1: GO: Molecular Function [Display Chart]
13 input genes in category / 90 annotations before applied cutoff / 18661 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
GO:0042626
|
ATPase activity, coupled to transmembrane movement of substances
|
|
4.314E-18
|
2.549E-16
|
1.296E-15
|
3.882E-16
|
9
|
110
|
2
|
GO:0015399
|
primary active transmembrane transporter activity
|
|
8.970E-18
|
2.549E-16
|
1.296E-15
|
8.073E-16
|
9
|
119
|
3
|
GO:0015405
|
P-P-bond-hydrolysis-driven transmembrane transporter activity
|
|
8.970E-18
|
2.549E-16
|
1.296E-15
|
8.073E-16
|
9
|
119
|
4
|
GO:0019829
|
cation-transporting ATPase activity
|
|
1.180E-17
|
2.549E-16
|
1.296E-15
|
1.062E-15
|
8
|
62
|
5
|
GO:0043492
|
ATPase activity, coupled to movement of substances
|
|
1.416E-17
|
2.549E-16
|
1.296E-15
|
1.275E-15
|
9
|
125
|
6
|
GO:0042625
|
ATPase coupled ion transmembrane transporter activity
|
|
5.243E-17
|
7.865E-16
|
3.997E-15
|
4.719E-15
|
8
|
74
|
7
|
GO:0015662
|
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
|
|
2.029E-16
|
2.609E-15
|
1.326E-14
|
1.827E-14
|
7
|
40
|
8
|
GO:0022853
|
active ion transmembrane transporter activity
|
|
6.298E-14
|
7.085E-13
|
3.601E-12
|
5.668E-12
|
8
|
175
|
9
|
GO:0042623
|
ATPase activity, coupled
|
|
1.077E-13
|
1.077E-12
|
5.474E-12
|
9.692E-12
|
9
|
332
|
10
|
GO:0022804
|
active transmembrane transporter activity
|
|
2.413E-13
|
2.172E-12
|
1.104E-11
|
2.172E-11
|
9
|
363
|
11
|
GO:0016887
|
ATPase activity
|
|
1.543E-12
|
1.263E-11
|
6.418E-11
|
1.389E-10
|
9
|
446
|
12
|
GO:0043682
|
copper-transporting ATPase activity
|
|
4.480E-7
|
2.983E-6
|
1.516E-5
|
4.032E-5
|
2
|
2
|
13
|
GO:0004008
|
copper-exporting ATPase activity
|
|
4.480E-7
|
2.983E-6
|
1.516E-5
|
4.032E-5
|
2
|
2
|
14
|
GO:0046961
|
proton-transporting ATPase activity, rotational mechanism
|
|
4.640E-7
|
2.983E-6
|
1.516E-5
|
4.176E-5
|
3
|
23
|
15
|
GO:0044769
|
ATPase activity, coupled to transmembrane movement of ions, rotational mechanism
|
|
6.021E-7
|
3.613E-6
|
1.836E-5
|
5.419E-5
|
3
|
25
|
16
|
GO:0036442
|
proton-exporting ATPase activity
|
|
9.550E-7
|
5.372E-6
|
2.730E-5
|
8.595E-5
|
3
|
29
|
17
|
GO:0046873
|
metal ion transmembrane transporter activity
|
|
6.701E-6
|
3.355E-5
|
1.705E-4
|
6.031E-4
|
5
|
426
|
18
|
GO:0005375
|
copper ion transmembrane transporter activity
|
|
6.709E-6
|
3.355E-5
|
1.705E-4
|
6.038E-4
|
2
|
6
|
19
|
GO:0005388
|
calcium-transporting ATPase activity
|
|
2.455E-5
|
1.163E-4
|
5.911E-4
|
2.210E-3
|
2
|
11
|
20
|
GO:0008553
|
proton-exporting ATPase activity, phosphorylative mechanism
|
|
2.945E-5
|
1.325E-4
|
6.736E-4
|
2.651E-3
|
2
|
12
|
21
|
GO:0015078
|
proton transmembrane transporter activity
|
|
5.313E-5
|
2.277E-4
|
1.157E-3
|
4.782E-3
|
3
|
109
|
22
|
GO:0015077
|
monovalent inorganic cation transmembrane transporter activity
|
|
9.939E-5
|
4.066E-4
|
2.067E-3
|
8.945E-3
|
4
|
375
|
23
|
GO:0046915
|
transition metal ion transmembrane transporter activity
|
|
3.797E-4
|
1.486E-3
|
7.552E-3
|
3.417E-2
|
2
|
42
|
24
|
GO:0036487
|
nitric-oxide synthase inhibitor activity
|
|
6.966E-4
|
2.612E-3
|
1.328E-2
|
6.270E-2
|
1
|
1
|
25
|
GO:0005507
|
copper ion binding
|
|
7.751E-4
|
2.790E-3
|
1.418E-2
|
6.976E-2
|
2
|
60
|
26
|
GO:0032767
|
copper-dependent protein binding
|
|
2.089E-3
|
6.713E-3
|
3.412E-2
|
1.880E-1
|
1
|
3
|
27
|
GO:0016509
|
long-chain-3-hydroxyacyl-CoA dehydrogenase activity
|
|
2.089E-3
|
6.713E-3
|
3.412E-2
|
1.880E-1
|
1
|
3
|
28
|
GO:0016532
|
superoxide dismutase copper chaperone activity
|
|
2.089E-3
|
6.713E-3
|
3.412E-2
|
1.880E-1
|
1
|
3
|
29
|
GO:0016508
|
long-chain-enoyl-CoA hydratase activity
|
|
2.784E-3
|
8.640E-3
|
4.391E-2
|
2.505E-1
|
1
|
4
|
30
|
GO:0004300
|
enoyl-CoA hydratase activity
|
|
3.479E-3
|
1.010E-2
|
5.133E-2
|
3.131E-1
|
1
|
5
|
31
|
GO:0016531
|
copper chaperone activity
|
|
3.479E-3
|
1.010E-2
|
5.133E-2
|
3.131E-1
|
1
|
5
|
32
|
GO:0015085
|
calcium ion transmembrane transporter activity
|
|
3.681E-3
|
1.035E-2
|
5.261E-2
|
3.312E-1
|
2
|
132
|
33
|
GO:1990239
|
steroid hormone binding
|
|
4.173E-3
|
1.105E-2
|
5.614E-2
|
3.756E-1
|
1
|
6
|
34
|
GO:0016530
|
metallochaperone activity
|
|
4.173E-3
|
1.105E-2
|
5.614E-2
|
3.756E-1
|
1
|
6
|
35
|
GO:0003988
|
acetyl-CoA C-acyltransferase activity
|
|
4.867E-3
|
1.252E-2
|
6.361E-2
|
4.380E-1
|
1
|
7
|
36
|
GO:0072509
|
divalent inorganic cation transmembrane transporter activity
|
|
6.232E-3
|
1.443E-2
|
7.335E-2
|
5.609E-1
|
2
|
173
|
37
|
GO:0103116
|
alpha-D-galactofuranose transporter activity
|
|
6.254E-3
|
1.443E-2
|
7.335E-2
|
5.628E-1
|
1
|
9
|
38
|
GO:0003857
|
3-hydroxyacyl-CoA dehydrogenase activity
|
|
6.254E-3
|
1.443E-2
|
7.335E-2
|
5.628E-1
|
1
|
9
|
39
|
GO:0030346
|
protein phosphatase 2B binding
|
|
6.254E-3
|
1.443E-2
|
7.335E-2
|
5.628E-1
|
1
|
9
|
40
|
GO:0008494
|
translation activator activity
|
|
6.946E-3
|
1.488E-2
|
7.565E-2
|
6.252E-1
|
1
|
10
|
41
|
GO:0005338
|
nucleotide-sugar transmembrane transporter activity
|
|
6.946E-3
|
1.488E-2
|
7.565E-2
|
6.252E-1
|
1
|
10
|
42
|
GO:0030235
|
nitric-oxide synthase regulator activity
|
|
6.946E-3
|
1.488E-2
|
7.565E-2
|
6.252E-1
|
1
|
10
|
43
|
GO:0005391
|
sodium:potassium-exchanging ATPase activity
|
|
7.638E-3
|
1.599E-2
|
8.126E-2
|
6.875E-1
|
1
|
11
|
44
|
GO:0098847
|
sequence-specific single stranded DNA binding
|
|
8.330E-3
|
1.666E-2
|
8.468E-2
|
7.497E-1
|
1
|
12
|
45
|
GO:0008556
|
potassium-transporting ATPase activity
|
|
8.330E-3
|
1.666E-2
|
8.468E-2
|
7.497E-1
|
1
|
12
|
46
|
GO:0030955
|
potassium ion binding
|
|
1.040E-2
|
2.035E-2
|
1.034E-1
|
9.362E-1
|
1
|
15
|
47
|
GO:0031402
|
sodium ion binding
|
|
1.109E-2
|
2.124E-2
|
1.080E-1
|
9.983E-1
|
1
|
16
|
48
|
GO:0015215
|
nucleotide transmembrane transporter activity
|
|
1.385E-2
|
2.596E-2
|
1.320E-1
|
1.000E0
|
1
|
20
|
49
|
GO:0030506
|
ankyrin binding
|
|
1.454E-2
|
2.670E-2
|
1.357E-1
|
1.000E0
|
1
|
21
|
50
|
GO:0050998
|
nitric-oxide synthase binding
|
|
1.522E-2
|
2.686E-2
|
1.365E-1
|
1.000E0
|
1
|
22
|
Show 45 more annotations
|
2: GO: Biological Process [Display Chart]
13 input genes in category / 589 annotations before applied cutoff / 18623 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
GO:0000041
|
transition metal ion transport
|
|
9.420E-11
|
5.549E-8
|
3.860E-7
|
5.549E-8
|
6
|
118
|
2
|
GO:0090383
|
phagosome acidification
|
|
2.895E-9
|
7.576E-7
|
5.270E-6
|
1.705E-6
|
4
|
28
|
3
|
GO:0015988
|
energy coupled proton transmembrane transport, against electrochemical gradient
|
|
5.775E-9
|
7.576E-7
|
5.270E-6
|
3.401E-6
|
4
|
33
|
4
|
GO:0015991
|
ATP hydrolysis coupled proton transport
|
|
5.775E-9
|
7.576E-7
|
5.270E-6
|
3.401E-6
|
4
|
33
|
5
|
GO:0030004
|
cellular monovalent inorganic cation homeostasis
|
|
6.742E-9
|
7.576E-7
|
5.270E-6
|
3.971E-6
|
5
|
106
|
6
|
GO:0033572
|
transferrin transport
|
|
8.303E-9
|
7.576E-7
|
5.270E-6
|
4.890E-6
|
4
|
36
|
7
|
GO:0090662
|
ATP hydrolysis coupled transmembrane transport
|
|
9.306E-9
|
7.576E-7
|
5.270E-6
|
5.481E-6
|
4
|
37
|
8
|
GO:0090382
|
phagosome maturation
|
|
1.158E-8
|
7.576E-7
|
5.270E-6
|
6.821E-6
|
4
|
39
|
9
|
GO:0072512
|
trivalent inorganic cation transport
|
|
1.286E-8
|
7.576E-7
|
5.270E-6
|
7.576E-6
|
4
|
40
|
10
|
GO:0015682
|
ferric iron transport
|
|
1.286E-8
|
7.576E-7
|
5.270E-6
|
7.576E-6
|
4
|
40
|
11
|
GO:0051452
|
intracellular pH reduction
|
|
2.730E-8
|
1.462E-6
|
1.017E-5
|
1.608E-5
|
4
|
48
|
12
|
GO:0045851
|
pH reduction
|
|
3.502E-8
|
1.719E-6
|
1.196E-5
|
2.063E-5
|
4
|
51
|
13
|
GO:0055067
|
monovalent inorganic cation homeostasis
|
|
5.026E-8
|
2.277E-6
|
1.584E-5
|
2.960E-5
|
5
|
158
|
14
|
GO:0006826
|
iron ion transport
|
|
7.285E-8
|
3.065E-6
|
2.132E-5
|
4.291E-5
|
4
|
61
|
15
|
GO:0051453
|
regulation of intracellular pH
|
|
2.083E-7
|
8.179E-6
|
5.690E-5
|
1.227E-4
|
4
|
79
|
16
|
GO:0030641
|
regulation of cellular pH
|
|
2.305E-7
|
8.484E-6
|
5.902E-5
|
1.357E-4
|
4
|
81
|
17
|
GO:0060003
|
copper ion export
|
|
4.498E-7
|
1.559E-5
|
1.084E-4
|
2.650E-4
|
2
|
2
|
18
|
GO:0006885
|
regulation of pH
|
|
5.839E-7
|
1.911E-5
|
1.329E-4
|
3.439E-4
|
4
|
102
|
19
|
GO:1902600
|
proton transmembrane transport
|
|
7.346E-7
|
2.277E-5
|
1.584E-4
|
4.327E-4
|
4
|
108
|
20
|
GO:0008286
|
insulin receptor signaling pathway
|
|
1.362E-6
|
4.012E-5
|
2.791E-4
|
8.025E-4
|
4
|
126
|
21
|
GO:0035434
|
copper ion transmembrane transport
|
|
6.737E-6
|
1.890E-4
|
1.314E-3
|
3.968E-3
|
2
|
6
|
22
|
GO:0043434
|
response to peptide hormone
|
|
8.097E-6
|
2.168E-4
|
1.508E-3
|
4.769E-3
|
5
|
442
|
23
|
GO:0032869
|
cellular response to insulin stimulus
|
|
9.989E-6
|
2.558E-4
|
1.780E-3
|
5.884E-3
|
4
|
208
|
24
|
GO:1901652
|
response to peptide
|
|
1.172E-5
|
2.877E-4
|
2.001E-3
|
6.904E-3
|
5
|
477
|
25
|
GO:1903779
|
regulation of cardiac conduction
|
|
1.241E-5
|
2.923E-4
|
2.033E-3
|
7.307E-3
|
3
|
67
|
26
|
GO:0015677
|
copper ion import
|
|
1.615E-5
|
3.523E-4
|
2.451E-3
|
9.512E-3
|
2
|
9
|
27
|
GO:0098739
|
import across plasma membrane
|
|
1.615E-5
|
3.523E-4
|
2.451E-3
|
9.512E-3
|
2
|
9
|
28
|
GO:0032868
|
response to insulin
|
|
2.629E-5
|
5.530E-4
|
3.847E-3
|
1.548E-2
|
4
|
266
|
29
|
GO:0006878
|
cellular copper ion homeostasis
|
|
5.368E-5
|
1.054E-3
|
7.332E-3
|
3.162E-2
|
2
|
16
|
30
|
GO:0045989
|
positive regulation of striated muscle contraction
|
|
5.368E-5
|
1.054E-3
|
7.332E-3
|
3.162E-2
|
2
|
16
|
31
|
GO:0071375
|
cellular response to peptide hormone stimulus
|
|
5.680E-5
|
1.079E-3
|
7.508E-3
|
3.346E-2
|
4
|
324
|
32
|
GO:0055070
|
copper ion homeostasis
|
|
6.839E-5
|
1.223E-3
|
8.507E-3
|
4.028E-2
|
2
|
18
|
33
|
GO:1901653
|
cellular response to peptide
|
|
6.851E-5
|
1.223E-3
|
8.507E-3
|
4.035E-2
|
4
|
340
|
34
|
GO:0061337
|
cardiac conduction
|
|
9.240E-5
|
1.578E-3
|
1.098E-2
|
5.442E-2
|
3
|
131
|
35
|
GO:0006825
|
copper ion transport
|
|
9.376E-5
|
1.578E-3
|
1.098E-2
|
5.522E-2
|
2
|
21
|
36
|
GO:0016241
|
regulation of macroautophagy
|
|
1.610E-4
|
2.634E-3
|
1.832E-2
|
9.483E-2
|
3
|
158
|
37
|
GO:0046688
|
response to copper ion
|
|
1.807E-4
|
2.877E-3
|
2.001E-2
|
1.064E-1
|
2
|
29
|
38
|
GO:0090075
|
relaxation of muscle
|
|
1.935E-4
|
3.000E-3
|
2.087E-2
|
1.140E-1
|
2
|
30
|
39
|
GO:0002026
|
regulation of the force of heart contraction
|
|
2.346E-4
|
3.543E-3
|
2.465E-2
|
1.382E-1
|
2
|
33
|
40
|
GO:0032104
|
regulation of response to extracellular stimulus
|
|
2.523E-4
|
3.624E-3
|
2.521E-2
|
1.486E-1
|
3
|
184
|
41
|
GO:0032107
|
regulation of response to nutrient levels
|
|
2.523E-4
|
3.624E-3
|
2.521E-2
|
1.486E-1
|
3
|
184
|
42
|
GO:0035637
|
multicellular organismal signaling
|
|
3.084E-4
|
4.324E-3
|
3.008E-2
|
1.816E-1
|
3
|
197
|
43
|
GO:0090257
|
regulation of muscle system process
|
|
4.205E-4
|
5.760E-3
|
4.007E-2
|
2.477E-1
|
3
|
219
|
44
|
GO:0007595
|
lactation
|
|
4.379E-4
|
5.861E-3
|
4.077E-2
|
2.579E-1
|
2
|
45
|
45
|
GO:0045933
|
positive regulation of muscle contraction
|
|
4.983E-4
|
6.522E-3
|
4.537E-2
|
2.935E-1
|
2
|
48
|
46
|
GO:0046034
|
ATP metabolic process
|
|
5.629E-4
|
7.054E-3
|
4.907E-2
|
3.316E-1
|
3
|
242
|
47
|
GO:0008016
|
regulation of heart contraction
|
|
5.629E-4
|
7.054E-3
|
4.907E-2
|
3.316E-1
|
3
|
242
|
48
|
GO:0098657
|
import into cell
|
|
6.307E-4
|
7.213E-3
|
5.018E-2
|
3.715E-1
|
2
|
54
|
49
|
GO:0033242
|
negative regulation of cellular amine catabolic process
|
|
6.981E-4
|
7.213E-3
|
5.018E-2
|
4.112E-1
|
1
|
1
|
50
|
GO:1903249
|
negative regulation of citrulline biosynthetic process
|
|
6.981E-4
|
7.213E-3
|
5.018E-2
|
4.112E-1
|
1
|
1
|
Show 45 more annotations
|
3: GO: Cellular Component [Display Chart]
13 input genes in category / 117 annotations before applied cutoff / 19061 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
GO:0033176
|
proton-transporting V-type ATPase complex
|
|
1.143E-9
|
1.338E-7
|
7.148E-7
|
1.338E-7
|
4
|
23
|
2
|
GO:0016469
|
proton-transporting two-sector ATPase complex
|
|
2.489E-8
|
1.456E-6
|
7.779E-6
|
2.912E-6
|
4
|
48
|
3
|
GO:0098852
|
lytic vacuole membrane
|
|
7.314E-7
|
2.139E-5
|
1.143E-4
|
8.558E-5
|
5
|
277
|
4
|
GO:0005765
|
lysosomal membrane
|
|
7.314E-7
|
2.139E-5
|
1.143E-4
|
8.558E-5
|
5
|
277
|
5
|
GO:0033180
|
proton-transporting V-type ATPase, V1 domain
|
|
1.542E-5
|
3.336E-4
|
1.783E-3
|
1.804E-3
|
2
|
9
|
6
|
GO:0016323
|
basolateral plasma membrane
|
|
1.711E-5
|
3.336E-4
|
1.783E-3
|
2.002E-3
|
4
|
244
|
7
|
GO:0033178
|
proton-transporting two-sector ATPase complex, catalytic domain
|
|
5.806E-5
|
9.705E-4
|
5.186E-3
|
6.793E-3
|
2
|
17
|
8
|
GO:0030140
|
trans-Golgi network transport vesicle
|
|
1.848E-4
|
2.702E-3
|
1.444E-2
|
2.162E-2
|
2
|
30
|
9
|
GO:0005802
|
trans-Golgi network
|
|
3.774E-4
|
4.907E-3
|
2.622E-2
|
4.416E-2
|
3
|
216
|
10
|
GO:0030315
|
T-tubule
|
|
7.433E-4
|
8.696E-3
|
4.647E-2
|
8.696E-2
|
2
|
60
|
11
|
GO:0031526
|
brush border membrane
|
|
8.718E-4
|
9.272E-3
|
4.955E-2
|
1.020E-1
|
2
|
65
|
12
|
GO:0098791
|
Golgi subcompartment
|
|
1.248E-3
|
9.778E-3
|
5.225E-2
|
1.460E-1
|
3
|
326
|
13
|
GO:0036125
|
fatty acid beta-oxidation multienzyme complex
|
|
1.364E-3
|
9.778E-3
|
5.225E-2
|
1.595E-1
|
1
|
2
|
14
|
GO:0031673
|
H zone
|
|
1.364E-3
|
9.778E-3
|
5.225E-2
|
1.595E-1
|
1
|
2
|
15
|
GO:0016507
|
mitochondrial fatty acid beta-oxidation multienzyme complex
|
|
1.364E-3
|
9.778E-3
|
5.225E-2
|
1.595E-1
|
1
|
2
|
16
|
GO:0032588
|
trans-Golgi network membrane
|
|
1.383E-3
|
9.778E-3
|
5.225E-2
|
1.618E-1
|
2
|
82
|
17
|
GO:0031984
|
organelle subcompartment
|
|
1.421E-3
|
9.778E-3
|
5.225E-2
|
1.662E-1
|
3
|
341
|
18
|
GO:0005798
|
Golgi-associated vesicle
|
|
1.520E-3
|
9.877E-3
|
5.278E-2
|
1.778E-1
|
2
|
86
|
19
|
GO:0005901
|
caveola
|
|
1.888E-3
|
1.163E-2
|
6.214E-2
|
2.210E-1
|
2
|
96
|
20
|
GO:0042470
|
melanosome
|
|
2.253E-3
|
1.198E-2
|
6.404E-2
|
2.636E-1
|
2
|
105
|
21
|
GO:0048770
|
pigment granule
|
|
2.253E-3
|
1.198E-2
|
6.404E-2
|
2.636E-1
|
2
|
105
|
22
|
GO:0044853
|
plasma membrane raft
|
|
2.253E-3
|
1.198E-2
|
6.404E-2
|
2.636E-1
|
2
|
105
|
23
|
GO:0045177
|
apical part of cell
|
|
2.719E-3
|
1.383E-2
|
7.391E-2
|
3.181E-1
|
3
|
428
|
24
|
GO:0005903
|
brush border
|
|
3.376E-3
|
1.646E-2
|
8.795E-2
|
3.950E-1
|
2
|
129
|
25
|
GO:0031674
|
I band
|
|
3.690E-3
|
1.727E-2
|
9.229E-2
|
4.318E-1
|
2
|
135
|
26
|
GO:0030121
|
AP-1 adaptor complex
|
|
4.086E-3
|
1.770E-2
|
9.461E-2
|
4.780E-1
|
1
|
6
|
27
|
GO:0000220
|
vacuolar proton-transporting V-type ATPase, V0 domain
|
|
4.086E-3
|
1.770E-2
|
9.461E-2
|
4.780E-1
|
1
|
6
|
28
|
GO:0042383
|
sarcolemma
|
|
4.652E-3
|
1.944E-2
|
1.039E-1
|
5.442E-1
|
2
|
152
|
29
|
GO:0030666
|
endocytic vesicle membrane
|
|
4.893E-3
|
1.974E-2
|
1.055E-1
|
5.725E-1
|
2
|
156
|
30
|
GO:0030136
|
clathrin-coated vesicle
|
|
5.266E-3
|
2.054E-2
|
1.097E-1
|
6.161E-1
|
2
|
162
|
31
|
GO:0098862
|
cluster of actin-based cell projections
|
|
6.117E-3
|
2.239E-2
|
1.196E-1
|
7.157E-1
|
2
|
175
|
32
|
GO:0031095
|
platelet dense tubular network membrane
|
|
6.123E-3
|
2.239E-2
|
1.196E-1
|
7.164E-1
|
1
|
9
|
33
|
GO:0033179
|
proton-transporting V-type ATPase, V0 domain
|
|
6.801E-3
|
2.411E-2
|
1.288E-1
|
7.957E-1
|
1
|
10
|
34
|
GO:0005890
|
sodium:potassium-exchanging ATPase complex
|
|
7.479E-3
|
2.500E-2
|
1.336E-1
|
8.750E-1
|
1
|
11
|
35
|
GO:0031094
|
platelet dense tubular network
|
|
7.479E-3
|
2.500E-2
|
1.336E-1
|
8.750E-1
|
1
|
11
|
36
|
GO:0030017
|
sarcomere
|
|
7.767E-3
|
2.511E-2
|
1.342E-1
|
9.087E-1
|
2
|
198
|
37
|
GO:0043209
|
myelin sheath
|
|
8.072E-3
|
2.511E-2
|
1.342E-1
|
9.444E-1
|
2
|
202
|
38
|
GO:0030130
|
clathrin coat of trans-Golgi network vesicle
|
|
8.156E-3
|
2.511E-2
|
1.342E-1
|
9.542E-1
|
1
|
12
|
39
|
GO:0044449
|
contractile fiber part
|
|
9.102E-3
|
2.715E-2
|
1.451E-1
|
1.000E0
|
2
|
215
|
40
|
GO:0016471
|
vacuolar proton-transporting V-type ATPase complex
|
|
9.509E-3
|
2.715E-2
|
1.451E-1
|
1.000E0
|
1
|
14
|
41
|
GO:0030016
|
myofibril
|
|
9.512E-3
|
2.715E-2
|
1.451E-1
|
1.000E0
|
2
|
220
|
42
|
GO:0005770
|
late endosome
|
|
9.847E-3
|
2.743E-2
|
1.466E-1
|
1.000E0
|
2
|
224
|
43
|
GO:0012510
|
trans-Golgi network transport vesicle membrane
|
|
1.019E-2
|
2.771E-2
|
1.481E-1
|
1.000E0
|
1
|
15
|
44
|
GO:0043292
|
contractile fiber
|
|
1.071E-2
|
2.824E-2
|
1.509E-1
|
1.000E0
|
2
|
234
|
45
|
GO:0090533
|
cation-transporting ATPase complex
|
|
1.086E-2
|
2.824E-2
|
1.509E-1
|
1.000E0
|
1
|
16
|
46
|
GO:0030135
|
coated vesicle
|
|
1.133E-2
|
2.881E-2
|
1.540E-1
|
1.000E0
|
2
|
241
|
47
|
GO:0030139
|
endocytic vesicle
|
|
1.358E-2
|
3.380E-2
|
1.806E-1
|
1.000E0
|
2
|
265
|
48
|
GO:0033177
|
proton-transporting two-sector ATPase complex, proton-transporting domain
|
|
1.558E-2
|
3.720E-2
|
1.988E-1
|
1.000E0
|
1
|
23
|
49
|
GO:0097228
|
sperm principal piece
|
|
1.558E-2
|
3.720E-2
|
1.988E-1
|
1.000E0
|
1
|
23
|
50
|
GO:0098533
|
ATPase dependent transmembrane transport complex
|
|
1.625E-2
|
3.803E-2
|
2.032E-1
|
1.000E0
|
1
|
24
|
Show 45 more annotations
|
4: Human Phenotype [Display Chart]
8 input genes in category / 878 annotations before applied cutoff / 4707 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
HP:0011967
|
Hypocupremia
|
|
1.514E-5
|
1.330E-2
|
9.779E-2
|
1.330E-2
|
2
|
4
|
2
|
HP:0010837
|
Decreased serum ceruloplasmin
|
|
5.286E-5
|
2.321E-2
|
1.707E-1
|
4.642E-2
|
2
|
7
|
3
|
HP:0010836
|
Abnormality of copper homeostasis
|
|
9.047E-5
|
2.648E-2
|
1.948E-1
|
7.943E-2
|
2
|
9
|
|
5: Mouse Phenotype [Display Chart]
12 input genes in category / 382 annotations before applied cutoff / 10355 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
MP:0010243
|
increased kidney copper level
|
|
1.231E-6
|
4.703E-4
|
3.068E-3
|
4.703E-4
|
2
|
2
|
2
|
MP:0010242
|
abnormal kidney copper level
|
|
3.691E-6
|
7.050E-4
|
4.599E-3
|
1.410E-3
|
2
|
3
|
3
|
MP:0006349
|
decreased circulating copper level
|
|
7.377E-6
|
7.823E-4
|
5.104E-3
|
2.818E-3
|
2
|
4
|
4
|
MP:0011213
|
abnormal brain copper level
|
|
1.229E-5
|
7.823E-4
|
5.104E-3
|
4.694E-3
|
2
|
5
|
5
|
MP:0006348
|
abnormal circulating copper level
|
|
1.229E-5
|
7.823E-4
|
5.104E-3
|
4.694E-3
|
2
|
5
|
6
|
MP:0003067
|
decreased liver copper level
|
|
1.229E-5
|
7.823E-4
|
5.104E-3
|
4.694E-3
|
2
|
5
|
7
|
MP:0003065
|
abnormal liver copper level
|
|
5.512E-5
|
3.008E-3
|
1.962E-2
|
2.105E-2
|
2
|
10
|
8
|
MP:0003952
|
abnormal copper level
|
|
8.074E-5
|
3.855E-3
|
2.515E-2
|
3.084E-2
|
2
|
12
|
9
|
MP:0003951
|
abnormal copper homeostasis
|
|
9.535E-5
|
4.047E-3
|
2.640E-2
|
3.642E-2
|
2
|
13
|
10
|
MP:0001274
|
curly vibrissae
|
|
3.940E-4
|
1.505E-2
|
9.819E-2
|
1.505E-1
|
2
|
26
|
11
|
MP:0000738
|
impaired muscle contractility
|
|
4.689E-4
|
1.628E-2
|
1.062E-1
|
1.791E-1
|
4
|
342
|
12
|
MP:0010247
|
increased intestine copper level
|
|
1.159E-3
|
3.405E-2
|
2.222E-1
|
4.427E-1
|
1
|
1
|
13
|
MP:0002845
|
abnormal aortic weight
|
|
1.159E-3
|
3.405E-2
|
2.222E-1
|
4.427E-1
|
1
|
1
|
14
|
MP:0005620
|
abnormal muscle contractility
|
|
1.275E-3
|
3.480E-2
|
2.270E-1
|
4.871E-1
|
4
|
446
|
15
|
MP:0006350
|
increased circulating copper level
|
|
2.316E-3
|
4.424E-2
|
2.887E-1
|
8.849E-1
|
1
|
2
|
16
|
MP:0010246
|
abnormal intestine copper level
|
|
2.316E-3
|
4.424E-2
|
2.887E-1
|
8.849E-1
|
1
|
2
|
17
|
MP:0011214
|
increased brain copper level
|
|
2.316E-3
|
4.424E-2
|
2.887E-1
|
8.849E-1
|
1
|
2
|
18
|
MP:0012661
|
decreased circulating ceruloplasmin level
|
|
2.316E-3
|
4.424E-2
|
2.887E-1
|
8.849E-1
|
1
|
2
|
19
|
MP:0011351
|
absent proximal convoluted tubule brush border
|
|
2.316E-3
|
4.424E-2
|
2.887E-1
|
8.849E-1
|
1
|
2
|
20
|
MP:0003907
|
decreased aorta elastin content
|
|
2.316E-3
|
4.424E-2
|
2.887E-1
|
8.849E-1
|
1
|
2
|
Show 15 more annotations
|
6: Domain [Display Chart]
13 input genes in category / 77 annotations before applied cutoff / 18735 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
IPR023299
|
ATPase P-typ cyto domN
|
InterPro
|
2.150E-11
|
3.703E-10
|
1.824E-9
|
1.656E-9
|
5
|
35
|
2
|
IPR001757
|
P typ ATPase
|
InterPro
|
2.496E-11
|
3.703E-10
|
1.824E-9
|
1.922E-9
|
5
|
36
|
3
|
PS00154
|
ATPASE E1 E2
|
PROSITE
|
2.496E-11
|
3.703E-10
|
1.824E-9
|
1.922E-9
|
5
|
36
|
4
|
IPR018303
|
ATPase P-typ P site
|
InterPro
|
2.496E-11
|
3.703E-10
|
1.824E-9
|
1.922E-9
|
5
|
36
|
5
|
PF00122
|
E1-E2 ATPase
|
Pfam
|
2.885E-11
|
3.703E-10
|
1.824E-9
|
2.222E-9
|
5
|
37
|
6
|
IPR008250
|
ATPase P-typ transduc dom A
|
InterPro
|
2.885E-11
|
3.703E-10
|
1.824E-9
|
2.222E-9
|
5
|
37
|
7
|
IPR023214
|
HAD-like dom
|
InterPro
|
1.470E-9
|
1.616E-8
|
7.965E-8
|
1.132E-7
|
5
|
79
|
8
|
3.40.1110.10
|
-
|
Gene3D
|
4.957E-9
|
4.241E-8
|
2.090E-7
|
3.817E-7
|
4
|
32
|
9
|
2.70.150.10
|
-
|
Gene3D
|
4.957E-9
|
4.241E-8
|
2.090E-7
|
3.817E-7
|
4
|
32
|
10
|
1.20.1110.10
|
-
|
Gene3D
|
1.454E-7
|
1.018E-6
|
5.015E-6
|
1.120E-5
|
3
|
16
|
11
|
IPR023298
|
ATPase P-typ TM dom
|
InterPro
|
1.454E-7
|
1.018E-6
|
5.015E-6
|
1.120E-5
|
3
|
16
|
12
|
IPR006068
|
ATPase P-typ cation-transptr C
|
InterPro
|
1.765E-7
|
1.045E-6
|
5.151E-6
|
1.359E-5
|
3
|
17
|
13
|
PF00689
|
Cation ATPase C
|
Pfam
|
1.765E-7
|
1.045E-6
|
5.151E-6
|
1.359E-5
|
3
|
17
|
14
|
SM00831
|
Cation ATPase N
|
SMART
|
2.117E-7
|
1.087E-6
|
5.355E-6
|
1.630E-5
|
3
|
18
|
15
|
PF00690
|
Cation ATPase N
|
Pfam
|
2.117E-7
|
1.087E-6
|
5.355E-6
|
1.630E-5
|
3
|
18
|
16
|
IPR004014
|
ATPase P-typ cation-transptr N
|
InterPro
|
2.513E-7
|
1.209E-6
|
5.959E-6
|
1.935E-5
|
3
|
19
|
17
|
IPR006122
|
HMA Cu ion-bd
|
InterPro
|
4.445E-7
|
1.901E-6
|
9.369E-6
|
3.422E-5
|
2
|
2
|
18
|
IPR027256
|
P-typ ATPase IB
|
InterPro
|
4.445E-7
|
1.901E-6
|
9.369E-6
|
3.422E-5
|
2
|
2
|
19
|
IPR017969
|
Heavy-metal-associated CS
|
InterPro
|
1.333E-6
|
5.402E-6
|
2.662E-5
|
1.026E-4
|
2
|
3
|
20
|
PF00403
|
HMA
|
Pfam
|
2.665E-6
|
9.327E-6
|
4.596E-5
|
2.052E-4
|
2
|
4
|
21
|
PS50846
|
HMA 2
|
PROSITE
|
2.665E-6
|
9.327E-6
|
4.596E-5
|
2.052E-4
|
2
|
4
|
22
|
PS01047
|
HMA 1
|
PROSITE
|
2.665E-6
|
9.327E-6
|
4.596E-5
|
2.052E-4
|
2
|
4
|
23
|
IPR006121
|
HMA dom
|
InterPro
|
9.316E-6
|
3.119E-5
|
1.537E-4
|
7.173E-4
|
2
|
7
|
24
|
PF07850
|
Renin r
|
Pfam
|
6.939E-4
|
1.908E-3
|
9.403E-3
|
5.343E-2
|
1
|
1
|
25
|
PF01813
|
ATP-synt D
|
Pfam
|
6.939E-4
|
1.908E-3
|
9.403E-3
|
5.343E-2
|
1
|
1
|
26
|
IPR012493
|
Renin rcpt
|
InterPro
|
6.939E-4
|
1.908E-3
|
9.403E-3
|
5.343E-2
|
1
|
1
|
27
|
IPR030332
|
SERCA1
|
InterPro
|
6.939E-4
|
1.908E-3
|
9.403E-3
|
5.343E-2
|
1
|
1
|
28
|
IPR002699
|
V ATPase D
|
InterPro
|
6.939E-4
|
1.908E-3
|
9.403E-3
|
5.343E-2
|
1
|
1
|
29
|
3.40.50.1000
|
-
|
Gene3D
|
8.746E-4
|
2.322E-3
|
1.144E-2
|
6.734E-2
|
2
|
64
|
30
|
IPR030319
|
ATP2B1/4
|
InterPro
|
1.387E-3
|
3.142E-3
|
1.548E-2
|
1.068E-1
|
1
|
2
|
31
|
IPR005723
|
ATPase V1-cplx bsu
|
InterPro
|
1.387E-3
|
3.142E-3
|
1.548E-2
|
1.068E-1
|
1
|
2
|
32
|
IPR022879
|
V-ATPase su B/beta
|
InterPro
|
1.387E-3
|
3.142E-3
|
1.548E-2
|
1.068E-1
|
1
|
2
|
33
|
PF03223
|
V-ATPase C
|
Pfam
|
1.387E-3
|
3.142E-3
|
1.548E-2
|
1.068E-1
|
1
|
2
|
34
|
IPR004907
|
ATPase V1-cplx csu
|
InterPro
|
1.387E-3
|
3.142E-3
|
1.548E-2
|
1.068E-1
|
1
|
2
|
35
|
IPR005782
|
P-type ATPase IIA
|
InterPro
|
2.080E-3
|
4.577E-3
|
2.255E-2
|
1.602E-1
|
1
|
3
|
36
|
IPR006408
|
P-type ATPase IIB
|
InterPro
|
2.773E-3
|
5.208E-3
|
2.566E-2
|
2.135E-1
|
1
|
4
|
37
|
IPR002490
|
V-ATPase 116kDa su
|
InterPro
|
2.773E-3
|
5.208E-3
|
2.566E-2
|
2.135E-1
|
1
|
4
|
38
|
IPR022141
|
ATP Ca trans C
|
InterPro
|
2.773E-3
|
5.208E-3
|
2.566E-2
|
2.135E-1
|
1
|
4
|
39
|
PF01496
|
V ATPase I
|
Pfam
|
2.773E-3
|
5.208E-3
|
2.566E-2
|
2.135E-1
|
1
|
4
|
40
|
PF12424
|
ATP Ca trans C
|
Pfam
|
2.773E-3
|
5.208E-3
|
2.566E-2
|
2.135E-1
|
1
|
4
|
41
|
IPR026028
|
V-type ATPase 116kDa su euka
|
InterPro
|
2.773E-3
|
5.208E-3
|
2.566E-2
|
2.135E-1
|
1
|
4
|
42
|
IPR020615
|
Thiolase acyl enz int AS
|
InterPro
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
43
|
IPR020610
|
Thiolase AS
|
InterPro
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
44
|
PS00152
|
ATPASE ALPHA BETA
|
PROSITE
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
45
|
IPR000793
|
ATP synth asu C
|
InterPro
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
46
|
IPR020003
|
ATPase a/bsu AS
|
InterPro
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
47
|
IPR004100
|
ATPase F1/V1/A1 a/bsu N
|
InterPro
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
48
|
PF02874
|
ATP-synt ab N
|
Pfam
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
49
|
PF00006
|
ATP-synt ab
|
Pfam
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
50
|
PF00306
|
ATP-synt ab C
|
Pfam
|
3.465E-3
|
5.247E-3
|
2.585E-2
|
2.668E-1
|
1
|
5
|
Show 45 more annotations
|
7: Pathway [Display Chart]
13 input genes in category / 164 annotations before applied cutoff / 12450 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
1269950
|
Ion channel transport
|
BioSystems: REACTOME
|
6.014E-14
|
9.864E-12
|
5.603E-11
|
9.864E-12
|
9
|
209
|
2
|
MAP00190 Oxidative phosphorylation
|
MAP00190 Oxidative phosphorylation
|
GenMAPP
|
2.302E-12
|
1.888E-10
|
1.072E-9
|
3.776E-10
|
6
|
44
|
3
|
1269951
|
Ion transport by P-type ATPases
|
BioSystems: REACTOME
|
2.301E-9
|
9.006E-8
|
5.116E-7
|
3.774E-7
|
5
|
58
|
4
|
MAP03070 Type III secretion system
|
MAP03070 Type III secretion system
|
GenMAPP
|
2.746E-9
|
9.006E-8
|
5.116E-7
|
4.503E-7
|
4
|
19
|
5
|
MAP00193 ATP synthesis
|
MAP00193 ATP synthesis
|
GenMAPP
|
2.746E-9
|
9.006E-8
|
5.116E-7
|
4.503E-7
|
4
|
19
|
6
|
MAP00195 Photosynthesis
|
MAP00195 Photosynthesis
|
GenMAPP
|
3.430E-9
|
9.376E-8
|
5.326E-7
|
5.626E-7
|
4
|
20
|
7
|
1269442
|
Insulin receptor recycling
|
BioSystems: REACTOME
|
1.237E-8
|
2.537E-7
|
1.441E-6
|
2.029E-6
|
4
|
27
|
8
|
147586
|
Collecting duct acid secretion
|
BioSystems: KEGG
|
1.237E-8
|
2.537E-7
|
1.441E-6
|
2.029E-6
|
4
|
27
|
9
|
1269949
|
Transferrin endocytosis and recycling
|
BioSystems: REACTOME
|
1.929E-8
|
3.515E-7
|
1.997E-6
|
3.164E-6
|
4
|
30
|
10
|
1269138
|
ROS, RNS production in phagocytes
|
BioSystems: REACTOME
|
2.875E-8
|
4.716E-7
|
2.679E-6
|
4.716E-6
|
4
|
33
|
11
|
1269948
|
Iron uptake and transport
|
BioSystems: REACTOME
|
9.478E-8
|
1.413E-6
|
8.027E-6
|
1.554E-5
|
4
|
44
|
12
|
83101
|
Vibrio cholerae infection
|
BioSystems: KEGG
|
1.738E-7
|
2.375E-6
|
1.349E-5
|
2.850E-5
|
4
|
51
|
13
|
373900
|
Synaptic vesicle cycle
|
BioSystems: KEGG
|
4.113E-7
|
5.189E-6
|
2.948E-5
|
6.746E-5
|
4
|
63
|
14
|
83102
|
Epithelial cell signaling in Helicobacter pylori infection
|
BioSystems: KEGG
|
5.608E-7
|
6.569E-6
|
3.731E-5
|
9.196E-5
|
4
|
68
|
15
|
200309
|
Rheumatoid arthritis
|
BioSystems: KEGG
|
1.737E-6
|
1.899E-5
|
1.079E-4
|
2.849E-4
|
4
|
90
|
16
|
82942
|
Oxidative phosphorylation
|
BioSystems: KEGG
|
8.260E-6
|
8.466E-5
|
4.809E-4
|
1.355E-3
|
4
|
133
|
17
|
153910
|
Phagosome
|
BioSystems: KEGG
|
1.476E-5
|
1.424E-4
|
8.087E-4
|
2.420E-3
|
4
|
154
|
18
|
1339121
|
Ion homeostasis
|
BioSystems: REACTOME
|
2.388E-5
|
2.176E-4
|
1.236E-3
|
3.916E-3
|
3
|
56
|
19
|
PW:0000035
|
ATP synthetic
|
Pathway Ontology
|
6.604E-5
|
5.700E-4
|
3.238E-3
|
1.083E-2
|
2
|
12
|
20
|
1269347
|
Reduction of cytosolic Ca++ levels
|
BioSystems: REACTOME
|
9.095E-5
|
7.458E-4
|
4.236E-3
|
1.492E-2
|
2
|
14
|
21
|
169306
|
Pancreatic secretion
|
BioSystems: KEGG
|
1.201E-4
|
9.383E-4
|
5.330E-3
|
1.970E-2
|
3
|
96
|
22
|
1269428
|
Signaling by Insulin receptor
|
BioSystems: REACTOME
|
2.737E-4
|
2.040E-3
|
1.159E-2
|
4.488E-2
|
4
|
326
|
23
|
1339115
|
Cardiac conduction
|
BioSystems: REACTOME
|
3.821E-4
|
2.724E-3
|
1.547E-2
|
6.266E-2
|
3
|
142
|
24
|
83059
|
mTOR signaling pathway
|
BioSystems: KEGG
|
4.575E-4
|
3.018E-3
|
1.714E-2
|
7.503E-2
|
3
|
151
|
25
|
1269345
|
Platelet calcium homeostasis
|
BioSystems: REACTOME
|
4.601E-4
|
3.018E-3
|
1.714E-2
|
7.546E-2
|
2
|
31
|
26
|
983748
|
cGMP-PKG signaling pathway
|
BioSystems: KEGG
|
5.722E-4
|
3.609E-3
|
2.050E-2
|
9.384E-2
|
3
|
163
|
27
|
1269868
|
Muscle contraction
|
BioSystems: REACTOME
|
1.098E-3
|
6.671E-3
|
3.789E-2
|
1.801E-1
|
3
|
204
|
28
|
212237
|
Mineral absorption
|
BioSystems: KEGG
|
1.247E-3
|
7.303E-3
|
4.148E-2
|
2.045E-1
|
2
|
51
|
29
|
1404797
|
Platinum drug resistance
|
BioSystems: KEGG
|
2.537E-3
|
1.435E-2
|
8.149E-2
|
4.160E-1
|
2
|
73
|
30
|
1270017
|
Beta oxidation of palmitoyl-CoA to myristoyl-CoA
|
BioSystems: REACTOME
|
3.130E-3
|
1.656E-2
|
9.404E-2
|
5.132E-1
|
1
|
3
|
31
|
1270018
|
Beta oxidation of myristoyl-CoA to lauroyl-CoA
|
BioSystems: REACTOME
|
3.130E-3
|
1.656E-2
|
9.404E-2
|
5.132E-1
|
1
|
3
|
32
|
153376
|
Salivary secretion
|
BioSystems: KEGG
|
3.828E-3
|
1.944E-2
|
1.104E-1
|
6.277E-1
|
2
|
90
|
33
|
1269341
|
Platelet homeostasis
|
BioSystems: REACTOME
|
3.911E-3
|
1.944E-2
|
1.104E-1
|
6.414E-1
|
2
|
91
|
34
|
1457779
|
Ion influx/efflux at host-pathogen interface
|
BioSystems: REACTOME
|
4.171E-3
|
2.012E-2
|
1.143E-1
|
6.840E-1
|
1
|
4
|
35
|
1270022
|
Beta oxidation of hexanoyl-CoA to butanoyl-CoA
|
BioSystems: REACTOME
|
5.211E-3
|
2.249E-2
|
1.277E-1
|
8.546E-1
|
1
|
5
|
36
|
1270019
|
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
|
BioSystems: REACTOME
|
5.211E-3
|
2.249E-2
|
1.277E-1
|
8.546E-1
|
1
|
5
|
37
|
1270021
|
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
|
BioSystems: REACTOME
|
5.211E-3
|
2.249E-2
|
1.277E-1
|
8.546E-1
|
1
|
5
|
38
|
1270020
|
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
|
BioSystems: REACTOME
|
5.211E-3
|
2.249E-2
|
1.277E-1
|
8.546E-1
|
1
|
5
|
39
|
1270071
|
Acyl chain remodeling of CL
|
BioSystems: REACTOME
|
6.250E-3
|
2.500E-2
|
1.420E-1
|
1.000E0
|
1
|
6
|
40
|
1270024
|
mitochondrial fatty acid beta-oxidation of unsaturated fatty acids
|
BioSystems: REACTOME
|
6.250E-3
|
2.500E-2
|
1.420E-1
|
1.000E0
|
1
|
6
|
41
|
413380
|
Fatty acid biosynthesis, elongation, mitochondria
|
BioSystems: KEGG
|
6.250E-3
|
2.500E-2
|
1.420E-1
|
1.000E0
|
1
|
6
|
42
|
99052
|
Lysosome
|
BioSystems: KEGG
|
7.033E-3
|
2.533E-2
|
1.439E-1
|
1.000E0
|
2
|
123
|
43
|
SMP00054
|
Fatty Acid Elongation In Mitochondria
|
SMPDB
|
7.288E-3
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
7
|
44
|
MAP00062 Fatty acid biosynthesis path 2
|
MAP00062 Fatty acid biosynthesis path 2
|
GenMAPP
|
7.288E-3
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
7
|
45
|
SMP00186
|
Glutaric Aciduria Type III
|
SMPDB
|
9.361E-3
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
9
|
46
|
SMP00037
|
Lysine Degradation
|
SMPDB
|
9.361E-3
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
9
|
47
|
908257
|
Adrenergic signaling in cardiomyocytes
|
BioSystems: KEGG
|
9.532E-3
|
2.533E-2
|
1.439E-1
|
1.000E0
|
2
|
144
|
48
|
SMP00397
|
Levobupivacaine Pathway
|
SMPDB
|
1.040E-2
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
10
|
49
|
SMP00402
|
Procaine Pathway
|
SMPDB
|
1.040E-2
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
10
|
50
|
SMP00394
|
Chloroprocaine Pathway
|
SMPDB
|
1.040E-2
|
2.533E-2
|
1.439E-1
|
1.000E0
|
1
|
10
|
Show 45 more annotations
|
8: Pubmed [Display Chart]
13 input genes in category / 1635 annotations before applied cutoff / 38193 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
15071553
|
Biology, structure and mechanism of P-type ATPases.
|
Pubmed
|
2.248E-13
|
3.675E-10
|
2.932E-9
|
3.675E-10
|
5
|
29
|
2
|
10221984
|
Vacuolar and plasma membrane proton-adenosinetriphosphatases.
|
Pubmed
|
2.462E-11
|
6.371E-9
|
5.082E-8
|
4.025E-8
|
4
|
18
|
3
|
10440860
|
Animal plasma membrane energization by proton-motive V-ATPases.
|
Pubmed
|
2.462E-11
|
6.371E-9
|
5.082E-8
|
4.025E-8
|
4
|
18
|
4
|
9210392
|
The vacuolar H+-ATPase: a universal proton pump of eukaryotes.
|
Pubmed
|
2.462E-11
|
6.371E-9
|
5.082E-8
|
4.025E-8
|
4
|
18
|
5
|
10224039
|
Structure and properties of the vacuolar (H+)-ATPases.
|
Pubmed
|
2.462E-11
|
6.371E-9
|
5.082E-8
|
4.025E-8
|
4
|
18
|
6
|
10340843
|
Introduction: V-ATPases 1992-1998.
|
Pubmed
|
2.462E-11
|
6.371E-9
|
5.082E-8
|
4.025E-8
|
4
|
18
|
7
|
16177003
|
Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.
|
Pubmed
|
3.117E-11
|
6.371E-9
|
5.082E-8
|
5.097E-8
|
4
|
19
|
8
|
9442887
|
Structure, function and regulation of the vacuolar (H+)-ATPase.
|
Pubmed
|
3.117E-11
|
6.371E-9
|
5.082E-8
|
5.097E-8
|
4
|
19
|
9
|
14597263
|
Neurotransmitter release: the dark side of the vacuolar-H+ATPase.
|
Pubmed
|
5.880E-11
|
7.395E-9
|
5.899E-8
|
9.614E-8
|
4
|
22
|
10
|
14580332
|
Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genes.
|
Pubmed
|
5.880E-11
|
7.395E-9
|
5.899E-8
|
9.614E-8
|
4
|
22
|
11
|
17662945
|
Coupling of rotation and catalysis in F(1)-ATPase revealed by single-molecule imaging and manipulation.
|
Pubmed
|
5.880E-11
|
7.395E-9
|
5.899E-8
|
9.614E-8
|
4
|
22
|
12
|
12788495
|
Proton translocation driven by ATP hydrolysis in V-ATPases.
|
Pubmed
|
5.880E-11
|
7.395E-9
|
5.899E-8
|
9.614E-8
|
4
|
22
|
13
|
11836511
|
The vacuolar (H+)-ATPases--nature's most versatile proton pumps.
|
Pubmed
|
5.880E-11
|
7.395E-9
|
5.899E-8
|
9.614E-8
|
4
|
22
|
14
|
2874839
|
Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.
|
Pubmed
|
1.016E-10
|
1.187E-8
|
9.468E-8
|
1.662E-7
|
4
|
25
|
15
|
22982048
|
Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts.
|
Pubmed
|
3.500E-8
|
3.815E-6
|
3.043E-5
|
5.722E-5
|
3
|
20
|
16
|
17897319
|
Integral and associated lysosomal membrane proteins.
|
Pubmed
|
7.889E-8
|
4.265E-6
|
3.402E-5
|
1.290E-4
|
4
|
126
|
17
|
12539960
|
Copper transporting P-type ATPases and human disease.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
18
|
9823011
|
Genes regulating copper metabolism.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
19
|
27896900
|
Molecular features of copper binding proteins involved in copper homeostasis.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
20
|
21117320
|
[Structure and function of ATP7A and ATP7B proteins--Cu-transporting ATPases].
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
21
|
19645496
|
Solution structures of the actuator domain of ATP7A and ATP7B, the Menkes and Wilson disease proteins.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
22
|
8732640
|
Menkes disease: recent advances and new insights into copper metabolism.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
23
|
28820536
|
Atp7a and Atp7b regulate copper homeostasis in developing male germ cells in mice.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
24
|
8082762
|
Expression of the Menkes gene homologue in mouse tissues lack of effect of copper on the mRNA levels.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
25
|
15135234
|
Expression and localization of menkes and Wilson copper transporting ATPases in human placenta.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
26
|
18000748
|
Copper-transporting ATPases ATP7A and ATP7B: cousins, not twins.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
27
|
17531189
|
Trafficking of the copper-ATPases, ATP7A and ATP7B: role in copper homeostasis.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
28
|
12372948
|
Expression in mouse kidney of membrane copper transporters Atp7a and Atp7b.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
29
|
17109627
|
Hormonal regulation of the Menkes and Wilson copper-transporting ATPases in human placental Jeg-3 cells.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
30
|
17717039
|
Molecular pathogenesis of Wilson and Menkes disease: correlation of mutations with molecular defects and disease phenotypes.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
31
|
28271598
|
Dynamics of the metal binding domains and regulation of the human copper transporters ATP7B and ATP7A.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
32
|
17562324
|
Biochemical basis of regulation of human copper-transporting ATPases.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
33
|
28164426
|
Mechanisms of charge transfer in human copper ATPases ATP7A and ATP7B.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
34
|
18565219
|
Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
35
|
21115196
|
Differential intracellular localisation of the Menkes and Wilson copper transporting ATPases in the third trimester human placenta.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
36
|
20045993
|
Genetic polymorphisms of copper- and platinum drug-efflux transporters ATP7A and ATP7B in Japanese cancer patients.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
37
|
9392450
|
Regional brain distribution of metallothionein, zinc and copper in toxic milk mutant and transgenic mice.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
38
|
9215673
|
Developmental expression of the mouse mottled and toxic milk genes suggests distinct functions for the Menkes and Wilson disease copper transporters.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
39
|
17928409
|
Intracellular targeting of copper-transporting ATPase ATP7A in a normal and Atp7b-/- kidney.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
40
|
19046832
|
[From gene to disease: copper-transporting P ATPases alteration].
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
41
|
18688737
|
Quantitative relationship between mutated amino-acid sequence of human copper-transporting ATPases and their related diseases.
|
Pubmed
|
1.069E-7
|
4.265E-6
|
3.402E-5
|
1.749E-4
|
2
|
2
|
42
|
19199708
|
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
|
Pubmed
|
1.793E-7
|
6.978E-6
|
5.567E-5
|
2.931E-4
|
5
|
416
|
43
|
23798571
|
Novel, gel-free proteomics approach identifies RNF5 and JAMP as modulators of GPCR stability.
|
Pubmed
|
2.059E-7
|
7.830E-6
|
6.246E-5
|
3.367E-4
|
4
|
160
|
44
|
10557326
|
Interaction of the copper chaperone HAH1 with the Wilson disease protein is essential for copper homeostasis.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
45
|
23963605
|
Intestinal expression of metal transporters in Wilson's disease.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
46
|
28737129
|
Association between polymorphisms in CTR1, CTR2, ATP7A, and ATP7B and platinum resistance in epithelial ovarian cancer.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
47
|
15634671
|
The copper-transporting ATPases, menkes and wilson disease proteins, have distinct roles in adult and developing cerebellum.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
48
|
21242307
|
Clusterin (apolipoprotein J), a molecular chaperone that facilitates degradation of the copper-ATPases ATP7A and ATP7B.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
49
|
23751120
|
Copper chaperone Atox1 interacts with the metal-binding domain of Wilson's disease protein in cisplatin detoxification.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
50
|
10497213
|
Characterization of the interaction between the Wilson and Menkes disease proteins and the cytoplasmic copper chaperone, HAH1p.
|
Pubmed
|
3.208E-7
|
9.896E-6
|
7.894E-5
|
5.245E-4
|
2
|
3
|
Show 45 more annotations
|
9: Interaction [Display Chart]
13 input genes in category / 920 annotations before applied cutoff / 17703 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
int:TLDC2
|
TLDC2 interactions
|
|
1.081E-8
|
9.944E-6
|
7.361E-5
|
9.944E-6
|
3
|
7
|
2
|
int:ATP6V0A2
|
ATP6V0A2 interactions
|
|
7.254E-8
|
3.337E-5
|
2.470E-4
|
6.674E-5
|
4
|
58
|
3
|
int:ATP6V1E1
|
ATP6V1E1 interactions
|
|
1.154E-7
|
3.540E-5
|
2.620E-4
|
1.062E-4
|
4
|
65
|
4
|
int:ATP6V1B1
|
ATP6V1B1 interactions
|
|
6.076E-7
|
1.081E-4
|
8.001E-4
|
5.590E-4
|
4
|
98
|
5
|
int:ATP6V1A
|
ATP6V1A interactions
|
|
6.859E-7
|
1.081E-4
|
8.001E-4
|
6.311E-4
|
4
|
101
|
6
|
int:ATP6V1C2
|
ATP6V1C2 interactions
|
|
7.049E-7
|
1.081E-4
|
8.001E-4
|
6.485E-4
|
3
|
25
|
7
|
int:ATP6AP2
|
ATP6AP2 interactions
|
|
1.002E-6
|
1.317E-4
|
9.749E-4
|
9.219E-4
|
4
|
111
|
8
|
int:ATP6V0D1
|
ATP6V0D1 interactions
|
|
1.196E-6
|
1.375E-4
|
1.018E-3
|
1.100E-3
|
4
|
116
|
9
|
int:ATP6V1D
|
ATP6V1D interactions
|
|
6.312E-6
|
6.453E-4
|
4.776E-3
|
5.807E-3
|
3
|
51
|
10
|
int:ATP6V1F
|
ATP6V1F interactions
|
|
8.385E-6
|
7.714E-4
|
5.710E-3
|
7.714E-3
|
3
|
56
|
11
|
int:ADRB2
|
ADRB2 interactions
|
|
2.929E-5
|
2.449E-3
|
1.813E-2
|
2.694E-2
|
4
|
260
|
12
|
int:UBE2L6
|
UBE2L6 interactions
|
|
4.519E-5
|
3.465E-3
|
2.565E-2
|
4.158E-2
|
3
|
98
|
13
|
int:ATP6V1B2
|
ATP6V1B2 interactions
|
|
5.397E-5
|
3.820E-3
|
2.827E-2
|
4.965E-2
|
3
|
104
|
14
|
int:ATOX1
|
ATOX1 interactions
|
|
5.939E-5
|
3.903E-3
|
2.889E-2
|
5.464E-2
|
2
|
16
|
15
|
int:ITM2A
|
ITM2A interactions
|
|
6.728E-5
|
4.127E-3
|
3.055E-2
|
6.190E-2
|
2
|
17
|
16
|
int:FXYD1
|
FXYD1 interactions
|
|
9.388E-5
|
5.301E-3
|
3.924E-2
|
8.637E-2
|
2
|
20
|
17
|
int:ATP6V0D2
|
ATP6V0D2 interactions
|
|
1.037E-4
|
5.301E-3
|
3.924E-2
|
9.542E-2
|
2
|
21
|
18
|
int:PDZD11
|
PDZD11 interactions
|
|
1.037E-4
|
5.301E-3
|
3.924E-2
|
9.542E-2
|
2
|
21
|
19
|
int:TCIRG1
|
TCIRG1 interactions
|
|
1.140E-4
|
5.522E-3
|
4.088E-2
|
1.049E-1
|
2
|
22
|
20
|
int:GLRX
|
GLRX interactions
|
|
1.361E-4
|
6.263E-3
|
4.636E-2
|
1.253E-1
|
2
|
24
|
21
|
int:TMEM17
|
TMEM17 interactions
|
|
1.577E-4
|
6.699E-3
|
4.958E-2
|
1.451E-1
|
4
|
401
|
22
|
int:GPC1
|
GPC1 interactions
|
|
1.602E-4
|
6.699E-3
|
4.958E-2
|
1.474E-1
|
2
|
26
|
23
|
int:LAMTOR2
|
LAMTOR2 interactions
|
|
1.729E-4
|
6.917E-3
|
5.120E-2
|
1.591E-1
|
2
|
27
|
24
|
int:ATP1A1
|
ATP1A1 interactions
|
|
2.483E-4
|
9.517E-3
|
7.044E-2
|
2.284E-1
|
3
|
174
|
25
|
int:GOLT1B
|
GOLT1B interactions
|
|
3.117E-4
|
1.147E-2
|
8.490E-2
|
2.867E-1
|
3
|
188
|
26
|
int:ATP6V1G1
|
ATP6V1G1 interactions
|
|
3.633E-4
|
1.285E-2
|
9.515E-2
|
3.342E-1
|
2
|
39
|
27
|
int:DNAJB2
|
DNAJB2 interactions
|
|
5.059E-4
|
1.724E-2
|
1.276E-1
|
4.654E-1
|
2
|
46
|
28
|
int:ATF2
|
ATF2 interactions
|
|
5.411E-4
|
1.778E-2
|
1.316E-1
|
4.978E-1
|
3
|
227
|
29
|
int:CIAPIN1
|
CIAPIN1 interactions
|
|
5.978E-4
|
1.833E-2
|
1.357E-1
|
5.500E-1
|
2
|
50
|
30
|
int:ATP6AP1
|
ATP6AP1 interactions
|
|
5.978E-4
|
1.833E-2
|
1.357E-1
|
5.500E-1
|
2
|
50
|
31
|
int:CPT1A
|
CPT1A interactions
|
|
6.219E-4
|
1.846E-2
|
1.366E-1
|
5.722E-1
|
2
|
51
|
32
|
int:LAMTOR5
|
LAMTOR5 interactions
|
|
6.716E-4
|
1.931E-2
|
1.429E-1
|
6.179E-1
|
2
|
53
|
33
|
int:ATP6V1H
|
ATP6V1H interactions
|
|
7.232E-4
|
2.016E-2
|
1.492E-1
|
6.653E-1
|
2
|
55
|
34
|
int:ATP2B4
|
ATP2B4 interactions
|
|
8.890E-4
|
2.405E-2
|
1.781E-1
|
8.179E-1
|
2
|
61
|
35
|
int:RAB14
|
RAB14 interactions
|
|
9.182E-4
|
2.414E-2
|
1.787E-1
|
8.448E-1
|
2
|
62
|
36
|
int:ATP6V1C1
|
ATP6V1C1 interactions
|
|
9.479E-4
|
2.423E-2
|
1.793E-1
|
8.721E-1
|
2
|
63
|
37
|
int:SEC31A
|
SEC31A interactions
|
|
1.040E-3
|
2.586E-2
|
1.914E-1
|
9.567E-1
|
2
|
66
|
38
|
int:UBAC2
|
UBAC2 interactions
|
|
1.136E-3
|
2.707E-2
|
2.004E-1
|
1.000E0
|
2
|
69
|
39
|
int:UNK
|
UNK interactions
|
|
1.192E-3
|
2.707E-2
|
2.004E-1
|
1.000E0
|
3
|
298
|
40
|
int:MRPL40
|
MRPL40 interactions
|
|
1.202E-3
|
2.707E-2
|
2.004E-1
|
1.000E0
|
2
|
71
|
41
|
int:PCDHGB1
|
PCDHGB1 interactions
|
|
1.236E-3
|
2.707E-2
|
2.004E-1
|
1.000E0
|
2
|
72
|
42
|
int:PFKM
|
PFKM interactions
|
|
1.236E-3
|
2.707E-2
|
2.004E-1
|
1.000E0
|
2
|
72
|
43
|
int:ATP6V0A1
|
ATP6V0A1 interactions
|
|
1.305E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
2
|
74
|
44
|
int:COMMD1
|
COMMD1 interactions
|
|
1.340E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
2
|
75
|
45
|
int:CLEC2D
|
CLEC2D interactions
|
|
1.376E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
2
|
76
|
46
|
int:IQCB1
|
IQCB1 interactions
|
|
1.437E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
3
|
318
|
47
|
int:NUDT11
|
NUDT11 interactions
|
|
1.468E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
1
|
2
|
48
|
int:FXYD2
|
FXYD2 interactions
|
|
1.468E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
1
|
2
|
49
|
int:LGALS9
|
LGALS9 interactions
|
|
1.486E-3
|
2.789E-2
|
2.065E-1
|
1.000E0
|
2
|
79
|
50
|
int:COG6
|
COG6 interactions
|
|
1.523E-3
|
2.802E-2
|
2.074E-1
|
1.000E0
|
2
|
80
|
Show 45 more annotations
|
10: Cytoband [Display Chart]
13 input genes in category / 13 annotations before applied cutoff / 34661 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
14q23-q24.2
|
14q23-q24.2
|
|
1.125E-3
|
9.747E-3
|
3.100E-2
|
1.462E-2
|
1
|
3
|
2
|
2p13-p12
|
2p13-p12
|
|
1.499E-3
|
9.747E-3
|
3.100E-2
|
1.949E-2
|
1
|
4
|
3
|
2p23
|
2p23
|
|
6.358E-3
|
1.985E-2
|
6.313E-2
|
8.266E-2
|
1
|
17
|
4
|
16p12.1
|
16p12.1
|
|
9.338E-3
|
1.985E-2
|
6.313E-2
|
1.214E-1
|
1
|
25
|
5
|
1p21
|
1p21
|
|
9.338E-3
|
1.985E-2
|
6.313E-2
|
1.214E-1
|
1
|
25
|
6
|
Xq21.1
|
Xq21.1
|
|
1.305E-2
|
1.985E-2
|
6.313E-2
|
1.697E-1
|
1
|
35
|
7
|
Xp11.4
|
Xp11.4
|
|
1.379E-2
|
1.985E-2
|
6.313E-2
|
1.793E-1
|
1
|
37
|
8
|
8p21.3
|
8p21.3
|
|
1.453E-2
|
1.985E-2
|
6.313E-2
|
1.889E-1
|
1
|
39
|
9
|
8q22.3
|
8q22.3
|
|
1.453E-2
|
1.985E-2
|
6.313E-2
|
1.889E-1
|
1
|
39
|
10
|
13q14.3
|
13q14.3
|
|
1.527E-2
|
1.985E-2
|
6.313E-2
|
1.985E-1
|
1
|
41
|
11
|
1q32.1
|
1q32.1
|
|
4.193E-2
|
4.621E-2
|
1.469E-1
|
5.451E-1
|
1
|
114
|
12
|
7q22.1
|
7q22.1
|
|
4.265E-2
|
4.621E-2
|
1.469E-1
|
5.545E-1
|
1
|
116
|
Show 7 more annotations
|
11: Transcription Factor Binding Site [Display Chart]
12 input genes in category / 73 annotations before applied cutoff / 9770 genes in category
|
12: Gene Family [Display Chart]
9 input genes in category / 4 annotations before applied cutoff / 18194 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
415
|
V-type ATPases
|
genenames.org
|
2.434E-10
|
9.737E-10
|
2.029E-9
|
9.737E-10
|
4
|
23
|
2
|
1212
|
ATPase copper transporting
|
genenames.org
|
2.175E-7
|
4.350E-7
|
9.063E-7
|
8.701E-7
|
2
|
2
|
3
|
1209
|
ATPases Ca2+ transporting
|
genenames.org
|
7.817E-6
|
1.042E-5
|
2.171E-5
|
3.127E-5
|
2
|
9
|
4
|
1208
|
ATPase Na+/K+ transporting subunits
|
genenames.org
|
3.458E-3
|
3.458E-3
|
7.204E-3
|
1.383E-2
|
1
|
7
|
|
13: Coexpression [Display Chart]
13 input genes in category / 1185 annotations before applied cutoff / 23137 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
M4461
|
Genes down-regulated in comparison of monocytes cultured for 0 days versus those cultured for 7 days.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
3.645E-6
|
4.319E-3
|
3.306E-2
|
4.319E-3
|
4
|
200
|
2
|
19658189-TableS8d
|
Human EmbryonicStemCell Xu09 85genes
|
GeneSigDB
|
1.241E-5
|
7.350E-3
|
5.627E-2
|
1.470E-2
|
3
|
83
|
3
|
M1885
|
Genes down-regulated in vascular smooth muscle cells (VSMC) by MAPK8 (JNK1) [GeneID=5599].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.934E-5
|
1.268E-2
|
9.707E-2
|
4.662E-2
|
4
|
366
|
4
|
M1865
|
Up-regulated genes in the subpopulation of invasive PyMT cells (breast cancer) compared to the general population of PyMT cells.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
4.280E-5
|
1.268E-2
|
9.707E-2
|
5.072E-2
|
4
|
374
|
5
|
M6041
|
'Cancer prone response profile' (CPRP): genes changed in response to estradiol [PubChem=5757] in epithelial cell cultures from patients at high risk of breast cancer.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.093E-4
|
1.839E-2
|
1.408E-1
|
1.295E-1
|
2
|
28
|
6
|
20460173-ImmPortMemoryvsNaive
|
Human Immune Kong10 36genes ImmPort MemoryvsNaive
|
GeneSigDB
|
1.173E-4
|
1.839E-2
|
1.408E-1
|
1.390E-1
|
2
|
29
|
7
|
M8491
|
Genes up-regulated in B16 melanoma at day 3 of adoptive transfer treatment: mock versus therapy.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.707E-4
|
1.839E-2
|
1.408E-1
|
2.023E-1
|
3
|
200
|
8
|
M9491
|
Genes up-regulated in CD8 T cells during chronic infection with LCMV-Clone 13: effectors at day 8 versus exhausted at day 30.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.707E-4
|
1.839E-2
|
1.408E-1
|
2.023E-1
|
3
|
200
|
9
|
M5936
|
Genes encoding proteins involved in oxidative phosphorylation.
|
MSigDB H: Hallmark Gene Sets (v6.0)
|
1.707E-4
|
1.839E-2
|
1.408E-1
|
2.023E-1
|
3
|
200
|
10
|
M8539
|
Genes up-regulated in CD8 T cells: KLRB1 int [GeneID=3820] versus KLRB1- [GeneID=3820].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.707E-4
|
1.839E-2
|
1.408E-1
|
2.023E-1
|
3
|
200
|
11
|
M4503
|
Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus unstimulatd dendritic cells (DC).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.707E-4
|
1.839E-2
|
1.408E-1
|
2.023E-1
|
3
|
200
|
12
|
20371479-TableS2
|
Human Leukemia Saito10 259genes
|
GeneSigDB
|
3.064E-4
|
3.026E-2
|
2.316E-1
|
3.631E-1
|
3
|
244
|
13
|
M16977
|
Genes up-regulated in more than one of several human hepatoma cell lines by TSA [PubChem=5562].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.516E-4
|
3.097E-2
|
2.370E-1
|
4.167E-1
|
2
|
50
|
14
|
16356477-Table1
|
Human Breast Song06 62genes
|
GeneSigDB
|
3.658E-4
|
3.097E-2
|
2.370E-1
|
4.335E-1
|
2
|
51
|
15
|
M10332
|
Genes up-regulated in hyppocampus at late postnatal stages (clusters 11 and 15).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
5.583E-4
|
4.410E-2
|
3.376E-1
|
6.615E-1
|
2
|
63
|
16
|
M4001
|
Genes down-regulated in RD cells (embryonal rhabdomyosarcoma, ERMS) by expression of PAX3- or PAX7-FOXO1 [GeneID=5077;5081;2308] fusions off retroviral vectors.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
6.501E-4
|
4.815E-2
|
3.686E-1
|
7.704E-1
|
2
|
68
|
Show 11 more annotations
|
14: Coexpression Atlas [Display Chart]
13 input genes in category / 920 annotations before applied cutoff / 21829 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal RCC PT-U/Kidney Normal RCC PT16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal RCC PT-U/Kidney Normal RCC PT16
|
Adult, Development, and Cancer types
|
4.649E-8
|
4.277E-5
|
3.166E-4
|
4.277E-5
|
5
|
182
|
2
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal RCC F-U/Kidney Normal RCC F16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal RCC F-U/Kidney Normal RCC F16
|
Adult, Development, and Cancer types
|
5.779E-7
|
2.658E-4
|
1.968E-3
|
5.317E-4
|
4
|
119
|
3
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Medulla Wilms U U/Kidney Normal-Medulla Wilms U16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Medulla Wilms U U/Kidney Normal-Medulla Wilms U16
|
Adult, Development, and Cancer types
|
3.084E-6
|
5.383E-4
|
3.984E-3
|
2.837E-3
|
4
|
181
|
4
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Cortex Wilms U U/Kidney Normal-Cortex Wilms U16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Cortex Wilms U U/Kidney Normal-Cortex Wilms U16
|
Adult, Development, and Cancer types
|
3.152E-6
|
5.383E-4
|
3.984E-3
|
2.900E-3
|
4
|
182
|
5
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal RCC EN-B/Kidney Normal RCC EN16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal RCC EN-B/Kidney Normal RCC EN16
|
Adult, Development, and Cancer types
|
3.292E-6
|
5.383E-4
|
3.984E-3
|
3.029E-3
|
4
|
184
|
6
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Cortex Wilms Mast cell
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Cortex Wilms Mast cell
|
Adult, Development, and Cancer types
|
3.510E-6
|
5.383E-4
|
3.984E-3
|
3.230E-3
|
4
|
187
|
7
|
gudmap kidney single cell adult RenalCortexMixed Scamp k4 500
|
kidney single cell adult RenalCortexMixed StemCellamp k-means-cluster#4 top-relative-expression-ranked 500
|
Gudmap Mouse MOE430.2
|
6.504E-5
|
8.549E-3
|
6.328E-2
|
5.984E-2
|
4
|
393
|
8
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Medulla post-natal kidney NK cell/Kidney Normal-Medulla post-natal kidney NK16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Medulla post-natal kidney NK cell/Kidney Normal-Medulla post-natal kidney NK16
|
Adult, Development, and Cancer types
|
1.484E-4
|
8.561E-3
|
6.337E-2
|
1.365E-1
|
3
|
180
|
9
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex Wilms NK cell/Kidney Normal-Cortex Wilms NK16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex Wilms NK cell/Kidney Normal-Cortex Wilms NK16
|
Adult, Development, and Cancer types
|
1.484E-4
|
8.561E-3
|
6.337E-2
|
1.365E-1
|
3
|
180
|
10
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Medulla post-natal kidney Mast cell
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Mast cell/Kidney Normal-Medulla post-natal kidney Mast cell
|
Adult, Development, and Cancer types
|
1.508E-4
|
8.561E-3
|
6.337E-2
|
1.388E-1
|
3
|
181
|
11
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex post-natal kidney NK cell/Kidney Normal-Cortex post-natal kidney NK16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Cortex post-natal kidney NK cell/Kidney Normal-Cortex post-natal kidney NK16
|
Adult, Development, and Cancer types
|
1.508E-4
|
8.561E-3
|
6.337E-2
|
1.388E-1
|
3
|
181
|
12
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Proliferating NK cell/Kidney Normal-Cortex post-natal kidney Proliferating NK cell
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Proliferating NK cell/Kidney Normal-Cortex post-natal kidney Proliferating NK cell
|
Adult, Development, and Cancer types
|
1.533E-4
|
8.561E-3
|
6.337E-2
|
1.411E-1
|
3
|
182
|
13
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal-Cortex post-natal kidney R U/Kidney Normal-Cortex post-natal kidney R16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal-Cortex post-natal kidney R U/Kidney Normal-Cortex post-natal kidney R16
|
Adult, Development, and Cancer types
|
1.533E-4
|
8.561E-3
|
6.337E-2
|
1.411E-1
|
3
|
182
|
14
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal-Medulla Wilms PT-U/Kidney Normal-Medulla Wilms PT16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Normal-Medulla Wilms PT-U/Kidney Normal-Medulla Wilms PT16
|
Adult, Development, and Cancer types
|
1.533E-4
|
8.561E-3
|
6.337E-2
|
1.411E-1
|
3
|
182
|
15
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Normal-Medulla post-natal kidney IF-U/Kidney Normal-Medulla post-natal kidney IF16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Normal-Medulla post-natal kidney IF-U/Kidney Normal-Medulla post-natal kidney IF16
|
Adult, Development, and Cancer types
|
1.558E-4
|
8.561E-3
|
6.337E-2
|
1.434E-1
|
3
|
183
|
16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal-Cortex post-natal kidney EN-B/Kidney Normal-Cortex post-natal kidney EN16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal-Cortex post-natal kidney EN-B/Kidney Normal-Cortex post-natal kidney EN16
|
Adult, Development, and Cancer types
|
1.583E-4
|
8.561E-3
|
6.337E-2
|
1.457E-1
|
3
|
184
|
17
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N16
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N16
|
Adult, Development, and Cancer types
|
1.687E-4
|
8.561E-3
|
6.337E-2
|
1.552E-1
|
3
|
188
|
18
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N17
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium/Kidney Normal-Cortex Wilms N17
|
Adult, Development, and Cancer types
|
1.741E-4
|
8.561E-3
|
6.337E-2
|
1.602E-1
|
3
|
190
|
19
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Plasmacytoid DC/Kidney Normal-Cortex Wilms Plasmacytoid DC
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Plasmacytoid DC/Kidney Normal-Cortex Wilms Plasmacytoid DC
|
Adult, Development, and Cancer types
|
1.768E-4
|
8.561E-3
|
6.337E-2
|
1.627E-1
|
3
|
191
|
20
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Normal RCC EN-A/Kidney Normal RCC EN8
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Normal RCC EN-A/Kidney Normal RCC EN8
|
Adult, Development, and Cancer types
|
5.955E-4
|
2.739E-2
|
2.028E-1
|
5.479E-1
|
1
|
1
|
21
|
Facebase RNAseq e10.5 Neural Epithelium Overlying Medial Eminence 500 K1
|
FacebaseRNAseq e10.5 Neural Epithelium Overlying Medial Eminence top-relative-expression-ranked 500 k-means-cluster#1
|
FaceBase_RNAseq
|
1.008E-3
|
4.415E-2
|
3.268E-1
|
9.272E-1
|
2
|
80
|
Show 16 more annotations
|
15: Computational [Display Chart]
11 input genes in category / 82 annotations before applied cutoff / 10037 genes in category
|
16: MicroRNA [Display Chart]
13 input genes in category / 442 annotations before applied cutoff / 72241 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
hsa-miR-3666:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
3.495E-5
|
3.356E-3
|
2.238E-2
|
1.545E-2
|
3
|
364
|
2
|
hsa-miR-4295:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
3.552E-5
|
3.356E-3
|
2.238E-2
|
1.570E-2
|
3
|
366
|
3
|
hsa-miR-301b-3p:Non-Functional MTI
|
Non-Functional MTI
|
miRTarbase
|
3.818E-5
|
3.356E-3
|
2.238E-2
|
1.688E-2
|
3
|
375
|
4
|
hsa-miR-301a-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
4.455E-5
|
3.356E-3
|
2.238E-2
|
1.969E-2
|
3
|
395
|
5
|
hsa-miR-454-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
4.488E-5
|
3.356E-3
|
2.238E-2
|
1.984E-2
|
3
|
396
|
6
|
hsa-miR-130a-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
4.556E-5
|
3.356E-3
|
2.238E-2
|
2.014E-2
|
3
|
398
|
7
|
hsa-miR-886-3p:mirSVR lowEffct
|
hsa-miR-886-3p:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
7.597E-5
|
4.797E-3
|
3.199E-2
|
3.358E-2
|
3
|
473
|
8
|
hsa-miR-99a-5p:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.589E-4
|
1.431E-2
|
9.542E-2
|
1.144E-1
|
2
|
133
|
9
|
hsa-miR-490-3p:TargetScan
|
hsa-miR-490-3p
|
TargetScan
|
3.978E-4
|
1.954E-2
|
1.303E-1
|
1.758E-1
|
2
|
165
|
10
|
hsa-miR-1238:mirSVR highEffct
|
hsa-miR-1238:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
6.606E-4
|
2.288E-2
|
1.526E-1
|
2.920E-1
|
2
|
213
|
11
|
hsa-miR-649:PITA
|
hsa-miR-649:PITA TOP
|
PITA
|
6.606E-4
|
2.288E-2
|
1.526E-1
|
2.920E-1
|
2
|
213
|
12
|
hsa-miR-329:PITA
|
hsa-miR-329:PITA TOP
|
PITA
|
6.730E-4
|
2.288E-2
|
1.526E-1
|
2.975E-1
|
2
|
215
|
13
|
hsa-miR-362-3p:PITA
|
hsa-miR-362-3p:PITA TOP
|
PITA
|
6.730E-4
|
2.288E-2
|
1.526E-1
|
2.975E-1
|
2
|
215
|
14
|
ATGTTAA,MIR-302C:MSigDB
|
ATGTTAA,MIR-302C:MSigDB
|
MSigDB
|
7.825E-4
|
2.471E-2
|
1.648E-1
|
3.459E-1
|
2
|
232
|
15
|
hsa-miR-409-3p:PITA
|
hsa-miR-409-3p:PITA TOP
|
PITA
|
1.250E-3
|
3.091E-2
|
2.061E-1
|
5.525E-1
|
2
|
294
|
16
|
hsa-miR-196a-5p:Functional MTI
|
Functional MTI
|
miRTarbase
|
1.327E-3
|
3.091E-2
|
2.061E-1
|
5.863E-1
|
2
|
303
|
17
|
hsa-miR-513b:PITA
|
hsa-miR-513b:PITA TOP
|
PITA
|
1.505E-3
|
3.091E-2
|
2.061E-1
|
6.651E-1
|
2
|
323
|
18
|
hsa-miR-10a*:mirSVR highEffct
|
hsa-miR-10a*:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
1.588E-3
|
3.091E-2
|
2.061E-1
|
7.021E-1
|
2
|
332
|
19
|
hsa-miR-4321:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
1.619E-3
|
3.091E-2
|
2.061E-1
|
7.154E-1
|
1
|
9
|
20
|
hsa-miR-423-5p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
1.694E-3
|
3.091E-2
|
2.061E-1
|
7.486E-1
|
2
|
343
|
21
|
hsa-miR-519b-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
1.703E-3
|
3.091E-2
|
2.061E-1
|
7.529E-1
|
2
|
344
|
22
|
hsa-miR-519a-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
1.752E-3
|
3.091E-2
|
2.061E-1
|
7.746E-1
|
2
|
349
|
23
|
hsa-miR-519c-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
1.762E-3
|
3.091E-2
|
2.061E-1
|
7.790E-1
|
2
|
350
|
24
|
hsa-miR-572:mirSVR lowEffct
|
hsa-miR-572:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
1.792E-3
|
3.091E-2
|
2.061E-1
|
7.921E-1
|
2
|
353
|
25
|
hsa-miR-148b-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.325E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
403
|
26
|
hsa-miR-6082:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
2.337E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
1
|
13
|
27
|
hsa-miR-888:PITA
|
hsa-miR-888:PITA TOP
|
PITA
|
2.521E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
420
|
28
|
hsa-miR-1250-5p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
2.696E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
1
|
15
|
29
|
hsa-miR-611:mirSVR lowEffct
|
hsa-miR-611:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
2.725E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
437
|
30
|
hsa-miR-448:PITA
|
hsa-miR-448:PITA TOP
|
PITA
|
2.737E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
438
|
31
|
hsa-miR-302e:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
2.861E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
448
|
32
|
hsa-miR-520d-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.873E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
449
|
33
|
hsa-miR-555:mirSVR highEffct
|
hsa-miR-555:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
2.898E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
451
|
34
|
hsa-miR-802:PITA
|
hsa-miR-802:PITA TOP
|
PITA
|
2.911E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
452
|
35
|
hsa-miR-520e:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.923E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
453
|
36
|
hsa-miR-520a-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.949E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
455
|
37
|
hsa-miR-520c-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.949E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
455
|
38
|
hsa-miR-520b:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.949E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
455
|
39
|
hsa-miR-26a-5p:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.974E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
457
|
40
|
hsa-miR-103-as:mirSVR highEffct
|
hsa-miR-103-as:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
2.987E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
458
|
41
|
hsa-miR-302b-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
3.012E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
460
|
42
|
hsa-miR-302d-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
3.012E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
460
|
43
|
hsa-miR-372-3p:Non-Functional MTI
|
Non-Functional MTI
|
miRTarbase
|
3.025E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
461
|
44
|
hsa-miR-302a-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
3.077E-3
|
3.091E-2
|
2.061E-1
|
1.000E0
|
2
|
465
|
45
|
hsa-miR-148a:PITA
|
hsa-miR-148a:PITA TOP
|
PITA
|
3.314E-3
|
3.164E-2
|
2.110E-1
|
1.000E0
|
2
|
483
|
46
|
hsa-miR-302c-3p.2:TargetScan
|
hsa-miR-302c-3p.2
|
TargetScan
|
3.435E-3
|
3.164E-2
|
2.110E-1
|
1.000E0
|
2
|
492
|
47
|
hsa-miR-3131:mirSVR lowEffct
|
hsa-miR-3131:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
3.435E-3
|
3.164E-2
|
2.110E-1
|
1.000E0
|
2
|
492
|
48
|
hsa-miR-520f-3p:TargetScan
|
hsa-miR-520f-3p
|
TargetScan
|
3.435E-3
|
3.164E-2
|
2.110E-1
|
1.000E0
|
2
|
492
|
49
|
hsa-miR-4523:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
3.593E-3
|
3.241E-2
|
2.162E-1
|
1.000E0
|
1
|
20
|
50
|
hsa-miR-1250:PITA
|
hsa-miR-1250:PITA TOP
|
PITA
|
5.207E-3
|
4.603E-2
|
3.070E-1
|
1.000E0
|
1
|
29
|
Show 45 more annotations
|
17: Drug [Display Chart]
13 input genes in category / 3716 annotations before applied cutoff / 22841 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
CID000002287
|
NSC381866
|
Stitch
|
9.946E-15
|
3.696E-11
|
3.252E-10
|
3.696E-11
|
8
|
170
|
2
|
CID000004591
|
AC1L1IIA
|
Stitch
|
2.006E-12
|
3.728E-9
|
3.279E-8
|
7.455E-9
|
7
|
172
|
3
|
CID000010868
|
DCCD
|
Stitch
|
1.248E-10
|
1.545E-7
|
1.360E-6
|
4.636E-7
|
6
|
151
|
4
|
CID000061672
|
orthovanadate
|
Stitch
|
1.346E-9
|
1.251E-6
|
1.100E-5
|
5.003E-6
|
7
|
435
|
5
|
CID000384608
|
AC1L8NTU
|
Stitch
|
2.817E-9
|
2.093E-6
|
1.842E-5
|
1.047E-5
|
5
|
109
|
6
|
CID000023990
|
vanadium
|
Stitch
|
1.363E-8
|
8.439E-6
|
7.425E-5
|
5.064E-5
|
5
|
149
|
7
|
CID000415541
|
IN1025
|
Stitch
|
1.130E-7
|
6.000E-5
|
5.279E-4
|
4.200E-4
|
4
|
83
|
8
|
CID000024411
|
oxovanadium
|
Stitch
|
4.994E-7
|
2.320E-4
|
2.041E-3
|
1.856E-3
|
4
|
120
|
9
|
CID000033558
|
azide
|
Stitch
|
2.523E-6
|
1.042E-3
|
9.165E-3
|
9.376E-3
|
4
|
180
|
10
|
ctd:C081294
|
satraplatin
|
CTD
|
2.987E-6
|
1.110E-3
|
9.767E-3
|
1.110E-2
|
2
|
5
|
11
|
CID000124822
|
copper histidinate
|
Stitch
|
4.597E-6
|
1.553E-3
|
1.366E-2
|
1.708E-2
|
3
|
59
|
12
|
CID000000832
|
L-beta-aspartyl phosphate
|
Stitch
|
7.384E-6
|
2.287E-3
|
2.012E-2
|
2.744E-2
|
3
|
69
|
13
|
CID011953896
|
2,3-Isoprolylideneerthrofuranosyl 2,3-O-isopropylideneerythrofuranoside
|
Stitch
|
1.074E-5
|
3.070E-3
|
2.701E-2
|
3.991E-2
|
2
|
9
|
14
|
CID000444279
|
1sqc
|
Stitch
|
1.342E-5
|
3.563E-3
|
3.134E-2
|
4.988E-2
|
2
|
10
|
15
|
CID000008718
|
2,5-dimethylquinone
|
Stitch
|
1.640E-5
|
4.063E-3
|
3.574E-2
|
6.094E-2
|
2
|
11
|
16
|
CID000013245
|
AC1MMLID
|
Stitch
|
1.756E-5
|
4.079E-3
|
3.589E-2
|
6.527E-2
|
3
|
92
|
17
|
CID004369390
|
1vyq
|
Stitch
|
1.967E-5
|
4.300E-3
|
3.783E-2
|
7.310E-2
|
2
|
12
|
18
|
CID000000186
|
acetyl phosphate
|
Stitch
|
2.123E-5
|
4.383E-3
|
3.856E-2
|
7.890E-2
|
3
|
98
|
19
|
CID000151012
|
p-hydroxyhippuric acid
|
Stitch
|
2.711E-5
|
5.302E-3
|
4.664E-2
|
1.007E-1
|
2
|
14
|
20
|
ctd:D016190
|
Carboplatin
|
CTD
|
3.252E-5
|
6.016E-3
|
5.293E-2
|
1.209E-1
|
3
|
113
|
21
|
CID016040251
|
PE-W
|
Stitch
|
3.572E-5
|
6.016E-3
|
5.293E-2
|
1.327E-1
|
2
|
16
|
22
|
CID000014974
|
Ostreogrycin B
|
Stitch
|
3.572E-5
|
6.016E-3
|
5.293E-2
|
1.327E-1
|
2
|
16
|
23
|
CID000374551
|
AC1L88YH
|
Stitch
|
4.047E-5
|
6.016E-3
|
5.293E-2
|
1.504E-1
|
2
|
17
|
24
|
CID011979418
|
RP 59500
|
Stitch
|
4.047E-5
|
6.016E-3
|
5.293E-2
|
1.504E-1
|
2
|
17
|
25
|
CID011979535
|
Mikamycine
|
Stitch
|
4.047E-5
|
6.016E-3
|
5.293E-2
|
1.504E-1
|
2
|
17
|
26
|
CID000002603
|
carbonyl cyanide m-chlorophenylhydrazone
|
Stitch
|
4.396E-5
|
6.264E-3
|
5.511E-2
|
1.634E-1
|
3
|
125
|
27
|
CID000010104
|
NSC 234205
|
Stitch
|
4.552E-5
|
6.264E-3
|
5.511E-2
|
1.691E-1
|
2
|
18
|
28
|
CID000091599
|
aluminum citrate
|
Stitch
|
5.649E-5
|
7.238E-3
|
6.368E-2
|
2.099E-1
|
2
|
20
|
29
|
ctd:D010984
|
Platinum
|
CTD
|
5.649E-5
|
7.238E-3
|
6.368E-2
|
2.099E-1
|
2
|
20
|
30
|
CID000015465
|
AC1L25Y6
|
Stitch
|
7.515E-5
|
9.008E-3
|
7.925E-2
|
2.792E-1
|
2
|
23
|
31
|
CID000165791
|
lanthanum chloride hydrate
|
Stitch
|
7.515E-5
|
9.008E-3
|
7.925E-2
|
2.792E-1
|
2
|
23
|
32
|
CID000024854
|
CaCl2
|
Stitch
|
8.500E-5
|
9.870E-3
|
8.684E-2
|
3.159E-1
|
3
|
156
|
33
|
CID005364545
|
cyhexatin
|
Stitch
|
8.905E-5
|
1.003E-2
|
8.822E-2
|
3.309E-1
|
2
|
25
|
34
|
CID000020667
|
dodecyl ether
|
Stitch
|
9.644E-5
|
1.054E-2
|
9.273E-2
|
3.584E-1
|
2
|
26
|
35
|
CID000454923
|
XK234
|
Stitch
|
1.040E-4
|
1.075E-2
|
9.455E-2
|
3.866E-1
|
3
|
167
|
36
|
CID006914595
|
Bi-E
|
Stitch
|
1.041E-4
|
1.075E-2
|
9.455E-2
|
3.869E-1
|
2
|
27
|
37
|
ctd:D003958
|
Diamide
|
CTD
|
1.121E-4
|
1.126E-2
|
9.904E-2
|
4.165E-1
|
2
|
28
|
38
|
CID000078798
|
octaethylene glycol
|
Stitch
|
1.204E-4
|
1.177E-2
|
1.035E-1
|
4.472E-1
|
2
|
29
|
39
|
CID006434704
|
Ormaplatino
|
Stitch
|
1.378E-4
|
1.258E-2
|
1.107E-1
|
5.119E-1
|
2
|
31
|
40
|
CID006436102
|
NF T
|
Stitch
|
1.524E-4
|
1.258E-2
|
1.107E-1
|
5.663E-1
|
3
|
190
|
41
|
7053 DN
|
thapsigargin; Down 200; 0.1uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Down
|
1.524E-4
|
1.258E-2
|
1.107E-1
|
5.663E-1
|
3
|
190
|
42
|
CID000104406
|
E1-P
|
Stitch
|
1.563E-4
|
1.258E-2
|
1.107E-1
|
5.809E-1
|
2
|
33
|
43
|
3861 DN
|
Proglumide [6620-60-6]; Down 200; 12uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Down
|
1.621E-4
|
1.258E-2
|
1.107E-1
|
6.022E-1
|
3
|
194
|
44
|
3526 UP
|
Tridihexethyl chloride; Up 200; 11.4uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Up
|
1.621E-4
|
1.258E-2
|
1.107E-1
|
6.022E-1
|
3
|
194
|
45
|
5241 UP
|
haloperidol; Up 200; 10uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Up
|
1.645E-4
|
1.258E-2
|
1.107E-1
|
6.114E-1
|
3
|
195
|
46
|
1445 UP
|
Meclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; HL60; HG-U133A
|
Broad Institute CMAP Up
|
1.670E-4
|
1.258E-2
|
1.107E-1
|
6.207E-1
|
3
|
196
|
47
|
4974 UP
|
Arcaine sulfate [14923-17-2]; Up 200; 14.8uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Up
|
1.670E-4
|
1.258E-2
|
1.107E-1
|
6.207E-1
|
3
|
196
|
48
|
4125 DN
|
Aspartic acid, N-acetyl (R,S) [997-55-7]; Down 200; 22.8uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Down
|
1.670E-4
|
1.258E-2
|
1.107E-1
|
6.207E-1
|
3
|
196
|
49
|
7450 DN
|
Levamisole hydrochloride [16595-80-5]; Down 200; 16.6uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Down
|
1.721E-4
|
1.258E-2
|
1.107E-1
|
6.396E-1
|
3
|
198
|
50
|
3249 UP
|
Thyroxine (L) [51-48-9]; Up 200; 5.2uM; MCF7; HT HG-U133A
|
Broad Institute CMAP Up
|
1.747E-4
|
1.258E-2
|
1.107E-1
|
6.491E-1
|
3
|
199
|
Show 45 more annotations
|
18: Disease [Display Chart]
13 input genes in category / 449 annotations before applied cutoff / 16205 genes in category
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
C0012714
|
Disorder of copper metabolism
|
DisGeNET BeFree
|
1.613E-9
|
7.240E-7
|
4.840E-6
|
7.240E-7
|
3
|
4
|
2
|
C0268070
|
Hypocupremia
|
DisGeNET Curated
|
2.725E-7
|
6.117E-5
|
4.090E-4
|
1.223E-4
|
3
|
17
|
3
|
C0022716
|
Menkes Kinky Hair Syndrome
|
DisGeNET Curated
|
2.219E-4
|
1.162E-2
|
7.768E-2
|
9.965E-2
|
2
|
28
|
4
|
C1836330
|
ERYTHROKERATODERMIA VARIABILIS 3 (disorder)
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
5
|
cv:C1832918
|
Brody myopathy
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
6
|
C4024907
|
Mixed demyelinating and axonal polyneuropathy
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
7
|
cv:C1836330
|
Erythrokeratodermia variabilis 3
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
8
|
cv:CN181443
|
Parkinsonism with spasticity, X-linked
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
9
|
C4025211
|
Abnormality of the carotid arteries
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
10
|
C4280490
|
Low hanging nasal septum
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
11
|
cv:C0019202
|
Wilson's disease
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
12
|
OMIN:277900
|
WILSON DISEASE
|
OMIM
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
13
|
C1848456
|
Atypical or prolonged hepatitis
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
14
|
cv:C1864498
|
Renal tubular acidosis, distal, autosomal recessive
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
15
|
OMIN:300489
|
SPINAL MUSCULAR ATROPHY, DISTAL, X-LINKED 3; SMAX3
|
OMIM
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
16
|
C1845543
|
Mental Retardation, X-Linked, with Epilepsy
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
17
|
OMIN:304150
|
OCCIPITAL HORN SYNDROME; OHS
|
OMIM
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
18
|
cv:C1845543
|
Mental retardation, X-linked, syndromic, Hedera type
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
19
|
cv:C0022716
|
Menkes kinky-hair syndrome
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
20
|
OMIN:601003
|
BRODY MYOPATHY
|
OMIM
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
21
|
cv:C1845359
|
Distal spinal muscular atrophy, X-linked 3
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
22
|
cv:C0268353
|
Cutis laxa, X-linked
|
Clinical Variations
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
23
|
C4025216
|
Prominent nasal septum
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
24
|
C1303076
|
Tortuous carotid artery
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
25
|
C4225321
|
ZIMMERMANN-LABAND SYNDROME 2
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
26
|
C1845359
|
Spinal Muscular Atrophy, Distal, X-Linked 3
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
27
|
C1876166
|
Endemic Tyrolean Infantile Cirrhosis
|
DisGeNET BeFree
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
28
|
C2675730
|
Deafness, Congenital, and Onychodystrophy, Autosomal Dominant
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
29
|
C4280489
|
Visible nasal septum
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
30
|
C1848459
|
High nonceruloplasmin-bound serum copper
|
DisGeNET Curated
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
31
|
OMIN:309400
|
MENKES DISEASE
|
OMIM
|
8.022E-4
|
1.162E-2
|
7.768E-2
|
3.602E-1
|
1
|
1
|
32
|
C0026946
|
Mycoses
|
DisGeNET BeFree
|
9.147E-4
|
1.258E-2
|
8.413E-2
|
4.107E-1
|
3
|
249
|
33
|
C1384514
|
Conn Syndrome
|
DisGeNET BeFree
|
9.249E-4
|
1.258E-2
|
8.413E-2
|
4.153E-1
|
2
|
57
|
34
|
C0019202
|
Hepatolenticular Degeneration
|
DisGeNET Curated
|
1.238E-3
|
1.532E-2
|
1.024E-1
|
5.558E-1
|
2
|
66
|
35
|
C0031117
|
Peripheral Neuropathy
|
DisGeNET Curated
|
1.244E-3
|
1.532E-2
|
1.024E-1
|
5.588E-1
|
3
|
277
|
36
|
C0423798
|
Increased tendency to bruise
|
DisGeNET Curated
|
1.275E-3
|
1.532E-2
|
1.024E-1
|
5.727E-1
|
2
|
67
|
37
|
C0013491
|
Ecchymosis
|
DisGeNET Curated
|
1.275E-3
|
1.532E-2
|
1.024E-1
|
5.727E-1
|
2
|
67
|
38
|
C0151564
|
Cogwheel Rigidity
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
39
|
C0679145
|
sexual addiction
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
40
|
C4025831
|
Abnormal peripheral nervous system morphology
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
41
|
C1848453
|
Poor motor coordination
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
42
|
C0152457
|
Kayser-Fleischer ring
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
43
|
OMIN:602722
|
RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE; RTADR
|
OMIM
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
44
|
OMIN:609015
|
TRIFUNCTIONAL PROTEIN DEFICIENCY
|
OMIM
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
45
|
C1832988
|
Metaphyseal spurs
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
46
|
cv:C0342786
|
Mitochondrial trifunctional protein deficiency
|
Clinical Variations
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
47
|
C3806722
|
PARKINSONISM WITH SPASTICITY, X-LINKED
|
DisGeNET Curated
|
1.604E-3
|
1.532E-2
|
1.024E-1
|
7.201E-1
|
1
|
2
|
48
|
C0438237
|
Liver enzymes abnormal
|
DisGeNET Curated
|
1.857E-3
|
1.544E-2
|
1.032E-1
|
8.339E-1
|
2
|
81
|
49
|
C0151766
|
Liver function tests abnormal finding
|
DisGeNET Curated
|
1.857E-3
|
1.544E-2
|
1.032E-1
|
8.339E-1
|
2
|
81
|
50
|
C1842003
|
Subclinical abnormal liver function tests
|
DisGeNET Curated
|
1.857E-3
|
1.544E-2
|
1.032E-1
|
8.339E-1
|
2
|
81
|
Show 45 more annotations
|
|