Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc228_7, positive side

Go To Start Page
Input Parameters [Show Detail]
Training Results [Expand All] [Download All] [Sparse Matrix]
Display pValues and Scores as Table row limit

1: GO: Molecular Function [Display Chart] 7 input genes in category / 28 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0004951 cholecystokinin receptor activity 1.206E-7 3.377E-6 1.326E-5 3.377E-6 2 2
2 GO:0005179 hormone activity 9.830E-6 8.881E-5 3.488E-4 2.752E-4 3 124
3 GO:0008528 G protein-coupled peptide receptor activity 1.186E-5 8.881E-5 3.488E-4 3.321E-4 3 132
4 GO:0001653 peptide receptor activity 1.269E-5 8.881E-5 3.488E-4 3.553E-4 3 135
5 GO:0005184 neuropeptide hormone activity 6.333E-5 3.547E-4 1.393E-3 1.773E-3 2 33
6 GO:0031739 cholecystokinin receptor binding 3.751E-4 1.313E-3 5.156E-3 1.050E-2 1 1
7 GO:0015054 gastrin receptor activity 3.751E-4 1.313E-3 5.156E-3 1.050E-2 1 1
8 GO:0031741 type B gastrin/cholecystokinin receptor binding 3.751E-4 1.313E-3 5.156E-3 1.050E-2 1 1
9 GO:0004946 bombesin receptor activity 1.125E-3 3.500E-3 1.374E-2 3.150E-2 1 3
10 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity 2.249E-3 6.297E-3 2.473E-2
6.297E-2
 1 6
11 GO:0035014 phosphatidylinositol 3-kinase regulator activity 3.372E-3 8.582E-3 3.370E-2
9.441E-2
 1 9
12 GO:0004435 phosphatidylinositol phospholipase C activity 1.046E-2 2.440E-2
9.583E-2
2.928E-1
 1 28
13 GO:0071855 neuropeptide receptor binding 1.157E-2 2.493E-2
9.789E-2
3.240E-1
 1 31
14 GO:0070888 E-box binding 1.306E-2 2.576E-2
1.012E-1
3.656E-1
 1 35
15 GO:0004629 phospholipase C activity 1.380E-2 2.576E-2
1.012E-1
3.864E-1
 1 37
16 GO:0008188 neuropeptide receptor activity 1.713E-2 2.998E-2
1.177E-1
4.797E-1
 1 46
17 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding 2.634E-2 4.338E-2
1.703E-1
7.374E-1
 1 71
Show 12 more annotations

2: GO: Biological Process [Display Chart] 7 input genes in category / 187 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0007631 feeding behavior 9.089E-8 1.132E-5 6.580E-5 1.700E-5 4 135
2 GO:0038188 cholecystokinin signaling pathway 1.211E-7 1.132E-5 6.580E-5 2.265E-5 2 2
3 GO:0090274 positive regulation of somatostatin secretion 7.264E-7 4.528E-5 2.631E-4 1.358E-4 2 4
4 GO:0090273 regulation of somatostatin secretion 1.815E-6 8.487E-5 4.932E-4 3.395E-4 2 6
5 GO:0070253 somatostatin secretion 3.387E-6 1.267E-4 7.362E-4 6.334E-4 2 8
6 GO:0046717 acid secretion 1.038E-5 3.234E-4 1.879E-3 1.940E-3 3 126
7 GO:0001696 gastric acid secretion 2.065E-5 5.516E-4 3.205E-3 3.861E-3 2 19
8 GO:0032094 response to food 9.862E-5 2.126E-3 1.236E-2 1.844E-2 2 41
9 GO:0042755 eating behavior 1.035E-4 2.126E-3 1.236E-2 1.936E-2 2 42
10 GO:0002209 behavioral defense response 1.137E-4 2.126E-3 1.236E-2 2.126E-2 2 44
11 GO:0051930 regulation of sensory perception of pain 1.412E-4 2.201E-3 1.279E-2 2.641E-2 2 49
12 GO:0051931 regulation of sensory perception 1.412E-4 2.201E-3 1.279E-2 2.641E-2 2 49
13 GO:1903532 positive regulation of secretion by cell 3.648E-4 5.248E-3 3.050E-2
6.823E-2
 3 417
14 GO:0031644 regulation of neurological system process 4.360E-4 5.688E-3 3.305E-2
8.154E-2
 2 86
15 GO:0051047 positive regulation of secretion 4.563E-4 5.688E-3 3.305E-2
8.532E-2
 3 450
16 GO:0031016 pancreas development 4.988E-4 5.728E-3 3.328E-2
9.328E-2
 2 92
17 GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway 5.207E-4 5.728E-3 3.328E-2
9.737E-2
 2 94
18 GO:0022600 digestive system process 6.248E-4 6.491E-3 3.772E-2
1.168E-1
 2 103
19 GO:0090277 positive regulation of peptide hormone secretion 7.381E-4 7.028E-3 4.084E-2
1.380E-1
 2 112
20 GO:0031989 bombesin receptor signaling pathway 7.516E-4 7.028E-3 4.084E-2
1.406E-1
 1 2
21 GO:0002793 positive regulation of peptide secretion 7.915E-4 7.048E-3 4.095E-2
1.480E-1
 2 116
22 GO:0019233 sensory perception of pain 1.070E-3 9.092E-3
5.283E-2
2.000E-1
 2 135
23 GO:0046887 positive regulation of hormone secretion 1.353E-3 1.081E-2
6.281E-2
2.530E-1
 2 152
24 GO:0001764 neuron migration 1.497E-3 1.081E-2
6.281E-2
2.800E-1
 2 160
25 GO:0002023 reduction of food intake in response to dietary excess 1.503E-3 1.081E-2
6.281E-2
2.810E-1
 1 4
26 GO:0061074 regulation of neural retina development 1.503E-3 1.081E-2
6.281E-2
2.810E-1
 1 4
27 GO:0055123 digestive system development 1.591E-3 1.102E-2
6.405E-2
2.976E-1
 2 165
28 GO:0007586 digestion 1.808E-3 1.207E-2
7.016E-2
3.381E-1
 2 176
29 GO:1902866 regulation of retina development in camera-type eye 1.878E-3 1.211E-2
7.038E-2
3.512E-1
 1 5
30 GO:0035881 amacrine cell differentiation 2.629E-3 1.639E-2
9.521E-2
4.916E-1
 1 7
31 GO:0090276 regulation of peptide hormone secretion 3.194E-3 1.926E-2
1.119E-1
5.972E-1
 2 235
32 GO:0002791 regulation of peptide secretion 3.328E-3 1.945E-2
1.130E-1
6.224E-1
 2 240
33 GO:0051901 positive regulation of mitochondrial depolarization 4.128E-3 2.144E-2
1.246E-1
7.719E-1
 1 11
34 GO:0008343 adult feeding behavior 4.128E-3 2.144E-2
1.246E-1
7.719E-1
 1 11
35 GO:0014049 positive regulation of glutamate secretion 4.128E-3 2.144E-2
1.246E-1
7.719E-1
 1 11
36 GO:0031017 exocrine pancreas development 4.128E-3 2.144E-2
1.246E-1
7.719E-1
 1 11
37 GO:0007204 positive regulation of cytosolic calcium ion concentration 4.500E-3 2.171E-2
1.262E-1
8.415E-1
 2 280
38 GO:0030072 peptide hormone secretion 4.563E-3 2.171E-2
1.262E-1
8.533E-1
 2 282
39 GO:0090087 regulation of peptide transport 4.787E-3 2.171E-2
1.262E-1
8.952E-1
 2 289
40 GO:0002790 peptide secretion 4.819E-3 2.171E-2
1.262E-1
9.012E-1
 2 290
41 GO:1904181 positive regulation of membrane depolarization 4.877E-3 2.171E-2
1.262E-1
9.120E-1
 1 13
42 GO:0032099 negative regulation of appetite 4.877E-3 2.171E-2
1.262E-1
9.120E-1
 1 13
43 GO:0046883 regulation of hormone secretion 5.216E-3 2.224E-2
1.292E-1
9.754E-1
 2 302
44 GO:0032096 negative regulation of response to food 5.251E-3 2.224E-2
1.292E-1
9.820E-1
 1 14
45 GO:0051480 regulation of cytosolic calcium ion concentration 5.351E-3 2.224E-2
1.292E-1
1.000E0
 2 306
46 GO:0032230 positive regulation of synaptic transmission, GABAergic 6.000E-3 2.439E-2
1.417E-1
1.000E0
 1 16
47 GO:0030157 pancreatic juice secretion 6.373E-3 2.483E-2
1.443E-1
1.000E0
 1 17
48 GO:0001821 histamine secretion 6.373E-3 2.483E-2
1.443E-1
1.000E0
 1 17
49 GO:0051608 histamine transport 7.121E-3 2.635E-2
1.531E-1
1.000E0
 1 19
50 GO:0015833 peptide transport 7.221E-3 2.635E-2
1.531E-1
1.000E0
 2 357
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 7 input genes in category / 10 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043195 terminal bouton 7.049E-4 7.049E-3 2.065E-2 7.049E-3 2 112
2 GO:0043679 axon terminus 1.926E-3 7.334E-3 2.148E-2 1.926E-2 2 186
3 GO:0044306 neuron projection terminus 2.200E-3 7.334E-3 2.148E-2 2.200E-2 2 199
4 GO:0043203 axon hillock 2.935E-3 7.337E-3 2.149E-2 2.935E-2 1 8
5 GO:0043194 axon initial segment 4.765E-3 8.688E-3 2.545E-2 4.765E-2 1 13
6 GO:0033267 axon part 5.213E-3 8.688E-3 2.545E-2
5.213E-2
 2 309
7 GO:0098793 presynapse 6.315E-3 9.021E-3 2.642E-2
6.315E-2
 2 341
8 GO:0044304 main axon 2.687E-2 3.358E-2
9.836E-2
2.687E-1
 1 74
Show 3 more annotations

4: Human Phenotype [Display Chart] 1 input genes in category / 55 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0012642 Cerebellar agenesis 2.124E-4 1.168E-2
5.368E-2
 1.168E-2 1 1
2 HP:0001684 Secundum atrial septal defect 2.762E-3 3.944E-2
1.812E-1
1.519E-1
 1 13
3 HP:0002594 Pancreatic hypoplasia 3.399E-3 3.944E-2
1.812E-1
1.870E-1
 1 16
4 HP:0010557 Overlapping fingers 3.824E-3 3.944E-2
1.812E-1
2.103E-1
 1 18
5 HP:0100800 Aplasia/Hypoplasia of the pancreas 4.037E-3 3.944E-2
1.812E-1
2.220E-1
 1 19
6 HP:0000857 Neonatal insulin-dependent diabetes mellitus 4.461E-3 3.944E-2
1.812E-1
2.454E-1
 1 21
7 HP:0012094 Abnormal pancreas size 5.311E-3 3.944E-2
1.812E-1
2.921E-1
 1 25
8 HP:0000331 Short chin 5.736E-3 3.944E-2
1.812E-1
3.155E-1
 1 27
9 HP:0040063 Decreased adipose tissue 7.861E-3 4.124E-2
1.894E-1
4.323E-1
 1 37
10 HP:0003758 Reduced subcutaneous adipose tissue 7.861E-3 4.124E-2
1.894E-1
4.323E-1
 1 37
11 HP:0001738 Exocrine pancreatic insufficiency 8.923E-3 4.124E-2
1.894E-1
4.908E-1
 1 42
12 HP:0012092 Abnormality of exocrine pancreas physiology 9.135E-3 4.124E-2
1.894E-1
5.024E-1
 1 43
13 HP:0002581 Pancreatic insufficiency 1.062E-2 4.124E-2
1.894E-1
5.842E-1
 1 50
14 HP:0002570 Steatorrhea 1.147E-2 4.124E-2
1.894E-1
6.310E-1
 1 54
15 HP:0000444 Convex nasal ridge 1.190E-2 4.124E-2
1.894E-1
6.543E-1
 1 56
16 HP:0001001 Abnormality of subcutaneous fat tissue 1.232E-2 4.124E-2
1.894E-1
6.777E-1
 1 58
17 HP:0002630 Fat malabsorption 1.275E-2 4.124E-2
1.894E-1
7.011E-1
 1 60
18 HP:0000609 Optic nerve hypoplasia 1.593E-2 4.869E-2
2.236E-1
8.764E-1
 1 75
19 HP:0000831 Insulin-resistant diabetes mellitus 1.700E-2 4.920E-2
2.260E-1
9.348E-1
 1 80
Show 14 more annotations

5: Mouse Phenotype [Display Chart] 7 input genes in category / 310 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0009108 increased pancreas weight 5.395E-8 1.672E-5 1.056E-4 1.672E-5 3 13
2 MP:0009107 abnormal pancreas weight 3.806E-7 5.049E-5 3.189E-4 1.180E-4 3 24
3 MP:0003450 enlarged pancreas 4.886E-7 5.049E-5 3.189E-4 1.515E-4 3 26
4 MP:0009854 impaired gastric peristalsis 1.095E-5 7.149E-4 4.515E-3 3.394E-3 2 8
5 MP:0009106 abnormal pancreas size 1.153E-5 7.149E-4 4.515E-3 3.574E-3 3 73
6 MP:0009343 dilated gallbladder 2.577E-5 1.180E-3 7.451E-3 7.989E-3 2 12
7 MP:0002693 abnormal pancreas physiology 2.735E-5 1.180E-3 7.451E-3 8.479E-3 4 315
8 MP:0008006 increased stomach pH 3.045E-5 1.180E-3 7.451E-3 9.439E-3 2 13
9 MP:0001664 abnormal digestion 4.290E-5 1.319E-3 8.329E-3 1.330E-2 3 113
10 MP:0008004 abnormal stomach pH 4.680E-5 1.319E-3 8.329E-3 1.451E-2 2 16
11 MP:0011895 abnormal circulating unsaturated transferrin level 4.680E-5 1.319E-3 8.329E-3 1.451E-2 2 16
12 MP:0011892 abnormal circulating transferrin level 5.963E-5 1.540E-3 9.728E-3 1.848E-2 2 18
13 MP:0004139 abnormal gastric parietal cell morphology 1.364E-4 3.253E-3 2.054E-2 4.228E-2 2 27
14 MP:0003892 abnormal gastric gland morphology 2.441E-4 5.405E-3 3.414E-2
7.567E-2
 2 36
15 MP:0005084 abnormal gallbladder morphology 2.722E-4 5.626E-3 3.553E-2
8.439E-2
 2 38
16 MP:0004981 decreased neuronal precursor cell number 5.310E-4 1.029E-2
6.497E-2
1.646E-1
 2 53
17 MP:0009156 absent pancreatic acini 6.760E-4 1.172E-2
7.402E-2
2.096E-1
 1 1
18 MP:0001777 abnormal body temperature homeostasis 6.805E-4 1.172E-2
7.402E-2
2.110E-1
 2 60
19 MP:0011082 abnormal gastrointestinal motility 7.984E-4 1.303E-2
8.227E-2
2.475E-1
 2 65
20 MP:0001944 abnormal pancreas morphology 1.211E-3 1.830E-2
1.156E-1
3.754E-1
 3 350
21 MP:0003917 increased kidney weight 1.268E-3 1.830E-2
1.156E-1
3.930E-1
 2 82
22 MP:0004979 abnormal neuronal precursor cell number 1.299E-3 1.830E-2
1.156E-1
4.026E-1
 2 83
23 MP:0010792 abnormal stomach mucosa morphology 1.426E-3 1.922E-2
1.214E-1
4.420E-1
 2 87
24 MP:0010783 abnormal stomach wall morphology 1.559E-3 1.975E-2
1.247E-1
4.832E-1
 2 91
25 MP:0004152 abnormal circulating iron level 1.593E-3 1.975E-2
1.247E-1
4.938E-1
 2 92
26 MP:0002646 increased intestinal cholesterol absorption 2.027E-3 2.094E-2
1.323E-1
6.283E-1
 1 3
27 MP:0003341 chronic pancreas inflammation 2.027E-3 2.094E-2
1.323E-1
6.283E-1
 1 3
28 MP:0011935 abnormal pancreatic bud formation 2.027E-3 2.094E-2
1.323E-1
6.283E-1
 1 3
29 MP:0003338 pancreas lipomatosis 2.027E-3 2.094E-2
1.323E-1
6.283E-1
 1 3
30 MP:0006002 abnormal small intestinal transit time 2.027E-3 2.094E-2
1.323E-1
6.283E-1
 1 3
31 MP:0005083 abnormal biliary tract morphology 2.108E-3 2.108E-2
1.331E-1
6.535E-1
 2 106
32 MP:0011891 decreased circulating ferritin level 2.702E-3 2.326E-2
1.469E-1
8.375E-1
 1 4
33 MP:0008107 absent horizontal cells 2.702E-3 2.326E-2
1.469E-1
8.375E-1
 1 4
34 MP:0009753 enhanced behavioral response to morphine 2.702E-3 2.326E-2
1.469E-1
8.375E-1
 1 4
35 MP:0008508 thick retinal ganglion layer 2.702E-3 2.326E-2
1.469E-1
8.375E-1
 1 4
36 MP:0010803 abnormal stomach enteroendocrine cell morphology 2.702E-3 2.326E-2
1.469E-1
8.375E-1
 1 4
37 MP:0005449 abnormal food intake 2.871E-3 2.405E-2
1.519E-1
8.899E-1
 3 472
38 MP:0011947 abnormal fluid intake 3.057E-3 2.468E-2
1.558E-1
9.477E-1
 2 128
39 MP:0001440 abnormal grooming behavior 3.104E-3 2.468E-2
1.558E-1
9.623E-1
 2 129
40 MP:0003655 absent pancreas 3.376E-3 2.553E-2
1.612E-1
1.000E0
 1 5
41 MP:0004138 abnormal mucous neck cell morphology 3.376E-3 2.553E-2
1.612E-1
1.000E0
 1 5
42 MP:0002707 abnormal kidney weight 3.697E-3 2.616E-2
1.652E-1
1.000E0
 2 141
43 MP:0001770 abnormal iron level 3.853E-3 2.616E-2
1.652E-1
1.000E0
 2 144
44 MP:0003068 enlarged kidney 3.905E-3 2.616E-2
1.652E-1
1.000E0
 2 145
45 MP:0002910 abnormal excitatory postsynaptic currents 3.958E-3 2.616E-2
1.652E-1
1.000E0
 2 146
46 MP:0008514 absent retinal inner plexiform layer 4.050E-3 2.616E-2
1.652E-1
1.000E0
 1 6
47 MP:0006095 absent amacrine cells 4.050E-3 2.616E-2
1.652E-1
1.000E0
 1 6
48 MP:0011934 abnormal branching involved in pancreas development 4.050E-3 2.616E-2
1.652E-1
1.000E0
 1 6
49 MP:0005637 abnormal iron homeostasis 4.173E-3 2.640E-2
1.667E-1
1.000E0
 2 150
50 MP:0001422 abnormal drinking behavior 4.283E-3 2.655E-2
1.677E-1
1.000E0
 2 152
Show 45 more annotations

6: Domain [Display Chart] 7 input genes in category / 23 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS00259 GASTRIN PROSITE 1.197E-7 5.505E-7 2.056E-6 2.752E-6 2 2
2 PF00918 Gastrin Pfam 1.197E-7 5.505E-7 2.056E-6 2.752E-6 2 2
3 IPR009126 Cholcskin rcpt InterPro 1.197E-7 5.505E-7 2.056E-6 2.752E-6 2 2
4 IPR001651 Gastrin InterPro 1.197E-7 5.505E-7 2.056E-6 2.752E-6 2 2
5 IPR013152 Gastrin/cholecystokinin CS InterPro 1.197E-7 5.505E-7 2.056E-6 2.752E-6 2 2
6 PF09193 CholecysA-Rec N Pfam 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
7 IPR001560 Bombesin rcpt 3 InterPro 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
8 IPR000314 Gastrin rcpt InterPro 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
9 IPR000596 Cholcy rcpt A InterPro 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
10 4.10.670.10 - Gene3D 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
11 IPR015499 CCK-like InterPro 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
12 IPR015276 CholecystokininA recpt N InterPro 3.736E-4 7.161E-4 2.674E-3 8.594E-3 1 1
13 SM01381 7TM GPCR Srsx SMART 7.294E-4 1.011E-3 3.775E-3 1.678E-2 2 112
14 PS00257 BOMBESIN PROSITE 7.471E-4 1.011E-3 3.775E-3 1.718E-2 1 2
15 IPR015674 Gastrin-RP InterPro 7.471E-4 1.011E-3 3.775E-3 1.718E-2 1 2
16 IPR000874 Bombesin InterPro 7.471E-4 1.011E-3 3.775E-3 1.718E-2 1 2
17 PF02044 Bombesin Pfam 7.471E-4 1.011E-3 3.775E-3 1.718E-2 1 2
18 IPR001556 Bombsn rcpt-like InterPro 1.121E-3 1.432E-3 5.347E-3 2.577E-2 1 3
19 4.10.280.10 - Gene3D 4.003E-2 4.363E-2
1.629E-1
9.206E-1
 1 109
20 PF00010 HLH Pfam 4.111E-2 4.363E-2
1.629E-1
9.455E-1
 1 112
21 SM00353 HLH SMART 4.291E-2 4.363E-2
1.629E-1
9.870E-1
 1 117
22 PS50888 BHLH PROSITE 4.327E-2 4.363E-2
1.629E-1
9.952E-1
 1 118
23 IPR011598 bHLH dom InterPro 4.363E-2 4.363E-2
1.629E-1
1.000E0
 1 119
Show 18 more annotations

7: Pathway [Display Chart] 7 input genes in category / 31 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269578 G alpha (q) signalling events BioSystems: REACTOME 8.601E-11 2.666E-9 1.074E-8 2.666E-9 6 192
2 1269592 Gastrin-CREB signalling pathway via PKC and MAPK BioSystems: REACTOME 1.389E-8 1.577E-7 6.350E-7 4.305E-7 6 446
3 1269546 Peptide ligand-binding receptors BioSystems: REACTOME 1.526E-8 1.577E-7 6.350E-7 4.730E-7 5 188
4 1269545 Class A/1 (Rhodopsin-like receptors) BioSystems: REACTOME 2.258E-7 1.750E-6 7.049E-6 7.001E-6 5 322
5 1269544 GPCR ligand binding BioSystems: REACTOME 1.261E-6 7.817E-6 3.148E-5 3.908E-5 5 455
6 SMP00246 Pirenzepine Pathway SMPDB 3.671E-5 9.141E-5 3.681E-4 1.138E-3 2 17
7 SMP00229 Rabeprazole Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
8 SMP00227 Lansoprazole Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
9 SMP00228 Pantoprazole Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
10 SMP00226 Omeprazole Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
11 SMP00230 Ranitidine Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
12 SMP00225 Esomeprazole Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
13 SMP00231 Famotidine Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
14 SMP00233 Nizatidine Pathway SMPDB 4.128E-5 9.141E-5 3.681E-4 1.280E-3 2 18
15 83053 Neuroactive ligand-receptor interaction BioSystems: KEGG 3.607E-4 7.454E-4 3.002E-3 1.118E-2 3 278
16 154409 Gastric acid secretion BioSystems: KEGG 7.374E-4 1.429E-3 5.754E-3 2.286E-2 2 75
17 M599 PAC1 Receptor Pathway MSigDB C2 BIOCARTA (v6.0) 3.930E-3 7.167E-3 2.886E-2
1.218E-1
 1 7
18 83050 Calcium signaling pathway BioSystems: KEGG 4.253E-3 7.324E-3 2.950E-2
1.318E-1
 2 182
19 1270338 Regulation of gene expression in early pancreatic precursor cells BioSystems: REACTOME 4.490E-3 7.326E-3 2.951E-2
1.392E-1
 1 8
20 M14775 G alpha s Pathway MSigDB C2 BIOCARTA (v6.0) 8.964E-3 1.389E-2
5.595E-2
2.779E-1
 1 16
21 SMP00232 Cimetidine Pathway SMPDB 9.521E-3 1.406E-2
5.660E-2
2.952E-1
 1 17
22 1268751 Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) BioSystems: REACTOME 1.119E-2 1.577E-2
6.352E-2
3.470E-1
 1 20
23 1268750 Incretin synthesis, secretion, and inactivation BioSystems: REACTOME 1.286E-2 1.734E-2
6.982E-2
3.988E-1
 1 23
24 M2701 Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. MSigDB C2 BIOCARTA (v6.0) 1.509E-2 1.949E-2
7.847E-2
4.677E-1
 1 27
25 1270337 Regulation of beta-cell development BioSystems: REACTOME 1.841E-2 2.283E-2
9.194E-2
5.708E-1
 1 33
26 M19043 Adrenergic Pathway MSigDB C2 BIOCARTA (v6.0) 2.007E-2 2.393E-2
9.638E-2
6.222E-1
 1 36
27 M2579 Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway. MSigDB C2 BIOCARTA (v6.0) 2.503E-2 2.874E-2
1.158E-1
7.761E-1
 1 45
28 169347 Notch-mediated HES/HEY network BioSystems: Pathway Interaction Database 2.668E-2 2.954E-2
1.190E-1
8.272E-1
 1 48
Show 23 more annotations

8: Pubmed [Display Chart] 7 input genes in category / 1278 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 10536058 Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells. Pubmed 1.974E-15 2.523E-12 1.950E-11 2.523E-12 4 5
2 16754659 Stable association between G alpha(q) and phospholipase C beta 1 in living cells. Pubmed 1.790E-12 4.380E-10 3.386E-9 2.288E-9 5 95
3 7681836 The human brain cholecystokinin-B/gastrin receptor. Cloning and characterization. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
4 12198366 Investigation of quantitative trait loci in the CCKAR gene with susceptibility to alcoholism. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
5 20023595 Gene variations in the cholecystokinin system in patients with panic disorder. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
6 20732371 Association study of polymorphisms in cholecystokinin gene and its receptors with antipsychotic induced weight gain in schizophrenia patients. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
7 11368834 No association of CCK and CCK(B) receptor polymorphisms with alcohol dependence. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
8 15313848 Genetic polymorphisms in Parkinson disease subjects with and without hallucinations: an analysis of the cholecystokinin system. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
9 12777967 Cholecystokinin, cholecystokinin-A receptor and cholecystokinin-B receptor gene polymorphisms in Parkinson's disease. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
10 24576871 Expression of cholecystokinin, gastrin, and their receptors in the mouse cornea. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
11 8876222 G protein-coupled cholecystokinin-B/gastrin receptors are responsible for physiological cell growth of the stomach mucosa in vivo. Pubmed 3.770E-12 4.380E-10 3.386E-9 4.818E-9 3 3
12 17228339 Significant increase in the aggressive behavior of transgenic mice overexpressing peripheral progastrin peptides: associated changes in CCK2 and serotonin receptors in the CNS. Pubmed 1.508E-11 1.482E-9 1.146E-8 1.927E-8 3 4
13 26948890 Cerebellar Transcriptome Profiles of ATXN1 Transgenic Mice Reveal SCA1 Disease Progression and Protection Pathways. Pubmed 1.508E-11 1.482E-9 1.146E-8 1.927E-8 3 4
14 15152034 Cholecystokinin modulates migration of gonadotropin-releasing hormone-1 neurons. Pubmed 2.110E-10 1.926E-8 1.489E-7 2.697E-7 3 8
15 26169832 Islet Cells Serve as Cells of Origin of Pancreatic Gastrin-Positive Endocrine Tumors. Pubmed 1.714E-9 1.460E-7 1.129E-6 2.190E-6 3 15
16 11278902 Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity. Pubmed 3.072E-9 2.454E-7 1.897E-6 3.927E-6 3 18
17 18721803 A transcriptional network coordinately determines transmitter and peptidergic fate in the dorsal spinal cord. Pubmed 5.007E-9 3.764E-7 2.910E-6 6.398E-6 3 21
18 25875176 Functional synergy between cholecystokinin receptors CCKAR and CCKBR in mammalian brain development. Pubmed 5.797E-9 4.116E-7 3.182E-6 7.408E-6 3 22
19 20468064 Association study of 182 candidate genes in anorexia nervosa. Pubmed 1.727E-8 5.333E-7 4.123E-6 2.207E-5 4 182
20 15178543 Absence of the cholecystokinin-A receptor deteriorates homeostasis of body temperature in response to changes in ambient temperature. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
21 23043971 Behavioral and cortical EEG evaluations confirm the roles of both CCKA and CCKB receptors in mouse CCK-induced anxiety. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
22 17105752 Transcriptional profiling of gastrin-regulated genes in mouse stomach. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
23 22010007 Profiling CCK-mediated pancreatic growth: the dynamic genetic program and the role of STATs as potential regulators. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
24 3011648 The genes for human gastrin and cholecystokinin are located on different chromosomes. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
25 26508021 Expression of cholecystokinin receptors in colon cancer and the clinical correlation in Taiwan. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
26 25160855 Gene expression profiling of gastric mucosa in mice lacking CCK and gastrin receptors. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
27 16093397 Cholecystokinin activates orexin/hypocretin neurons through the cholecystokinin A receptor. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
28 19760980 779 TC of CCK-1 intron 1 is associated with postprandial syndrome (PDS) in Japanese male subjects. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
29 9006937 Identification of two amino acids of the human cholecystokinin-A receptor that interact with the N-terminal moiety of cholecystokinin. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
30 9603948 Met-195 of the cholecystokinin-A receptor interacts with the sulfated tyrosine of cholecystokinin and is crucial for receptor transition to high affinity state. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
31 16228228 Expression of gastrin and its receptor in human gastric cancer tissues. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
32 11925470 Energy metabolism and turnover are increased in mice lacking the cholecystokinin-B receptor. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
33 24914377 Investigation of cholecystokinin receptors in the human lower esophageal sphincter. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
34 15040018 Coexpression of cholecystokinin-B/gastrin receptor and gastrin gene in human gastric tissues and gastric cancer cell line. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
35 14762785 Altered control of gastric acid secretion in gastrin-cholecystokinin double mutant mice. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
36 8343165 Molecular cloning, functional expression and chromosomal localization of the human cholecystokinin type A receptor. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
37 10595537 Arginine 197 of the cholecystokinin-A receptor binding site interacts with the sulfate of the peptide agonist cholecystokinin. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
38 15100163 Involvement of endogenous CCK and CCK1 receptors in colonic motor function. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
39 20932834 Gastrin increases its own synthesis in gastrointestinal cancer cells via the CCK2 receptor. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
40 21186400 Role of endogenous cholecystokinin on growth of human pancreatic cancer. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
41 15001692 In vitro and in vivo evaluation of 111In-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
42 15740988 Cholecystokinin (CCK) and the CCKA receptor gene polymorphism, and smoking behavior. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
43 30115027 Low serum gastrin associated with ER Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
44 11300760 Intermolecular interactions between cholecystokinin-8 and the third extracellular loop of the cholecystokinin A receptor. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
45 21652729 Gastrin-deficient mice have disturbed hematopoiesis in response to iron deficiency. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
46 10400673 Arginine 336 and asparagine 333 of the human cholecystokinin-A receptor binding site interact with the penultimate aspartic acid and the C-terminal amide of cholecystokinin. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
47 15520004 Distinct molecular mechanisms for agonist peptide binding to types A and B cholecystokinin receptors demonstrated using fluorescence spectroscopy. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
48 15354400 Cholecystokinin- and cholecystokinin-B-receptor gene polymorphisms in panic disorder. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
49 12189558 Potential role of endocrine gastrin in the colonic adenoma carcinoma sequence. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
50 27072272 Heterogeneous expression of cholecystokinin and gastrin receptor in stomach and pancreatic cancer: An immunohistochemical study. Pubmed 2.879E-8 5.333E-7 4.123E-6 3.680E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 6 input genes in category / 49 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CCKAR CCKAR interactions 2.163E-11 1.060E-9 4.748E-9 1.060E-9 3 3
2 int:CCK CCK interactions 7.568E-10 1.854E-8 8.305E-8 3.708E-8 3 7
3 int:CCKBR CCKBR interactions 7.863E-9 9.633E-8 4.315E-7 3.853E-7 3 14
4 int:MEP1B MEP1B interactions 7.863E-9 9.633E-8 4.315E-7 3.853E-7 3 14
5 int:MEP1A MEP1A interactions 2.414E-5 2.366E-4 1.060E-3 1.183E-3 2 23
6 int:CPE CPE interactions 3.871E-5 3.161E-4 1.416E-3 1.897E-3 2 29
7 int:RBPJL RBPJL interactions 1.355E-3 9.221E-3 4.130E-2
6.640E-2
 1 4
8 int:GRP GRP interactions 1.694E-3 9.221E-3 4.130E-2
8.299E-2
 1 5
9 int:ENPEP ENPEP interactions 1.694E-3 9.221E-3 4.130E-2
8.299E-2
 1 5
10 int:CROCCP2 CROCCP2 interactions 2.032E-3 9.957E-3 4.460E-2
9.957E-2
 1 6
11 int:CCDC27 CCDC27 interactions 2.370E-3 1.056E-2 4.730E-2
1.162E-1
 1 7
12 int:SPATA7 SPATA7 interactions 3.385E-3 1.382E-2
6.191E-2
1.659E-1
 1 10
13 int:PTF1A PTF1A interactions 5.074E-3 1.560E-2
6.986E-2
2.486E-1
 1 15
14 int:GAST GAST interactions 5.074E-3 1.560E-2
6.986E-2
2.486E-1
 1 15
15 int:NTM NTM interactions 5.411E-3 1.560E-2
6.986E-2
2.652E-1
 1 16
16 int:PXK PXK interactions 5.411E-3 1.560E-2
6.986E-2
2.652E-1
 1 16
17 int:XAGE3 XAGE3 interactions 5.411E-3 1.560E-2
6.986E-2
2.652E-1
 1 16
18 int:CP CP interactions 5.749E-3 1.565E-2
7.010E-2
2.817E-1
 1 17
19 int:DPP4 DPP4 interactions 7.771E-3 2.004E-2
8.977E-2
3.808E-1
 1 23
20 int:ZER1 ZER1 interactions 9.454E-3 2.181E-2
9.767E-2
4.632E-1
 1 28
21 int:KIRREL1 KIRREL1 interactions 9.790E-3 2.181E-2
9.767E-2
4.797E-1
 1 29
22 int:ATE1 ATE1 interactions 9.790E-3 2.181E-2
9.767E-2
4.797E-1
 1 29
23 int:AAMP AAMP interactions 1.181E-2 2.515E-2
1.127E-1
5.785E-1
 1 35
24 int:PCDHB16 PCDHB16 interactions 1.248E-2 2.547E-2
1.141E-1
6.114E-1
 1 37
25 int:BCAR3 BCAR3 interactions 1.315E-2 2.577E-2
1.154E-1
6.442E-1
 1 39
26 int:THADA THADA interactions 1.516E-2 2.713E-2
1.215E-1
7.427E-1
 1 45
27 int:NME2P1 NME2P1 interactions 1.549E-2 2.713E-2
1.215E-1
7.591E-1
 1 46
28 int:PRKAB1 PRKAB1 interactions 1.683E-2 2.713E-2
1.215E-1
8.246E-1
 1 50
29 int:HECTD3 HECTD3 interactions 1.683E-2 2.713E-2
1.215E-1
8.246E-1
 1 50
30 int:PRKAG1 PRKAG1 interactions 1.683E-2 2.713E-2
1.215E-1
8.246E-1
 1 50
31 int:ZW10 ZW10 interactions 1.716E-2 2.713E-2
1.215E-1
8.410E-1
 1 51
32 int:GRPR GRPR interactions 1.817E-2 2.782E-2
1.246E-1
8.901E-1
 1 54
33 int:ZZEF1 ZZEF1 interactions 1.950E-2 2.895E-2
1.297E-1
9.555E-1
 1 58
34 int:RPGRIP1 RPGRIP1 interactions 2.083E-2 3.002E-2
1.345E-1
1.000E0
 1 62
35 int:TRIP12 TRIP12 interactions 2.250E-2 3.107E-2
1.392E-1
1.000E0
 1 67
36 int:ATP13A2 ATP13A2 interactions 2.283E-2 3.107E-2
1.392E-1
1.000E0
 1 68
37 int:TCF12 TCF12 interactions 2.946E-2 3.902E-2
1.748E-1
1.000E0
 1 88
38 int:CCNDBP1 CCNDBP1 interactions 3.177E-2 4.097E-2
1.835E-1
1.000E0
 1 95
39 int:GMCL1 GMCL1 interactions 3.540E-2 4.447E-2
1.992E-1
1.000E0
 1 106
40 int:MME MME interactions 3.704E-2 4.538E-2
2.032E-1
1.000E0
 1 111
Show 35 more annotations

10: Cytoband [Display Chart] 7 input genes in category / 7 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 4p15.1-p15.2 4p15.1-p15.2 2.020E-4 7.068E-4 1.833E-3 1.414E-3 1 1
2 18q21.1-q21.32 18q21.1-q21.32 2.020E-4 7.068E-4 1.833E-3 1.414E-3 1 1
3 10p12.2 10p12.2 2.220E-3 5.179E-3 1.343E-2 1.554E-2 1 11
4 3p22.1 3p22.1 8.653E-3 1.514E-2 3.926E-2
6.057E-2
 1 43
5 17q21 17q21 1.266E-2 1.639E-2 4.251E-2
8.859E-2
 1 63
6 Xq26.3 Xq26.3 1.405E-2 1.639E-2 4.251E-2
9.837E-2
 1 70
7 11p15.4 11p15.4 4.087E-2 4.087E-2
1.060E-1
2.861E-1
 1 206
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 38 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 7 input genes in category / 4 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 224 Cholecystokinin receptors genenames.org 1.269E-7 5.075E-7 1.057E-6 5.075E-7 2 2
2 542 Endogenous ligands genenames.org 7.349E-5 1.470E-4 3.062E-4 2.940E-4 3 237
3 222 Bombesin receptors genenames.org 1.154E-3 1.538E-3 3.205E-3 4.615E-3 1 3
4 420 Basic helix-loop-helix proteins genenames.org 4.157E-2 4.157E-2
8.660E-2
1.663E-1
 1 110

13: Coexpression [Display Chart] 7 input genes in category / 331 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M1954 Genes with high-CpG-density promoters (HCP) bearing the tri-methylation mark at H3K27 (H3K27me3) in MCV6 cells (embryonic fibroblasts trapped in a differentiated state). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.087E-6 1.353E-3 8.632E-3 1.353E-3 4 434
2 M5392 Genes up-regulated in NIH3T3 cells (fibroblasts) after treatment with Y27632 [PubChem=123862], an inhibitor of ROCK proteins; the changes did not depend on expression of constitutively active (Q63L) form of RHOA [GeneID=387]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.173E-5 5.252E-3 3.351E-2 1.050E-2 2 29
3 20460173-ImmPortCytokines Human Immune Kong10 456genes ImmPort Cytokines GeneSigDB 2.154E-4 2.377E-2
1.517E-1
7.131E-2
 3 433
4 M2808 Genes up-regulated in neurons. MSigDB C6: Oncogenic Signatures (v6.0) 3.829E-4 2.689E-2
1.716E-1
1.268E-1
 2 100
5 15888489-Table1 Mouse Brain Chung05 134genes GeneSigDB 4.062E-4 2.689E-2
1.716E-1
1.345E-1
 2 103
6 M2740 Genes down-regulated in TIG3 cells (fibroblasts) upon knockdown of SUZ12 [Gene ID=23512] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.343E-3 4.566E-2
2.913E-1
4.444E-1
 2 188
7 M7666 Genes up-regulated in ex vivo follicular dendritic cells: peripheral lymph node versus Peyers patch. MSigDB C7: Immunologic Signatures (v6.0) 1.488E-3 4.566E-2
2.913E-1
4.924E-1
 2 198
8 M5208 Genes down-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to T. gondii. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 4.566E-2
2.913E-1
4.973E-1
 2 199
9 M5214 Genes down-regulated in comparison of dendritic cells (DC) exposed to L. major versus DCs exposed to M. tuberculosis. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 4.566E-2
2.913E-1
4.973E-1
 2 199
10 M4335 Genes up-regulated in comparison of TregCD103-Klrg1- versus TregCD103+Klrg1- (see Table 1S in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 4.566E-2
2.913E-1
5.023E-1
 2 200
11 M3605 Genes up-regulated in comparison of CD8 T cells at 0 h versus those at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 4.566E-2
2.913E-1
5.023E-1
 2 200
Show 6 more annotations

14: Coexpression Atlas [Display Chart] 7 input genes in category / 350 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 stomach stomach Human Protein Atlas 1.324E-5 2.624E-3 1.689E-2 4.633E-3 3 160
2 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup1/Slc17a6 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup1/Slc17a6 BrainMap 1.702E-5 2.624E-3 1.689E-2 5.956E-3 3 174
3 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Overall Top 200 Genes BrainMap 2.249E-5 2.624E-3 1.689E-2 7.872E-3 3 191
4 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup4 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup4 Top 200 Genes BrainMap 6.596E-5 5.771E-3 3.715E-2 2.309E-2 3 274
5 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Subtype Excitatory.subGroup4 FrontalCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Subtype Excitatory.subGroup4 FrontalCortex Top 200 Genes BrainMap 1.105E-4 6.504E-3 4.186E-2 3.867E-2 3 326
6 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Subtype Excitatory.subGroup4 PosteriorCortex Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Subtype Excitatory.subGroup4 PosteriorCortex Top 200 Genes BrainMap 1.115E-4 6.504E-3 4.186E-2 3.902E-2 3 327
7 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Subtype Excitatory.subGroup4 Hippocampus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup4 Excitatory.subGroup4 Subtype Excitatory.subGroup4 Hippocampus Top 200 Genes BrainMap 1.307E-4 6.534E-3 4.205E-2 4.574E-2 3 345
8 pancreas pancreas Human Protein Atlas 2.107E-4 8.850E-3
5.696E-2
7.374E-2
 2 70
9 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Pancreas/pancreatic acinar cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Pancreas/pancreatic acinar cell Tabula Muris Consortium 3.330E-4 8.850E-3
5.696E-2
1.166E-1
 2 88
10 PCBC MESO-5 blastocyst 500 Progenitor-Cell-Biology-Consortium induced-Mesoderm fromBlastocyst-derived-humanEmbryonicStemCells top-relative-expression-ranked 500 PCBC 3.526E-4 8.850E-3
5.696E-2
1.234E-1
 3 483
11 PCBC MESO-5 fibroblast 500 Progenitor-Cell-Biology-Consortium induced-Mesoderm from inducedPluripotentialStemCells derived from from fibroblast top-relative-expression-ranked 500 PCBC 3.745E-4 8.850E-3
5.696E-2
1.311E-1
 3 493
12 PCBC MESO-5 500 Progenitor-Cell-Biology-Consortium induced-Mesoderm top-relative-expression-ranked 500 PCBC 3.768E-4 8.850E-3
5.696E-2
1.319E-1
 3 494
13 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Polydendrocyte/Polydendrocyte/Bmp4 C1q/Tnr//Tmsb4x BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Polydendrocyte/Polydendrocyte/Bmp4 C1q/Tnr//Tmsb4x BrainMap 3.799E-4 8.850E-3
5.696E-2
1.330E-1
 2 94
14 PCBC MESO-5 100 Progenitor-Cell-Biology-Consortium induced-Mesoderm top-relative-expression-ranked 100 PCBC 4.213E-4 8.850E-3
5.696E-2
1.475E-1
 2 99
15 PCBC MESO-5 fibroblast 100 Progenitor-Cell-Biology-Consortium induced-Mesoderm from inducedPluripotentialStemCells derived from from fibroblast top-relative-expression-ranked 100 PCBC 4.213E-4 8.850E-3
5.696E-2
1.475E-1
 2 99
16 PCBC ratio MESO-5 vs SC 100 ratio induced-Mesoderm vs StemCell top-relative-expression-ranked 100 PCBC 4.213E-4 8.850E-3
5.696E-2
1.475E-1
 2 99
17 PCBC ECTO 100 Progenitor-Cell-Biology-Consortium induced-Ectoderm top-relative-expression-ranked 100 PCBC 4.298E-4 8.850E-3
5.696E-2
1.504E-1
 2 100
18 Sample Type by Project: Shred 1/TCGA-Stomach/Stomach Adenocarcinoma/Stomach Adenocarcinoma - NOS/0 Sample Type by Project: Shred 1/TCGA-Stomach/Stomach Adenocarcinoma/Stomach Adenocarcinoma - NOS/0 TCGA-Stomach 6.598E-4 1.283E-2
8.258E-2
2.309E-1
 2 124
19 Sample Type by Project: Shred 1/TCGA-Pancreas/Pancreatic Adenocarcinoma/Colloid (Mucinous Noncystic) Carcinoma/4 Sample Type by Project: Shred 1/TCGA-Pancreas/Pancreatic Adenocarcinoma/Colloid (Mucinous Noncystic) Carcinoma/4 TCGA-Pancreas 7.137E-4 1.315E-2
8.463E-2
2.498E-1
 2 129
20 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Oligodendrocyte/Oligodendrocyte/Pdgfa-hi oligodendrocytes/Tnf BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Oligodendrocyte/Oligodendrocyte/Pdgfa-hi oligodendrocytes/Tnf BrainMap 7.584E-4 1.327E-2
8.543E-2
2.654E-1
 2 133
21 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Squamous Cell Carcinoma/3/0 Sample Type by Project: Shred 1/TCGA-Lung/Lung Carcinoma/Lung Squamous Cell Carcinoma/3/0 TCGA-Lung 9.503E-4 1.445E-2
9.303E-2
3.326E-1
 2 149
22 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup5/Syt6 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup5/Syt6 BrainMap 1.081E-3 1.445E-2
9.303E-2
3.783E-1
 2 159
23 Sample Type by Project: Shred 1/TCGA-Esophagus/Esophageal Carcinoma/Adenocarcinoma/1/0 Sample Type by Project: Shred 1/TCGA-Esophagus/Esophageal Carcinoma/Adenocarcinoma/1/0 TCGA-Esophagus 1.122E-3 1.445E-2
9.303E-2
3.926E-1
 2 162
24 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup4/Grp BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory/subGroup4/Grp BrainMap 1.263E-3 1.445E-2
9.303E-2
4.421E-1
 2 172
25 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Cpne5 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup2/Cpne5 BrainMap 1.337E-3 1.445E-2
9.303E-2
4.678E-1
 2 177
26 BrainMap BrainAtlas - Mouse McCarroll PosteriorCortex PosteriorCortex Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll PosteriorCortex PosteriorCortex Overall Top 200 Genes BrainMap 1.459E-3 1.445E-2
9.303E-2
5.106E-1
 2 185
27 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup6 Excitatory.subGroup6 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup6 Excitatory.subGroup6 Overall Top 200 Genes BrainMap 1.506E-3 1.445E-2
9.303E-2
5.271E-1
 2 188
28 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup2 Excitatory.subGroup2 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup2 Excitatory.subGroup2 Overall Top 200 Genes BrainMap 1.506E-3 1.445E-2
9.303E-2
5.271E-1
 2 188
29 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup6 Excitatory.subGroup6 Top 200 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup6 Excitatory.subGroup6 Top 200 BrainMap 1.506E-3 1.445E-2
9.303E-2
5.271E-1
 2 188
30 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory.Slc17a7,Slc17a6 Neuron.excitatory.Slc17a7,Slc17a6 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory.Slc17a7,Slc17a6 Neuron.excitatory.Slc17a7,Slc17a6 Overall Top 200 Genes BrainMap 1.506E-3 1.445E-2
9.303E-2
5.271E-1
 2 188
31 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory.Slc17a7,Slc17a6 Neuron.excitatory.Slc17a7,Slc17a6 Top 200 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory.Slc17a7,Slc17a6 Neuron.excitatory.Slc17a7,Slc17a6 Top 200 BrainMap 1.506E-3 1.445E-2
9.303E-2
5.271E-1
 2 188
32 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/mixed excitatory BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/mixed excitatory BrainMap 1.538E-3 1.445E-2
9.303E-2
5.382E-1
 2 190
33 BrainMap BrainAtlas - Mouse McCarroll FrontalCortex FrontalCortex Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll FrontalCortex FrontalCortex Overall Top 200 Genes BrainMap 1.538E-3 1.445E-2
9.303E-2
5.382E-1
 2 190
34 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/excitatory BrainMap 1.570E-3 1.445E-2
9.303E-2
5.495E-1
 2 192
35 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligoastrocytoma/4 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligoastrocytoma/4 TCGA-Brain 1.602E-3 1.445E-2
9.303E-2
5.608E-1
 2 194
36 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Astrocytoma/4 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Astrocytoma/4 TCGA-Brain 1.602E-3 1.445E-2
9.303E-2
5.608E-1
 2 194
37 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup3 Excitatory.subGroup3 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup3 Excitatory.subGroup3 Overall Top 200 Genes BrainMap 1.635E-3 1.445E-2
9.303E-2
5.723E-1
 2 196
38 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup3 Excitatory.subGroup3 Top 200 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup3 Excitatory.subGroup3 Top 200 BrainMap 1.635E-3 1.445E-2
9.303E-2
5.723E-1
 2 196
39 BrainMap BrainAtlas - Mouse McCarroll Hippocampus Hippocampus Top 200 BrainMap BrainAtlas - Mouse McCarroll Hippocampus Hippocampus Top 200 BrainMap 1.652E-3 1.445E-2
9.303E-2
5.781E-1
 2 197
40 BrainMap BrainAtlas - Mouse McCarroll Hippocampus Hippocampus Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Hippocampus Hippocampus Overall Top 200 Genes BrainMap 1.652E-3 1.445E-2
9.303E-2
5.781E-1
 2 197
41 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Oligodendrocyte/Oligodendrocyte/Pdgfa-hi oligodendrocytes/Tnf//Kif5b BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Oligodendrocyte/Oligodendrocyte/Pdgfa-hi oligodendrocytes/Tnf//Kif5b BrainMap 1.923E-3 1.641E-2
1.056E-1
6.730E-1
 1 6
42 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex BrainMap 2.883E-3 2.393E-2
1.540E-1
1.000E0
 1 9
43 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup5 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup5 Top 200 Genes BrainMap 2.940E-3 2.393E-2
1.540E-1
1.000E0
 2 264
44 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup6 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup6 Top 200 Genes BrainMap 3.117E-3 2.480E-2
1.596E-1
1.000E0
 2 272
45 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Hippocampus BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Hippocampus BrainMap 3.203E-3 2.491E-2
1.603E-1
1.000E0
 1 10
46 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup3 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Excitatory.subGroup3 Top 200 Genes BrainMap 3.369E-3 2.564E-2
1.650E-1
1.000E0
 2 283
47 BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup2 Excitatory.subGroup2 Subtype Excitatory.subGroup2 GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Excitatory.subGroup2 Excitatory.subGroup2 Subtype Excitatory.subGroup2 GlobusPallidus Top 200 Genes BrainMap 3.582E-3 2.668E-2
1.717E-1
1.000E0
 2 292
48 ratio MESO vs SC 500 K1 ratio induced-Mesoderm vs StemCell top-relative-expression-ranked 500 k-means-cluster#1 PCBC 3.703E-3 2.698E-2
1.737E-1
1.000E0
 2 297
49 ratio DE vs SC 500 K5 ratio induced-DefinitiveEndoderm vs StemCell top-relative-expression-ranked 500 k-means-cluster#5 PCBC 3.777E-3 2.698E-2
1.737E-1
1.000E0
 2 300
50 BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Neuron.excitatory.Slc17a7 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neuron.excitatory Neuron.excitatory Subtype Neuron.excitatory.Slc17a7 Top 200 Genes BrainMap 4.104E-3 2.801E-2
1.803E-1
1.000E0
 2 313
Show 45 more annotations

15: Computational [Display Chart] 6 input genes in category / 32 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 7 input genes in category / 35 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-6505-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.028E-3 4.415E-2
1.831E-1
1.760E-1
 1 52
2 hsa-miR-556-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 4.415E-2
1.831E-1
1.827E-1
 1 54
3 hsa-miR-617:Non-Functional MTI Non-Functional MTI miRTarbase 5.221E-3 4.415E-2
1.831E-1
1.827E-1
 1 54
4 CAGCACT,MIR-512-3P:MSigDB CAGCACT,MIR-512-3P:MSigDB MSigDB 1.425E-2 4.415E-2
1.831E-1
4.989E-1
 1 148
5 hsa-miR-152-3p:Functional MTI Functional MTI miRTarbase 1.521E-2 4.415E-2
1.831E-1
5.324E-1
 1 158
6 hsa-miR-146a:PITA hsa-miR-146a:PITA TOP PITA 1.645E-2 4.415E-2
1.831E-1
5.759E-1
 1 171
7 hsa-miR-146b-5p:PITA hsa-miR-146b-5p:PITA TOP PITA 1.645E-2 4.415E-2
1.831E-1
5.759E-1
 1 171
8 hsa-miR-6868-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.789E-2 4.415E-2
1.831E-1
6.260E-1
 1 186
9 ACTGAAA,MIR-30A-3P:MSigDB ACTGAAA,MIR-30A-3P:MSigDB MSigDB 1.817E-2 4.415E-2
1.831E-1
6.360E-1
 1 189
10 ACTGAAA,MIR-30E-3P:MSigDB ACTGAAA,MIR-30E-3P:MSigDB MSigDB 1.817E-2 4.415E-2
1.831E-1
6.360E-1
 1 189
11 hsa-miR-614:mirSVR highEffct hsa-miR-614:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.970E-2 4.415E-2
1.831E-1
6.894E-1
 1 205
12 hsa-miR-148a-3p:Functional MTI Functional MTI miRTarbase 2.046E-2 4.415E-2
1.831E-1
7.160E-1
 1 213
13 hsa-miR-6734-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.131E-2 4.415E-2
1.831E-1
7.460E-1
 1 222
14 hsa-miR-3667-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.160E-2 4.415E-2
1.831E-1
7.560E-1
 1 225
15 hsa-miR-7:PITA hsa-miR-7:PITA TOP PITA 2.217E-2 4.415E-2
1.831E-1
7.760E-1
 1 231
16 hsa-miR-600:PITA hsa-miR-600:PITA TOP PITA 2.388E-2 4.415E-2
1.831E-1
8.358E-1
 1 249
17 hsa-miR-1273c:mirSVR lowEffct hsa-miR-1273c:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.549E-2 4.415E-2
1.831E-1
8.923E-1
 1 266
18 hsa-miR-507:PITA hsa-miR-507:PITA TOP PITA 2.909E-2 4.415E-2
1.831E-1
1.000E0
 1 304
19 hsa-miR-557:PITA hsa-miR-557:PITA TOP PITA 2.909E-2 4.415E-2
1.831E-1
1.000E0
 1 304
20 hsa-miR-324-5p:mirSVR highEffct hsa-miR-324-5p:mirSVR conserved highEffect-0.5 MicroRNA.org 3.361E-2 4.415E-2
1.831E-1
1.000E0
 1 352
21 hsa-miR-6504-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.503E-2 4.415E-2
1.831E-1
1.000E0
 1 367
22 hsa-miR-34b:PITA hsa-miR-34b:PITA TOP PITA 3.615E-2 4.415E-2
1.831E-1
1.000E0
 1 379
23 AATGTGA,MIR-23B:MSigDB AATGTGA,MIR-23B:MSigDB MSigDB 3.775E-2 4.415E-2
1.831E-1
1.000E0
 1 396
24 AATGTGA,MIR-23A:MSigDB AATGTGA,MIR-23A:MSigDB MSigDB 3.775E-2 4.415E-2
1.831E-1
1.000E0
 1 396
25 hsa-miR-423-3p:mirSVR lowEffct hsa-miR-423-3p:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 3.794E-2 4.415E-2
1.831E-1
1.000E0
 1 398
26 hsa-miR-148b-3p:Functional MTI Functional MTI miRTarbase 3.840E-2 4.415E-2
1.831E-1
1.000E0
 1 403
27 hsa-miR-7-5p:TargetScan hsa-miR-7-5p TargetScan 3.859E-2 4.415E-2
1.831E-1
1.000E0
 1 405
28 hsa-miR-524-3p:mirSVR lowEffct hsa-miR-524-3p:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 3.859E-2 4.415E-2
1.831E-1
1.000E0
 1 405
29 hsa-miR-1234:mirSVR lowEffct hsa-miR-1234:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.028E-2 4.415E-2
1.831E-1
1.000E0
 1 423
30 hsa-miR-525-3p:mirSVR lowEffct hsa-miR-525-3p:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.093E-2 4.415E-2
1.831E-1
1.000E0
 1 430
31 hsa-miR-448:PITA hsa-miR-448:PITA TOP PITA 4.168E-2 4.415E-2
1.831E-1
1.000E0
 1 438
32 hsa-miR-609:mirSVR highEffct hsa-miR-609:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.205E-2 4.415E-2
1.831E-1
1.000E0
 1 442
33 hsa-miR-1914:mirSVR highEffct hsa-miR-1914:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.271E-2 4.415E-2
1.831E-1
1.000E0
 1 449
34 hsa-miR-555:mirSVR highEffct hsa-miR-555:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.289E-2 4.415E-2
1.831E-1
1.000E0
 1 451
35 hsa-miR-210:mirSVR lowEffct hsa-miR-210:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 4.643E-2 4.643E-2
1.925E-1
1.000E0
 1 489
Show 30 more annotations

17: Drug [Display Chart] 7 input genes in category / 1922 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID005487260 Rc 3100 Stitch 9.944E-22 1.911E-18 1.555E-17 1.911E-18 6 8
2 CID000122127 Rc-3095 Stitch 2.107E-17 1.455E-14 1.184E-13 4.050E-14 6 30
3 CID000065987 spiroglumide Stitch 2.270E-17 1.455E-14 1.184E-13 4.364E-14 5 8
4 CID000104929 L-365,260 Stitch 8.247E-17 3.272E-14 2.663E-13 1.585E-13 6 37
5 CID000168356 glutaramic acid Stitch 1.022E-16 3.272E-14 2.663E-13 1.963E-13 5 10
6 CID003038479 AC1MI4X0 Stitch 1.022E-16 3.272E-14 2.663E-13 1.963E-13 5 10
7 CID005486814 Neuromedin C Stitch 1.362E-16 3.738E-14 3.042E-13 2.617E-13 6 40
8 CID005487263 Ici 216140 Stitch 3.210E-16 7.712E-14 6.277E-13 6.170E-13 5 12
9 CID000197533 L-368,935 Stitch 3.087E-15 6.592E-13 5.365E-12 5.933E-12 4 4
10 CID000122130 YM022 Stitch 1.067E-14 1.978E-12 1.609E-11 2.050E-11 5 22
11 CID006439313 A 70874 Stitch 1.543E-14 1.978E-12 1.609E-11 2.966E-11 4 5
12 CID000124911 AC1Q6XJ0 Stitch 1.543E-14 1.978E-12 1.609E-11 2.966E-11 4 5
13 CID003084441 Des(SO3)cck-8 Stitch 1.543E-14 1.978E-12 1.609E-11 2.966E-11 4 5
14 CID000065852 CR 1392 Stitch 1.543E-14 1.978E-12 1.609E-11 2.966E-11 4 5
15 CID006336097 MCI-727 Stitch 1.543E-14 1.978E-12 1.609E-11 2.966E-11 4 5
16 CID000108186 Ci988 Stitch 3.269E-14 3.926E-12 3.195E-11 6.282E-11 5 27
17 CID003082185 CCK-6 Stitch 4.629E-14 4.683E-12 3.811E-11 8.898E-11 4 6
18 CID006918156 A-71378 Stitch 4.629E-14 4.683E-12 3.811E-11 8.898E-11 4 6
19 CID000152221 Btlasp-NH2 Stitch 4.629E-14 4.683E-12 3.811E-11 8.898E-11 4 6
20 CID000003959 lorglumide Stitch 5.768E-14 5.543E-12 4.512E-11 1.109E-10 5 30
21 CID000060182 loxiglumide Stitch 6.877E-14 6.294E-12 5.123E-11 1.322E-10 5 31
22 CID003081775 Jmv 320 Stitch 1.080E-13 9.436E-12 7.680E-11 2.076E-10 4 7
23 CID000017268 Physalemin Stitch 1.314E-13 1.098E-11 8.934E-11 2.525E-10 5 35
24 CID000196737 Jmv 170 Stitch 2.160E-13 1.661E-11 1.351E-10 4.151E-10 4 8
25 CID000164107 Jmv 179 Stitch 2.160E-13 1.661E-11 1.351E-10 4.151E-10 4 8
26 CID000122118 PD135158 Stitch 6.479E-13 4.294E-11 3.494E-10 1.245E-9 4 10
27 CID000189058 Gastrin hexapeptide Stitch 6.479E-13 4.294E-11 3.494E-10 1.245E-9 4 10
28 CID003083069 Cionin Stitch 6.479E-13 4.294E-11 3.494E-10 1.245E-9 4 10
29 CID000443364 C11688 Stitch 6.479E-13 4.294E-11 3.494E-10 1.245E-9 4 10
30 CID006918209 KSG-504 Stitch 1.018E-12 6.522E-11 5.308E-10 1.957E-9 4 11
31 CID000121964 A71623 Stitch 2.205E-12 1.367E-10 1.113E-9 4.238E-9 4 13
32 CID000123661 CCK-7 Stitch 3.087E-12 1.854E-10 1.509E-9 5.933E-9 4 14
33 CID000356671 AC1L78W4 Stitch 4.209E-12 2.379E-10 1.936E-9 8.089E-9 4 15
34 CID003081446 CCK-5 Stitch 4.209E-12 2.379E-10 1.936E-9 8.089E-9 4 15
35 CID000163781 CCK-9 Stitch 5.611E-12 2.915E-10 2.372E-9 1.078E-8 4 16
36 CID000194097 H-Phe-NH2.HCl Stitch 5.611E-12 2.915E-10 2.372E-9 1.078E-8 4 16
37 CID003081599 Cck (26-33) Stitch 5.611E-12 2.915E-10 2.372E-9 1.078E-8 4 16
38 CID000122077 SR 27897 Stitch 7.337E-12 3.616E-10 2.943E-9 1.410E-8 4 17
39 CID000065813 AC1L240N Stitch 7.337E-12 3.616E-10 2.943E-9 1.410E-8 4 17
40 CID000021701 Peptavlon Stitch 8.515E-12 4.092E-10 3.330E-9 1.637E-8 5 78
41 CID000132980 L-740,093 Stitch 1.493E-11 6.514E-10 5.302E-9 2.870E-8 4 20
42 CID000128819 AC1Q6XIX Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
43 CID000132011 Ksg 504 Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
44 CID006444167 Jmv 332 Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
45 CID000128399 U-67827e Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
46 CID000097524 CBZ-cysteine Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
47 CID000170326 Snf 8815 Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
48 CID000196935 Pd 140376 Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
49 CID000126961 phenoxyacetylproglumide Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
50 CID000196789 A 57696 Stitch 1.763E-11 6.514E-10 5.302E-9 3.388E-8 3 3
Show 45 more annotations

18: Disease [Display Chart] 7 input genes in category / 271 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1868649 PANIC DISORDER 1 DisGeNET BeFree 1.631E-8 2.999E-6 1.854E-5 4.421E-6 4 77
2 C0030319 Panic Disorder DisGeNET Curated 2.213E-8 2.999E-6 1.854E-5 5.998E-6 4 83
3 C3640999 High Grade Astrocytic Tumor DisGeNET BeFree 1.599E-7 1.445E-5 8.931E-5 4.335E-5 2 2
4 C0346627 Intestinal Cancer DisGeNET BeFree 7.433E-7 5.036E-5 3.113E-4 2.014E-4 3 46
5 C0238462 Medullary carcinoma of thyroid DisGeNET Curated 1.483E-6 5.836E-5 3.608E-4 4.019E-4 4 236
6 C0206726 gliosarcoma DisGeNET Curated 1.508E-6 5.836E-5 3.608E-4 4.085E-4 3 58
7 C0796126 AICARDI-GOUTIERES SYNDROME 1 DisGeNET Curated 1.508E-6 5.836E-5 3.608E-4 4.085E-4 3 58
8 C0206754 Neuroendocrine Tumors DisGeNET Curated 1.927E-6 6.082E-5 3.759E-4 5.221E-4 4 252
9 C0685938 Malignant neoplasm of gastrointestinal tract DisGeNET BeFree 2.020E-6 6.082E-5 3.759E-4 5.473E-4 4 255
10 C0278701 Gastric Adenocarcinoma DisGeNET BeFree 5.236E-6 1.419E-4 8.771E-4 1.419E-3 4 324
11 C0003469 Anxiety Disorders DisGeNET Curated 1.006E-5 2.478E-4 1.532E-3 2.726E-3 4 382
12 C0003467 Anxiety DisGeNET Curated 1.636E-5 3.262E-4 2.016E-3 4.433E-3 4 432
13 C0043515 Zollinger-Ellison syndrome DisGeNET Curated 1.675E-5 3.262E-4 2.016E-3 4.539E-3 2 15
14 C0750952 Biliary Tract Cancer DisGeNET BeFree 1.685E-5 3.262E-4 2.016E-3 4.567E-3 3 129
15 C0007095 Carcinoid Tumor DisGeNET Curated 5.708E-5 1.031E-3 6.374E-3 1.547E-2 3 194
16 C0017150 Gastrinoma DisGeNET Curated 7.393E-5 1.252E-3 7.740E-3 2.004E-2 2 31
17 C1762616 Meningioma, benign, no ICD-O subtype DisGeNET BeFree 9.108E-5 1.452E-3 8.975E-3 2.468E-2 3 227
18 C0236663 Alcohol withdrawal syndrome DisGeNET Curated 1.238E-4 1.864E-3 1.152E-2 3.355E-2 2 40
19 C0238198 Gastrointestinal Stromal Tumors DisGeNET Curated 1.524E-4 2.173E-3 1.343E-2 4.129E-2 3 270
20 C0017178 Gastrointestinal Diseases DisGeNET Curated 1.940E-4 2.629E-3 1.625E-2
5.258E-2
 2 50
21 C0221026 X-linked agammaglobulinemia DisGeNET Curated 2.436E-4 3.144E-3 1.943E-2
6.601E-2
 2 56
22 C0018524 Hallucinations DisGeNET Curated 2.892E-4 3.451E-3 2.133E-2
7.837E-2
 2 61
23 C0086438 Hypogammaglobulinemia DisGeNET Curated 2.987E-4 3.451E-3 2.133E-2
8.096E-2
 2 62
24 C0281361 Adenocarcinoma of pancreas DisGeNET Curated 3.115E-4 3.451E-3 2.133E-2
8.442E-2
 3 344
25 C0947622 Cholecystolithiasis DisGeNET BeFree 3.184E-4 3.451E-3 2.133E-2
8.628E-2
 2 64
26 C0850572 Adenomatous polyp of colon DisGeNET BeFree 3.489E-4 3.547E-3 2.193E-2
9.456E-2
 2 67
27 C0238339 Hereditary pancreatitis DisGeNET Curated 4.030E-4 3.547E-3 2.193E-2
1.092E-1
 2 72
28 C0038358 Gastric ulcer DisGeNET Curated 4.257E-4 3.547E-3 2.193E-2
1.154E-1
 2 74
29 C4022808 Cerebellar agenesis DisGeNET BeFree 4.320E-4 3.547E-3 2.193E-2
1.171E-1
 1 1
30 cv:CN207621 Pancreatic agenesis 2 Clinical Variations 4.320E-4 3.547E-3 2.193E-2
1.171E-1
 1 1
31 cv:C1836780 Diabetes mellitus, permanent neonatal, with cerebellar agenesis Clinical Variations 4.320E-4 3.547E-3 2.193E-2
1.171E-1
 1 1
32 OMIN:609069 DIABETES MELLITUS, PERMANENT NEONATAL, WITH CEREBELLAR AGENESIS OMIM 4.320E-4 3.547E-3 2.193E-2
1.171E-1
 1 1
33 C0854145 Feeding Disorders DisGeNET BeFree 4.320E-4 3.547E-3 2.193E-2
1.171E-1
 1 1
34 C0001973 Alcoholic Intoxication, Chronic DisGeNET Curated 4.924E-4 3.925E-3 2.426E-2
1.334E-1
 3 402
35 C0025286 Meningioma DisGeNET Curated 5.179E-4 4.010E-3 2.479E-2
1.404E-1
 3 409
36 C0030297 Pancreatic Neoplasm DisGeNET Curated 6.245E-4 4.701E-3 2.906E-2
1.693E-1
 3 436
37 C0278727 Small cell lung cancer recurrent DisGeNET BeFree 8.638E-4 5.709E-3 3.529E-2
2.341E-1
 1 2
38 C0221219 Ectopic pancreas DisGeNET BeFree 8.638E-4 5.709E-3 3.529E-2
2.341E-1
 1 2
39 C1850096 Pancreatic Agenesis, Congenital DisGeNET Curated 8.638E-4 5.709E-3 3.529E-2
2.341E-1
 1 2
40 C1836780 PANCREATIC AND CEREBELLAR AGENESIS DisGeNET Curated 8.638E-4 5.709E-3 3.529E-2
2.341E-1
 1 2
41 C3891828 PANCREATIC AGENESIS 1 DisGeNET Curated 8.638E-4 5.709E-3 3.529E-2
2.341E-1
 1 2
42 C0008350 Cholelithiasis DisGeNET Curated 9.042E-4 5.834E-3 3.606E-2
2.450E-1
 2 108
43 C0333983 Hyperplastic Polyp DisGeNET BeFree 1.007E-3 6.201E-3 3.833E-2
2.728E-1
 2 114
44 C0262584 Carcinoma, Small Cell DisGeNET Curated 1.007E-3 6.201E-3 3.833E-2
2.728E-1
 2 114
45 C1301034 Pancreatic intraepithelial neoplasia DisGeNET BeFree 1.133E-3 6.824E-3 4.218E-2
3.071E-1
 2 121
46 C0017154 Gastritis, Atrophic DisGeNET Curated 1.189E-3 7.008E-3 4.332E-2
3.224E-1
 2 124
47 C0041657 Unconscious State DisGeNET Curated 1.295E-3 7.469E-3 4.617E-2
3.511E-1
 1 3
48 C0242216 Biliary calculi DisGeNET Curated 1.727E-3 9.750E-3
6.027E-2
4.680E-1
 1 4
49 C1292753 Primary Effusion Lymphoma DisGeNET BeFree 1.826E-3 1.010E-2
6.243E-2
4.949E-1
 2 154
50 C1654637 androgen independent prostate cancer DisGeNET BeFree 2.043E-3 1.026E-2
6.343E-2
5.536E-1
 2 163
Show 45 more annotations