2
2.897E-1
1.000E0
 1 35
35 hsa-miR-602:PITA hsa-miR-602:PITA TOP PITA 4.724E-3 4.239E-2
2.897E-1
1.000E0
 1 38
36 hsa-miR-4766-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.724E-3 4.239E-2
2.897E-1
1.000E0
 1 38
37 GGCAGAC,MIR-346:MSigDB GGCAGAC,MIR-346:MSigDB MSigDB 4.849E-3 4.239E-2
2.897E-1
1.000E0
 1 39
38 hsa-miR-6820-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 4.239E-2
2.897E-1
1.000E0
 1 42
39 hsa-miR-100-5p:TargetScan hsa-miR-100-5p TargetScan 5.345E-3 4.239E-2
2.897E-1
1.000E0
 1 43
40 hsa-miR-99a-5p:TargetScan hsa-miR-99a-5p TargetScan 5.345E-3 4.239E-2
2.897E-1
1.000E0
 1 43
41 hsa-miR-99b-5p:TargetScan hsa-miR-99b-5p TargetScan 5.345E-3 4.239E-2
2.897E-1
1.000E0
 1 43
42 hsa-miR-3649:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.345E-3 4.239E-2
2.897E-1
1.000E0
 1 43
43 hsa-miR-3197:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.593E-3 4.239E-2
2.897E-1
1.000E0
 1 45
44 hsa-miR-99b:mirSVR highEffct hsa-miR-99b:mirSVR conserved highEffect-0.5 MicroRNA.org 5.717E-3 4.239E-2
2.897E-1
1.000E0
 1 46
45 hsa-miR-6793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.088E-3 4.239E-2
2.897E-1
1.000E0
 1 49
46 hsa-miR-376a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.088E-3 4.239E-2
2.897E-1
1.000E0
 1 49
47 hsa-miR-6841-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.212E-3 4.239E-2
2.897E-1
1.000E0
 1 50
48 hsa-miR-1298-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.212E-3 4.239E-2
2.897E-1
1.000E0
 1 50
49 hsa-miR-4445-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.212E-3 4.239E-2
2.897E-1
1.000E0
 1 50
50 hsa-miR-6510-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.584E-3 4.239E-2
2.897E-1
1.000E0
 1 53
Show 45 more annotations

17: Drug [Display Chart] 9 input genes in category / 906 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000008447 MBTS Stitch 4.555E-15 3.053E-12 2.255E-11 4.127E-12 6 47
2 CID000011122 methyl-1,4-benzoquinone Stitch 6.739E-15 3.053E-12 2.255E-11 6.106E-12 6 50
3 CID005326396 I-bB Stitch 2.604E-14 7.863E-12 5.808E-11 2.359E-11 6 62
4 CID000003463 gemfibrozil Stitch 2.639E-13 5.978E-11 4.416E-10 2.391E-10 7 222
5 CID004369512 AC1NA07U Stitch 3.667E-13 6.645E-11 4.908E-10 3.322E-10 6 95
6 CID006432717 Ag I Stitch 4.610E-12 6.961E-10 5.142E-9 4.177E-9 5 49
7 CID000024563 silver iodide Stitch 1.106E-11 1.432E-9 1.058E-8 1.002E-8 5 58
8 CID000005297 NSC-14083 Stitch 4.616E-11 5.228E-9 3.862E-8 4.182E-8 6 210
9 CID000024572 lead arsenate Stitch 9.976E-11 1.004E-8 7.418E-8 9.038E-8 5 89
10 CID000005496 Dicon Stitch 1.248E-10 1.131E-8 8.355E-8 1.131E-7 5 93
11 CID006368594 AC1OC6D1 Stitch 2.205E-10 1.748E-8 1.291E-7 1.998E-7 5 104
12 CID000002142 amikacin sulphate Stitch 2.315E-10 1.748E-8 1.291E-7 2.098E-7 5 105
13 CID000445358 cyclohexen-1-amine Stitch 3.070E-10 2.140E-8 1.581E-7 2.782E-7 5 111
14 CID000003862 mimosine Stitch 5.607E-10 3.629E-8 2.680E-7 5.080E-7 5 125
15 CID000007965 cyclohexylammonium Stitch 1.273E-9 7.687E-8 5.678E-7 1.153E-6 5 147
16 CID000000899 N-acetylhexosamine Stitch 6.013E-9 3.405E-7 2.515E-6 5.448E-6 6 472
17 CID000001177 arabinosyluracil Stitch 1.041E-7 5.548E-6 4.098E-5 9.431E-5 5 354
18 CID000018622 glior Stitch 3.860E-6 1.943E-4 1.435E-3 3.497E-3 2 8
19 CID000001079 S-adenosylmethionine Stitch 6.797E-6 3.241E-4 2.394E-3 6.158E-3 4 355
20 CID003522585 MHDA Stitch 7.577E-6 3.269E-4 2.415E-3 6.865E-3 2 11
21 CID000001618 AC1L1BUX Stitch 7.577E-6 3.269E-4 2.415E-3 6.865E-3 2 11
22 CID000003718 indoprofen Stitch 9.090E-6 3.744E-4 2.765E-3 8.236E-3 2 12
23 CID000119498 C11122 Stitch 1.445E-5 5.693E-4 4.205E-3 1.309E-2 2 15
24 CID000062344 acridine orange Stitch 1.651E-5 6.234E-4 4.605E-3 1.496E-2 2 16
25 CID000135808 n-sulfo-2-aminotricarballylate Stitch 2.613E-5 9.468E-4 6.994E-3 2.367E-2 2 20
26 CID005287709 AC1NRA5C Stitch 3.529E-5 1.230E-3 9.084E-3 3.197E-2 3 174
27 CID000490573 AC1LALA3 Stitch 5.969E-5 2.003E-3 1.480E-2
5.408E-2
 2 30
28 CID006852127 Asn-SA Stitch 7.692E-5 2.489E-3 1.839E-2
6.969E-2
 2 34
29 CID000001225 SKF 82958 Stitch 1.015E-4 3.171E-3 2.342E-2
9.196E-2
 2 39
30 CID000005312 succinylacetone Stitch 1.294E-4 3.909E-3 2.888E-2
1.173E-1
 2 44
31 CID000445266 AC1L9HP6 Stitch 1.416E-4 4.137E-3 3.056E-2
1.283E-1
 2 46
32 CID006323417 1oz0 Stitch 1.608E-4 4.551E-3 3.362E-2
1.456E-1
 2 49
33 CID000001135 thymine Stitch 2.052E-4 5.634E-3 4.162E-2
1.859E-1
 3 315
34 CID000108001 3,5-dihydroxyphenylglycine Stitch 2.414E-4 6.433E-3 4.752E-2
2.187E-1
 2 60
35 CID006857724 platensimycin Stitch 2.662E-4 6.891E-3
5.090E-2
2.412E-1
 2 63
36 CID000080170 N-hydroxysuccinimide Stitch 2.834E-4 7.132E-3
5.268E-2
2.568E-1
 2 65
37 CID000007573 IPPD Stitch 3.011E-4 7.373E-3
5.447E-2
2.728E-1
 2 67
38 CID000002008 NSC 208734 Stitch 3.287E-4 7.394E-3
5.462E-2
2.978E-1
 2 70
39 CID000445522 H-Mn Stitch 3.382E-4 7.394E-3
5.462E-2
3.064E-1
 2 71
40 CID000001210 Tubocurarine,d Stitch 3.478E-4 7.394E-3
5.462E-2
3.151E-1
 2 72
41 CID014164528 L4 C Stitch 3.940E-4 7.394E-3
5.462E-2
3.570E-1
 1 1
42 ctd:C569212 9,10-dimethoxy-3,3-dimethyl-7,7a,13,13atetrahydro-3H-chromeno(3,4-b)pyrano(2,3-h)chromen-7-ol CTD 3.940E-4 7.394E-3
5.462E-2
3.570E-1
 1 1
43 CID000637997 3-pyrrolin-2-one Stitch 3.940E-4 7.394E-3
5.462E-2
3.570E-1
 1 1
44 CID004606265 2-amino-5-oxohexanamide Stitch 3.940E-4 7.394E-3
5.462E-2
3.570E-1
 1 1
45 CID012752071 methyl 4-bromothiophene-2-carboxylate Stitch 3.940E-4 7.394E-3
5.462E-2
3.570E-1
 1 1
46 CID000610409 4-bromo-2-thiophenecarboxylic acid Stitch 3.940E-4 7.394E-3
5.462E-2
3.570E-1
 1 1
47 CID009572782 [(E)-[amino-[methyl(nitroso)amino]methylidene]amino]-hydroxy-oxoazanium Stitch 3.977E-4 7.394E-3
5.462E-2
3.603E-1
 2 77
48 CID000449572 AC1L9N9H Stitch 3.977E-4 7.394E-3
5.462E-2
3.603E-1
 2 77
49 CID000004102 X 1497 Stitch 4.081E-4 7.394E-3
5.462E-2
3.697E-1
 2 78
50 CID003342293 AC1MOE8Y Stitch 4.081E-4 7.394E-3
5.462E-2
3.697E-1
 2 78
Show 45 more annotations

18: Disease [Display Chart] 9 input genes in category / 267 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0026847 Spinal Muscular Atrophy DisGeNET Curated 1.959E-10 5.229E-8 3.225E-7 5.229E-8 6 190
2 C0700595 Spinal Muscular Atrophies of Childhood DisGeNET Curated 2.742E-7 1.464E-5 9.029E-5 7.321E-5 2 2
3 C1838230 SPINAL MUSCULAR ATROPHY, TYPE IV DisGeNET Curated 2.742E-7 1.464E-5 9.029E-5 7.321E-5 2 2
4 OMIN:253400 SPINAL MUSCULAR ATROPHY, TYPE III; SMA3 OMIM 2.742E-7 1.464E-5 9.029E-5 7.321E-5 2 2
5 cv:C0152109 Kugelberg-Welander disease Clinical Variations 2.742E-7 1.464E-5 9.029E-5 7.321E-5 2 2
6 C0043116 HMN (Hereditary Motor Neuropathy) Proximal Type I DisGeNET Curated 3.442E-7 1.532E-5 9.445E-5 9.190E-5 3 27
7 C0393538 Muscular Atrophy, Spinal, Type II DisGeNET Curated 8.224E-7 3.137E-5 1.934E-4 2.196E-4 2 3
8 C0270816 epilepsy and migraine DisGeNET BeFree 1.644E-6 4.878E-5 3.008E-4 4.390E-4 2 4
9 C0393933 Pseudomyopathic myasthenia DisGeNET BeFree 1.644E-6 4.878E-5 3.008E-4 4.390E-4 2 4
10 C0264885 Myxoid transformation of mitral valve DisGeNET BeFree 2.740E-6 6.650E-5 4.100E-4 7.315E-4 2 5
11 C1708751 Low grade myofibroblastic sarcoma DisGeNET BeFree 2.740E-6 6.650E-5 4.100E-4 7.315E-4 2 5
12 C1834690 Spinal Muscular Atrophy, Childhood, Proximal, Autosomal Dominant DisGeNET Curated 4.108E-6 8.438E-5 5.203E-4 1.097E-3 2 6
13 C0205882 Infections, Parvovirus DisGeNET BeFree 4.108E-6 8.438E-5 5.203E-4 1.097E-3 2 6
14 C0242852 Proliferative vitreoretinopathy DisGeNET Curated 4.626E-6 8.823E-5 5.441E-4 1.235E-3 3 63
15 C0242429 Sore Throat DisGeNET BeFree 5.750E-6 9.031E-5 5.569E-4 1.535E-3 2 7
16 C0206622 Adenomyoma DisGeNET BeFree 5.750E-6 9.031E-5 5.569E-4 1.535E-3 2 7
17 C0037933 Spinal Diseases DisGeNET BeFree 5.750E-6 9.031E-5 5.569E-4 1.535E-3 2 7
18 C1865384 Amyotrophy, monomelic DisGeNET Curated 7.664E-6 1.077E-4 6.641E-4 2.046E-3 2 8
19 C1300347 Atypical polypoid adenomyoma DisGeNET BeFree 7.664E-6 1.077E-4 6.641E-4 2.046E-3 2 8
20 C0235259 Subcapsular cataract DisGeNET Curated 9.851E-6 1.253E-4 7.723E-4 2.630E-3 2 9
21 C0917981 Progressive Muscular Atrophy DisGeNET BeFree 9.851E-6 1.253E-4 7.723E-4 2.630E-3 2 9
22 C0265706 Gastroschisis DisGeNET Curated 1.231E-5 1.494E-4 9.213E-4 3.287E-3 2 10
23 C0393541 Distal Spinal Muscular Atrophy DisGeNET BeFree 1.504E-5 1.606E-4 9.906E-4 4.016E-3 2 11
24 C1266029 Enterochromaffin-like cell carcinoid DisGeNET BeFree 1.504E-5 1.606E-4 9.906E-4 4.016E-3 2 11
25 C0152109 Juvenile Spinal Muscular Atrophy DisGeNET Curated 1.504E-5 1.606E-4 9.906E-4 4.016E-3 2 11
26 C0027668 Neoplasms, Vascular Tissue DisGeNET Curated 1.804E-5 1.778E-4 1.096E-3 4.818E-3 2 12
27 C4024957 Proximal spinal muscular atrophy DisGeNET BeFree 1.804E-5 1.778E-4 1.096E-3 4.818E-3 2 12
28 C0730328 Central Serous Chorioretinopathy DisGeNET BeFree 1.864E-5 1.778E-4 1.096E-3 4.978E-3 3 100
29 C0848332 Spots on skin DisGeNET BeFree 2.107E-5 1.779E-4 1.097E-3 5.626E-3 4 336
30 C0270764 Motor Neuron Disease, Lower DisGeNET BeFree 2.132E-5 1.779E-4 1.097E-3 5.692E-3 2 13
31 C1306557 Chronic venous insufficiency DisGeNET BeFree 2.132E-5 1.779E-4 1.097E-3 5.692E-3 2 13
32 C0751870 Heredodegenerative Disorders, Nervous System DisGeNET Curated 2.132E-5 1.779E-4 1.097E-3 5.692E-3 2 13
33 C0085084 Motor Neuron Disease DisGeNET Curated 2.985E-5 2.415E-4 1.489E-3 7.971E-3 3 117
34 C0014060 Encephalitis, St. Louis DisGeNET BeFree 3.383E-5 2.657E-4 1.638E-3 9.034E-3 3 122
35 C1511934 Differentiating Neuroblastoma DisGeNET BeFree 4.176E-5 3.097E-4 1.910E-3 1.115E-2 2 18
36 C0007286 Carpal Tunnel Syndrome DisGeNET Curated 4.176E-5 3.097E-4 1.910E-3 1.115E-2 2 18
37 C0332878 Congenital joint contractures DisGeNET Curated 4.666E-5 3.367E-4 2.076E-3 1.246E-2 2 19
38 C0015230 Exanthema DisGeNET Curated 5.102E-5 3.585E-4 2.211E-3 1.362E-2 4 421
39 C1301959 Bulbar weakness DisGeNET Curated 5.727E-5 3.921E-4 2.418E-3 1.529E-2 2 21
40 C1292753 Primary Effusion Lymphoma DisGeNET BeFree 6.780E-5 4.490E-4 2.769E-3 1.810E-2 3 154
41 C0342782 Depletion of mitochondrial DNA DisGeNET BeFree 6.895E-5 4.490E-4 2.769E-3 1.841E-2 2 23
42 C0026896 Myasthenia Gravis DisGeNET Curated 8.938E-5 5.682E-4 3.504E-3 2.386E-2 3 169
43 C0013363 Dysautonomia DisGeNET Curated 1.105E-4 6.859E-4 4.229E-3 2.949E-2 2 29
44 C0151650 Renal fibrosis DisGeNET BeFree 1.226E-4 7.390E-4 4.557E-3 3.274E-2 3 188
45 C0013264 Muscular Dystrophy, Duchenne DisGeNET Curated 1.246E-4 7.390E-4 4.557E-3 3.326E-2 3 189
46 C0699743 Congenital muscular dystrophy (disorder) DisGeNET Curated 1.348E-4 7.826E-4 4.826E-3 3.600E-2 2 32
47 C0013312 Dupuytren Contracture DisGeNET Curated 1.435E-4 8.151E-4 5.026E-3 3.831E-2 2 33
48 C0235989 Renal interstitial fibrosis DisGeNET BeFree 1.524E-4 8.305E-4 5.121E-3 4.069E-2 2 34
49 C1959635 Parvovirus B19 (disease) DisGeNET BeFree 1.524E-4 8.305E-4 5.121E-3 4.069E-2 2 34
50 C0027430 Nasal Polyps DisGeNET Curated 1.562E-4 8.339E-4 5.142E-3 4.169E-2 3 204
Show 45 more annotations