Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc147_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 52 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043014 alpha-tubulin binding 3.367E-8 1.751E-6 7.946E-6 1.751E-6 3 29
2 GO:0048487 beta-tubulin binding 9.814E-8 2.552E-6 1.158E-5 5.103E-6 3 41
3 GO:0015631 tubulin binding 2.941E-7 5.098E-6 2.313E-5 1.529E-5 4 293
4 GO:0004859 phospholipase inhibitor activity 4.475E-6 5.817E-5 2.640E-4 2.327E-4 2 13
5 GO:0055102 lipase inhibitor activity 8.773E-6 9.124E-5 4.140E-4 4.562E-4 2 18
6 GO:0060961 phospholipase D inhibitor activity 2.679E-4 2.322E-3 1.054E-2 1.393E-2 1 1
7 GO:0008017 microtubule binding 1.280E-3 9.505E-3 4.313E-2
6.654E-2
2 214
8 GO:0050544 arachidonic acid binding 1.874E-3 1.139E-2
5.169E-2
9.747E-2
1 7
9 GO:0050543 icosatetraenoic acid binding 2.142E-3 1.139E-2
5.169E-2
1.114E-1
1 8
10 GO:1901567 fatty acid derivative binding 2.409E-3 1.139E-2
5.169E-2
1.253E-1
1 9
11 GO:0050542 icosanoid binding 2.409E-3 1.139E-2
5.169E-2
1.253E-1
1 9
12 GO:0048156 tau protein binding 3.746E-3 1.590E-2
7.214E-2
1.948E-1
1 14
13 GO:0004857 enzyme inhibitor activity 4.242E-3 1.590E-2
7.214E-2
2.206E-1
2 393
14 GO:0034185 apolipoprotein binding 4.280E-3 1.590E-2
7.214E-2
2.226E-1
1 16
15 GO:0036041 long-chain fatty acid binding 4.814E-3 1.669E-2
7.574E-2
2.503E-1
1 18
16 GO:0008198 ferrous iron binding 5.881E-3 1.799E-2
8.164E-2
3.058E-1
1 22
17 GO:0043274 phospholipase binding 5.881E-3 1.799E-2
8.164E-2
3.058E-1
1 22
18 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 6.681E-3 1.806E-2
8.198E-2
3.474E-1
1 25
19 GO:0071813 lipoprotein particle binding 6.948E-3 1.806E-2
8.198E-2
3.613E-1
1 26
20 GO:0071814 protein-lipid complex binding 6.948E-3 1.806E-2
8.198E-2
3.613E-1
1 26
21 GO:0051721 protein phosphatase 2A binding 9.344E-3 2.271E-2
1.031E-1
4.859E-1
1 35
22 GO:0051879 Hsp90 protein binding 9.610E-3 2.271E-2
1.031E-1
4.997E-1
1 36
23 GO:0019894 kinesin binding 1.120E-2 2.533E-2
1.150E-1
5.826E-1
1 42
24 GO:0043028 cysteine-type endopeptidase regulator activity involved in apoptotic process 1.227E-2 2.606E-2
1.183E-1
6.378E-1
1 46
25 GO:0005504 fatty acid binding 1.253E-2 2.606E-2
1.183E-1
6.516E-1
1 47
26 GO:0004869 cysteine-type endopeptidase inhibitor activity 1.545E-2 3.077E-2
1.396E-1
8.032E-1
1 58
27 GO:0005507 copper ion binding 1.597E-2 3.077E-2
1.396E-1
8.307E-1
1 60
28 GO:0004843 thiol-dependent ubiquitin-specific protease activity 1.994E-2 3.638E-2
1.651E-1
1.000E0
1 75
29 GO:0051219 phosphoprotein binding 2.073E-2 3.638E-2
1.651E-1
1.000E0
1 78
30 GO:0033293 monocarboxylic acid binding 2.099E-2 3.638E-2
1.651E-1
1.000E0
1 79
31 GO:0031072 heat shock protein binding 2.808E-2 4.328E-2
1.964E-1
1.000E0
1 106
32 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity 2.861E-2 4.328E-2
1.964E-1
1.000E0
1 108
33 GO:0101005 ubiquitinyl hydrolase activity 2.861E-2 4.328E-2
1.964E-1
1.000E0
1 108
34 GO:0043130 ubiquitin binding 2.861E-2 4.328E-2
1.964E-1
1.000E0
1 108
35 GO:0005200 structural constituent of cytoskeleton 2.913E-2 4.328E-2
1.964E-1
1.000E0
1 110
36 GO:0047485 protein N-terminus binding 3.096E-2 4.425E-2
2.008E-1
1.000E0
1 117
37 GO:0019783 ubiquitin-like protein-specific protease activity 3.148E-2 4.425E-2
2.008E-1
1.000E0
1 119
38 GO:0017124 SH3 domain binding 3.253E-2 4.451E-2
2.020E-1
1.000E0
1 123
39 GO:0032182 ubiquitin-like protein binding 3.357E-2 4.476E-2
2.031E-1
1.000E0
1 127
40 GO:0019903 protein phosphatase binding 3.748E-2 4.872E-2
2.211E-1
1.000E0
1 142
Show 35 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 466 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0008344 adult locomotory behavior 3.897E-9 1.816E-6 1.221E-5 1.816E-6 4 100
2 GO:0030534 adult behavior 3.328E-8 7.754E-6 5.213E-5 1.551E-5 4 170
3 GO:0007626 locomotory behavior 1.203E-7 1.869E-5 1.256E-4 5.606E-5 4 234
4 GO:0014059 regulation of dopamine secretion 1.869E-5 1.742E-3 1.171E-2 8.712E-3 2 26
5 GO:0014046 dopamine secretion 1.869E-5 1.742E-3 1.171E-2 8.712E-3 2 26
6 GO:0050808 synapse organization 2.575E-5 1.995E-3 1.341E-2 1.200E-2 3 258
7 GO:0031113 regulation of microtubule polymerization 3.035E-5 1.995E-3 1.341E-2 1.414E-2 2 33
8 GO:0042417 dopamine metabolic process 3.826E-5 1.995E-3 1.341E-2 1.783E-2 2 37
9 GO:0015872 dopamine transport 4.480E-5 1.995E-3 1.341E-2 2.088E-2 2 40
10 GO:0007628 adult walking behavior 4.709E-5 1.995E-3 1.341E-2 2.194E-2 2 41
11 GO:0090659 walking behavior 4.709E-5 1.995E-3 1.341E-2 2.194E-2 2 41
12 GO:0050804 modulation of chemical synaptic transmission 6.789E-5 2.597E-3 1.746E-2 3.164E-2 3 357
13 GO:0050433 regulation of catecholamine secretion 7.904E-5 2.597E-3 1.746E-2 3.683E-2 2 53
14 GO:0006584 catecholamine metabolic process 8.830E-5 2.597E-3 1.746E-2 4.115E-2 2 56
15 GO:0009712 catechol-containing compound metabolic process 8.830E-5 2.597E-3 1.746E-2 4.115E-2 2 56
16 GO:0050432 catecholamine secretion 9.150E-5 2.597E-3 1.746E-2 4.264E-2 2 57
17 GO:0046785 microtubule polymerization 9.476E-5 2.597E-3 1.746E-2 4.416E-2 2 58
18 GO:0031110 regulation of microtubule polymerization or depolymerization 1.049E-4 2.715E-3 1.825E-2 4.887E-2 2 61
19 GO:0046928 regulation of neurotransmitter secretion 1.155E-4 2.833E-3 1.904E-2
5.382E-2
2 64
20 GO:0051937 catecholamine transport 1.423E-4 3.314E-3 2.228E-2
6.629E-2
2 71
21 GO:0050805 negative regulation of synaptic transmission 1.631E-4 3.475E-3 2.336E-2
7.599E-2
2 76
22 GO:0051588 regulation of neurotransmitter transport 1.718E-4 3.475E-3 2.336E-2
8.005E-2
2 78
23 GO:0015844 monoamine transport 2.187E-4 3.475E-3 2.336E-2
1.019E-1
2 88
24 GO:0051952 regulation of amine transport 2.443E-4 3.475E-3 2.336E-2
1.138E-1
2 93
25 GO:0031109 microtubule polymerization or depolymerization 2.549E-4 3.475E-3 2.336E-2
1.188E-1
2 95
26 GO:0051622 negative regulation of norepinephrine uptake 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
27 GO:0051620 norepinephrine uptake 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
28 GO:0051585 negative regulation of dopamine uptake involved in synaptic transmission 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
29 GO:1903282 regulation of glutathione peroxidase activity 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
30 GO:2000470 positive regulation of peroxidase activity 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
31 GO:0070494 regulation of thrombin-activated receptor signaling pathway 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
32 GO:1903284 positive regulation of glutathione peroxidase activity 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
33 GO:0051621 regulation of norepinephrine uptake 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
34 GO:1903285 positive regulation of hydrogen peroxide catabolic process 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
35 GO:0070495 negative regulation of thrombin-activated receptor signaling pathway 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
36 GO:0051945 negative regulation of catecholamine uptake involved in synaptic transmission 2.685E-4 3.475E-3 2.336E-2
1.251E-1
1 1
37 GO:0015837 amine transport 2.825E-4 3.558E-3 2.392E-2
1.316E-1
2 100
38 GO:0018958 phenol-containing compound metabolic process 3.174E-4 3.892E-3 2.616E-2
1.479E-1
2 106
39 GO:0015696 ammonium transport 3.998E-4 4.778E-3 3.212E-2
1.863E-1
2 119
40 GO:0010726 positive regulation of hydrogen peroxide metabolic process 5.369E-4 6.102E-3 4.102E-2
2.502E-1
1 2
41 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone 5.369E-4 6.102E-3 4.102E-2
2.502E-1
1 2
42 GO:0070507 regulation of microtubule cytoskeleton organization 5.767E-4 6.399E-3 4.302E-2
2.687E-1
2 143
43 GO:0043524 negative regulation of neuron apoptotic process 7.123E-4 7.217E-3 4.851E-2
3.319E-1
2 159
44 GO:0007269 neurotransmitter secretion 7.483E-4 7.217E-3 4.851E-2
3.487E-1
2 163
45 GO:0099643 signal release from synapse 7.483E-4 7.217E-3 4.851E-2
3.487E-1
2 163
46 GO:0044070 regulation of anion transport 7.760E-4 7.217E-3 4.851E-2
3.616E-1
2 166
47 GO:0048167 regulation of synaptic plasticity 8.041E-4 7.217E-3 4.851E-2
3.747E-1
2 169
48 GO:1904715 negative regulation of chaperone-mediated autophagy 8.053E-4 7.217E-3 4.851E-2
3.753E-1
1 3
49 GO:0045914 negative regulation of catecholamine metabolic process 8.053E-4 7.217E-3 4.851E-2
3.753E-1
1 3
50 GO:2000468 regulation of peroxidase activity 8.053E-4 7.217E-3 4.851E-2
3.753E-1
1 3
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 54 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0033267 axon part 3.344E-7 1.508E-5 6.901E-5 1.806E-5 4 309
2 GO:0016234 inclusion body 5.586E-7 1.508E-5 6.901E-5 3.016E-5 3 74
3 GO:0030426 growth cone 8.443E-6 9.892E-5 4.526E-4 4.559E-4 3 182
4 GO:0043679 axon terminus 9.013E-6 9.892E-5 4.526E-4 4.867E-4 3 186
5 GO:0030427 site of polarized growth 9.159E-6 9.892E-5 4.526E-4 4.946E-4 3 187
6 GO:0044306 neuron projection terminus 1.104E-5 9.934E-5 4.545E-4 5.961E-4 3 199
7 GO:0043195 terminal bouton 3.383E-4 2.609E-3 1.194E-2 1.827E-2 2 112
8 GO:0045298 tubulin complex 1.311E-3 7.866E-3 3.599E-2
7.080E-2
1 5
9 GO:0097418 neurofibrillary tangle 1.311E-3 7.866E-3 3.599E-2
7.080E-2
1 5
10 GO:0098793 presynapse 3.079E-3 1.663E-2
7.608E-2
1.663E-1
2 341
11 GO:0031092 platelet alpha granule membrane 3.406E-3 1.672E-2
7.650E-2
1.839E-1
1 13
12 GO:0098794 postsynapse 5.282E-3 2.377E-2
1.087E-1
2.852E-1
2 449
13 GO:0005640 nuclear outer membrane 6.541E-3 2.717E-2
1.243E-1
3.532E-1
1 25
14 GO:0044295 axonal growth cone 7.585E-3 2.926E-2
1.339E-1
4.096E-1
1 29
15 GO:0045271 respiratory chain complex I 1.123E-2 3.567E-2
1.632E-1
6.064E-1
1 43
16 GO:0005747 mitochondrial respiratory chain complex I 1.123E-2 3.567E-2
1.632E-1
6.064E-1
1 43
17 GO:0030964 NADH dehydrogenase complex 1.123E-2 3.567E-2
1.632E-1
6.064E-1
1 43
Show 12 more annotations

4: Human Phenotype [Display Chart] 3 input genes in category / 178 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0002172 Postural instability 9.335E-7 7.230E-5 4.166E-4 1.662E-4 3 47
2 HP:0000741 Apathy 1.199E-6 7.230E-5 4.166E-4 2.134E-4 3 51
3 HP:0000745 Diminished motivation 1.349E-6 7.230E-5 4.166E-4 2.401E-4 3 53
4 HP:0007159 Fluctuations in consciousness 1.625E-6 7.230E-5 4.166E-4 2.892E-4 2 4
5 HP:0002185 Neurofibrillary tangles 2.515E-6 7.815E-5 4.503E-4 4.476E-4 3 65
6 HP:0002145 Frontotemporal dementia 2.634E-6 7.815E-5 4.503E-4 4.689E-4 3 66
7 HP:0100315 Lewy bodies 3.887E-6 9.885E-5 5.696E-4 6.920E-4 3 75
8 HP:0100256 Senile plaques 4.730E-6 1.052E-4 6.064E-4 8.419E-4 3 80
9 HP:0000711 Restlessness 7.230E-6 1.418E-4 8.173E-4 1.287E-3 3 92
10 HP:0100314 Cerebral inclusion bodies 7.969E-6 1.418E-4 8.173E-4 1.418E-3 3 95
11 HP:0000746 Delusions 1.079E-5 1.746E-4 1.006E-3 1.921E-3 3 105
12 HP:0002067 Bradykinesia 1.209E-5 1.793E-4 1.033E-3 2.151E-3 3 109
13 HP:0002511 Alzheimer disease 1.785E-5 2.445E-4 1.409E-3 3.178E-3 3 124
14 HP:0000709 Psychosis 2.157E-5 2.576E-4 1.485E-3 3.839E-3 3 132
15 HP:0045007 Abnormality of the substantia nigra 2.461E-5 2.576E-4 1.485E-3 4.380E-3 2 14
16 HP:0011960 Substantia nigra gliosis 2.461E-5 2.576E-4 1.485E-3 4.380E-3 2 14
17 HP:0002367 Visual hallucinations 2.461E-5 2.576E-4 1.485E-3 4.380E-3 2 14
18 HP:0002529 Neuronal loss in central nervous system 2.747E-5 2.717E-4 1.565E-3 4.890E-3 3 143
19 HP:0002354 Memory impairment 3.303E-5 3.095E-4 1.783E-3 5.880E-3 3 152
20 HP:0007311 Short stepped shuffling gait 3.676E-5 3.272E-4 1.885E-3 6.543E-3 2 17
21 HP:0001621 Weak voice 4.621E-5 3.917E-4 2.257E-3 8.225E-3 2 19
22 HP:0001300 Parkinsonism 5.880E-5 4.758E-4 2.741E-3 1.047E-2 3 184
23 HP:0000738 Hallucinations 6.274E-5 4.856E-4 2.798E-3 1.117E-2 3 188
24 HP:0002362 Shuffling gait 7.453E-5 5.527E-4 3.185E-3 1.327E-2 2 24
25 HP:0002180 Neurodegeneration 8.634E-5 6.148E-4 3.542E-3 1.537E-2 3 209
26 HP:0003470 Paralysis 1.214E-4 8.309E-4 4.788E-3 2.160E-2 3 234
27 HP:0002063 Rigidity 1.294E-4 8.528E-4 4.913E-3 2.302E-2 3 239
28 HP:0000514 Slow saccadic eye movements 1.424E-4 9.052E-4 5.216E-3 2.535E-2 2 33
29 HP:0002322 Resting tremor 1.513E-4 9.135E-4 5.264E-3 2.693E-2 2 34
30 HP:0002302 Abnormality of cognition 1.591E-4 9.135E-4 5.264E-3 2.832E-2 3 256
31 HP:0000726 Dementia 1.591E-4 9.135E-4 5.264E-3 2.832E-2 3 256
32 HP:0002418 Abnormality of midbrain morphology 2.319E-4 1.251E-3 7.207E-3 4.128E-2 2 42
33 HP:0000012 Urinary urgency 2.319E-4 1.251E-3 7.207E-3 4.128E-2 2 42
34 HP:0002071 Abnormality of extrapyramidal motor function 2.463E-4 1.290E-3 7.430E-3 4.385E-2 3 296
35 HP:0000713 Agitation 6.294E-4 3.151E-3 1.816E-2
1.120E-1
2 69
36 HP:0002439 Frontolimbic dementia 6.373E-4 3.151E-3 1.816E-2
1.134E-1
1 1
37 HP:0000570 Abnormal saccadic eye movements 7.439E-4 3.579E-3 2.062E-2
1.324E-1
2 75
38 HP:0001268 Mental deterioration 8.285E-4 3.782E-3 2.179E-2
1.475E-1
3 443
39 HP:0002489 Psychomotor regression 8.285E-4 3.782E-3 2.179E-2
1.475E-1
3 443
40 HP:0000298 Mask-like facies 1.071E-3 4.767E-3 2.747E-2
1.907E-1
2 90
41 HP:0001278 Orthostatic hypotension 1.219E-3 5.291E-3 3.049E-2
2.169E-1
2 96
42 HP:0002528 Granulovacuolar degeneration 1.274E-3 5.401E-3 3.112E-2
2.268E-1
1 2
43 HP:0002134 Abnormality of the basal ganglia 1.402E-3 5.784E-3 3.333E-2
2.496E-1
2 103
44 HP:0004673 Decreased facial expression 1.430E-3 5.784E-3 3.333E-2
2.545E-1
2 104
45 HP:0000751 Personality changes 1.513E-3 5.986E-3 3.449E-2
2.694E-1
2 107
46 HP:0002459 Dysautonomia 1.777E-3 6.848E-3 3.946E-2
3.164E-1
2 116
47 HP:0005346 Abnormal facial expression 1.808E-3 6.848E-3 3.946E-2
3.219E-1
2 117
48 HP:0002544 Retrocollis 1.911E-3 6.943E-3 4.000E-2
3.402E-1
1 3
49 HP:0002530 Axial dystonia 1.911E-3 6.943E-3 4.000E-2
3.402E-1
1 3
50 HP:0012407 Scissor gait 3.184E-3 1.134E-2
6.531E-2
5.668E-1
1 5
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 5 input genes in category / 238 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0003204 decreased neuron apoptosis 4.732E-6 9.649E-4 5.839E-3 1.126E-3 3 82
2 MP:0004077 abnormal striatum morphology 8.109E-6 9.649E-4 5.839E-3 1.930E-3 3 98
3 MP:0011452 decreased susceptibility to dopaminergic neuron neurotoxicity 1.452E-5 1.152E-3 6.971E-3 3.456E-3 2 13
4 MP:0006007 abnormal basal ganglion morphology 2.126E-5 1.265E-3 7.656E-3 5.061E-3 3 135
5 MP:0011448 decreased dopaminergic neuron number 5.127E-5 2.440E-3 1.477E-2 1.220E-2 2 24
6 MP:0008236 decreased susceptibility to neuronal excitotoxicity 1.103E-4 4.375E-3 2.647E-2 2.625E-2 2 35
7 MP:0006043 decreased apoptosis 1.456E-4 4.485E-3 2.714E-2 3.466E-2 3 257
8 MP:0012555 decreased cell death 1.507E-4 4.485E-3 2.714E-2 3.588E-2 3 260
9 MP:0003202 abnormal neuron apoptosis 1.705E-4 4.509E-3 2.729E-2 4.058E-2 3 271
10 MP:0003243 abnormal dopaminergic neuron morphology 2.450E-4 5.830E-3 3.528E-2
5.830E-2
2 52
11 MP:0005643 decreased dopamine level 2.946E-4 6.373E-3 3.857E-2
7.011E-2
2 57
12 MP:0014062 nervous system inclusion bodies 5.662E-4 1.123E-2
6.796E-2
1.348E-1
2 79
13 MP:0005405 axon degeneration 8.881E-4 1.626E-2
9.839E-2
2.114E-1
2 99
14 MP:0001905 abnormal dopamine level 9.796E-4 1.665E-2
1.008E-1
2.331E-1
2 104
15 MP:0001077 abnormal spinal nerve morphology 1.412E-3 2.088E-2
1.264E-1
3.360E-1
2 125
16 MP:0003354 astrocytosis 1.526E-3 2.088E-2
1.264E-1
3.631E-1
2 130
17 MP:0012065 increased astrocyte number 1.669E-3 2.088E-2
1.264E-1
3.971E-1
2 136
18 MP:0012064 abnormal astrocyte number 1.717E-3 2.088E-2
1.264E-1
4.088E-1
2 138
19 MP:0000746 weakness 1.817E-3 2.088E-2
1.264E-1
4.326E-1
2 142
20 MP:0000961 abnormal dorsal root ganglion morphology 1.894E-3 2.088E-2
1.264E-1
4.508E-1
2 145
21 MP:0003267 constipation 1.930E-3 2.088E-2
1.264E-1
4.594E-1
1 4
22 MP:0006003 abnormal large intestinal transit time 1.930E-3 2.088E-2
1.264E-1
4.594E-1
1 4
23 MP:0011479 abnormal catecholamine level 2.189E-3 2.265E-2
1.371E-1
5.210E-1
2 156
24 MP:0003214 neurofibrillary tangles 2.412E-3 2.392E-2
1.448E-1
5.742E-1
1 5
25 MP:0002792 abnormal retinal vasculature morphology 2.715E-3 2.585E-2
1.564E-1
6.463E-1
2 174
26 MP:0000969 abnormal nociceptor morphology 2.894E-3 2.649E-2
1.603E-1
6.889E-1
1 6
27 MP:0008282 enlarged hippocampus 3.376E-3 2.870E-2
1.737E-1
8.035E-1
1 7
28 MP:0010540 long stride length 3.376E-3 2.870E-2
1.737E-1
8.035E-1
1 7
29 MP:0002182 abnormal astrocyte morphology 3.537E-3 2.903E-2
1.757E-1
8.418E-1
2 199
30 MP:0003158 dysphagia 3.858E-3 3.060E-2
1.852E-1
9.181E-1
1 8
31 MP:0012306 enhanced spatial learning 4.339E-3 3.088E-2
1.869E-1
1.000E0
1 9
32 MP:0009317 increased follicular lymphoma incidence 4.339E-3 3.088E-2
1.869E-1
1.000E0
1 9
33 MP:0002183 gliosis 4.385E-3 3.088E-2
1.869E-1
1.000E0
2 222
34 MP:0002204 abnormal neurotransmitter level 4.502E-3 3.088E-2
1.869E-1
1.000E0
2 225
35 MP:0005404 abnormal axon morphology 4.541E-3 3.088E-2
1.869E-1
1.000E0
2 226
36 MP:0008503 abnormal spinal cord grey matter morphology 4.780E-3 3.101E-2
1.876E-1
1.000E0
2 232
37 MP:0002822 catalepsy 4.820E-3 3.101E-2
1.876E-1
1.000E0
1 10
38 MP:0000960 abnormal sensory ganglion morphology 5.751E-3 3.602E-2
2.180E-1
1.000E0
2 255
39 MP:0008493 alpha-synuclein inclusion body 6.263E-3 3.822E-2
2.313E-1
1.000E0
1 13
40 MP:0004250 tau protein deposits 6.743E-3 3.914E-2
2.369E-1
1.000E0
1 14
41 MP:0012314 enhanced learning 6.743E-3 3.914E-2
2.369E-1
1.000E0
1 14
42 MP:0008486 decreased muscle spindle number 7.223E-3 4.009E-2
2.426E-1
1.000E0
1 15
43 MP:0008874 decreased physiological sensitivity to xenobiotic 7.243E-3 4.009E-2
2.426E-1
1.000E0
2 287
44 MP:0010149 abnormal synaptic dopamine release 7.703E-3 4.074E-2
2.466E-1
1.000E0
1 16
45 MP:0002717 abnormal male preputial gland morphology 7.703E-3 4.074E-2
2.466E-1
1.000E0
1 16
46 MP:0009102 abnormal glans penis morphology 8.183E-3 4.075E-2
2.466E-1
1.000E0
1 17
47 MP:0004191 neuronal intranuclear inclusions 8.183E-3 4.075E-2
2.466E-1
1.000E0
1 17
48 MP:0006001 abnormal intestinal transit time 8.663E-3 4.075E-2
2.466E-1
1.000E0
1 18
49 MP:0003225 axonal dystrophy 8.663E-3 4.075E-2
2.466E-1
1.000E0
1 18
50 MP:0002948 abnormal neuron specification 9.142E-3 4.075E-2
2.466E-1
1.000E0
1 19
Show 45 more annotations

6: Domain [Display Chart] 5 input genes in category / 16 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR001058 Synuclein InterPro 9.126E-12 4.867E-11 1.645E-10 1.460E-10 3 3
2 1.10.287.700 - Gene3D 9.126E-12 4.867E-11 1.645E-10 1.460E-10 3 3
3 PF01387 Synuclein Pfam 9.126E-12 4.867E-11 1.645E-10 1.460E-10 3 3
4 IPR002955 Tau InterPro 2.669E-4 6.100E-4 2.062E-3 4.270E-3 1 1
5 IPR002461 Synuclein beta InterPro 2.669E-4 6.100E-4 2.062E-3 4.270E-3 1 1
6 IPR002462 Synuclein gamma InterPro 2.669E-4 6.100E-4 2.062E-3 4.270E-3 1 1
7 IPR002460 Synuclein alpha InterPro 2.669E-4 6.100E-4 2.062E-3 4.270E-3 1 1
8 PS00229 TAU MAP 1 PROSITE 8.005E-4 1.067E-3 3.608E-3 1.281E-2 1 3
9 IPR001084 MAP tubulin-bd rpt InterPro 8.005E-4 1.067E-3 3.608E-3 1.281E-2 1 3
10 PF00418 Tubulin-binding Pfam 8.005E-4 1.067E-3 3.608E-3 1.281E-2 1 3
11 IPR027324 MAP2/MAP4/Tau InterPro 8.005E-4 1.067E-3 3.608E-3 1.281E-2 1 3
12 PS51491 TAU MAP 2 PROSITE 8.005E-4 1.067E-3 3.608E-3 1.281E-2 1 3
13 3.40.532.10 - Gene3D 1.067E-3 1.067E-3 3.608E-3 1.707E-2 1 4
14 PS00140 UCH 1 PROSITE 1.067E-3 1.067E-3 3.608E-3 1.707E-2 1 4
15 IPR001578 Peptidase C12 UCH InterPro 1.067E-3 1.067E-3 3.608E-3 1.707E-2 1 4
16 PF01088 Peptidase C12 Pfam 1.067E-3 1.067E-3 3.608E-3 1.707E-2 1 4
Show 11 more annotations

7: Pathway [Display Chart] 5 input genes in category / 25 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 P00049 Parkinson disease PantherDB 3.263E-6 8.158E-5 3.113E-4 8.158E-5 3 87
2 PW:0000018 Parkinson disease Pathway Ontology 1.545E-5 1.931E-4 7.370E-4 3.863E-4 2 16
3 PW:0000015 Alzheimer disease Pathway Ontology 3.549E-5 2.957E-4 1.129E-3 8.872E-4 2 24
4 83097 Alzheimer's disease BioSystems: KEGG 1.825E-3 8.361E-3 3.191E-2 4.563E-2 2 171
5 PW:0000294 altered ubiquitin/proteasome degradation Pathway Ontology 2.007E-3 8.361E-3 3.191E-2
5.017E-2
1 5
6 PW:0000144 ubiquitin/proteasome degradation Pathway Ontology 2.007E-3 8.361E-3 3.191E-2
5.017E-2
1 5
7 M12718 Deregulation of CDK5 in Alzheimers Disease MSigDB C2 BIOCARTA (v6.0) 4.411E-3 1.447E-2
5.523E-2
1.103E-1
1 11
8 M13917 Role of Parkin in the Ubiquitin-Proteasomal Pathway MSigDB C2 BIOCARTA (v6.0) 4.811E-3 1.447E-2
5.523E-2
1.203E-1
1 12
9 1270289 Caspase-mediated cleavage of cytoskeletal proteins BioSystems: REACTOME 5.211E-3 1.447E-2
5.523E-2
1.303E-1
1 13
10 PW:0000007 mitogen activated protein kinase signaling Pathway Ontology 9.603E-3 2.401E-2
9.161E-2
2.401E-1
1 24
11 137980 Reelin signaling pathway BioSystems: Pathway Interaction Database 1.159E-2 2.459E-2
9.384E-2
2.899E-1
1 29
12 1457809 Synthesis of active ubiquitin: roles of E1 and E2 enzymes BioSystems: REACTOME 1.199E-2 2.459E-2
9.384E-2
2.998E-1
1 30
13 137913 Alpha-synuclein signaling BioSystems: Pathway Interaction Database 1.279E-2 2.459E-2
9.384E-2
3.197E-1
1 32
14 1270288 Apoptotic cleavage of cellular proteins BioSystems: REACTOME 1.557E-2 2.780E-2
1.061E-1
3.892E-1
1 39
15 M13494 Bioactive Peptide Induced Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 1.715E-2 2.859E-2
1.091E-1
4.288E-1
1 43
16 1270287 Apoptotic execution phase BioSystems: REACTOME 2.111E-2 3.298E-2
1.259E-1
5.277E-1
1 53
17 1457808 Protein ubiquitination BioSystems: REACTOME 2.466E-2 3.589E-2
1.369E-1
6.164E-1
1 62
18 137928 LPA receptor mediated events BioSystems: Pathway Interaction Database 2.584E-2 3.589E-2
1.369E-1
6.459E-1
1 65
Show 13 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 3975 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 28288128 α-Synuclein promotes dilation of the exocytotic fusion pore. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
2 17681534 Residual structure, backbone dynamics, and interactions within the synuclein family. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
3 11812782 Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
4 21117662 The synucleins are a family of redox-active copper binding proteins. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
5 20043104 Expression of alpha-, beta- and gamma-synuclein in colorectal cancer, and potential clinical significance in progression of the disease. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
6 15147505 Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
7 9750188 The synuclein family. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
8 20974939 αβγ-Synuclein triple knockout mice reveal age-dependent neuronal dysfunction. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
9 27733604 Monomeric Alpha-Synuclein Exerts a Physiological Role on Brain ATP Synthase. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
10 27614017 Combinational losses of synucleins reveal their differential requirements for compensating age-dependent alterations in motor behavior and dopamine metabolism. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
11 28052246 Synucleins Have Multiple Effects on Presynaptic Architecture. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
12 12783249 Expression of alpha-, beta-, and gamma-synuclein in glial tumors and medulloblastomas. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
13 14585981 Neurons expressing the highest levels of gamma-synuclein are unaffected by targeted inactivation of the gene. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
14 20697047 Association of alpha-, beta-, and gamma-Synuclein with diffuse lewy body disease. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
15 17222866 Relationships between the sequence of alpha-synuclein and its membrane affinity, fibrillization propensity, and yeast toxicity. Pubmed 1.077E-12 2.854E-10 2.530E-9 4.281E-9 3 3
16 15591046 beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein. Pubmed 4.308E-12 1.070E-9 9.488E-9 1.712E-8 3 4
17 21593311 Functional alterations to the nigrostriatal system in mice lacking all three members of the synuclein family. Pubmed 1.077E-11 2.518E-9 2.232E-8 4.281E-8 3 5
18 23077667 Genetic KCa3.1-deficiency produces locomotor hyperactivity and alterations in cerebral monoamine levels. Pubmed 2.154E-11 4.506E-9 3.995E-8 8.562E-8 3 6
19 18665422 Localization of synucleins in the mammalian cochlea. Pubmed 2.154E-11 4.506E-9 3.995E-8 8.562E-8 3 6
20 20798282 Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro. Pubmed 3.769E-11 7.491E-9 6.641E-8 1.498E-7 3 7
21 11698390 Tubulin seeds alpha-synuclein fibril formation. Pubmed 6.030E-11 1.141E-8 1.012E-7 2.397E-7 3 8
22 10852916 Synucleins are a novel class of substrates for G protein-coupled receptor kinases. Pubmed 1.292E-10 2.335E-8 2.070E-7 5.136E-7 3 10
23 17653558 Neuronal and glial accumulation of alpha- and beta-synucleins in human lipidoses. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
24 23319586 In vivo cross-linking reveals principally oligomeric forms of α-synuclein and β-synuclein in neurons and non-neural cells. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
25 10048491 Absence of mutation in the beta- and gamma-synuclein genes in familial autosomal dominant Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
26 17683088 Tau and alpha-synuclein in susceptibility to, and dementia in, Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
27 10464279 alpha-synuclein binds to Tau and stimulates the protein kinase A-catalyzed tau phosphorylation of serine residues 262 and 356. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
28 7558013 Assignment of human alpha-synuclein (SNCA) and beta-synuclein (SNCB) genes to chromosomes 4q21 and 5q35. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
29 15596612 Lewy bodies in the amygdala: increase of alpha-synuclein aggregates in neurodegenerative diseases with tau-based inclusions. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
30 16609851 Characterization of tau pathologies in gray and white matter of Guam parkinsonism-dementia complex. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
31 24430504 Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
32 17692832 An investigation into the lipid-binding properties of alpha-, beta- and gamma-synucleins in human brain and cerebrospinal fluid. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
33 15732111 Interaction of alpha-synuclein and tau genotypes in Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
34 19012742 Beta-synuclein occurs in vivo in lipid-associated oligomers and forms hetero-oligomers with alpha-synuclein. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
35 20805224 Seeded aggregation and toxicity of {alpha}-synuclein and tau: cellular models of neurodegenerative diseases. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
36 21391235 Independent and joint effects of the MAPT and SNCA genes in Parkinson disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
37 12070658 Concurrence of alpha-synuclein and tau brain pathology in the Contursi kindred. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
38 18333965 Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
39 21453448 Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
40 21054681 Lack of interaction of SNCA and MAPT genotypes in Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
41 22039514 Tau enhances α-synuclein aggregation and toxicity in cellular models of synucleinopathy. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
42 26776090 Variants in the SNCA gene associate with motor progression while variants in the MAPT gene associate with the severity of Parkinson's disease. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
43 21846727 E46K human alpha-synuclein transgenic mice develop Lewy-like and tau pathology associated with age-dependent, detrimental motor impairment. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
44 29054856 Levels of α- and β-synuclein regulate cellular susceptibility to toxicity from α-synuclein oligomers. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
45 17088319 Sensitivity of secondary structure propensities to sequence differences between alpha- and gamma-synuclein: implications for fibrillation. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
46 22104010 SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
47 29850516 Significant Changes in Plasma Alpha-Synuclein and Beta-Synuclein Levels in Male Children with Autism Spectrum Disorder. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
48 25960998 SNCA Gene, but Not MAPT, Influences Onset Age of Parkinson's Disease in Chinese and Australians. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
49 25495902 Differences in the binding of copper(I) to α- and β-synuclein. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
50 18436957 Molecular determinants of the aggregation behavior of alpha- and beta-synuclein. Pubmed 1.371E-8 6.987E-7 6.194E-6 5.450E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 399 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:GRK1 GRK1 interactions 2.378E-9 9.487E-7 6.231E-6 9.487E-7 3 12
2 int:GRK6 GRK6 interactions 9.855E-8 1.966E-5 1.291E-4 3.932E-5 3 39
3 int:DGUOK DGUOK interactions 6.688E-7 8.894E-5 5.841E-4 2.668E-4 3 73
4 int:DNAAF2 DNAAF2 interactions 9.871E-7 9.846E-5 6.466E-4 3.939E-4 3 83
5 int:NUFIP1 NUFIP1 interactions 2.787E-6 2.224E-4 1.460E-3 1.112E-3 3 117
6 int:SLC6A4 SLC6A4 interactions 5.800E-6 3.857E-4 2.533E-3 2.314E-3 2 14
7 int:SNCB SNCB interactions 8.665E-6 4.829E-4 3.171E-3 3.457E-3 2 17
8 int:GRK5 GRK5 interactions 9.683E-6 4.829E-4 3.171E-3 3.864E-3 3 177
9 int:PLK3 PLK3 interactions 1.089E-5 4.829E-4 3.171E-3 4.346E-3 2 19
10 int:SEPT4 SEPT4 interactions 1.611E-5 6.097E-4 4.004E-3 6.427E-3 2 23
11 int:MAPK8 MAPK8 interactions 1.687E-5 6.097E-4 4.004E-3 6.732E-3 3 213
12 int:SNCA SNCA interactions 1.834E-5 6.097E-4 4.004E-3 7.316E-3 3 219
13 int:HSPA1A HSPA1A interactions 4.605E-5 1.414E-3 9.283E-3 1.838E-2 3 298
14 int:SULT1A1 SULT1A1 interactions 6.009E-5 1.673E-3 1.098E-2 2.398E-2 2 44
15 int:ARMC1 ARMC1 interactions 6.288E-5 1.673E-3 1.098E-2 2.509E-2 2 45
16 int:AKT1 AKT1 interactions 1.050E-4 2.619E-3 1.720E-2 4.191E-2 3 393
17 int:FKBP4 FKBP4 interactions 2.761E-4 6.383E-3 4.192E-2
1.102E-1
2 94
18 int:PTK2B PTK2B interactions 2.879E-4 6.383E-3 4.192E-2
1.149E-1
2 96
19 int:CSNK1D CSNK1D interactions 3.062E-4 6.431E-3 4.223E-2
1.222E-1
2 99
20 int:MAPT MAPT interactions 5.194E-4 1.036E-2
6.805E-2
2.072E-1
2 129
21 int:SYK SYK interactions 5.941E-4 1.129E-2
7.413E-2
2.370E-1
2 138
22 int:HAX1 HAX1 interactions 6.556E-4 1.189E-2
7.809E-2
2.616E-1
2 145
23 int:AHCYL1 AHCYL1 interactions 8.073E-4 1.392E-2
9.143E-2
3.221E-1
2 161
24 int:PRKCD PRKCD interactions 8.890E-4 1.392E-2
9.143E-2
3.547E-1
2 169
25 int:TUBA1B TUBA1B interactions 8.995E-4 1.392E-2
9.143E-2
3.589E-1
2 170
26 int:SSSCA1 SSSCA1 interactions 9.206E-4 1.392E-2
9.143E-2
3.673E-1
2 172
27 int:USP9X USP9X interactions 9.420E-4 1.392E-2
9.143E-2
3.759E-1
2 174
28 int:SLC6A2 SLC6A2 interactions 1.412E-3 1.942E-2
1.275E-1
5.632E-1
1 5
29 int:COL25A1 COL25A1 interactions 1.412E-3 1.942E-2
1.275E-1
5.632E-1
1 5
30 int:CSNK1A1 CSNK1A1 interactions 1.652E-3 2.172E-2
1.426E-1
6.591E-1
2 231
31 int:PHKG1 PHKG1 interactions 1.694E-3 2.172E-2
1.426E-1
6.758E-1
1 6
32 int:UBB UBB interactions 1.782E-3 2.172E-2
1.426E-1
7.109E-1
2 240
33 int:DYNLL1 DYNLL1 interactions 1.796E-3 2.172E-2
1.426E-1
7.167E-1
2 241
34 int:YWHAH YWHAH interactions 1.886E-3 2.213E-2
1.453E-1
7.524E-1
2 247
35 int:FYN FYN interactions 1.993E-3 2.226E-2
1.462E-1
7.951E-1
2 254
36 int:PIN1 PIN1 interactions 2.008E-3 2.226E-2
1.462E-1
8.013E-1
2 255
37 int:LRRK2 LRRK2 interactions 2.071E-3 2.233E-2
1.467E-1
8.264E-1
2 259
38 int:MAPK3 MAPK3 interactions 2.232E-3 2.252E-2
1.479E-1
8.905E-1
2 269
39 int:ABCC8 ABCC8 interactions 2.258E-3 2.252E-2
1.479E-1
9.008E-1
1 8
40 int:CDC42EP2 CDC42EP2 interactions 2.258E-3 2.252E-2
1.479E-1
9.008E-1
1 8
41 int:PLK1 PLK1 interactions 2.382E-3 2.303E-2
1.512E-1
9.502E-1
2 278
42 int:MT-CO3 MT-CO3 interactions 2.540E-3 2.303E-2
1.512E-1
1.000E0
1 9
43 int:ARPP19 ARPP19 interactions 2.540E-3 2.303E-2
1.512E-1
1.000E0
1 9
44 int:NT5DC1 NT5DC1 interactions 2.540E-3 2.303E-2
1.512E-1
1.000E0
1 9
45 int:TUBA1A TUBA1A interactions 2.659E-3 2.345E-2
1.540E-1
1.000E0
2 294
46 int:ARHGAP15 ARHGAP15 interactions 2.822E-3 2.345E-2
1.540E-1
1.000E0
1 10
47 int:POGK POGK interactions 2.822E-3 2.345E-2
1.540E-1
1.000E0
1 10
48 int:BDH2 BDH2 interactions 2.822E-3 2.345E-2
1.540E-1
1.000E0
1 10
49 int:STUB1 STUB1 interactions 2.989E-3 2.360E-2
1.550E-1
1.000E0
2 312
50 int:ARHGEF40 ARHGEF40 interactions 3.103E-3 2.360E-2
1.550E-1
1.000E0
1 11
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 10q23.2-q23.3 10q23.2-q23.3 2.885E-4 1.442E-3 3.294E-3 1.442E-3 1 2
2 13q22.2 13q22.2 1.154E-3 2.884E-3 6.585E-3 5.768E-3 1 8
3 17q21.1 17q21.1 3.026E-3 3.458E-3 7.895E-3 1.513E-2 1 21
4 4q21 4q21 3.026E-3 3.458E-3 7.895E-3 1.513E-2 1 21
5 5q35 5q35 3.458E-3 3.458E-3 7.895E-3 1.729E-2 1 24

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 70 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 3 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 998 INO80 complex |Ubiquitin C-terminal hydrolases genenames.org 6.594E-4 1.978E-3 3.627E-3 1.978E-3 1 4
2 672 Parkinson disease associated genes|Ubiquitin C-terminal hydrolases genenames.org 2.636E-3 3.954E-3 7.249E-3 7.908E-3 1 16
3 694 Protein phosphatase 1 regulatory subunits genenames.org 2.955E-2 2.955E-2
5.418E-2
8.865E-2
1 181

13: Coexpression [Display Chart] 5 input genes in category / 441 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 15374961-Table2 Human Brain Freije04 44genes GeneSigDB 3.522E-5 1.553E-2
1.035E-1
1.553E-2 2 44
2 19252174-Table3 Human Leukemia Hernandez09 66genes GeneSigDB 7.729E-5 1.704E-2
1.136E-1
3.409E-2 2 65
3 M1544 Downregulated in the cerebellum of aged adult mice (30-month) vs young adult (5-month) MSigDB C2: CGP Curated Gene Sets (v6.0) 1.356E-4 1.993E-2
1.329E-1
5.979E-2
2 86
4 M15148 Genes down-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.139E-4 2.358E-2
1.572E-1
9.433E-2
2 108
5 M2395 Genes up-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.865E-4 3.581E-2
2.388E-1
2.145E-1
2 163
6 M5658 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. pneumoniae infection. MSigDB C7: Immunologic Signatures (v6.0) 5.668E-4 3.581E-2
2.388E-1
2.499E-1
2 176
7 M5656 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with acute influenza infection versus PBMC from patients with acute S. aureus infection. MSigDB C7: Immunologic Signatures (v6.0) 5.732E-4 3.581E-2
2.388E-1
2.528E-1
2 177
8 M9819 Genes down-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell IRF4-KO versus CD40L and IL-2 IL-4 IL-5 stimulated at day 1 B cell wildtype. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 3.581E-2
2.388E-1
3.159E-1
2 198
9 M9437 Genes up-regulated in comparison between in vitro derived induced T reg (iTreg) and converted ex iTreg. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.581E-2
2.388E-1
3.223E-1
2 200
10 20436685-ST5-2 Human Breast Pothuri10 228genes GeneSigDB 8.673E-4 3.825E-2
2.550E-1
3.825E-1
2 218
11 M10664 Genes up-regulated in MFCF-7 cells (breast cancer) upon stable autocrine expression of HG1 [GeneID=2688]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.268E-3 4.762E-2
3.175E-1
5.592E-1
2 264
12 18310505-TableS8 Human StemCell Matushansky08 297genes GeneSigDB 1.316E-3 4.762E-2
3.175E-1
5.803E-1
2 269
13 18855877-TableS2 Human Sarcoma Filion09 404genes GeneSigDB 1.655E-3 4.762E-2
3.175E-1
7.297E-1
2 302
14 M1204 Cluster 8: genes showing sustained pattern of down-regulation after knockdown of OPN [GeneID=6696] by RNAi in the NIH3T3 cells (fibroblasts) transformed by activated HRAS [GeneID=3265]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.728E-3 4.762E-2
3.175E-1
7.620E-1
1 8
15 M12889 Genes whose expression profile is specific to Cluster IIa of urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.728E-3 4.762E-2
3.175E-1
7.620E-1
1 8
16 M2498 Genes down-regulated in Calu-6 cells (lung cancer) at 1 h time point after TNF [GeneID=7124] treatment. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.728E-3 4.762E-2
3.175E-1
7.620E-1
1 8
Show 11 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 817 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Overall Top 200 Genes BrainMap 2.323E-8 1.643E-5 1.197E-4 1.898E-5 4 182
2 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Granule Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Granule Top 200 Genes BrainMap 8.324E-8 1.643E-5 1.197E-4 6.800E-5 4 250
3 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Cholinergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Cholinergic Top 200 Genes BrainMap 9.155E-8 1.643E-5 1.197E-4 7.480E-5 4 256
4 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Serotonergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Serotonergic Top 200 Genes BrainMap 1.203E-7 1.643E-5 1.197E-4 9.824E-5 4 274
5 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Inhibitory Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Inhibitory Top 200 Genes BrainMap 1.220E-7 1.643E-5 1.197E-4 9.969E-5 4 275
6 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Noradrenergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Noradrenergic Top 200 Genes BrainMap 1.408E-7 1.643E-5 1.197E-4 1.150E-4 4 285
7 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-peptidergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-peptidergic Top 200 Genes BrainMap 1.617E-7 1.643E-5 1.197E-4 1.321E-4 4 295
8 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Neurofilament Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Neurofilament Top 200 Genes BrainMap 1.753E-7 1.643E-5 1.197E-4 1.432E-4 4 301
9 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Excitatory Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Excitatory Top 200 Genes BrainMap 1.824E-7 1.643E-5 1.197E-4 1.490E-4 4 304
10 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Interneuron-selective Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Interneuron-selective Top 200 Genes BrainMap 2.103E-7 1.643E-5 1.197E-4 1.718E-4 4 315
11 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Dopaminergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Dopaminergic Top 200 Genes BrainMap 2.212E-7 1.643E-5 1.197E-4 1.808E-4 4 319
12 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Nitrergic enteric Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Nitrergic enteric Top 200 Genes BrainMap 2.993E-7 1.849E-5 1.347E-4 2.445E-4 4 344
13 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Peptidergic Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Peptidergic Top 200 Genes BrainMap 3.099E-7 1.849E-5 1.347E-4 2.532E-4 4 347
14 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype R-LM border Cck inter Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype R-LM border Cck inter Top 200 Genes BrainMap 3.171E-7 1.849E-5 1.347E-4 2.591E-4 4 349
15 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-border Cck inter Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Non-border Cck inter Top 200 Genes BrainMap 3.395E-7 1.849E-5 1.347E-4 2.774E-4 4 355
16 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligodendroglioma/4 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligodendroglioma/4 TCGA-Brain 6.717E-6 3.096E-4 2.255E-3 5.488E-3 3 193
17 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Astrocytoma/4 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Astrocytoma/4 TCGA-Brain 6.822E-6 3.096E-4 2.255E-3 5.573E-3 3 194
18 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligoastrocytoma/4 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligoastrocytoma/4 TCGA-Brain 6.822E-6 3.096E-4 2.255E-3 5.573E-3 3 194
19 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup7 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup7 Top 200 Genes BrainMap 9.949E-6 4.278E-4 3.116E-3 8.128E-3 3 220
20 StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells immature neurons immature neurons Subtype immature neurons s9 Top 200 Genes StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells immature neurons immature neurons Subtype immature neurons s9 Top 200 Genes StanfordMouse+HumanSingleCells 2.518E-5 1.029E-3 7.492E-3 2.057E-2 3 300
21 BrainMap BrainAtlas - Mouse McCarroll Neuron.inhibitory Neuron.inhibitory Subtype Inhibitory.subGroup2 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.inhibitory Neuron.inhibitory Subtype Inhibitory.subGroup2 Top 200 Genes BrainMap 3.111E-5 1.210E-3 8.815E-3 2.542E-2 3 322
22 StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells mature neurons mature neurons Subtype mature neurons s7 Top 200 Genes StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells mature neurons mature neurons Subtype mature neurons s7 Top 200 Genes StanfordMouse+HumanSingleCells 3.317E-5 1.232E-3 8.973E-3 2.710E-2 3 329
23 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Subtype eNb3 Top 40 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Subtype eNb3 Top 40 Genes GSE76381_ESMoleculeCountsPMLog2 8.152E-5 2.896E-3 2.109E-2
6.660E-2
2 63
24 6mo cortical organoids wt 6mo cortical organoids wt nan static Subtype 2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt nan static Subtype 2 Top 100 Genes 1.819E-4 6.193E-3 4.511E-2
1.486E-1
2 94
25 6mo cortical organoids wt 6mo cortical organoids wt Subtype 2 static Subtype 2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype 2 static Subtype 2 Top 100 Genes 1.898E-4 6.201E-3 4.517E-2
1.550E-1
2 96
26 6mo cortical organoids wt 6mo cortical organoids wt pan subtypes immature neuro precursors Overall Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt pan subtypes immature neuro precursors Overall Top 100 Genes 1.978E-4 6.214E-3 4.526E-2
1.616E-1
2 98
27 Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Collecting duct (CD)/late fetal/CD a Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Collecting duct (CD)/late fetal/CD a Fetal, Development 2.291E-4 6.931E-3
5.048E-2
1.871E-1
1 1
28 PCBC ratio EB from-plasmid vs EB from-ESC cfr-2X-p05 Embryoid Body Cells-method plasmid vs Embryoid Body Cells-method NA-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.723E-4 7.945E-3
5.787E-2
2.225E-1
2 115
29 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s7 immature neuro precursors Subtype immature neuro precursors s7 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s7 immature neuro precursors Subtype immature neuro precursors s7 Top 100 Genes 2.916E-4 8.076E-3
5.882E-2
2.382E-1
2 119
30 Sample Type by Project: Shred 1/TCGA-Kidney/Renal Cell Carcinoma/Kidney Chromophobe/7/2 Sample Type by Project: Shred 1/TCGA-Kidney/Renal Cell Carcinoma/Kidney Chromophobe/7/2 TCGA-Kidney 3.014E-4 8.076E-3
5.882E-2
2.463E-1
2 121
31 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s6 immature neuro precursors Subtype immature neuro precursors s6 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s6 immature neuro precursors Subtype immature neuro precursors s6 Top 100 Genes 3.064E-4 8.076E-3
5.882E-2
2.503E-1
2 122
32 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.1.6 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.1.6 Top 100 Genes 3.425E-4 8.744E-3
6.369E-2
2.798E-1
2 129
33 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eNb Top 40 GSE76381_ESMoleculeCountsPMLog2 3.532E-4 8.744E-3
6.369E-2
2.886E-1
2 131
34 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.1.5 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt mature-like mature-like Subtype M.1.5 Top 100 Genes 3.806E-4 9.146E-3
6.661E-2
3.110E-1
2 136
35 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup5/Prlr BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup5/Prlr BrainMap 4.090E-4 9.415E-3
6.857E-2
3.342E-1
2 141
36 Sample Type by Project: Shred 1/TCGA-Mesothelium/Mesothelioma /Diffuse Malignant/1/1 Sample Type by Project: Shred 1/TCGA-Mesothelium/Mesothelioma /Diffuse Malignant/1/1 TCGA-Mesothelium 4.148E-4 9.415E-3
6.857E-2
3.389E-1
2 142
37 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Pelvis Wilms NK cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Pelvis Wilms NK cell Adult, Development, and Cancer types 4.581E-4 9.960E-3
7.254E-2
3.742E-1
1 2
38 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup3/Gad2 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup3/Gad2 BrainMap 4.689E-4 9.960E-3
7.254E-2
3.831E-1
2 151
39 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s2 immature neuro precursors Subtype immature neuro precursors s2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s2 immature neuro precursors Subtype immature neuro precursors s2 Top 100 Genes 4.814E-4 9.960E-3
7.254E-2
3.933E-1
2 153
40 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s1 immature neuro precursors Subtype immature neuro precursors s1 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s1 immature neuro precursors Subtype immature neuro precursors s1 Top 100 Genes 4.876E-4 9.960E-3
7.254E-2
3.984E-1
2 154
41 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s11 immature neuro precursors Subtype immature neuro precursors s11 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s11 immature neuro precursors Subtype immature neuro precursors s11 Top 100 Genes 5.003E-4 9.970E-3
7.262E-2
4.088E-1
2 156
42 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s4 immature neuro precursors Subtype immature neuro precursors s4 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s4 immature neuro precursors Subtype immature neuro precursors s4 Top 100 Genes 5.799E-4 1.054E-2
7.680E-2
4.738E-1
2 168
43 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Phlda1 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Phlda1 BrainMap 6.077E-4 1.054E-2
7.680E-2
4.965E-1
2 172
44 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup5/Bcl11b BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup5/Bcl11b BrainMap 6.219E-4 1.054E-2
7.680E-2
5.081E-1
2 174
45 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Cpne5 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Cpne5 BrainMap 6.434E-4 1.054E-2
7.680E-2
5.256E-1
2 177
46 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s5 immature neuro precursors Subtype immature neuro precursors s5 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype immature neuro precursors s5 immature neuro precursors Subtype immature neuro precursors s5 Top 100 Genes 6.434E-4 1.054E-2
7.680E-2
5.256E-1
2 177
47 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Mural/Mural/Acta2/Acta2,Rgs5//Abcc9 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Mural/Mural/Acta2/Acta2,Rgs5//Abcc9 BrainMap 6.950E-4 1.054E-2
7.680E-2
5.678E-1
2 184
48 StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells static Subtype 2 Top 200 Genes StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells static Subtype 2 Top 200 Genes StanfordMouse+HumanSingleCells 6.950E-4 1.054E-2
7.680E-2
5.678E-1
2 184
49 StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells static Subtype 7 Top 200 Genes StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells static Subtype 7 Top 200 Genes StanfordMouse+HumanSingleCells 6.950E-4 1.054E-2
7.680E-2
5.678E-1
2 184
50 StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells static Subtype 8 Top 200 Genes StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells static Subtype 8 Top 200 Genes StanfordMouse+HumanSingleCells 7.101E-4 1.054E-2
7.680E-2
5.801E-1
2 186
Show 45 more annotations

15: Computational [Display Chart] 5 input genes in category / 34 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M8546 GNF2 MAPT Neighborhood of MAPT MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.615E-4 5.493E-3 2.262E-2 5.493E-3 2 41
2 M3373 GNF2 DNM1 Neighborhood of DNM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.144E-4 8.745E-3 3.602E-2 1.749E-2 2 73

16: MicroRNA [Display Chart] 5 input genes in category / 171 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-34c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.741E-5 9.817E-3
5.617E-2
9.817E-3 2 174
2 hsa-miR-4789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.626E-4 1.161E-2
6.643E-2
2.781E-2 2 293
3 hsa-miR-1324:PITA hsa-miR-1324:PITA TOP PITA 2.037E-4 1.161E-2
6.643E-2
3.483E-2 2 328
4 hsa-miR-615-3p:TargetScan hsa-miR-615-3p TargetScan 7.611E-4 2.827E-2
1.617E-1
1.302E-1
1 11
5 hsa-miR-6503-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.522E-3 2.827E-2
1.617E-1
2.602E-1
1 22
6 hsa-miR-4527:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.522E-3 2.827E-2
1.617E-1
2.602E-1
1 22
7 hsa-miR-4633-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.489E-3 2.827E-2
1.617E-1
4.257E-1
1 36
8 hsa-miR-3144-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.766E-3 2.827E-2
1.617E-1
4.729E-1
1 40
9 hsa-miR-875-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.042E-3 2.827E-2
1.617E-1
5.201E-1
1 44
10 hsa-miR-663:PITA hsa-miR-663:PITA TOP PITA 3.249E-3 2.827E-2
1.617E-1
5.556E-1
1 47
11 hsa-miR-548q:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 2.827E-2
1.617E-1
5.792E-1
1 49
12 hsa-miR-598:PITA hsa-miR-598:PITA TOP PITA 3.387E-3 2.827E-2
1.617E-1
5.792E-1
1 49
13 hsa-miR-7704:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.663E-3 2.827E-2
1.617E-1
6.264E-1
1 53
14 hsa-miR-3677-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.732E-3 2.827E-2
1.617E-1
6.382E-1
1 54
15 hsa-miR-3157-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.732E-3 2.827E-2
1.617E-1
6.382E-1
1 54
16 hsa-miR-4674:Functional MTI Functional MTI miRTarbase 3.732E-3 2.827E-2
1.617E-1
6.382E-1
1 54
17 hsa-miR-2117:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.939E-3 2.827E-2
1.617E-1
6.736E-1
1 57
18 hsa-miR-1915-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.215E-3 2.827E-2
1.617E-1
7.208E-1
1 61
19 hsa-miR-938:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.215E-3 2.827E-2
1.617E-1
7.208E-1
1 61
20 hsa-miR-6741-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.215E-3 2.827E-2
1.617E-1
7.208E-1
1 61
21 hsa-miR-4312:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 2.827E-2
1.617E-1
7.444E-1
1 63
22 hsa-miR-3134:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 2.827E-2
1.617E-1
7.444E-1
1 63
23 hsa-miR-606:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 2.827E-2
1.617E-1
7.444E-1
1 63
24 hsa-miR-532-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.422E-3 2.827E-2
1.617E-1
7.561E-1
1 64
25 hsa-miR-1249:mirSVR highEffct hsa-miR-1249:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.560E-3 2.827E-2
1.617E-1
7.797E-1
1 66
26 hsa-miR-6886-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.560E-3 2.827E-2
1.617E-1
7.797E-1
1 66
27 hsa-miR-615-5p:Functional MTI Functional MTI miRTarbase 4.836E-3 2.827E-2
1.617E-1
8.269E-1
1 70
28 hsa-miR-638:mirSVR highEffct hsa-miR-638:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.318E-3 2.827E-2
1.617E-1
9.094E-1
1 77
29 hsa-miR-874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.318E-3 2.827E-2
1.617E-1
9.094E-1
1 77
30 hsa-miR-7156-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.456E-3 2.827E-2
1.617E-1
9.330E-1
1 79
31 hsa-miR-4273:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.525E-3 2.827E-2
1.617E-1
9.448E-1
1 80
32 hsa-miR-4437:Functional MTI Functional MTI miRTarbase 5.732E-3 2.827E-2
1.617E-1
9.801E-1
1 83
33 hsa-miR-376c-3p:Functional MTI Functional MTI miRTarbase 5.801E-3 2.827E-2
1.617E-1
9.919E-1
1 84
34 hsa-miR-153-3p:Functional MTI Functional MTI miRTarbase 5.869E-3 2.827E-2
1.617E-1
1.000E0
1 85
35 hsa-miR-668:PITA hsa-miR-668:PITA TOP PITA 5.938E-3 2.827E-2
1.617E-1
1.000E0
1 86
36 hsa-miR-4773:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.558E-3 2.827E-2
1.617E-1
1.000E0
1 95
37 hsa-miR-6742-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.765E-3 2.827E-2
1.617E-1
1.000E0
1 98
38 hsa-miR-1296-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 2.827E-2
1.617E-1
1.000E0
1 99
39 hsa-miR-6781-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.971E-3 2.827E-2
1.617E-1
1.000E0
1 101
40 hsa-miR-2682-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.971E-3 2.827E-2
1.617E-1
1.000E0
1 101
41 hsa-miR-504:PITA hsa-miR-504:PITA TOP PITA 7.178E-3 2.827E-2
1.617E-1
1.000E0
1 104
42 hsa-miR-1229:PITA hsa-miR-1229:PITA TOP PITA 7.315E-3 2.827E-2
1.617E-1
1.000E0
1 106
43 hsa-miR-6507-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.315E-3 2.827E-2
1.617E-1
1.000E0
1 106
44 hsa-miR-921:PITA hsa-miR-921:PITA TOP PITA 7.590E-3 2.827E-2
1.617E-1
1.000E0
1 110
45 hsa-miR-514b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.866E-3 2.827E-2
1.617E-1
1.000E0
1 114
46 hsa-miR-513c-5p:Functional MTI Functional MTI miRTarbase 7.866E-3 2.827E-2
1.617E-1
1.000E0
1 114
47 hsa-miR-6801-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.866E-3 2.827E-2
1.617E-1
1.000E0
1 114
48 hsa-miR-3688-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.934E-3 2.827E-2
1.617E-1
1.000E0
1 115
49 hsa-miR-5093:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.141E-3 2.841E-2
1.626E-1
1.000E0
1 118
50 hsa-miR-668-3p:TargetScan hsa-miR-668-3p TargetScan 8.622E-3 2.861E-2
1.637E-1
1.000E0
1 125
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 2739 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000441767 sophoranone Stitch 2.014E-11 5.512E-8 4.682E-7 5.517E-8 3 4
2 CID000031170 indium phosphide Stitch 4.025E-11 5.512E-8 4.682E-7 1.102E-7 4 40
3 CID000324966 Nortryptoquivaline Stitch 2.621E-10 2.393E-7 2.033E-6 7.180E-7 4 63
4 CID000004347 1g4o Stitch 2.289E-9 1.568E-6 1.331E-5 6.271E-6 3 15
5 CID000447564 Ph-F Stitch 7.539E-9 4.066E-6 3.453E-5 2.065E-5 4 144
6 CID000100203 alkannin beta-hydroxyisovalerate Stitch 8.907E-9 4.066E-6 3.453E-5 2.440E-5 3 23
7 CID000556919 AC1LBF8B Stitch 1.157E-8 4.525E-6 3.843E-5 3.168E-5 3 25
8 CID000022251 thioflavin Stitch 4.963E-8 1.699E-5 1.443E-4 1.359E-4 3 40
9 CID000004624 6-OHDA Stitch 7.521E-8 2.289E-5 1.944E-4 2.060E-4 4 255
10 ctd:D052998 Microcystins CTD 1.897E-7 5.196E-5 4.413E-4 5.196E-4 3 62
11 CID003081320 Rim-1 Stitch 3.833E-7 9.543E-5 8.105E-4 1.050E-3 2 5
12 CID000007348 Sarkosyl Stitch 5.495E-7 1.254E-4 1.065E-3 1.505E-3 3 88
13 CID000086222 Spotlight Stitch 1.626E-6 3.373E-4 2.864E-3 4.453E-3 3 126
14 CID005359979 Direct Green 6 Stitch 1.724E-6 3.373E-4 2.864E-3 4.722E-3 2 10
15 CID000415676 NSC71948 Stitch 2.139E-6 3.906E-4 3.317E-3 5.858E-3 3 138
16 CID006436102 NF T Stitch 5.597E-6 8.128E-4 6.903E-3 1.533E-2 3 190
17 4656 UP Dipyridamole [58-32-2]; Up 200; 8uM; PC3; HT HG-U133A Broad Institute CMAP Up 6.144E-6 8.128E-4 6.903E-3 1.683E-2 3 196
18 7208 UP Levonordefrin [829-74-3]; Up 200; 21.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.144E-6 8.128E-4 6.903E-3 1.683E-2 3 196
19 2303 UP Nitrofurantoin [67-20-9]; Up 200; 16.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.431E-6 8.128E-4 6.903E-3 1.761E-2 3 199
20 2120 UP Tolfenamic acid [13710-19-5]; Up 200; 15.2uM; PC3; HT HG-U133A Broad Institute CMAP Up 6.431E-6 8.128E-4 6.903E-3 1.761E-2 3 199
21 4008 UP Rifampicin [13292-46-1]; Up 200; 4.8uM; PC3; HT HG-U133A Broad Institute CMAP Up 6.431E-6 8.128E-4 6.903E-3 1.761E-2 3 199
22 3385 DN Nizatidine [76963-41-2]; Down 200; 12uM; MCF7; HT HG-U133A Broad Institute CMAP Down 6.529E-6 8.128E-4 6.903E-3 1.788E-2 3 200
23 CID010184360 SMP2 000159 Stitch 7.273E-6 8.661E-4 7.355E-3 1.992E-2 2 20
24 CID000056494 fluorodopa F 18 Stitch 8.840E-6 1.009E-3 8.568E-3 2.421E-2 2 22
25 CID000005102 NSC115907 Stitch 1.535E-5 1.682E-3 1.428E-2 4.204E-2 3 266
26 CID000003007 amphetamine Stitch 1.867E-5 1.865E-3 1.584E-2
5.115E-2
3 284
27 CID000005572 trihexyphenidyl Stitch 1.897E-5 1.865E-3 1.584E-2
5.195E-2
2 32
28 ctd:D012524 Sarin CTD 1.907E-5 1.865E-3 1.584E-2
5.223E-2
3 286
29 ctd:D015632 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine CTD 2.594E-5 2.450E-3 2.081E-2
7.105E-2
3 317
30 ctd:C417521 SB 216763 CTD 3.289E-5 3.003E-3 2.550E-2
9.009E-2
2 42
31 CID000079784 tricine Stitch 4.128E-5 3.647E-3 3.097E-2
1.131E-1
2 47
32 ctd:C076996 27-hydroxycholesterol CTD 7.212E-5 6.173E-3
5.242E-2
1.975E-1
2 62
33 CID005461123 silicon Stitch 7.687E-5 6.206E-3
5.271E-2
2.105E-1
2 64
34 CID000000738 glutamin Stitch 7.925E-5 6.206E-3
5.271E-2
2.171E-1
3 461
35 CID000002936 AC1L1ET5 Stitch 7.930E-5 6.206E-3
5.271E-2
2.172E-1
2 65
36 CID000006051 4-aminoazobenzene Stitch 8.177E-5 6.222E-3
5.284E-2
2.240E-1
2 66
37 CID000234384 alph a- Stitch 8.941E-5 6.279E-3
5.333E-2
2.449E-1
2 69
38 CID000162602 dopamine quinone Stitch 8.941E-5 6.279E-3
5.333E-2
2.449E-1
2 69
39 CID000130300 paramethoxyphenyl-acetyl dehydroalanine Stitch 8.941E-5 6.279E-3
5.333E-2
2.449E-1
2 69
40 CID011963491 2b1g Stitch 9.469E-5 6.484E-3
5.507E-2
2.594E-1
2 71
41 ctd:D024505 Tocopherols CTD 1.114E-4 7.267E-3
6.172E-2
3.052E-1
2 77
42 CID000107904 bityrosine Stitch 1.114E-4 7.267E-3
6.172E-2
3.052E-1
2 77
43 CID000444453 1b-42 Stitch 1.234E-4 7.857E-3
6.673E-2
3.379E-1
2 81
44 CID000163786 AC1Q6G0L Stitch 2.189E-4 8.776E-3
7.453E-2
5.996E-1
1 1
45 ctd:C041573 stigmatellin CTD 2.189E-4 8.776E-3
7.453E-2
5.996E-1
1 1
46 ctd:D001375 Azaguanine CTD 2.189E-4 8.776E-3
7.453E-2
5.996E-1
1 1
47 ctd:D007832 Lasalocid CTD 2.189E-4 8.776E-3
7.453E-2
5.996E-1
1 1
48 ctd:C084924 1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline CTD 2.189E-4 8.776E-3
7.453E-2
5.996E-1
1 1
49 ctd:C100213 piericidin A CTD 2.189E-4 8.776E-3
7.453E-2
5.996E-1
1 1
50 CID000019688 norethisterone oenanthate Stitch 2.235E-4 8.776E-3
7.453E-2
6.123E-1
2 109
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 290 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0752347 Lewy Body Disease DisGeNET Curated 2.957E-11 8.576E-9 5.359E-8 8.576E-9 5 129
2 C0751783 Lafora Disease DisGeNET Curated 4.340E-10 6.293E-8 3.933E-7 1.259E-7 4 51
3 C0011253 Delusions DisGeNET Curated 6.322E-8 5.522E-6 3.451E-5 1.834E-5 3 31
4 C1112261 Gaze palsy DisGeNET BeFree 7.617E-8 5.522E-6 3.451E-5 2.209E-5 2 2
5 OMIN:127750 DEMENTIA, LEWY BODY; DLB OMIM 2.285E-7 9.465E-6 5.915E-5 6.626E-5 2 3
6 C1851959 Fluctuations in consciousness DisGeNET Curated 2.285E-7 9.465E-6 5.915E-5 6.626E-5 2 3
7 cv:C0752347 Lewy body dementia Clinical Variations 2.285E-7 9.465E-6 5.915E-5 6.626E-5 2 3
8 C0349081 Dementia in Parkinson's disease DisGeNET BeFree 4.569E-7 1.656E-5 1.035E-4 1.325E-4 2 4
9 C0233763 Hallucinations, Visual DisGeNET Curated 3.424E-6 1.103E-4 6.894E-4 9.930E-4 2 10
10 C0276496 Familial Alzheimer Disease (FAD) DisGeNET BeFree 3.918E-6 1.136E-4 7.099E-4 1.136E-3 3 120
11 C0242422 Parkinsonian Disorders DisGeNET Curated 1.686E-5 4.444E-4 2.777E-3 4.888E-3 3 195
12 C0240735 Personality change DisGeNET Curated 2.096E-5 5.066E-4 3.166E-3 6.080E-3 2 24
13 C0426980 Motor symptoms DisGeNET BeFree 5.913E-5 1.319E-3 8.243E-3 1.715E-2 2 40
14 C0011265 Presenile dementia DisGeNET BeFree 7.001E-5 1.450E-3 9.062E-3 2.030E-2 3 314
15 C0233565 Bradykinesia DisGeNET Curated 8.905E-5 1.722E-3 1.076E-2 2.583E-2 2 49
16 C0497327 Dementia DisGeNET Curated 1.355E-4 2.229E-3 1.393E-2 3.929E-2 3 392
17 C0270736 Essential Tremor DisGeNET Curated 1.384E-4 2.229E-3 1.393E-2 4.013E-2 2 61
18 C0018524 Hallucinations DisGeNET Curated 1.384E-4 2.229E-3 1.393E-2 4.013E-2 2 61
19 C0037019 Shy-Drager Syndrome DisGeNET Curated 2.151E-4 2.557E-3 1.598E-2
6.238E-2
2 76
20 C1836151 Frontolimbic dementia DisGeNET Curated 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
21 cv:C1854182 Parkinson disease 4 Clinical Variations 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
22 OMIN:260540 PARKINSON-DEMENTIA SYNDROME OMIM 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
23 OMIN:601104 SUPRANUCLEAR PALSY, PROGRESSIVE, 1; PSNP1 OMIM 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
24 C1868595 PARKINSON DISEASE 1, AUTOSOMAL DOMINANT (disorder) DisGeNET Curated 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
25 OMIN:605543 PARKINSON DISEASE 4, AUTOSOMAL DOMINANT; PARK4 OMIM 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
26 C0751421 Hemispatial Neglect DisGeNET BeFree 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
27 OMIN:168601 PARKINSON DISEASE 1, AUTOSOMAL DOMINANT; PARK1 OMIM 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
28 C0333454 Granulovacuolar degeneration DisGeNET Curated 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
29 C1854182 PARKINSON DISEASE 4, AUTOSOMAL DOMINANT LEWY BODY (disorder) DisGeNET Curated 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
30 cv:C1850076 Parkinson-dementia syndrome Clinical Variations 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
31 C1850077 Supranuclear Palsy, Progressive, 1, Atypical DisGeNET Curated 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
32 C1838313 Pick Complex DisGeNET BeFree 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
33 cv:C0038868 Progressive supranuclear ophthalmoplegia Clinical Variations 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
34 cv:C1868595 Parkinson disease 1 Clinical Variations 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
35 C0270920 Supranuclear paralysis DisGeNET BeFree 3.085E-4 2.557E-3 1.598E-2
8.948E-2
1 1
36 C0236642 Pick Disease of the Brain DisGeNET Curated 3.222E-4 2.595E-3 1.622E-2
9.344E-2
2 93
37 C0751072 Frontotemporal Lobar Degeneration DisGeNET Curated 3.505E-4 2.715E-3 1.696E-2
1.016E-1
2 97
38 C0026837 Muscle Rigidity DisGeNET Curated 3.577E-4 2.715E-3 1.696E-2
1.037E-1
2 98
39 C3160718 PARKINSON DISEASE, LATE-ONSET DisGeNET Curated 3.651E-4 2.715E-3 1.696E-2
1.059E-1
2 99
40 C1262477 Weight decreased DisGeNET Curated 4.028E-4 2.921E-3 1.825E-2
1.168E-1
2 104
41 C0027066 Myoclonus DisGeNET Curated 4.184E-4 2.960E-3 1.849E-2
1.213E-1
2 106
42 C0949664 Tauopathies DisGeNET Curated 5.907E-4 3.376E-3 2.110E-2
1.713E-1
2 126
43 cv:C0236642 Pick's disease Clinical Variations 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
44 C0520789 Progressive subcortical gliosis DisGeNET BeFree 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
45 C0236688 Cocaine delirium DisGeNET BeFree 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
46 OMIN:600274 FRONTOTEMPORAL DEMENTIA; FTD OMIM 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
47 C1850100 PARKINSON DISEASE 15, AUTOSOMAL RECESSIVE (disorder) DisGeNET Curated 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
48 C0003550 Broca Aphasia DisGeNET Curated 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
49 C0520716 Pallidopontonigral degeneration DisGeNET BeFree 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
50 C1142448 Apraxia of eyelid DisGeNET Curated 6.170E-4 3.376E-3 2.110E-2
1.789E-1
1 2
Show 45 more annotations