|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
10698177
|
Role of the Y1 receptor in the regulation of neuropeptide Y-mediated feeding: comparison of wild-type, Y1 receptor-deficient, and Y5 receptor-deficient mice.
|
Pubmed
|
8.862E-21
|
4.932E-18
|
3.744E-17
|
9.863E-18
|
5
|
5
|
2
|
12007534
|
Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status.
|
Pubmed
|
8.862E-21
|
4.932E-18
|
3.744E-17
|
9.863E-18
|
5
|
5
|
3
|
17325259
|
Association studies of BMI and type 2 diabetes in the neuropeptide Y pathway: a possible role for NPY2R as a candidate gene for type 2 diabetes in men.
|
Pubmed
|
5.317E-20
|
1.973E-17
|
1.498E-16
|
5.918E-17
|
5
|
6
|
4
|
17948870
|
Chromosome 4q31-34 panic disorder risk locus: association of neuropeptide Y Y5 receptor variants.
|
Pubmed
|
1.692E-16
|
2.354E-14
|
1.787E-13
|
1.883E-13
|
4
|
4
|
5
|
19481128
|
Cloning and characterization of rabbit neuropeptide Y receptor subtypes.
|
Pubmed
|
1.692E-16
|
2.354E-14
|
1.787E-13
|
1.883E-13
|
4
|
4
|
6
|
24985894
|
Neuropeptide Y-stimulated [(35) S]GTPγs functional binding is reduced in the hippocampus after kainate-induced seizures in mice.
|
Pubmed
|
1.692E-16
|
2.354E-14
|
1.787E-13
|
1.883E-13
|
4
|
4
|
7
|
18828811
|
Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.
|
Pubmed
|
1.692E-16
|
2.354E-14
|
1.787E-13
|
1.883E-13
|
4
|
4
|
8
|
23011592
|
Neuropeptide Y1 receptor in immune cells regulates inflammation and insulin resistance associated with diet-induced obesity.
|
Pubmed
|
1.692E-16
|
2.354E-14
|
1.787E-13
|
1.883E-13
|
4
|
4
|
9
|
18577758
|
Dissociation of heterotrimeric g proteins in cells.
|
Pubmed
|
9.741E-15
|
1.205E-12
|
9.146E-12
|
1.084E-11
|
6
|
179
|
10
|
2834384
|
Presence of three distinct molecular species of Gi protein alpha subunit. Structure of rat cDNAs and human genomic DNAs.
|
Pubmed
|
1.527E-13
|
1.700E-11
|
1.291E-10
|
1.700E-10
|
5
|
75
|
11
|
16100526
|
The regulation of veratridine-stimulated electrogenic ion transport in mouse colon by neuropeptide Y (NPY), Y1 and Y2 receptors.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
12
|
9722158
|
Complementary and overlapping expression of Y1, Y2 and Y5 receptors in the developing and adult mouse nervous system.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
13
|
19459152
|
NPY revealed as a critical modulator of osteoblast function in vitro: new insights into the role of Y1 and Y2 receptors.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
14
|
1321422
|
Cloned human neuropeptide Y receptor couples to two different second messenger systems.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
15
|
16198492
|
Y1-receptors regulate the expression of Y2-receptors in distinct mouse forebrain areas.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
16
|
11906964
|
Neuropeptide Y, Y1, Y2 and Y4 receptors mediate Y agonist responses in isolated human colon mucosa.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
17
|
25471570
|
Actions of NPY, and its Y1 and Y2 receptors on pulsatile growth hormone secretion during the fed and fasted state.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
18
|
19759915
|
Variants in neuropeptide Y receptor 1 and 5 are associated with nutrient-specific food intake and are under recent selection in Europeans.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
19
|
11579129
|
Distinct roles of the Y1 and Y2 receptors on neuropeptide Y-induced sensitization to sedation.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
20
|
21452195
|
Characterization of NPY Y2 receptor protein expression in the mouse brain. II. Coexistence with NPY, the Y1 receptor, and other neurotransmitter-related molecules.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
21
|
22289084
|
NPY controls fear conditioning and fear extinction by combined action on Yâ?? and Yâ?? receptors.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
22
|
16891622
|
Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
23
|
12665544
|
The use of bioluminescence resonance energy transfer 2 to study neuropeptide Y receptor agonist-induced beta-arrestin 2 interaction.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
24
|
9001438
|
Neuropeptide Y receptor subtypes.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
25
|
10720571
|
Evolution of the neuropeptide Y receptor family: gene and chromosome duplications deduced from the cloning and mapping of the five receptor subtype genes in pig.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
26
|
7559383
|
Cloning and functional expression of a cDNA encoding a human type 2 neuropeptide Y receptor.
|
Pubmed
|
2.154E-12
|
9.221E-11
|
7.001E-10
|
2.398E-9
|
3
|
3
|
27
|
19058789
|
A common variant in DRD3 receptor is associated with autism spectrum disorder.
|
Pubmed
|
2.433E-12
|
1.003E-10
|
7.613E-10
|
2.707E-9
|
5
|
129
|
28
|
7493937
|
Cloning of a human receptor of the NPY receptor family with high affinity for pancreatic polypeptide and peptide YY.
|
Pubmed
|
8.616E-12
|
3.307E-10
|
2.511E-9
|
9.589E-9
|
3
|
4
|
29
|
23395170
|
Arcuate NPY controls sympathetic output and BAT function via a relay of tyrosine hydroxylase neurons in the PVN.
|
Pubmed
|
8.616E-12
|
3.307E-10
|
2.511E-9
|
9.589E-9
|
3
|
4
|
30
|
20468064
|
Association study of 182 candidate genes in anorexia nervosa.
|
Pubmed
|
1.390E-11
|
5.156E-10
|
3.915E-9
|
1.547E-8
|
5
|
182
|
31
|
19593212
|
Novel genetic variants contributing to left ventricular hypertrophy: the HyperGEN study.
|
Pubmed
|
7.538E-11
|
2.706E-9
|
2.055E-8
|
8.389E-8
|
3
|
7
|
32
|
9417917
|
Neuropeptide Y receptor genes mapped in human and mouse: receptors with high affinity for pancreatic polypeptide are not clustered with receptors specific for neuropeptide Y and peptide YY.
|
Pubmed
|
2.584E-10
|
8.987E-9
|
6.823E-8
|
2.876E-7
|
3
|
10
|
33
|
19874574
|
Genetical genomic determinants of alcohol consumption in rats and humans.
|
Pubmed
|
1.912E-9
|
6.448E-8
|
4.896E-7
|
2.128E-6
|
4
|
130
|
34
|
14525913
|
Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
35
|
12084524
|
Neuropeptide Y Y1 and neuropeptide Y Y2 receptors in human cardiovascular tissues.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
36
|
21923762
|
NPY receptor subtype specification for behavioral adaptive strategies during limited food access.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
37
|
22768253
|
Y1 and Y5 receptors are both required for the regulation of food intake and energy homeostasis in mice.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
38
|
20471432
|
Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
39
|
23838112
|
Expressions of neuropeptide Y and Y1 receptor in subcutaneous and visceral fat tissues in normal weight and obese humans and their correlations with clinical parameters and peripheral metabolic factors.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
40
|
21745157
|
Functional reconstitution of human neuropeptide Y (NPY) Y(2) and Y(4) receptors in Sf9 insect cells.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
41
|
12372697
|
Langerhans cell expression of neuropeptide Y and peptide YY.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
42
|
15331560
|
Studies of the peptide YY and neuropeptide Y2 receptor genes in relation to human obesity and obesity-related traits.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
43
|
27244241
|
Cell type specificity of neurovascular coupling in cerebral cortex.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
44
|
16190896
|
The anti-epileptic actions of neuropeptide Y in the hippocampus are mediated by Y and not Y receptors.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
45
|
25924821
|
Unwinding of the C-Terminal Residues of Neuropeptide Y is critical for Yâ?? Receptor Binding and Activation.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
46
|
19699258
|
Neuropeptide Y modulates steroid production of human adrenal H295R cells through Y1 receptors.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
47
|
16339211
|
Activation of the Y1 receptor by neuropeptide Y regulates the growth of prostate cancer cells.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
48
|
23733357
|
Neuropeptide Y modulates fracture healing through Y1 receptor signaling.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
49
|
24121255
|
Association of age at onset in Huntington disease with functional promoter variations in NPY and NPY2R.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|
50
|
14755515
|
Characterization of neuropeptide Y Y2 and Y5 receptor expression in the mouse hypothalamus.
|
Pubmed
|
2.057E-8
|
2.100E-7
|
1.594E-6
|
2.289E-5
|
2
|
2
|