Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc141_11, positive side

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1: GO: Molecular Function [Display Chart] 11 input genes in category / 34 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 5.132E-24 1.745E-22 7.186E-22 1.745E-22 9 35
2 GO:0019239 deaminase activity 1.062E-20 1.806E-19 7.437E-19 3.612E-19 8 35
3 GO:0004126 cytidine deaminase activity 6.618E-19 7.500E-18 3.089E-17 2.250E-17 6 9
4 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 5.267E-18 4.477E-17 1.844E-16 1.791E-16 9 148
5 GO:0047844 deoxycytidine deaminase activity 9.474E-7 5.367E-6 2.210E-5 3.221E-5 2 3
6 GO:0034547 N-cyclopropylmelamine deaminase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
7 GO:0043829 tRNA-specific adenosine-37 deaminase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
8 GO:0044682 archaeal-specific GTP cyclohydrolase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
9 GO:0052717 tRNA-specific adenosine-34 deaminase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
10 GO:0043723 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
11 GO:0034548 N-cyclopropylammeline deaminase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
12 GO:0034549 N-cyclopropylammelide alkylamino hydrolase activity 1.894E-6 5.367E-6 2.210E-5 6.440E-5 2 4
13 GO:0003933 GTP cyclohydrolase activity 3.156E-6 7.664E-6 3.156E-5 1.073E-4 2 5
14 GO:0008251 tRNA-specific adenosine deaminase activity 3.156E-6 7.664E-6 3.156E-5 1.073E-4 2 5
15 GO:0019238 cyclohydrolase activity 1.418E-5 3.214E-5 1.324E-4 4.821E-4 2 10
16 GO:0004000 adenosine deaminase activity 2.455E-5 5.218E-5 2.149E-4 8.348E-4 2 13
17 GO:0008829 dCTP deaminase activity 5.895E-4 1.113E-3 4.585E-3 2.004E-2 1 1
18 GO:0004131 cytosine deaminase activity 5.895E-4 1.113E-3 4.585E-3 2.004E-2 1 1
19 GO:0038187 pattern recognition receptor activity 9.978E-3 1.696E-2
6.986E-2
3.393E-1
 1 17
20 GO:0008329 signaling pattern recognition receptor activity 9.978E-3 1.696E-2
6.986E-2
3.393E-1
 1 17
21 GO:0017091 AU-rich element binding 1.348E-2 2.182E-2
8.987E-2
4.583E-1
 1 23
22 GO:0003887 DNA-directed DNA polymerase activity 1.639E-2 2.532E-2
1.043E-1
5.571E-1
 1 28
23 GO:0034061 DNA polymerase activity 2.737E-2 4.045E-2
1.666E-1
9.304E-1
 1 47
Show 18 more annotations

2: GO: Biological Process [Display Chart] 11 input genes in category / 212 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0009972 cytidine deamination 1.674E-18 1.183E-16 7.024E-16 3.550E-16 6 10
2 GO:0006216 cytidine catabolic process 1.674E-18 1.183E-16 7.024E-16 3.550E-16 6 10
3 GO:0046087 cytidine metabolic process 1.674E-18 1.183E-16 7.024E-16 3.550E-16 6 10
4 GO:0046133 pyrimidine ribonucleoside catabolic process 7.364E-18 3.903E-16 2.317E-15 1.561E-15 6 12
5 GO:0070383 DNA cytosine deamination 1.485E-16 6.298E-15 3.739E-14 3.149E-14 5 6
6 GO:0046135 pyrimidine nucleoside catabolic process 5.933E-16 2.096E-14 1.244E-13 1.258E-13 6 22
7 GO:0042454 ribonucleoside catabolic process 2.351E-15 7.120E-14 4.226E-13 4.984E-13 6 27
8 GO:0010528 regulation of transposition 3.117E-15 7.342E-14 4.358E-13 6.608E-13 5 9
9 GO:0010529 negative regulation of transposition 3.117E-15 7.342E-14 4.358E-13 6.608E-13 5 9
10 GO:0045006 DNA deamination 6.232E-15 1.321E-13 7.843E-13 1.321E-12 5 10
11 GO:0072529 pyrimidine-containing compound catabolic process 8.784E-15 1.693E-13 1.005E-12 1.862E-12 6 33
12 GO:0046131 pyrimidine ribonucleoside metabolic process 1.066E-14 1.884E-13 1.118E-12 2.261E-12 6 34
13 GO:0009164 nucleoside catabolic process 2.187E-14 3.566E-13 2.117E-12 4.636E-12 6 38
14 GO:0032196 transposition 4.946E-14 7.489E-13 4.446E-12 1.048E-11 5 14
15 GO:1901658 glycosyl compound catabolic process 5.584E-14 7.893E-13 4.685E-12 1.184E-11 6 44
16 GO:0006213 pyrimidine nucleoside metabolic process 1.608E-13 2.130E-12 1.264E-11 3.408E-11 6 52
17 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate 2.303E-12 2.777E-11 1.648E-10 4.883E-10 4 7
18 GO:0072527 pyrimidine-containing compound metabolic process 2.358E-12 2.777E-11 1.648E-10 4.998E-10 6 80
19 GO:1903901 negative regulation of viral life cycle 5.579E-12 6.225E-11 3.695E-10 1.183E-9 6 92
20 GO:0048525 negative regulation of viral process 6.795E-12 7.203E-11 4.276E-10 1.441E-9 6 95
21 GO:0045091 regulation of single stranded viral RNA replication via double stranded DNA intermediate 8.287E-12 8.366E-11 4.966E-10 1.757E-9 4 9
22 GO:0006304 DNA modification 9.895E-12 9.535E-11 5.660E-10 2.098E-9 6 101
23 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate 2.169E-11 1.999E-10 1.187E-9 4.598E-9 4 11
24 GO:0045071 negative regulation of viral genome replication 6.355E-11 5.614E-10 3.332E-9 1.347E-8 5 52
25 GO:0043901 negative regulation of multi-organism process 2.040E-10 1.709E-9 1.014E-8 4.325E-8 6 166
26 GO:0051607 defense response to virus 2.096E-10 1.709E-9 1.014E-8 4.443E-8 7 343
27 GO:0039694 viral RNA genome replication 2.542E-10 1.924E-9 1.142E-8 5.388E-8 4 19
28 GO:0039703 RNA replication 2.542E-10 1.924E-9 1.142E-8 5.388E-8 4 19
29 GO:1903900 regulation of viral life cycle 2.906E-10 2.124E-9 1.261E-8 6.161E-8 6 176
30 GO:1901136 carbohydrate derivative catabolic process 3.802E-10 2.687E-9 1.595E-8 8.060E-8 6 184
31 GO:0050792 regulation of viral process 4.470E-10 3.057E-9 1.815E-8 9.476E-8 6 189
32 GO:0045069 regulation of viral genome replication 5.834E-10 3.865E-9 2.294E-8 1.237E-7 5 80
33 GO:0009615 response to virus 9.832E-10 6.316E-9 3.749E-8 2.084E-7 7 428
34 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 1.117E-9 6.962E-9 4.133E-8 2.367E-7 6 220
35 GO:0019079 viral genome replication 2.009E-9 1.217E-8 7.225E-8 4.260E-7 5 102
36 GO:0016553 base conversion or substitution editing 1.285E-8 7.569E-8 4.493E-7 2.725E-6 3 9
37 GO:1901565 organonitrogen compound catabolic process 2.314E-8 1.326E-7 7.870E-7 4.905E-6 6 365
38 GO:0009119 ribonucleoside metabolic process 3.485E-8 1.944E-7 1.154E-6 7.388E-6 6 391
39 GO:0009116 nucleoside metabolic process 4.825E-8 2.623E-7 1.557E-6 1.023E-5 6 413
40 GO:0034655 nucleobase-containing compound catabolic process 5.183E-8 2.747E-7 1.631E-6 1.099E-5 6 418
41 GO:1901657 glycosyl compound metabolic process 6.566E-8 3.395E-7 2.015E-6 1.392E-5 6 435
42 GO:0019058 viral life cycle 7.716E-8 3.895E-7 2.312E-6 1.636E-5 6 447
43 GO:0044270 cellular nitrogen compound catabolic process 9.383E-8 4.626E-7 2.746E-6 1.989E-5 6 462
44 GO:0046700 heterocycle catabolic process 9.626E-8 4.638E-7 2.753E-6 2.041E-5 6 464
45 GO:0019439 aromatic compound catabolic process 1.092E-7 5.146E-7 3.054E-6 2.315E-5 6 474
46 GO:0080111 DNA demethylation 1.245E-7 5.738E-7 3.406E-6 2.639E-5 3 18
47 GO:0035510 DNA dealkylation 2.698E-7 1.217E-6 7.223E-6 5.719E-5 3 23
48 GO:0051053 negative regulation of DNA metabolic process 4.404E-7 1.945E-6 1.155E-5 9.336E-5 4 115
49 GO:0090310 negative regulation of methylation-dependent chromatin silencing 9.513E-7 4.116E-6 2.443E-5 2.017E-4 2 3
50 GO:0051052 regulation of DNA metabolic process 1.229E-6 5.209E-6 3.092E-5 2.604E-4 5 368
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 11 input genes in category / 6 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0000932 P-body 3.031E-10 1.818E-9 4.455E-9 1.818E-9 5 72
2 GO:0036464 cytoplasmic ribonucleoprotein granule 1.022E-8 2.684E-8 6.575E-8 6.134E-8 5 144
3 GO:0035770 ribonucleoprotein granule 1.342E-8 2.684E-8 6.575E-8 8.051E-8 5 152
4 GO:0030895 apolipoprotein B mRNA editing enzyme complex 9.080E-7 1.362E-6 3.337E-6 5.448E-6 2 3
5 GO:1990462 omegasome 2.882E-3 3.459E-3 8.474E-3 1.729E-2 1 5
6 GO:0000178 exosome (RNase complex) 1.206E-2 1.206E-2 2.954E-2
7.233E-2
 1 21
Show 1 more annotation

4: Human Phenotype [Display Chart] 3 input genes in category / 53 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 4 input genes in category / 141 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0004207 increased squamous cell carcinoma incidence 1.532E-4 1.168E-2
6.458E-2
 2.160E-2 2 53
2 MP:0013684 increased early germinal center B cell number 3.863E-4 1.168E-2
6.458E-2
5.447E-2
 1 1
3 MP:0013685 decreased late germinal center B cell number 3.863E-4 1.168E-2
6.458E-2
5.447E-2
 1 1
4 MP:0013682 abnormal late germinal center B cell number 3.863E-4 1.168E-2
6.458E-2
5.447E-2
 1 1
5 MP:0010300 increased skin tumor incidence 4.141E-4 1.168E-2
6.458E-2
5.839E-2
 2 87
6 MP:0012223 increased circulating prothrombin level 7.725E-4 1.361E-2
7.528E-2
1.089E-1
 1 2
7 MP:0012326 increased circulating antithrombin level 7.725E-4 1.361E-2
7.528E-2
1.089E-1
 1 2
8 MP:0013681 abnormal early germinal center B cell number 7.725E-4 1.361E-2
7.528E-2
1.089E-1
 1 2
9 MP:0008094 absent memory B cells 1.159E-3 1.485E-2
8.211E-2
1.634E-1
 1 3
10 MP:0012355 decreased prothrombin time 1.159E-3 1.485E-2
8.211E-2
1.634E-1
 1 3
11 MP:0012221 abnormal circulating prothrombin level 1.159E-3 1.485E-2
8.211E-2
1.634E-1
 1 3
12 MP:0010293 increased integument system tumor incidence 1.519E-3 1.675E-2
9.263E-2
2.141E-1
 2 167
13 MP:0012324 abnormal circulating antithrombin level 1.544E-3 1.675E-2
9.263E-2
2.178E-1
 1 4
14 MP:0012354 abnormal prothrombin time 2.316E-3 2.241E-2
1.239E-1
3.266E-1
 1 6
15 MP:0001202 skin photosensitivity 2.702E-3 2.241E-2
1.239E-1
3.809E-1
 1 7
16 MP:0008100 absent plasma cells 2.702E-3 2.241E-2
1.239E-1
3.809E-1
 1 7
17 MP:0008729 decreased memory B cell number 2.702E-3 2.241E-2
1.239E-1
3.809E-1
 1 7
18 MP:0009317 increased follicular lymphoma incidence 3.473E-3 2.720E-2
1.504E-1
4.896E-1
 1 9
19 MP:0001203 increased sensitivity to skin irradiation 5.013E-3 3.261E-2
1.803E-1
7.068E-1
 1 13
20 MP:0008093 abnormal memory B cell number 5.013E-3 3.261E-2
1.803E-1
7.068E-1
 1 13
21 MP:0002038 increased carcinoma incidence 5.381E-3 3.261E-2
1.803E-1
7.587E-1
 2 317
22 MP:0003975 increased circulating VLDL triglyceride level 5.398E-3 3.261E-2
1.803E-1
7.611E-1
 1 14
23 MP:0008192 abnormal germinal center B cell physiology 5.783E-3 3.261E-2
1.803E-1
8.153E-1
 1 15
24 MP:0008760 abnormal immunoglobulin heavy chain V(D)J recombination 5.783E-3 3.261E-2
1.803E-1
8.153E-1
 1 15
25 MP:0004501 increased incidence of tumors by UV-induction 5.783E-3 3.261E-2
1.803E-1
8.153E-1
 1 15
26 MP:0002440 abnormal memory B cell morphology 7.320E-3 3.610E-2
1.996E-1
1.000E0
 1 19
27 MP:0010377 abnormal gut flora balance 7.320E-3 3.610E-2
1.996E-1
1.000E0
 1 19
28 MP:0005607 decreased bleeding time 7.320E-3 3.610E-2
1.996E-1
1.000E0
 1 19
29 MP:0009704 increased skin squamous cell carcinoma incidence 7.704E-3 3.610E-2
1.996E-1
1.000E0
 1 20
30 MP:0004815 abnormal somatic hypermutation frequency 7.704E-3 3.610E-2
1.996E-1
1.000E0
 1 20
31 MP:0008755 abnormal immunoglobulin V(D)J recombination 8.089E-3 3.610E-2
1.996E-1
1.000E0
 1 21
32 MP:0002018 increased malignant tumor incidence 8.193E-3 3.610E-2
1.996E-1
1.000E0
 2 393
33 MP:0004030 induced chromosome breakage 9.624E-3 4.112E-2
2.274E-1
1.000E0
 1 25
34 MP:0002406 increased susceptibility to infection 1.062E-2 4.340E-2
2.400E-1
1.000E0
 2 449
35 MP:0006283 increased medulloblastoma incidence 1.077E-2 4.340E-2
2.400E-1
1.000E0
 1 28
36 MP:0000015 abnormal ear pigmentation 1.192E-2 4.473E-2
2.473E-1
1.000E0
 1 31
37 MP:0008098 decreased plasma cell number 1.231E-2 4.473E-2
2.473E-1
1.000E0
 1 32
38 MP:0004029 spontaneous chromosome breakage 1.231E-2 4.473E-2
2.473E-1
1.000E0
 1 32
39 MP:0030530 abnormal outer ear skin morphology 1.269E-2 4.473E-2
2.473E-1
1.000E0
 1 33
40 MP:0008177 increased germinal center B cell number 1.269E-2 4.473E-2
2.473E-1
1.000E0
 1 33
41 MP:0009277 increased brain tumor incidence 1.307E-2 4.495E-2
2.486E-1
1.000E0
 1 34
Show 36 more annotations

6: Domain [Display Chart] 11 input genes in category / 41 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS00903 CYT DCMP DEAMINASES 1 PROSITE 1.708E-27 3.502E-26 1.507E-25 7.003E-26 9 17
2 IPR002125 CMP dCMP Zn-bd InterPro 1.708E-27 3.502E-26 1.507E-25 7.003E-26 9 17
3 IPR013158 APOBEC N InterPro 2.172E-25 2.226E-24 9.578E-24 8.904E-24 8 12
4 PF08210 APOBEC N Pfam 2.172E-25 2.226E-24 9.578E-24 8.904E-24 8 12
5 IPR016192 APOBEC/CMP deaminase Zn-bd InterPro 1.317E-24 1.080E-23 4.647E-23 5.400E-23 8 14
6 PS51747 CYT DCMP DEAMINASES 2 PROSITE 2.822E-24 1.928E-23 8.297E-23 1.157E-22 8 15
7 IPR016193 Cytidine deaminase-like InterPro 1.066E-23 6.242E-23 2.686E-22 4.370E-22 8 17
8 IPR032917 TRIM5 InterPro 5.871E-4 2.407E-3 1.036E-2 2.407E-2 1 1
9 IPR006262 Cyt deam tetra InterPro 5.871E-4 2.407E-3 1.036E-2 2.407E-2 1 1
10 IPR017061 DNA pol eta/kappa InterPro 5.871E-4 2.407E-3 1.036E-2 2.407E-2 1 1
11 IPR017961 DNA pol Y-fam little finger InterPro 2.347E-3 6.414E-3 2.760E-2
9.621E-2
 1 4
12 3.30.1490.100 - Gene3D 2.347E-3 6.414E-3 2.760E-2
9.621E-2
 1 4
13 PF00817 IMS Pfam 2.347E-3 6.414E-3 2.760E-2
9.621E-2
 1 4
14 PS50173 UMUC PROSITE 2.347E-3 6.414E-3 2.760E-2
9.621E-2
 1 4
15 PF11799 IMS C Pfam 2.347E-3 6.414E-3 2.760E-2
9.621E-2
 1 4
16 PF00383 dCMP cyt deam 1 Pfam 2.933E-3 7.515E-3 3.234E-2
1.202E-1
 1 5
17 IPR001126 UmuC InterPro 3.518E-3 8.485E-3 3.651E-2
1.442E-1
 1 6
18 IPR006121 HMA dom InterPro 4.103E-3 9.347E-3 4.022E-2
1.682E-1
 1 7
19 PF13445 zf-RING UBOX Pfam 1.979E-2 4.056E-2
1.745E-1
8.113E-1
 1 34
20 IPR027370 Znf-RING LisH InterPro 1.979E-2 4.056E-2
1.745E-1
8.113E-1
 1 34
Show 15 more annotations

7: Pathway [Display Chart] 9 input genes in category / 42 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269705 Formation of the Editosome BioSystems: REACTOME 1.584E-11 3.327E-10 1.439E-9 6.653E-10 4 9
2 1269704 mRNA Editing: C to U Conversion BioSystems: REACTOME 1.584E-11 3.327E-10 1.439E-9 6.653E-10 4 9
3 1269703 mRNA Editing BioSystems: REACTOME 4.146E-11 5.805E-10 2.512E-9 1.741E-9 4 11
4 P02774 Salvage pyrimidine deoxyribonucleotides PantherDB 2.167E-3 1.517E-2
6.564E-2
9.103E-2
 1 3
5 782394 pyrimidine ribonucleosides salvage I BioSystems: BIOCYC 2.167E-3 1.517E-2
6.564E-2
9.103E-2
 1 3
6 142431 pyrimidine ribonucleosides degradation BioSystems: BIOCYC 2.167E-3 1.517E-2
6.564E-2
9.103E-2
 1 3
7 782401 pyrimidine deoxyribonucleosides degradation BioSystems: BIOCYC 3.610E-3 1.685E-2
7.289E-2
1.516E-1
 1 5
8 782392 pyrimidine deoxyribonucleosides salvage BioSystems: BIOCYC 3.610E-3 1.685E-2
7.289E-2
1.516E-1
 1 5
9 1269097 APOBEC3G mediated resistance to HIV-1 infection BioSystems: REACTOME 3.610E-3 1.685E-2
7.289E-2
1.516E-1
 1 5
10 782398 pyrimidine ribonucleosides degradation BioSystems: BIOCYC 4.330E-3 1.819E-2
7.869E-2
1.819E-1
 1 6
11 P02771 Pyrimidine Metabolism PantherDB 7.208E-3 2.752E-2
1.191E-1
3.027E-1
 1 10
12 1270140 Pyrimidine salvage reactions BioSystems: REACTOME 7.926E-3 2.774E-2
1.200E-1
3.329E-1
 1 11
13 PW:0000482 lipoprotein metabolic Pathway Ontology 9.361E-3 3.024E-2
1.309E-1
3.932E-1
 1 13
14 P02775 Salvage pyrimidine ribonucleotides PantherDB 1.079E-2 3.223E-2
1.395E-1
4.534E-1
 1 15
15 782391 superpathway of pyrimidine deoxyribonucleoside salvage BioSystems: BIOCYC 1.151E-2 3.223E-2
1.395E-1
4.834E-1
 1 16
16 1270371 Translesion Synthesis by POLH BioSystems: REACTOME 1.366E-2 3.585E-2
1.551E-1
5.735E-1
 1 19
17 SMP00046 Pyrimidine Metabolism SMPDB 1.793E-2 4.350E-2
1.882E-1
7.532E-1
 1 25
18 1270138 Pyrimidine metabolism BioSystems: REACTOME 1.864E-2 4.350E-2
1.882E-1
7.831E-1
 1 26
Show 13 more annotations

8: Pubmed [Display Chart] 11 input genes in category / 1835 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 12683974 Messenger RNA editing in mammals: new members of the APOBEC family seeking roles in the family business. Pubmed 4.631E-24 8.497E-21 6.876E-20 8.497E-21 7 11
2 22720156 APOBEC3 versus Retroviruses, Immunity versus Invasion: Clash of the Titans. Pubmed 4.094E-18 2.504E-15 2.026E-14 7.512E-15 5 6
3 22912627 Retroelements versus APOBEC3 family members: No great escape from the magnificent seven. Pubmed 4.094E-18 2.504E-15 2.026E-14 7.512E-15 5 6
4 21835787 Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1. Pubmed 1.433E-17 5.258E-15 4.255E-14 2.629E-14 5 7
5 23043100 The restriction factors of human immunodeficiency virus. Pubmed 1.433E-17 5.258E-15 4.255E-14 2.629E-14 5 7
6 24227842 APOBEC3 deaminases induce hypermutation in human papillomavirus 16 DNA upon beta interferon stimulation. Pubmed 3.820E-17 1.168E-14 9.453E-14 7.009E-14 5 8
7 20174454 Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS. Pubmed 1.718E-16 3.942E-14 3.190E-13 3.153E-13 5 10
8 23043103 Introduction to thematic minireview series: Understanding human immunodeficiency virus-host interactions at the biochemical level. Pubmed 1.718E-16 3.942E-14 3.190E-13 3.153E-13 5 10
9 22915799 HIV-1 replication and APOBEC3 antiviral activity are not regulated by P bodies. Pubmed 3.150E-16 6.423E-14 5.197E-13 5.780E-13 5 11
10 19649317 CEM-T4 cells do not lack an APOBEC3G cofactor. Pubmed 3.723E-15 4.879E-13 3.949E-12 6.831E-12 4 4
11 23097438 APOBEC3G restricts HIV-1 to a greater extent than APOBEC3F and APOBEC3DE in human primary CD4+ T cells and macrophages. Pubmed 3.723E-15 4.879E-13 3.949E-12 6.831E-12 4 4
12 22203821 Structural Features of Antiviral APOBEC3 Proteins are Linked to Their Functional Activities. Pubmed 3.723E-15 4.879E-13 3.949E-12 6.831E-12 4 4
13 19344514 A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR. Pubmed 3.723E-15 4.879E-13 3.949E-12 6.831E-12 4 4
14 27439715 APOBEC3 proteins can copackage and comutate HIV-1 genomes. Pubmed 3.723E-15 4.879E-13 3.949E-12 6.831E-12 4 4
15 25461536 A computational analysis of the structural determinants of APOBEC3's catalytic activity and vulnerability to HIV-1 Vif. Pubmed 1.861E-14 1.797E-12 1.455E-11 3.415E-11 4 5
16 18577210 HIV-1 Vif, APOBEC, and intrinsic immunity. Pubmed 1.861E-14 1.797E-12 1.455E-11 3.415E-11 4 5
17 18304004 The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements. Pubmed 1.861E-14 1.797E-12 1.455E-11 3.415E-11 4 5
18 25206352 Suppression of APOBEC3-mediated restriction of HIV-1 by Vif. Pubmed 1.861E-14 1.797E-12 1.455E-11 3.415E-11 4 5
19 25352838 AID and APOBECs span the gap between innate and adaptive immunity. Pubmed 1.861E-14 1.797E-12 1.455E-11 3.415E-11 4 5
20 22205746 Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors. Pubmed 5.582E-14 4.656E-12 3.768E-11 1.024E-10 4 6
21 23825473 Macaques as model hosts for studies of HIV-1 infection. Pubmed 5.582E-14 4.656E-12 3.768E-11 1.024E-10 4 6
22 24657093 Structure-guided analysis of the human APOBEC3-HIV restrictome. Pubmed 5.582E-14 4.656E-12 3.768E-11 1.024E-10 4 6
23 20062055 APOBEC3 proteins mediate the clearance of foreign DNA from human cells. Pubmed 1.302E-13 9.559E-12 7.736E-11 2.390E-10 4 7
24 11863358 An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22. Pubmed 1.302E-13 9.559E-12 7.736E-11 2.390E-10 4 7
25 19911124 APOBEC deaminases-mutases with defensive roles for immunity. Pubmed 1.302E-13 9.559E-12 7.736E-11 2.390E-10 4 7
26 19008196 APOBEC3G: an intracellular centurion. Pubmed 2.604E-13 1.770E-11 1.432E-10 4.779E-10 4 8
27 19038776 APOBEC proteins and intrinsic resistance to HIV-1 infection. Pubmed 2.604E-13 1.770E-11 1.432E-10 4.779E-10 4 8
28 25408426 The assembly of Vif ubiquitin E3 ligase for APOBEC3 degradation. Pubmed 4.687E-13 3.072E-11 2.486E-10 8.601E-10 4 9
29 12859895 Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif. Pubmed 1.294E-12 8.186E-11 6.624E-10 2.374E-9 5 49
30 24189052 Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all. Pubmed 8.843E-12 5.409E-10 4.377E-9 1.623E-8 4 17
31 20096141 Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeutics. Pubmed 1.137E-11 6.655E-10 5.386E-9 2.086E-8 4 18
32 24139399 HIV-1 Vif adaptation to human APOBEC3H haplotypes. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
33 25330146 APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
34 27289067 APOBEC3DE Antagonizes Hepatitis B Virus Restriction Factors APOBEC3F and APOBEC3G. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
35 17020885 Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
36 24942576 HIV-1 and HIV-2 Vif interact with human APOBEC3 proteins using completely different determinants. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
37 22807680 Endogenous origins of HIV-1 G-to-A hypermutation and restriction in the nonpermissive T cell line CEM2n. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
38 19561087 A portable hot spot recognition loop transfers sequence preferences from APOBEC family members to activation-induced cytidine deaminase. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
39 15269786 Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
40 22013041 The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
41 18976920 Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
42 17067930 Natural resistance to HIV infection: The Vif-APOBEC interaction. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
43 19939923 A single amino acid difference in human APOBEC3H variants determines HIV-1 Vif sensitivity. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
44 16648136 APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
45 21659520 Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
46 16378963 Restriction of foamy viruses by APOBEC cytidine deaminases. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
47 17303427 APOBEC-mediated viral restriction: not simply editing? Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
48 20538015 HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
49 25275135 Determinants of efficient degradation of APOBEC3 restriction factors by HIV-1 Vif. Pubmed 1.777E-11 6.655E-10 5.386E-9 3.261E-8 3 3
50 19535450 A patch of positively charged amino acids surrounding the human immunodeficiency virus type 1 Vif SLVx4Yx9Y motif influences its interaction with APOBEC3G. Pubmed 7.107E-11 2.461E-9 1.991E-8 1.304E-7 3 4
Show 45 more annotations

9: Interaction [Display Chart] 11 input genes in category / 315 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:APOBEC3F APOBEC3F interactions 9.808E-6 3.090E-3 1.956E-2 3.090E-3 2 8
2 int:DND1 DND1 interactions 2.728E-5 4.296E-3 2.720E-2 8.592E-3 2 13
3 int:ELAVL2 ELAVL2 interactions 4.938E-5 5.185E-3 3.283E-2 1.555E-2 3 121
4 int:KPNA2 KPNA2 interactions 3.060E-4 2.410E-2
1.526E-1
9.639E-2
 3 224
5 int:APOBEC3D APOBEC3D interactions 5.308E-4 3.344E-2
2.117E-1
1.672E-1
 2 56
6 int:APOBEC4 APOBEC4 interactions 1.242E-3 4.348E-2
2.753E-1
3.913E-1
 1 2
7 int:MKRN4P MKRN4P interactions 1.242E-3 4.348E-2
2.753E-1
3.913E-1
 1 2
8 int:APOBEC3H APOBEC3H interactions 1.242E-3 4.348E-2
2.753E-1
3.913E-1
 1 2
9 int:APOBEC2 APOBEC2 interactions 1.242E-3 4.348E-2
2.753E-1
3.913E-1
 1 2
Show 4 more annotations

10: Cytoband [Display Chart] 11 input genes in category / 8 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 22q13.1-q13.2 22q13.1-q13.2 5.492E-7 4.394E-6 1.194E-5 4.394E-6 2 4
2 22q13.1 22q13.1 2.660E-6 1.064E-5 2.892E-5 2.128E-5 3 89
3 1p36.2-p35 1p36.2-p35 6.346E-4 1.692E-3 4.600E-3 5.077E-3 1 2
4 12p13.1 12p13.1 6.961E-3 1.392E-2 3.784E-2
5.569E-2
 1 22
5 1q25.3 1q25.3 9.796E-3 1.567E-2 4.260E-2
7.837E-2
 1 31
6 11p15 11p15 1.482E-2 1.976E-2
5.370E-2
1.185E-1
 1 47
7 12p13 12p13 2.075E-2 2.371E-2
6.445E-2
1.660E-1
 1 66
8 6p21.1 6p21.1 2.572E-2 2.572E-2
6.991E-2
2.058E-1
 1 82
Show 3 more annotations

11: Transcription Factor Binding Site [Display Chart] 3 input genes in category / 22 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 10 input genes in category / 5 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 406 Apolipoprotein B mRNA editing enzyme catalytic subunits genenames.org 7.489E-26 3.744E-25 8.550E-25 3.744E-25 8 12
2 1125 Xeroderma pigmentosum complementation groups genenames.org 4.389E-3 1.097E-2 2.506E-2 2.195E-2 1 8
3 870 Minor histocompatibility antigens|FERM domain containing genenames.org 2.769E-2 4.615E-2
1.054E-1
1.384E-1
 1 51

13: Coexpression [Display Chart] 11 input genes in category / 778 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20460173-ImmPortAntimicrobials Human Immune Kong10 544genes ImmPort Antimicrobials GeneSigDB 4.913E-5 1.552E-2
1.123E-1
 3.822E-2 4 469
2 M6522 Genes up-regulated in epithelial cells (24h): untreated versus IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 9.396E-5 1.552E-2
1.123E-1
7.310E-2
 3 196
3 M3414 Genes down-regulated in comparison of microglia cells 1 h after stimulation with IFNG [GeneID=3458] versus microglia cells 24 h after the stimulation. MSigDB C7: Immunologic Signatures (v6.0) 9.976E-5 1.552E-2
1.123E-1
7.761E-2
 3 200
4 M4607 Genes up-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 10 versus CD25- T cells treated with IL4 [GeneID=3565] at 10 h. MSigDB C7: Immunologic Signatures (v6.0) 9.976E-5 1.552E-2
1.123E-1
7.761E-2
 3 200
5 M5921 Genes encoding components of the complement system, which is part of the innate immune system. MSigDB H: Hallmark Gene Sets (v6.0) 9.976E-5 1.552E-2
1.123E-1
7.761E-2
 3 200
6 14525759-Table2 Human Lung Singh04 53genes GeneSigDB 2.387E-4 3.096E-2
2.240E-1
1.857E-1
 2 49
Show 1 more annotation

14: Coexpression Atlas [Display Chart] 11 input genes in category / 641 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 6 input genes in category / 43 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 11 input genes in category / 158 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-99b:mirSVR lowEffct hsa-miR-99b:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 3.092E-4 2.440E-2
1.377E-1
 4.885E-2 2 173
2 hsa-miR-100:mirSVR lowEffct hsa-miR-100:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 4.167E-4 2.440E-2
1.377E-1
6.584E-2
 2 201
3 hsa-miR-99a:mirSVR lowEffct hsa-miR-99a:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 4.633E-4 2.440E-2
1.377E-1
7.320E-2
 2 212
4 hsa-miR-340*:mirSVR highEffct hsa-miR-340*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.456E-3 4.717E-2
2.662E-1
2.300E-1
 2 378
5 hsa-miR-4301:mirSVR highEffct hsa-miR-4301:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.595E-3 4.717E-2
2.662E-1
2.521E-1
 2 396
6 hsa-miR-383-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.791E-3 4.717E-2
2.662E-1
2.830E-1
 2 420
Show 1 more annotation

17: Drug [Display Chart] 11 input genes in category / 1759 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000091494 bromouridine Stitch 1.645E-17 2.893E-14 2.329E-13 2.893E-14 7 43
2 CID000000637 2'-dC Stitch 1.355E-15 1.191E-12 9.590E-12 2.383E-12 8 171
3 CID000000640 NSC23615 Stitch 3.627E-15 2.126E-12 1.712E-11 6.379E-12 8 193
4 CID000000596 Cytosar-U Stitch 7.387E-15 3.248E-12 2.615E-11 1.299E-11 9 399
5 CID000001174 uracil Stitch 5.338E-14 1.878E-11 1.512E-10 9.390E-11 8 269
6 CID000001177 arabinosyluracil Stitch 4.876E-13 1.112E-10 8.952E-10 8.577E-10 8 354
7 CID000000638 2-deoxyguanosine Stitch 4.984E-13 1.112E-10 8.952E-10 8.766E-10 7 178
8 CID000446904 homobiotin Stitch 5.058E-13 1.112E-10 8.952E-10 8.896E-10 6 76
9 CID000592814 N-cyclopropylammelide Stitch 2.035E-12 3.580E-10 2.882E-9 3.580E-9 4 8
10 CID006321196 C0761 Stitch 2.035E-12 3.580E-10 2.882E-9 3.580E-9 4 8
11 CID000000597 cytosine Stitch 2.844E-12 4.548E-10 3.661E-9 5.003E-9 8 441
12 CID000069605 5-fluoropyrimidine Stitch 1.405E-10 2.059E-8 1.657E-7 2.471E-7 4 20
13 CID000000624 ST013873 Stitch 2.390E-9 3.233E-7 2.603E-6 4.203E-6 5 129
14 CID000003454 ganciclovir Stitch 3.611E-9 4.537E-7 3.653E-6 6.352E-6 5 140
15 CID000003366 5-fluorocytosine Stitch 7.190E-9 8.432E-7 6.787E-6 1.265E-5 4 51
16 CID000073271 uracil-4-acetic acid Stitch 8.314E-8 9.141E-6 7.358E-5 1.463E-4 4 93
17 CID000451928 PMEI Stitch 1.672E-7 1.634E-5 1.316E-4 2.942E-4 3 24
18 CID000150856 5-fluorouridylate Stitch 1.672E-7 1.634E-5 1.316E-4 2.942E-4 3 24
19 CID000016861 5-fluorocytidine Stitch 1.900E-7 1.759E-5 1.416E-4 3.342E-4 3 25
20 CID000101494 5-bromo-2-pyrimidinone Stitch 2.109E-7 1.854E-5 1.493E-4 3.709E-4 2 2
21 CID000068401 pyrimidone Stitch 2.415E-7 2.023E-5 1.628E-4 4.248E-4 3 27
22 CID000050313 FIAU Stitch 2.704E-7 2.162E-5 1.741E-4 4.757E-4 3 28
23 CID000089105 CB1954 Stitch 3.015E-7 2.306E-5 1.856E-4 5.304E-4 3 29
24 CID000441083 N-isopropylammelide Stitch 6.324E-7 4.635E-5 3.731E-4 1.112E-3 2 3
25 CID000029243 tetrahydrouridine Stitch 6.945E-7 4.887E-5 3.934E-4 1.222E-3 3 38
26 CID000007898 2-cyanoacetamide Stitch 7.740E-7 5.237E-5 4.216E-4 1.362E-3 4 162
27 CID000131739 IAPE Stitch 1.264E-6 8.238E-5 6.631E-4 2.224E-3 2 4
28 CID000003893 lauric acid Stitch 1.557E-6 9.780E-5 7.873E-4 2.738E-3 4 193
29 CID000000968 orotidine5-phosphate Stitch 2.150E-6 1.304E-4 1.050E-3 3.782E-3 3 55
30 CID006442259 Invader Stitch 2.271E-6 1.308E-4 1.053E-3 3.995E-3 3 56
31 CID000001172 NSC20257 Stitch 2.305E-6 1.308E-4 1.053E-3 4.054E-3 4 213
32 CID000001056 dihydropyrimidine Stitch 2.662E-6 1.419E-4 1.142E-3 4.682E-3 3 59
33 CID000009260 pyrimidin Stitch 2.662E-6 1.419E-4 1.142E-3 4.682E-3 3 59
34 CID000000128 4-imidazolone-5-propionic acid Stitch 3.159E-6 1.635E-4 1.316E-3 5.558E-3 2 6
35 CID000439930 AC1L98C0 Stitch 3.740E-6 1.879E-4 1.513E-3 6.578E-3 3 66
36 CID000102672 formylglutamate Stitch 4.422E-6 2.161E-4 1.739E-3 7.779E-3 2 7
37 CID000001821 AF U Stitch 5.287E-6 2.447E-4 1.970E-3 9.299E-3 3 74
38 CID000000276 carbamate Stitch 5.287E-6 2.447E-4 1.970E-3 9.299E-3 3 74
39 CID000015759 p11-13 Stitch 5.505E-6 2.483E-4 1.999E-3 9.684E-3 3 75
40 CID006510265 FP-21399 Stitch 5.895E-6 2.529E-4 2.036E-3 1.037E-2 2 8
41 CID000270928 NSC123799 Stitch 5.895E-6 2.529E-4 2.036E-3 1.037E-2 2 8
42 CID000005704 x tt Stitch 6.945E-6 2.909E-4 2.342E-3 1.222E-2 3 81
43 CID006435890 AFFIRM Stitch 8.615E-6 3.524E-4 2.837E-3 1.515E-2 3 87
44 CID000001135 thymine Stitch 1.085E-5 4.251E-4 3.422E-3 1.909E-2 4 315
45 CID000000688 2'-deoxyuridine-5'-monophosphate Stitch 1.087E-5 4.251E-4 3.422E-3 1.913E-2 3 94
46 CID005275766 TAK-220 Stitch 1.388E-5 4.983E-4 4.011E-3 2.441E-2 2 12
47 CID004474230 AC1NBV46 Stitch 1.388E-5 4.983E-4 4.011E-3 2.441E-2 2 12
48 CID000483559 AMD3465 Stitch 1.388E-5 4.983E-4 4.011E-3 2.441E-2 2 12
49 CID000016553 hydroxyatrazine Stitch 1.388E-5 4.983E-4 4.011E-3 2.441E-2 2 12
50 CID000449515 G-F-P Stitch 1.696E-5 5.968E-4 4.804E-3 2.984E-2 3 109
Show 45 more annotations

18: Disease [Display Chart] 10 input genes in category / 193 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0035369 Retroviridae Infections DisGeNET BeFree 1.588E-7 3.064E-5 1.790E-4 3.064E-5 4 87
2 C0549410 Palmar-plantar erythrodysesthesia syndrome DisGeNET BeFree 1.880E-5 1.088E-3 6.356E-3 3.627E-3 2 11
3 C0852711 Sickle Cell Dactylitis DisGeNET BeFree 1.880E-5 1.088E-3 6.356E-3 3.627E-3 2 11
4 C1306589 Congenital dyserythropoietic anemia, type II DisGeNET Curated 2.255E-5 1.088E-3 6.356E-3 4.352E-3 2 12
5 C0002876 Congenital dyserythropoietic anemia DisGeNET Curated 4.638E-5 1.790E-3 1.046E-2 8.952E-3 2 17
6 C0085090 Lymphoma, AIDS-Related DisGeNET Curated 1.477E-4 4.752E-3 2.776E-2 2.851E-2 2 30
7 C0031069 Familial Mediterranean Fever DisGeNET Curated 3.969E-4 7.006E-3 4.093E-2
7.660E-2
 2 49
8 C0268138 Xeroderma Pigmentosum, Complementation Group D DisGeNET Curated 4.821E-4 7.006E-3 4.093E-2
9.305E-2
 2 54
9 C0398694 Selective immunoglobulin E deficiency DisGeNET BeFree 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
10 OMIN:605258 IMMUNODEFICIENCY WITH HYPER-IgM, TYPE 2 OMIM 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
11 OMIN:278750 XERODERMA PIGMENTOSUM, VARIANT TYPE; XPV OMIM 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
12 C1720956 Hyper-IgM Immunodeficiency Syndrome, Type 2 DisGeNET Curated 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
13 cv:C1720956 Immunodeficiency with hyper IgM type 2 Clinical Variations 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
14 C1275128 Autosomal recessive hyper-IgM syndrome DisGeNET BeFree 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
15 C0432328 Xeroderma pigmentosum, variant form DisGeNET Curated 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
16 C1302392 Adenoma of small intestine DisGeNET BeFree 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
17 cv:C1848410 Xeroderma pigmentosum, variant type Clinical Variations 6.171E-4 7.006E-3 4.093E-2
1.191E-1
 1 1
18 C0947622 Cholecystolithiasis DisGeNET BeFree 6.770E-4 7.259E-3 4.241E-2
1.307E-1
 2 64
19 C0850666 helicobacter pylori infection DisGeNET BeFree 7.672E-4 7.793E-3 4.553E-2
1.481E-1
 3 312
20 C0879615 Stromal Neoplasm DisGeNET BeFree 1.363E-3 1.315E-2
7.685E-2
2.631E-1
 2 91
21 C1863767 Light Fixation Seizure Syndrome DisGeNET BeFree 1.850E-3 1.420E-2
8.294E-2
3.571E-1
 1 3
22 C1567426 Unilateral Multicystic Dysplastic Kidney DisGeNET Curated 1.850E-3 1.420E-2
8.294E-2
3.571E-1
 1 3
23 C0854868 Non-Hodgkin's lymphoma transformed recurrent DisGeNET BeFree 1.850E-3 1.420E-2
8.294E-2
3.571E-1
 1 3
24 C1848410 Xeroderma pigmentosum, variant type DisGeNET Curated 1.850E-3 1.420E-2
8.294E-2
3.571E-1
 1 3
25 C1859923 Freckles in sun-exposed areas DisGeNET Curated 1.850E-3 1.420E-2
8.294E-2
3.571E-1
 1 3
26 C0008350 Cholelithiasis DisGeNET Curated 1.912E-3 1.420E-2
8.294E-2
3.691E-1
 2 108
27 C2350242 Osteoarthritis, Spine DisGeNET BeFree 2.466E-3 1.722E-2
1.006E-1
4.760E-1
 1 4
28 C0024530 Malaria DisGeNET Curated 2.499E-3 1.722E-2
1.006E-1
4.822E-1
 3 470
29 C0020445 Hypercholesterolemia, Familial DisGeNET Curated 3.011E-3 1.983E-2
1.158E-1
5.810E-1
 2 136
30 C0270962 Multi-core congenital myopathy DisGeNET BeFree 3.082E-3 1.983E-2
1.158E-1
5.948E-1
 1 5
31 C1850674 MINICORE MYOPATHY WITH EXTERNAL OPHTHALMOPLEGIA (disorder) DisGeNET Curated 3.697E-3 2.230E-2
1.303E-1
7.136E-1
 1 6
32 C2350344 Chronic Lung Injury DisGeNET BeFree 3.697E-3 2.230E-2
1.303E-1
7.136E-1
 1 6
33 C0001175 Acquired Immunodeficiency Syndrome DisGeNET Curated 4.189E-3 2.378E-2
1.389E-1
8.085E-1
 2 161
34 C0027947 Neutropenia DisGeNET Curated 4.240E-3 2.378E-2
1.389E-1
8.184E-1
 2 162
35 C0149517 Chronic tonsillitis DisGeNET BeFree 4.312E-3 2.378E-2
1.389E-1
8.323E-1
 1 7
36 C0014390 Entropion DisGeNET Curated 4.927E-3 2.642E-2
1.543E-1
9.509E-1
 1 8
37 C0553723 Squamous cell carcinoma of skin DisGeNET Curated 5.435E-3 2.815E-2
1.644E-1
1.000E0
 2 184
38 C2745948 Hyalinosis, Systemic DisGeNET Curated 5.542E-3 2.815E-2
1.644E-1
1.000E0
 1 9
39 C0268141 Xeroderma pigmentosum, group G DisGeNET Curated 6.156E-3 3.046E-2
1.780E-1
1.000E0
 1 10
40 C0237967 pediatric AIDS DisGeNET BeFree 6.769E-3 3.266E-2
1.908E-1
1.000E0
 1 11
41 C0524909 Hepatitis B, Chronic DisGeNET Curated 7.550E-3 3.470E-2
2.027E-1
1.000E0
 2 218
42 C0162429 Malnutrition DisGeNET Curated 7.550E-3 3.470E-2
2.027E-1
1.000E0
 2 218
43 C0272236 Hyperimmunoglobulin M syndrome DisGeNET Curated 7.996E-3 3.589E-2
2.097E-1
1.000E0
 1 13
44 C3826758 AIDS (Disease) DisGeNET BeFree 8.608E-3 3.692E-2
2.157E-1
1.000E0
 1 14
45 C1332051 AIDS-Related Non-Hodgkin Lymphoma DisGeNET BeFree 8.608E-3 3.692E-2
2.157E-1
1.000E0
 1 14
46 C0023530 Leukopenia DisGeNET Curated 8.799E-3 3.692E-2
2.157E-1
1.000E0
 2 236
47 C0037023 Sialadenitis DisGeNET BeFree 9.832E-3 3.952E-2
2.309E-1
1.000E0
 1 16
48 C1334634 Mature B-Cell Non-Hodgkin Lymphoma DisGeNET BeFree 9.832E-3 3.952E-2
2.309E-1
1.000E0
 1 16
49 C1290375 Mesothelioma (malignant, clinical disorder) (disorder) DisGeNET BeFree 1.006E-2 3.952E-2
2.309E-1
1.000E0
 2 253
50 C0343640 African Burkitt's lymphoma DisGeNET BeFree 1.044E-2 3.952E-2
2.309E-1
1.000E0
 1 17
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