|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
29048604
|
Influence of DARPP-32 genetic variation on BOLD activation to happy faces.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
2
|
25846879
|
The effect of high glucose levels on the hypermethylation of protein phosphatase 1 regulatory subunit 3C (PPP1R3C) gene in colorectal cancer.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
3
|
7581368
|
A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
4
|
16431080
|
Characterization and function of MYPT2, a target subunit of myosin phosphatase in heart.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
5
|
15522888
|
Migration and retraction of endothelial and epithelial cells require PHI-1, a specific protein-phosphatase-1 inhibitor protein.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
6
|
19463699
|
The biological basis of anger: associations with the gene coding for DARPP-32 (PPP1R1B) and with amygdala volume.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
7
|
16061638
|
Darpp-32: a novel antiapoptotic gene in upper gastrointestinal carcinomas.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
8
|
15188007
|
DARPP-32 expression arises after a phase of dysplasia in oesophageal squamous cell carcinoma.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
9
|
21821092
|
Profiles of DARPP-32 in the insular cortex with schizophrenia: a postmortem brain study.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
10
|
12941760
|
Regulation and function of the muscle glycogen-targeting subunit of protein phosphatase 1 (GM) in human muscle cells depends on the COOH-terminal region and glycogen content.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
11
|
22777184
|
Constitutive phosphorylation of inhibitor-1 at Ser67 and Thr75 depresses calcium cycling in cardiomyocytes and leads to remodeling upon aging.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
12
|
10103106
|
Neuronal and behavioural abnormalities in striatal function in DARPP-32-mutant mice.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
13
|
1791981
|
Dopamine- and adenosine-3':5'-monophosphate (cAMP)-regulated phosphoprotein of Mr 32,000 (DARPP-32) in the retina of cat, monkey and human.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
14
|
24058659
|
Spatial distribution of DARPP-32 in dendritic spines.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
15
|
8838322
|
Isolation and characterization of a novel gene close to the human phosphoinositide-specific phospholipase C beta 3 gene on chromosomal region 11q13.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
16
|
11150351
|
Motivational effects of ethanol in DARPP-32 knock-out mice.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
17
|
11722604
|
Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
18
|
25692798
|
Dendritic geometry shapes neuronal cAMP signalling to the nucleus.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
19
|
19050854
|
A role for casein kinase 1 epsilon in the locomotor stimulant response to methamphetamine.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
20
|
22179181
|
Detailed DARPP-32 expression profiles in postmortem brains from patients with schizophrenia: an immunohistochemical study.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
21
|
11812771
|
KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
22
|
17171661
|
Association analysis of the protein phosphatase 1 regulatory subunit 1B (PPP1R1B) gene with nicotine dependence in European- and African-American smokers.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
23
|
15657149
|
Glutamate regulation of DARPP-32 phosphorylation in neostriatal neurons involves activation of multiple signaling cascades.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
24
|
18055181
|
Genetic analysis of the gene coding for DARPP-32 (PPP1R1B) in Japanese patients with schizophrenia or bipolar disorder.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
25
|
18234908
|
Disruption of the striated muscle glycogen-targeting subunit of protein phosphatase 1: influence of the genetic background.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
26
|
21453742
|
Altered DARPP-32 expression in the superior temporal gyrus in schizophrenia.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
27
|
1721636
|
Dopamine- and adenosine-3',5'-monophosphate (cAMP)-regulated phosphoprotein of 32 kDa (DARPP-32) in the adrenal gland: immunohistochemical localization.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
28
|
18232732
|
A prevalent variant in PPP1R3A impairs glycogen synthesis and reduces muscle glycogen content in humans and mice.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
29
|
17596448
|
Critical involvement of cAMP/DARPP-32 and extracellular signal-regulated protein kinase signaling in L-DOPA-induced dyskinesia.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
30
|
21738631
|
A PTG variant contributes to a milder phenotype in Lafora disease.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
31
|
27995567
|
Associations Between PPP1R1B Gene Polymorphisms and Anxiety Levels in the Chinese Population.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
32
|
11880652
|
DARPP-32 mediates serotonergic neurotransmission in the forebrain.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
33
|
18579663
|
Expression of t-DARPP mediates trastuzumab resistance in breast cancer cells.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
34
|
6319627
|
DARPP-32, a dopamine- and adenosine 3':5'-monophosphate-regulated phosphoprotein enriched in dopamine-innervated brain regions. I. Regional and cellular distribution in the rat brain.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
35
|
1533862
|
Regional distribution of DARPP-32 (dopamine- and adenosine 3',5'-monophosphate-regulated phosphoprotein of Mr = 32,000) mRNA in mouse brain.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
36
|
16971527
|
DARPP-32 involvement in the photic pathway of the circadian system.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
37
|
16750903
|
Mutation analysis of DARPP-32 as a candidate gene for schizophrenia.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
38
|
2191086
|
Distribution of DARPP-32 in the basal ganglia: an electron microscopic study.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
39
|
10837805
|
DARPP-32 knockout mice exhibit impaired reversal learning in a discriminated operant task.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
40
|
10606530
|
A novel phosphoprotein inhibitor of protein type-1 phosphatase holoenzymes.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
41
|
10669419
|
Requirement for DARPP-32 in progesterone-facilitated sexual receptivity in female rats and mice.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
42
|
23906769
|
Methylphenidate restores novel object recognition in DARPP-32 knockout mice.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
43
|
21369787
|
Association between DARPP-32 gene polymorphism and personality traits in healthy Chinese-Han subjects.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
44
|
11522787
|
The muscle-specific protein phosphatase PP1G/R(GL)(G(M))is essential for activation of glycogen synthase by exercise.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
45
|
7926294
|
Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
46
|
9726244
|
A common variant in PPP1R3 associated with insulin resistance and type 2 diabetes.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
47
|
14767904
|
[Study on association of PPP1R3 gene 5 bp deletion/insertion within 3'-untranslated region polymorphism with type 2 diabetes].
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
48
|
17257813
|
The skeletal muscle-specific glycogen-targeted protein phosphatase 1 plays a major role in the regulation of glycogen metabolism by adrenaline in vivo.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
49
|
16525043
|
Cocaine self-administration in mice is inversely related to phosphorylation at Thr34 (protein kinase A site) and Ser130 (kinase CK1 site) of DARPP-32.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|
50
|
11069952
|
Dopamine and cAMP-regulated phosphoprotein 32 kDa controls both striatal long-term depression and long-term potentiation, opposing forms of synaptic plasticity.
|
Pubmed
|
1.571E-4
|
4.116E-4
|
2.635E-3
|
5.310E-2
|
1
|
1
|