|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
M2965
|
Genes down-regulated in T conv versus induced T reg with non-functional FOXP3 [GeneID=50943].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.566E-6
|
6.878E-3
|
4.922E-2
|
6.878E-3
|
3
|
183
|
2
|
M2879
|
Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
6.195E-5
|
2.206E-2
|
1.579E-1
|
4.454E-2
|
3
|
342
|
3
|
M5928
|
A subgroup of genes regulated by MYC - version 2 (v2).
|
MSigDB H: Hallmark Gene Sets (v6.0)
|
9.204E-5
|
2.206E-2
|
1.579E-1
|
6.618E-2
|
2
|
58
|
4
|
M4752
|
Genes down-regulated in rectal cancer patients resistant to radiotherapy (non-responders) relative to the sensitive ones (responders).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.322E-4
|
2.474E-2
|
1.770E-1
|
1.669E-1
|
2
|
92
|
5
|
M13108
|
Genes down-regulated in Wilm's tumor samples compared to fetal kidney.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
7.263E-4
|
2.474E-2
|
1.770E-1
|
5.222E-1
|
2
|
163
|
6
|
19261849-TableS4b
|
Human Endometrial Salvesen09 13genes
|
GeneSigDB
|
7.778E-4
|
2.474E-2
|
1.770E-1
|
5.592E-1
|
1
|
3
|
7
|
M4288
|
Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial, basal-like phenotype) confluency.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
8.845E-4
|
2.474E-2
|
1.770E-1
|
6.360E-1
|
2
|
180
|
8
|
M374
|
Genes up-regulated in B lymphocytes: naïve versus memory.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.041E-4
|
2.474E-2
|
1.770E-1
|
6.501E-1
|
2
|
182
|
9
|
M6807
|
Genes up-regulated in B lymphocytes treated by anti-HEL and expressing BCR [GeneID=613] fusions with: IgM versus IgMG.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
9.440E-4
|
2.474E-2
|
1.770E-1
|
6.787E-1
|
2
|
186
|
10
|
16585155-TableS1
|
Human Colon Watanabe06 214genes
|
GeneSigDB
|
1.005E-3
|
2.474E-2
|
1.770E-1
|
7.228E-1
|
2
|
192
|
11
|
M4216
|
Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 6 h versus the untreated cells at 6 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.047E-3
|
2.474E-2
|
1.770E-1
|
7.530E-1
|
2
|
196
|
12
|
M8345
|
Genes down-regulated in activated versus induced T reg cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.047E-3
|
2.474E-2
|
1.770E-1
|
7.530E-1
|
2
|
196
|
13
|
M7458
|
Genes down-regulated in CD4 [GeneID=920] T cells with STAT3 [GeneID=6774] knockout: medium versus IL6 [GeneID=3569].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.058E-3
|
2.474E-2
|
1.770E-1
|
7.606E-1
|
2
|
197
|
14
|
M4728
|
Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 8 h versus DCs stimulated with LPS (TLR4 agonist) and R848 for 8 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.069E-3
|
2.474E-2
|
1.770E-1
|
7.683E-1
|
2
|
198
|
15
|
M6104
|
Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 and IL4 [GeneID=7040;3565] (6h) versus IL4 [GeneID=3565] (6h).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.069E-3
|
2.474E-2
|
1.770E-1
|
7.683E-1
|
2
|
198
|
16
|
M5723
|
Genes up-regulated in comparison of NK cells treated with IL15 [GeneID=3567] versus untreated NK cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.079E-3
|
2.474E-2
|
1.770E-1
|
7.760E-1
|
2
|
199
|
17
|
M3027
|
Genes up-regulated in comparison of naive versus memory CD8 T cells (day 40+ following LCMV-Armstrong infection).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.079E-3
|
2.474E-2
|
1.770E-1
|
7.760E-1
|
2
|
199
|
18
|
M6033
|
Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (48h) versus untreated (48h).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.079E-3
|
2.474E-2
|
1.770E-1
|
7.760E-1
|
2
|
199
|
19
|
M9410
|
Genes up-regulated in NK cells: untreated versus poly(IC).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
20
|
M9486
|
Genes down-regulated in CD8 T effector cells during chronic infection with LCMV-Clone 13: day 6 versus day 8.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
21
|
M3591
|
Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with IL12 .
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
22
|
M3830
|
Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 2 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 2 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
23
|
M9523
|
Genes up-regulated in CD5 T cells at acute infection with LCMV-Armstrong: effectors at day 15 versus memory at day 30.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
24
|
M8332
|
Genes down-regulated in BCL6 [GeneID=604] low follicular helper T cells versus T conv cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
25
|
M3059
|
Genes down-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 intermediate [GeneID=10219].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
26
|
M9542
|
Genes up-regulated in macrophages: resting versus stimulated by IL4 [GeneID=3565].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
27
|
M6065
|
Genes up-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: TGFB1 [GeneID=7040] and IL-12 (6h) versus IL4 [GeneID=3565] (6h).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
28
|
M9384
|
Genes up-regulated in day 7 plasma cells versus day 40 memory B cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
29
|
M3594
|
Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h after stimulation with antigen-B7-1.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
30
|
M9419
|
Genes up-regulated after poly(IC) injection: CD8A [GeneID=925] dendritic cells versus NK cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
31
|
M3588
|
Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 24 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.474E-2
|
1.770E-1
|
7.838E-1
|
2
|
200
|
32
|
M14340
|
Genes down-regulated in MCF-7 cells (breast cancer) after knockdown of YBX1 [GeneID=4904] by RNAi.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.101E-3
|
2.474E-2
|
1.770E-1
|
7.915E-1
|
2
|
201
|
33
|
M2069
|
Genes selected in supervised analyses to discriminate cells expressing c-Myc [GeneID=4609] from control cells expressing GFP.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.156E-3
|
2.518E-2
|
1.802E-1
|
8.310E-1
|
2
|
206
|
34
|
M5042
|
Up-regulated genes in the canonical gene expression signature of the fibroblast core serum response (CSR) defined by the Stanford group.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.223E-3
|
2.587E-2
|
1.851E-1
|
8.797E-1
|
2
|
212
|
35
|
12970791-Table2b
|
Human Lymphoma Qiu03 13genes
|
GeneSigDB
|
1.296E-3
|
2.662E-2
|
1.905E-1
|
9.319E-1
|
1
|
5
|
36
|
M5635
|
Genes down-regulated in LNCaP cells (prostate cancer) after knockdown of SAM68 [GeneID=10657] by RNAi.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.555E-3
|
3.064E-2
|
2.192E-1
|
1.000E0
|
1
|
6
|
37
|
M12816
|
Genes down-regulated in MDA-MB-453 cells (class A ER(-) [GeneID=2099] breast cancer) after exposure to the androgen R1881 [PubChem=13766].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.577E-3
|
3.064E-2
|
2.192E-1
|
1.000E0
|
2
|
241
|
38
|
17145885-SuppTable2
|
Human Lung Kobayashi06 320genes
|
GeneSigDB
|
1.655E-3
|
3.132E-2
|
2.241E-1
|
1.000E0
|
2
|
247
|
39
|
M16010
|
Genes down-regulated in H1975 cells (non-small cell lung cancer, NSCLC) resistant to gefitinib [PubChem=123631] after treatment with EGFR inhibitor CL-387785 [PubChem=2776] for 24h.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.709E-3
|
3.150E-2
|
2.254E-1
|
1.000E0
|
2
|
251
|
40
|
19373655-Table3
|
Mouse Lymphoma Saez09 16genes
|
GeneSigDB
|
1.814E-3
|
3.181E-2
|
2.276E-1
|
1.000E0
|
1
|
7
|
41
|
18661203-Table3
|
Mouse Uterine Kashiwazaki08 9genes
|
GeneSigDB
|
1.814E-3
|
3.181E-2
|
2.276E-1
|
1.000E0
|
1
|
7
|
42
|
M679
|
G1 to S phase regulators significantly changed in DanG cells (pancreatic cancer) treated with Ly294002 [PubChem=3973], a phosphoinositide 3-kinase (PI3K) inhibitor.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.073E-3
|
3.466E-2
|
2.480E-1
|
1.000E0
|
1
|
8
|
43
|
16707422-tableS3c
|
Human Prostate Hendriksen06 11genes
|
GeneSigDB
|
2.073E-3
|
3.466E-2
|
2.480E-1
|
1.000E0
|
1
|
8
|
44
|
M16807
|
Genes required for both proliferation and CTNNB1 [GeneID=1499] activity in DLD-1 cell (colon cancer with APC [GeneID=324] deletions).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.332E-3
|
3.811E-2
|
2.727E-1
|
1.000E0
|
1
|
9
|
45
|
M11171
|
Genes up-regulated in fibroblasts expressing mutant forms of ERCC3 [GeneID=2071] after UV irradiation.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.574E-3
|
4.049E-2
|
2.898E-1
|
1.000E0
|
2
|
309
|
46
|
M10504
|
Genes down-regulated in H1299 cells (non-small cell lung cancer, NSCLC) expressing the Y144F mutant form of FHIT [GeneID=2272].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.591E-3
|
4.049E-2
|
2.898E-1
|
1.000E0
|
1
|
10
|
47
|
M2156
|
Genes up-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChem=5757] treatment.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.825E-3
|
4.322E-2
|
3.093E-1
|
1.000E0
|
2
|
324
|
48
|
M854
|
Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.894E-3
|
4.335E-2
|
3.102E-1
|
1.000E0
|
2
|
328
|
49
|
M7079
|
The 'core ESC-like gene module': genes coordinately up-regulated in a compendium of mouse embryonic stem cells (ESC) which are shared with the human ESC-like module.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.017E-3
|
4.427E-2
|
3.168E-1
|
1.000E0
|
2
|
335
|
50
|
18662380-S3-AURKA
|
Human Breast Wirapati08 355genes AURKA Module
|
GeneSigDB
|
3.178E-3
|
4.570E-2
|
3.270E-1
|
1.000E0
|
2
|
344
|