Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc225_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 8 annotations before applied cutoff / 18661 genes in category

No results to display

2: GO: Biological Process [Display Chart] 5 input genes in category / 86 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0046587 positive regulation of calcium-dependent cell-cell adhesion 2.685E-4 1.539E-2
7.753E-2
 2.309E-2 1 1
2 GO:0046586 regulation of calcium-dependent cell-cell adhesion 5.369E-4 1.539E-2
7.753E-2
 4.617E-2 1 2
3 GO:0048211 Golgi vesicle docking 5.369E-4 1.539E-2
7.753E-2
 4.617E-2 1 2
4 GO:0051650 establishment of vesicle localization 1.775E-3 2.307E-2
1.162E-1
1.527E-1
 2 252
5 GO:0072386 plus-end-directed organelle transport along microtubule 1.878E-3 2.307E-2
1.162E-1
1.615E-1
 1 7
6 GO:0072383 plus-end-directed vesicle transport along microtubule 1.878E-3 2.307E-2
1.162E-1
1.615E-1
 1 7
7 GO:0051648 vesicle localization 1.990E-3 2.307E-2
1.162E-1
1.712E-1
 2 267
8 GO:0048680 positive regulation of axon regeneration 2.414E-3 2.307E-2
1.162E-1
2.076E-1
 1 9
9 GO:0048280 vesicle fusion with Golgi apparatus 2.682E-3 2.307E-2
1.162E-1
2.307E-1
 1 10
10 GO:0070572 positive regulation of neuron projection regeneration 2.682E-3 2.307E-2
1.162E-1
2.307E-1
 1 10
11 GO:0048193 Golgi vesicle transport 3.205E-3 2.505E-2
1.262E-1
2.756E-1
 2 340
12 GO:0045056 transcytosis 4.289E-3 3.074E-2
1.548E-1
3.688E-1
 1 16
13 GO:0051656 establishment of organelle localization 5.265E-3 3.483E-2
1.755E-1
4.528E-1
 2 438
14 GO:0048679 regulation of axon regeneration 6.161E-3 3.784E-2
1.906E-1
5.298E-1
 1 23
15 GO:0070570 regulation of neuron projection regeneration 7.229E-3 4.145E-2
2.088E-1
6.217E-1
 1 27
Show 10 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 27 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016939 kinesin II complex 7.868E-4 2.124E-2
8.264E-2
 2.124E-2 1 3
2 GO:1990075 periciliary membrane compartment 1.573E-3 2.124E-2
8.264E-2
 4.247E-2 1 6
3 GO:0005874 microtubule 4.765E-3 4.223E-2
1.643E-1
1.287E-1
 2 426
4 GO:0030990 intraciliary transport particle 8.367E-3 4.223E-2
1.643E-1
2.259E-1
 1 32
5 GO:0032391 photoreceptor connecting cilium 1.045E-2 4.223E-2
1.643E-1
2.821E-1
 1 40
6 GO:0097542 ciliary tip 1.175E-2 4.223E-2
1.643E-1
3.172E-1
 1 45
7 GO:0001917 photoreceptor inner segment 1.201E-2 4.223E-2
1.643E-1
3.243E-1
 1 46
8 GO:0012507 ER to Golgi transport vesicle membrane 1.435E-2 4.223E-2
1.643E-1
3.873E-1
 1 55
9 GO:0005871 kinesin complex 1.435E-2 4.223E-2
1.643E-1
3.873E-1
 1 55
10 GO:0005876 spindle microtubule 1.564E-2 4.223E-2
1.643E-1
4.223E-1
 1 60
11 GO:0030134 COPII-coated ER to Golgi transport vesicle 1.849E-2 4.538E-2
1.766E-1
4.992E-1
 1 71
12 GO:0000794 condensed nuclear chromosome 2.519E-2 4.673E-2
1.818E-1
6.801E-1
 1 97
13 GO:0097014 ciliary plasm 2.570E-2 4.673E-2
1.818E-1
6.940E-1
 1 99
14 GO:0005930 axoneme 2.570E-2 4.673E-2
1.818E-1
6.940E-1
 1 99
15 GO:0036064 ciliary basal body 2.596E-2 4.673E-2
1.818E-1
7.009E-1
 1 100
Show 10 more annotations

4: Human Phenotype [Display Chart] 0 input genes in category / 0 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 5 input genes in category / 158 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 5 input genes in category / 43 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS50176 ARM REPEAT PROSITE 4.427E-5 8.787E-4 3.822E-3 1.903E-3 2 40
2 SM00185 ARM SMART 4.427E-5 8.787E-4 3.822E-3 1.903E-3 2 40
3 IPR000225 Armadillo InterPro 6.130E-5 8.787E-4 3.822E-3 2.636E-3 2 47
4 IPR008658 KAP3 InterPro 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
5 IPR024095 Vesicle P115-like InterPro 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
6 IPR006955 Uso1 p115 C InterPro 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
7 IPR033623 RASSF5 InterPro 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
8 IPR006953 Vesicle Uso1 P115 head InterPro 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
9 IPR028869 RRAD InterPro 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
10 PF04871 Uso1 p115 C Pfam 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
11 PF04869 Uso1 p115 head Pfam 2.669E-4 1.043E-3 4.538E-3 1.148E-2 1 1
12 IPR017358 Small GTPase GEM/REM/Rad InterPro 1.067E-3 3.824E-3 1.663E-2 4.589E-2 1 4
13 IPR033614 C-RASSF InterPro 1.600E-3 4.916E-3 2.138E-2
6.882E-2
 1 6
14 PF16517 Nore1-SARAH Pfam 1.600E-3 4.916E-3 2.138E-2
6.882E-2
 1 6
15 PS50951 SARAH PROSITE 2.400E-3 6.450E-3 2.806E-2
1.032E-1
 1 9
16 IPR011524 SARAH dom InterPro 2.400E-3 6.450E-3 2.806E-2
1.032E-1
 1 9
17 IPR016024 ARM-type fold InterPro 3.167E-3 8.011E-3 3.485E-2
1.362E-1
 2 340
18 SM00314 RA SMART 8.247E-3 1.923E-2
8.363E-2
3.546E-1
 1 31
19 PS51421 RAS PROSITE 9.307E-3 1.923E-2
8.363E-2
4.002E-1
 1 35
20 PF00788 RA Pfam 9.572E-3 1.923E-2
8.363E-2
4.116E-1
 1 36
21 PS50200 RA PROSITE 9.837E-3 1.923E-2
8.363E-2
4.230E-1
 1 37
22 IPR020849 Small GTPase Ras InterPro 9.837E-3 1.923E-2
8.363E-2
4.230E-1
 1 37
23 IPR000159 RA dom InterPro 1.063E-2 1.988E-2
8.646E-2
4.571E-1
 1 40
24 PF00130 C1 1 Pfam 1.512E-2 2.686E-2
1.169E-1
6.502E-1
 1 57
25 PS00479 ZF DAG PE 1 PROSITE 1.697E-2 2.686E-2
1.169E-1
7.295E-1
 1 64
26 PS50081 ZF DAG PE 2 PROSITE 1.697E-2 2.686E-2
1.169E-1
7.295E-1
 1 64
27 SM00109 C1 SMART 1.723E-2 2.686E-2
1.169E-1
7.409E-1
 1 65
28 IPR002219 PE/DAG-bd InterPro 1.749E-2 2.686E-2
1.169E-1
7.522E-1
 1 66
Show 23 more annotations

7: Pathway [Display Chart] 4 input genes in category / 30 annotations before applied cutoff / 12450 genes in category

No results to display

8: Pubmed [Display Chart] 5 input genes in category / 251 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 22750872 Expression, purification, crystallization and preliminary X-ray analysis of the human NORE1 SARAH domain. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
2 22487779 Promoter hypermethylation of Ras-related GTPase gene RRAD inactivates a tumor suppressor function in nasopharyngeal carcinoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
3 8798502 Overexpression of Rad inhibits glucose uptake in cultured muscle and fat cells. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
4 17113389 A role for kinesin-2 in COPI-dependent recycling between the ER and the Golgi complex. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
5 25456499 MST3 kinase phosphorylates TAO1/2 to enable Myosin Va function in promoting spine synapse development. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
6 23750925 Kinesin-2: a family of heterotrimeric and homodimeric motors with diverse intracellular transport functions. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
7 12676952 The pro-apoptotic Ras effector Nore1 may serve as a Ras-regulated tumor suppressor in the lung. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
8 20339001 Growth and tumor suppressor NORE1A is a regulatory node between Ras signaling and microtubule nucleation. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
9 19028683 Nuclear import is required for the pro-apoptotic function of the Golgi protein p115. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
10 20079427 Oxidative stress in skeletal muscle stimulates early expression of Rad in a mouse model of amyotrophic lateral sclerosis. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
11 25109282 RASSF5 inhibits growth and invasion and induces apoptosis in osteosarcoma cells through activation of MST1/LATS1 signaling. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
12 7859947 Trinucleotide repeats at the rad locus. Allele distributions in NIDDM and mapping to a 3-cM region on chromosome 16q. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
13 18452173 Assessment of NORE1A as a putative tumor suppressor in human neuroblastoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
14 16757334 RASSF family proteins and Ras transformation. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
15 24838185 Analysis of the KIFAP3 gene in amyotrophic lateral sclerosis: a multicenter survival study. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
16 17046825 Inhibition of cell migration by autophosphorylated mammalian sterile 20-like kinase 3 (MST3) involves paxillin and protein-tyrosine phosphatase-PEST. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
17 17195088 Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
18 28140676 Further analysis of KIFAP3 gene in ALS patients from Switzerland and Sweden. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
19 27798760 Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
20 21277991 Mammalian Ste20-like protein kinase 3 plays a role in hypoxia-induced apoptosis of trophoblast cell line 3A-sub-E. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
21 20434789 Suppression of hydroxyurea-induced centrosome amplification by NORE1A and down-regulation of NORE1A mRNA expression in non-small cell lung carcinoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
22 24222170 Aberrant methylation of the Ras-related associated with diabetes gene in human primary esophageal cancer. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
23 19782762 Mammalian Ste20-like protein kinase 3 induces a caspase-independent apoptotic pathway. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
24 28732776 Rad GTPase is essential for the regulation of bone density and bone marrow adipose tissue in mice. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
25 10644707 Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
26 16256943 Depletion of vesicle-tethering factor p115 causes mini-stacked Golgi fragments with delayed protein transport. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
27 1512287 A novel 115-kD peripheral membrane protein is required for intercisternal transport in the Golgi stack. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
28 15304321 Identification and characterization of the nuclear import and export signals of the mammalian Ste20-like protein kinase 3. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
29 18040775 Mammalian Ste20-like protein kinase 3 mediates trophoblast apoptosis in spontaneous delivery. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
30 14736916 Gene replacement reveals that p115/SNARE interactions are essential for Golgi biogenesis. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
31 28956081 The MST3/STK24 kinase mediates impaired fasting blood glucose after a high-fat diet. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
32 26546438 RRAD inhibits aerobic glycolysis, invasion, and migration and is associated with poor prognosis in hepatocellular carcinoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
33 8710890 Cloning and characterization of KAP3: a novel kinesin superfamily-associated protein of KIF3A/3B. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
34 22229648 A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3). Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
35 24334906 Rad GTPase deletion increases L-type calcium channel current leading to increased cardiac contraction. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
36 21659726 Genetic variation in KIFAP3 is associated with an upper motor neuron-predominant phenotype in amyotrophic lateral sclerosis. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
37 16421102 The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
38 15979508 Golgins and GTPases, giving identity and structure to the Golgi apparatus. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
39 22658652 Rad knockdown induces mitochondrial apoptosis in bortezomib resistant leukemia and lymphoma cells. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
40 25420558 Decreased expression and aberrant methylation of RASSF5A correlates with malignant progression of gastric cardia adenocarcinoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
41 21536679 The Golgi protein p115 associates with gamma-tubulin and plays a role in Golgi structure and mitosis progression. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
42 9786945 The membrane transport factor TAP/p115 cycles between the Golgi and earlier secretory compartments and contains distinct domains required for its localization and function. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
43 26184508 Lentivirus-mediated silencing of USO1 inhibits cell proliferation and migration of human colon cancer cells. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
44 10793158 Involvement of a small GTP-binding protein (G protein) regulator, small G protein GDP dissociation stimulator, in antiapoptotic cell survival signaling. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
45 16511212 Expression, purification, crystallization and preliminary crystallographic analysis of human Rad GTPase. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
46 16221735 Rad is temporally regulated within myogenic progenitor cells during skeletal muscle regeneration. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
47 19247479 Unusual armadillo fold in the human general vesicular transport factor p115. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
48 16537411 Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
49 16516329 NORE1B, a candidate tumor suppressor, is epigenetically silenced in human hepatocellular carcinoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
50 25579665 RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma. Pubmed 1.309E-4 4.564E-4 2.786E-3 3.286E-2 1 1
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 280 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:EEA1 EEA1 interactions 7.162E-5 1.368E-2
8.498E-2
 2.005E-2 2 48
2 int:RAP2A RAP2A interactions 9.769E-5 1.368E-2
8.498E-2
 2.735E-2 2 56
3 int:CEP19 CEP19 interactions 3.444E-4 3.215E-2
1.997E-1
9.644E-2
 2 105
4 int:VCL VCL interactions 4.956E-4 3.469E-2
2.156E-1
1.388E-1
 2 126
5 int:GTSE1 GTSE1 interactions 6.737E-4 3.590E-2
2.231E-1
1.886E-1
 2 147
6 int:CCDC168 CCDC168 interactions 8.471E-4 3.590E-2
2.231E-1
2.372E-1
 1 3
7 int:CASP8 CASP8 interactions 1.030E-3 3.590E-2
2.231E-1
2.884E-1
 2 182
8 int:CASP3 CASP3 interactions 1.053E-3 3.590E-2
2.231E-1
2.947E-1
 2 184
9 int:SETD9 SETD9 interactions 1.412E-3 3.590E-2
2.231E-1
3.952E-1
 1 5
10 int:JPH3 JPH3 interactions 1.412E-3 3.590E-2
2.231E-1
3.952E-1
 1 5
11 int:ZNF821 ZNF821 interactions 1.976E-3 3.590E-2
2.231E-1
5.532E-1
 1 7
12 int:PHYKPL PHYKPL interactions 1.976E-3 3.590E-2
2.231E-1
5.532E-1
 1 7
13 int:C4orf19 C4orf19 interactions 2.258E-3 3.590E-2
2.231E-1
6.322E-1
 1 8
14 int:PRKACA PRKACA interactions 2.467E-3 3.590E-2
2.231E-1
6.907E-1
 2 283
15 int:ADH6 ADH6 interactions 2.540E-3 3.590E-2
2.231E-1
7.111E-1
 1 9
16 int:CSNK2B CSNK2B interactions 2.785E-3 3.590E-2
2.231E-1
7.799E-1
 2 301
17 int:SLCO1B1 SLCO1B1 interactions 2.822E-3 3.590E-2
2.231E-1
7.900E-1
 1 10
18 int:CEP68 CEP68 interactions 3.103E-3 3.590E-2
2.231E-1
8.689E-1
 1 11
19 int:BET1L BET1L interactions 3.385E-3 3.590E-2
2.231E-1
9.478E-1
 1 12
20 int:MRPS17 MRPS17 interactions 3.667E-3 3.590E-2
2.231E-1
1.000E0
 1 13
21 int:MUC13 MUC13 interactions 3.667E-3 3.590E-2
2.231E-1
1.000E0
 1 13
22 int:KIF3C KIF3C interactions 3.667E-3 3.590E-2
2.231E-1
1.000E0
 1 13
23 int:TSNAXIP1 TSNAXIP1 interactions 3.667E-3 3.590E-2
2.231E-1
1.000E0
 1 13
24 int:RRAD RRAD interactions 4.230E-3 3.590E-2
2.231E-1
1.000E0
 1 15
25 int:SEMA4F SEMA4F interactions 4.230E-3 3.590E-2
2.231E-1
1.000E0
 1 15
26 int:FAM184A FAM184A interactions 4.230E-3 3.590E-2
2.231E-1
1.000E0
 1 15
27 int:CRYBG1 CRYBG1 interactions 4.230E-3 3.590E-2
2.231E-1
1.000E0
 1 15
28 int:MRAS MRAS interactions 4.511E-3 3.590E-2
2.231E-1
1.000E0
 1 16
29 int:ZNF488 ZNF488 interactions 4.511E-3 3.590E-2
2.231E-1
1.000E0
 1 16
30 int:SCPEP1 SCPEP1 interactions 5.355E-3 3.590E-2
2.231E-1
1.000E0
 1 19
31 int:SEC22A SEC22A interactions 5.355E-3 3.590E-2
2.231E-1
1.000E0
 1 19
32 int:RUSC2 RUSC2 interactions 5.355E-3 3.590E-2
2.231E-1
1.000E0
 1 19
33 int:STRIP2 STRIP2 interactions 5.637E-3 3.590E-2
2.231E-1
1.000E0
 1 20
34 int:CCSER2 CCSER2 interactions 5.637E-3 3.590E-2
2.231E-1
1.000E0
 1 20
35 int:CCNY CCNY interactions 5.637E-3 3.590E-2
2.231E-1
1.000E0
 1 20
36 int:ERICH5 ERICH5 interactions 5.918E-3 3.590E-2
2.231E-1
1.000E0
 1 21
37 int:MEST MEST interactions 5.918E-3 3.590E-2
2.231E-1
1.000E0
 1 21
38 int:OSBPL1A OSBPL1A interactions 5.918E-3 3.590E-2
2.231E-1
1.000E0
 1 21
39 int:S100A13 S100A13 interactions 5.918E-3 3.590E-2
2.231E-1
1.000E0
 1 21
40 int:RAP2B RAP2B interactions 6.199E-3 3.590E-2
2.231E-1
1.000E0
 1 22
41 int:TRIP11 TRIP11 interactions 6.480E-3 3.590E-2
2.231E-1
1.000E0
 1 23
42 int:HIPK1 HIPK1 interactions 6.480E-3 3.590E-2
2.231E-1
1.000E0
 1 23
43 int:MAGIX MAGIX interactions 6.761E-3 3.590E-2
2.231E-1
1.000E0
 1 24
44 int:ATP6V1C2 ATP6V1C2 interactions 7.042E-3 3.590E-2
2.231E-1
1.000E0
 1 25
45 int:MDM2 MDM2 interactions 7.233E-3 3.590E-2
2.231E-1
1.000E0
 2 490
46 int:PRCP PRCP interactions 7.323E-3 3.590E-2
2.231E-1
1.000E0
 1 26
47 int:NCF2 NCF2 interactions 7.603E-3 3.590E-2
2.231E-1
1.000E0
 1 27
48 int:GOSR2 GOSR2 interactions 7.603E-3 3.590E-2
2.231E-1
1.000E0
 1 27
49 int:BUD13 BUD13 interactions 7.603E-3 3.590E-2
2.231E-1
1.000E0
 1 27
50 int:PARD6G PARD6G interactions 7.603E-3 3.590E-2
2.231E-1
1.000E0
 1 27
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 13q31.2-q32.3 13q31.2-q32.3 1.443E-4 7.213E-4 1.647E-3 7.213E-4 1 1
2 16q22 16q22 2.594E-3 6.485E-3 1.481E-2 1.297E-2 1 18
3 1q24.2 1q24.2 4.464E-3 6.837E-3 1.561E-2 2.232E-2 1 31
4 4q21.1 4q21.1 5.470E-3 6.837E-3 1.561E-2 2.735E-2 1 38
5 1q32.1 1q32.1 1.634E-2 1.634E-2 3.731E-2
8.169E-2
 1 114

11: Transcription Factor Binding Site [Display Chart] 4 input genes in category / 20 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 3 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1260 RGK type GTPase family genenames.org 6.594E-4 1.978E-3 3.627E-3 1.978E-3 1 4
2 1198 Ras association domain family genenames.org 1.648E-3 2.472E-3 4.532E-3 4.944E-3 1 10
3 1371 STRIPAK complex genenames.org 3.294E-3 3.294E-3 6.040E-3 9.883E-3 1 20

13: Coexpression [Display Chart] 5 input genes in category / 652 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M1666 Strongly down-regulated at 8-96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.552E-4 2.647E-2
1.869E-1
1.012E-1
 2 92
2 16707426-SuppTable2 Human Prostate Zhang06 128genes GeneSigDB 2.729E-4 2.647E-2
1.869E-1
1.779E-1
 2 122
3 M5853 Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] versus untreated monocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 2.647E-2
1.869E-1
4.718E-1
 2 199
4 M5879 Genes down-regulated in comparison of monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist) versus untreated monocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 2.647E-2
1.869E-1
4.718E-1
 2 199
5 M9439 Genes up-regulated in normal T reg (nTreg): FOXO1 [GeneID=2308] versus wildtype. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
6 M5742 Genes down-regulated in comparison of lymph node regulatory T cells versus fat tissue regulatory T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
7 M8569 Genes up-regulated in Th1 cells 15 days post polarization: control versus stimulated with anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
8 M9023 Genes up-regulated in CD69- KRLG1- [GeneID=969;10219] T reg: SELL high [GeneID=6402] versus SELL low [GeneID=6402]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
9 M7136 Genes down-regulated in CD8A- [GeneID=925] splenic dendritic cells: IFNAR1 [GeneID=3454] knockout versus IFNB1 [GeneID=3456] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
10 M8528 Genes up-regulated in macrophages: alternatively activated M2 versus MYC [GeneID=4609] inhibited. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
11 M3817 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 12 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
12 M3636 Genes up-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after treatment with trichostatin A (TSA) [PubChem=5562]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
13 M7053 Genes up-regulated in megakaryo-erythrocyte progenitors versus pro-B lymphocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
14 M7742 Genes up-regulated in macrophages: wildtype versus NR3C2 [GeneID=4306] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
15 M3510 Genes down-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
16 M5677 Genes up-regulated in comparsion of ActCD8 versus ActCD8TGF (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
17 M4763 Genes up-regulated in comparison of LSK versus monocyte macrophages. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
18 M7028 Genes down-regulated in granulo-monocyte progenitors: wildtype versus IKZF1 [GeneID=10320] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.647E-2
1.869E-1
4.765E-1
 2 200
19 15466185-Table3 Human StemCell Upender04 10genes GeneSigDB 1.512E-3 4.868E-2
3.436E-1
9.858E-1
 1 7
20 16705090-TableS2 Human Leukemia Walker06 341genes GeneSigDB 1.709E-3 4.868E-2
3.436E-1
1.000E0
 2 307
21 M2351 Genes down-regulated in leukemic progenitor cells expressing activated fusion of ESWR1 and FLI1 [GeneID=2130, 2313] compared to normal hematopoetic progenitors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.867E-3 4.868E-2
3.436E-1
1.000E0
 2 321
22 M11031 Genes specifically up-regulated in pediatric acute lymphoblastic leukemia (ALL) patients by mercaptopurine [PubChem=667490] and low-dose methotrexate (LDMTX) [PubChem=4112]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.159E-3 4.868E-2
3.436E-1
1.000E0
 1 10
23 20054351-Table3 Human MultipleMyeloma Gutierrez10 12genes GeneSigDB 2.591E-3 4.868E-2
3.436E-1
1.000E0
 1 12
24 M1207 Genes within amplicon 1q32 identified in a copy number alterations study of 191 breast tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.806E-3 4.868E-2
3.436E-1
1.000E0
 1 13
25 19096012-TableS2 Human Viral Chetaille09 501genes GeneSigDB 3.458E-3 4.868E-2
3.436E-1
1.000E0
 2 439
26 12829800-IntrinsicList Human Breast Sorlie03 552genes IntrinsicGeneList GeneSigDB 3.710E-3 4.868E-2
3.436E-1
1.000E0
 2 455
27 19204204-SupplementaryTable9 Human Breast Parker09 500genes IntrinsicGenes SorlieAnnot GeneSigDB 3.742E-3 4.868E-2
3.436E-1
1.000E0
 2 457
28 17313671-SuppTable1c Human Leukemia Li07 18genes GeneSigDB 3.884E-3 4.868E-2
3.436E-1
1.000E0
 1 18
29 15148361-Table1 Mouse Liver Tanaka04 36genes GeneSigDB 3.884E-3 4.868E-2
3.436E-1
1.000E0
 1 18
30 19525976-Table1b Human Lung Chitale09 25genes KRAS GeneSigDB 4.315E-3 4.868E-2
3.436E-1
1.000E0
 1 20
31 17428335-tableS5d Human Breast Korkola07 22genes-OverlapGenes GeneSigDB 4.530E-3 4.868E-2
3.436E-1
1.000E0
 1 21
32 15482854-Table3 Human Immune Sillanp04 24genes GeneSigDB 4.961E-3 4.868E-2
3.436E-1
1.000E0
 1 23
33 17675577-Table2 Human Hyperglycemia Qi07 25genes GeneSigDB 4.961E-3 4.868E-2
3.436E-1
1.000E0
 1 23
34 12163391-Table2 Human Brain Watson02 24genes GeneSigDB 5.176E-3 4.868E-2
3.436E-1
1.000E0
 1 24
35 20054351-Table4 Human MultipleMyeloma Gutierrez10 29genes GeneSigDB 5.176E-3 4.868E-2
3.436E-1
1.000E0
 1 24
36 M7048 Selected genes up-regulated in WS1 (fibroblast) in response to irradiation with high dose UV-C. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.391E-3 4.868E-2
3.436E-1
1.000E0
 1 25
37 M18213 Genes down-regulated in Barrett's esophagus compared to the normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.391E-3 4.868E-2
3.436E-1
1.000E0
 1 25
38 M2658 Genes from cluster 3: up-regulated in group D of tumors arising from overexpression of BCL2L1 and MYC [GeneID=598;4609] in plasma cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.822E-3 4.868E-2
3.436E-1
1.000E0
 1 27
39 15377468-Table3 Human Leukemia Lindvall04 30genes HigherExpression GeneSigDB 6.252E-3 4.868E-2
3.436E-1
1.000E0
 1 29
40 M1452 Genes down-regulated in RAW 264.7 cells (macrophage) 3 hr after stimulation with bacterial lipopolysaccharide (LPS). MSigDB C2: CGP Curated Gene Sets (v6.0) 6.897E-3 4.868E-2
3.436E-1
1.000E0
 1 32
41 14695345-Table1a Mouse Viral Politi04 40genes UpRegulated GeneSigDB 6.897E-3 4.868E-2
3.436E-1
1.000E0
 1 32
42 19658189-TableS9a Human EmbryonicStemCell Xu09 34genes GeneSigDB 7.112E-3 4.868E-2
3.436E-1
1.000E0
 1 33
43 12640676-Table3 Mouse Skin Schlingemann03 46 GeneSigDB 7.112E-3 4.868E-2
3.436E-1
1.000E0
 1 33
44 18676871-Table2 Rat Esophagus Stoner08 53genes GeneSigDB 7.327E-3 4.868E-2
3.436E-1
1.000E0
 1 34
45 20054351-TableS2 Human MultipleMyeloma Gutierrez10 37genes GeneSigDB 7.327E-3 4.868E-2
3.436E-1
1.000E0
 1 34
46 16951165-Table2 Mouse Breast Hulit06 37genes GeneSigDB 7.327E-3 4.868E-2
3.436E-1
1.000E0
 1 34
47 15705876-TableS1 Human Leukemia Passioura05 36genes GeneSigDB 7.541E-3 4.868E-2
3.436E-1
1.000E0
 1 35
48 18281482-Table1 Human Colon Yokoe08 38genes GeneSigDB 7.756E-3 4.868E-2
3.436E-1
1.000E0
 1 36
49 M12210 Genes up-regulated in both colorectal cancer cells and normal testis relative to normal colon epithelium. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.186E-3 4.868E-2
3.436E-1
1.000E0
 1 38
50 M202 Genes up-regulated in hepatocellular carcinoma (HCC) samples from patients with early recurrence (within 2 years after surgery) after resection. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.400E-3 4.868E-2
3.436E-1
1.000E0
 1 39
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 373 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 2 input genes in category / 18 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 5 input genes in category / 117 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 TAATAAT,MIR-126:MSigDB TAATAAT,MIR-126:MSigDB MSigDB 7.969E-5 4.732E-3 2.528E-2 9.323E-3 2 205
2 hsa-miR-532-5p:PITA hsa-miR-532-5p:PITA TOP PITA 9.428E-5 4.732E-3 2.528E-2 1.103E-2 2 223
3 hsa-miR-1179:PITA hsa-miR-1179:PITA TOP PITA 1.213E-4 4.732E-3 2.528E-2 1.419E-2 2 253
4 hsa-miR-197-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.162E-4 9.248E-3 4.942E-2 3.699E-2 2 409
5 hsa-miR-671-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.038E-3 2.428E-2
1.298E-1
1.214E-1
 1 15
6 hsa-miR-6892-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.904E-3 3.047E-2
1.628E-1
3.397E-1
 1 42
7 hsa-miR-4475:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.870E-3 3.047E-2
1.628E-1
4.528E-1
 1 56
8 ACATATC,MIR-190:MSigDB ACATATC,MIR-190:MSigDB MSigDB 3.939E-3 3.047E-2
1.628E-1
4.609E-1
 1 57
9 hsa-miR-4454:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.008E-3 3.047E-2
1.628E-1
4.689E-1
 1 58
10 GTGTCAA,MIR-514:MSigDB GTGTCAA,MIR-514:MSigDB MSigDB 4.077E-3 3.047E-2
1.628E-1
4.770E-1
 1 59
11 CTAGGAA,MIR-384:MSigDB CTAGGAA,MIR-384:MSigDB MSigDB 4.146E-3 3.047E-2
1.628E-1
4.851E-1
 1 60
12 hsa-miR-4450:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.491E-3 3.047E-2
1.628E-1
5.254E-1
 1 65
13 hsa-miR-129-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.629E-3 3.047E-2
1.628E-1
5.416E-1
 1 67
14 hsa-miR-129-2-3p:Functional MTI Functional MTI miRTarbase 4.905E-3 3.047E-2
1.628E-1
5.738E-1
 1 71
15 ACACTCC,MIR-122A:MSigDB ACACTCC,MIR-122A:MSigDB MSigDB 5.042E-3 3.047E-2
1.628E-1
5.900E-1
 1 73
16 hsa-miR-6854-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.732E-3 3.047E-2
1.628E-1
6.706E-1
 1 83
17 hsa-miR-193a-5p:PITA hsa-miR-193a-5p:PITA TOP PITA 6.420E-3 3.047E-2
1.628E-1
7.512E-1
 1 93
18 hsa-miR-6782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.558E-3 3.047E-2
1.628E-1
7.673E-1
 1 95
19 hsa-miR-181c*:mirSVR highEffct hsa-miR-181c*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.627E-3 3.047E-2
1.628E-1
7.754E-1
 1 96
20 hsa-miR-7845-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.765E-3 3.047E-2
1.628E-1
7.915E-1
 1 98
21 hsa-miR-140-5p:Functional MTI Functional MTI miRTarbase 6.971E-3 3.047E-2
1.628E-1
8.156E-1
 1 101
22 hsa-miR-106b*:mirSVR highEffct hsa-miR-106b*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 7.040E-3 3.047E-2
1.628E-1
8.237E-1
 1 102
23 hsa-miR-6857-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.040E-3 3.047E-2
1.628E-1
8.237E-1
 1 102
24 hsa-miR-1308:PITA hsa-miR-1308:PITA TOP PITA 7.246E-3 3.047E-2
1.628E-1
8.478E-1
 1 105
25 hsa-miR-423-5p:PITA hsa-miR-423-5p:PITA TOP PITA 8.141E-3 3.047E-2
1.628E-1
9.525E-1
 1 118
26 hsa-miR-29b-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.209E-3 3.047E-2
1.628E-1
9.605E-1
 1 119
27 hsa-miR-3925-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.172E-3 3.047E-2
1.628E-1
1.000E0
 1 133
28 hsa-miR-425-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.927E-3 3.047E-2
1.628E-1
1.000E0
 1 144
29 hsa-miR-181a*:mirSVR highEffct hsa-miR-181a*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.013E-2 3.047E-2
1.628E-1
1.000E0
 1 147
30 hsa-miR-578:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.034E-2 3.047E-2
1.628E-1
1.000E0
 1 150
31 hsa-miR-197:PITA hsa-miR-197:PITA TOP PITA 1.048E-2 3.047E-2
1.628E-1
1.000E0
 1 152
32 hsa-miR-190:PITA hsa-miR-190:PITA TOP PITA 1.082E-2 3.047E-2
1.628E-1
1.000E0
 1 157
33 hsa-miR-190b:PITA hsa-miR-190b:PITA TOP PITA 1.082E-2 3.047E-2
1.628E-1
1.000E0
 1 157
34 hsa-miR-122-5p:TargetScan hsa-miR-122-5p TargetScan 1.151E-2 3.047E-2
1.628E-1
1.000E0
 1 167
35 hsa-miR-491-5p:Functional MTI Functional MTI miRTarbase 1.185E-2 3.047E-2
1.628E-1
1.000E0
 1 172
36 hsa-miR-3149:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.192E-2 3.047E-2
1.628E-1
1.000E0
 1 173
37 hsa-miR-514:PITA hsa-miR-514:PITA TOP PITA 1.205E-2 3.047E-2
1.628E-1
1.000E0
 1 175
38 hsa-miR-532-5p:TargetScan hsa-miR-532-5p TargetScan 1.205E-2 3.047E-2
1.628E-1
1.000E0
 1 175
39 hsa-miR-4735-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.240E-2 3.047E-2
1.628E-1
1.000E0
 1 180
40 hsa-miR-1257:PITA hsa-miR-1257:PITA TOP PITA 1.247E-2 3.047E-2
1.628E-1
1.000E0
 1 181
41 hsa-miR-765:PITA hsa-miR-765:PITA TOP PITA 1.260E-2 3.047E-2
1.628E-1
1.000E0
 1 183
42 hsa-miR-584:PITA hsa-miR-584:PITA TOP PITA 1.274E-2 3.047E-2
1.628E-1
1.000E0
 1 185
43 hsa-miR-214-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.294E-2 3.047E-2
1.628E-1
1.000E0
 1 188
44 hsa-miR-18a:PITA hsa-miR-18a:PITA TOP PITA 1.308E-2 3.047E-2
1.628E-1
1.000E0
 1 190
45 hsa-miR-18b:PITA hsa-miR-18b:PITA TOP PITA 1.308E-2 3.047E-2
1.628E-1
1.000E0
 1 190
46 ATGCTGC,MIR-103:MSigDB ATGCTGC,MIR-103:MSigDB MSigDB 1.397E-2 3.047E-2
1.628E-1
1.000E0
 1 203
47 ATGCTGC,MIR-107:MSigDB ATGCTGC,MIR-107:MSigDB MSigDB 1.397E-2 3.047E-2
1.628E-1
1.000E0
 1 203
48 hsa-miR-500b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.418E-2 3.047E-2
1.628E-1
1.000E0
 1 206
49 hsa-miR-193b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.479E-2 3.047E-2
1.628E-1
1.000E0
 1 215
50 hsa-miR-411-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.479E-2 3.047E-2
1.628E-1
1.000E0
 1 215
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 938 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000255720 3-methoxyanthranilate Stitch 2.189E-4 4.509E-2
3.346E-1
2.053E-1
 1 1
2 CID003828172 Big Chap Stitch 6.566E-4 4.509E-2
3.346E-1
6.159E-1
 1 3
3 CID000087251 methanesulfinic acid Stitch 6.566E-4 4.509E-2
3.346E-1
6.159E-1
 1 3
4 4690 DN Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 6.985E-4 4.509E-2
3.346E-1
6.552E-1
 2 193
5 2085 UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.130E-4 4.509E-2
3.346E-1
6.688E-1
 2 195
6 1379 UP Nalbuphine hydrochloride [23277-43-2]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 7.203E-4 4.509E-2
3.346E-1
6.756E-1
 2 196
7 7277 UP Azapropazone [13539-59-8]; Up 200; 13.4uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.276E-4 4.509E-2
3.346E-1
6.825E-1
 2 197
8 3017 UP Paromomycin sulfate [1263-89-4]; Up 200; 5.6uM; HL60; HT HG-U133A Broad Institute CMAP Up 7.349E-4 4.509E-2
3.346E-1
6.894E-1
 2 198
9 1994 UP Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 7.423E-4 4.509E-2
3.346E-1
6.963E-1
 2 199
10 3773 UP PHA-00851261E [724719-49-7]; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.498E-4 4.509E-2
3.346E-1
7.033E-1
 2 200
11 CID000124292 VDPs Stitch 8.754E-4 4.509E-2
3.346E-1
8.211E-1
 1 4
12 CID011971941 sy10 Stitch 8.754E-4 4.509E-2
3.346E-1
8.211E-1
 1 4
13 CID003080969 Med-27 Stitch 1.094E-3 4.509E-2
3.346E-1
1.000E0
 1 5
14 CID000039074 spirogermanium Stitch 1.094E-3 4.509E-2
3.346E-1
1.000E0
 1 5
15 CID000014819 lead sulfide Stitch 1.262E-3 4.509E-2
3.346E-1
1.000E0
 2 260
16 CID000025670 terbufos Stitch 1.750E-3 4.509E-2
3.346E-1
1.000E0
 1 8
17 CID009845545 Sch 44342 Stitch 1.969E-3 4.509E-2
3.346E-1
1.000E0
 1 9
18 CID000016180 amino-L Stitch 1.969E-3 4.509E-2
3.346E-1
1.000E0
 1 9
19 CID000095563 AC1L3ULO Stitch 2.406E-3 4.509E-2
3.346E-1
1.000E0
 1 11
20 CID000064145 Cereport Stitch 2.406E-3 4.509E-2
3.346E-1
1.000E0
 1 11
21 CID000137936 C-eq Stitch 2.406E-3 4.509E-2
3.346E-1
1.000E0
 1 11
22 CID006328143 polonium Stitch 2.843E-3 4.509E-2
3.346E-1
1.000E0
 1 13
23 CID000122092 M Hz Stitch 2.843E-3 4.509E-2
3.346E-1
1.000E0
 1 13
24 CID000516899 sodium perchlorate hydrate Stitch 3.061E-3 4.509E-2
3.346E-1
1.000E0
 1 14
25 CID005481766 Cd-U Stitch 3.716E-3 4.509E-2
3.346E-1
1.000E0
 1 17
26 CID005288616 I HE Stitch 3.716E-3 4.509E-2
3.346E-1
1.000E0
 1 17
27 ctd:D020123 Sirolimus CTD 3.854E-3 4.509E-2
3.346E-1
1.000E0
 2 458
28 CID000003835 AC1L1GTN Stitch 3.934E-3 4.509E-2
3.346E-1
1.000E0
 1 18
29 CID000036797 poly(lactic-co-glycolic acid Stitch 4.153E-3 4.509E-2
3.346E-1
1.000E0
 1 19
30 CID000449108 AC1L9MQJ Stitch 4.153E-3 4.509E-2
3.346E-1
1.000E0
 1 19
31 CID001122655 neurokinin-1 receptor antagonist Stitch 4.589E-3 4.509E-2
3.346E-1
1.000E0
 1 21
32 CID000151434 Db04047 Stitch 4.589E-3 4.509E-2
3.346E-1
1.000E0
 1 21
33 CID003806994 C35H51N9O8 Stitch 4.589E-3 4.509E-2
3.346E-1
1.000E0
 1 21
34 CID006438372 farnesylcysteine Stitch 4.589E-3 4.509E-2
3.346E-1
1.000E0
 1 21
35 CID000107700 1,1'-ethylidenebis(tryptophan Stitch 4.807E-3 4.509E-2
3.346E-1
1.000E0
 1 22
36 CID000446589 R-TB Stitch 4.807E-3 4.509E-2
3.346E-1
1.000E0
 1 22
37 CID000060418 NSC 615284 Stitch 5.025E-3 4.509E-2
3.346E-1
1.000E0
 1 23
38 CID000016637 poly(N-isopropylacrylamide Stitch 5.025E-3 4.509E-2
3.346E-1
1.000E0
 1 23
39 CID000024857 radon Stitch 5.025E-3 4.509E-2
3.346E-1
1.000E0
 1 23
40 CID000451928 PMEI Stitch 5.243E-3 4.509E-2
3.346E-1
1.000E0
 1 24
41 CID000452666 Ala-Val-Gly Stitch 5.243E-3 4.509E-2
3.346E-1
1.000E0
 1 24
42 CID000001154 AC1L1AUK Stitch 5.461E-3 4.509E-2
3.346E-1
1.000E0
 1 25
43 CID000216453 L-778,123 Stitch 5.461E-3 4.509E-2
3.346E-1
1.000E0
 1 25
44 CID004369498 A-A-X Stitch 5.679E-3 4.509E-2
3.346E-1
1.000E0
 1 26
45 CID000009923 pentafluorobenzyl alcohol Stitch 5.897E-3 4.509E-2
3.346E-1
1.000E0
 1 27
46 CID000010391 benzylamide Stitch 5.897E-3 4.509E-2
3.346E-1
1.000E0
 1 27
47 CID000446207 phenylalaninal Stitch 6.115E-3 4.509E-2
3.346E-1
1.000E0
 1 28
48 CID000008271 mephobarbital Stitch 6.115E-3 4.509E-2
3.346E-1
1.000E0
 1 28
49 CID000003628 NSC141633 Stitch 6.333E-3 4.509E-2
3.346E-1
1.000E0
 1 29
50 CID000123799 Mesotocin Stitch 6.333E-3 4.509E-2
3.346E-1
1.000E0
 1 29
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 62 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0015269 Exhibitionism DisGeNET BeFree 1.234E-3 3.819E-2
1.800E-1
7.649E-2
 1 4
2 C1858266 Bare Lymphocyte Syndrome, Type I DisGeNET Curated 2.466E-3 3.819E-2
1.800E-1
1.529E-1
 1 8
3 C0024793 Marek Disease DisGeNET BeFree 3.082E-3 3.819E-2
1.800E-1
1.911E-1
 1 10
4 20090604:Landers Amyotrophic lateral sclerosis GWAS 4.313E-3 3.819E-2
1.800E-1
2.674E-1
 1 14
5 C0035012 Reiter Syndrome DisGeNET BeFree 4.313E-3 3.819E-2
1.800E-1
2.674E-1
 1 14
6 C1449844 Pseudohypoaldosteronism, Type II DisGeNET BeFree 4.313E-3 3.819E-2
1.800E-1
2.674E-1
 1 14
7 C0010232 Cowpox DisGeNET BeFree 4.620E-3 3.819E-2
1.800E-1
2.865E-1
 1 15
8 C0339985 Idiopathic bronchiectasis DisGeNET Curated 4.928E-3 3.819E-2
1.800E-1
3.055E-1
 1 16
9 C0400936 Autoimmune liver disease DisGeNET BeFree 5.849E-3 4.030E-2
1.899E-1
3.627E-1
 1 19
10 C2931418 Bare lymphocyte syndrome 2 DisGeNET Curated 7.997E-3 4.545E-2
2.142E-1
4.958E-1
 1 26
11 C0014743 Erythema Nodosum DisGeNET Curated 8.304E-3 4.545E-2
2.142E-1
5.149E-1
 1 27
12 C1512433 High Grade Cervical Squamous Intraepithelial Neoplasia DisGeNET BeFree 9.530E-3 4.545E-2
2.142E-1
5.908E-1
 1 31
13 C1333762 Gastric Cardia Adenocarcinoma DisGeNET BeFree 9.530E-3 4.545E-2
2.142E-1
5.908E-1
 1 31
14 C0037284 Skin lesion DisGeNET BeFree 1.167E-2 4.925E-2
2.321E-1
7.236E-1
 1 38
15 C0426980 Motor symptoms DisGeNET BeFree 1.228E-2 4.925E-2
2.321E-1
7.615E-1
 1 40
16 C0340643 Dissection of aorta DisGeNET Curated 1.289E-2 4.925E-2
2.321E-1
7.994E-1
 1 42
17 C0034341 Pyruvate Carboxylase Deficiency Disease DisGeNET Curated 1.350E-2 4.925E-2
2.321E-1
8.373E-1
 1 44
Show 12 more annotations