Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc224_9, positive side

Go To Start Page
Input Parameters [Show Detail]
Training Results [Expand All] [Download All] [Sparse Matrix]
Display pValues and Scores as Table row limit

1: GO: Molecular Function [Display Chart] 9 input genes in category / 68 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005125 cytokine activity 1.323E-4 7.839E-3 3.766E-2 8.999E-3 3 222
2 GO:0008009 chemokine activity 2.306E-4 7.839E-3 3.766E-2 1.568E-2 2 48
3 GO:0042379 chemokine receptor binding 3.607E-4 8.176E-3 3.928E-2 2.453E-2 2 60
4 GO:0004906 interferon-gamma receptor activity 9.644E-4 1.639E-2
7.876E-2
6.558E-2
 1 2
5 GO:0004517 nitric-oxide synthase activity 1.446E-3 1.967E-2
9.449E-2
9.834E-2
 1 3
6 GO:0034617 tetrahydrobiopterin binding 1.928E-3 2.048E-2
9.839E-2
1.311E-1
 1 4
7 GO:0004904 interferon receptor activity 2.409E-3 2.048E-2
9.839E-2
1.638E-1
 1 5
8 GO:0031727 CCR2 chemokine receptor binding 2.409E-3 2.048E-2
9.839E-2
1.638E-1
 1 5
9 GO:0034618 arginine binding 3.372E-3 2.382E-2
1.144E-1
2.293E-1
 1 7
10 GO:0005516 calmodulin binding 3.542E-3 2.382E-2
1.144E-1
2.408E-1
 2 190
11 GO:0008603 cAMP-dependent protein kinase regulator activity 3.853E-3 2.382E-2
1.144E-1
2.620E-1
 1 8
12 GO:0043495 protein membrane anchor 4.333E-3 2.455E-2
1.180E-1
2.947E-1
 1 9
13 GO:0030898 actin-dependent ATPase activity 6.254E-3 3.268E-2
1.570E-1
4.252E-1
 1 13
14 GO:0010181 FMN binding 7.213E-3 3.268E-2
1.570E-1
4.905E-1
 1 15
15 GO:0001664 G protein-coupled receptor binding 7.327E-3 3.268E-2
1.570E-1
4.982E-1
 2 276
16 GO:0005126 cytokine receptor binding 8.008E-3 3.268E-2
1.570E-1
5.446E-1
 2 289
17 GO:0045236 CXCR chemokine receptor binding 8.171E-3 3.268E-2
1.570E-1
5.556E-1
 1 17
18 GO:0050998 nitric-oxide synthase binding 1.056E-2 3.951E-2
1.898E-1
7.183E-1
 1 22
19 GO:0000146 microfilament motor activity 1.104E-2 3.951E-2
1.898E-1
7.508E-1
 1 23
20 GO:0022829 wide pore channel activity 1.200E-2 4.078E-2
1.959E-1
8.157E-1
 1 25
21 GO:0045296 cadherin binding 1.533E-2 4.460E-2
2.142E-1
1.000E0
 1 32
22 GO:0043236 laminin binding 1.533E-2 4.460E-2
2.142E-1
1.000E0
 1 32
23 GO:0003779 actin binding 1.580E-2 4.460E-2
2.142E-1
1.000E0
 2 412
24 GO:0001968 fibronectin binding 1.581E-2 4.460E-2
2.142E-1
1.000E0
 1 33
25 GO:0043394 proteoglycan binding 1.676E-2 4.460E-2
2.142E-1
1.000E0
 1 35
26 GO:0051879 Hsp90 protein binding 1.723E-2 4.460E-2
2.142E-1
1.000E0
 1 36
27 GO:0048020 CCR chemokine receptor binding 1.771E-2 4.460E-2
2.142E-1
1.000E0
 1 37
28 GO:0043531 ADP binding 1.961E-2 4.708E-2
2.262E-1
1.000E0
 1 41
29 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen 2.008E-2 4.708E-2
2.262E-1
1.000E0
 1 42
Show 24 more annotations

2: GO: Biological Process [Display Chart] 9 input genes in category / 593 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001909 leukocyte mediated cytotoxicity 1.347E-5 6.680E-3 4.651E-2 7.989E-3 3 103
2 GO:0001906 cell killing 2.965E-5 6.680E-3 4.651E-2 1.758E-2 3 134
3 GO:0071346 cellular response to interferon-gamma 3.379E-5 6.680E-3 4.651E-2 2.004E-2 3 140
4 GO:0034341 response to interferon-gamma 5.320E-5 7.663E-3
5.336E-2
 3.155E-2 3 163
5 GO:0002703 regulation of leukocyte mediated immunity 7.629E-5 7.663E-3
5.336E-2
 4.524E-2 3 184
6 GO:0002699 positive regulation of immune effector process 7.753E-5 7.663E-3
5.336E-2
 4.598E-2 3 185
7 GO:0006909 phagocytosis 2.005E-4 1.400E-2
9.751E-2
1.189E-1
 3 255
8 GO:0071622 regulation of granulocyte chemotaxis 2.033E-4 1.400E-2
9.751E-2
1.206E-1
 2 45
9 GO:0001912 positive regulation of leukocyte mediated cytotoxicity 2.125E-4 1.400E-2
9.751E-2
1.260E-1
 2 46
10 GO:0031343 positive regulation of cell killing 2.825E-4 1.675E-2
1.166E-1
1.675E-1
 2 53
11 GO:0032103 positive regulation of response to external stimulus 4.203E-4 1.736E-2
1.209E-1
2.492E-1
 3 328
12 GO:0001910 regulation of leukocyte mediated cytotoxicity 4.516E-4 1.736E-2
1.209E-1
2.678E-1
 2 67
13 GO:0050727 regulation of inflammatory response 4.710E-4 1.736E-2
1.209E-1
2.793E-1
 3 341
14 GO:0032496 response to lipopolysaccharide 4.750E-4 1.736E-2
1.209E-1
2.817E-1
 3 342
15 GO:0033552 response to vitamin B3 4.833E-4 1.736E-2
1.209E-1
2.866E-1
 1 1
16 GO:0002443 leukocyte mediated immunity 5.341E-4 1.736E-2
1.209E-1
3.167E-1
 3 356
17 GO:0002237 response to molecule of bacterial origin 5.430E-4 1.736E-2
1.209E-1
3.220E-1
 3 358
18 GO:0035690 cellular response to drug 6.117E-4 1.736E-2
1.209E-1
3.627E-1
 2 78
19 GO:0031341 regulation of cell killing 6.434E-4 1.736E-2
1.209E-1
3.815E-1
 2 80
20 GO:0070098 chemokine-mediated signaling pathway 6.434E-4 1.736E-2
1.209E-1
3.815E-1
 2 80
21 GO:0050900 leukocyte migration 6.763E-4 1.736E-2
1.209E-1
4.011E-1
 3 386
22 GO:0002690 positive regulation of leukocyte chemotaxis 7.430E-4 1.736E-2
1.209E-1
4.406E-1
 2 86
23 GO:0030593 neutrophil chemotaxis 8.497E-4 1.736E-2
1.209E-1
5.039E-1
 2 92
24 GO:0009615 response to virus 9.133E-4 1.736E-2
1.209E-1
5.416E-1
 3 428
25 GO:1903923 positive regulation of protein processing in phagocytic vesicle 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
26 GO:0032796 uropod organization 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
27 GO:1903921 regulation of protein processing in phagocytic vesicle 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
28 GO:0034769 basement membrane disassembly 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
29 GO:1903919 negative regulation of actin filament severing 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
30 GO:0002357 defense response to tumor cell 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
31 GO:1900756 protein processing in phagocytic vesicle 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
32 GO:1903918 regulation of actin filament severing 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
33 GO:0071403 cellular response to high density lipoprotein particle stimulus 9.663E-4 1.736E-2
1.209E-1
5.730E-1
 1 2
34 GO:1990266 neutrophil migration 1.063E-3 1.844E-2
1.284E-1
6.306E-1
 2 103
35 GO:0002705 positive regulation of leukocyte mediated immunity 1.126E-3 1.844E-2
1.284E-1
6.675E-1
 2 106
36 GO:0002688 regulation of leukocyte chemotaxis 1.147E-3 1.844E-2
1.284E-1
6.800E-1
 2 107
37 GO:0002697 regulation of immune effector process 1.169E-3 1.844E-2
1.284E-1
6.930E-1
 3 466
38 GO:0071621 granulocyte chemotaxis 1.211E-3 1.844E-2
1.284E-1
7.184E-1
 2 110
39 GO:1903034 regulation of response to wounding 1.213E-3 1.844E-2
1.284E-1
7.191E-1
 3 472
40 GO:0035684 helper T cell extravasation 1.449E-3 1.907E-2
1.328E-1
8.594E-1
 1 3
41 GO:0090264 regulation of immune complex clearance by monocytes and macrophages 1.449E-3 1.907E-2
1.328E-1
8.594E-1
 1 3
42 GO:2000502 negative regulation of natural killer cell chemotaxis 1.449E-3 1.907E-2
1.328E-1
8.594E-1
 1 3
43 GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages 1.449E-3 1.907E-2
1.328E-1
8.594E-1
 1 3
44 GO:0002436 immune complex clearance by monocytes and macrophages 1.449E-3 1.907E-2
1.328E-1
8.594E-1
 1 3
45 GO:0002432 granuloma formation 1.449E-3 1.907E-2
1.328E-1
8.594E-1
 1 3
46 GO:0032963 collagen metabolic process 1.487E-3 1.907E-2
1.328E-1
8.818E-1
 2 122
47 GO:0097530 granulocyte migration 1.511E-3 1.907E-2
1.328E-1
8.961E-1
 2 123
48 GO:0002687 positive regulation of leukocyte migration 1.660E-3 2.040E-2
1.421E-1
9.846E-1
 2 129
49 GO:0050921 positive regulation of chemotaxis 1.686E-3 2.040E-2
1.421E-1
9.997E-1
 2 130
50 GO:0050729 positive regulation of inflammatory response 1.737E-3 2.061E-2
1.435E-1
1.000E0
 2 132
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 9 input genes in category / 64 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0031904 endosome lumen 6.403E-5 4.098E-3 1.944E-2 4.098E-3 2 26
2 GO:0030863 cortical cytoskeleton 9.015E-4 1.677E-2
7.957E-2
5.770E-2
 2 97
3 GO:0005775 vacuolar lumen 1.285E-3 1.677E-2
7.957E-2
8.227E-2
 2 116
4 GO:0097513 myosin II filament 1.416E-3 1.677E-2
7.957E-2
9.062E-2
 1 3
5 GO:0044448 cell cortex part 1.812E-3 1.677E-2
7.957E-2
1.160E-1
 2 138
6 GO:0036021 endolysosome lumen 1.887E-3 1.677E-2
7.957E-2
1.208E-1
 1 4
7 GO:0044194 cytolytic granule 1.887E-3 1.677E-2
7.957E-2
1.208E-1
 1 4
8 GO:0044299 C-fiber 2.359E-3 1.677E-2
7.957E-2
1.510E-1
 1 5
9 GO:0033093 Weibel-Palade body 2.359E-3 1.677E-2
7.957E-2
1.510E-1
 1 5
10 GO:0005826 actomyosin contractile ring 2.830E-3 1.811E-2
8.592E-2
1.811E-1
 1 6
11 GO:0001931 uropod 5.653E-3 2.783E-2
1.320E-1
3.618E-1
 1 12
12 GO:0070938 contractile ring 5.653E-3 2.783E-2
1.320E-1
3.618E-1
 1 12
13 GO:0031254 cell trailing edge 5.653E-3 2.783E-2
1.320E-1
3.618E-1
 1 12
14 GO:0005938 cell cortex 6.547E-3 2.993E-2
1.420E-1
4.190E-1
 2 266
15 GO:0036019 endolysosome 8.000E-3 3.413E-2
1.619E-1
5.120E-1
 1 17
16 GO:0099568 cytoplasmic region 9.640E-3 3.856E-2
1.829E-1
6.169E-1
 2 325
17 GO:0032982 myosin filament 1.081E-2 4.070E-2
1.931E-1
6.918E-1
 1 23
18 GO:0016460 myosin II complex 1.268E-2 4.505E-2
2.137E-1
8.115E-1
 1 27
19 GO:0008305 integrin complex 1.408E-2 4.505E-2
2.137E-1
9.011E-1
 1 30
20 GO:0098636 protein complex involved in cell adhesion 1.408E-2 4.505E-2
2.137E-1
9.011E-1
 1 30
21 GO:0008180 COP9 signalosome 1.594E-2 4.661E-2
2.211E-1
1.000E0
 1 34
22 GO:0001772 immunological synapse 1.641E-2 4.661E-2
2.211E-1
1.000E0
 1 35
23 GO:0044440 endosomal part 1.675E-2 4.661E-2
2.211E-1
1.000E0
 2 434
Show 18 more annotations

4: Human Phenotype [Display Chart] 6 input genes in category / 559 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0011900 Hypofibrinogenemia 3.779E-5 8.285E-3
5.720E-2
 2.113E-2 2 8
2 HP:0012156 Hemophagocytosis 4.856E-5 8.285E-3
5.720E-2
 2.715E-2 2 9
3 HP:0012229 CSF pleocytosis 4.856E-5 8.285E-3
5.720E-2
 2.715E-2 2 9
4 HP:0011898 Abnormality of circulating fibrinogen 6.067E-5 8.285E-3
5.720E-2
 3.391E-2 2 10
5 HP:0003362 Increased VLDL cholesterol concentration 7.411E-5 8.285E-3
5.720E-2
 4.143E-2 2 11
6 HP:0003233 Decreased HDL cholesterol concentration 2.814E-4 1.855E-2
1.281E-1
1.573E-1
 2 21
7 HP:0003075 Hypoproteinemia 2.814E-4 1.855E-2
1.281E-1
1.573E-1
 2 21
8 HP:0003141 Increased LDL cholesterol concentration 3.093E-4 1.855E-2
1.281E-1
1.729E-1
 2 22
9 HP:0002382 Variable mental retardation 3.963E-4 1.855E-2
1.281E-1
2.215E-1
 3 131
10 HP:0002383 Encephalitis 3.963E-4 1.855E-2
1.281E-1
2.215E-1
 3 131
11 HP:0003073 Hypoalbuminemia 4.428E-4 1.855E-2
1.281E-1
2.475E-1
 3 136
12 HP:0012116 Abnormal albumin level 4.428E-4 1.855E-2
1.281E-1
2.475E-1
 3 136
13 HP:0002155 Hypertriglyceridemia 5.030E-4 1.855E-2
1.281E-1
2.812E-1
 3 142
14 HP:0008151 Prolonged prothrombin time 5.044E-4 1.855E-2
1.281E-1
2.820E-1
 2 28
15 HP:0010990 Abnormality of the common coagulation pathway 5.415E-4 1.855E-2
1.281E-1
3.027E-1
 2 29
16 HP:0001325 Hypoglycemic coma 5.459E-4 1.855E-2
1.281E-1
3.052E-1
 3 146
17 HP:0012200 Abnormality of prothrombin 6.195E-4 1.855E-2
1.281E-1
3.463E-1
 2 31
18 HP:0002922 Increased CSF protein 7.026E-4 1.855E-2
1.281E-1
3.928E-1
 2 33
19 HP:0025456 Abnormal CSF protein level 7.026E-4 1.855E-2
1.281E-1
3.928E-1
 2 33
20 HP:0003281 Increased serum ferritin 7.461E-4 1.855E-2
1.281E-1
4.171E-1
 2 34
21 HP:0040133 Abnormal serum ferritin 7.461E-4 1.855E-2
1.281E-1
4.171E-1
 2 34
22 HP:0002445 Tetraplegia 7.461E-4 1.855E-2
1.281E-1
4.171E-1
 2 34
23 HP:0010980 Hyperlipoproteinemia 7.909E-4 1.855E-2
1.281E-1
4.421E-1
 2 35
24 HP:0003256 Abnormality of the coagulation cascade 7.966E-4 1.855E-2
1.281E-1
4.453E-1
 3 166
25 HP:0007430 Generalized edema 8.842E-4 1.977E-2
1.365E-1
4.943E-1
 2 37
26 HP:0002729 Follicular hyperplasia 9.827E-4 2.064E-2
1.425E-1
5.493E-1
 2 39
27 HP:0003645 Prolonged partial thromboplastin time 1.034E-3 2.064E-2
1.425E-1
5.779E-1
 2 40
28 HP:0011031 Abnormality of iron homeostasis 1.034E-3 2.064E-2
1.425E-1
5.779E-1
 2 40
29 HP:0001913 Granulocytopenia 1.129E-3 2.177E-2
1.503E-1
6.314E-1
 3 187
30 HP:0040235 Leukocyte inclusion bodies 1.275E-3 2.299E-2
1.587E-1
7.126E-1
 1 1
31 HP:0008264 Neutrophil inclusion bodies 1.275E-3 2.299E-2
1.587E-1
7.126E-1
 1 1
32 HP:0003077 Hyperlipidemia 1.456E-3 2.544E-2
1.756E-1
8.140E-1
 3 204
33 HP:0001911 Abnormal granulocyte morphology 1.548E-3 2.550E-2
1.760E-1
8.656E-1
 4 497
34 HP:0011030 Abnormality of transition element cation homeostasis 1.551E-3 2.550E-2
1.760E-1
8.669E-1
 2 49
35 HP:0001433 Hepatosplenomegaly 1.838E-3 2.936E-2
2.027E-1
1.000E0
 3 221
36 HP:0005517 T-cell lymphoma/leukemia 2.169E-3 3.367E-2
2.325E-1
1.000E0
 2 58
37 HP:0012190 T-cell lymphoma 2.243E-3 3.389E-2
2.340E-1
1.000E0
 2 59
38 HP:0001287 Meningitis 2.363E-3 3.476E-2
2.400E-1
1.000E0
 3 241
39 HP:0011450 Unusual CNS infection 2.909E-3 4.153E-2
2.867E-1
1.000E0
 3 259
40 HP:0012539 Non-Hodgkin lymphoma 2.972E-3 4.153E-2
2.867E-1
1.000E0
 2 68
41 HP:0001259 Coma 3.074E-3 4.191E-2
2.894E-1
1.000E0
 3 264
42 HP:0002716 Lymphadenopathy 3.493E-3 4.650E-2
3.210E-1
1.000E0
 3 276
43 HP:0030182 Tetraplegia/tetraparesis 3.701E-3 4.811E-2
3.322E-1
1.000E0
 2 76
44 HP:0002733 Abnormality of the lymph nodes 3.792E-3 4.818E-2
3.326E-1
1.000E0
 3 284
Show 39 more annotations

5: Mouse Phenotype [Display Chart] 6 input genes in category / 650 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0004392 abnormal CD8-positive, alpha-beta T cell physiology 2.205E-7 1.433E-4 1.011E-3 1.433E-4 4 116
2 MP:0004804 decreased susceptibility to autoimmune diabetes 1.626E-6 5.284E-4 3.728E-3 1.057E-3 3 46
3 MP:0001869 pancreas inflammation 7.782E-6 1.586E-3 1.119E-2 5.058E-3 3 77
4 MP:0005078 abnormal cytotoxic T cell physiology 9.761E-6 1.586E-3 1.119E-2 6.345E-3 3 83
5 MP:0002425 altered susceptibility to autoimmune disorder 1.533E-5 1.993E-3 1.406E-2 9.966E-3 4 335
6 MP:0005065 abnormal neutrophil morphology 3.124E-5 2.410E-3 1.700E-2 2.031E-2 4 401
7 MP:0005464 abnormal platelet physiology 3.508E-5 2.410E-3 1.700E-2 2.280E-2 3 127
8 MP:0001844 autoimmune response 3.716E-5 2.410E-3 1.700E-2 2.415E-2 4 419
9 MP:0005005 abnormal self tolerance 3.786E-5 2.410E-3 1.700E-2 2.461E-2 4 421
10 MP:0002339 abnormal lymph node morphology 4.041E-5 2.410E-3 1.700E-2 2.627E-2 4 428
11 MP:0005000 abnormal immune tolerance 4.078E-5 2.410E-3 1.700E-2 2.651E-2 4 429
12 MP:0005425 increased macrophage cell number 1.114E-4 5.641E-3 3.980E-2
7.239E-2
 3 187
13 MP:0002453 abnormal B lymphocyte antigen presentation 1.128E-4 5.641E-3 3.980E-2
7.333E-2
 2 29
14 MP:0005351 decreased susceptibility to autoimmune disorder 1.401E-4 6.351E-3 4.481E-2
9.105E-2
 3 202
15 MP:0004031 insulitis 1.466E-4 6.351E-3 4.481E-2
9.527E-2
 2 33
16 MP:0003179 thrombocytopenia 1.805E-4 7.061E-3 4.982E-2
1.173E-1
 3 220
17 MP:0006058 decreased cerebral infarction size 1.847E-4 7.061E-3 4.982E-2
1.200E-1
 2 37
18 MP:0006059 decreased susceptibility to ischemic brain injury 2.740E-4 9.654E-3
6.811E-2
1.781E-1
 2 45
19 MP:0005079 decreased cytotoxic T cell cytolysis 2.990E-4 9.654E-3
6.811E-2
1.943E-1
 2 47
20 MP:0002412 increased susceptibility to bacterial infection 3.027E-4 9.654E-3
6.811E-2
1.967E-1
 3 262
21 MP:0013280 abnormal cytotoxic T cell cytolysis 3.119E-4 9.654E-3
6.811E-2
2.027E-1
 2 48
22 MP:0002551 abnormal blood coagulation 3.721E-4 1.066E-2
7.518E-2
2.419E-1
 3 281
23 MP:0009676 abnormal hemostasis 3.800E-4 1.066E-2
7.518E-2
2.470E-1
 3 283
24 MP:0020202 abnormal macrophage cell number 4.042E-4 1.066E-2
7.518E-2
2.628E-1
 3 289
25 MP:0010308 decreased tumor latency 4.099E-4 1.066E-2
7.518E-2
2.664E-1
 2 55
26 MP:0011898 abnormal platelet cell number 4.424E-4 1.106E-2
7.804E-2
2.876E-1
 3 298
27 MP:0004003 abnormal vascular endothelial cell physiology 4.879E-4 1.175E-2
8.287E-2
3.171E-1
 2 60
28 MP:0002693 abnormal pancreas physiology 5.209E-4 1.206E-2
8.506E-2
3.386E-1
 3 315
29 MP:0002343 abnormal lymph node cortex morphology 5.379E-4 1.206E-2
8.506E-2
3.497E-1
 2 63
30 MP:0013717 hyperlactation 5.794E-4 1.255E-2
8.857E-2
3.766E-1
 1 1
31 MP:0005671 abnormal response to transplant 6.084E-4 1.276E-2
8.999E-2
3.954E-1
 2 67
32 MP:0020186 altered susceptibility to bacterial infection 6.351E-4 1.290E-2
9.102E-2
4.128E-1
 3 337
33 MP:0002460 decreased immunoglobulin level 6.632E-4 1.306E-2
9.215E-2
4.311E-1
 3 342
34 MP:0009763 increased sensitivity to induced morbidity/mortality 6.979E-4 1.334E-2
9.412E-2
4.536E-1
 3 348
35 MP:0001835 abnormal antigen presentation 7.419E-4 1.339E-2
9.444E-2
4.822E-1
 2 74
36 MP:0000322 increased granulocyte number 7.459E-4 1.339E-2
9.444E-2
4.848E-1
 3 356
37 MP:0003721 increased tumor growth/size 7.620E-4 1.339E-2
9.444E-2
4.953E-1
 2 75
38 MP:0005264 glomerulosclerosis 8.883E-4 1.487E-2
1.049E-1
5.774E-1
 2 81
39 MP:0010307 abnormal tumor latency 9.103E-4 1.487E-2
1.049E-1
5.917E-1
 2 82
40 MP:0003075 altered response to CNS ischemic injury 9.325E-4 1.487E-2
1.049E-1
6.061E-1
 2 83
41 MP:0012440 abnormal neutrophil cell number 9.380E-4 1.487E-2
1.049E-1
6.097E-1
 3 385
42 MP:0004720 abnormal platelet morphology 1.034E-3 1.559E-2
1.100E-1
6.718E-1
 3 398
43 MP:0008077 abnormal CD8-positive, alpha-beta T cell number 1.049E-3 1.559E-2
1.100E-1
6.817E-1
 3 400
44 MP:0005606 increased bleeding time 1.120E-3 1.559E-2
1.100E-1
7.279E-1
 2 91
45 MP:0009548 abnormal platelet aggregation 1.144E-3 1.559E-2
1.100E-1
7.439E-1
 2 92
46 MP:0030603 increased sperm number 1.159E-3 1.559E-2
1.100E-1
7.531E-1
 1 2
47 MP:0002942 decreased circulating alanine transaminase level 1.169E-3 1.559E-2
1.100E-1
7.600E-1
 2 93
48 MP:0013662 decreased myeloid cell number 1.176E-3 1.559E-2
1.100E-1
7.643E-1
 3 416
49 MP:0000249 abnormal blood vessel physiology 1.217E-3 1.559E-2
1.100E-1
7.914E-1
 3 421
50 MP:0000260 abnormal angiogenesis 1.251E-3 1.559E-2
1.100E-1
8.135E-1
 3 425
Show 45 more annotations

6: Domain [Display Chart] 9 input genes in category / 94 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 SM00199 SCY SMART 1.749E-4 6.017E-3 3.084E-2 1.644E-2 2 42
2 PF00048 IL8 Pfam 1.920E-4 6.017E-3 3.084E-2 1.805E-2 2 44
3 IPR001811 Chemokine IL8-like dom InterPro 1.920E-4 6.017E-3 3.084E-2 1.805E-2 2 44
4 PF15225 IL32 Pfam 4.804E-4 9.031E-3 4.629E-2 4.516E-2 1 1
5 IPR028067 IL-32 InterPro 4.804E-4 9.031E-3 4.629E-2 4.516E-2 1 1
6 3.90.340.10 - Gene3D 1.441E-3 9.285E-3 4.759E-2
1.354E-1
 1 3
7 PS60001 NOS PROSITE 1.441E-3 9.285E-3 4.759E-2
1.354E-1
 1 3
8 IPR012144 NOS euk InterPro 1.441E-3 9.285E-3 4.759E-2
1.354E-1
 1 3
9 IPR004030 NOS N InterPro 1.441E-3 9.285E-3 4.759E-2
1.354E-1
 1 3
10 PF02898 NO synthase Pfam 1.441E-3 9.285E-3 4.759E-2
1.354E-1
 1 3
11 PF00168 C2 Pfam 1.691E-3 9.285E-3 4.759E-2
1.590E-1
 2 131
12 SM00239 C2 SMART 1.848E-3 9.285E-3 4.759E-2
1.737E-1
 2 137
13 IPR008097 CX3CL1 InterPro 1.920E-3 9.285E-3 4.759E-2
1.805E-1
 1 4
14 PS50004 C2 PROSITE 1.983E-3 9.285E-3 4.759E-2
1.864E-1
 2 142
15 2.60.40.150 - Gene3D 2.152E-3 9.285E-3 4.759E-2
2.023E-1
 2 148
16 IPR014772 Munc13 dom-2 InterPro 2.400E-3 9.285E-3 4.759E-2
2.256E-1
 1 5
17 PS51259 MHD2 PROSITE 2.400E-3 9.285E-3 4.759E-2
2.256E-1
 1 5
18 PF10540 Membr traf MHD Pfam 2.400E-3 9.285E-3 4.759E-2
2.256E-1
 1 5
19 IPR019558 Munc13 subgr dom-2 InterPro 2.400E-3 9.285E-3 4.759E-2
2.256E-1
 1 5
20 IPR000008 C2 dom InterPro 2.633E-3 9.285E-3 4.759E-2
2.475E-1
 2 164
21 IPR020863 MACPF CS InterPro 2.879E-3 9.285E-3 4.759E-2
2.706E-1
 1 6
22 PF00667 FAD binding 1 Pfam 2.879E-3 9.285E-3 4.759E-2
2.706E-1
 1 6
23 1.20.990.10 - Gene3D 2.879E-3 9.285E-3 4.759E-2
2.706E-1
 1 6
24 IPR003097 FAD-binding 1 InterPro 2.879E-3 9.285E-3 4.759E-2
2.706E-1
 1 6
25 IPR023173 NADPH Cyt P450 Rdtase dom3 InterPro 2.879E-3 9.285E-3 4.759E-2
2.706E-1
 1 6
26 IPR014770 Munc13 1 InterPro 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
27 PS51412 MACPF 2 PROSITE 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
28 IPR010439 CAPS dom InterPro 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
29 PS51258 MHD1 PROSITE 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
30 PF08246 Inhibitor I29 Pfam 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
31 IPR013201 Prot inhib I29 InterPro 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
32 PF06292 DUF1041 Pfam 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
33 PS00279 MACPF 1 PROSITE 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
34 SM00848 Inhibitor I29 SMART 3.358E-3 9.285E-3 4.759E-2
3.157E-1
 1 7
35 PS50902 FLAVODOXIN LIKE PROSITE 3.837E-3 9.492E-3 4.866E-2
3.607E-1
 1 8
36 IPR008254 Flavodoxin/NO synth InterPro 3.837E-3 9.492E-3 4.866E-2
3.607E-1
 1 8
37 IPR001094 Flavdoxin-like InterPro 3.837E-3 9.492E-3 4.866E-2
3.607E-1
 1 8
38 PF00258 Flavodoxin 1 Pfam 3.837E-3 9.492E-3 4.866E-2
3.607E-1
 1 8
39 IPR015373 Interferon/interleukin rcp dom InterPro 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
40 IPR001709 Flavoprot Pyr Nucl cyt Rdtase InterPro 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
41 3.40.50.360 - Gene3D 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
42 PF09294 Interfer-bind Pfam 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
43 IPR001862 MAC perforin InterPro 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
44 IPR025661 Pept asp AS InterPro 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
45 IPR029039 Flavoprotein-like dom InterPro 4.795E-3 1.002E-2
5.134E-2
4.507E-1
 1 10
46 IPR025660 Pept his AS InterPro 5.273E-3 1.010E-2
5.175E-2
4.957E-1
 1 11
47 PF01823 MACPF Pfam 5.273E-3 1.010E-2
5.175E-2
4.957E-1
 1 11
48 IPR001433 OxRdtase FAD/NAD-bd InterPro 5.751E-3 1.010E-2
5.175E-2
5.406E-1
 1 12
49 IPR020864 MACPF InterPro 5.751E-3 1.010E-2
5.175E-2
5.406E-1
 1 12
50 PF01108 Tissue fac Pfam 5.751E-3 1.010E-2
5.175E-2
5.406E-1
 1 12
Show 45 more annotations

7: Pathway [Display Chart] 9 input genes in category / 121 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 375172 Salmonella infection BioSystems: KEGG 2.604E-7 3.151E-5 1.694E-4 3.151E-5 4 86
2 138000 IL23-mediated signaling events BioSystems: Pathway Interaction Database 2.005E-6 1.213E-4 6.522E-4 2.426E-4 3 37
3 147809 Chagas disease (American trypanosomiasis) BioSystems: KEGG 4.327E-5 1.745E-3 9.385E-3 5.236E-3 3 102
4 213780 Tuberculosis BioSystems: KEGG 2.303E-4 6.968E-3 3.747E-2 2.787E-2 3 179
5 1470924 Interleukin-10 signaling BioSystems: REACTOME 5.368E-4 1.299E-2
6.985E-2
6.495E-2
 2 49
6 83051 Cytokine-cytokine receptor interaction BioSystems: KEGG 7.691E-4 1.551E-2
8.340E-2
9.306E-2
 3 270
7 144181 Leishmaniasis BioSystems: KEGG 1.189E-3 2.055E-2
1.105E-1
1.438E-1
 2 73
8 200309 Rheumatoid arthritis BioSystems: KEGG 1.800E-3 2.330E-2
1.253E-1
2.178E-1
 2 90
9 1474301 IL-17 signaling pathway BioSystems: KEGG 1.921E-3 2.330E-2
1.253E-1
2.324E-1
 2 93
10 167324 Amoebiasis BioSystems: KEGG 2.045E-3 2.330E-2
1.253E-1
2.474E-1
 2 96
11 695200 HIF-1 signaling pathway BioSystems: KEGG 2.260E-3 2.330E-2
1.253E-1
2.735E-1
 2 101
12 812256 TNF signaling pathway BioSystems: KEGG 2.579E-3 2.330E-2
1.253E-1
3.121E-1
 2 108
13 169642 Toxoplasmosis BioSystems: KEGG 2.820E-3 2.330E-2
1.253E-1
3.412E-1
 2 113
14 1470923 Interleukin-4 and 13 signaling BioSystems: REACTOME 2.869E-3 2.330E-2
1.253E-1
3.471E-1
 2 114
15 PW:0000506 endothelin signaling Pathway Ontology 2.889E-3 2.330E-2
1.253E-1
3.495E-1
 1 4
16 703092 citrulline-nitric oxide cycle BioSystems: BIOCYC 3.610E-3 2.730E-2
1.468E-1
4.368E-1
 1 5
17 83079 Natural killer cell mediated cytotoxicity BioSystems: KEGG 3.882E-3 2.745E-2
1.476E-1
4.697E-1
 2 133
18 83060 Apoptosis BioSystems: KEGG 4.173E-3 2.745E-2
1.476E-1
5.049E-1
 2 138
19 1457780 Neutrophil degranulation BioSystems: REACTOME 4.311E-3 2.745E-2
1.476E-1
5.216E-1
 3 492
20 122191 NOD-like receptor signaling pathway BioSystems: KEGG 6.265E-3 3.689E-2
1.984E-1
7.581E-1
 2 170
21 217173 Influenza A BioSystems: KEGG 6.482E-3 3.689E-2
1.984E-1
7.843E-1
 2 173
22 99051 Chemokine signaling pathway BioSystems: KEGG 7.152E-3 3.689E-2
1.984E-1
8.653E-1
 2 182
23 PW:0000244 Angiotensin II signaling Pathway Ontology 7.208E-3 3.689E-2
1.984E-1
8.722E-1
 1 10
24 377873 Herpes simplex infection BioSystems: KEGG 7.382E-3 3.689E-2
1.984E-1
8.932E-1
 2 185
25 P00031 Inflammation mediated by chemokine and cytokine signaling pathway PantherDB 7.852E-3 3.689E-2
1.984E-1
9.501E-1
 2 191
26 M3075 Granzyme A mediated Apoptosis Pathway MSigDB C2 BIOCARTA (v6.0) 7.926E-3 3.689E-2
1.984E-1
9.591E-1
 1 11
27 1269198 Endosomal/Vacuolar pathway BioSystems: REACTOME 8.644E-3 3.874E-2
2.083E-1
1.000E0
 1 12
28 M15513 D4-GDI Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 9.361E-3 4.045E-2
2.175E-1
1.000E0
 1 13
29 1269205 Trafficking and processing of endosomal TLR BioSystems: REACTOME 1.008E-2 4.065E-2
2.186E-1
1.000E0
 1 14
30 1269315 Regulation of IFNG signaling BioSystems: REACTOME 1.008E-2 4.065E-2
2.186E-1
1.000E0
 1 14
31 M1462 CTL mediated immune response against target cells MSigDB C2 BIOCARTA (v6.0) 1.079E-2 4.213E-2
2.266E-1
1.000E0
 1 15
32 M6231 NO2-dependent IL 12 Pathway in NK cells MSigDB C2 BIOCARTA (v6.0) 1.223E-2 4.348E-2
2.338E-1
1.000E0
 1 17
33 1269514 RHO GTPases activate CIT BioSystems: REACTOME 1.223E-2 4.348E-2
2.338E-1
1.000E0
 1 17
34 1269510 RHO GTPases Activate ROCKs BioSystems: REACTOME 1.223E-2 4.348E-2
2.338E-1
1.000E0
 1 17
35 M2349 Pertussis toxin-insensitive CCR5 Signaling in Macrophage MSigDB C2 BIOCARTA (v6.0) 1.294E-2 4.348E-2
2.338E-1
1.000E0
 1 18
36 M9546 Chaperones modulate interferon Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 1.366E-2 4.348E-2
2.338E-1
1.000E0
 1 19
37 M6705 Th1/Th2 Differentiation MSigDB C2 BIOCARTA (v6.0) 1.366E-2 4.348E-2
2.338E-1
1.000E0
 1 19
38 M7997 Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. MSigDB C2 BIOCARTA (v6.0) 1.366E-2 4.348E-2
2.338E-1
1.000E0
 1 19
39 82943 Arginine biosynthesis BioSystems: KEGG 1.508E-2 4.530E-2
2.436E-1
1.000E0
 1 21
40 PW:0000050 arginine and proline metabolic Pathway Ontology 1.508E-2 4.530E-2
2.436E-1
1.000E0
 1 21
41 P05734 Synaptic vesicle trafficking PantherDB 1.651E-2 4.530E-2
2.436E-1
1.000E0
 1 23
42 1269511 RHO GTPases activate PAKs BioSystems: REACTOME 1.651E-2 4.530E-2
2.436E-1
1.000E0
 1 23
43 M17902 Caspase Cascade in Apoptosis MSigDB C2 BIOCARTA (v6.0) 1.651E-2 4.530E-2
2.436E-1
1.000E0
 1 23
44 1270307 Sema4D induced cell migration and growth-cone collapse BioSystems: REACTOME 1.722E-2 4.530E-2
2.436E-1
1.000E0
 1 24
45 1269343 Nitric oxide stimulates guanylate cyclase BioSystems: REACTOME 1.722E-2 4.530E-2
2.436E-1
1.000E0
 1 24
46 PW:0000243 vascular endothelial growth factor signaling Pathway Ontology 1.722E-2 4.530E-2
2.436E-1
1.000E0
 1 24
47 1268762 ATF4 activates genes BioSystems: REACTOME 1.936E-2 4.856E-2
2.611E-1
1.000E0
 1 27
48 1270305 Sema4D in semaphorin signaling BioSystems: REACTOME 1.936E-2 4.856E-2
2.611E-1
1.000E0
 1 27
49 P00035 Interferon-gamma signaling pathway PantherDB 2.007E-2 4.856E-2
2.611E-1
1.000E0
 1 28
50 137936 IL12 signaling mediated by STAT4 BioSystems: Pathway Interaction Database 2.007E-2 4.856E-2
2.611E-1
1.000E0
 1 28
Show 45 more annotations

8: Pubmed [Display Chart] 9 input genes in category / 5258 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20503287 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Pubmed 5.125E-10 9.667E-7 8.841E-6 2.695E-6 5 204
2 19258923 Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Pubmed 5.253E-10 9.667E-7 8.841E-6 2.762E-6 5 205
3 17703412 Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. Pubmed 5.516E-10 9.667E-7 8.841E-6 2.900E-6 5 207
4 19291698 Negative feedback regulation of IL-32 production by iNOS activation in response to dsRNA or influenza virus infection. Pubmed 4.936E-8 4.326E-5 3.956E-4 2.595E-4 2 2
5 19147409 Investigation of chromosome 17 candidate genes in susceptibility to TB in a South African population. Pubmed 4.936E-8 4.326E-5 3.956E-4 2.595E-4 2 2
6 16352737 A functional promoter polymorphism in monocyte chemoattractant protein-1 is associated with increased susceptibility to pulmonary tuberculosis. Pubmed 4.936E-8 4.326E-5 3.956E-4 2.595E-4 2 2
7 24981451 CXCL1 inhibits airway smooth muscle cell migration through the decoy receptor Duffy antigen receptor for chemokines. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
8 18710388 Characterization of PRF1, STX11 and UNC13D genotype-phenotype correlations in familial hemophagocytic lymphohistiocytosis. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
9 18227174 NK cells and gamma interferon coordinate the formation and function of hepatic granulomas in mice infected with the Francisella tularensis live vaccine strain. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
10 21881043 Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
11 21606480 Perforin is a critical physiologic regulator of T-cell activation. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
12 19906815 Lysophosphatidic acid up-regulates expression of growth-regulated oncogene-alpha, interleukin-8, and monocyte chemoattractant protein-1 in human first-trimester trophoblasts: possible roles in angiogenesis and immune regulation. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
13 17343612 Up-regulation of Fas (CD95) expression in tumour cells in vivo. Pubmed 1.481E-7 5.989E-5 5.476E-4 7.785E-4 2 3
14 22183310 Local vs. systemic mononuclear phagocytes in age-related macular degeneration and their regulation by CCL2-CCR2 and CX3CL1-CX3CR1 chemokine signalling. Pubmed 2.961E-7 8.194E-5 7.493E-4 1.557E-3 2 4
15 18311812 Genetic loci contributing to hemophagocytic lymphohistiocytosis do not confer susceptibility to systemic-onset juvenile idiopathic arthritis. Pubmed 2.961E-7 8.194E-5 7.493E-4 1.557E-3 2 4
16 22125641 Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer. Pubmed 2.961E-7 8.194E-5 7.493E-4 1.557E-3 2 4
17 30296742 The association between inflammatory markers (iNOS, HO-1, IL-33, MIP-1β) and depression with and without posttraumatic stress disorder. Pubmed 2.961E-7 8.194E-5 7.493E-4 1.557E-3 2 4
18 20089706 Peroxynitrite-dependent killing of cancer cells and presentation of released tumor antigens by activated dendritic cells. Pubmed 2.961E-7 8.194E-5 7.493E-4 1.557E-3 2 4
19 16278825 Mutation spectrum in children with primary hemophagocytic lymphohistiocytosis: molecular and functional analyses of PRF1, UNC13D, STX11, and RAB27A. Pubmed 2.961E-7 8.194E-5 7.493E-4 1.557E-3 2 4
20 22075702 Th-1 lymphocytes induce dendritic cell tumor killing activity by an IFN-γ-dependent mechanism. Pubmed 4.934E-7 1.179E-4 1.078E-3 2.594E-3 2 5
21 21220697 Chemokine transcripts as targets of the RNA-binding protein HuR in human airway epithelium. Pubmed 4.934E-7 1.179E-4 1.078E-3 2.594E-3 2 5
22 20301617 Hemophagocytic Lymphohistiocytosis, Familial Pubmed 4.934E-7 1.179E-4 1.078E-3 2.594E-3 2 5
23 21624938 Hemophagocytosis causes a consumptive anemia of inflammation. Pubmed 7.400E-7 1.496E-4 1.368E-3 3.891E-3 2 6
24 15944263 Peptide-specific CD8 T regulatory cells use IFN-gamma to elaborate TGF-beta-based suppression. Pubmed 7.400E-7 1.496E-4 1.368E-3 3.891E-3 2 6
25 21674762 Screening the PRF1, UNC13D, STX11, SH2D1A, XIAP, and ITK gene mutations in Chinese children with Epstein-Barr virus-associated hemophagocytic lymphohistiocytosis. Pubmed 7.400E-7 1.496E-4 1.368E-3 3.891E-3 2 6
26 24061165 CD8 T cells regulate allergic contact dermatitis by modulating CCR2-dependent TNF/iNOS-expressing Ly6C+ CD11b+ monocytic cells. Pubmed 7.400E-7 1.496E-4 1.368E-3 3.891E-3 2 6
27 23128233 Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Pubmed 7.683E-7 1.496E-4 1.368E-3 4.040E-3 4 342
28 29369549 [Association of polymorphic markers of chemokine genes, their receptors, and CD14 gene with coronary atherosclerosis]. Pubmed 1.036E-6 1.816E-4 1.660E-3 5.447E-3 2 7
29 17062130 Polymorphisms within inflammatory genes and colorectal cancer. Pubmed 1.036E-6 1.816E-4 1.660E-3 5.447E-3 2 7
30 13679391 A high endothelial venule-expressing promiscuous chemokine receptor DARC can bind inflammatory, but not lymphoid, chemokines and is dispensable for lymphocyte homing under physiological conditions. Pubmed 1.036E-6 1.816E-4 1.660E-3 5.447E-3 2 7
31 19247692 Analyses of associations with asthma in four asthma population samples from Canada and Australia. Pubmed 1.124E-6 1.907E-4 1.744E-3 5.911E-3 3 92
32 19923462 IFN-gamma expressed by T cells regulates the persistence of antigen presentation by limiting the survival of dendritic cells. Pubmed 1.381E-6 2.201E-4 2.012E-3 7.262E-3 2 8
33 26076475 Anti-Inflammatory and Anti-Thrombotic Effects of the Fungal Metabolite Galiellalactone in Apolipoprotein E-Deficient Mice. Pubmed 1.381E-6 2.201E-4 2.012E-3 7.262E-3 2 8
34 24667918 Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02 AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction. Pubmed 1.676E-6 2.591E-4 2.370E-3 8.811E-3 3 105
35 10072530 Role of innate and adaptive immunity in the outcome of primary infection with Chlamydia pneumoniae, as analyzed in genetically modified mice. Pubmed 1.775E-6 2.593E-4 2.371E-3 9.335E-3 2 9
36 14742542 Mechanisms of immunity to Ehrlichia muris: a model of monocytotropic ehrlichiosis. Pubmed 1.775E-6 2.593E-4 2.371E-3 9.335E-3 2 9
37 26719799 The α7-nicotinic receptor is upregulated in immune cells from HIV-seropositive women: consequences to the cholinergic anti-inflammatory response. Pubmed 2.219E-6 3.070E-4 2.808E-3 1.167E-2 2 10
38 10438970 Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis. Pubmed 2.219E-6 3.070E-4 2.808E-3 1.167E-2 2 10
39 20673868 A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM). Pubmed 9.343E-6 6.280E-4 5.743E-3 4.913E-2 3 186
40 20452482 Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes. Pubmed 9.494E-6 6.280E-4 5.743E-3 4.992E-2 3 187
41 27626662 STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation. Pubmed 1.034E-5 6.280E-4 5.743E-3
5.438E-2
 2 21
42 23728617 Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival. Pubmed 1.359E-5 6.280E-4 5.743E-3
7.144E-2
 2 24
43 19773451 Role of inflammation gene polymorphisms on pain severity in lung cancer patients. Pubmed 2.596E-5 6.280E-4 5.743E-3
1.365E-1
 2 33
44 20811626 Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. Pubmed 3.097E-5 6.280E-4 5.743E-3
1.628E-1
 2 36
45 19012493 Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer. Pubmed 5.772E-5 6.280E-4 5.743E-3
3.035E-1
 2 49
46 12089333 HIV envelope induces a cascade of cell signals in non-proliferating target cells that favor virus replication. Pubmed 9.568E-5 6.280E-4 5.743E-3
5.031E-1
 2 63
47 20416077 Identification of type 2 diabetes-associated combination of SNPs using support vector machine. Pubmed 1.999E-4 6.280E-4 5.743E-3
1.000E0
 2 91
48 15755897 A functional analysis of the putative polymorphisms A91V and N252S and 22 missense perforin mutations associated with familial hemophagocytic lymphohistiocytosis. Pubmed 2.356E-4 6.280E-4 5.743E-3
1.000E0
 1 1
49 25943983 Is there a role for monocyte chemoattractant protein-1 in delirium? Novel observations in elderly hip fracture patients. Pubmed 2.356E-4 6.280E-4 5.743E-3
1.000E0
 1 1
50 29420734 Convergent pathways of the hyperferritinemic syndromes. Pubmed 2.356E-4 6.280E-4 5.743E-3
1.000E0
 1 1
Show 45 more annotations

9: Interaction [Display Chart] 9 input genes in category / 535 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:ACKR1 ACKR1 interactions 1.032E-5 5.520E-3 3.787E-2 5.520E-3 2 10

10: Cytoband [Display Chart] 9 input genes in category / 8 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 17q11.2-q12 17q11.2-q12 1.258E-6 1.006E-5 2.735E-5 1.006E-5 2 7
2 10q22 10q22 4.923E-3 1.451E-2 3.943E-2 3.939E-2 1 19
3 4q21 4q21 5.440E-3 1.451E-2 3.943E-2 4.352E-2 1 21
4 21q22.11 21q22.11 1.650E-2 2.731E-2
7.422E-2
1.320E-1
 1 64
5 17q25.1 17q25.1 2.135E-2 2.731E-2
7.422E-2
1.708E-1
 1 83
6 22q13.1 22q13.1 2.288E-2 2.731E-2
7.422E-2
1.830E-1
 1 89
7 1q21 1q21 2.389E-2 2.731E-2
7.422E-2
1.911E-1
 1 93
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 6 input genes in category / 36 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 8 input genes in category / 10 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 483 Chemokine ligands|Endogenous ligands genenames.org 1.659E-4 1.659E-3 4.860E-3 1.659E-3 2 45
2 836 UNC13 homologs genenames.org 1.758E-3 7.323E-3 2.145E-2 1.758E-2 1 4
3 599 CD molecules|Interferon receptors genenames.org 2.197E-3 7.323E-3 2.145E-2 2.197E-2 1 5
4 542 Endogenous ligands genenames.org 4.493E-3 1.096E-2 3.211E-2 4.493E-2 2 237
5 1098 Myosin heavy chains genenames.org 6.578E-3 1.096E-2 3.211E-2
6.578E-2
 1 15
6 470 Cathepsins genenames.org 6.578E-3 1.096E-2 3.211E-2
6.578E-2
 1 15
7 823 C2 domain containing|Calpains genenames.org 1.572E-2 2.246E-2
6.579E-2
1.572E-1
 1 36
8 601 Interleukins|PDZ domain containing genenames.org 1.876E-2 2.344E-2
6.867E-2
1.876E-1
 1 43
Show 3 more annotations

13: Coexpression [Display Chart] 9 input genes in category / 1527 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5950 Genes up-regulated during transplant rejection. MSigDB H: Hallmark Gene Sets (v6.0) 5.624E-9 8.588E-6 6.792E-5 8.588E-6 5 200
2 18707017-Table1 Human Leukemia Kalwitz08 35genes GeneSigDB 2.007E-7 1.211E-4 9.574E-4 3.065E-4 3 32
3 16081686-SuppTable2 Human Lymphoma Tome05 357genes GeneSigDB 2.378E-7 1.211E-4 9.574E-4 3.632E-4 4 155
4 M1520 Genes up-regulated in HeLa cells (cervical carcinoma) at 4 h after stimulation with TNF [GeneID=7124]. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.995E-7 3.816E-4 3.018E-3 1.526E-3 3 54
5 16191192-Table2 Human StemCell Tian05 68genes GeneSigDB 1.840E-6 5.618E-4 4.443E-3 2.809E-3 3 66
6 M1673 Genes up-regulated in MMEC cells (myometrial endothelium) at 3 h after VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.602E-6 6.622E-4 5.237E-3 3.973E-3 3 74
7 M11290 Chemokine genes up-regulated within 2 hr of c-Myc [GeneID=4609] activation in a mouse model of Myc-induced pancreatic beta-cell tumorigenesis. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.762E-6 7.729E-4 6.112E-3 5.744E-3 2 8
8 16397233-Table1 Mouse Liver Ryschich06 100genes UpRegulated GeneSigDB 4.244E-6 7.729E-4 6.112E-3 6.480E-3 3 87
9 15642130-TableS1 Rat Immune Rioja04 438genes GeneSigDB 4.555E-6 7.729E-4 6.112E-3 6.956E-3 4 325
10 15885264-Table1 Mouse Lung not cancer Lee05 127genes GeneSigDB 7.916E-6 1.036E-3 8.192E-3 1.209E-2 3 107
11 M5487 Hepatic graft versus host disease (GVHD), day 7: up-regulated in allogeneic vs syngeneic bone marrow transplant. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.916E-6 1.036E-3 8.192E-3 1.209E-2 3 107
12 M1565 Genes up-regulated in MMEC cells (myometrial endothelium) by VEGFA [GeneID=7422] stimulation. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.140E-6 1.036E-3 8.192E-3 1.243E-2 3 108
13 20042535-TableS2a Human InVitro Haouzi10 14genes GeneSigDB 1.047E-5 1.230E-3 9.724E-3 1.598E-2 2 13
14 M19618 Hepatic graft versus host disease (GVHD), day 35: genes up-regulated in allogeneic vs syngeneic bone marrow transplant. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.453E-5 1.585E-3 1.254E-2 2.219E-2 3 131
15 20460173-ImmPortAntimicrobials Human Immune Kong10 544genes ImmPort Antimicrobials GeneSigDB 1.937E-5 1.842E-3 1.457E-2 2.958E-2 4 469
16 16529784-Table5 Rat Lung not cancer Gate06 26genes GeneSigDB 2.051E-5 1.842E-3 1.457E-2 3.132E-2 2 18
17 M10102 Top 20 positive significant genes associated with malignant fibrous histiocytoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.051E-5 1.842E-3 1.457E-2 3.132E-2 2 18
18 M1171 Known and putative targets of NFKB1 [GeneID=4790] identified among the ATM [GeneID=472] dependent, late responders to ionizing radiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.292E-5 1.842E-3 1.457E-2 3.500E-2 2 19
19 18358739-Table1a Human LungNotCaner Kent08 23genes GeneSigDB 2.292E-5 1.842E-3 1.457E-2 3.500E-2 2 19
20 M1304 Genes down-regulated in SEND cells (skin endothelium) at hypoxia with ELK3 [GeneID=2004] knockdown by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.452E-5 1.852E-3 1.464E-2 3.744E-2 3 156
21 17023518-Table1 Mouse Lung not cancer Chen06 23genes GeneSigDB 2.546E-5 1.852E-3 1.464E-2 3.888E-2 2 20
22 M1459 Genes down-regulated in BEC (blood endothelial cells) compared to LEC (lymphatic endothelial cells). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.744E-5 1.868E-3 1.477E-2 4.190E-2 3 162
23 M5754 Genes down-regulated more than two-fold in lymphoblastoid cell lines from European population compared to those from Asian population. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.814E-5 1.868E-3 1.477E-2 4.297E-2 2 21
24 14996724-Table1Up Human Ovarian Liu04 23genes GeneSigDB 3.095E-5 1.969E-3 1.557E-2 4.725E-2 2 22
25 M7454 Genes down-regulated in CD4 [GeneID=920] T cells: STAT3 [GeneID=6774] knockout versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 4.918E-5 2.618E-3 2.071E-2
7.509E-2
 3 197
26 M4606 Genes down-regulated in comparison of CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 7 versus CD25- T cells treated with IL4 [GeneID=3565] at day 7. MSigDB C7: Immunologic Signatures (v6.0) 5.068E-5 2.618E-3 2.071E-2
7.738E-2
 3 199
27 M9596 Genes up-regulated in thymic T conv: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 5.068E-5 2.618E-3 2.071E-2
7.738E-2
 3 199
28 M9568 Genes up-regulated in KLRG1 low [GeneID=10219] CD8 T effector cells during infection: ID2 [GeneID=10219] knockout versus BCL2L11 [GeneID=10018] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.068E-5 2.618E-3 2.071E-2
7.738E-2
 3 199
29 M5890 Genes regulated by NF-kB in response to TNF [GeneID=7124]. MSigDB H: Hallmark Gene Sets (v6.0) 5.144E-5 2.618E-3 2.071E-2
7.855E-2
 3 200
30 M4603 Genes down-regulated in comparison of CD25+ T cells treated with IL4 [GeneID=3565] versus CD25- T cells treated with IL4 [GeneID=3565] at day 5. MSigDB C7: Immunologic Signatures (v6.0) 5.144E-5 2.618E-3 2.071E-2
7.855E-2
 3 200
31 18483624-Table1 Human Stomach Marcos08 45genes GeneSigDB 6.218E-5 2.967E-3 2.347E-2
9.495E-2
 2 31
32 15345586-Table1 Human StemCell Giroux05 34genes GeneSigDB 6.218E-5 2.967E-3 2.347E-2
9.495E-2
 2 31
33 M19826 Genes up-regulated in BxPC3 cells (pancreatic cancer) after treatment with TNF [GeneID=7124] or IKI-1, an inhibitor of IkappaB kinase (IKK). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.109E-5 3.271E-3 2.587E-2
1.086E-1
 3 223
34 16585964-SuppTable1 Mouse Lung not cancer Thimmulappa06 38genes GeneSigDB 7.497E-5 3.271E-3 2.587E-2
1.145E-1
 2 34
35 M1983 Genes down-regulated in A375 cells (melanoma) treated with KINK-1, a small molecule inhibitor of NFKB. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.497E-5 3.271E-3 2.587E-2
1.145E-1
 2 34
36 19818417-Table2 Human Lung not cancer Kent10 40genes GeneSigDB 8.416E-5 3.570E-3 2.823E-2
1.285E-1
 2 36
37 18172295-SuppTable1 Human Bone Heller08 284genes GeneSigDB 9.628E-5 3.974E-3 3.143E-2
1.470E-1
 3 247
38 M10454 Genes up-regulated in pulpal tissue extracted from carious teeth. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.034E-4 4.154E-3 3.285E-2
1.579E-1
 3 253
39 17295094-GeneList Human Breast VandenEynden07 269genes-hypoxia angiogenesis GeneSigDB 1.160E-4 4.540E-3 3.591E-2
1.771E-1
 3 263
40 M1325 NF-kB-controlled genes up-regulated in endothelial cells in response to viral GPCR protein. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.205E-4 4.598E-3 3.637E-2
1.839E-1
 2 43
41 M8776 Genes up-regulated in at least one of three multiple myeloma (MM) cell lines treated with the DNA hypomethylating agent decitabine (5-aza-2'-deoxycytidine) [PubChem=451668]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.425E-4 5.308E-3 4.198E-2
2.176E-1
 3 282
42 19249085-TableE4 Mouse Lung not cancer Lewis09 65genes GeneSigDB 1.567E-4 5.663E-3 4.479E-2
2.393E-1
 2 49
43 16479545-Table2 Mouse Lung not cancer Kahnert06 70genes GeneSigDB 1.632E-4 5.663E-3 4.479E-2
2.492E-1
 2 50
44 15774477-Table1 Rat StemCell KaplanAlbuquerque 75genes GeneSigDB 1.632E-4 5.663E-3 4.479E-2
2.492E-1
 2 50
45 19249085-TableE3 Mouse Lung not cancer Lewis09 76genes GeneSigDB 1.905E-4 6.463E-3
5.111E-2
2.908E-1
 2 54
46 17617570-Table2 Mouse StemCell Okuda07 64genes GeneSigDB 1.976E-4 6.480E-3
5.124E-2
3.018E-1
 2 55
47 20418243-SuppTable1a Human Leukemia Chiaretti10 405genes GeneSigDB 1.994E-4 6.480E-3
5.124E-2
3.045E-1
 3 316
48 14990357-Table3 Rat Lung not cancer Wagenaar04 78genes GeneSigDB 2.198E-4 6.994E-3
5.531E-2
3.357E-1
 2 58
49 15958557-Table1 Mouse StemCell KronesHerzig05 70enes GeneSigDB 2.432E-4 7.435E-3
5.880E-2
3.714E-1
 2 61
50 19497124-TableS2 Human Breast Hernandez09 81genes GeneSigDB 2.513E-4 7.435E-3
5.880E-2
3.837E-1
 2 62
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 9 input genes in category / 1420 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Mucinous Colon Adenocarcinoma/2/1 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Mucinous Colon Adenocarcinoma/2/1 TCGA-Colorectal 8.395E-6 7.994E-3
6.264E-2
 1.192E-2 3 103
2 10X Human 68K PBMC CD8+ Cytotoxic T Subtype CD8+ Cytotoxic T-CD8+ Cytotoxic T c4 Top 200 Genes 10X Human 68K PBMC CD8+ Cytotoxic T Subtype CD8+ Cytotoxic T-CD8+ Cytotoxic T c4 Top 200 Genes 1.202E-5 7.994E-3
6.264E-2
 1.706E-2 4 392
3 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Non-Seminoma- Embryonal Carcinoma, Yolk Sac Tumor/3/1 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Non-Seminoma- Embryonal Carcinoma, Yolk Sac Tumor/3/1 TCGA-Testes 1.689E-5 7.994E-3
6.264E-2
 2.398E-2 3 130
4 JC hmvEC 500 JC hmvEC top-relative-expression-ranked 500 PCBC 3.055E-5 1.084E-2
8.498E-2
 4.338E-2 4 497
5 JC hmvEC 500 K1 JC hmvEC top-relative-expression-ranked 500 k-means-cluster#1 PCBC 8.111E-5 1.780E-2
1.395E-1
1.152E-1
 3 220
6 Human Cell Atlas Human Cell Atlas Myeloid Myeloid Subtype Eosinophil Top 200 Genes Human Cell Atlas Human Cell Atlas Myeloid Myeloid Subtype Eosinophil Top 200 Genes 2.132E-4 1.780E-2
1.395E-1
3.027E-1
 3 305
7 Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma2-C2-KC10 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma2-C2-KC10 Top 200 Genes 2.501E-4 1.780E-2
1.395E-1
3.551E-1
 3 322
8 10X Human 8K PBMC doublet Subtype doublet-T-cell B-cell doublet Top 200 Genes 10X Human 8K PBMC doublet Subtype doublet-T-cell B-cell doublet Top 200 Genes 2.640E-4 1.780E-2
1.395E-1
3.749E-1
 3 328
9 Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma3-C4-KC10 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma3-C4-KC10 Top 200 Genes 2.736E-4 1.780E-2
1.395E-1
3.885E-1
 3 332
10 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype CD163+ Macrophage Top 200 Genes 2.736E-4 1.780E-2
1.395E-1
3.885E-1
 3 332
11 Glioblastoma Single Cell Merged Vascular Subtype Vascular-Vascular.3 Top 200 Genes Glioblastoma Single Cell Merged Vascular Subtype Vascular-Vascular.3 Top 200 Genes 3.195E-4 1.780E-2
1.395E-1
4.537E-1
 3 350
12 10X Human 8K PBMC CD8 T cell Subtype CD8 T cell-GZMK CCL5 NKG7 Top 200 Genes 10X Human 8K PBMC CD8 T cell Subtype CD8 T cell-GZMK CCL5 NKG7 Top 200 Genes 3.359E-4 1.780E-2
1.395E-1
4.769E-1
 3 356
13 10X Human 8K PBMC CD8 T cells Subtype CD8 T cells-LYZ, S100A8, S100A9 Top 200 Genes 10X Human 8K PBMC CD8 T cells Subtype CD8 T cells-LYZ, S100A8, S100A9 Top 200 Genes 3.702E-4 1.780E-2
1.395E-1
5.257E-1
 3 368
14 10X Human 8K PBMC doublet Subtype doublet-B-cell T-cell doublet A Top 200 Genes 10X Human 8K PBMC doublet Subtype doublet-B-cell T-cell doublet A Top 200 Genes 3.731E-4 1.780E-2
1.395E-1
5.299E-1
 3 369
15 10X Human 8K PBMC CD8 T cells (CCL5, NKG7, GZMK) Subtype CD8 T cells (CCL5, NKG7, GZMK)-CD8 T cells subclass-F (LYZ, S100A8, S100A9) Top 200 Genes 10X Human 8K PBMC CD8 T cells (CCL5, NKG7, GZMK) Subtype CD8 T cells (CCL5, NKG7, GZMK)-CD8 T cells subclass-F (LYZ, S100A8, S100A9) Top 200 Genes 3.761E-4 1.780E-2
1.395E-1
5.341E-1
 3 370
16 10X Human 68K PBMC CD14+ Monocyte Subtype CD14+ Monocyte-CD14+ Monocyte c1 Top 200 Genes 10X Human 68K PBMC CD14+ Monocyte Subtype CD14+ Monocyte-CD14+ Monocyte c1 Top 200 Genes 3.881E-4 1.780E-2
1.395E-1
5.512E-1
 3 374
17 10X Human 68K PBMC CD56+ NK Subtype CD56+ NK-CD56+ NK c3 Top 200 Genes 10X Human 68K PBMC CD56+ NK Subtype CD56+ NK-CD56+ NK c3 Top 200 Genes 4.035E-4 1.780E-2
1.395E-1
5.730E-1
 3 379
18 10X Human 68K PBMC CD4+/CD45RA+/CD25- Naive T Subtype CD4+/CD45RA+/CD25- Naive T-CD4+/CD45RA+/CD25- Naive T c1 Top 200 Genes 10X Human 68K PBMC CD4+/CD45RA+/CD25- Naive T Subtype CD4+/CD45RA+/CD25- Naive T-CD4+/CD45RA+/CD25- Naive T c1 Top 200 Genes 4.035E-4 1.780E-2
1.395E-1
5.730E-1
 3 379
19 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Tumour RCC Renal cell carcinoma/Kidney Tumour RCC T6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Tumour RCC Renal cell carcinoma/Kidney Tumour RCC T6 Adult, Development, and Cancer types 4.123E-4 1.780E-2
1.395E-1
5.855E-1
 1 1
20 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Tumour RCC Nephron epithelium/Kidney Tumour RCC N6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Tumour RCC Nephron epithelium/Kidney Tumour RCC N6 Adult, Development, and Cancer types 4.123E-4 1.780E-2
1.395E-1
5.855E-1
 1 1
21 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour RCC PT-U/Kidney Tumour RCC PT6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour RCC PT-U/Kidney Tumour RCC PT6 Adult, Development, and Cancer types 4.123E-4 1.780E-2
1.395E-1
5.855E-1
 1 1
22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour RCC U U/Kidney Tumour RCC U6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour RCC U U/Kidney Tumour RCC U6 Adult, Development, and Cancer types 4.123E-4 1.780E-2
1.395E-1
5.855E-1
 1 1
23 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour RCC NK cell/Kidney Tumour RCC NK6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour RCC NK cell/Kidney Tumour RCC NK6 Adult, Development, and Cancer types 4.123E-4 1.780E-2
1.395E-1
5.855E-1
 1 1
24 10X Human 8K PBMC T cell Subtype T cell-GNLY NKG7 GZMB Top 200 Genes 10X Human 8K PBMC T cell Subtype T cell-GNLY NKG7 GZMB Top 200 Genes 4.130E-4 1.780E-2
1.395E-1
5.864E-1
 3 382
25 10X Human 8K PBMC unknown Subtype unknown-unknown Top 200 Genes 10X Human 8K PBMC unknown Subtype unknown-unknown Top 200 Genes 4.161E-4 1.780E-2
1.395E-1
5.909E-1
 3 383
26 DevelopingKidney e15.5 Endothelial cells emap-29977 500 DevelopingKidney e15.5 Endothelial cells emap-29977 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.193E-4 1.780E-2
1.395E-1
5.955E-1
 3 384
27 gudmap developingKidney e15.5 Endothelial cells 500 DevelopingKidney e15.5 Endothelial cells emap-29965 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.193E-4 1.780E-2
1.395E-1
5.955E-1
 3 384
28 10X Human 68K PBMC CD56+ NK Subtype CD56+ NK-CD56+ NK c9 Top 200 Genes 10X Human 68K PBMC CD56+ NK Subtype CD56+ NK-CD56+ NK c9 Top 200 Genes 4.225E-4 1.780E-2
1.395E-1
6.000E-1
 3 385
29 10X Human 68K PBMC CD56+ NK Subtype CD56+ NK-CD56+ NK c5 Top 200 Genes 10X Human 68K PBMC CD56+ NK Subtype CD56+ NK-CD56+ NK c5 Top 200 Genes 4.225E-4 1.780E-2
1.395E-1
6.000E-1
 3 385
30 10X Human 8K PBMC NK cells (GZMB, SPON2, GNLY) Subtype NK cells (GZMB, SPON2, GNLY)-NK cells subclass-0 (FGFBP2, GZMB, SPON2) Top 200 Genes 10X Human 8K PBMC NK cells (GZMB, SPON2, GNLY) Subtype NK cells (GZMB, SPON2, GNLY)-NK cells subclass-0 (FGFBP2, GZMB, SPON2) Top 200 Genes 4.225E-4 1.780E-2
1.395E-1
6.000E-1
 3 385
31 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Tumour VHL RCC Endothelium/Kidney Tumour VHL RCC N9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Tumour VHL RCC Endothelium/Kidney Tumour VHL RCC N9 Adult, Development, and Cancer types 4.239E-4 1.780E-2
1.395E-1
6.019E-1
 2 76
32 gudmap dev gonad e11.5 M ReproVasc Flk k4 500 dev gonad e11.5 M ReproVasc Flk k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 4.239E-4 1.780E-2
1.395E-1
6.019E-1
 2 76
33 10X Human 8K PBMC CD14+ Monocytes Subtype CD14+ Monocytes-CD3D, TRAC, LTB Top 200 Genes 10X Human 8K PBMC CD14+ Monocytes Subtype CD14+ Monocytes-CD3D, TRAC, LTB Top 200 Genes 4.290E-4 1.780E-2
1.395E-1
6.092E-1
 3 387
34 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter NK cell/Ureter Normal RCC NK cell/Ureter Normal RCC NK13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter NK cell/Ureter Normal RCC NK cell/Ureter Normal RCC NK13 Adult, Development, and Cancer types 4.351E-4 1.780E-2
1.395E-1
6.178E-1
 2 77
35 10X Human 68K PBMC Dendritic Subtype Dendritic-Dendritic c4 Top 200 Genes 10X Human 68K PBMC Dendritic Subtype Dendritic-Dendritic c4 Top 200 Genes 4.388E-4 1.780E-2
1.395E-1
6.231E-1
 3 390
36 gudmap kidney e13.5 Podocyte MafB k4 1000 kidney e13.5 Podocyte MafB k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.933E-4 1.855E-2
1.454E-1
7.005E-1
 2 82
37 Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Immune cells (IMM)/late fetal Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Immune cells (IMM)/late fetal Fetal, Development 5.054E-4 1.855E-2
1.454E-1
7.176E-1
 2 83
38 Lungmap Mouse Lung E16.5 Myeloid Lungmap Mouse Lung E16.5 Myeloid Lungmap CCHMC 5.188E-4 1.855E-2
1.454E-1
7.368E-1
 3 413
39 gudmap dev gonad e11.5 M ReproVasc Flk 500 dev gonad e11.5 M ReproVasc Flk top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 5.225E-4 1.855E-2
1.454E-1
7.420E-1
 3 414
40 GSM854271 500 Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2 Immgen.org, GSE15907 5.225E-4 1.855E-2
1.454E-1
7.420E-1
 3 414
41 GSM777055 100 Stromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4 Immgen.org, GSE15907 5.425E-4 1.879E-2
1.472E-1
7.703E-1
 2 86
42 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour PapRCC R U/Kidney Tumour PapRCC R6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour PapRCC R U/Kidney Tumour PapRCC R6 Adult, Development, and Cancer types 5.939E-4 2.008E-2
1.573E-1
8.433E-1
 2 90
43 gudmap kidney e15.5 SmlBldVes Tie2 k1 1000 kidney e15.5 SmlBldVes Tie2 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 6.205E-4 2.049E-2
1.606E-1
8.811E-1
 2 92
44 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour PapRCC NK cell/Kidney Tumour PapRCC NK10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour PapRCC NK cell/Kidney Tumour PapRCC NK10 Adult, Development, and Cancer types 8.244E-4 2.491E-2
1.952E-1
1.000E0
 1 2
45 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-G/Kidney Tumour RCC EN-G/Kidney Tumour RCC EN6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-G/Kidney Tumour RCC EN-G/Kidney Tumour RCC EN6 Adult, Development, and Cancer types 8.244E-4 2.491E-2
1.952E-1
1.000E0
 1 2
46 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour RCC R U/Kidney Tumour RCC R6 Adult, Development, and Cancer types 8.244E-4 2.491E-2
1.952E-1
1.000E0
 1 2
47 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Th cell/Kidney Tumour Wilms Th cell/Kidney Tumour Wilms IT0 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Th cell/Kidney Tumour Wilms Th cell/Kidney Tumour Wilms IT0 Adult, Development, and Cancer types 8.244E-4 2.491E-2
1.952E-1
1.000E0
 1 2
48 PCBC ctl CardioEndothel 500 Progenitor-Cell-Biology-Consortium reference CardioEndothel top-relative-expression-ranked 500 PCBC 8.896E-4 2.554E-2
2.002E-1
1.000E0
 3 497
49 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK6 Adult, Development, and Cancer types 9.174E-4 2.554E-2
2.002E-1
1.000E0
 2 112
50 Sample Type by Project: Shred 1/TCGA-Prostate/Prostate Adenocarcinoma /Acinar Adenocarcinoma/4 Sample Type by Project: Shred 1/TCGA-Prostate/Prostate Adenocarcinoma /Acinar Adenocarcinoma/4 TCGA-Prostate 9.836E-4 2.554E-2
2.002E-1
1.000E0
 2 116
Show 45 more annotations

15: Computational [Display Chart] 8 input genes in category / 127 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M15983 MODULE 46 Genes in the cancer module 46. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.616E-6 5.862E-4 3.180E-3 5.862E-4 5 394
2 M12401 MODULE 75 Immune response. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.502E-4 9.535E-3
5.173E-2
 1.907E-2 4 398
3 M5587 GNF2 MMP1 Neighborhood of MMP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.725E-4 1.097E-2
5.952E-2
 3.460E-2 2 32
4 M11282 GNF2 PTX3 Neighborhood of PTX3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.455E-4 1.097E-2
5.952E-2
 4.388E-2 2 36
5 M7015 MODULE 263 Chemotaxis (chemokines). MSigDb: C4 - CM: Cancer Modules (v6.0) 5.410E-4 1.374E-2
7.455E-2
6.871E-2
 2 45
6 M6482 MODULE 108 Genes in the cancer module 108. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.379E-4 1.774E-2
9.622E-2
1.064E-1
 2 56
7 M17322 MODULE 76 Inflammatory response. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.745E-3 3.167E-2
1.718E-1
2.217E-1
 2 81
8 M11185 MODULE 128 Genes in the cancer module 128. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.543E-3 3.427E-2
1.859E-1
3.230E-1
 2 98
9 M8286 MODULE 79 Genes in the cancer module 79. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.646E-3 3.427E-2
1.859E-1
3.361E-1
 2 100
10 M2944 MODULE 170 Immune response. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.699E-3 3.427E-2
1.859E-1
3.427E-1
 2 101
11 M15763 MODULE 60 Heart genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.600E-3 3.733E-2
2.025E-1
4.572E-1
 3 425
12 M10190 MODULE 52 Cell line expressed genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.796E-3 3.733E-2
2.025E-1
4.821E-1
 3 433
13 M7383 MODULE 5 Lung genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.821E-3 3.733E-2
2.025E-1
4.853E-1
 3 434
Show 8 more annotations

16: MicroRNA [Display Chart] 9 input genes in category / 221 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-1296-5p:Functional MTI Functional MTI miRTarbase 9.776E-5 1.530E-2
9.147E-2
 2.160E-2 2 120
2 hsa-miR-518a-5p:Functional MTI Functional MTI miRTarbase 1.759E-4 1.530E-2
9.147E-2
 3.887E-2 2 161
3 hsa-miR-532-5p:TargetScan hsa-miR-532-5p TargetScan 2.077E-4 1.530E-2
9.147E-2
 4.591E-2 2 175
4 hsa-miR-769-5p:Non-Functional MTI Non-Functional MTI miRTarbase 3.549E-4 1.961E-2
1.172E-1
7.844E-2
 2 229
5 hsa-miR-4786-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.780E-4 2.113E-2
1.263E-1
1.056E-1
 2 266

17: Drug [Display Chart] 9 input genes in category / 4395 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ctd:D014107 Tosyllysine Chloromethyl Ketone CTD 1.943E-10 8.537E-7 7.654E-6 8.537E-7 4 27
2 ctd:D006221 Halothane CTD 1.236E-9 1.996E-6 1.789E-5 5.431E-6 4 42
3 ctd:D002809 Chondroitin Sulfates CTD 1.362E-9 1.996E-6 1.789E-5 5.987E-6 4 43
4 ctd:D017632 Asbestos, Serpentine CTD 4.766E-9 5.236E-6 4.694E-5 2.094E-5 6 454
5 ctd:C020972 pyrrolidine dithiocarbamic acid CTD 8.225E-9 7.229E-6 6.482E-5 3.615E-5 5 213
6 ctd:D011070 Poly I-C CTD 5.423E-8 3.972E-5 3.561E-4 2.383E-4 4 106
7 ctd:C056933 fumonisin B1 CTD 7.910E-8 4.966E-5 4.452E-4 3.476E-4 5 335
8 ctd:D004731 Endotoxins CTD 1.231E-7 6.014E-5 5.391E-4 5.412E-4 3 27
9 ctd:C499366 Active Hexose Correlated Compound CTD 1.231E-7 6.014E-5 5.391E-4 5.412E-4 3 27
10 ctd:D011112 Polymyxin B CTD 1.891E-7 8.311E-5 7.451E-4 8.311E-4 3 31
11 ctd:C000593591 coagulin-L CTD 2.516E-7 8.637E-5 7.743E-4 1.106E-3 3 34
12 ctd:D014051 Toluene 2,4-Diisocyanate CTD 2.703E-7 8.637E-5 7.743E-4 1.188E-3 4 158
13 ctd:C549066 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine CTD 2.751E-7 8.637E-5 7.743E-4 1.209E-3 3 35
14 ctd:D017997 Leukotriene C4 CTD 2.751E-7 8.637E-5 7.743E-4 1.209E-3 3 35
15 ctd:D002351 Carrageenan CTD 3.544E-7 1.038E-4 9.310E-4 1.558E-3 3 38
16 ctd:D007975 Leukotriene B4 CTD 3.838E-7 1.054E-4 9.453E-4 1.687E-3 3 39
17 ctd:C007262 deoxynivalenol CTD 4.866E-7 1.258E-4 1.128E-3 2.139E-3 5 483
18 CID000024586 nickel sulfate Stitch 7.227E-7 1.765E-4 1.582E-3 3.176E-3 4 202
19 ctd:D005620 Freund's Adjuvant CTD 8.123E-7 1.879E-4 1.685E-3 3.570E-3 4 208
20 ctd:C032628 tin protoporphyrin IX CTD 1.039E-6 2.283E-4 2.046E-3 4.565E-3 3 54
21 ctd:C044101 endotoxin, Escherichia coli CTD 1.098E-6 2.299E-4 2.061E-3 4.828E-3 3 55
22 ctd:D013458 Sulfur Dioxide CTD 1.291E-6 2.350E-4 2.107E-3 5.675E-3 3 58
23 ctd:D014013 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt CTD 1.291E-6 2.350E-4 2.107E-3 5.675E-3 3 58
24 ctd:D008055 Lipids CTD 1.360E-6 2.350E-4 2.107E-3 5.977E-3 3 59
25 ctd:C490266 neoechinulin A CTD 1.360E-6 2.350E-4 2.107E-3 5.977E-3 3 59
26 ctd:D004391 Dust CTD 1.390E-6 2.350E-4 2.107E-3 6.110E-3 4 238
27 ctd:D011765 Pyruvaldehyde CTD 1.741E-6 2.747E-4 2.463E-3 7.653E-3 3 64
28 ctd:D000171 Acrolein CTD 1.977E-6 2.747E-4 2.463E-3 8.687E-3 4 260
29 ctd:C501362 terutroban CTD 2.069E-6 2.747E-4 2.463E-3 9.091E-3 2 6
30 ctd:C042103 zinc nitrate CTD 2.069E-6 2.747E-4 2.463E-3 9.091E-3 2 6
31 ctd:D000451 Mineralocorticoid Receptor Antagonists CTD 2.069E-6 2.747E-4 2.463E-3 9.091E-3 2 6
32 ctd:D009183 Mycotoxins CTD 2.093E-6 2.747E-4 2.463E-3 9.198E-3 3 68
33 ctd:C038958 gadolinium chloride CTD 2.188E-6 2.747E-4 2.463E-3 9.615E-3 3 69
34 ctd:C005435 phenylmethylpyrazolone CTD 2.188E-6 2.747E-4 2.463E-3 9.615E-3 3 69
35 CID000009001 Tiron Stitch 2.188E-6 2.747E-4 2.463E-3 9.615E-3 3 69
36 ctd:D010431 Pentoxifylline CTD 2.285E-6 2.790E-4 2.501E-3 1.004E-2 3 70
37 ctd:D015112 4-Nitroquinoline-1-oxide CTD 2.385E-6 2.834E-4 2.540E-3 1.048E-2 3 71
38 CID000001606 NOC-18 Stitch 2.595E-6 2.892E-4 2.593E-3 1.140E-2 3 73
39 ctd:D014580 Ursodeoxycholic Acid CTD 2.654E-6 2.892E-4 2.593E-3 1.166E-2 4 280
40 ctd:C081643 candesartan CTD 2.704E-6 2.892E-4 2.593E-3 1.188E-2 3 74
41 CID005317757 AC1NSW03 Stitch 2.895E-6 2.892E-4 2.593E-3 1.272E-2 2 7
42 ctd:C528574 astressin-2B CTD 2.895E-6 2.892E-4 2.593E-3 1.272E-2 2 7
43 ctd:D017886 Durapatite CTD 2.895E-6 2.892E-4 2.593E-3 1.272E-2 2 7
44 CID000335426 isovalerylshikonin Stitch 2.895E-6 2.892E-4 2.593E-3 1.272E-2 2 7
45 CID000032744 polyinosinic-polycytidylic acid Stitch 3.092E-6 3.020E-4 2.708E-3 1.359E-2 4 291
46 ctd:D019819 Budesonide CTD 3.423E-6 3.270E-4 2.932E-3 1.504E-2 3 80
47 ctd:D005688 Galactosamine CTD 3.826E-6 3.326E-4 2.982E-3 1.681E-2 3 83
48 ctd:D010047 Ovalbumin CTD 3.826E-6 3.326E-4 2.982E-3 1.681E-2 3 83
49 ctd:C111520 ginsan CTD 3.860E-6 3.326E-4 2.982E-3 1.696E-2 2 8
50 CID000032465 D-mask Stitch 3.860E-6 3.326E-4 2.982E-3 1.696E-2 2 8
Show 45 more annotations

18: Disease [Display Chart] 9 input genes in category / 912 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0024115 Lung diseases DisGeNET Curated 5.285E-7 1.546E-4 1.143E-3 4.820E-4 5 349
2 C0014038 Encephalitis DisGeNET Curated 5.293E-7 1.546E-4 1.143E-3 4.827E-4 4 133
3 C0017668 Focal glomerulosclerosis DisGeNET Curated 5.789E-7 1.546E-4 1.143E-3 5.279E-4 4 136
4 C0524910 Hepatitis C, Chronic DisGeNET Curated 6.780E-7 1.546E-4 1.143E-3 6.183E-4 5 367
5 C0017152 Gastritis DisGeNET Curated 1.552E-6 2.142E-4 1.584E-3 1.415E-3 4 174
6 C1837174 HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS, FAMILIAL, 3 DisGeNET Curated 1.644E-6 2.142E-4 1.584E-3 1.500E-3 2 4
7 C0272199 Familial Hemophagocytic Lymphocytosis DisGeNET Curated 1.644E-6 2.142E-4 1.584E-3 1.500E-3 2 4
8 C1290886 Chronic inflammatory disorder DisGeNET BeFree 2.155E-6 2.456E-4 1.816E-3 1.965E-3 3 49
9 C0017661 IGA Glomerulonephritis DisGeNET Curated 3.739E-6 3.747E-4 2.770E-3 3.410E-3 4 217
10 C2931071 Dianzani autoimmune lymphoproliferative syndrome DisGeNET BeFree 4.108E-6 3.747E-4 2.770E-3 3.747E-3 2 6
11 C0042029 Urinary tract infection DisGeNET Curated 6.931E-6 5.366E-4 3.967E-3 6.321E-3 3 72
12 C0398686 Primary immune deficiency disorder DisGeNET BeFree 7.840E-6 5.366E-4 3.967E-3 7.150E-3 3 75
13 C1290398 Cerebral arterial aneurysm DisGeNET Curated 8.489E-6 5.366E-4 3.967E-3 7.742E-3 3 77
14 C0085655 Polymyositis DisGeNET Curated 8.826E-6 5.366E-4 3.967E-3 8.049E-3 3 78
15 C0025289 Meningitis DisGeNET Curated 8.826E-6 5.366E-4 3.967E-3 8.049E-3 3 78
16 C0221056 Adult type dermatomyositis DisGeNET BeFree 1.064E-5 5.489E-4 4.059E-3 9.708E-3 3 83
17 C3495559 Juvenile arthritis DisGeNET Curated 1.071E-5 5.489E-4 4.059E-3 9.766E-3 4 283
18 C0005411 Biliary Atresia DisGeNET Curated 1.104E-5 5.489E-4 4.059E-3 1.006E-2 3 84
19 C0035126 Reperfusion Injury DisGeNET Curated 1.144E-5 5.489E-4 4.059E-3 1.043E-2 3 85
20 C0877564 Lymphohistiocytosis DisGeNET BeFree 1.231E-5 5.614E-4 4.150E-3 1.123E-2 2 10
21 C1096155 Macrophage Activation Syndrome DisGeNET Curated 1.504E-5 5.980E-4 4.421E-3 1.372E-2 2 11
22 C0011633 Dermatomyositis DisGeNET Curated 1.548E-5 5.980E-4 4.421E-3 1.412E-2 3 94
23 C0374997 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site DisGeNET BeFree 1.574E-5 5.980E-4 4.421E-3 1.435E-2 4 312
24 C0850666 helicobacter pylori infection DisGeNET BeFree 1.574E-5 5.980E-4 4.421E-3 1.435E-2 4 312
25 C1318020 Stromal keratitis DisGeNET BeFree 1.804E-5 6.111E-4 4.518E-3 1.646E-2 2 12
26 C0018915 Hemangioendothelioma DisGeNET BeFree 1.804E-5 6.111E-4 4.518E-3 1.646E-2 2 12
27 C0162820 Dermatitis, Allergic Contact DisGeNET Curated 1.809E-5 6.111E-4 4.518E-3 1.650E-2 3 99
28 C0155686 Acute myocarditis DisGeNET BeFree 2.132E-5 6.944E-4 5.134E-3 1.944E-2 2 13
29 C0014070 Encephalomyelitis DisGeNET BeFree 2.392E-5 7.267E-4 5.373E-3 2.181E-2 4 347
30 C0027059 Myocarditis DisGeNET Curated 2.482E-5 7.267E-4 5.373E-3 2.263E-2 3 110
31 C0221376 Hydrosalpinx (disease) DisGeNET BeFree 2.487E-5 7.267E-4 5.373E-3 2.268E-2 2 14
32 C0020429 Hyperalgesia DisGeNET Curated 2.550E-5 7.267E-4 5.373E-3 2.325E-2 3 111
33 C0022661 Kidney Failure, Chronic DisGeNET Curated 2.733E-5 7.554E-4 5.585E-3 2.493E-2 4 359
34 C0039483 Giant Cell Arteritis DisGeNET Curated 3.141E-5 8.424E-4 6.228E-3 2.864E-2 3 119
35 C0031154 Peritonitis DisGeNET Curated 3.638E-5 9.480E-4 7.009E-3 3.318E-2 3 125
36 C0027697 Nephritis DisGeNET Curated 4.784E-5 1.212E-3 8.961E-3 4.363E-2 3 137
37 C0876991 Histiocytosis haematophagic DisGeNET Curated 5.183E-5 1.277E-3 9.445E-3 4.727E-2 2 20
38 C0152451 Chronic glomerulonephritis DisGeNET BeFree 6.298E-5 1.511E-3 1.117E-2
5.743E-2
 2 22
39 C0041327 Tuberculosis, Pulmonary DisGeNET Curated 7.456E-5 1.744E-3 1.289E-2
6.800E-2
 3 159
40 C0039263 Takayasu Arteritis DisGeNET Curated 8.172E-5 1.863E-3 1.377E-2
7.452E-2
 2 25
41 C0751633 Carotid Artery Plaque DisGeNET BeFree 8.850E-5 1.929E-3 1.426E-2
8.071E-2
 2 26
42 C0151517 Complete atrioventricular block DisGeNET Curated 8.938E-5 1.929E-3 1.426E-2
8.152E-2
 3 169
43 C0268731 Renal glomerular disease DisGeNET Curated 9.096E-5 1.929E-3 1.426E-2
8.296E-2
 3 170
44 C0206019 HIV Encephalopathy DisGeNET BeFree 9.555E-5 1.975E-3 1.460E-2
8.714E-2
 2 27
45 C0494165 Secondary malignant neoplasm of liver DisGeNET BeFree 9.743E-5 1.975E-3 1.460E-2
8.886E-2
 4 497
46 C1328840 Autoimmune Lymphoproliferative Syndrome DisGeNET Curated 1.105E-4 2.143E-3 1.585E-2
1.007E-1
 2 29
47 C0276548 HIV encephalitis DisGeNET BeFree 1.105E-4 2.143E-3 1.585E-2
1.007E-1
 2 29
48 C0086445 Idiopathic Membranous Glomerulonephritis DisGeNET BeFree 1.264E-4 2.402E-3 1.776E-2
1.153E-1
 2 31
49 C1384600 Systemic onset juvenile chronic arthritis DisGeNET Curated 1.348E-4 2.510E-3 1.855E-2
1.230E-1
 2 32
50 C0340629 Aortic aneurysm without mention of rupture NOS DisGeNET BeFree 1.435E-4 2.617E-3 1.935E-2
1.309E-1
 2 33
Show 45 more annotations