Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc219_7, positive side

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1: GO: Molecular Function [Display Chart] 7 input genes in category / 11 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:1990825 sequence-specific mRNA binding 3.618E-7 3.980E-6 1.202E-5 3.980E-6 2 3
2 GO:0003729 mRNA binding 2.953E-5 1.321E-4 3.990E-4 3.248E-4 3 179
3 GO:0036002 pre-mRNA binding 3.604E-5 1.321E-4 3.990E-4 3.964E-4 2 25
4 GO:0043274 phospholipase binding 8.225E-3 2.055E-2
6.206E-2
9.047E-2
 1 22
5 GO:0070717 poly-purine tract binding 9.342E-3 2.055E-2
6.206E-2
1.028E-1
 1 25

2: GO: Biological Process [Display Chart] 7 input genes in category / 116 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006369 termination of RNA polymerase II transcription 7.247E-12 8.406E-10 4.485E-9 8.406E-10 5 62
2 GO:0048024 regulation of mRNA splicing, via spliceosome 1.457E-11 8.450E-10 4.508E-9 1.690E-9 5 71
3 GO:0031124 mRNA 3'-end processing 5.492E-11 1.381E-9 7.370E-9 6.371E-9 5 92
4 GO:0006353 DNA-templated transcription, termination 9.294E-11 1.381E-9 7.370E-9 1.078E-8 5 102
5 GO:0048025 negative regulation of mRNA splicing, via spliceosome 1.041E-10 1.381E-9 7.370E-9 1.208E-8 4 26
6 GO:0006406 mRNA export from nucleus 1.130E-10 1.381E-9 7.370E-9 1.311E-8 5 106
7 GO:0071427 mRNA-containing ribonucleoprotein complex export from nucleus 1.130E-10 1.381E-9 7.370E-9 1.311E-8 5 106
8 GO:0000398 mRNA splicing, via spliceosome 1.269E-10 1.381E-9 7.370E-9 1.472E-8 6 305
9 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 1.269E-10 1.381E-9 7.370E-9 1.472E-8 6 305
10 GO:0043484 regulation of RNA splicing 1.303E-10 1.381E-9 7.370E-9 1.511E-8 5 109
11 GO:0000375 RNA splicing, via transesterification reactions 1.373E-10 1.381E-9 7.370E-9 1.592E-8 6 309
12 GO:0050684 regulation of mRNA processing 1.429E-10 1.381E-9 7.370E-9 1.658E-8 5 111
13 GO:0031123 RNA 3'-end processing 2.123E-10 1.588E-9 8.473E-9 2.463E-8 5 120
14 GO:0006405 RNA export from nucleus 2.123E-10 1.588E-9 8.473E-9 2.463E-8 5 120
15 GO:0071426 ribonucleoprotein complex export from nucleus 2.123E-10 1.588E-9 8.473E-9 2.463E-8 5 120
16 GO:0033119 negative regulation of RNA splicing 2.190E-10 1.588E-9 8.473E-9 2.541E-8 4 31
17 GO:0071166 ribonucleoprotein complex localization 2.406E-10 1.642E-9 8.761E-9 2.792E-8 5 123
18 GO:1903311 regulation of mRNA metabolic process 3.186E-10 2.053E-9 1.095E-8 3.696E-8 5 130
19 GO:0050686 negative regulation of mRNA processing 4.594E-10 2.805E-9 1.496E-8 5.329E-8 4 37
20 GO:0008380 RNA splicing 6.702E-10 3.755E-9 2.003E-8 7.775E-8 6 402
21 GO:0051028 mRNA transport 6.797E-10 3.755E-9 2.003E-8 7.885E-8 5 151
22 GO:1903312 negative regulation of mRNA metabolic process 9.435E-10 4.975E-9 2.654E-8 1.094E-7 4 44
23 GO:0050657 nucleic acid transport 1.604E-9 7.753E-9 4.136E-8 1.861E-7 5 179
24 GO:0050658 RNA transport 1.604E-9 7.753E-9 4.136E-8 1.861E-7 5 179
25 GO:0051236 establishment of RNA localization 1.744E-9 8.093E-9 4.318E-8 2.023E-7 5 182
26 GO:0006397 mRNA processing 1.923E-9 8.579E-9 4.577E-8 2.231E-7 6 479
27 GO:0051168 nuclear export 2.054E-9 8.824E-9 4.708E-8 2.382E-7 5 188
28 GO:0006403 RNA localization 3.942E-9 1.614E-8 8.611E-8 4.572E-7 5 214
29 GO:0015931 nucleobase-containing compound transport 4.035E-9 1.614E-8 8.611E-8 4.681E-7 5 215
30 GO:0006913 nucleocytoplasmic transport 2.587E-7 1.000E-6 5.337E-6 3.001E-5 5 494
31 GO:0006376 mRNA splice site selection 5.242E-5 1.961E-4 1.046E-3 6.081E-3 2 30
32 GO:0000381 regulation of alternative mRNA splicing, via spliceosome 7.583E-5 2.749E-4 1.467E-3 8.797E-3 2 36
33 GO:0000380 alternative mRNA splicing, via spliceosome 1.299E-4 4.565E-4 2.435E-3 1.506E-2 2 47
34 GO:0000245 spliceosomal complex assembly 1.914E-4 6.530E-4 3.484E-3 2.220E-2 2 57
35 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 2.253E-3 7.469E-3 3.985E-2
2.614E-1
 1 6
36 GO:0022618 ribonucleoprotein complex assembly 2.513E-3 8.096E-3 4.319E-2
2.915E-1
 2 208
37 GO:2000675 negative regulation of type B pancreatic cell apoptotic process 2.629E-3 8.241E-3 4.397E-2
3.049E-1
 1 7
38 GO:0071826 ribonucleoprotein complex subunit organization 2.756E-3 8.412E-3 4.488E-2
3.197E-1
 2 218
39 GO:2000794 regulation of epithelial cell proliferation involved in lung morphogenesis 3.004E-3 8.934E-3 4.766E-2
3.484E-1
 1 8
40 GO:1990403 embryonic brain development 3.379E-3 9.331E-3 4.978E-2
3.919E-1
 1 9
41 GO:0045617 negative regulation of keratinocyte differentiation 3.379E-3 9.331E-3 4.978E-2
3.919E-1
 1 9
42 GO:0021796 cerebral cortex regionalization 3.379E-3 9.331E-3 4.978E-2
3.919E-1
 1 9
43 GO:0060502 epithelial cell proliferation involved in lung morphogenesis 4.128E-3 1.114E-2
5.941E-2
4.788E-1
 1 11
44 GO:2000674 regulation of type B pancreatic cell apoptotic process 5.251E-3 1.354E-2
7.222E-2
6.092E-1
 1 14
45 GO:0045605 negative regulation of epidermal cell differentiation 5.251E-3 1.354E-2
7.222E-2
6.092E-1
 1 14
46 GO:0021978 telencephalon regionalization 6.000E-3 1.513E-2
8.072E-2
6.959E-1
 1 16
47 GO:0097050 type B pancreatic cell apoptotic process 6.373E-3 1.573E-2
8.392E-2
7.393E-1
 1 17
48 GO:0048026 positive regulation of mRNA splicing, via spliceosome 6.747E-3 1.631E-2
8.699E-2
7.827E-1
 1 18
49 GO:0045683 negative regulation of epidermis development 7.121E-3 1.686E-2
8.994E-2
8.260E-1
 1 19
50 GO:0051412 response to corticosterone 1.011E-2 2.345E-2
1.251E-1
1.000E0
 1 27
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 7 input genes in category / 5 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016607 nuclear speck 3.919E-5 1.960E-4 4.474E-4 1.960E-4 3 201
2 GO:0016604 nuclear body 2.283E-4 5.709E-4 1.303E-3 1.142E-3 3 364
3 GO:0005637 nuclear inner membrane 2.039E-2 3.398E-2
7.759E-2
1.019E-1
 1 56

4: Human Phenotype [Display Chart] 0 input genes in category / 0 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 6 input genes in category / 135 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 7 input genes in category / 15 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF00076 RRM 1 Pfam 1.209E-11 8.335E-11 2.766E-10 1.813E-10 6 208
2 SM00360 RRM SMART 1.562E-11 8.335E-11 2.766E-10 2.344E-10 6 217
3 IPR000504 RRM dom InterPro 2.053E-11 8.335E-11 2.766E-10 3.079E-10 6 227
4 PS50102 RRM PROSITE 2.223E-11 8.335E-11 2.766E-10 3.334E-10 6 230
5 3.30.70.330 - Gene3D 3.178E-11 9.535E-11 3.164E-10 4.768E-10 6 244
6 IPR012677 Nucleotide-bd a/b plait InterPro 4.454E-11 1.114E-10 3.695E-10 6.681E-10 6 258
7 IPR029813 FosB InterPro 3.736E-4 8.006E-4 2.657E-3 5.604E-3 1 1
8 IPR000837 AP-1 InterPro 3.358E-3 6.297E-3 2.089E-2
5.038E-2
 1 9
9 PF07716 bZIP 2 Pfam 6.335E-3 1.056E-2 3.504E-2
9.503E-2
 1 17
10 PF00170 bZIP 1 Pfam 1.264E-2 1.874E-2
6.219E-2
1.895E-1
 1 34
11 IPR008917 TF DNA-bd InterPro 1.374E-2 1.874E-2
6.219E-2
2.062E-1
 1 37
12 SM00338 BRLZ SMART 1.927E-2 2.001E-2
6.638E-2
2.891E-1
 1 52
13 PS00036 BZIP BASIC PROSITE 1.964E-2 2.001E-2
6.638E-2
2.946E-1
 1 53
14 PS50217 BZIP PROSITE 1.964E-2 2.001E-2
6.638E-2
2.946E-1
 1 53
15 IPR004827 bZIP InterPro 2.001E-2 2.001E-2
6.638E-2
3.001E-1
 1 54
Show 10 more annotations

7: Pathway [Display Chart] 7 input genes in category / 17 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269692 mRNA 3'-end processing BioSystems: REACTOME 5.880E-11 3.975E-10 1.367E-9 9.997E-10 5 63
2 1269690 mRNA Splicing - Major Pathway BioSystems: REACTOME 7.570E-11 3.975E-10 1.367E-9 1.287E-9 6 188
3 1269689 mRNA Splicing BioSystems: REACTOME 9.747E-11 3.975E-10 1.367E-9 1.657E-9 6 196
4 1269686 Cleavage of Growing Transcript in the Termination Region BioSystems: REACTOME 1.169E-10 3.975E-10 1.367E-9 1.988E-9 5 72
5 1269685 RNA Polymerase II Transcription Termination BioSystems: REACTOME 1.169E-10 3.975E-10 1.367E-9 1.988E-9 5 72
6 1269694 Transport of Mature mRNA derived from an Intron-Containing Transcript BioSystems: REACTOME 1.543E-10 4.372E-10 1.504E-9 2.623E-9 5 76
7 1269693 Transport of Mature Transcript to Cytoplasm BioSystems: REACTOME 3.266E-10 7.933E-10 2.729E-9 5.553E-9 5 88
8 1269688 Processing of Capped Intron-Containing Pre-mRNA BioSystems: REACTOME 4.051E-10 8.608E-10 2.961E-9 6.887E-9 6 248
9 125136 Spliceosome BioSystems: KEGG 2.767E-9 5.226E-9 1.797E-8 4.703E-8 5 134
10 1269675 RNA Polymerase II Transcription BioSystems: REACTOME 7.212E-9 1.226E-8 4.217E-8 1.226E-7 5 162
11 377873 Herpes simplex infection BioSystems: KEGG 1.595E-6 2.466E-6 8.481E-6 2.712E-5 4 185
12 546258 Cocaine addiction BioSystems: KEGG 2.723E-2 3.848E-2
1.324E-1
4.630E-1
 1 49
13 1269691 mRNA Splicing - Minor Pathway BioSystems: REACTOME 2.943E-2 3.848E-2
1.324E-1
5.003E-1
 1 53
14 547607 Amphetamine addiction BioSystems: KEGG 3.762E-2 4.568E-2
1.571E-1
6.396E-1
 1 68
Show 9 more annotations

8: Pubmed [Display Chart] 7 input genes in category / 478 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19857271 The SR protein family. Pubmed 3.907E-18 1.868E-15 1.260E-14 1.868E-15 5 9
2 20516191 A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). Pubmed 3.990E-17 9.537E-15 6.436E-14 1.907E-14 5 13
3 23818142 Splicing factor TRA2B is required for neural progenitor survival. Pubmed 2.656E-16 4.232E-14 2.856E-13 1.270E-13 5 18
4 15009664 Tau exon 10, whose missplicing causes frontotemporal dementia, is regulated by an intricate interplay of cis elements and trans factors. Pubmed 8.288E-14 9.905E-12 6.683E-11 3.962E-11 4 10
5 14559993 Regulation of alternative splicing by SRrp86 and its interacting proteins. Pubmed 1.296E-13 1.239E-11 8.359E-11 6.194E-11 5 57
6 12226669 Comprehensive proteomic analysis of the human spliceosome. Pubmed 3.607E-12 2.874E-10 1.939E-9 1.724E-9 5 109
7 17332742 Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes. Pubmed 4.737E-12 3.235E-10 2.183E-9 2.265E-9 5 115
8 23084401 The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus. Pubmed 3.333E-11 1.991E-9 1.344E-8 1.593E-8 5 169
9 22365833 Dynamic protein-protein interaction wiring of the human spliceosome. Pubmed 7.226E-11 3.275E-9 2.210E-8 3.454E-8 5 197
10 1577277 SR proteins: a conserved family of pre-mRNA splicing factors. Pubmed 7.538E-11 3.275E-9 2.210E-8 3.603E-8 3 6
11 17361132 Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements. Pubmed 7.538E-11 3.275E-9 2.210E-8 3.603E-8 3 6
12 29055695 Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Pubmed 1.445E-10 5.758E-9 3.885E-8 6.909E-8 4 56
13 26641092 The Activation-Induced Assembly of an RNA/Protein Interactome Centered on the Splicing Factor U2AF2 Regulates Gene Expression in Human CD4 T Cells. Pubmed 1.913E-10 6.724E-9 4.538E-8 9.143E-8 5 239
14 8208298 A serine kinase regulates intracellular localization of splicing factors in the cell cycle. Pubmed 2.110E-10 6.724E-9 4.538E-8 1.009E-7 3 8
15 9671816 SAF-B protein couples transcription and pre-mRNA splicing to SAR/MAR elements. Pubmed 2.110E-10 6.724E-9 4.538E-8 1.009E-7 3 8
16 16033648 A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain. Pubmed 4.634E-10 1.385E-8 9.343E-8 2.215E-7 5 285
17 25948554 Disruption of the lamin A and matrin-3 interaction by myopathic LMNA mutations. Pubmed 1.304E-9 3.601E-8 2.430E-7 6.233E-7 4 96
18 27545878 SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Pubmed 1.356E-9 3.601E-8 2.430E-7 6.482E-7 5 353
19 24999758 Proteomic Analysis of the EWS-Fli-1 Interactome Reveals the Role of the Lysosome in EWS-Fli-1 Turnover. Pubmed 3.436E-9 8.213E-8 5.542E-7 1.643E-6 5 425
20 21081503 RioK1, a new interactor of protein arginine methyltransferase 5 (PRMT5), competes with pICln for binding and modulates PRMT5 complex composition and substrate specificity. Pubmed 3.436E-9 8.213E-8 5.542E-7 1.643E-6 5 425
21 7651409 A subset of SR proteins activates splicing of the cardiac troponin T alternative exon by direct interactions with an exonic enhancer. Pubmed 2.879E-8 5.505E-7 3.715E-6 1.376E-5 2 2
22 20639886 Global analysis reveals SRp20- and SRp75-specific mRNPs in cycling and neural cells. Pubmed 2.879E-8 5.505E-7 3.715E-6 1.376E-5 2 2
23 20685659 Serine- and arginine-rich proteins 55 and 75 (SRp55 and SRp75) induce production of HIV-1 vpr mRNA by inhibiting the 5'-splice site of exon 3. Pubmed 2.879E-8 5.505E-7 3.715E-6 1.376E-5 2 2
24 22436691 The RNA-binding landscapes of two SR proteins reveal unique functions and binding to diverse RNA classes. Pubmed 2.879E-8 5.505E-7 3.715E-6 1.376E-5 2 2
25 12531473 Human transformer 2beta and SRp55 interact with a calcitonin-specific splice enhancer. Pubmed 2.879E-8 5.505E-7 3.715E-6 1.376E-5 2 2
26 19608861 Lysine acetylation targets protein complexes and co-regulates major cellular functions. Pubmed 3.171E-8 5.830E-7 3.934E-6 1.516E-5 3 38
27 7556075 Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. Pubmed 8.637E-8 1.475E-6 9.950E-6 4.129E-5 2 3
28 28373129 Role of spliceosome proteins in the regulation of glucocorticoid receptor isoforms by cortisol and dehydroepiandrosterone. Pubmed 8.637E-8 1.475E-6 9.950E-6 4.129E-5 2 3
29 22205602 Spliceosome protein (SRp) regulation of glucocorticoid receptor isoforms and glucocorticoid response in human trabecular meshwork cells. Pubmed 1.727E-7 2.580E-6 1.741E-5 8.257E-5 2 4
30 10809668 Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon-exon junctions. Pubmed 1.727E-7 2.580E-6 1.741E-5 8.257E-5 2 4
31 10823932 A mammalian germ cell-specific RNA-binding protein interacts with ubiquitously expressed proteins involved in splice site selection. Pubmed 1.727E-7 2.580E-6 1.741E-5 8.257E-5 2 4
32 11875052 SRp30c-dependent stimulation of survival motor neuron (SMN) exon 7 inclusion is facilitated by a direct interaction with hTra2 beta 1. Pubmed 1.727E-7 2.580E-6 1.741E-5 8.257E-5 2 4
33 26167880 SR protein kinases promote splicing of nonconsensus introns. Pubmed 2.687E-7 3.822E-6 2.579E-5 1.284E-4 4 361
34 10757789 Identification and characterization of a novel serine-arginine-rich splicing regulatory protein. Pubmed 2.879E-7 3.822E-6 2.579E-5 1.376E-4 2 5
35 2030943 A differentially expressed murine RNA encoding a protein with similarities to two types of nucleic acid binding motifs. Pubmed 2.879E-7 3.822E-6 2.579E-5 1.376E-4 2 5
36 8617202 The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. Pubmed 2.879E-7 3.822E-6 2.579E-5 1.376E-4 2 5
37 20376328 Assessment of SNPs associated with the human glucocorticoid receptor in primary open-angle glaucoma and steroid responders. Pubmed 4.318E-7 5.431E-6 3.665E-5 2.064E-4 2 6
38 25416801 HIV-1 transcription is regulated by splicing factor SRSF1. Pubmed 4.318E-7 5.431E-6 3.665E-5 2.064E-4 2 6
39 15169763 Distinct sequence motifs within the 68-kDa subunit of cleavage factor Im mediate RNA binding, protein-protein interactions, and subcellular localization. Pubmed 6.044E-7 7.408E-6 4.999E-5 2.889E-4 2 7
40 20508642 ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes. Pubmed 7.214E-7 8.620E-6 5.817E-5 3.448E-4 3 106
41 9447963 Sip1, a novel RS domain-containing protein essential for pre-mRNA splicing. Pubmed 8.058E-7 9.171E-6 6.188E-5 3.852E-4 2 8
42 10390541 SR protein-specific kinase 1 is highly expressed in testis and phosphorylates protamine 1. Pubmed 8.058E-7 9.171E-6 6.188E-5 3.852E-4 2 8
43 10983978 Direct coupling of transcription and mRNA processing through the thermogenic coactivator PGC-1. Pubmed 1.295E-6 1.439E-5 9.712E-5 6.189E-4 2 10
44 26581985 Identification of Viral and Host Proteins That Interact with Murine Gammaherpesvirus 68 Latency-Associated Nuclear Antigen during Lytic Replication: a Role for Hsc70 in Viral Replication. Pubmed 1.582E-6 1.681E-5 1.134E-4 7.564E-4 2 11
45 14729963 Human RNPS1 and its associated factors: a versatile alternative pre-mRNA splicing regulator in vivo. Pubmed 1.582E-6 1.681E-5 1.134E-4 7.564E-4 2 11
46 9472028 SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells. Pubmed 1.899E-6 1.973E-5 1.331E-4 9.076E-4 2 12
47 28225217 Proteomic analysis of the cullin 4B interactome using proximity-dependent biotinylation in living cells. Pubmed 2.180E-6 2.218E-5 1.496E-4 1.042E-3 3 153
48 10749975 RBMY, a probable human spermatogenesis factor, and other hnRNP G proteins interact with Tra2beta and affect splicing. Pubmed 2.244E-6 2.234E-5 1.508E-4 1.073E-3 2 13
49 26336360 Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis. Pubmed 2.312E-6 2.255E-5 1.522E-4 1.105E-3 3 156
50 16159877 Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin. Pubmed 2.993E-6 2.861E-5 1.931E-4 1.431E-3 3 170
Show 45 more annotations

9: Interaction [Display Chart] 7 input genes in category / 405 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:SREK1 SREK1 interactions 8.243E-14 3.338E-11 2.197E-10 3.338E-11 6 87
2 int:SRSF1 SRSF1 interactions 1.147E-11 2.323E-9 1.529E-8 4.647E-9 6 195
3 int:PPIE PPIE interactions 2.016E-11 2.722E-9 1.792E-8 8.166E-9 6 214
4 int:SRSF6 SRSF6 interactions 3.246E-11 3.286E-9 2.163E-8 1.314E-8 5 79
5 int:SRSF9 SRSF9 interactions 5.317E-11 4.307E-9 2.835E-8 2.153E-8 5 87
6 int:SRSF2 SRSF2 interactions 6.189E-10 4.177E-8 2.750E-7 2.506E-7 5 141
7 int:U2AF2 U2AF2 interactions 8.041E-10 4.315E-8 2.841E-7 3.257E-7 6 394
8 int:SRSF7 SRSF7 interactions 9.353E-10 4.315E-8 2.841E-7 3.788E-7 5 153
9 int:SRSF3 SRSF3 interactions 1.066E-9 4.315E-8 2.841E-7 4.315E-7 5 157
10 int:SF3A2 SF3A2 interactions 1.066E-9 4.315E-8 2.841E-7 4.315E-7 5 157
11 int:MAGOH MAGOH interactions 3.178E-9 1.170E-7 7.702E-7 1.287E-6 5 195
12 int:TRA2B TRA2B interactions 4.189E-9 1.414E-7 9.305E-7 1.696E-6 5 206
13 int:EIF4A3 EIF4A3 interactions 2.174E-8 6.772E-7 4.458E-6 8.804E-6 5 286
14 int:RBMY1A1 RBMY1A1 interactions 5.020E-8 1.452E-6 9.558E-6 2.033E-5 3 21
15 int:RIOK1 RIOK1 interactions 2.435E-7 6.163E-6 4.057E-5 9.861E-5 5 464
16 int:SRPK2 SRPK2 interactions 2.435E-7 6.163E-6 4.057E-5 9.861E-5 5 464
17 int:CLK1 CLK1 interactions 3.084E-7 7.347E-6 4.836E-5 1.249E-4 4 174
18 int:RNPS1 RNPS1 interactions 6.304E-7 1.418E-5 9.336E-5 2.553E-4 4 208
19 int:PRPF38A PRPF38A interactions 6.921E-7 1.475E-5 9.710E-5 2.803E-4 3 49
20 int:SNRNP70 SNRNP70 interactions 8.328E-7 1.686E-5 1.110E-4 3.373E-4 4 223
21 int:SRPK1 SRPK1 interactions 1.379E-6 2.659E-5 1.750E-4 5.583E-4 4 253
22 int:SRPK3 SRPK3 interactions 1.488E-6 2.740E-5 1.803E-4 6.027E-4 3 63
23 int:SRSF4 SRSF4 interactions 1.714E-6 3.018E-5 1.987E-4 6.941E-4 3 66
24 int:BARD1 BARD1 interactions 2.065E-6 3.485E-5 2.294E-4 8.364E-4 4 280
25 int:RNF31 RNF31 interactions 2.903E-6 4.702E-5 3.095E-4 1.176E-3 4 305
26 int:SRSF10 SRSF10 interactions 4.095E-6 6.378E-5 4.199E-4 1.658E-3 3 88
27 int:SRSF11 SRSF11 interactions 4.838E-6 7.257E-5 4.777E-4 1.959E-3 3 93
28 int:SNIP1 SNIP1 interactions 6.392E-6 9.245E-5 6.086E-4 2.589E-3 3 102
29 int:S100A9 S100A9 interactions 6.975E-6 9.741E-5 6.412E-4 2.825E-3 3 105
30 int:SRSF5 SRSF5 interactions 1.265E-5 1.708E-4 1.124E-3 5.124E-3 3 128
31 int:CUL4B CUL4B interactions 1.839E-5 2.376E-4 1.564E-3 7.447E-3 4 486
32 int:CD2BP2 CD2BP2 interactions 1.877E-5 2.376E-4 1.564E-3 7.603E-3 3 146
33 int:HNRNPK HNRNPK interactions 1.993E-5 2.425E-4 1.596E-3 8.070E-3 4 496
34 int:TADA2A TADA2A interactions 2.036E-5 2.425E-4 1.596E-3 8.244E-3 3 150
35 int:SRRM1 SRRM1 interactions 3.119E-5 3.609E-4 2.376E-3 1.263E-2 3 173
36 int:LUC7L2 LUC7L2 interactions 3.935E-5 4.427E-4 2.914E-3 1.594E-2 3 187
37 int:TRA2A TRA2A interactions 6.650E-5 7.279E-4 4.791E-3 2.693E-2 3 223
38 int:TRMT112 TRMT112 interactions 9.358E-5 9.718E-4 6.397E-3 3.790E-2 2 38
39 int:RBMS2 RBMS2 interactions 9.358E-5 9.718E-4 6.397E-3 3.790E-2 2 38
40 int:PAXIP1 PAXIP1 interactions 1.123E-4 1.137E-3 7.483E-3 4.547E-2 3 266
41 int:NFIA NFIA interactions 1.376E-4 1.327E-3 8.732E-3
5.572E-2
 2 46
42 int:NFX1 NFX1 interactions 1.376E-4 1.327E-3 8.732E-3
5.572E-2
 2 46
43 int:SCAF11 SCAF11 interactions 1.499E-4 1.412E-3 9.292E-3
6.070E-2
 2 48
44 int:EIF4H EIF4H interactions 2.269E-4 2.088E-3 1.375E-2
9.188E-2
 2 59
45 int:DDX47 DDX47 interactions 2.588E-4 2.321E-3 1.528E-2
1.048E-1
 2 63
46 int:SUZ12 SUZ12 interactions 2.636E-4 2.321E-3 1.528E-2
1.068E-1
 3 355
47 int:SMU1 SMU1 interactions 3.015E-4 2.598E-3 1.710E-2
1.221E-1
 2 68
48 int:VASN VASN interactions 3.381E-4 2.852E-3 1.878E-2
1.369E-1
 2 72
49 int:PPARGC1A PPARGC1A interactions 3.767E-4 3.113E-3 2.049E-2
1.526E-1
 2 76
50 int:SLC3A2 SLC3A2 interactions 3.866E-4 3.132E-3 2.061E-2
1.566E-1
 2 77
Show 45 more annotations

10: Cytoband [Display Chart] 7 input genes in category / 7 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 3q26.2-q27 3q26.2-q27 4.039E-4 2.827E-3 7.330E-3 2.827E-3 1 2
2 20q12-q13.1 20q12-q13.1 2.018E-3 7.063E-3 1.831E-2 1.413E-2 1 10
3 1p31 1p31 4.837E-3 1.129E-2 2.927E-2 3.386E-2 1 24
4 1p35.3 1p35.3 6.847E-3 1.198E-2 3.107E-2 4.793E-2 1 34
5 6p21 6p21 1.226E-2 1.625E-2 4.212E-2
8.579E-2
 1 61
6 19q13.32 19q13.32 1.585E-2 1.625E-2 4.212E-2
1.109E-1
 1 79
7 12q24.31 12q24.31 1.625E-2 1.625E-2 4.212E-2
1.137E-1
 1 81
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 6 input genes in category / 127 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ACAWNRNSRCGG UNKNOWN ACAWNRNSRCGG UNKNOWN 4.434E-4 3.594E-2
1.950E-1
5.632E-2
 2 54
2 CCGNMNNTNACG UNKNOWN CCGNMNNTNACG UNKNOWN 5.660E-4 3.594E-2
1.950E-1
7.188E-2
 2 61

12: Gene Family [Display Chart] 7 input genes in category / 5 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 737 RNA binding motif containing|Serine and arginine rich splicing factors genenames.org 1.001E-15 5.005E-15 1.143E-14 5.005E-15 5 12
2 725 RNA binding motif containing genenames.org 1.664E-11 4.159E-11 9.497E-11 8.318E-11 6 213
3 1256 Basic leucine zipper proteins|Fos transcription factor family genenames.org 1.538E-3 2.564E-3 5.854E-3 7.691E-3 1 4
4 506 Basic leucine zipper proteins genenames.org 1.870E-2 2.338E-2
5.338E-2
9.352E-2
 1 49

13: Coexpression [Display Chart] 7 input genes in category / 797 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M2135 Cluster 1: genes with similar expression profiles across follicular thyrorid carcinoma (FTC) samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.509E-7 2.797E-4 2.030E-3 2.797E-4 3 51
2 M2879 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.585E-6 6.317E-4 4.585E-3 1.263E-3 4 342
3 M4539 Genes up-regulated in comparison of CD8 T cells with progressing HIV infection versus those with controlled HIV infection. MSigDB C7: Immunologic Signatures (v6.0) 2.139E-5 3.460E-3 2.512E-2 1.704E-2 3 199
4 M9901 Genes down-regulated in dendritic cells: untreated versus 2h after infection of Leishmania major. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 3.460E-3 2.512E-2 1.730E-2 3 200
5 M4473 Genes up-regulated in comparison of naive CD4 [GeneID=920] CD8 T cells versus unstimulated neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 3.460E-3 2.512E-2 1.730E-2 3 200
6 M904 Up-regulated genes that vary between HNSCC (head and neck squamous cell carcinoma) groups formed on the basis of their level of pathological differentiation: well vs poorly differentiated tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.558E-5 4.137E-3 3.003E-2 2.836E-2 3 236
7 14760100-Table1 Human Bone Shammas04 51genes GeneSigDB 3.633E-5 4.137E-3 3.003E-2 2.896E-2 2 31
8 M15123 Genes down-regulated in at least 8 of 11 sarcoma cell lines by trabectedin [PubChem=3199]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.372E-5 5.352E-3 3.885E-2 4.282E-2 3 271
9 19014521-TableS6a Human Breast Reyal08 41genes GeneSigDB 6.398E-5 5.666E-3 4.112E-2
5.099E-2
 2 41
10 M19610 Marker genes up-regulated in the 'unannotated' subclass of hepatocellular carcinoma (HCC) samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.768E-4 2.153E-2
1.563E-1
2.206E-1
 2 85
11 18535662-TableS1b Mouse Lymphoma Wu08 1114genes GeneSigDB 3.195E-4 2.153E-2
1.563E-1
2.547E-1
 3 495
12 15846300-SuppTable4 Human Stomach Hofsli05 99genes RegulatedbyPACAP GeneSigDB 3.242E-4 2.153E-2
1.563E-1
2.584E-1
 2 92
13 M12016 Genes up-regulated in epithelial ovarian cancer (EOC) biopsies: invasive (TOV) vs low malignant potential (LMP) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.237E-4 2.160E-2
1.568E-1
4.174E-1
 2 117
14 M12828 Genes up-regulated in reverted NIH3T3 cells (fibroblasts transformed by activated KRAS [GeneID=3845] which then reverted to normal cells upon stable over-expression of a dominant negative form of CDC25 [GeneID=5923]) vs normal fibroblasts. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.508E-4 2.160E-2
1.568E-1
4.390E-1
 2 120
15 15940270-Figure1D Human Ovarian Ouellet05 137genes GeneSigDB 6.459E-4 2.160E-2
1.568E-1
5.148E-1
 2 130
16 18006812-TableS2 Human Lymphoma Piccaluga07 214genes GeneSigDB 6.658E-4 2.160E-2
1.568E-1
5.306E-1
 2 132
17 M4781 Down-regulated genes in angioimmunoblastic lymphoma (AILT) compared to normal T lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.860E-4 2.160E-2
1.568E-1
5.467E-1
 2 134
18 M314 Up-regulated genes in lung tissue of smokers with chronic obstructive pulmonary disease (COPD) vs smokers without disease (GOLD-2 vs GOLD-0). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.396E-4 2.160E-2
1.568E-1
7.489E-1
 2 157
19 M8129 Genes down-regulated in AGS cells (gastric adenocarcinoma): control versus H. pylori LPS. MSigDB C7: Immunologic Signatures (v6.0) 9.999E-4 2.160E-2
1.568E-1
7.969E-1
 2 162
20 M6206 Genes differentially expressed in hereditary breast cancer tumors with mutated BRCA1 [GeneID=672] compared to those with mutated BRCA2 [GeneID=675]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.012E-3 2.160E-2
1.568E-1
8.067E-1
 2 163
21 M18811 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200] in a compendium of normal tissues. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.075E-3 2.160E-2
1.568E-1
8.565E-1
 2 168
22 M11585 Genes up-regulated in MCF7 cells (breast cancer) after stimulation with NRG1 [GeneID=3084]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.165E-3 2.160E-2
1.568E-1
9.286E-1
 2 175
23 M6564 Genes up-regulated in lesional skin biopsies from mycosis fundoides patients compared to the normal skin samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.192E-3 2.160E-2
1.568E-1
9.497E-1
 2 177
24 M7460 Genes down-regulated in CD4 [GeneID=920] T cells: medium versus TGF beta and IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.301E-3 2.160E-2
1.568E-1
1.000E0
 2 185
25 M7242 Genes up-regulated in thymus: whole cortex versus whole medulla. MSigDB C7: Immunologic Signatures (v6.0) 1.458E-3 2.160E-2
1.568E-1
1.000E0
 2 196
26 M7558 Genes up-regulated in CD11b+ cells from spleen of BALB/c mice: healthy versus bearing C26GM colon carcinoma. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.160E-2
1.568E-1
1.000E0
 2 199
27 M4846 Genes up-regulated in comparison of CD8 T cells versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.160E-2
1.568E-1
1.000E0
 2 199
28 M7835 Genes up-regulated in dendritic cells: plasmacytoid versus cultured common progenitors treated by TGFB1 [GeneID=7040] for 4h. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.160E-2
1.568E-1
1.000E0
 2 199
29 M3074 Genes down-regulated in comparison of memory CD8 T cells versus effector CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.160E-2
1.568E-1
1.000E0
 2 199
30 M3639 Genes up-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after stimulation with IL12. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.160E-2
1.568E-1
1.000E0
 2 199
31 M9621 Genes down-regulated in T reg: wildtype versus DNMT1 [GeneID=1786] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
32 M7505 Genes down-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper) from germinal center. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
33 M3997 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
34 M4386 Genes down-regulated in comparison of lung tissue from wild type mice subjected to ozone for 0 h versus that from TLR4 [GeneID=7099] deficient mice subjected to ozone for 48 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
35 M4465 Genes down-regulated in comparison of neutrophils versus dendritic cells (DC). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
36 M5811 Genes down-regulated in comparison of untreated macrophages from IRAK4 [GeneID=51135] deficient mice at 4 h versus those treated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
37 M6605 Genes down-regulated in bone marrow-derived macrophages: untreated (0 min) versus IL10 [GeneID=3586] and LPS (180 min). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
38 M3628 Genes down-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after treatment with trichostatin A (TSA) [PubChem=5562]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
39 M9907 Genes down-regulated in dendritic cells: untreated versus 4h after infection of Leishmania major. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
40 M4994 Genes down-regulated in comparison of monocytes from LAIV influenza vaccinee pre-vaccination versus those at day 7 post-vaccination MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
41 M5787 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from patients with type 1 diabetes at the time of the diagnosis versus those at 4 months later. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
42 M7134 Genes down-regulated in splenic dendritic cells from IFNB1 [GeneID=3456] knockout mice: CD8A+ [GeneID=925] versus CD8A- [GeneID=925] populations. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
43 M9734 Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
44 M4467 Genes down-regulated in comparison of neutrophils versusl monocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
45 M8851 Genes down-regulated in multipotent progenitors versus RAG2 [GeneID=5897] knockout NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
46 M4030 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
47 M5473 Genes down-regulated in comparison of dendritic cells (DC) versus basophils. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
48 M5926 A subgroup of genes regulated by MYC - version 1 (v1). MSigDB H: Hallmark Gene Sets (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
49 M10031 Genes up-regulated in NK cells versus B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
50 M4813 Genes up-regulated in comparison of B cells versus neutrophils. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.160E-2
1.568E-1
1.000E0
 2 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 7 input genes in category / 950 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK15 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK15 Adult, Development, and Cancer types 1.714E-7 1.026E-4 7.628E-4 1.628E-4 4 185
2 Mesangium (MG)/Mesangium (MG) a Mesangium (MG)/Mesangium (MG) a 2.160E-7 1.026E-4 7.628E-4 2.052E-4 4 196
3 gudmap developingGonad e18.5 epididymis 500 k4 DevelopingGonad e18.5 epididymis emap-13166 k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.135E-5 2.611E-3 1.941E-2 1.078E-2 3 152
4 gudmap developingGonad e12.5 ovary k3 500 DevelopingGonad e12.5 ovary emap-28876 k-means-cluster#3 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.349E-5 2.611E-3 1.941E-2 1.281E-2 3 161
5 gudmap developingGonad e16.5 epididymis 500 k2 DevelopingGonad e16.5 epididymis emap-29702 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.374E-5 2.611E-3 1.941E-2 1.305E-2 3 162
6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Tumour RCC Mast cell/Kidney Tumour RCC IN15 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Tumour RCC Mast cell/Kidney Tumour RCC IN15 Adult, Development, and Cancer types 1.822E-5 2.884E-3 2.144E-2 1.731E-2 3 178
7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter IN-U/Ureter Normal RCC IN-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter IN-U/Ureter Normal RCC IN-U Adult, Development, and Cancer types 2.356E-5 3.198E-3 2.377E-2 2.239E-2 3 194
8 gudmap developingGonad e18.5 ovary 1000 k2 DevelopingGonad e18.5 ovary emap-12283 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.986E-5 3.381E-3 2.514E-2 2.837E-2 3 210
9 Lungmap Mouse Lung PND1 Immune Subtype Lymphocytes-A Lungmap Mouse Lung PND1 Immune Subtype Lymphocytes-A Lungmap CCHMC 3.203E-5 3.381E-3 2.514E-2 3.043E-2 3 215
10 gudmap developingGonad P2 epididymis 1000 k3 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.962E-5 4.647E-3 3.455E-2 4.714E-2 3 249
11 gudmap developingGonad e12.5 epididymis k3 1000 DevelopingGonad e12.5 epididymis emap-29139 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.579E-5 4.647E-3 3.455E-2
5.300E-2
 3 259
12 gudmap developingGonad e14.5 epididymis 1000 k3 DevelopingGonad e14.5 epididymis emap-29141 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 6.740E-5 4.647E-3 3.455E-2
6.403E-2
 3 276
13 gudmap developingGonad e12.5 ovary k3 1000 DevelopingGonad e12.5 ovary emap-28876 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 6.813E-5 4.647E-3 3.455E-2
6.472E-2
 3 277
14 gudmap developingGonad e18.5 epididymis 1000 k3 DevelopingGonad e18.5 epididymis emap-13166 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 7.109E-5 4.647E-3 3.455E-2
6.754E-2
 3 281
15 gudmap developingGonad e16.5 epididymis 1000 k2 DevelopingGonad e16.5 epididymis emap-29702 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 7.337E-5 4.647E-3 3.455E-2
6.970E-2
 3 284
16 Human Cell Atlas Human Cell Atlas B cell B cell Subtype CD34+ pre-B cycling Top 200 Genes Human Cell Atlas Human Cell Atlas B cell B cell Subtype CD34+ pre-B cycling Top 200 Genes 8.981E-5 5.332E-3 3.964E-2
8.532E-2
 3 304
17 gudmap developingGonad e11.5 ovary + mesonephros k2 1000 DevelopingGonad e11.5 ovary + mesonephros emap-3226 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.075E-4 6.007E-3 4.466E-2
1.021E-1
 3 323
18 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal-Cortex Wilms Renal cell carcinoma/Kidney Normal-Cortex Wilms T17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal-Cortex Wilms Renal cell carcinoma/Kidney Normal-Cortex Wilms T17 Adult, Development, and Cancer types 1.816E-4 8.823E-3
6.559E-2
1.725E-1
 2 65
19 10X Human 68K PBMC CD4+/CD45RA+/CD25- Naive T Subtype CD4+/CD45RA+/CD25- Naive T-CD4+/CD45RA+/CD25- Naive T c6 Top 200 Genes 10X Human 68K PBMC CD4+/CD45RA+/CD25- Naive T Subtype CD4+/CD45RA+/CD25- Naive T-CD4+/CD45RA+/CD25- Naive T c6 Top 200 Genes 1.835E-4 8.823E-3
6.559E-2
1.744E-1
 3 387
20 gudmap developingGonad e18.5 epididymis 500 DevelopingGonad e18.5 epididymis emap-13166 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.099E-4 8.823E-3
6.559E-2
1.994E-1
 3 405
21 gudmap developingGonad e16.5 epididymis 500 DevelopingGonad e16.5 epididymis emap-29702 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.130E-4 8.823E-3
6.559E-2
2.023E-1
 3 407
22 gudmap developingGonad e12.5 ovary 500 DevelopingGonad e12.5 ovary emap-28876 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.161E-4 8.823E-3
6.559E-2
2.053E-1
 3 409
23 gudmap developingGonad e14.5 epididymis 500 DevelopingGonad e14.5 epididymis emap-29141 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.224E-4 8.823E-3
6.559E-2
2.113E-1
 3 413
24 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter Ureter others/Ureter Normal RCC Ureter others Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter Ureter others/Ureter Normal RCC Ureter others Adult, Development, and Cancer types 2.229E-4 8.823E-3
6.559E-2
2.118E-1
 2 72
25 gudmap developingGonad e16.5 epididymis 200 k4 DevelopingGonad e16.5 epididymis emap-29702 k-means-cluster#4 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 2.484E-4 8.971E-3
6.669E-2
2.360E-1
 2 76
26 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Polydendrocyte/Polydendrocyte/Polydendrocyte/Tnr//Tnr BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Polydendrocyte/Polydendrocyte/Polydendrocyte/Tnr//Tnr BrainMap 2.550E-4 8.971E-3
6.669E-2
2.422E-1
 2 77
27 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-G/Kidney Normal-Cortex Wilms EN-G/Kidney Normal-Cortex Wilms EN12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-G/Kidney Normal-Cortex Wilms EN-G/Kidney Normal-Cortex Wilms EN12 Adult, Development, and Cancer types 2.550E-4 8.971E-3
6.669E-2
2.422E-1
 2 77
28 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter others Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Ureter others Adult, Development, and Cancer types 3.207E-4 1.088E-2
8.088E-2
3.046E-1
 1 1
29 6mo cortical organoids wt 6mo cortical organoids wt Subtype 6 static Subtype 6 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype 6 static Subtype 6 Top 100 Genes 3.799E-4 1.245E-2
9.252E-2
3.609E-1
 2 94
30 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour VHL RCC R U/Kidney Tumour VHL RCC R7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour VHL RCC R U/Kidney Tumour VHL RCC R7 Adult, Development, and Cancer types 4.919E-4 1.558E-2
1.158E-1
4.673E-1
 2 107
31 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal VHL RCC Nephron epithelium/Kidney Normal VHL RCC N12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal VHL RCC Nephron epithelium/Kidney Normal VHL RCC N12 Adult, Development, and Cancer types 5.484E-4 1.657E-2
1.232E-1
5.210E-1
 2 113
32 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney B cell/Kidney Tumour Wilms B cell/Kidney Tumour Wilms IN13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney B cell/Kidney Tumour Wilms B cell/Kidney Tumour Wilms IN13 Adult, Development, and Cancer types 5.581E-4 1.657E-2
1.232E-1
5.302E-1
 2 114
33 gudmap developingKidney e15.5 Endothelial cells 100 k4 DevelopingKidney e15.5 Endothelial cells emap-29965 k-means-cluster#4 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 6.413E-4 1.846E-2
1.372E-1
6.092E-1
 1 2
34 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal VHL RCC NK cell/Kidney Normal VHL RCC NK18 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal VHL RCC NK cell/Kidney Normal VHL RCC NK18 Adult, Development, and Cancer types 6.811E-4 1.903E-2
1.415E-1
6.471E-1
 2 126
35 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Proliferating NK cell/Kidney Normal VHL RCC Proliferating NK cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Proliferating NK cell/Kidney Normal VHL RCC Proliferating NK cell Adult, Development, and Cancer types 7.928E-4 2.092E-2
1.555E-1
7.531E-1
 2 136
36 gudmap developingGonad P2 epididymis 500 k2 DevelopingGonad P2 epididymis emap-30199 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 7.928E-4 2.092E-2
1.555E-1
7.531E-1
 2 136
37 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R22 Adult, Development, and Cancer types 8.279E-4 2.126E-2
1.580E-1
7.865E-1
 2 139
38 gudmap developingKidney e15.5 Endothelial cells 200 k5 DevelopingKidney e15.5 Endothelial cells emap-29965 k-means-cluster#5 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 9.618E-4 2.219E-2
1.650E-1
9.137E-1
 1 3
39 gudmap developingGonad e12.5 epididymis k5 500 DevelopingGonad e12.5 epididymis emap-29139 k-means-cluster#5 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 9.630E-4 2.219E-2
1.650E-1
9.148E-1
 2 150
40 gudmap developingGonad P2 ovary 1000 k5 DevelopingGonad P2 ovary emap-30224 k-means-cluster#5 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 9.758E-4 2.219E-2
1.650E-1
9.270E-1
 2 151
41 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter NK cell/Ureter Normal RCC NK cell/Ureter Normal RCC NK8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter NK cell/Ureter Normal RCC NK cell/Ureter Normal RCC NK8 Adult, Development, and Cancer types 9.886E-4 2.219E-2
1.650E-1
9.392E-1
 2 152
42 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter R U/Ureter Normal RCC R U/Ureter Normal RCC R21 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter R U/Ureter Normal RCC R U/Ureter Normal RCC R21 Adult, Development, and Cancer types 1.068E-3 2.219E-2
1.650E-1
1.000E0
 2 158
43 gudmap developingGonad e16.5 epididymis 200 DevelopingGonad e16.5 epididymis emap-29702 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.177E-3 2.219E-2
1.650E-1
1.000E0
 2 166
44 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal-Medulla post-natal kidney Renal cell carcinoma/Kidney Normal-Medulla post-natal kidney T12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal-Medulla post-natal kidney Renal cell carcinoma/Kidney Normal-Medulla post-natal kidney T12 Adult, Development, and Cancer types 1.249E-3 2.219E-2
1.650E-1
1.000E0
 2 171
45 gudmap developingGonad e11.5 ovary + mesonephros k4 500 DevelopingGonad e11.5 ovary + mesonephros emap-3226 k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.263E-3 2.219E-2
1.650E-1
1.000E0
 2 172
46 gudmap developingKidney e11.5 ureteric bud 100 k2 DevelopingKidney e11.5 ureteric bud emap-3844 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.282E-3 2.219E-2
1.650E-1
1.000E0
 1 4
47 Sample Type by Project: Shred 1/TCGA-Liver/Hepatocellular Carcinoma/Hepatocellular Carcinoma/3/0 Sample Type by Project: Shred 1/TCGA-Liver/Hepatocellular Carcinoma/Hepatocellular Carcinoma/3/0 TCGA-Liver 1.282E-3 2.219E-2
1.650E-1
1.000E0
 1 4
48 gudmap developingGonad e14.5 epididymis 500 k4 DevelopingGonad e14.5 epididymis emap-29141 k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.307E-3 2.219E-2
1.650E-1
1.000E0
 2 175
49 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal VHL RCC U U/Kidney Normal VHL RCC U17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal VHL RCC U U/Kidney Normal VHL RCC U17 Adult, Development, and Cancer types 1.352E-3 2.219E-2
1.650E-1
1.000E0
 2 178
50 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal-Medulla Wilms Endothelium/Kidney Normal-Medulla Wilms N4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal-Medulla Wilms Endothelium/Kidney Normal-Medulla Wilms N4 Adult, Development, and Cancer types 1.382E-3 2.219E-2
1.650E-1
1.000E0
 2 180
Show 45 more annotations

15: Computational [Display Chart] 7 input genes in category / 88 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M8084 MODULE 183 RNA splicing. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.025E-10 1.782E-8 9.018E-8 1.782E-8 5 65
2 M15698 GCM APEX1 Neighborhood of APEX1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.382E-7 2.368E-5 1.198E-4 4.736E-5 4 114
3 M12309 GCM PPP1CC Neighborhood of PPP1CC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.668E-6 1.663E-4 8.413E-4 4.988E-4 3 56
4 M7466 MODULE 32 Genes in the cancer module 32. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.072E-5 2.359E-4 1.194E-3 9.435E-4 4 241
5 M1109 MORF UBE2N Neighborhood of UBE2N MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.710E-5 4.769E-4 2.413E-3 2.385E-3 3 94
6 M5178 GNF2 HDAC1 Neighborhood of HDAC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.342E-5 6.368E-4 3.222E-3 3.821E-3 3 110
7 M14843 MODULE 98 Genes in the cancer module 98. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.376E-5 9.273E-4 4.692E-3 6.491E-3 4 393
8 M19767 MORF G22P1 Neighborhood of G22P1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.617E-4 1.779E-3 9.002E-3 1.423E-2 3 171
9 M14651 GNF2 TDG Neighborhood of TDG MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.454E-4 1.867E-3 9.447E-3 2.159E-2 2 35
10 M4536 GNF2 G22P1 Neighborhood of G22P1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.597E-4 1.867E-3 9.447E-3 2.286E-2 2 36
11 M6582 GCM RAD21 Neighborhood of RAD21 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.745E-4 1.867E-3 9.447E-3 2.415E-2 2 37
12 M12593 GNF2 ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.745E-4 1.867E-3 9.447E-3 2.415E-2 2 37
13 M3292 GCM HDAC1 Neighborhood of HDAC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.896E-4 1.867E-3 9.447E-3 2.549E-2 2 38
14 M2705 MORF ACP1 Neighborhood of ACP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.970E-4 1.867E-3 9.447E-3 2.614E-2 3 210
15 M4591 GNF2 UBE2I Neighborhood of UBE2I MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.890E-4 2.238E-3 1.133E-2 3.423E-2 2 44
16 M16765 MODULE 332 Genes in the cancer module 332. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.069E-4 2.238E-3 1.133E-2 3.581E-2 2 45
17 M11080 MORF HDAC1 Neighborhood of HDAC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.199E-4 2.691E-3 1.362E-2 4.575E-2 3 254
18 M7191 MORF DEK Neighborhood of DEK MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.694E-4 2.784E-3 1.409E-2
5.011E-2
 3 262
19 M15612 GNF2 DEK Neighborhood of DEK MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.765E-4 3.133E-3 1.586E-2
5.953E-2
 2 58
20 M1646 GCM DDX5 Neighborhood of DDX5 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 8.493E-4 3.737E-3 1.891E-2
7.474E-2
 2 65
21 M19743 GCM CBFB Neighborhood of CBFB MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.844E-4 4.086E-3 2.067E-2
8.663E-2
 2 70
22 M4842 MODULE 83 Genes in the cancer module 83. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.021E-3 4.086E-3 2.067E-2
8.988E-2
 3 320
23 M14632 MORF PCNA Neighborhood of PCNA MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.381E-3 5.284E-3 2.674E-2
1.215E-1
 2 83
24 M12304 GCM PSME1 Neighborhood of PSME1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.448E-3 5.309E-3 2.687E-2
1.274E-1
 2 85
25 M8078 GNF2 APEX1 Neighborhood of APEX1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.694E-3 5.962E-3 3.017E-2
1.491E-1
 2 92
26 M9810 GCM CSNK2B Neighborhood of CSNK2B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.958E-3 6.628E-3 3.354E-2
1.723E-1
 2 99
27 M16184 MORF ERH Neighborhood of ERH MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.587E-3 8.433E-3 4.267E-2
2.277E-1
 2 114
28 M3928 GNF2 DAP3 Neighborhood of DAP3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.816E-3 8.829E-3 4.468E-2
2.478E-1
 2 119
29 M4246 MORF EIF3S6 Neighborhood of EIF3S6 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.909E-3 8.829E-3 4.468E-2
2.560E-1
 2 121
30 M16486 GCM ACTG1 Neighborhood of ACTG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.053E-3 8.956E-3 4.532E-2
2.687E-1
 2 124
31 M6545 MORF FBL Neighborhood of FBL MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.821E-3 1.085E-2
5.488E-2
3.362E-1
 2 139
32 M1339 GNF2 FBL Neighborhood of FBL MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.263E-3 1.172E-2
5.933E-2
3.752E-1
 2 147
33 M18610 MORF PPP1CC Neighborhood of PPP1CC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.280E-3 1.408E-2
7.125E-2
4.647E-1
 2 164
34 M7181 MORF PPP1CA Neighborhood of PPP1CA MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.599E-3 1.449E-2
7.333E-2
4.927E-1
 2 169
35 M19884 MORF ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.543E-3 1.897E-2
9.597E-2
6.638E-1
 2 197
36 M12287 MORF SKP1A Neighborhood of SKP1A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.919E-3 1.936E-2
9.795E-2
6.968E-1
 2 202
37 M18997 MORF XRCC5 Neighborhood of XRCC5 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.052E-2 2.502E-2
1.266E-1
9.258E-1
 2 234
38 M10939 MORF UBE2I Neighborhood of UBE2I MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.087E-2 2.517E-2
1.274E-1
9.565E-1
 2 238
39 M17615 MORF RAN Neighborhood of RAN MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.365E-2 3.080E-2
1.559E-1
1.000E0
 2 268
40 M13419 MORF BUB3 Neighborhood of BUB3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.444E-2 3.177E-2
1.608E-1
1.000E0
 2 276
41 M18002 MORF CSNK2B Neighborhood of CSNK2B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.556E-2 3.340E-2
1.690E-1
1.000E0
 2 287
42 M17658 MODULE 198 Genes in the cancer module 198. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.725E-2 3.531E-2
1.787E-1
1.000E0
 2 303
43 M18398 MORF GNB1 Neighborhood of GNB1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.725E-2 3.531E-2
1.787E-1
1.000E0
 2 303
44 M6308 GNF2 RPA1 Neighborhood of RPA1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.937E-2 3.874E-2
1.960E-1
1.000E0
 1 28
45 M3625 GCM TPR Neighborhood of TPR MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.211E-2 4.324E-2
2.188E-1
1.000E0
 1 32
46 M14741 GCM ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.485E-2 4.753E-2
2.405E-1
1.000E0
 1 36
Show 41 more annotations

16: MicroRNA [Display Chart] 7 input genes in category / 406 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ACATTCC,MIR-1:MSigDB ACATTCC,MIR-1:MSigDB MSigDB 7.995E-9 1.623E-6 1.069E-5 3.246E-6 4 283
2 ACATTCC,MIR-206:MSigDB ACATTCC,MIR-206:MSigDB MSigDB 7.995E-9 1.623E-6 1.069E-5 3.246E-6 4 283
3 hsa-miR-1:PITA hsa-miR-1:PITA TOP PITA 2.367E-8 1.942E-6 1.279E-5 9.608E-6 4 371
4 hsa-miR-206:PITA hsa-miR-206:PITA TOP PITA 2.367E-8 1.942E-6 1.279E-5 9.608E-6 4 371
5 hsa-miR-613:PITA hsa-miR-613:PITA TOP PITA 2.392E-8 1.942E-6 1.279E-5 9.712E-6 4 372
6 AACATTC,MIR-409-3P:MSigDB AACATTC,MIR-409-3P:MSigDB MSigDB 2.172E-7 1.470E-5 9.679E-5 8.819E-5 3 134
7 hsa-miR-376a-5p:Functional MTI Functional MTI miRTarbase 1.938E-5 1.124E-3 7.400E-3 7.866E-3 2 70
8 hsa-miR-542-5p:mirSVR highEffct hsa-miR-542-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.887E-5 1.452E-3 9.558E-3 1.578E-2 2 99
9 hsa-miR-4418:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.046E-5 1.452E-3 9.558E-3 1.643E-2 2 101
10 hsa-miR-509-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.208E-5 1.452E-3 9.558E-3 1.708E-2 2 103
11 GGTGTGT,MIR-329:MSigDB GGTGTGT,MIR-329:MSigDB MSigDB 4.208E-5 1.452E-3 9.558E-3 1.708E-2 2 103
12 hsa-miR-509-3-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.290E-5 1.452E-3 9.558E-3 1.742E-2 2 104
13 CAGCAGG,MIR-370:MSigDB CAGCAGG,MIR-370:MSigDB MSigDB 8.696E-5 2.590E-3 1.706E-2 3.530E-2 2 148
14 GTGACTT,MIR-224:MSigDB GTGACTT,MIR-224:MSigDB MSigDB 8.932E-5 2.590E-3 1.706E-2 3.627E-2 2 150
15 hsa-miR-370:PITA hsa-miR-370:PITA TOP PITA 1.202E-4 3.253E-3 2.142E-2 4.879E-2 2 174
16 hsa-miR-618:PITA hsa-miR-618:PITA TOP PITA 2.865E-4 6.311E-3 4.156E-2
1.163E-1
 2 269
17 TGCACTG,MIR-152:MSigDB TGCACTG,MIR-152:MSigDB MSigDB 3.305E-4 6.311E-3 4.156E-2
1.342E-1
 2 289
18 TGCACTG,MIR-148A:MSigDB TGCACTG,MIR-148A:MSigDB MSigDB 3.305E-4 6.311E-3 4.156E-2
1.342E-1
 2 289
19 TGCACTG,MIR-148B:MSigDB TGCACTG,MIR-148B:MSigDB MSigDB 3.305E-4 6.311E-3 4.156E-2
1.342E-1
 2 289
20 hsa-miR-509-5p:PITA hsa-miR-509-5p:PITA TOP PITA 3.420E-4 6.311E-3 4.156E-2
1.388E-1
 2 294
21 hsa-miR-509-3-5p:PITA hsa-miR-509-3-5p:PITA TOP PITA 3.420E-4 6.311E-3 4.156E-2
1.388E-1
 2 294
22 ATGTACA,MIR-493:MSigDB ATGTACA,MIR-493:MSigDB MSigDB 3.420E-4 6.311E-3 4.156E-2
1.388E-1
 2 294
23 hsa-miR-1208:PITA hsa-miR-1208:PITA TOP PITA 3.655E-4 6.387E-3 4.206E-2
1.484E-1
 2 304
24 hsa-miR-454*:mirSVR highEffct hsa-miR-454*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.776E-4 6.387E-3 4.206E-2
1.533E-1
 2 309
25 hsa-miR-193b:mirSVR highEffct hsa-miR-193b:mirSVR conserved highEffect-0.5 MicroRNA.org 6.979E-4 9.073E-3
5.974E-2
2.833E-1
 2 421
26 hsa-miR-1284:PITA hsa-miR-1284:PITA TOP PITA 7.177E-4 9.073E-3
5.974E-2
2.914E-1
 2 427
27 hsa-miR-105:PITA hsa-miR-105:PITA TOP PITA 7.379E-4 9.073E-3
5.974E-2
2.996E-1
 2 433
28 hsa-miR-544:PITA hsa-miR-544:PITA TOP PITA 7.686E-4 9.073E-3
5.974E-2
3.120E-1
 2 442
29 hsa-miR-4296:mirSVR highEffct hsa-miR-4296:mirSVR nonconserved highEffect-0.5 MicroRNA.org 7.720E-4 9.073E-3
5.974E-2
3.134E-1
 2 443
30 hsa-miR-486-5p:mirSVR highEffct hsa-miR-486-5p:mirSVR conserved highEffect-0.5 MicroRNA.org 7.859E-4 9.073E-3
5.974E-2
3.191E-1
 2 447
31 hsa-miR-4265:mirSVR highEffct hsa-miR-4265:mirSVR nonconserved highEffect-0.5 MicroRNA.org 7.894E-4 9.073E-3
5.974E-2
3.205E-1
 2 448
32 hsa-miR-452:PITA hsa-miR-452:PITA TOP PITA 7.999E-4 9.073E-3
5.974E-2
3.248E-1
 2 451
33 hsa-miR-802:PITA hsa-miR-802:PITA TOP PITA 8.034E-4 9.073E-3
5.974E-2
3.262E-1
 2 452
34 hsa-miR-1264:PITA hsa-miR-1264:PITA TOP PITA 8.070E-4 9.073E-3
5.974E-2
3.276E-1
 2 453
35 hsa-miR-4322:mirSVR highEffct hsa-miR-4322:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.680E-4 9.073E-3
5.974E-2
3.524E-1
 2 470
36 ACCAAAG,MIR-9:MSigDB ACCAAAG,MIR-9:MSigDB MSigDB 8.717E-4 9.073E-3
5.974E-2
3.539E-1
 2 471
37 hsa-miR-182:PITA hsa-miR-182:PITA TOP PITA 9.013E-4 9.073E-3
5.974E-2
3.659E-1
 2 479
38 hsa-miR-148a:PITA hsa-miR-148a:PITA TOP PITA 9.162E-4 9.073E-3
5.974E-2
3.720E-1
 2 483
39 hsa-miR-152:PITA hsa-miR-152:PITA TOP PITA 9.162E-4 9.073E-3
5.974E-2
3.720E-1
 2 483
40 hsa-miR-148b:PITA hsa-miR-148b:PITA TOP PITA 9.162E-4 9.073E-3
5.974E-2
3.720E-1
 2 483
41 hsa-miR-3165:mirSVR highEffct hsa-miR-3165:mirSVR nonconserved highEffect-0.5 MicroRNA.org 9.162E-4 9.073E-3
5.974E-2
3.720E-1
 2 483
42 hsa-miR-3147:mirSVR highEffct hsa-miR-3147:mirSVR nonconserved highEffect-0.5 MicroRNA.org 9.618E-4 9.298E-3
6.122E-2
3.905E-1
 2 495
43 hsa-miR-3178:mirSVR highEffct hsa-miR-3178:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.323E-3 2.194E-2
1.444E-1
9.433E-1
 1 24
44 hsa-miR-1238:PITA hsa-miR-1238:PITA TOP PITA 3.000E-3 2.768E-2
1.823E-1
1.000E0
 1 31
45 hsa-miR-520g-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.580E-3 3.041E-2
2.003E-1
1.000E0
 1 37
46 hsa-miR-4999-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.580E-3 3.041E-2
2.003E-1
1.000E0
 1 37
47 CTCTATG,MIR-368:MSigDB CTCTATG,MIR-368:MSigDB MSigDB 3.676E-3 3.041E-2
2.003E-1
1.000E0
 1 38
48 hsa-miR-5195-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.870E-3 3.041E-2
2.003E-1
1.000E0
 1 40
49 hsa-miR-6800-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.966E-3 3.041E-2
2.003E-1
1.000E0
 1 41
50 hsa-miR-3171:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.063E-3 3.041E-2
2.003E-1
1.000E0
 1 42
Show 45 more annotations

17: Drug [Display Chart] 7 input genes in category / 1022 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID005287709 AC1NRA5C Stitch 5.024E-10 5.134E-7 3.854E-6 5.134E-7 5 174
2 CID000010549 2-(ethylsulfonyl)ethanol Stitch 2.378E-7 1.215E-4 9.124E-4 2.431E-4 4 210
3 ctd:C578491 ((5Z)5-(1,3-benzodioxol-5-yl)methylene-2-phenylamino-3,5-dihydro-4H-imidazol-4-one) CTD 5.306E-6 1.807E-3 1.357E-2 5.422E-3 2 12
4 CID000092236 2-(2-naphthyloxy)propanoic acid Stitch 8.646E-5 2.209E-2
1.658E-1
8.836E-2
 2 47

18: Disease [Display Chart] 7 input genes in category / 99 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1841972 Glucocorticoid Receptor Deficiency DisGeNET Curated 2.264E-4 2.138E-2
1.107E-1
 2.242E-2 2 54
2 C3840252 Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma DisGeNET BeFree 4.320E-4 2.138E-2
1.107E-1
 4.276E-2 1 1
3 C0338451 Frontotemporal dementia DisGeNET Curated 1.534E-3 4.274E-2
2.213E-1
1.519E-1
 2 141
4 C0031887 Picornaviridae Infections DisGeNET BeFree 1.727E-3 4.274E-2
2.213E-1
1.710E-1
 1 4