Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc161_7, positive side

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1: GO: Molecular Function [Display Chart] 7 input genes in category / 88 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0030515 snoRNA binding 4.538E-5 3.994E-3 2.021E-2 3.994E-3 2 28
2 GO:0003963 RNA-3'-phosphate cyclase activity 7.501E-4 1.650E-2
8.351E-2
6.601E-2
 1 2
3 GO:0036009 protein-glutamine N-methyltransferase activity 7.501E-4 1.650E-2
8.351E-2
6.601E-2
 1 2
4 GO:1990259 histone-glutamine methyltransferase activity 7.501E-4 1.650E-2
8.351E-2
6.601E-2
 1 2
5 GO:0034511 U3 snoRNA binding 2.249E-3 3.768E-2
1.907E-1
1.979E-1
 1 6
6 GO:0001094 TFIID-class transcription factor complex binding 2.623E-3 3.768E-2
1.907E-1
2.308E-1
 1 7
7 GO:0001091 RNA polymerase II basal transcription factor binding 2.998E-3 3.768E-2
1.907E-1
2.638E-1
 1 8
8 GO:0016886 ligase activity, forming phosphoric ester bonds 3.746E-3 3.880E-2
1.963E-1
3.296E-1
 1 10
9 GO:0009975 cyclase activity 8.597E-3 3.880E-2
1.963E-1
7.566E-1
 1 23
10 GO:0001099 basal RNA polymerase II transcription machinery binding 1.046E-2 3.880E-2
1.963E-1
9.203E-1
 1 28
11 GO:0001098 basal transcription machinery binding 1.046E-2 3.880E-2
1.963E-1
9.203E-1
 1 28
12 GO:0004521 endoribonuclease activity 2.119E-2 3.880E-2
1.963E-1
1.000E0
 1 57
13 GO:0042054 histone methyltransferase activity 2.193E-2 3.880E-2
1.963E-1
1.000E0
 1 59
14 GO:0051995 Se-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
15 GO:0052665 tRNA (uracil-2'-O-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
16 GO:0043834 trimethylamine methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
17 GO:0070677 rRNA (cytosine-2'-O-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
18 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
19 GO:0043782 cobalt-precorrin-3 C17-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
20 GO:0043791 dimethylamine methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
21 GO:0043776 cobalt-precorrin-6B C5-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
22 GO:0043803 hydroxyneurosporene-O-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
23 GO:0034931 1-hydroxypyrene methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
24 GO:0008650 rRNA (uridine-2'-O-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
25 GO:0018707 1-phenanthrol methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
26 GO:0043833 methylamine-specific methylcobalamin:coenzyme M methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
27 GO:0043851 methanol-specific methylcobalamin:coenzyme M methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
28 GO:0016205 selenocysteine methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
29 GO:0051994 P-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
30 GO:0043777 cobalt-precorrin-7 C15-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
31 GO:0016435 rRNA (guanine) methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
32 GO:0043827 tRNA (adenine-57, 58-N(1)-) methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
33 GO:0008988 rRNA (adenine-N6-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
34 GO:0052735 tRNA (cytosine-3-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
35 GO:0034933 1-hydroxy-6-methoxypyrene methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
36 GO:0034807 4,5-dihydroxybenzo(a)pyrene methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
37 GO:0080012 trihydroxyferuloyl spermidine O-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
38 GO:0043780 cobalt-precorrin-5B C1-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
39 GO:0034541 dimethylarsinite methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
40 GO:0019702 protein-arginine N5-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
41 GO:0052667 phosphomethylethanolamine N-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
42 GO:0052666 tRNA (cytosine-2'-O-)-methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
43 GO:0052624 2-phytyl-1,4-naphthoquinone methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
44 GO:0043770 demethylmenaquinone methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
45 GO:0043852 monomethylamine methyltransferase activity 2.926E-2 3.880E-2
1.963E-1
1.000E0
 1 79
46 GO:0018423 protein C-terminal leucine carboxyl O-methyltransferase activity 2.963E-2 3.880E-2
1.963E-1
1.000E0
 1 80
47 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity 2.963E-2 3.880E-2
1.963E-1
1.000E0
 1 80
48 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity 2.963E-2 3.880E-2
1.963E-1
1.000E0
 1 80
49 GO:0071424 rRNA (cytosine-N4-)-methyltransferase activity 2.963E-2 3.880E-2
1.963E-1
1.000E0
 1 80
50 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity 2.963E-2 3.880E-2
1.963E-1
1.000E0
 1 80
Show 45 more annotations

2: GO: Biological Process [Display Chart] 7 input genes in category / 45 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006364 rRNA processing 9.541E-14 2.591E-12 1.139E-11 4.293E-12 7 260
2 GO:0016072 rRNA metabolic process 1.152E-13 2.591E-12 1.139E-11 5.182E-12 7 267
3 GO:0042254 ribosome biogenesis 4.331E-13 6.497E-12 2.855E-11 1.949E-11 7 322
4 GO:0034470 ncRNA processing 1.968E-12 2.214E-11 9.729E-11 8.855E-11 7 399
5 GO:0022613 ribonucleoprotein complex biogenesis 6.057E-12 5.452E-11 2.396E-10 2.726E-10 7 468
6 GO:0030490 maturation of SSU-rRNA 1.035E-9 7.765E-9 3.413E-8 4.659E-8 4 45
7 GO:0042274 ribosomal small subunit biogenesis 4.693E-9 3.017E-8 1.326E-7 2.112E-7 4 65
8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.117E-7 1.191E-6 5.235E-6 9.528E-6 3 35
9 GO:0034963 box C/D snoRNA processing 7.516E-4 2.819E-3 1.239E-2 3.382E-2 1 2
10 GO:1990258 histone glutamine methylation 7.516E-4 2.819E-3 1.239E-2 3.382E-2 1 2
11 GO:0000494 box C/D snoRNA 3'-end processing 7.516E-4 2.819E-3 1.239E-2 3.382E-2 1 2
12 GO:0033967 box C/D snoRNA metabolic process 7.516E-4 2.819E-3 1.239E-2 3.382E-2 1 2
13 GO:0018364 peptidyl-glutamine methylation 1.503E-3 5.202E-3 2.286E-2
6.763E-2
 1 4
14 GO:0048254 snoRNA localization 1.878E-3 6.037E-3 2.653E-2
8.452E-2
 1 5
15 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 2.253E-3 6.760E-3 2.971E-2
1.014E-1
 1 6
16 GO:0031126 snoRNA 3'-end processing 3.004E-3 7.951E-3 3.494E-2
1.352E-1
 1 8
17 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 3.004E-3 7.951E-3 3.494E-2
1.352E-1
 1 8
18 GO:0043144 snoRNA processing 3.753E-3 9.383E-3 4.124E-2
1.689E-1
 1 10
19 GO:0016074 snoRNA metabolic process 4.503E-3 1.066E-2 4.687E-2
2.026E-1
 1 12
20 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 4.877E-3 1.097E-2 4.823E-2
2.195E-1
 1 13
21 GO:0000478 endonucleolytic cleavage involved in rRNA processing 5.251E-3 1.125E-2 4.946E-2
2.363E-1
 1 14
22 GO:0031167 rRNA methylation 7.495E-3 1.533E-2
6.737E-2
3.373E-1
 1 20
23 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) 7.868E-3 1.539E-2
6.766E-2
3.541E-1
 1 21
24 GO:0043628 ncRNA 3'-end processing 8.615E-3 1.615E-2
7.099E-2
3.877E-1
 1 23
25 GO:0000469 cleavage involved in rRNA processing 9.361E-3 1.685E-2
7.405E-2
4.212E-1
 1 25
26 GO:0000154 rRNA modification 1.048E-2 1.814E-2
7.971E-2
4.716E-1
 1 28
27 GO:0000460 maturation of 5.8S rRNA 1.197E-2 1.995E-2
8.767E-2
5.386E-1
 1 32
28 GO:0001510 RNA methylation 2.160E-2 3.472E-2
1.526E-1
9.721E-1
 1 58
29 GO:0090502 RNA phosphodiester bond hydrolysis, endonucleolytic 2.529E-2 3.924E-2
1.724E-1
1.000E0
 1 68
Show 24 more annotations

3: GO: Cellular Component [Display Chart] 7 input genes in category / 12 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0032040 small-subunit processome 2.781E-13 3.338E-12 1.036E-11 3.338E-12 5 34
2 GO:0030684 preribosome 1.206E-11 4.824E-11 1.497E-10 1.447E-10 5 70
3 GO:0044452 nucleolar part 1.206E-11 4.824E-11 1.497E-10 1.447E-10 5 70
4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome 1.155E-6 3.466E-6 1.076E-5 1.387E-5 2 5
5 GO:0031428 box C/D snoRNP complex 1.733E-6 4.159E-6 1.291E-5 2.079E-5 2 6
6 GO:0005732 small nucleolar ribonucleoprotein complex 2.661E-5 5.322E-5 1.652E-4 3.193E-4 2 22
7 GO:0030686 90S preribosome 4.040E-5 6.926E-5 2.149E-4 4.848E-4 2 27
8 GO:0001651 dense fibrillar component 1.835E-3 2.753E-3 8.542E-3 2.202E-2 1 5
9 GO:0001652 granular component 2.202E-3 2.936E-3 9.110E-3 2.642E-2 1 6
10 GO:0001650 fibrillar center 3.301E-3 3.961E-3 1.229E-2 3.961E-2 1 9
11 GO:0015030 Cajal body 1.967E-2 2.145E-2
6.658E-2
2.360E-1
 1 54
Show 6 more annotations

4: Human Phenotype [Display Chart] 0 input genes in category / 0 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 1 input genes in category / 4 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0011094 embryonic lethality before implantation, complete penetrance 1.468E-2 3.477E-2
7.243E-2
5.872E-2
 1 152
2 MP:0006204 embryonic lethality before implantation 1.738E-2 3.477E-2
7.243E-2
6.953E-2
 1 180
3 MP:0001730 embryonic growth arrest 2.945E-2 3.927E-2
8.182E-2
1.178E-1
 1 305
4 MP:0011101 prenatal lethality, incomplete penetrance 4.220E-2 4.220E-2
8.792E-2
1.688E-1
 1 437

6: Domain [Display Chart] 7 input genes in category / 38 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR019775 WD40 repeat CS InterPro 2.246E-5 5.939E-4 2.511E-3 8.536E-4 3 164
2 PF00400 WD40 Pfam 8.773E-5 5.939E-4 2.511E-3 3.334E-3 3 259
3 SM00320 WD40 SMART 9.709E-5 5.939E-4 2.511E-3 3.690E-3 3 268
4 IPR001680 WD40 repeat InterPro 1.015E-4 5.939E-4 2.511E-3 3.855E-3 3 272
5 PS00678 WD REPEATS 1 PROSITE 1.082E-4 5.939E-4 2.511E-3 4.113E-3 3 278
6 PS50082 WD REPEATS 2 PROSITE 1.094E-4 5.939E-4 2.511E-3 4.157E-3 3 279
7 PS50294 WD REPEATS REGION PROSITE 1.094E-4 5.939E-4 2.511E-3 4.157E-3 3 279
8 IPR017986 WD40 repeat dom InterPro 1.317E-4 6.255E-4 2.644E-3 5.004E-3 3 297
9 2.130.10.10 - Gene3D 1.847E-4 7.099E-4 3.001E-3 7.019E-3 3 333
10 IPR015943 WD40/YVTN repeat-like dom InterPro 1.880E-4 7.099E-4 3.001E-3 7.145E-3 3 335
11 PF01269 Fibrillarin Pfam 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
12 PF08640 U3 assoc 6 Pfam 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
13 PS00566 FIBRILLARIN PROSITE 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
14 PF09384 UTP15 C Pfam 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
15 IPR020813 Fibrillarin CS InterPro 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
16 IPR016443 RNA3' term phos cyc type 2 InterPro 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
17 SM01206 Fibrillarin SMART 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
18 IPR018983 U3 snoRNA-assocProt 15 C InterPro 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
19 IPR013949 Utp6 InterPro 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
20 IPR000692 Fibrillarin InterPro 3.736E-4 7.099E-4 3.001E-3 1.420E-2 1 1
21 IPR020719 RNA3' term phos cycl-like CS InterPro 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
22 PF01137 RTC Pfam 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
23 PS01287 RTC PROSITE 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
24 IPR023797 RNA3' phos cyclase dom InterPro 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
25 IPR000228 RNA3' term phos cyc InterPro 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
26 IPR006709 SSU processome Utp14 InterPro 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
27 IPR013791 RNA3'-term phos cycl insert InterPro 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
28 3.65.10.20 - Gene3D 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
29 PF05189 RTC insert Pfam 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
30 PF04615 Utp14 Pfam 7.471E-4 9.464E-4 4.001E-3 2.839E-2 1 2
31 IPR013792 RNA3'P cycl/enolpyr Trfase a/b InterPro 1.121E-3 1.374E-3 5.807E-3 4.258E-2 1 3
32 SM00386 HAT SMART 3.731E-3 4.296E-3 1.816E-2
1.418E-1
 1 10
33 IPR003107 HAT InterPro 3.731E-3 4.296E-3 1.816E-2
1.418E-1
 1 10
34 IPR020472 G-protein beta WD-40 rep InterPro 3.133E-2 3.502E-2
1.481E-1
1.000E0
 1 85
35 3.40.50.150 - Gene3D 4.399E-2 4.719E-2
1.995E-1
1.000E0
 1 120
36 IPR029063 SAM-dependent MTases InterPro 4.471E-2 4.719E-2
1.995E-1
1.000E0
 1 122
Show 31 more annotations

7: Pathway [Display Chart] 7 input genes in category / 6 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1383087 rRNA modification in the nucleus and cytosol BioSystems: REACTOME 6.024E-17 3.615E-16 8.856E-16 3.615E-16 7 63
2 1383086 Major pathway of rRNA processing in the nucleolus and cytosol BioSystems: REACTOME 1.223E-13 3.668E-13 8.986E-13 7.336E-13 7 181
3 1427846 rRNA processing in the nucleus and cytosol BioSystems: REACTOME 1.930E-13 3.861E-13 9.459E-13 1.158E-12 7 193
4 1383085 rRNA processing BioSystems: REACTOME 2.764E-13 4.147E-13 1.016E-12 1.659E-12 7 203
5 199378 Ribosome biogenesis in eukaryotes BioSystems: KEGG 2.296E-12 2.755E-12 6.749E-12 1.377E-11 6 106
6 M5374 The SARS-coronavirus Life Cycle MSigDB C2 BIOCARTA (v6.0) 5.610E-3 5.610E-3 1.375E-2 3.366E-2 1 10
Show 1 more annotation

8: Pubmed [Display Chart] 7 input genes in category / 209 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 25693804 Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. Pubmed 2.866E-12 3.270E-10 1.937E-9 5.990E-10 6 332
2 12429849 Functional proteomic analysis of human nucleolus. Pubmed 3.129E-12 3.270E-10 1.937E-9 6.540E-10 5 106
3 22916032 NOL11, implicated in the pathogenesis of North American Indian childhood cirrhosis, is required for pre-rRNA transcription and processing. Pubmed 2.879E-7 2.005E-5 1.188E-4 6.016E-5 2 5
4 15635413 Nucleolar proteome dynamics. Pubmed 4.869E-7 2.544E-5 1.507E-4 1.018E-4 4 419
5 15574333 Assembly and maturation of the U3 snoRNP in the nucleoplasm in a large dynamic multiprotein complex. Pubmed 1.036E-6 4.330E-5 2.564E-4 2.165E-4 2 9
6 26336360 Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis. Pubmed 2.312E-6 7.875E-5 4.664E-4 4.831E-4 3 156
7 22113938 A bead-based approach for large-scale identification of in vitro kinase substrates. Pubmed 2.638E-6 7.875E-5 4.664E-4 5.513E-4 3 163
8 11790298 Directed proteomic analysis of the human nucleolus. Pubmed 5.483E-6 1.433E-4 8.483E-4 1.146E-3 3 208
9 27926873 FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3. Pubmed 9.287E-6 2.157E-4 1.277E-3 1.941E-3 3 248
10 23752268 The functional interactome landscape of the human histone deacetylase family. Pubmed 1.437E-5 3.004E-4 1.779E-3 3.004E-3 3 287
11 22922362 Transcription factor Foxp3 and its protein partners form a complex regulatory network. Pubmed 2.780E-5 5.282E-4 3.128E-3 5.810E-3 3 358
12 10790377 Rcl1p, the yeast protein similar to the RNA 3'-phosphate cyclase, associates with U3 snoRNP and is required for 18S rRNA biogenesis. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
13 28218222 Human U Three Protein 14a Expression is Increased in Hepatocellular Carcinoma and Associated with Poor Prognosis. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
14 1731817 Autoantibody to U3 nucleolar ribonucleoprotein (fibrillarin) in patients with systemic sclerosis. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
15 2026646 Evolutionary conservation of the human nucleolar protein fibrillarin and its functional expression in yeast. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
16 17603021 Fibrillarin, a nucleolar protein, is required for normal nuclear morphology and cellular growth in HeLa cells. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
17 8218401 Molecular cloning and sequence analysis of U3 snoRNA-associated mouse fibrillarin. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
18 8735370 Immunocytochemical localisation of the nucleolar protein fibrillarin and RNA polymerase I during mouse early embryogenesis. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
19 11739535 Systemic sclerosis (scleroderma): specific autoantigen genes are selectively overexpressed in scleroderma fibroblasts. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
20 14612397 Fibrillarin is essential for early development and required for accumulation of an intron-encoded small nucleolar RNA in the mouse. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
21 19333934 Anti-U3 RNP autoantibodies in systemic sclerosis. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
22 2414294 Purification and partial characterization of a nucleolar scleroderma antigen (Mr = 34,000; pI, 8.5) rich in NG,NG-dimethylarginine. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
23 10982864 Interaction of the U3-55k protein with U3 snoRNA is mediated by the box B/C motif of U3 and the WD repeats of U3-55k. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
24 30190478 Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
25 26204768 [Analysis of the Localization of Fibrillarin and Sites of Pre-rRNA Synthesis in the Nucleolus-Like Bodies of Mouse GV Oocytes after Mild Treatment with Proteinase K]. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
26 16136320 The perichromosomal layer. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
27 24352239 Glutamine methylation in histone H2A is an RNA-polymerase-I-dedicated modification. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
28 3416880 Purification of RNA 3'-terminal phosphate cyclase from HeLa cells. Covalent modification of the enzyme with different nucleotides. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
29 1846968 cDNA cloning and sequencing of human fibrillarin, a conserved nucleolar protein recognized by autoimmune antisera. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
30 12381732 The hU3-55K protein requires 15.5K binding to the box B/C motif as well as flanking RNA elements for its association with the U3 small nucleolar RNA in Vitro. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
31 9418896 cDNA cloning and characterization of the human U3 small nucleolar ribonucleoprotein complex-associated 55-kilodalton protein. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
32 12373336 U3 snoRNP associates with fibrillarin a component of the scleroderma clumpy nucleolar domain. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
33 12490167 Proteasome-dependent processing of nuclear proteins is correlated with their subnuclear localization. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
34 7626687 Nucleolin and fibrillarin expression in stimulated lymphocytes and differentiating HL-60 cells. A flow cytometric assay. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
35 10518318 Arginine methylation of a glycine and arginine rich peptide derived from sequences of human FMRP and fibrillarin. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
36 27682166 Nucleolar Methyltransferase Fibrillarin: Evolution of Structure and Functions. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
37 1714385 An intact Box C sequence in the U3 snRNA is required for binding of fibrillarin, the protein common to the major family of nucleolar snRNPs. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
38 28672776 Human U3 protein 14a plays an anti-apoptotic role in cancer cells. Pubmed 1.833E-4 1.008E-3 5.970E-3 3.831E-2 1 1
39 19331828 Fibrillarin and Nop56 interact before being co-assembled in box C/D snoRNPs. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
40 21505065 A weak C' box renders U3 snoRNA levels dependent on hU3-55K binding. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
41 21078665 A small ribosomal subunit (SSU) processome component, the human U3 protein 14A (hUTP14A) binds p53 and promotes p53 degradation. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
42 27614293 Disruption of the UBF gene induces aberrant somatic nucleolar bodies and disrupts embryo nucleolar precursor bodies. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
43 12388758 Subcellular recruitment of fibrillarin to nucleoplasmic proteasomes: implications for processing of a nucleolar autoantigen. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
44 11835310 Nerve growth factor-mediated increases in protein methylation occur predominantly at type I arginine methylation sites and involve protein arginine methyltransferase 1. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
45 29545198 Mice Expressing Myc in Neural Precursors Develop Choroid Plexus and Ciliary Body Tumors. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
46 22434888 Mammalian HCA66 protein is required for both ribosome synthesis and centriole duplication. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
47 17380155 Positive regulation of apoptosis by HCA66, a new Apaf-1 interacting protein, and its putative role in the physiopathology of NF1 microdeletion syndrome patients. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
48 17498821 Human 1A6/DRIM, the homolog of yeast Utp20, functions in the 18S rRNA processing. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
49 24029231 p53 acts as a safeguard of translational control by regulating fibrillarin and rRNA methylation in cancer. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
50 15908283 Molecular cloning and expression pattern of the Fkbp25 gene during cerebral cortical neurogenesis. Pubmed 3.665E-4 1.344E-3 7.959E-3
7.660E-2
 1 2
Show 45 more annotations

9: Interaction [Display Chart] 7 input genes in category / 378 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:IFI16 IFI16 interactions 4.749E-10 1.795E-7 1.169E-6 1.795E-7 6 361
2 int:MPHOSPH10 MPHOSPH10 interactions 2.687E-9 5.079E-7 3.308E-6 1.016E-6 4 54
3 int:WDR36 WDR36 interactions 1.087E-8 1.370E-6 8.921E-6 4.109E-6 4 76
4 int:DCAF13 DCAF13 interactions 2.055E-7 1.942E-5 1.265E-4 7.768E-5 3 33
5 int:RBM19 RBM19 interactions 6.498E-7 4.913E-5 3.200E-4 2.456E-4 3 48
6 int:FBL FBL interactions 1.609E-6 1.014E-4 6.603E-4 6.082E-4 4 263
7 int:TBL3 TBL3 interactions 1.961E-6 1.059E-4 6.899E-4 7.414E-4 3 69
8 int:SNORD3A SNORD3A interactions 7.359E-6 3.477E-4 2.265E-3 2.782E-3 2 11
9 int:PUM3 PUM3 interactions 1.388E-5 5.828E-4 3.796E-3 5.245E-3 3 132
10 int:NOP58 NOP58 interactions 1.620E-5 6.125E-4 3.989E-3 6.125E-3 3 139
11 int:HDAC11 HDAC11 interactions 1.877E-5 6.451E-4 4.202E-3 7.096E-3 3 146
12 int:UTP18 UTP18 interactions 5.041E-5 1.588E-3 1.034E-2 1.906E-2 2 28
13 int:NOL11 NOL11 interactions 6.198E-5 1.802E-3 1.174E-2 2.343E-2 2 31
14 int:PHF10 PHF10 interactions 7.925E-5 2.140E-3 1.394E-2 2.996E-2 2 35
15 int:RRP9 RRP9 interactions 9.358E-5 2.358E-3 1.536E-2 3.537E-2 2 38
16 int:UTP15 UTP15 interactions 1.038E-4 2.452E-3 1.597E-2 3.923E-2 2 40
17 int:NOP56 NOP56 interactions 1.363E-4 2.855E-3 1.859E-2
5.153E-2
 3 284
18 int:UTP4 UTP4 interactions 1.376E-4 2.855E-3 1.859E-2
5.200E-2
 2 46
19 int:PWP2 PWP2 interactions 1.437E-4 2.855E-3 1.859E-2
5.430E-2
 2 47
20 int:FOXA1 FOXA1 interactions 1.510E-4 2.855E-3 1.859E-2
5.709E-2
 3 294
21 int:SUZ12 SUZ12 interactions 2.636E-4 4.733E-3 3.083E-2
9.964E-2
 3 355
22 int:PNO1 PNO1 interactions 2.755E-4 4.733E-3 3.083E-2
1.041E-1
 2 65
23 int:FOXP3 FOXP3 interactions 4.203E-4 6.907E-3 4.499E-2
1.589E-1
 3 416
24 int:DDX27 DDX27 interactions 5.279E-4 8.315E-3
5.416E-2
1.996E-1
 2 90
25 int:HNRNPK HNRNPK interactions 7.034E-4 1.063E-2
6.926E-2
2.659E-1
 3 496
26 int:DDX56 DDX56 interactions 7.314E-4 1.063E-2
6.926E-2
2.765E-1
 2 106
27 int:ZNF93 ZNF93 interactions 7.907E-4 1.107E-2
7.210E-2
2.989E-1
 1 2
28 int:NOL6 NOL6 interactions 8.900E-4 1.201E-2
7.826E-2
3.364E-1
 2 117
29 int:BRIX1 BRIX1 interactions 9.514E-4 1.238E-2
8.067E-2
3.596E-1
 2 121
30 int:DDX18 DDX18 interactions 9.829E-4 1.238E-2
8.067E-2
3.715E-1
 2 123
31 int:PES1 PES1 interactions 1.080E-3 1.317E-2
8.580E-2
4.084E-1
 2 129
32 int:BYSL BYSL interactions 1.148E-3 1.356E-2
8.831E-2
4.339E-1
 2 133
33 int:NOLC1 NOLC1 interactions 1.200E-3 1.374E-2
8.950E-2
4.535E-1
 2 136
34 int:GTPBP4 GTPBP4 interactions 1.307E-3 1.411E-2
9.192E-2
4.940E-1
 2 142
35 int:FTSJ3 FTSJ3 interactions 1.307E-3 1.411E-2
9.192E-2
4.940E-1
 2 142
36 int:CCDC85B CCDC85B interactions 1.418E-3 1.489E-2
9.700E-2
5.361E-1
 2 148
37 int:DKC1 DKC1 interactions 1.574E-3 1.603E-2
1.044E-1
5.950E-1
 2 156
38 int:NIFK NIFK interactions 1.634E-3 1.603E-2
1.044E-1
6.178E-1
 2 159
39 int:LIN28A LIN28A interactions 1.696E-3 1.603E-2
1.044E-1
6.410E-1
 2 162
40 int:NOP2 NOP2 interactions 1.696E-3 1.603E-2
1.044E-1
6.410E-1
 2 162
41 int:PDZK1IP1 PDZK1IP1 interactions 1.976E-3 1.798E-2
1.171E-1
7.468E-1
 1 5
42 int:TNFRSF1A TNFRSF1A interactions 1.997E-3 1.798E-2
1.171E-1
7.550E-1
 2 176
43 int:SNU13 SNU13 interactions 2.180E-3 1.917E-2
1.248E-1
8.241E-1
 2 184
44 int:HDGF HDGF interactions 3.154E-3 2.654E-2
1.729E-1
1.000E0
 2 222
45 int:ZNF430 ZNF430 interactions 3.160E-3 2.654E-2
1.729E-1
1.000E0
 1 8
46 int:RHOH RHOH interactions 3.554E-3 2.858E-2
1.862E-1
1.000E0
 1 9
47 int:NAP1L3 NAP1L3 interactions 3.554E-3 2.858E-2
1.862E-1
1.000E0
 1 9
48 int:GXYLT2 GXYLT2 interactions 4.342E-3 3.419E-2
2.227E-1
1.000E0
 1 11
49 int:SRRM2 SRRM2 interactions 4.728E-3 3.510E-2
2.286E-1
1.000E0
 2 273
50 int:HMGN5 HMGN5 interactions 4.736E-3 3.510E-2
2.286E-1
1.000E0
 1 12
Show 45 more annotations

10: Cytoband [Display Chart] 7 input genes in category / 7 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 9p24.1-p23 9p24.1-p23 4.039E-4 2.827E-3 7.330E-3 2.827E-3 1 2
2 Xq26.1 Xq26.1 3.227E-3 9.409E-3 2.440E-2 2.259E-2 1 16
3 3p21.2 3p21.2 4.032E-3 9.409E-3 2.440E-2 2.823E-2 1 20
4 17q21.33 17q21.33 8.452E-3 1.313E-2 3.405E-2
5.916E-2
 1 42
5 19q13.1 19q13.1 1.106E-2 1.313E-2 3.405E-2
7.739E-2
 1 55
6 5q13.2 5q13.2 1.126E-2 1.313E-2 3.405E-2
7.879E-2
 1 56
7 17q11.2 17q11.2 2.280E-2 2.280E-2
5.911E-2
1.596E-1
 1 114
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 3 input genes in category / 16 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$NMYC 01 V$NMYC 01 1.478E-3 1.204E-2 4.071E-2 2.365E-2 2 219
2 V$MYCMAX 02 V$MYCMAX 02 1.505E-3 1.204E-2 4.071E-2 2.409E-2 2 221

12: Gene Family [Display Chart] 4 input genes in category / 2 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1225 WD repeat domain containing|UTPB complex genenames.org 5.436E-7 1.087E-6 1.631E-6 1.087E-6 2 6
2 362 Ring finger proteins|WD repeat domain containing genenames.org 1.168E-5 1.168E-5 1.753E-5 2.337E-5 3 262

13: Coexpression [Display Chart] 7 input genes in category / 624 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M8863 Genes up-regulated in lymphoid primed multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.821E-7 3.865E-5 2.711E-4 1.136E-4 4 199
2 M9736 Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus Ly6c int CXCR5+ [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.858E-7 3.865E-5 2.711E-4 1.160E-4 4 200
3 M9734 Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 1.858E-7 3.865E-5 2.711E-4 1.160E-4 4 200
4 16273092-TableS1a Human InVitro Bild06 206genes GeneSigDB 1.177E-5 1.231E-3 8.638E-3 7.343E-3 3 163
5 M2711 Genes up-regulated in primary epithelial breast cancer cell culture over-expressing MYC [Gene ID=4609] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.664E-5 1.231E-3 8.638E-3 1.039E-2 3 183
6 M4302 Genes down-regulated in comparison of effector CD8 IL2RA [GeneID=3559] low T cells versus effector CD8 IL2RA [GeneID=3559] high cells. MSigDB C7: Immunologic Signatures (v6.0) 2.107E-5 1.231E-3 8.638E-3 1.315E-2 3 198
7 M4393 Genes up-regulated in comparison of dendritic cells (DC) treated with CpG DNA (TLR9 agonist) DNA versus the untreated cells. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 1.231E-3 8.638E-3 1.355E-2 3 200
8 M6926 Genes down-regulated in B lymphocytes: control versus anti IgM and cell anti IgM and CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 1.231E-3 8.638E-3 1.355E-2 3 200
9 M9738 Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naïve versus memory follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 1.231E-3 8.638E-3 1.355E-2 3 200
10 M8628 Genes down-regulated in bone marrow-derived dendritic cells: low dose of 1,3-beta-D-oligoglucan [PubChem=11375554] versus CSF2 [GeneID=1437] and low dose of 1,3-beta-D-oligoglucan [PubChem=11375554]. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 1.231E-3 8.638E-3 1.355E-2 3 200
11 M6935 Genes down-regulated in B lymphocytes: anti IgM versus anti IgM and CpG oligodeoxynucleotide 1826. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 1.231E-3 8.638E-3 1.355E-2 3 200
12 M2069 Genes selected in supervised analyses to discriminate cells expressing c-Myc [GeneID=4609] from control cells expressing GFP. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.371E-5 1.233E-3 8.649E-3 1.480E-2 3 206
13 M2138 Cluster 6: genes down-regulated in B493-6 cells (B lymphocytes) by MYC [GeneID=4609] in combination with serum but not affected by serum alone; they are also up-regulated by MYC alone. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.427E-5 4.045E-3 2.837E-2
5.258E-2
 2 47
14 M13936 Genes down-regulated in BJAB cells (B-lymphoma) after glutamine [PubChem=738] deprivation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.026E-4 4.575E-3 3.209E-2
6.405E-2
 3 337
15 M5928 A subgroup of genes regulated by MYC - version 2 (v2). MSigDB H: Hallmark Gene Sets (v6.0) 1.287E-4 5.352E-3 3.754E-2
8.028E-2
 2 58
16 M13893 Genes down-regulated in Daudi cells (B lymphocytes) stably expressing CD5 [GeneID=921] off a plasmid vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.125E-4 8.288E-3
5.813E-2
1.326E-1
 3 431
17 M9114 Genes up-regulated in CD4 T conv: control versus over-expression of SATB1 and FOXP3 [GeneID=6304;50943]. MSigDB C7: Immunologic Signatures (v6.0) 9.999E-4 1.427E-2
1.001E-1
6.239E-1
 2 162
18 M2990 Genes down-regulated in B lymphocytes with ZFX [GeneID=7543] knockout: control versus stimulated by anti-IgM for 2h. MSigDB C7: Immunologic Signatures (v6.0) 1.075E-3 1.427E-2
1.001E-1
6.706E-1
 2 168
19 M2980 Genes down-regulated in B lymphocytes: control versus stimulated by anti-IgM for 12h. MSigDB C7: Immunologic Signatures (v6.0) 1.100E-3 1.427E-2
1.001E-1
6.865E-1
 2 170
20 17533364-TableS2 Human Brain Lastowska07 256genes GeneSigDB 1.126E-3 1.427E-2
1.001E-1
7.026E-1
 2 172
21 M394 Genes down-regulated in neutrophils from MIR223 [GeneID=407008] bone marrow versus the wildtype cells. MSigDB C7: Immunologic Signatures (v6.0) 1.192E-3 1.427E-2
1.001E-1
7.436E-1
 2 177
22 M4203 Genes with copy number gains in primary neuroblastoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.232E-3 1.427E-2
1.001E-1
7.687E-1
 2 180
23 M10828 Human orthologs of genes up-regulated in the crb ('crash and burn') zebrafish mutant that represents a loss-of-function mutation in BMYB [GeneID=4605]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.473E-3 1.427E-2
1.001E-1
9.190E-1
 2 197
24 M8442 Genes down-regulated in CD8 T cells: effector memory versus naïve. MSigDB C7: Immunologic Signatures (v6.0) 1.488E-3 1.427E-2
1.001E-1
9.282E-1
 2 198
25 M5411 Genes down-regulated in comparison of eosinophils versus B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
26 M8687 Genes up-regulated in monocytes (6h): muramyl dipeptide [PubChem=11620162] versus muramyl dipeptide [PubChem=11620162] and M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
27 M7264 Genes up-regulated in bone marrow-derived macrophages: control versus Listeria infected. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
28 M8444 Genes down-regulated in lung innate lymphoid cells versus spleen CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
29 M7558 Genes up-regulated in CD11b+ cells from spleen of BALB/c mice: healthy versus bearing C26GM colon carcinoma. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
30 M8960 Genes down-regulated in lymph node from aged PPARG [GeneID=5468] knockout mice: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
31 M9322 Genes up-regulated in marginal zone B cells versus day 7 plasma cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 1.427E-2
1.001E-1
9.375E-1
 2 199
32 M7819 Genes down-regulated in amplified multipotent progenitors versus common dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
33 M5525 Genes down-regulated in comparison of neutrophils versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
34 M8650 Genes up-regulated in bone marrow-derived macrophages: control versus stimulated with LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
35 M5191 Genes down-regulated in comparison of dendritic cells (DC) exposed to M. tuberculosis versus macrophages exposed to L. major. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
36 M7197 Genes down-regulated in B lymphocytes: naïve versus transitional CR2 [GeneID=1380] low. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
37 M7900 Genes down-regulated in monocytes (12h) versus macrophages (12h) treated with IL4 [GeneID=3565] and rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
38 M3839 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
39 M7492 Genes down-regulated in NCAM+ [GeneID=4684] NK cells: SELL bright [GeneID=6402] versus SELL dim [GeneID=6402]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
40 M6553 Genes up-regulated in monocyte-derived dendritic cells: untreated versus rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
41 M4542 Genes down-regulated in comparison of granulocytic myeloid derived suppressor cells (MDSC) versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
42 M5926 A subgroup of genes regulated by MYC - version 1 (v1). MSigDB H: Hallmark Gene Sets (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
43 M6632 Genes down-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min stimulation by: LPS versus IL6 [GeneID=3469] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
44 M9845 Genes up-regulated in CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4high versus CD40L and IL-2 IL-4 IL-5 stimulated at day 3 B cell IRF4intermediate. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
45 M8462 Genes up-regulated in activated CD4 [GeneID=920] T cells: wildtype versus over-expressing MIR17 [GeneID=406952]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
46 M10031 Genes up-regulated in NK cells versus B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
47 M4115 Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at all time points versus those stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h only. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
48 M8688 Genes down-regulated in monocytes (6h): muramyl dipeptide [PubChem=11620162] versus muramyl dipeptide [PubChem=11620162] and M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
49 M8966 Genes down-regulated in T conv from visceral adipose tissue in aged mice: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
50 M5837 Genes down-regulated in comparison of effector CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 1.427E-2
1.001E-1
9.469E-1
 2 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 7 input genes in category / 222 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 gudmap dev gonad e11.5 F PrimGermCell Oct k3 1000 dev gonad e11.5 F PrimGermCell Oct k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 6.647E-6 1.476E-3 8.828E-3 1.476E-3 4 463
2 gudmap dev gonad e11.5 M PrimGermCell Oct k4 1000 dev gonad e11.5 M PrimGermCell Oct k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 9.979E-5 8.785E-3
5.255E-2
 2.215E-2 3 315
3 gudmap dev gonad e12.5 M GermCellTestis Oct k1 1000 dev gonad e12.5 M GermCellTestis Oct k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 1.187E-4 8.785E-3
5.255E-2
 2.635E-2 3 334
4 gudmap dev gonad e11.5 F PrimGermCell Oct 500 dev gonad e11.5 F PrimGermCell Oct top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.821E-4 1.011E-2
6.047E-2
 4.044E-2 3 386
5 gudmap dev gonad e11.5 F PrimGermCell Oct k1 500 dev gonad e11.5 F PrimGermCell Oct k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.385E-4 1.947E-2
1.165E-1
9.734E-2
 2 101
6 Facebase ST1 e9.5 OlfacPlacod 500 3 e9.5 OlfacPlacod top-relative-expression-ranked 500 3 FaceBase_ST1 1.163E-3 4.160E-2
2.488E-1
2.582E-1
 2 165
7 Podocyte (PD)/Podocyte (PD) b Podocyte (PD)/Podocyte (PD) b 1.586E-3 4.160E-2
2.488E-1
3.521E-1
 2 193
8 Facebase RNAseq e9.5 Mandibular Arch 500 K1 FacebaseRNAseq e9.5 Mandibular Arch top-relative-expression-ranked 500 k-means-cluster#1 FaceBase_RNAseq 1.619E-3 4.160E-2
2.488E-1
3.594E-1
 2 195
9 Facebase ST1 e8.5 NeuroEpith nonFloorPlate 250 e8.5 NeuroEpith nonFloorPlate top-relative-expression-ranked 250 FaceBase_ST1 1.839E-3 4.160E-2
2.488E-1
4.082E-1
 2 208
10 Facebase ST1 e8.5 NeuroEpith HindBrain 250 e8.5 NeuroEpith HindBrain top-relative-expression-ranked 250 FaceBase_ST1 1.874E-3 4.160E-2
2.488E-1
4.160E-1
 2 210
11 Facebase ST1 e9.5 FaceMesenchy 500 1 e9.5 FaceMesenchy top-relative-expression-ranked 500 1 FaceBase_ST1 2.109E-3 4.257E-2
2.547E-1
4.683E-1
 2 223
12 Sample Type by Project: Shred 1/TCGA-Breast/Breast Carcinoma/Metaplastic Carcinoma/5/4 Sample Type by Project: Shred 1/TCGA-Breast/Breast Carcinoma/Metaplastic Carcinoma/5/4 TCGA-Breast 2.563E-3 4.377E-2
2.618E-1
5.690E-1
 1 8
13 Facebase ST1 e10.5 Emin MedialNasal 500 1 e10.5 Emin MedialNasal top-relative-expression-ranked 500 1 FaceBase_ST1 2.563E-3 4.377E-2
2.618E-1
5.690E-1
 1 8
Show 8 more annotations

15: Computational [Display Chart] 4 input genes in category / 55 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 7 input genes in category / 116 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-4664-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.750E-4 3.009E-2
1.605E-1
8.990E-2
 1 8
2 hsa-miR-8086:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.903E-3 3.009E-2
1.605E-1
3.368E-1
 1 30
3 hsa-miR-6850-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 3.009E-2
1.605E-1
3.929E-1
 1 35
4 hsa-miR-4474-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.449E-3 3.009E-2
1.605E-1
5.161E-1
 1 46
5 hsa-miR-208b-3p:Functional MTI Functional MTI miRTarbase 4.739E-3 3.009E-2
1.605E-1
5.497E-1
 1 49
6 hsa-miR-208a-3p:Functional MTI Functional MTI miRTarbase 5.221E-3 3.009E-2
1.605E-1
6.056E-1
 1 54
7 hsa-miR-6772-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.317E-3 3.009E-2
1.605E-1
6.168E-1
 1 55
8 hsa-miR-1287-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.896E-3 3.009E-2
1.605E-1
6.839E-1
 1 61
9 AGGAGTG,MIR-483:MSigDB AGGAGTG,MIR-483:MSigDB MSigDB 6.089E-3 3.009E-2
1.605E-1
7.063E-1
 1 63
10 hsa-miR-1251-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.185E-3 3.009E-2
1.605E-1
7.175E-1
 1 64
11 hsa-miR-4690-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.185E-3 3.009E-2
1.605E-1
7.175E-1
 1 64
12 hsa-miR-499a-5p:Functional MTI Functional MTI miRTarbase 6.185E-3 3.009E-2
1.605E-1
7.175E-1
 1 64
13 hsa-miR-4804-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.185E-3 3.009E-2
1.605E-1
7.175E-1
 1 64
14 hsa-miR-1180-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.474E-3 3.009E-2
1.605E-1
7.510E-1
 1 67
15 hsa-miR-6744-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.571E-3 3.009E-2
1.605E-1
7.622E-1
 1 68
16 hsa-miR-4503:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.860E-3 3.009E-2
1.605E-1
7.957E-1
 1 71
17 hsa-miR-892b:Functional MTI Functional MTI miRTarbase 6.860E-3 3.009E-2
1.605E-1
7.957E-1
 1 71
18 hsa-miR-6812-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.149E-3 3.009E-2
1.605E-1
8.293E-1
 1 74
19 hsa-miR-502-5p:Functional MTI Functional MTI miRTarbase 7.149E-3 3.009E-2
1.605E-1
8.293E-1
 1 74
20 hsa-miR-4720-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.245E-3 3.009E-2
1.605E-1
8.404E-1
 1 75
21 hsa-miR-323a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.245E-3 3.009E-2
1.605E-1
8.404E-1
 1 75
22 hsa-miR-4448:Functional MTI Functional MTI miRTarbase 7.534E-3 3.009E-2
1.605E-1
8.739E-1
 1 78
23 hsa-miR-4268:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.630E-3 3.009E-2
1.605E-1
8.851E-1
 1 79
24 hsa-miR-5195-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.015E-3 3.009E-2
1.605E-1
9.298E-1
 1 83
25 hsa-miR-7153-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.015E-3 3.009E-2
1.605E-1
9.298E-1
 1 83
26 hsa-miR-1207-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.111E-3 3.009E-2
1.605E-1
9.409E-1
 1 84
27 GAGACTG,MIR-452:MSigDB GAGACTG,MIR-452:MSigDB MSigDB 8.496E-3 3.009E-2
1.605E-1
9.856E-1
 1 88
28 hsa-miR-6822-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.592E-3 3.009E-2
1.605E-1
9.967E-1
 1 89
29 hsa-miR-374c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.169E-3 3.009E-2
1.605E-1
1.000E0
 1 95
30 hsa-miR-374b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.362E-3 3.009E-2
1.605E-1
1.000E0
 1 97
31 hsa-miR-624-3p:Functional MTI Functional MTI miRTarbase 9.746E-3 3.009E-2
1.605E-1
1.000E0
 1 101
32 hsa-miR-655-3p:Functional MTI Functional MTI miRTarbase 9.746E-3 3.009E-2
1.605E-1
1.000E0
 1 101
33 hsa-miR-3617-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.746E-3 3.009E-2
1.605E-1
1.000E0
 1 101
34 hsa-miR-1255a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.842E-3 3.009E-2
1.605E-1
1.000E0
 1 102
35 hsa-miR-1255b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.842E-3 3.009E-2
1.605E-1
1.000E0
 1 102
36 hsa-miR-641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.938E-3 3.009E-2
1.605E-1
1.000E0
 1 103
37 hsa-miR-6792-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.938E-3 3.009E-2
1.605E-1
1.000E0
 1 103
38 hsa-miR-132*:mirSVR highEffct hsa-miR-132*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.023E-2 3.009E-2
1.605E-1
1.000E0
 1 106
39 hsa-miR-6510-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.109E-2 3.009E-2
1.605E-1
1.000E0
 1 115
40 hsa-miR-300:Functional MTI Functional MTI miRTarbase 1.138E-2 3.009E-2
1.605E-1
1.000E0
 1 118
41 hsa-miR-146b-5p:Functional MTI Functional MTI miRTarbase 1.167E-2 3.009E-2
1.605E-1
1.000E0
 1 121
42 hsa-miR-3157-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.167E-2 3.009E-2
1.605E-1
1.000E0
 1 121
43 hsa-miR-944:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.176E-2 3.009E-2
1.605E-1
1.000E0
 1 122
44 hsa-miR-3116:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.176E-2 3.009E-2
1.605E-1
1.000E0
 1 122
45 hsa-miR-302a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.224E-2 3.009E-2
1.605E-1
1.000E0
 1 127
46 hsa-miR-193a-3p:Non-Functional MTI Non-Functional MTI miRTarbase 1.234E-2 3.009E-2
1.605E-1
1.000E0
 1 128
47 hsa-miR-1254:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.272E-2 3.009E-2
1.605E-1
1.000E0
 1 132
48 hsa-miR-505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.291E-2 3.009E-2
1.605E-1
1.000E0
 1 134
49 hsa-miR-381-3p:Functional MTI Functional MTI miRTarbase 1.310E-2 3.009E-2
1.605E-1
1.000E0
 1 136
50 hsa-miR-6165:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.320E-2 3.009E-2
1.605E-1
1.000E0
 1 137
Show 45 more annotations

17: Drug [Display Chart] 7 input genes in category / 1051 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID006914648 U1-6 Stitch 2.487E-7 1.804E-4 1.359E-3 2.614E-4 3 45
2 CID011840989 U1 3 Stitch 3.433E-7 1.804E-4 1.359E-3 3.608E-4 3 50
3 CID011840990 DB08668 Stitch 7.636E-7 2.010E-4 1.515E-3 8.026E-4 3 65
4 CID011840991 U-17 Stitch 7.999E-7 2.010E-4 1.515E-3 8.407E-4 3 66
5 CID000002493 AC1L1DSW Stitch 9.563E-7 2.010E-4 1.515E-3 1.005E-3 3 70
6 CID000015047 pseudouridine Stitch 2.117E-6 3.707E-4 2.794E-3 2.224E-3 3 91
7 CID000000152 NSC333308 Stitch 4.401E-6 6.608E-4 4.979E-3 4.626E-3 3 116
8 CID000132841 archaeosine Stitch 1.526E-5 2.004E-3 1.510E-2 1.603E-2 2 20
9 CID000002029 AC1L1CRO Stitch 6.245E-5 7.293E-3
5.495E-2
6.563E-2
 2 40
10 CID000001177 arabinosyluracil Stitch 1.234E-4 1.297E-2
9.770E-2
1.297E-1
 3 354
11 CID000432735 platinum blue Stitch 3.065E-4 2.684E-2
2.023E-1
3.221E-1
 1 1
12 ctd:C532828 potassium hexachloropalladate(IV) CTD 3.065E-4 2.684E-2
2.023E-1
3.221E-1
 1 1
13 CID000135899 PAFP Stitch 6.129E-4 4.127E-2
3.110E-1
6.441E-1
 1 2
14 CID000140012 diarsine Stitch 6.129E-4 4.127E-2
3.110E-1
6.441E-1
 1 2
15 CID000025223 voranil Stitch 9.192E-4 4.127E-2
3.110E-1
9.660E-1
 1 3
16 CID000062697 poly(styrene-co-butadiene Stitch 9.192E-4 4.127E-2
3.110E-1
9.660E-1
 1 3
17 2938 DN Alprostadil [745-65-3]; Down 200; 11.2uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.195E-3 4.127E-2
3.110E-1
1.000E0
 2 175
18 2977 DN (-)-Quinpirole hydrochloride [85760-74-3]; Down 200; 15.6uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.236E-3 4.127E-2
3.110E-1
1.000E0
 2 178
19 2007 DN Bromocryptine mesylate [22260-51-1]; Down 200; 5.4uM; HL60; HG-U133A Broad Institute CMAP Down 1.278E-3 4.127E-2
3.110E-1
1.000E0
 2 181
20 3141 DN Dimaprit dihydrochloride [23256-33-9]; Down 200; 17uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.292E-3 4.127E-2
3.110E-1
1.000E0
 2 182
21 1339 DN Digitoxigenin [143-62-4]; Down 200; 10.6uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.348E-3 4.127E-2
3.110E-1
1.000E0
 2 186
22 6955 DN ICI 182,780; Down 200; 0.01uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.363E-3 4.127E-2
3.110E-1
1.000E0
 2 187
23 6177 DN 17-AAG; Down 200; 1uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.406E-3 4.127E-2
3.110E-1
1.000E0
 2 190
24 2678 DN 17-AAG; Down 200; 1uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.421E-3 4.127E-2
3.110E-1
1.000E0
 2 191
25 6184 DN 17-AAG; Down 200; 1uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.421E-3 4.127E-2
3.110E-1
1.000E0
 2 191
26 6185 DN 17-AAG; Down 200; 1uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.436E-3 4.127E-2
3.110E-1
1.000E0
 2 192
27 4460 DN LY 294002; Down 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.451E-3 4.127E-2
3.110E-1
1.000E0
 2 193
28 1369 DN Disulfiram [97-77-8]; Down 200; 13.4uM; HL60; HG-U133A Broad Institute CMAP Down 1.465E-3 4.127E-2
3.110E-1
1.000E0
 2 194
29 2410 DN Perhexiline maleate [6724-53-4]; Down 200; 10.2uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.480E-3 4.127E-2
3.110E-1
1.000E0
 2 195
30 4003 UP Tolazamide [1156-19-0]; Up 200; 12.8uM; PC3; HT HG-U133A Broad Institute CMAP Up 1.480E-3 4.127E-2
3.110E-1
1.000E0
 2 195
31 6457 DN Thonzonium bromide [553-08-2]; Down 200; 6.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.480E-3 4.127E-2
3.110E-1
1.000E0
 2 195
32 6172 DN 17-DMAG; Down 200; 0.1uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.480E-3 4.127E-2
3.110E-1
1.000E0
 2 195
33 2208 DN Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.480E-3 4.127E-2
3.110E-1
1.000E0
 2 195
34 5667 DN Metyrapone [54-36-4]; Down 200; 17.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.495E-3 4.127E-2
3.110E-1
1.000E0
 2 196
35 4445 DN Rapamycin; Down 200; 0.1uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.495E-3 4.127E-2
3.110E-1
1.000E0
 2 196
36 3111 DN Iodipamide [606-17-7]; Down 200; 3.6uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.511E-3 4.127E-2
3.110E-1
1.000E0
 2 197
37 1589 DN Dobutamine hydrochloride [49745-95-1]; Down 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Down 1.511E-3 4.127E-2
3.110E-1
1.000E0
 2 197
38 CID006365488 polycarbon monofluoride Stitch 1.532E-3 4.127E-2
3.110E-1
1.000E0
 1 5
39 CID000114901 fenoterol/ipratropium Stitch 1.532E-3 4.127E-2
3.110E-1
1.000E0
 1 5
40 CID000001652 3-deazacytidine Stitch 1.650E-3 4.335E-2
3.267E-1
1.000E0
 2 206
41 CID000009633 HFC-125 Stitch 1.838E-3 4.491E-2
3.384E-1
1.000E0
 1 6
42 CID000015426 dioctyl sulfosuccinate Stitch 1.838E-3 4.491E-2
3.384E-1
1.000E0
 1 6
43 CID000007303 ethylene carbonate Stitch 1.838E-3 4.491E-2
3.384E-1
1.000E0
 1 6
44 CID000000854 D-ribofuranose Stitch 2.016E-3 4.815E-2
3.628E-1
1.000E0
 2 228
45 CID000001296 AC1L1B5W Stitch 2.144E-3 4.898E-2
3.690E-1
1.000E0
 1 7
46 CID000159416 calcium aluminate Stitch 2.144E-3 4.898E-2
3.690E-1
1.000E0
 1 7
Show 41 more annotations

18: Disease [Display Chart] 5 input genes in category / 20 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1258039 Henipavirus Infections DisGeNET BeFree 6.170E-4 8.225E-3 2.959E-2 1.234E-2 1 2
2 C3150928 NF1 Microdeletion Syndrome DisGeNET Curated 9.254E-4 8.225E-3 2.959E-2 1.851E-2 1 3
3 C2364016 Systemic sclerosis [scleroderma] DisGeNET BeFree 1.234E-3 8.225E-3 2.959E-2 2.467E-2 1 4