Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc227_10, positive side

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1: GO: Molecular Function [Display Chart] 10 input genes in category / 32 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0004896 cytokine receptor activity 9.321E-21 2.983E-19 1.210E-18 2.983E-19 9 90
2 GO:0019838 growth factor binding 3.575E-11 5.721E-10 2.322E-9 1.144E-9 6 142
3 GO:0019955 cytokine binding 1.145E-9 1.221E-8 4.957E-8 3.664E-8 5 103
4 GO:0004911 interleukin-2 receptor activity 7.752E-7 4.961E-6 2.013E-5 2.481E-5 2 3
5 GO:0019976 interleukin-2 binding 7.752E-7 4.961E-6 2.013E-5 2.481E-5 2 3
6 GO:0019983 interleukin-9 binding 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
7 GO:0070119 ciliary neurotrophic factor binding 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
8 GO:0001532 interleukin-21 receptor activity 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
9 GO:0004919 interleukin-9 receptor activity 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
10 GO:0004900 erythropoietin receptor activity 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
11 GO:0019982 interleukin-7 binding 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
12 GO:0004903 growth hormone receptor activity 5.359E-4 1.429E-3 5.800E-3 1.715E-2 1 1
13 GO:0019981 interleukin-6 binding 1.071E-3 2.143E-3 8.697E-3 3.429E-2 1 2
14 GO:0004915 interleukin-6 receptor activity 1.071E-3 2.143E-3 8.697E-3 3.429E-2 1 2
15 GO:0004917 interleukin-7 receptor activity 1.071E-3 2.143E-3 8.697E-3 3.429E-2 1 2
16 GO:0004913 interleukin-4 receptor activity 1.071E-3 2.143E-3 8.697E-3 3.429E-2 1 2
17 GO:0004924 oncostatin-M receptor activity 1.607E-3 3.025E-3 1.228E-2
5.142E-2
 1 3
18 GO:0004897 ciliary neurotrophic factor receptor activity 2.142E-3 3.808E-3 1.545E-2
6.854E-2
 1 4
19 GO:0005138 interleukin-6 receptor binding 3.746E-3 6.309E-3 2.560E-2
1.199E-1
 1 7
20 GO:0005088 Ras guanyl-nucleotide exchange factor activity 6.485E-3 1.038E-2 4.211E-2
2.075E-1
 2 232
21 GO:0005126 cytokine receptor binding 9.908E-3 1.510E-2
6.128E-2
3.171E-1
 2 289
22 GO:0070064 proline-rich region binding 1.067E-2 1.538E-2
6.243E-2
3.414E-1
 1 20
23 GO:0005085 guanyl-nucleotide exchange factor activity 1.106E-2 1.538E-2
6.243E-2
3.538E-1
 2 306
24 GO:0042169 SH2 domain binding 1.808E-2 2.410E-2
9.781E-2
5.784E-1
 1 34
25 GO:0017046 peptide hormone binding 2.386E-2 3.054E-2
1.240E-1
7.635E-1
 1 45
Show 20 more annotations

2: GO: Biological Process [Display Chart] 10 input genes in category / 393 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0038110 interleukin-2-mediated signaling pathway 2.593E-6 5.476E-4 3.588E-3 1.019E-3 2 5
2 GO:0071352 cellular response to interleukin-2 3.888E-6 5.476E-4 3.588E-3 1.528E-3 2 6
3 GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 4.353E-6 5.476E-4 3.588E-3 1.711E-3 3 63
4 GO:0042509 regulation of tyrosine phosphorylation of STAT protein 7.987E-6 5.476E-4 3.588E-3 3.139E-3 3 77
5 GO:0007260 tyrosine phosphorylation of STAT protein 9.306E-6 5.476E-4 3.588E-3 3.657E-3 3 81
6 GO:0070669 response to interleukin-2 9.324E-6 5.476E-4 3.588E-3 3.664E-3 2 9
7 GO:0046427 positive regulation of JAK-STAT cascade 1.115E-5 5.476E-4 3.588E-3 4.380E-3 3 86
8 GO:1904894 positive regulation of STAT cascade 1.115E-5 5.476E-4 3.588E-3 4.380E-3 3 86
9 GO:0030101 natural killer cell activation 1.278E-5 5.581E-4 3.657E-3 5.023E-3 3 90
10 GO:0042976 activation of Janus kinase activity 3.102E-5 1.144E-3 7.494E-3 1.219E-2 2 16
11 GO:0018108 peptidyl-tyrosine phosphorylation 3.422E-5 1.144E-3 7.494E-3 1.345E-2 4 385
12 GO:0018212 peptidyl-tyrosine modification 3.492E-5 1.144E-3 7.494E-3 1.372E-2 4 387
13 GO:0046425 regulation of JAK-STAT cascade 7.145E-5 2.006E-3 1.314E-2 2.808E-2 3 160
14 GO:1904892 regulation of STAT cascade 7.145E-5 2.006E-3 1.314E-2 2.808E-2 3 160
15 GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 9.644E-5 2.527E-3 1.656E-2 3.790E-2 3 177
16 GO:0007259 JAK-STAT cascade 1.171E-4 2.708E-3 1.774E-2 4.604E-2 3 189
17 GO:0097696 STAT cascade 1.171E-4 2.708E-3 1.774E-2 4.604E-2 3 189
18 GO:0050730 regulation of peptidyl-tyrosine phosphorylation 2.372E-4 5.180E-3 3.394E-2
9.323E-2
 3 240
19 GO:1904098 regulation of protein O-linked glycosylation 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
20 GO:0098757 cellular response to interleukin-21 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
21 GO:0071355 cellular response to interleukin-9 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
22 GO:0033078 extrathymic T cell differentiation 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
23 GO:0045062 extrathymic T cell selection 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
24 GO:0038113 interleukin-9-mediated signaling pathway 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
25 GO:1904100 positive regulation of protein O-linked glycosylation 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
26 GO:0038114 interleukin-21-mediated signaling pathway 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
27 GO:0098756 response to interleukin-21 5.370E-4 7.816E-3
5.121E-2
2.110E-1
 1 1
28 GO:0032103 positive regulation of response to external stimulus 5.926E-4 8.318E-3
5.450E-2
2.329E-1
 3 328
29 GO:0098760 response to interleukin-7 1.074E-3 1.279E-2
8.378E-2
4.220E-1
 1 2
30 GO:0098761 cellular response to interleukin-7 1.074E-3 1.279E-2
8.378E-2
4.220E-1
 1 2
31 GO:0038162 erythropoietin-mediated signaling pathway 1.074E-3 1.279E-2
8.378E-2
4.220E-1
 1 2
32 GO:0038111 interleukin-7-mediated signaling pathway 1.074E-3 1.279E-2
8.378E-2
4.220E-1
 1 2
33 GO:0002384 hepatic immune response 1.074E-3 1.279E-2
8.378E-2
4.220E-1
 1 2
34 GO:0001819 positive regulation of cytokine production 1.198E-3 1.385E-2
9.073E-2
4.708E-1
 3 418
35 GO:0045621 positive regulation of lymphocyte differentiation 1.249E-3 1.402E-2
9.190E-2
4.909E-1
 2 100
36 GO:0071104 response to interleukin-9 1.610E-3 1.758E-2
1.152E-1
6.328E-1
 1 3
37 GO:0048660 regulation of smooth muscle cell proliferation 2.066E-3 1.989E-2
1.303E-1
8.119E-1
 2 129
38 GO:0038165 oncostatin-M-mediated signaling pathway 2.146E-3 1.989E-2
1.303E-1
8.435E-1
 1 4
39 GO:0006549 isoleucine metabolic process 2.146E-3 1.989E-2
1.303E-1
8.435E-1
 1 4
40 GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.146E-3 1.989E-2
1.303E-1
8.435E-1
 1 4
41 GO:0046449 creatinine metabolic process 2.146E-3 1.989E-2
1.303E-1
8.435E-1
 1 4
42 GO:0050729 positive regulation of inflammatory response 2.162E-3 1.989E-2
1.303E-1
8.496E-1
 2 132
43 GO:0048659 smooth muscle cell proliferation 2.194E-3 1.989E-2
1.303E-1
8.623E-1
 2 133
44 GO:0045580 regulation of T cell differentiation 2.227E-3 1.989E-2
1.303E-1
8.751E-1
 2 134
45 GO:0046631 alpha-beta T cell activation 2.293E-3 2.002E-2
1.312E-1
9.010E-1
 2 136
46 GO:0036017 response to erythropoietin 2.682E-3 2.027E-2
1.328E-1
1.000E0
 1 5
47 GO:0072338 cellular lactam metabolic process 2.682E-3 2.027E-2
1.328E-1
1.000E0
 1 5
48 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 2.682E-3 2.027E-2
1.328E-1
1.000E0
 1 5
49 GO:0000255 allantoin metabolic process 2.682E-3 2.027E-2
1.328E-1
1.000E0
 1 5
50 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway 2.682E-3 2.027E-2
1.328E-1
1.000E0
 1 5
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 10 input genes in category / 13 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0009897 external side of plasma membrane 2.597E-7 3.376E-6 1.074E-5 3.376E-6 5 310
2 GO:0070195 growth hormone receptor complex 5.246E-4 2.643E-3 8.404E-3 6.820E-3 1 1
3 GO:0043235 receptor complex 6.098E-4 2.643E-3 8.404E-3 7.928E-3 3 339
4 GO:0005900 oncostatin-M receptor complex 1.049E-3 3.408E-3 1.084E-2 1.364E-2 1 2
5 GO:0005896 interleukin-6 receptor complex 1.573E-3 3.408E-3 1.084E-2 2.045E-2 1 3
6 GO:0070110 ciliary neurotrophic factor receptor complex 1.573E-3 3.408E-3 1.084E-2 2.045E-2 1 3
7 GO:0098802 plasma membrane receptor complex 3.797E-3 7.051E-3 2.242E-2 4.936E-2 2 180
8 GO:0016324 apical plasma membrane 1.263E-2 1.965E-2
6.248E-2
1.641E-1
 2 335
9 GO:0032809 neuronal cell body membrane 1.511E-2 1.965E-2
6.248E-2
1.965E-1
 1 29
10 GO:0044298 cell body membrane 1.511E-2 1.965E-2
6.248E-2
1.965E-1
 1 29
11 GO:0045177 apical part of cell 2.009E-2 2.374E-2
7.551E-2
2.612E-1
 2 428
Show 6 more annotations

4: Human Phenotype [Display Chart] 6 input genes in category / 548 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 10 input genes in category / 799 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0008047 absent uterine NK cells 2.593E-9 2.072E-6 1.505E-5 2.072E-6 3 4
2 MP:0008046 absent NK cells 5.432E-8 2.170E-5 1.576E-4 4.340E-5 3 9
3 MP:0008876 decreased uterine NK cell number 2.348E-7 6.253E-5 4.541E-4 1.876E-4 3 14
4 MP:0001844 autoimmune response 7.748E-7 9.881E-5 7.175E-4 6.191E-4 6 419
5 MP:0005005 abnormal self tolerance 7.969E-7 9.881E-5 7.175E-4 6.367E-4 6 421
6 MP:0005000 abnormal immune tolerance 8.903E-7 9.881E-5 7.175E-4 7.114E-4 6 429
7 MP:0010776 abnormal placenta metrial gland morphology 9.893E-7 9.881E-5 7.175E-4 7.905E-4 3 22
8 MP:0008054 abnormal uterine NK cell morphology 9.893E-7 9.881E-5 7.175E-4 7.905E-4 3 22
9 MP:0010766 abnormal NK cell physiology 2.000E-6 1.776E-4 1.290E-3 1.598E-3 4 105
10 MP:0004256 abnormal maternal decidual layer morphology 4.177E-6 3.337E-4 2.423E-3 3.337E-3 3 35
11 MP:0002425 altered susceptibility to autoimmune disorder 7.584E-6 5.508E-4 4.000E-3 6.059E-3 5 335
12 MP:0001711 abnormal placenta morphology 1.107E-5 7.374E-4 5.354E-3 8.849E-3 5 362
13 MP:0002376 abnormal dendritic cell physiology 1.301E-5 7.996E-4 5.806E-3 1.040E-2 4 168
14 MP:0005070 impaired natural killer cell mediated cytotoxicity 1.946E-5 1.104E-3 8.014E-3 1.555E-2 3 58
15 MP:0005350 increased susceptibility to autoimmune disorder 2.072E-5 1.104E-3 8.014E-3 1.655E-2 4 189
16 MP:0011719 abnormal natural killer cell mediated cytotoxicity 2.381E-5 1.175E-3 8.533E-3 1.902E-2 3 62
17 MP:0002339 abnormal lymph node morphology 2.500E-5 1.175E-3 8.533E-3 1.998E-2 5 428
18 MP:0008096 abnormal plasma cell number 4.570E-5 2.028E-3 1.473E-2 3.651E-2 3 77
19 MP:0008568 abnormal interleukin secretion 5.048E-5 2.097E-3 1.523E-2 4.033E-2 5 495
20 MP:0001120 abnormal uterus morphology 5.383E-5 2.097E-3 1.523E-2 4.301E-2 4 241
21 MP:0009019 abnormal metestrus 5.512E-5 2.097E-3 1.523E-2 4.404E-2 2 12
22 MP:0008588 abnormal circulating interleukin level 6.408E-5 2.327E-3 1.690E-2
5.120E-2
 4 252
23 MP:0004974 decreased regulatory T cell number 6.817E-5 2.368E-3 1.720E-2
5.447E-2
 3 88
24 MP:0002439 abnormal plasma cell morphology 7.535E-5 2.509E-3 1.822E-2
6.021E-2
 3 91
25 MP:0008351 decreased gamma-delta intraepithelial T cell number 1.000E-4 3.073E-3 2.232E-2
7.991E-2
 2 16
26 MP:0010934 increased subcutaneous adipose tissue amount 1.000E-4 3.073E-3 2.232E-2
7.991E-2
 2 16
27 MP:0008751 abnormal interleukin level 1.199E-4 3.485E-3 2.530E-2
9.581E-2
 4 296
28 MP:0000726 absent lymphocyte 1.221E-4 3.485E-3 2.530E-2
9.757E-2
 3 107
29 MP:0000701 abnormal lymph node size 1.381E-4 3.790E-3 2.752E-2
1.104E-1
 4 307
30 MP:0008354 decreased mature gamma-delta T cell number 1.423E-4 3.790E-3 2.752E-2
1.137E-1
 2 19
31 MP:0008045 decreased NK cell number 1.474E-4 3.800E-3 2.759E-2
1.178E-1
 3 114
32 MP:0008801 abnormal erythroid progenitor cell morphology 1.716E-4 4.102E-3 2.979E-2
1.371E-1
 3 120
33 MP:0008895 abnormal intraepithelial T cell number 1.746E-4 4.102E-3 2.979E-2
1.395E-1
 2 21
34 MP:0008349 abnormal gamma-delta intraepithelial T cell morphology 1.746E-4 4.102E-3 2.979E-2
1.395E-1
 2 21
35 MP:0010210 abnormal circulating cytokine level 1.914E-4 4.369E-3 3.172E-2
1.529E-1
 4 334
36 MP:0001806 decreased IgM level 2.225E-4 4.893E-3 3.553E-2
1.778E-1
 3 131
37 MP:0009011 prolonged diestrus 2.291E-4 4.893E-3 3.553E-2
1.830E-1
 2 24
38 MP:0004794 increased anti-nuclear antigen antibody level 2.327E-4 4.893E-3 3.553E-2
1.859E-1
 3 133
39 MP:0002357 abnormal spleen white pulp morphology 2.421E-4 4.959E-3 3.601E-2
1.934E-1
 4 355
40 MP:0008698 abnormal interleukin-4 secretion 2.595E-4 5.086E-3 3.693E-2
2.074E-1
 3 138
41 MP:0013324 abnormal female reproductive gland morphology 2.610E-4 5.086E-3 3.693E-2
2.085E-1
 4 362
42 MP:0003850 abnormal thymocyte activation 2.695E-4 5.126E-3 3.722E-2
2.153E-1
 2 26
43 MP:0008894 abnormal intraepithelial T cell morphology 2.909E-4 5.405E-3 3.924E-2
2.324E-1
 2 27
44 MP:0001828 abnormal T cell activation 3.113E-4 5.652E-3 4.104E-2
2.487E-1
 4 379
45 MP:0010398 decreased liver glycogen level 3.361E-4 5.838E-3 4.239E-2
2.685E-1
 2 29
46 MP:0008344 abnormal mature gamma-delta T cell morphology 3.361E-4 5.838E-3 4.239E-2
2.685E-1
 2 29
47 MP:0004972 abnormal regulatory T cell number 3.450E-4 5.846E-3 4.245E-2
2.757E-1
 3 152
48 MP:0004941 abnormal regulatory T cell morphology 3.585E-4 5.846E-3 4.245E-2
2.865E-1
 3 154
49 MP:0020173 abnormal IgE level 3.585E-4 5.846E-3 4.245E-2
2.865E-1
 3 154
50 MP:0009010 abnormal diestrus 3.845E-4 6.050E-3 4.393E-2
3.073E-1
 2 31
Show 45 more annotations

6: Domain [Display Chart] 10 input genes in category / 34 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS50853 FN3 PROSITE 1.422E-17 3.790E-16 1.561E-15 4.835E-16 9 199
2 IPR003961 FN3 dom InterPro 2.230E-17 3.790E-16 1.561E-15 7.581E-16 9 209
3 SM00060 FN3 SMART 3.436E-15 3.894E-14 1.604E-13 1.168E-13 8 185
4 PS01355 HEMATOPO REC S F1 PROSITE 2.862E-12 2.432E-11 1.002E-10 9.729E-11 4 8
5 IPR003531 Hempt rcpt S F1 CS InterPro 5.150E-12 3.502E-11 1.442E-10 1.751E-10 4 9
6 PF00041 fn3 Pfam 7.773E-11 4.405E-10 1.814E-9 2.643E-9 6 162
7 IPR015321 TypeI recpt CBD InterPro 1.803E-8 7.662E-8 3.155E-7 6.130E-7 3 11
8 PF09240 IL6Ra-bind Pfam 1.803E-8 7.662E-8 3.155E-7 6.130E-7 3 11
9 IPR003528 Long hematopoietin rcpt CS InterPro 1.538E-6 5.228E-6 2.153E-5 5.228E-5 2 4
10 PS01352 HEMATOPO REC L F1 PROSITE 1.538E-6 5.228E-6 2.153E-5 5.228E-5 2 4
11 PF09067 EpoR lig-bind Pfam 2.562E-6 7.259E-6 2.989E-5 8.711E-5 2 5
12 IPR015152 Growth/epo recpt lig-bind InterPro 2.562E-6 7.259E-6 2.989E-5 8.711E-5 2 5
13 IPR003529 Hematopoietin rcpt Gp130 CS InterPro 5.377E-6 1.406E-5 5.792E-5 1.828E-4 2 7
14 PS01353 HEMATOPO REC L F2 PROSITE 7.168E-6 1.741E-5 7.169E-5 2.437E-4 2 8
15 IPR020466 IL-15 mml InterPro 5.338E-4 9.552E-4 3.934E-3 1.815E-2 1 1
16 PF12772 GHBP Pfam 5.338E-4 9.552E-4 3.934E-3 1.815E-2 1 1
17 IPR025871 GHBP InterPro 5.338E-4 9.552E-4 3.934E-3 1.815E-2 1 1
18 IPR009167 Erythropoietin rcpt InterPro 5.338E-4 9.552E-4 3.934E-3 1.815E-2 1 1
19 IPR020439 IL-15 InterPro 5.338E-4 9.552E-4 3.934E-3 1.815E-2 1 1
20 IPR003443 IL-15/IL-21 fam InterPro 1.067E-3 1.728E-3 7.116E-3 3.629E-2 1 2
21 PF02372 IL15 Pfam 1.067E-3 1.728E-3 7.116E-3 3.629E-2 1 2
22 IPR010457 IgC2-like lig-bd InterPro 2.134E-3 3.154E-3 1.299E-2
7.254E-2
 1 4
23 PF06328 Lep receptor Ig Pfam 2.134E-3 3.154E-3 1.299E-2
7.254E-2
 1 4
24 IPR003530 Hematopoietin rcpt L F3 CS InterPro 2.666E-3 3.626E-3 1.493E-2
9.065E-2
 1 5
25 PS01354 HEMATOPO REC L F3 PROSITE 2.666E-3 3.626E-3 1.493E-2
9.065E-2
 1 5
26 IPR001005 SANT/Myb InterPro 2.742E-2 3.585E-2
1.477E-1
9.322E-1
 1 52
27 IPR009079 4 helix cytokine-like core InterPro 3.881E-2 4.888E-2
2.013E-1
1.000E0
 1 74
Show 22 more annotations

7: Pathway [Display Chart] 10 input genes in category / 109 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 83077 Jak-STAT signaling pathway BioSystems: KEGG 7.132E-20 7.774E-18 4.099E-17 7.774E-18 10 156
2 83051 Cytokine-cytokine receptor interaction BioSystems: KEGG 1.951E-17 1.063E-15 5.607E-15 2.127E-15 10 270
3 692234 PI3K-Akt signaling pathway BioSystems: KEGG 7.872E-8 2.860E-6 1.508E-5 8.580E-6 6 342
4 P00036 Interleukin signaling pathway PantherDB 5.668E-7 1.545E-5 8.145E-5 6.178E-5 4 92
5 1469482 Th17 cell differentiation BioSystems: KEGG 1.041E-6 1.963E-5 1.035E-4 1.134E-4 4 107
6 1339142 Interleukin-6 family signaling BioSystems: REACTOME 1.081E-6 1.963E-5 1.035E-4 1.178E-4 3 27
7 137922 IL12-mediated signaling events BioSystems: Pathway Interaction Database 1.311E-5 2.041E-4 1.076E-3 1.429E-3 3 61
8 842771 Inflammatory bowel disease (IBD) BioSystems: KEGG 1.588E-5 2.164E-4 1.141E-3 1.731E-3 3 65
9 1458885 Th1 and Th2 cell differentiation BioSystems: KEGG 4.514E-5 5.466E-4 2.883E-3 4.920E-3 3 92
10 83078 Hematopoietic cell lineage BioSystems: KEGG 5.288E-5 5.764E-4 3.039E-3 5.764E-3 3 97
11 1339143 IL-6-type cytokine receptor ligand interactions BioSystems: REACTOME 1.095E-4 1.085E-3 5.721E-3 1.193E-2 2 20
12 M7747 IL 2 signaling pathway MSigDB C2 BIOCARTA (v6.0) 1.330E-4 1.208E-3 6.370E-3 1.450E-2 2 22
13 137988 IL2 signaling events mediated by STAT5 BioSystems: Pathway Interaction Database 2.496E-4 2.093E-3 1.103E-2 2.720E-2 2 30
14 137938 IL2 signaling events mediated by PI3K BioSystems: Pathway Interaction Database 3.810E-4 2.921E-3 1.540E-2 4.153E-2 2 37
15 M8615 IL-2 Receptor Beta Chain in T cell Activation MSigDB C2 BIOCARTA (v6.0) 4.020E-4 2.921E-3 1.540E-2 4.381E-2 2 38
16 1269581 G beta:gamma signalling through PI3Kgamma BioSystems: REACTOME 6.422E-4 4.324E-3 2.280E-2
7.000E-2
 2 48
17 138018 Downstream signaling in naive CD8+ T cells BioSystems: Pathway Interaction Database 6.969E-4 4.324E-3 2.280E-2
7.596E-2
 2 50
18 1269580 G-protein beta:gamma signalling BioSystems: REACTOME 7.250E-4 4.324E-3 2.280E-2
7.902E-2
 2 51
19 137976 IL2-mediated signaling events BioSystems: Pathway Interaction Database 7.537E-4 4.324E-3 2.280E-2
8.215E-2
 2 52
20 1269357 GPVI-mediated activation cascade BioSystems: REACTOME 8.126E-4 4.429E-3 2.335E-2
8.858E-2
 2 54
21 1269502 MAPK1/MAPK3 signaling BioSystems: REACTOME 9.056E-4 4.590E-3 2.420E-2
9.871E-2
 3 254
22 373901 HTLV-I infection BioSystems: KEGG 9.265E-4 4.590E-3 2.420E-2
1.010E-1
 3 256
23 1269501 MAPK family signaling cascades BioSystems: REACTOME 1.369E-3 6.490E-3 3.422E-2
1.493E-1
 3 293
24 1383035 Interleukin-12 signaling BioSystems: REACTOME 3.209E-3 1.458E-2
7.686E-2
3.498E-1
 1 4
25 1470923 Interleukin-4 and 13 signaling BioSystems: REACTOME 3.565E-3 1.554E-2
8.196E-2
3.886E-1
 2 114
26 213306 Measles BioSystems: KEGG 4.890E-3 2.050E-2
1.081E-1
5.330E-1
 2 134
27 1269505 MAPK1 (ERK2) activation BioSystems: REACTOME 7.208E-3 2.910E-2
1.534E-1
7.857E-1
 1 9
28 1269504 MAPK3 (ERK1) activation BioSystems: REACTOME 8.006E-3 2.999E-2
1.581E-1
8.727E-1
 1 10
29 M6917 Erythropoietin mediated neuroprotection through NF-kB MSigDB C2 BIOCARTA (v6.0) 8.803E-3 2.999E-2
1.581E-1
9.596E-1
 1 11
30 1269325 Interleukin-6 signaling BioSystems: REACTOME 8.803E-3 2.999E-2
1.581E-1
9.596E-1
 1 11
31 M9174 STAT3 Pathway MSigDB C2 BIOCARTA (v6.0) 8.803E-3 2.999E-2
1.581E-1
9.596E-1
 1 11
32 M5415 IL 4 signaling pathway MSigDB C2 BIOCARTA (v6.0) 8.803E-3 2.999E-2
1.581E-1
9.596E-1
 1 11
33 M13158 The IGF-1 Receptor and Longevity MSigDB C2 BIOCARTA (v6.0) 1.199E-2 3.177E-2
1.675E-1
1.000E0
 1 15
34 M11736 Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. MSigDB C2 BIOCARTA (v6.0) 1.199E-2 3.177E-2
1.675E-1
1.000E0
 1 15
35 1269328 Prolactin receptor signaling BioSystems: REACTOME 1.278E-2 3.177E-2
1.675E-1
1.000E0
 1 16
36 M1296 IL-7 Signal Transduction MSigDB C2 BIOCARTA (v6.0) 1.358E-2 3.177E-2
1.675E-1
1.000E0
 1 17
37 M6231 NO2-dependent IL 12 Pathway in NK cells MSigDB C2 BIOCARTA (v6.0) 1.358E-2 3.177E-2
1.675E-1
1.000E0
 1 17
38 M6705 Th1/Th2 Differentiation MSigDB C2 BIOCARTA (v6.0) 1.516E-2 3.177E-2
1.675E-1
1.000E0
 1 19
39 M12836 EPO Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 1.516E-2 3.177E-2
1.675E-1
1.000E0
 1 19
40 1269440 SOS-mediated signalling BioSystems: REACTOME 1.600E-2 3.177E-2
1.675E-1
1.000E0
 2 248
41 1269383 SHC1 events in EGFR signaling BioSystems: REACTOME 1.600E-2 3.177E-2
1.675E-1
1.000E0
 2 248
42 1269382 GRB2 events in EGFR signaling BioSystems: REACTOME 1.600E-2 3.177E-2
1.675E-1
1.000E0
 2 248
43 1269285 RAF/MAP kinase cascade BioSystems: REACTOME 1.600E-2 3.177E-2
1.675E-1
1.000E0
 2 248
44 1269471 ARMS-mediated activation BioSystems: REACTOME 1.650E-2 3.177E-2
1.675E-1
1.000E0
 2 252
45 1269468 Signalling to p38 via RIT and RIN BioSystems: REACTOME 1.650E-2 3.177E-2
1.675E-1
1.000E0
 2 252
46 1269470 Frs2-mediated activation BioSystems: REACTOME 1.662E-2 3.177E-2
1.675E-1
1.000E0
 2 253
47 M15926 Trefoil Factors Initiate Mucosal Healing MSigDB C2 BIOCARTA (v6.0) 1.675E-2 3.177E-2
1.675E-1
1.000E0
 1 21
48 M17406 Cytokine Network MSigDB C2 BIOCARTA (v6.0) 1.675E-2 3.177E-2
1.675E-1
1.000E0
 1 21
49 1269469 Prolonged ERK activation events BioSystems: REACTOME 1.687E-2 3.177E-2
1.675E-1
1.000E0
 2 255
50 1269632 Signaling by Leptin BioSystems: REACTOME 1.700E-2 3.177E-2
1.675E-1
1.000E0
 2 256
Show 45 more annotations

8: Pubmed [Display Chart] 10 input genes in category / 3512 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20503287 Interleukin-9 polymorphism in infants with respiratory syncytial virus infection: an opposite effect in boys and girls. Pubmed 4.449E-12 5.690E-9 4.974E-8 1.563E-8 6 204
2 19258923 Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Pubmed 4.583E-12 5.690E-9 4.974E-8 1.610E-8 6 205
3 17703412 Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. Pubmed 4.861E-12 5.690E-9 4.974E-8 1.707E-8 6 207
4 18829468 Ligand-independent homomeric and heteromeric complexes between interleukin-2 or -9 receptor subunits and the gamma chain. Pubmed 1.292E-11 1.135E-8 9.919E-8 4.539E-8 3 3
5 11702064 Critical role of IL-15-IL-15R for antigen-presenting cell functions in the innate immune response. Pubmed 5.169E-11 3.631E-8 3.174E-7 1.815E-7 3 4
6 15123770 Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain. Pubmed 1.292E-10 6.483E-8 5.667E-7 4.538E-7 3 5
7 7641685 Identification and cloning of a novel IL-15 binding protein that is structurally related to the alpha chain of the IL-2 receptor. Pubmed 1.292E-10 6.483E-8 5.667E-7 4.538E-7 3 5
8 18390713 The lymphopenic environment of CD132 (common gamma-chain)-deficient hosts elicits rapid homeostatic proliferation of naive T cells via IL-15. Pubmed 2.584E-10 1.008E-7 8.814E-7 9.074E-7 3 6
9 17855567 Gamma c cytokines condition the progressive differentiation of CD4+ T cells. Pubmed 2.584E-10 1.008E-7 8.814E-7 9.074E-7 3 6
10 17923507 CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells. Pubmed 4.521E-10 1.443E-7 1.262E-6 1.588E-6 3 7
11 7621883 Analysis of interleukin receptor gene expression in mouse fetal liver by quantitative polymerase chain reaction. Pubmed 4.521E-10 1.443E-7 1.262E-6 1.588E-6 3 7
12 18566388 A function for IL-7R for CD4+CD25+Foxp3+ T regulatory cells. Pubmed 7.233E-10 2.117E-7 1.850E-6 2.540E-6 3 8
13 11418623 Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex. Pubmed 1.085E-9 2.931E-7 2.562E-6 3.810E-6 3 9
14 20023630 Innate production of T(H)2 cytokines by adipose tissue-associated c-Kit(+)Sca-1(+) lymphoid cells. Pubmed 2.130E-9 4.988E-7 4.360E-6 7.481E-6 3 11
15 19084435 Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense. Pubmed 2.130E-9 4.988E-7 4.360E-6 7.481E-6 3 11
16 8499630 Hematopoietic growth factor receptor genes as markers of lineage commitment during in vitro development of hematopoietic cells. Pubmed 1.470E-8 3.227E-6 2.820E-5 5.162E-5 3 20
17 9324354 Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Pubmed 1.715E-8 3.542E-6 3.097E-5 6.022E-5 3 21
18 20424473 L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms. Pubmed 3.999E-8 6.373E-6 5.571E-5 1.404E-4 4 144
19 9176231 Interleukin-15 signals T84 colonic epithelial cells in the absence of the interleukin-2 receptor beta-chain. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
20 8797792 Towards prediction of cognate complexes between the WW domain and proline-rich ligands. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
21 19648279 Cutting edge: IL-15-independent NK cell response to mouse cytomegalovirus infection. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
22 23926072 Construction of unnatural heterodimeric receptors based on IL-2 and IL-6 receptor subunits. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
23 8026467 Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
24 27463037 Characterization of Receptor-Associated Protein Complex Assembly in Interleukin (IL)-2- and IL-15-Activated T-Cell Lines. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
25 8514792 Characterization of the human interleukin-2 receptor gamma chain gene. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
26 8648694 The human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surface. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
27 11750878 Alternate signalling pathways from the interleukin-2 receptor. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
28 15630141 Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
29 28111009 Glomerular common gamma chain confers B- and T-cell-independent protection against glomerulonephritis. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
30 11017787 A protective role of interleukin-15 in a mouse model for systemic infection with herpes simplex virus. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
31 8568232 Interaction of IL-15 with the shared IL-2 receptor beta and gamma c subunits. The IL-15/beta/gamma c receptor-ligand complex is less stable than the IL-2/beta/gamma c receptor-ligand complex. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
32 17082603 Functional interaction of common gamma-chain and growth hormone receptor signaling apparatus. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
33 18589435 Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
34 22363690 Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway. Pubmed 6.170E-8 6.373E-6 5.571E-5 2.167E-4 2 2
35 26744522 Improved Treatment of Breast Cancer with Anti-HER2 Therapy Requires Interleukin-21 Signaling in CD8+ T Cells. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
36 27573835 IL2Rβ-dependent signals drive terminal exhaustion and suppress memory development during chronic viral infection. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
37 22890824 Interleukin-15 plays an essential role in the pathogenesis of autoimmune diabetes in the NOD mouse. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
38 16116438 Model for growth hormone receptor activation based on subunit rotation within a receptor dimer. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
39 8049354 Soluble IL-2 receptor beta and gamma subunits: ligand binding and cooperativity. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
40 17056533 Combined IL-15/IL-15Ralpha immunotherapy maximizes IL-15 activity in vivo. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
41 16284400 Soluble interleukin-15 receptor alpha (IL-15R alpha)-sushi as a selective and potent agonist of IL-15 action through IL-15R beta/gamma. Hyperagonist IL-15 x IL-15R alpha fusion proteins. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
42 21984699 The basis of distinctive IL-2- and IL-15-dependent signaling: weak CD122-dependent signaling favors CD8+ T central-memory cell survival but not T effector-memory cell development. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
43 20538758 IL-15 has innate anti-tumor activity independent of NK and CD8 T cells. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
44 11886175 Oligomerization of IL-2Ralpha. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
45 11856346 GPI-microdomains (membrane rafts) and signaling of the multi-chain interleukin-2 receptor in human lymphoma/leukemia T cell lines. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
46 15767447 NK and NKT cell-independent contribution of interleukin-15 to innate protection against mucosal viral infection. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
47 28678791 Modeling the receptor pharmacology, pharmacokinetics, and pharmacodynamics of NKTR-214, a kinetically-controlled interleukin-2 (IL2) receptor agonist for cancer immunotherapy. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
48 28497365 Clinical utility of soluble interleukin-2 receptor in hemophagocytic syndromes: a systematic scoping review. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
49 19050240 Inhibition of tumor growth by NK1.1+ cells and CD8+ T cells activated by IL-15 through receptor beta/common gamma signaling in trans. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
50 23018461 Transient enhanced IL-2R signaling early during priming rapidly amplifies development of functional CD8+ T effector-memory cells. Pubmed 1.851E-7 1.250E-5 1.093E-4 6.500E-4 2 3
Show 45 more annotations

9: Interaction [Display Chart] 10 input genes in category / 166 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:JAK1 JAK1 interactions 1.943E-11 2.266E-9 1.290E-8 3.225E-9 6 122
2 int:JAK2 JAK2 interactions 2.730E-11 2.266E-9 1.290E-8 4.533E-9 6 129
3 int:IL2RG IL2RG interactions 2.998E-9 1.659E-7 9.441E-7 4.976E-7 4 36
4 int:IL15 IL15 interactions 7.258E-9 3.012E-7 1.715E-6 1.205E-6 3 8
5 int:IL15RA IL15RA interactions 2.848E-8 9.455E-7 5.382E-6 4.728E-6 3 12
6 int:SOCS3 SOCS3 interactions 8.364E-8 2.298E-6 1.308E-5 1.388E-5 4 81
7 int:STAT5B STAT5B interactions 9.692E-8 2.298E-6 1.308E-5 1.609E-5 4 84
8 int:STAT5A STAT5A interactions 3.096E-7 6.424E-6 3.657E-5 5.139E-5 4 112
9 int:IL2RB IL2RB interactions 6.383E-7 1.177E-5 6.701E-5 1.060E-4 3 32
10 int:CISH CISH interactions 9.177E-7 1.523E-5 8.672E-5 1.523E-4 3 36
11 int:IL21 IL21 interactions 4.303E-6 6.493E-5 3.696E-4 7.142E-4 2 6
12 int:SHC1 SHC1 interactions 1.160E-5 1.605E-4 9.135E-4 1.926E-3 4 278
13 int:IL2 IL2 interactions 1.890E-5 2.413E-4 1.374E-3 3.137E-3 2 12
14 int:IL9R IL9R interactions 8.556E-5 1.015E-3 5.775E-3 1.420E-2 2 25
15 int:PTPN6 PTPN6 interactions 1.101E-4 1.200E-3 6.830E-3 1.828E-2 3 176
16 int:SHB SHB interactions 1.157E-4 1.200E-3 6.830E-3 1.920E-2 2 29
17 int:IL6ST IL6ST interactions 2.327E-4 2.273E-3 1.294E-2 3.864E-2 2 41
18 int:PIK3R1 PIK3R1 interactions 3.140E-4 2.895E-3 1.648E-2
5.212E-2
 3 251
19 int:GRB10 GRB10 interactions 3.330E-4 2.909E-3 1.656E-2
5.528E-2
 2 49
20 int:STAT3 STAT3 interactions 5.397E-4 4.479E-3 2.550E-2
8.959E-2
 3 302
21 int:SOCS2 SOCS2 interactions 8.215E-4 6.494E-3 3.697E-2
1.364E-1
 2 77
22 int:SOCS1 SOCS1 interactions 9.310E-4 7.025E-3 3.999E-2
1.546E-1
 2 82
23 int:JAK3 JAK3 interactions 1.096E-3 7.907E-3 4.501E-2
1.819E-1
 2 89
24 int:WWP1 WWP1 interactions 1.195E-3 8.268E-3 4.706E-2
1.984E-1
 2 93
25 int:ELOB ELOB interactions 2.111E-3 1.292E-2
7.357E-2
3.504E-1
 2 124
26 int:IL21R IL21R interactions 2.258E-3 1.292E-2
7.357E-2
3.748E-1
 1 4
27 int:C12orf4 C12orf4 interactions 2.258E-3 1.292E-2
7.357E-2
3.748E-1
 1 4
28 int:IL9 IL9 interactions 2.258E-3 1.292E-2
7.357E-2
3.748E-1
 1 4
29 int:GH2 GH2 interactions 2.258E-3 1.292E-2
7.357E-2
3.748E-1
 1 4
30 int:SYK SYK interactions 2.606E-3 1.442E-2
8.207E-2
4.326E-1
 2 138
31 int:ELOC ELOC interactions 3.191E-3 1.703E-2
9.692E-2
5.297E-1
 2 153
32 int:IL7 IL7 interactions 3.385E-3 1.703E-2
9.692E-2
5.619E-1
 1 6
33 int:IL12RB2 IL12RB2 interactions 3.385E-3 1.703E-2
9.692E-2
5.619E-1
 1 6
34 int:PTPN1 PTPN1 interactions 3.656E-3 1.785E-2
1.016E-1
6.068E-1
 2 164
35 int:PLCG1 PLCG1 interactions 3.832E-3 1.818E-2
1.035E-1
6.361E-1
 2 168
36 int:TBCK TBCK interactions 4.511E-3 2.080E-2
1.184E-1
7.488E-1
 1 8
37 int:EPO EPO interactions 5.074E-3 2.160E-2
1.229E-1
8.422E-1
 1 9
38 int:IL12B IL12B interactions 5.074E-3 2.160E-2
1.229E-1
8.422E-1
 1 9
39 int:GH1 GH1 interactions 5.074E-3 2.160E-2
1.229E-1
8.422E-1
 1 9
40 int:WWP2 WWP2 interactions 5.436E-3 2.256E-2
1.284E-1
9.024E-1
 2 201
41 int:DGCR2 DGCR2 interactions 5.636E-3 2.282E-2
1.299E-1
9.356E-1
 1 10
42 int:STAT1 STAT1 interactions 5.810E-3 2.296E-2
1.307E-1
9.645E-1
 2 208
43 int:IL2RA IL2RA interactions 6.198E-3 2.393E-2
1.362E-1
1.000E0
 1 11
44 int:IL13RA1 IL13RA1 interactions 6.760E-3 2.431E-2
1.384E-1
1.000E0
 1 12
45 int:OSMR OSMR interactions 6.760E-3 2.431E-2
1.384E-1
1.000E0
 1 12
46 int:CRYZL1 CRYZL1 interactions 6.760E-3 2.431E-2
1.384E-1
1.000E0
 1 12
47 int:PTPN11 PTPN11 interactions 7.002E-3 2.431E-2
1.384E-1
1.000E0
 2 229
48 int:LYN LYN interactions 7.180E-3 2.431E-2
1.384E-1
1.000E0
 2 232
49 int:KITLG KITLG interactions 7.321E-3 2.431E-2
1.384E-1
1.000E0
 1 13
50 int:IL4 IL4 interactions 7.321E-3 2.431E-2
1.384E-1
1.000E0
 1 13
Show 45 more annotations

10: Cytoband [Display Chart] 10 input genes in category / 11 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 5p13-p12 5p13-p12 8.653E-4 4.759E-3 1.437E-2 9.518E-3 1 3
2 1p31.3-p31.2 1p31.3-p31.2 8.653E-4 4.759E-3 1.437E-2 9.518E-3 1 3
3 16p11 16p11 2.018E-3 7.399E-3 2.234E-2 2.220E-2 1 7
4 4q31 4q31 3.169E-3 8.716E-3 2.632E-2 3.486E-2 1 11
5 19p13.3-p13.2 19p13.3-p13.2 4.032E-3 8.871E-3 2.679E-2 4.436E-2 1 14
6 5p13.1 5p13.1 5.756E-3 1.055E-2 3.187E-2
6.332E-2
 1 20
7 Yq12 Yq12 1.063E-2 1.670E-2
5.042E-2
1.169E-1
 1 37
8 Xq13.1 Xq13.1 1.433E-2 1.971E-2
5.952E-2
1.577E-1
 1 50
9 22q13.1 22q13.1 2.539E-2 2.916E-2
8.807E-2
2.792E-1
 1 89
10 1q21 1q21 2.651E-2 2.916E-2
8.807E-2
2.916E-1
 1 93
Show 5 more annotations

11: Transcription Factor Binding Site [Display Chart] 7 input genes in category / 30 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 10 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 602 Fibronectin type III domain containing|Interleukin receptors genenames.org 2.174E-14 1.304E-13 3.195E-13 1.304E-13 6 42
2 555 Receptor Tyrosine Kinases|Fibronectin type III domain containing|V-set domain containing|Immunoglobulin like domain containing genenames.org 1.202E-8 3.605E-8 8.831E-8 7.209E-8 5 160
3 471 CD molecules|Tumor necrosis factor superfamily genenames.org 1.070E-6 2.140E-6 5.243E-6 6.420E-6 5 394
4 716 CD molecules|Interleukin receptors|Pseudoautosomal region 2 genenames.org 5.484E-3 8.226E-3 2.015E-2 3.290E-2 1 10
5 601 Interleukins|PDZ domain containing genenames.org 2.339E-2 2.807E-2
6.877E-2
1.403E-1
 1 43

13: Coexpression [Display Chart] 10 input genes in category / 1482 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20460173-ImmPortCytokineReceptors Human Immune Kong10 308genes ImmPort CytokineReceptors GeneSigDB 9.950E-17 1.475E-13 1.162E-12 1.475E-13 9 303
2 20460173-ImmPortInterleukinReceptors Human Immune Kong10 43genes ImmPort InterleukinReceptors GeneSigDB 3.767E-15 2.791E-12 2.199E-11 5.582E-12 6 40
3 M1985 Inflammatory cytokines and their receptors modulated in brain tumors after treatment with an oncocytic virus, a potential anticancer therapy. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.368E-9 1.170E-6 9.218E-6 3.510E-6 4 44
4 12946996-Table3 Human Lymphoma Kaminski03 33genes GeneSigDB 8.915E-8 3.303E-5 2.602E-4 1.321E-4 3 22
5 17823238-TableS5 Human EmbryonicStemCell Soh07 469genes GeneSigDB 7.208E-7 2.136E-4 1.683E-3 1.068E-3 5 462
6 17638852-Table2 Human Lymphoma Shin07 62genes GeneSigDB 1.425E-6 3.521E-4 2.774E-3 2.113E-3 3 54
7 19802007-SuppTable1 Human StemCell Novakova10 89genes Interferons/Receptors GeneSigDB 1.964E-6 4.158E-4 3.276E-3 2.911E-3 3 60
8 M1851 Up-regulated genes that best disciminate plasmablastic plasmacytoma from plasmacytic plasmacytoma tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.056E-6 5.661E-4 4.460E-3 4.529E-3 4 259
9 M5897 Genes up-regulated by IL6 [GeneID=3569] via STAT3 [GeneID=6774], e.g., during acute phase response. MSigDB H: Hallmark Gene Sets (v6.0) 6.046E-6 9.956E-4 7.844E-3 8.960E-3 3 87
10 17174972-TableS1 Human Zola07 426genes CellDifferentiationMarkers GeneSigDB 9.504E-6 1.409E-3 1.110E-2 1.409E-2 4 345
11 16270046-SuppTable1 Human Lymphoma Martinez-Delgado05 135genes GeneSigDB 1.065E-5 1.435E-3 1.130E-2 1.578E-2 3 105
12 18435859-ShorterGeneList Mouse Breast Piechocki08 558genes GeneSigDB 1.334E-5 1.648E-3 1.298E-2 1.977E-2 4 376
13 19014521-TableS6b Human Breast Reyal08 159genes GeneSigDB 3.353E-5 3.823E-3 3.012E-2 4.970E-2 3 154
14 12163391-Table2 Human Brain Watson02 24genes GeneSigDB 4.617E-5 4.795E-3 3.778E-2
6.842E-2
 2 24
15 M4222 Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 12 h versus the untreated cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 7.087E-5 4.795E-3 3.778E-2
1.050E-1
 3 198
16 M3819 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 16 h versus DC cells stimulated with poly(I:C) (TLR3 agonist) at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
17 M6008 Genes down-regulated in dendritic cells: wildtype versus CIITA [GeneID=4261] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
18 M8690 Genes up-regulated in monocytes (6h): muramyl dipeptide [PubChem=11620162] versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
19 M5030 Genes down-regulated in comparison of SP1 thymocytes versus SP4 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
20 M5950 Genes up-regulated during transplant rejection. MSigDB H: Hallmark Gene Sets (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
21 M3631 Genes down-regulated in comparison of unstimulated CD8 T cells at 48 h versus CD8 T cells at 48 h after stimulation with IL12. MSigDB C7: Immunologic Signatures (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
22 M5932 Genes defining inflammatory response. MSigDB H: Hallmark Gene Sets (v6.0) 7.301E-5 4.795E-3 3.778E-2
1.082E-1
 3 200
23 18483624-Table1 Human Stomach Marcos08 45genes GeneSigDB 7.766E-5 4.795E-3 3.778E-2
1.151E-1
 2 31
24 20458058-TableS3c Human HeadandNeck Thurlow10 34genes GeneSigDB 7.766E-5 4.795E-3 3.778E-2
1.151E-1
 2 31
25 20103679-ST3-C Human Breast Wood10 302genes GeneSigDB 9.557E-5 5.666E-3 4.464E-2
1.416E-1
 3 219
26 M1392 Cluster 8 of genes distinguishing among different B lymphocyte neoplasms. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.051E-4 5.990E-3 4.720E-2
1.558E-1
 2 36
27 M8537 Genes down-regulated in lymph nodes from patients with mantle cell lymphoma (MCL) compared to the non-malignant hyperplastic lymph nodes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.235E-4 6.780E-3
5.342E-2
1.831E-1
 2 39
28 M5916 Genes encoding proteins over-represented on the apical surface of epithelial cells, e.g., important for cell polarity (apical area). MSigDB H: Hallmark Gene Sets (v6.0) 1.575E-4 8.337E-3
6.569E-2
2.334E-1
 2 44
29 M950 Genes up-regulated in A549 cells (lung carcinoma) upon infection with RSV (respiratory syncytial virus) and down-regulated by further treatment with ribavirin [PubChem=5064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.120E-4 1.083E-2
8.534E-2
3.141E-1
 2 51
30 M6890 Genes down-regulated in at least one of three multiple myeloma (MM) cell lines by TSA [PubChem=5562]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.213E-4 1.093E-2
8.614E-2
3.280E-1
 3 291
31 19286929-SuppTable2l Mouse Lung Rangasamy09 75genes GeneSigDB 2.377E-4 1.136E-2
8.954E-2
3.523E-1
 2 54
32 11982591-Table1 Human Immune Frenkel 73genes GeneSigDB 3.554E-4 1.646E-2
1.297E-1
5.266E-1
 2 66
33 M17123 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing 11q23 rearrangements. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.838E-4 1.693E-2
1.334E-1
5.688E-1
 3 351
34 17638852-Table6 Human Lymphoma Shin07 76genes GeneSigDB 3.884E-4 1.693E-2
1.334E-1
5.756E-1
 2 69
35 18172295-SuppTable4 Human Bone Heller08 693genes GeneSigDB 4.133E-4 1.741E-2
1.372E-1
6.125E-1
 3 360
36 M11428 Inflammatory cytokines, chemokines and their cognate receptors up-regulated in THP-1 cells (monocyte) after treatment with PSMD4 [GeneID=5710]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.347E-4 1.741E-2
1.372E-1
6.442E-1
 2 73
37 20166207-Table6 Human Leukemia Rigolin10 82genes GeneSigDB 4.347E-4 1.741E-2
1.372E-1
6.442E-1
 2 73
38 20460173-ImmPortCentrocytevsNaive Human Immune Kong10 109genes ImmPort CentrocytevsNaive GeneSigDB 5.349E-4 2.083E-2
1.641E-1
7.927E-1
 2 81
39 M3737 Genes up-regulated in OV-90 cells (ovarian cancer) exposed to ascites which inhibited invasion. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.482E-4 2.083E-2
1.641E-1
8.124E-1
 2 82
40 20460173-ImmPortCentroblastvsNaive Human Immune Kong10 112genes ImmPort CentroblastvsNaive GeneSigDB 6.168E-4 2.281E-2
1.797E-1
9.141E-1
 2 87
41 16509772-TableS1 Human StemCell Coller06 136genes GeneSigDB 6.310E-4 2.281E-2
1.797E-1
9.351E-1
 2 88
42 18922855-Table1 Human StemCell Kuttruff08 108genes GeneSigDB 7.976E-4 2.814E-2
2.217E-1
1.000E0
 2 99
43 M8513 Genes up-regulated in the normal-like subtype of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.323E-4 3.213E-2
2.532E-1
1.000E0
 3 476
44 17638894-Table1 Mouse Breast Piechocki07 120genes Gefitinib GeneSigDB 9.655E-4 3.252E-2
2.562E-1
1.000E0
 2 109
45 M2527 Genes representing Th1 / cytotoxic module in sputum during asthma exacerbations. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.055E-3 3.360E-2
2.647E-1
1.000E0
 2 114
46 15947096-TableS2 Mouse BoneMarrow Jacquelin05 153genes GeneSigDB 1.055E-3 3.360E-2
2.647E-1
1.000E0
 2 114
47 16014681-table2 Human StemCell Bohgaki05 118genes GeneSigDB 1.092E-3 3.360E-2
2.647E-1
1.000E0
 2 116
48 M6297 Genes down-regulated in macrophages stimulated by IFNG [GeneID=3458] for 3h: control versus primed by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.227E-3 3.360E-2
2.647E-1
1.000E0
 2 123
49 17192395-TableS1 Human StemCell Macaulay07 150genes GeneSigDB 1.247E-3 3.360E-2
2.647E-1
1.000E0
 2 124
50 M3069 Genes down-regulated during in vitro maturation of CD14+ [GeneID=929] monocytes (day 0) into immature (day 7) and mature dendritic cells (day 14). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.327E-3 3.360E-2
2.647E-1
1.000E0
 2 128
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 10 input genes in category / 1168 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Limb Muscle/T cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Limb Muscle/T cell Tabula Muris Consortium 4.061E-6 4.079E-3 3.117E-2 4.743E-3 3 72
2 GSM538365 500 alpha beta T cells, T.4Mem.Sp, 4+ 8- 25- 44hi 122lo, Spleen, avg-3 Immgen.org, GSE15907 1.167E-5 4.079E-3 3.117E-2 1.364E-2 4 343
3 GSM538362 500 alpha beta T cells, T.4Mem.LN, TCRb CD44high CD122lo CD4, Lymph Node, avg-3 Immgen.org, GSE15907 1.236E-5 4.079E-3 3.117E-2 1.444E-2 4 348
4 GSM538371 500 alpha beta T cells, T.4Mem44h62l.Sp, CD4 TCRb CD44hi CD62Llo, Spleen, avg-3 Immgen.org, GSE15907 1.397E-5 4.079E-3 3.117E-2 1.632E-2 4 359
5 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Fat/natural killer cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Fat/natural killer cell Tabula Muris Consortium 3.128E-5 7.306E-3
5.583E-2
 3.653E-2 3 142
6 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Fat/T cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Fat/T cell Tabula Muris Consortium 6.553E-5 1.062E-2
8.117E-2
7.654E-2
 3 182
7 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Liver/natural killer cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Liver/natural killer cell Tabula Muris Consortium 6.769E-5 1.062E-2
8.117E-2
7.906E-2
 3 184
8 Immune cells (IMM)/Immune cells (IMM) d Immune cells (IMM)/Immune cells (IMM) d 7.801E-5 1.062E-2
8.117E-2
9.111E-2
 3 193
9 facebase RNAseq e14.5 palate poster proximal ERK2 WT 2500 K3 facebase RNAseq e14.5 palate poster proximal ERK2 WT 2500 K3 Gudmap RNAseq 1.488E-4 1.062E-2
8.117E-2
1.738E-1
 3 240
10 PP GMP 500 K3 PP GMP top-relative-expression-ranked 500 k-means-cluster#3 PCBC 1.678E-4 1.062E-2
8.117E-2
1.960E-1
 3 250
11 10X Human 8K PBMC CD4 T-cells (IL7R, CD3D, CD3E) Subtype CD4 T-cells (IL7R, CD3D, CD3E)-CD4 T-cells subclass-1 (ITGB1, ANXA1, KLRB1) Top 200 Genes 10X Human 8K PBMC CD4 T-cells (IL7R, CD3D, CD3E) Subtype CD4 T-cells (IL7R, CD3D, CD3E)-CD4 T-cells subclass-1 (ITGB1, ANXA1, KLRB1) Top 200 Genes 2.015E-4 1.062E-2
8.117E-2
2.354E-1
 3 266
12 GSM538414 500 alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1 Immgen.org, GSE15907 2.787E-4 1.062E-2
8.117E-2
3.256E-1
 3 297
13 GSM538398 500 alpha beta T cells, T.8Mem.Sp, 4- 8+ 25- 44hi 122hi, Spleen, avg-3 Immgen.org, GSE15907 2.956E-4 1.062E-2
8.117E-2
3.453E-1
 3 303
14 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Subtype Flt1.Mgp Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Stalk Subtype Flt1.Mgp Top 200 Genes 3.072E-4 1.062E-2
8.117E-2
3.588E-1
 3 307
15 BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1.Mgp Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Stalk. .Flt1 Endothelial Stalk. .Flt1 Subtype Endothelial Stalk. .Flt1.Mgp Top 200 Genes BrainMap 3.072E-4 1.062E-2
8.117E-2
3.588E-1
 3 307
16 GSM538412 500 alpha beta T cells, T.8Nve.PP, TCR+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1 Immgen.org, GSE15907 3.375E-4 1.062E-2
8.117E-2
3.942E-1
 3 317
17 GSM404000 100 CD positive, CD4 Test JS, 4+8-B220-, Spleen, avg-3 Immgen.org, GSE15907 3.407E-4 1.062E-2
8.117E-2
3.979E-1
 2 61
18 GSM605756 500 alpha beta T cells, T.4.Pa.BDC, 4+ 8- BDC+, Pancreas, avg-2 Immgen.org, GSE15907 3.730E-4 1.062E-2
8.117E-2
4.357E-1
 3 328
19 GSM538395 500 alpha beta T cells, T.8Mem.LN, CD8 TCRb CD44high CD122high, Lymph Node, avg-3 Immgen.org, GSE15907 3.763E-4 1.062E-2
8.117E-2
4.396E-1
 3 329
20 GSM538406 500 alpha beta T cells, T.8Nve.LN, 4- 8+ 25- 62Lhi 44lo, Lymph Node, avg-3 Immgen.org, GSE15907 3.933E-4 1.062E-2
8.117E-2
4.594E-1
 3 334
21 GSM605770 500 alpha beta T cells, T.8.Sp.B16, 4- 8+ TCR+ 45+, B16 Melanoma Spleen, avg-3 Immgen.org, GSE15907 3.968E-4 1.062E-2
8.117E-2
4.635E-1
 3 335
22 GSM605758 500 alpha beta T cells, T.4.PLN.BDC, 4+ 8- BDC+, Lymph Node, avg-3 Immgen.org, GSE15907 4.003E-4 1.062E-2
8.117E-2
4.675E-1
 3 336
23 GSM538413 500 alpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1 Immgen.org, GSE15907 4.003E-4 1.062E-2
8.117E-2
4.675E-1
 3 336
24 GSM403987 500 CD positive, CD4 Test DB, 4+8-B220-, Spleen, avg-1 Immgen.org, GSE15907 4.073E-4 1.062E-2
8.117E-2
4.757E-1
 3 338
25 GSM605763 500 alpha beta T cells, T.4.TI.B16, 4+ 8- TCR+ 45+, B16 Melanoma Tumor, avg-3 Immgen.org, GSE15907 4.073E-4 1.062E-2
8.117E-2
4.757E-1
 3 338
26 GSM538382 500 alpha beta T cells, T.4Nve.Sp, 4+ 8- 25- 62Lhi 44lo, Spleen, avg-4 Immgen.org, GSE15907 4.108E-4 1.062E-2
8.117E-2
4.798E-1
 3 339
27 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/immature natural killer cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/immature natural killer cell Tabula Muris Consortium 4.234E-4 1.062E-2
8.117E-2
4.945E-1
 2 68
28 GSM399365 500 alpha beta T cells, T.4FP3+25+.Sp, 4+ 8- GFP+ 25+, Spleen, avg-3 Immgen.org, GSE15907 4.288E-4 1.062E-2
8.117E-2
5.009E-1
 3 344
29 GSM538412 100 alpha beta T cells, T.8Nve.PP, TCR+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1 Immgen.org, GSE15907 4.359E-4 1.062E-2
8.117E-2
5.092E-1
 2 69
30 GSM538368 500 alpha beta T cells, T.4Mem44h62l.LN, CD4 TCRb CD44hi CD62Llo, Lymph Node, avg-3 Immgen.org, GSE15907 4.361E-4 1.062E-2
8.117E-2
5.094E-1
 3 346
31 Mouse Lung Development Lungmap Mouse Fluidigm Fibroblast Subtype MatrixFB-A E18.5 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Fibroblast Subtype MatrixFB-A E18.5 Top 200 Genes 4.586E-4 1.062E-2
8.117E-2
5.357E-1
 3 352
32 GSM538288 100 NK cells, NK.49CI-.Sp, NK1.1+ CD3- Ly49C/I-, Spleen, avg-3 Immgen.org, GSE15907 4.615E-4 1.062E-2
8.117E-2
5.391E-1
 2 71
33 Sample Type by Project: Shred 1/TCGA-Esophagus/Esophageal Carcinoma/Adenocarcinoma/2/2 Sample Type by Project: Shred 1/TCGA-Esophagus/Esophageal Carcinoma/Adenocarcinoma/2/2 TCGA-Esophagus 4.615E-4 1.062E-2
8.117E-2
5.391E-1
 2 71
34 GSM538294 100 NK cells, NK.DAP10-.Sp, NK1.1+ TCRb-, Spleen, avg-3 Immgen.org, GSE15907 4.615E-4 1.062E-2
8.117E-2
5.391E-1
 2 71
35 GSM538285 100 NK cells, NK.49CI+.Sp, NK1.1+ CD3- Ly49C/I+, Spleen, avg-3 Immgen.org, GSE15907 4.615E-4 1.062E-2
8.117E-2
5.391E-1
 2 71
36 GSM538415 500 alpha beta T cells, T.8Nve.Sp, 4- 8+ 25- 62Lhi 44lo, Spleen, avg-3 Immgen.org, GSE15907 4.663E-4 1.062E-2
8.117E-2
5.446E-1
 3 354
37 GSM538409 500 alpha beta T cells, T.8Nve.MLN, 4- 8+ 25- 62Lhi 44lo, Lymph Node, avg-3 Immgen.org, GSE15907 4.740E-4 1.062E-2
8.117E-2
5.537E-1
 3 356
38 GSM538312 100 NK cells, NK.MCMV7.Sp, CD3-,NK1.1+, Spleen, avg-3 Immgen.org, GSE15907 4.746E-4 1.062E-2
8.117E-2
5.543E-1
 2 72
39 GSM605814 100 NK cells, NK.49H+.Sp, NK1.1+ Ly49H+, Spleen, avg-3 Immgen.org, GSE15907 4.746E-4 1.062E-2
8.117E-2
5.543E-1
 2 72
40 GSM403986 500 CD positive, CD4 Test NA, 4+8-B220-, Spleen, avg-1 Immgen.org, GSE15907 4.779E-4 1.062E-2
8.117E-2
5.582E-1
 3 357
41 GSM605909 500 CD positive, T.8Nve.Sp.OT1, CD8+ CD45.1+, Spleen, avg-3 Immgen.org, GSE15907 4.819E-4 1.062E-2
8.117E-2
5.628E-1
 3 358
42 GSM404000 500 CD positive, CD4 Test JS, 4+8-B220-, Spleen, avg-3 Immgen.org, GSE15907 4.858E-4 1.062E-2
8.117E-2
5.674E-1
 3 359
43 GSM538291 100 NK cells, NK.b2m-.Sp, NK1.1+ TCRb-, Spleen, avg-3 Immgen.org, GSE15907 4.878E-4 1.062E-2
8.117E-2
5.698E-1
 2 73
44 GSM538309 100 NK cells, NK.MCMV1.Sp, CD3-,NK1.1+, Spleen, avg-3 Immgen.org, GSE15907 4.878E-4 1.062E-2
8.117E-2
5.698E-1
 2 73
45 GSM538315 100 NK cells, NK.Sp, NK1.1+, Spleen, avg-3 Immgen.org, GSE15907 4.878E-4 1.062E-2
8.117E-2
5.698E-1
 2 73
46 GSM538297 100 NK cells, NK.DAP12-.Sp, NK1.1+ CD3-, Spleen, avg-3 Immgen.org, GSE15907 5.013E-4 1.062E-2
8.117E-2
5.855E-1
 2 74
47 GSM605817 100 NK cells, NK.49H-.Sp, NK1.1+, Spleen, avg-3 Immgen.org, GSE15907 5.013E-4 1.062E-2
8.117E-2
5.855E-1
 2 74
48 Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 1 Lungmap Mouse Lung E16.5 Matrix fibroblast Subtype Mature fibroblast 1 Lungmap CCHMC 5.058E-4 1.062E-2
8.117E-2
5.908E-1
 3 364
49 GSM399370 500 alpha beta T cells, T.4SP24-.Th, 4+ 8- TCRhi 24-/lo, Thymus, avg-3 Immgen.org, GSE15907 5.099E-4 1.062E-2
8.117E-2
5.956E-1
 3 365
50 GSM605904 500 alpha beta T cells, T.8Mem.Sp.OT1.d100.LisOva, CD8+ CD45.1+, Spleen, avg-3 Immgen.org, GSE15907 5.099E-4 1.062E-2
8.117E-2
5.956E-1
 3 365
Show 45 more annotations

15: Computational [Display Chart] 9 input genes in category / 57 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M6286 MODULE 265 Caner module 265: IL receptors. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.011E-9 3.996E-7 1.850E-6 3.996E-7 4 29
2 M5770 MODULE 63 Porins / transporters. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.608E-7 1.313E-5 6.079E-5 2.626E-5 5 211
3 M18643 MODULE 73 Genes in the cancer module 73. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.751E-7 1.540E-5 7.127E-5 4.988E-5 3 23
4 M18183 MODULE 121 Genes in the cancer module 121. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.080E-6 1.540E-5 7.127E-5 6.159E-5 4 99
5 M1653 MODULE 223 Immune (defense) response. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.580E-6 5.221E-5 2.417E-4 2.611E-4 4 142
6 M688 MODULE 27 Genes in the cancer module 27. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.032E-6 5.730E-5 2.653E-4 3.438E-4 5 355
7 M15983 MODULE 46 Genes in the cancer module 46. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.005E-5 6.688E-5 3.096E-4 5.729E-4 5 394
8 M19421 MODULE 85 Genes in the cancer module 85. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.016E-5 6.688E-5 3.096E-4 5.792E-4 3 51
9 M12401 MODULE 75 Immune response. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.056E-5 6.688E-5 3.096E-4 6.019E-4 5 398
10 M13974 MODULE 259 RTK signaling. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.248E-4 4.131E-3 1.912E-2 4.131E-2 2 46
11 M15076 MODULE 175 Genes in the cancer module 175. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.984E-4 4.742E-3 2.195E-2
5.691E-2
 2 54
12 M4082 MODULE 234 Bone remodeling. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.984E-4 4.742E-3 2.195E-2
5.691E-2
 2 54
13 M17161 MODULE 199 Genes in the cancer module 199. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.112E-3 4.875E-3 2.257E-2
6.338E-2
 2 57
14 M12285 MODULE 120 Genes in the cancer module 120. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.768E-3 7.200E-3 3.333E-2
1.008E-1
 2 72
15 M8807 MODULE 208 Genes in the cancer module 208. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.231E-3 1.988E-2
9.202E-2
2.982E-1
 2 125
16 M13121 MODULE 171 Genes in the cancer module 171. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.432E-3 2.291E-2
1.061E-1
3.666E-1
 2 139
Show 11 more annotations

16: MicroRNA [Display Chart] 10 input genes in category / 323 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-143-3p:TargetScan hsa-miR-143-3p TargetScan 1.264E-5 4.082E-3 2.595E-2 4.082E-3 3 345
2 hsa-miR-450a-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.475E-5 7.690E-3 4.888E-2 2.737E-2 2 100
3 hsa-miR-6857-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.818E-5 7.690E-3 4.888E-2 2.848E-2 2 102
4 hsa-miR-6810-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.524E-5 7.690E-3 4.888E-2 3.076E-2 2 106
5 hsa-miR-2110:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.545E-4 9.978E-3
6.343E-2
 4.989E-2 2 135
6 hsa-miR-5688:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.447E-4 1.028E-2
6.535E-2
7.903E-2
 2 170
7 hsa-miR-3150a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.592E-4 1.028E-2
6.535E-2
8.373E-2
 2 175
8 hsa-miR-6763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.592E-4 1.028E-2
6.535E-2
8.373E-2
 2 175
9 hsa-miR-495-3p:Functional MTI Functional MTI miRTarbase 2.865E-4 1.028E-2
6.535E-2
9.253E-2
 2 184
10 hsa-miR-5580-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.727E-4 1.126E-2
7.155E-2
1.204E-1
 2 210
11 hsa-miR-503-5p:TargetScan hsa-miR-503-5p TargetScan 3.834E-4 1.126E-2
7.155E-2
1.238E-1
 2 213
12 hsa-miR-517c:mirSVR highEffct hsa-miR-517c:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.654E-4 1.522E-2
9.673E-2
1.826E-1
 2 259
13 hsa-miR-421:TargetScan hsa-miR-421 TargetScan 9.248E-4 2.248E-2
1.429E-1
2.987E-1
 2 332
14 hsa-miR-342-5p:mirSVR highEffct hsa-miR-342-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.009E-3 2.248E-2
1.429E-1
3.260E-1
 2 347
15 hsa-miR-140-3p.2:TargetScan hsa-miR-140-3p.2 TargetScan 1.044E-3 2.248E-2
1.429E-1
3.372E-1
 2 353
16 hsa-miR-4292:mirSVR highEffct hsa-miR-4292:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.330E-3 2.684E-2
1.706E-1
4.295E-1
 2 399
17 hsa-miR-125b-5p:Functional MTI Functional MTI miRTarbase 1.548E-3 2.942E-2
1.870E-1
5.001E-1
 2 431
18 hsa-miR-1305:PITA hsa-miR-1305:PITA TOP PITA 1.708E-3 3.064E-2
1.948E-1
5.516E-1
 2 453
19 hsa-miR-1537-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.351E-3 3.997E-2
2.540E-1
7.593E-1
 1 17
20 hsa-miR-1277-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.489E-3 4.020E-2
2.555E-1
8.040E-1
 1 18
Show 15 more annotations

17: Drug [Display Chart] 10 input genes in category / 3887 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ctd:D009173 Mycophenolic Acid CTD 7.988E-10 3.105E-6 2.746E-5 3.105E-6 5 117
2 CID000428410 NSC237521 Stitch 1.557E-8 2.155E-5 1.906E-4 6.052E-5 5 211
3 CID000114777 theaflavin Stitch 2.100E-8 2.155E-5 1.906E-4 8.165E-5 5 224
4 ctd:C402696 TMC 120A CTD 2.218E-8 2.155E-5 1.906E-4 8.621E-5 4 75
5 CID000019920 LS109 Stitch 1.634E-7 1.270E-4 1.123E-3 6.350E-4 5 338
6 DB00004 Denileukin diftitox Drug Bank 5.174E-7 2.661E-4 2.353E-3 2.011E-3 2 3
7 DB00041 Aldesleukin Drug Bank 5.174E-7 2.661E-4 2.353E-3 2.011E-3 2 3
8 CID000484125 K-S-L Stitch 5.477E-7 2.661E-4 2.353E-3 2.129E-3 3 39
9 ctd:C006794 brevianamide A CTD 1.034E-6 4.184E-4 3.700E-3 4.021E-3 3 48
10 CID000451379 Ossirene Stitch 1.172E-6 4.184E-4 3.700E-3 4.554E-3 3 50
11 CID000073050 HT-2 toxin Stitch 1.245E-6 4.184E-4 3.700E-3 4.838E-3 3 51
12 ctd:D005620 Freund's Adjuvant CTD 1.344E-6 4.184E-4 3.700E-3 5.225E-3 4 208
13 ctd:C000488 cladosporin CTD 1.399E-6 4.184E-4 3.700E-3 5.440E-3 3 53
14 CID006419747 Syk inhibitor Stitch 1.939E-6 4.958E-4 4.384E-3 7.538E-3 3 59
15 ctd:C490266 neoechinulin A CTD 1.939E-6 4.958E-4 4.384E-3 7.538E-3 3 59
16 CID000097711 g130 Stitch 2.041E-6 4.958E-4 4.384E-3 7.933E-3 3 60
17 CID000007909 MIBK Stitch 3.257E-6 7.448E-4 6.586E-3 1.266E-2 3 70
18 ctd:D013241 Sterigmatocystin CTD 3.698E-6 7.986E-4 7.062E-3 1.438E-2 3 73
19 CID005489469 AC1NUR9D Stitch 4.824E-6 9.868E-4 8.726E-3 1.875E-2 2 8
20 CID000004271 H944 Stitch 7.435E-6 1.434E-3 1.268E-2 2.890E-2 3 92
21 CID003035979 Denny-Jaffe reagent Stitch 7.749E-6 1.434E-3 1.268E-2 3.012E-2 2 10
22 ctd:D063086 Organothiophosphates CTD 9.468E-6 1.664E-3 1.471E-2 3.680E-2 2 11
23 CID000008007 butylamino Stitch 9.846E-6 1.664E-3 1.471E-2 3.827E-2 3 101
24 CID000006451 bromcresol green Stitch 1.272E-5 2.061E-3 1.822E-2 4.946E-2 3 110
25 CID000002909 cyclophorine Stitch 2.313E-5 3.597E-3 3.180E-2
8.992E-2
 4 427
26 CID004369451 T1 d Stitch 3.905E-5 5.837E-3
5.162E-2
1.518E-1
 3 160
27 CID000521017 HPCs Stitch 4.203E-5 6.050E-3
5.350E-2
1.634E-1
 3 164
28 CID000454923 XK234 Stitch 4.436E-5 6.158E-3
5.446E-2
1.724E-1
 3 167
29 CID000187741 AC1L4LFZ Stitch 4.737E-5 6.349E-3
5.615E-2
1.841E-1
 2 24
30 4153 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP Up 5.099E-5 6.607E-3
5.843E-2
1.982E-1
 3 175
31 4776 UP Norcyclobenzaprine [303-50-4]; Up 200; 15.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 5.545E-5 6.856E-3
6.063E-2
2.156E-1
 3 180
32 5613 DN Phenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 5.825E-5 6.856E-3
6.063E-2
2.264E-1
 3 183
33 5935 UP trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.016E-5 6.856E-3
6.063E-2
2.339E-1
 3 185
34 5854 UP Levonordefrin [829-74-3]; Up 200; 21.8uM; PC3; HT HG-U133A Broad Institute CMAP Up 6.212E-5 6.856E-3
6.063E-2
2.415E-1
 3 187
35 1370 DN Atropine-N-oxide hydrochloride [4574-60-1]; Down 200; 11.8uM; HL60; HG-U133A Broad Institute CMAP Down 7.143E-5 6.856E-3
6.063E-2
2.776E-1
 3 196
36 2354 DN Ketoprofen [22071-15-4]; Down 200; 15.8uM; HL60; HT HG-U133A Broad Institute CMAP Down 7.252E-5 6.856E-3
6.063E-2
2.819E-1
 3 197
37 6402 DN 3-nitropropionic acid; Down 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP Down 7.252E-5 6.856E-3
6.063E-2
2.819E-1
 3 197
38 3187 UP Clofilium tosylate [92953-10-1]; Up 200; 7.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.252E-5 6.856E-3
6.063E-2
2.819E-1
 3 197
39 2264 UP Tranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.362E-5 6.856E-3
6.063E-2
2.861E-1
 3 198
40 3609 DN Sulfamethoxypyridazine [80-35-3]; Down 200; 14.2uM; MCF7; HT HG-U133A Broad Institute CMAP Down 7.362E-5 6.856E-3
6.063E-2
2.861E-1
 3 198
41 6446 UP Butylparaben [94-26-8]; Up 200; 20.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.362E-5 6.856E-3
6.063E-2
2.861E-1
 3 198
42 3576 UP Thiethylperazine malate [52239-63-1]; Up 200; 6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.473E-5 6.856E-3
6.063E-2
2.905E-1
 3 199
43 6687 UP Nafronyl oxalate [3200-06-4]; Up 200; 8.4uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.585E-5 6.856E-3
6.063E-2
2.948E-1
 3 200
44 ctd:D015232 Dinoprostone CTD 1.076E-4 9.314E-3
8.236E-2
4.181E-1
 3 225
45 CID000072231 Apomab Stitch 1.078E-4 9.314E-3
8.236E-2
4.191E-1
 2 36
46 CID000003794 WHI-P131 Stitch 1.203E-4 1.016E-2
8.986E-2
4.675E-1
 2 38
47 CID000146070 Il 10 Stitch 1.334E-4 1.103E-2
9.754E-2
5.184E-1
 2 40
48 CID000050587 thymopentin Stitch 1.402E-4 1.135E-2
1.004E-1
5.449E-1
 2 41
49 CID005462311 boron Stitch 1.594E-4 1.256E-2
1.111E-1
6.194E-1
 3 257
50 CID003003000 Gp55 Stitch 1.616E-4 1.256E-2
1.111E-1
6.282E-1
 2 44
Show 45 more annotations

18: Disease [Display Chart] 10 input genes in category / 487 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0011615 Dermatitis, Atopic DisGeNET Curated 4.946E-8 1.521E-5 1.029E-4 2.409E-5 6 411
2 C0013595 Eczema DisGeNET Curated 7.219E-8 1.521E-5 1.029E-4 3.516E-5 6 438
3 C0085110 Severe Combined Immunodeficiency DisGeNET Curated 9.369E-8 1.521E-5 1.029E-4 4.563E-5 5 215
4 C0023493 Adult T-Cell Lymphoma/Leukemia DisGeNET Curated 1.528E-7 1.860E-5 1.258E-4 7.440E-5 6 497
5 C0030481 Tropical Spastic Paraparesis DisGeNET BeFree 9.144E-7 8.897E-5 6.020E-4 4.453E-4 3 33
6 C1279481 X-Linked Combined Immunodeficiency Diseases DisGeNET Curated 1.096E-6 8.897E-5 6.020E-4 5.338E-4 3 35
7 C0543687 Thymic alymphoplasia DisGeNET BeFree 3.424E-6 2.382E-4 1.612E-3 1.668E-3 2 5
8 C0032131 Plasmacytoma DisGeNET Curated 3.723E-5 2.266E-3 1.534E-2 1.813E-2 3 112
9 C0033774 Pruritus DisGeNET Curated 4.462E-5 2.415E-3 1.634E-2 2.173E-2 3 119
10 C0268398 Familial lichen amyloidosis DisGeNET Curated 8.376E-5 4.079E-3 2.760E-2 4.079E-2 3 147
11 C0037928 Spinal Cord Diseases DisGeNET Curated 1.193E-4 5.087E-3 3.442E-2
5.811E-2
 2 27
12 C0032285 Pneumonia DisGeNET Curated 1.341E-4 5.087E-3 3.442E-2
6.531E-2
 4 476
13 C0011603 Dermatitis DisGeNET Curated 1.358E-4 5.087E-3 3.442E-2
6.613E-2
 3 173
14 C0401151 Chronic diarrhea DisGeNET Curated 1.791E-4 6.231E-3 4.216E-2
8.724E-2
 2 33
15 C0005956 Bone Marrow Diseases DisGeNET Curated 2.017E-4 6.549E-3 4.432E-2
9.824E-2
 2 35
16 C0007570 Celiac Disease DisGeNET Curated 3.878E-4 8.122E-3
5.496E-2
1.889E-1
 3 247
17 C3899278 Early Rheumatoid Arthritis DisGeNET BeFree 4.644E-4 8.122E-3
5.496E-2
2.262E-1
 2 53
18 C0008677 Bronchitis, Chronic DisGeNET Curated 4.821E-4 8.122E-3
5.496E-2
2.348E-1
 2 54
19 C1522378 Leukemia, Large Granular Lymphocytic DisGeNET Curated 5.185E-4 8.122E-3
5.496E-2
2.525E-1
 2 56
20 C0152031 Joint swelling DisGeNET Curated 5.562E-4 8.122E-3
5.496E-2
2.709E-1
 2 58
21 C1865597 Hypoplastic nasal bridge DisGeNET Curated 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
22 cv:C0271568 Laron-type isolated somatotropin defect Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
23 C4280494 Hypotrophic bridge of nose DisGeNET Curated 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
24 C4024599 Chronic oral candidiasis DisGeNET Curated 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
25 OMIN:312863 COMBINED IMMUNODEFICIENCY, X-LINKED; CIDX OMIM 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
26 C1852429 Cataract, Variable Zonular Pulverulent DisGeNET BeFree 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
27 cv:C1279481 X-linked severe combined immunodeficiency Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
28 cv:C1706416 Combined immunodeficiency, X-linked Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
29 OMIN:262500 LARON SYNDROME OMIM 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
30 C1845604 Recurrent bacterial meningitis DisGeNET Curated 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
31 cv:CN169363 IL21R immunodeficiency Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
32 OMIN:105250 AMYLOIDOSIS, PRIMARY CUTANEOUS OMIM 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
33 cv:CN130638 Serum level of interleukin 6 Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
34 C3554687 IL21R IMMUNODEFICIENCY DisGeNET Curated 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
35 C3808820 Hepatitis, chronic, due to Cryptosporidium infection DisGeNET Curated 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
36 cv:CN070041 Serum level of interleukin-6 soluble receptor Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
37 cv:C0268397 Cutaneous amyloidosis Clinical Variations 6.171E-4 8.122E-3
5.496E-2
3.005E-1
 1 1
38 C0751967 Multiple Sclerosis, Relapsing-Remitting DisGeNET Curated 7.640E-4 9.791E-3
6.625E-2
3.721E-1
 2 68
39 C0015544 Failure to Thrive DisGeNET BeFree 7.865E-4 9.822E-3
6.646E-2
3.830E-1
 2 69
40 C0345967 Malignant mesothelioma DisGeNET Curated 9.109E-4 1.103E-2
7.463E-2
4.436E-1
 3 331
41 C0398686 Primary immune deficiency disorder DisGeNET BeFree 9.285E-4 1.103E-2
7.463E-2
4.522E-1
 2 75
42 C0023492 Leukemia, T-Cell DisGeNET Curated 1.116E-3 1.294E-2
8.754E-2
5.433E-1
 3 355
43 C0745411 irregular bleeding DisGeNET BeFree 1.234E-3 1.366E-2
9.241E-2
6.009E-1
 1 2
44 C1839305 Decreased number of CD8+ T cells DisGeNET Curated 1.234E-3 1.366E-2
9.241E-2
6.009E-1
 1 2
45 C0029456 Osteoporosis DisGeNET Curated 1.317E-3 1.425E-2
9.645E-2
6.415E-1
 3 376
46 C0879615 Stromal Neoplasm DisGeNET BeFree 1.363E-3 1.443E-2
9.764E-2
6.638E-1
 2 91
47 C0178468 Autoimmune thyroid disease DisGeNET BeFree 1.547E-3 1.581E-2
1.070E-1
7.532E-1
 2 97
48 C1704272 Benign Prostatic Hyperplasia DisGeNET BeFree 1.738E-3 1.581E-2
1.070E-1
8.463E-1
 3 414
49 C0003862 Arthralgia DisGeNET Curated 1.843E-3 1.581E-2
1.070E-1
8.976E-1
 2 106
50 cv:C1851490 Familial erythrocytosis, 1 Clinical Variations 1.850E-3 1.581E-2
1.070E-1
9.011E-1
 1 3
Show 45 more annotations