|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
M5898
|
Genes involved in DNA repair.
|
MSigDB H: Hallmark Gene Sets (v6.0)
|
8.631E-19
|
7.103E-16
|
5.179E-15
|
7.103E-16
|
9
|
150
|
2
|
M8614
|
Genes up-regulated in bone marrow-derived dendritic cells: unstimulated versus high dose of 1,3-beta-D-oligoglucan [PubChem=11375554].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.683E-5
|
1.026E-2
|
7.482E-2
|
7.969E-2
|
3
|
198
|
3
|
M3653
|
Genes down-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after treatment with trichostatin A (TSA) [PubChem=5562].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.828E-5
|
1.026E-2
|
7.482E-2
|
8.089E-2
|
3
|
199
|
4
|
M7651
|
Genes down-regulated in CD4 [GeneID=920] T cells under specific pathogen free conditions: healthy versus arthritis (KRN model).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.828E-5
|
1.026E-2
|
7.482E-2
|
8.089E-2
|
3
|
199
|
5
|
M5162
|
Genes up-regulated in comparison of macrophages versus macrophages exposed to T. gondii.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.976E-5
|
1.026E-2
|
7.482E-2
|
8.210E-2
|
3
|
200
|
6
|
M9477
|
Genes down-regulated in CD8 T effector cells at day 6 of chronic infection: LCMV-Armstrong versus LCMV-Clone 13.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.976E-5
|
1.026E-2
|
7.482E-2
|
8.210E-2
|
3
|
200
|
7
|
M7650
|
Genes up-regulated in CD4 [GeneID=920] T cells under specific pathogen free conditions: healthy versus arthritis (KRN model).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.976E-5
|
1.026E-2
|
7.482E-2
|
8.210E-2
|
3
|
200
|
8
|
M3623
|
Genes up-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with antigen-B7-1.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.976E-5
|
1.026E-2
|
7.482E-2
|
8.210E-2
|
3
|
200
|
9
|
16597596-TableS1-4
|
Human Leukemia Wilson06 50genes SigDifferentialClusterD1
|
GeneSigDB
|
1.668E-4
|
1.274E-2
|
9.286E-2
|
1.373E-1
|
2
|
41
|
10
|
M18854
|
Genes down-regulated in BJUB cells (B-lymphoma) in response to rapamycin (sirolimus) [PubChem=6610346] treatment.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.817E-4
|
1.274E-2
|
9.286E-2
|
1.496E-1
|
3
|
245
|
11
|
16597596-TableS2-4
|
Human Leukemia Wilson06 50genes DifferentialClusterD
|
GeneSigDB
|
2.012E-4
|
1.274E-2
|
9.286E-2
|
1.656E-1
|
2
|
45
|
12
|
M2536
|
Proteins interacting with AIRE [GeneID=326], based on massspectroscopy analysis of co-immunoprecipitates in 293T cells (embryonic kidney).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.012E-4
|
1.274E-2
|
9.286E-2
|
1.656E-1
|
2
|
45
|
13
|
M19667
|
Genes down-regulated in HPL1D cells (lung epithelium) upon exposure to nickel acetate [PubChem=9756].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.012E-4
|
1.274E-2
|
9.286E-2
|
1.656E-1
|
2
|
45
|
14
|
M1415
|
Genes whose expression in bone marrow samples correlated directly with increased levels of serum IL5 [GeneID=3567].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.587E-4
|
1.521E-2
|
1.109E-1
|
2.129E-1
|
2
|
51
|
15
|
12925741-Figure3
|
Human Lymphoma Jenner03 75genes
|
GeneSigDB
|
3.583E-4
|
1.852E-2
|
1.350E-1
|
2.949E-1
|
2
|
60
|
16
|
15492233-TableS1
|
Human Sarcoma Lee04 335genes
|
GeneSigDB
|
3.803E-4
|
1.852E-2
|
1.350E-1
|
3.130E-1
|
3
|
315
|
17
|
M3274
|
Top up-regulated marker genes for medulloblastoma classification: desmoplastic vs classic morphology.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.826E-4
|
1.852E-2
|
1.350E-1
|
3.149E-1
|
2
|
62
|
18
|
M1033
|
Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 10.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
4.738E-4
|
2.052E-2
|
1.496E-1
|
3.899E-1
|
2
|
69
|
19
|
M1507
|
Up-regulated in hepatocytes upon expression of NOS2 [GeneID=4843].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
4.738E-4
|
2.052E-2
|
1.496E-1
|
3.899E-1
|
2
|
69
|
20
|
19336569-SuppTable3
|
Human Breast Zhang09 81genes
|
GeneSigDB
|
5.595E-4
|
2.303E-2
|
1.679E-1
|
4.605E-1
|
2
|
75
|
21
|
M17434
|
Genes up-regulated by forced expression of APC [GeneID=324] in the APC-deficient SW480 cell line (colon cancer).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
5.897E-4
|
2.311E-2
|
1.685E-1
|
4.853E-1
|
2
|
77
|
22
|
M459
|
Cluster 0: genes changed in primary keratinocytes by UVB irradiation.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.134E-3
|
3.074E-2
|
2.241E-1
|
9.333E-1
|
2
|
107
|
23
|
M18086
|
'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757;6623] response of epithelial cell cultures from patients at high risk of breast cancer.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.376E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
118
|
24
|
M17261
|
Downregulated in the vastus lateralis muscle of aged vs young adult rhesus monkeys
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.494E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
123
|
25
|
M10633
|
Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.011E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
143
|
26
|
M411
|
Genes down-regulated in T reg: wildtype versus DICER1 [GeneID=23405] knockout.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.239E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
151
|
27
|
M7115
|
Genes down-regulated in CD4 [GeneID=920] T cells: control versus treated with halofuginone [PubChem=400772] for 3h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.448E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
158
|
28
|
15471956-Table2
|
Human Leukemia Sasaki05 192genes
|
GeneSigDB
|
2.794E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
169
|
29
|
M15171
|
Genes up-regulated in adult T-cell leukemia (ATL) cells compared to T lymphocytes from healthy controls.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.025E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
176
|
30
|
M367
|
Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.335E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
185
|
31
|
M5648
|
Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. pneumoniae infection.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.478E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
189
|
32
|
M3472
|
Genes down-regulated in comparison of CD4 [GeneID=920] thymocytes versus naive CD4 [GeneID=920] T cells from cord blood.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.772E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
197
|
33
|
M4516
|
Genes down-regulated in comparison of NK cells stimulated with IL2 [GeneID=3558] at 16 h versus NK cells stimulated with IL15 [GeneID=3600] at 16 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.809E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
198
|
34
|
M6901
|
Genes down-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 20 min treatment by: LPS versus LPS and IL10 [GeneID=3586].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.809E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
198
|
35
|
M9721
|
Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naïve versus Ly6c low CXCR5- effector during acute infection of LCMV.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.809E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
198
|
36
|
M5877
|
Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus monocytes treated with control IgG.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
37
|
M4283
|
Genes up-regulated in comparison of control conventional dendritic cells (cDC) at 0 h versus cDCs infected with Newcastle disease virus (NDV) at 18 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
38
|
M3919
|
Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 6 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
39
|
M3246
|
Genes down-regulated in comparison of naive B cells versus memory B cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
40
|
M9959
|
Genes down-regulated during primary acute viral infection: NK cells versus B lymphocytes.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
41
|
M7254
|
Genes up-regulated in thymus subcapsular cortical region versus the whole medulla.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
42
|
M8974
|
Genes down-regulated in CD4 [GeneID=920] T cells treated with pioglitazone [PubChem=4829] and over-expressing: FOXP3 [GeneID=50943] and PPARg1 isoform of PPARG [GeneID=5468] versus FOXP3 [GeneID=50943].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.847E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
199
|
43
|
M8507
|
Genes down-regulated in CD8 T cells: control versus over-expressing ID3 [GeneID=3399].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
44
|
M5281
|
Genes down-regulated in comparison of eosinophils treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
45
|
M4398
|
Genes down-regulated in comparison of dendritic cells (DC) treated with CpG DNA (TLR9 agonist) DNA versus the untreated cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
46
|
M5117
|
Genes up-regulated in comparison of CD8 dendritic cells (DC) versus CD4- [GeneID=920] CD8- DCs.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
47
|
M4096
|
Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 24 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
48
|
M5157
|
Genes up-regulated in comparison of macrophages versus macrophages exposed to L.donovani.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
49
|
M4102
|
Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus those stimulated at 24 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|
50
|
M8648
|
Genes down-regulated in bone marrow-derived macrophages: control versus stimulated with LPS.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.885E-3
|
3.074E-2
|
2.241E-1
|
1.000E0
|
2
|
200
|