|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
9405375
|
Three transitions in the RNA polymerase II transcription complex during initiation.
|
Pubmed
|
6.476E-11
|
1.405E-8
|
1.017E-7
|
5.058E-8
|
4
|
39
|
|
2
|
8946909
|
The general transcription factors of RNA polymerase II.
|
Pubmed
|
6.476E-11
|
1.405E-8
|
1.017E-7
|
5.058E-8
|
4
|
39
|
|
3
|
1939271
|
Abortive initiation is increased only for the weakest members of a set of down mutants of the adenovirus 2 major late promoter.
|
Pubmed
|
7.195E-11
|
1.405E-8
|
1.017E-7
|
5.619E-8
|
4
|
40
|
|
4
|
2449431
|
ATP activates transcription initiation from promoters by RNA polymerase II in a reversible step prior to RNA synthesis.
|
Pubmed
|
7.195E-11
|
1.405E-8
|
1.017E-7
|
5.619E-8
|
4
|
40
|
|
5
|
7729427
|
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.
|
Pubmed
|
2.110E-10
|
3.296E-8
|
2.386E-7
|
1.648E-7
|
3
|
7
|
|
6
|
9603525
|
Function of TAF(II)-containing complex without TBP in transcription by RNA polymerase II.
|
Pubmed
|
5.063E-10
|
6.591E-8
|
4.771E-7
|
3.955E-7
|
3
|
9
|
|
7
|
22323595
|
Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.
|
Pubmed
|
6.396E-10
|
7.137E-8
|
5.166E-7
|
4.996E-7
|
4
|
68
|
|
8
|
9153318
|
CCAAT binding NF-Y-TBP interactions: NF-YB and NF-YC require short domains adjacent to their histone fold motifs for association with TBP basic residues.
|
Pubmed
|
9.944E-10
|
9.708E-8
|
7.027E-7
|
7.766E-7
|
3
|
11
|
|
9
|
9311784
|
Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA.
|
Pubmed
|
1.723E-9
|
1.495E-7
|
1.082E-6
|
1.346E-6
|
3
|
13
|
|
10
|
14580349
|
The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis.
|
Pubmed
|
2.193E-9
|
1.713E-7
|
1.240E-6
|
1.713E-6
|
3
|
14
|
|
11
|
8764009
|
Mutations in the carboxy-terminal domain of TBP affect the synthesis of human immunodeficiency virus type 1 full-length and short transcripts similarly.
|
Pubmed
|
4.096E-9
|
2.285E-7
|
1.654E-6
|
3.199E-6
|
3
|
17
|
|
12
|
8121496
|
Direct interaction of human TFIID with the HIV-1 transactivator tat.
|
Pubmed
|
4.096E-9
|
2.285E-7
|
1.654E-6
|
3.199E-6
|
3
|
17
|
|
13
|
8680883
|
Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro.
|
Pubmed
|
4.096E-9
|
2.285E-7
|
1.654E-6
|
3.199E-6
|
3
|
17
|
|
14
|
7835343
|
Novel mechanism and factor for regulation by HIV-1 Tat.
|
Pubmed
|
4.096E-9
|
2.285E-7
|
1.654E-6
|
3.199E-6
|
3
|
17
|
|
15
|
29111974
|
Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.
|
Pubmed
|
4.914E-9
|
2.559E-7
|
1.852E-6
|
3.838E-6
|
3
|
18
|
|
16
|
7933101
|
Role of flanking E box motifs in human immunodeficiency virus type 1 TATA element function.
|
Pubmed
|
5.835E-9
|
2.822E-7
|
2.042E-6
|
4.557E-6
|
3
|
19
|
|
17
|
17884155
|
Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4.
|
Pubmed
|
6.864E-9
|
2.822E-7
|
2.042E-6
|
5.361E-6
|
3
|
20
|
|
18
|
17967894
|
STAGA recruits Mediator to the MYC oncoprotein to stimulate transcription and cell proliferation.
|
Pubmed
|
6.864E-9
|
2.822E-7
|
2.042E-6
|
5.361E-6
|
3
|
20
|
|
19
|
8764062
|
Interaction of human immunodeficiency virus type 1 Tat with a unique site of TFIID inhibits negative cofactor Dr1 and stabilizes the TFIID-TFIIA complex.
|
Pubmed
|
6.864E-9
|
2.822E-7
|
2.042E-6
|
5.361E-6
|
3
|
20
|
|
20
|
19240132
|
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function.
|
Pubmed
|
1.384E-8
|
5.405E-7
|
3.913E-6
|
1.081E-5
|
3
|
25
|
|
21
|
10591645
|
Three-dimensional structures of the TAFII-containing complexes TFIID and TFTC.
|
Pubmed
|
3.839E-8
|
1.428E-6
|
1.033E-5
|
2.998E-5
|
2
|
2
|
|
22
|
18722179
|
Dominant and redundant functions of TFIID involved in the regulation of hepatic genes.
|
Pubmed
|
5.071E-8
|
1.800E-6
|
1.303E-5
|
3.960E-5
|
3
|
38
|
|
23
|
28893950
|
The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.
|
Pubmed
|
5.493E-8
|
1.865E-6
|
1.350E-5
|
4.290E-5
|
3
|
39
|
|
24
|
9054383
|
Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes.
|
Pubmed
|
5.937E-8
|
1.932E-6
|
1.399E-5
|
4.637E-5
|
3
|
40
|
|
25
|
8849451
|
Tat-SF1: cofactor for stimulation of transcriptional elongation by HIV-1 Tat.
|
Pubmed
|
1.039E-7
|
3.245E-6
|
2.349E-5
|
8.111E-5
|
3
|
48
|
|
26
|
8504927
|
Multiple functional domains of human transcription factor IIB: distinct interactions with two general transcription factors and RNA polymerase II.
|
Pubmed
|
1.152E-7
|
3.331E-6
|
2.411E-5
|
8.994E-5
|
2
|
3
|
|
27
|
10409662
|
The cyclic AMP response element modulator family regulates the insulin gene transcription by interacting with transcription factor IID.
|
Pubmed
|
1.152E-7
|
3.331E-6
|
2.411E-5
|
8.994E-5
|
2
|
3
|
|
28
|
19635797
|
TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes.
|
Pubmed
|
2.303E-7
|
5.995E-6
|
4.340E-5
|
1.799E-4
|
2
|
4
|
|
29
|
8670810
|
Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.
|
Pubmed
|
2.303E-7
|
5.995E-6
|
4.340E-5
|
1.799E-4
|
2
|
4
|
|
30
|
9238003
|
Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF.
|
Pubmed
|
2.303E-7
|
5.995E-6
|
4.340E-5
|
1.799E-4
|
2
|
4
|
|
31
|
21729782
|
Human mediator subunit MED26 functions as a docking site for transcription elongation factors.
|
Pubmed
|
3.726E-7
|
7.888E-6
|
5.710E-5
|
2.910E-4
|
3
|
73
|
|
32
|
11959914
|
Isoform-specific interaction of HP1 with human TAFII130.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
33
|
9089417
|
Transcriptional activation domain of human BTEB2, a GC box-binding factor.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
34
|
9584164
|
Involvement of TFIID and USA components in transcriptional activation of the human immunodeficiency virus promoter by NF-kappaB and Sp1.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
35
|
9677423
|
Analysis of the role of TFIIE in transcriptional regulation through structure-function studies of the TFIIEbeta subunit.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
36
|
9841876
|
Oestrogen receptor facilitates the formation of preinitiation complex assembly: involvement of the general transcription factor TFIIB.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
37
|
9295363
|
Characterization of human activating transcription factor 4, a transcriptional activator that interacts with multiple domains of cAMP-responsive element-binding protein (CREB)-binding protein.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
38
|
8577725
|
Protein-protein interactions in eukaryotic transcription initiation: structure of the preinitiation complex.
|
Pubmed
|
3.838E-7
|
7.888E-6
|
5.710E-5
|
2.997E-4
|
2
|
5
|
|
39
|
8858156
|
Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130.
|
Pubmed
|
5.756E-7
|
1.096E-5
|
7.937E-5
|
4.496E-4
|
2
|
6
|
|
40
|
8794892
|
Trans-activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins: direct interactions with basal transcription factors.
|
Pubmed
|
5.756E-7
|
1.096E-5
|
7.937E-5
|
4.496E-4
|
2
|
6
|
|
41
|
24289924
|
Phosphorylation of p53 by TAF1 inactivates p53-dependent transcription in the DNA damage response.
|
Pubmed
|
5.756E-7
|
1.096E-5
|
7.937E-5
|
4.496E-4
|
2
|
6
|
|
42
|
17643375
|
Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.
|
Pubmed
|
7.256E-7
|
1.349E-5
|
9.766E-5
|
5.667E-4
|
4
|
390
|
|
43
|
15641800
|
Induced alpha-helix structure in the aryl hydrocarbon receptor transactivation domain modulates protein-protein interactions.
|
Pubmed
|
8.058E-7
|
1.464E-5
|
1.059E-4
|
6.293E-4
|
2
|
7
|
|
44
|
12665565
|
The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.
|
Pubmed
|
1.074E-6
|
1.864E-5
|
1.350E-4
|
8.390E-4
|
2
|
8
|
|
45
|
9045704
|
Specific interactions and potential functions of human TAFII100.
|
Pubmed
|
1.074E-6
|
1.864E-5
|
1.350E-4
|
8.390E-4
|
2
|
8
|
|
46
|
7926747
|
Transcription factor IIE binds preferentially to RNA polymerase IIa and recruits TFIIH: a model for promoter clearance.
|
Pubmed
|
1.381E-6
|
2.295E-5
|
1.661E-4
|
1.079E-3
|
2
|
9
|
|
47
|
14612417
|
The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.
|
Pubmed
|
1.381E-6
|
2.295E-5
|
1.661E-4
|
1.079E-3
|
2
|
9
|
|
48
|
20850016
|
Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.
|
Pubmed
|
1.848E-6
|
3.007E-5
|
2.177E-4
|
1.444E-3
|
3
|
124
|
|
49
|
11113176
|
Studies of nematode TFIIE function reveal a link between Ser-5 phosphorylation of RNA polymerase II and the transition from transcription initiation to elongation.
|
Pubmed
|
2.110E-6
|
3.362E-5
|
2.434E-4
|
1.648E-3
|
2
|
11
|
|
50
|
10373431
|
Identification of TATA-binding protein-free TAFII-containing complex subunits suggests a role in nucleosome acetylation and signal transduction.
|
Pubmed
|
2.531E-6
|
3.730E-5
|
2.700E-4
|
1.977E-3
|
2
|
12
|