Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc282_16, positive side

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1: GO: Molecular Function [Display Chart] 16 input genes in category / 102 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016209 antioxidant activity 6.493E-16 6.623E-14 3.449E-13 6.623E-14 8 76
2 GO:0004601 peroxidase activity 3.271E-15 1.540E-13 8.019E-13 3.336E-13 7 45
3 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 4.530E-15 1.540E-13 8.019E-13 4.620E-13 7 47
4 GO:0008379 thioredoxin peroxidase activity 1.033E-8 2.633E-7 1.371E-6 1.053E-6 3 6
5 GO:0051920 peroxiredoxin activity 2.888E-8 5.892E-7 3.068E-6 2.946E-6 3 8
6 GO:0020037 heme binding 3.954E-6 6.722E-5 3.500E-4 4.033E-4 4 131
7 GO:0046906 tetrapyrrole binding 5.150E-6 7.504E-5 3.907E-4 5.253E-4 4 140
8 GO:0050661 NADP binding 8.736E-6 1.114E-4 5.800E-4 8.911E-4 3 48
9 GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor 3.089E-5 3.501E-4 1.823E-3 3.151E-3 2 10
10 GO:0043295 glutathione binding 7.190E-5 7.334E-4 3.819E-3 7.334E-3 2 15
11 GO:1900750 oligopeptide binding 8.213E-5 7.378E-4 3.842E-3 8.377E-3 2 16
12 GO:0016651 oxidoreductase activity, acting on NAD(P)H 8.680E-5 7.378E-4 3.842E-3 8.853E-3 3 103
13 GO:0050662 coenzyme binding 5.440E-4 4.268E-3 2.223E-2
5.549E-2
 3 192
14 GO:0004362 glutathione-disulfide reductase activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
15 GO:0004092 carnitine O-acetyltransferase activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
16 GO:0047560 3-dehydrosphinganine reductase activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
17 GO:0044594 17-beta-hydroxysteroid dehydrogenase (NAD+) activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
18 GO:0043843 ADP-specific glucokinase activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
19 GO:0050313 sulfur dioxygenase activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
20 GO:0033989 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity 8.574E-4 4.373E-3 2.277E-2
8.746E-2
 1 1
21 GO:0016667 oxidoreductase activity, acting on a sulfur group of donors 9.258E-4 4.497E-3 2.342E-2
9.444E-2
 2 53
22 GO:1901681 sulfur compound binding 1.309E-3 6.069E-3 3.160E-2
1.335E-1
 3 260
23 GO:0048037 cofactor binding 1.570E-3 6.476E-3 3.372E-2
1.601E-1
 3 277
24 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity 1.714E-3 6.476E-3 3.372E-2
1.748E-1
 1 2
25 GO:0031753 endothelial differentiation G protein-coupled receptor binding 1.714E-3 6.476E-3 3.372E-2
1.748E-1
 1 2
26 GO:0008785 alkyl hydroperoxide reductase activity 1.714E-3 6.476E-3 3.372E-2
1.748E-1
 1 2
27 GO:0031755 Edg-2 lysophosphatidic acid receptor binding 1.714E-3 6.476E-3 3.372E-2
1.748E-1
 1 2
28 GO:0072341 modified amino acid binding 1.796E-3 6.542E-3 3.406E-2
1.832E-1
 2 74
29 GO:0004096 catalase activity 2.570E-3 9.040E-3 4.707E-2
2.622E-1
 1 3
30 GO:0047696 beta-adrenergic receptor kinase activity 3.425E-3 1.127E-2
5.869E-2
3.494E-1
 1 4
31 GO:0016508 long-chain-enoyl-CoA hydratase activity 3.425E-3 1.127E-2
5.869E-2
3.494E-1
 1 4
32 GO:0004046 aminoacylase activity 4.280E-3 1.247E-2
6.495E-2
4.366E-1
 1 5
33 GO:0015038 glutathione disulfide oxidoreductase activity 4.280E-3 1.247E-2
6.495E-2
4.366E-1
 1 5
34 GO:0018812 3-hydroxyacyl-CoA dehydratase activity 4.280E-3 1.247E-2
6.495E-2
4.366E-1
 1 5
35 GO:0031694 alpha-2A adrenergic receptor binding 4.280E-3 1.247E-2
6.495E-2
4.366E-1
 1 5
36 GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 4.639E-3 1.314E-2
6.845E-2
4.732E-1
 2 120
37 GO:0016174 NAD(P)H oxidase activity 5.987E-3 1.566E-2
8.154E-2
6.107E-1
 1 7
38 GO:0015037 peptide disulfide oxidoreductase activity 5.987E-3 1.566E-2
8.154E-2
6.107E-1
 1 7
39 GO:0004703 G protein-coupled receptor kinase activity 5.987E-3 1.566E-2
8.154E-2
6.107E-1
 1 7
40 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors 6.789E-3 1.731E-2
9.015E-2
6.925E-1
 2 146
41 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 6.970E-3 1.734E-2
9.029E-2
7.110E-1
 2 148
42 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity 7.692E-3 1.868E-2
9.727E-2
7.846E-1
 1 9
43 GO:0008430 selenium binding 9.394E-3 2.228E-2
1.160E-1
9.581E-1
 1 11
44 GO:0004303 estradiol 17-beta-dehydrogenase activity 1.194E-2 2.768E-2
1.441E-1
1.000E0
 1 14
45 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1.448E-2 3.283E-2
1.709E-1
1.000E0
 1 17
46 GO:0015269 calcium-activated potassium channel activity 1.533E-2 3.399E-2
1.770E-1
1.000E0
 1 18
47 GO:0070008 serine-type exopeptidase activity 1.617E-2 3.510E-2
1.828E-1
1.000E0
 1 19
48 GO:0031690 adrenergic receptor binding 1.702E-2 3.542E-2
1.845E-1
1.000E0
 1 20
49 GO:0004602 glutathione peroxidase activity 1.702E-2 3.542E-2
1.845E-1
1.000E0
 1 20
50 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process 2.123E-2 4.331E-2
2.255E-1
1.000E0
 1 25
Show 45 more annotations

2: GO: Biological Process [Display Chart] 16 input genes in category / 531 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0098869 cellular oxidant detoxification 2.037E-15 6.848E-13 4.693E-12 1.081E-12 8 87
2 GO:1990748 cellular detoxification 2.698E-15 6.848E-13 4.693E-12 1.433E-12 8 90
3 GO:0098754 detoxification 3.869E-15 6.848E-13 4.693E-12 2.055E-12 8 94
4 GO:0042744 hydrogen peroxide catabolic process 2.428E-14 3.224E-12 2.209E-11 1.289E-11 6 25
5 GO:0042743 hydrogen peroxide metabolic process 2.154E-12 2.288E-10 1.568E-9 1.144E-9 6 50
6 GO:0009636 response to toxic substance 1.989E-11 1.760E-9 1.206E-8 1.056E-8 8 269
7 GO:0006979 response to oxidative stress 9.761E-10 6.862E-8 4.703E-7 5.183E-7 8 439
8 GO:0072593 reactive oxygen species metabolic process 1.034E-9 6.862E-8 4.703E-7 5.490E-7 7 262
9 GO:0006575 cellular modified amino acid metabolic process 3.671E-8 2.166E-6 1.484E-5 1.949E-5 6 247
10 GO:0000302 response to reactive oxygen species 1.686E-6 8.953E-5 6.136E-4 8.953E-4 5 252
11 GO:0006801 superoxide metabolic process 1.817E-5 8.769E-4 6.009E-3 9.646E-3 3 61
12 GO:0006749 glutathione metabolic process 2.520E-5 1.115E-3 7.643E-3 1.338E-2 3 68
13 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase 5.368E-5 2.193E-3 1.503E-2 2.851E-2 2 13
14 GO:0006590 thyroid hormone generation 1.050E-4 3.984E-3 2.730E-2
5.577E-2
 2 18
15 GO:0019430 removal of superoxide radicals 1.889E-4 6.687E-3 4.583E-2
1.003E-1
 2 24
16 GO:0042403 thyroid hormone metabolic process 2.052E-4 6.811E-3 4.668E-2
1.090E-1
 2 25
17 GO:0071451 cellular response to superoxide 2.399E-4 7.077E-3 4.850E-2
1.274E-1
 2 27
18 GO:0071450 cellular response to oxygen radical 2.399E-4 7.077E-3 4.850E-2
1.274E-1
 2 27
19 GO:0034614 cellular response to reactive oxygen species 2.604E-4 7.278E-3 4.987E-2
1.383E-1
 3 149
20 GO:0000303 response to superoxide 2.968E-4 7.794E-3
5.341E-2
1.576E-1
 2 30
21 GO:0000305 response to oxygen radical 3.172E-4 7.794E-3
5.341E-2
1.684E-1
 2 31
22 GO:0006790 sulfur compound metabolic process 3.229E-4 7.794E-3
5.341E-2
1.715E-1
 4 404
23 GO:0043901 negative regulation of multi-organism process 3.576E-4 8.257E-3
5.658E-2
1.899E-1
 3 166
24 GO:0048608 reproductive structure development 6.346E-4 1.390E-2
9.528E-2
3.370E-1
 4 483
25 GO:0061458 reproductive system development 6.546E-4 1.390E-2
9.528E-2
3.476E-1
 4 487
26 GO:0042445 hormone metabolic process 6.908E-4 1.411E-2
9.668E-2
3.668E-1
 3 208
27 GO:0043903 regulation of symbiosis, encompassing mutualism through parasitism 8.129E-4 1.426E-2
9.770E-2
4.316E-1
 3 220
28 GO:0006666 3-keto-sphinganine metabolic process 8.592E-4 1.426E-2
9.770E-2
4.562E-1
 1 1
29 GO:0002148 hypochlorous acid metabolic process 8.592E-4 1.426E-2
9.770E-2
4.562E-1
 1 1
30 GO:0002149 hypochlorous acid biosynthetic process 8.592E-4 1.426E-2
9.770E-2
4.562E-1
 1 1
31 GO:0036111 very long-chain fatty-acyl-CoA metabolic process 8.592E-4 1.426E-2
9.770E-2
4.562E-1
 1 1
32 GO:0003108 negative regulation of the force of heart contraction by chemical signal 8.592E-4 1.426E-2
9.770E-2
4.562E-1
 1 1
33 GO:0034599 cellular response to oxidative stress 1.136E-3 1.828E-2
1.253E-1
6.032E-1
 3 247
34 GO:0008406 gonad development 1.190E-3 1.858E-2
1.273E-1
6.318E-1
 3 251
35 GO:0045137 development of primary sexual characteristics 1.259E-3 1.910E-2
1.309E-1
6.687E-1
 3 256
36 GO:0045454 cell redox homeostasis 1.570E-3 2.316E-2
1.587E-1
8.336E-1
 2 69
37 GO:0006635 fatty acid beta-oxidation 1.661E-3 2.339E-2
1.603E-1
8.822E-1
 2 71
38 GO:0034769 basement membrane disassembly 1.718E-3 2.339E-2
1.603E-1
9.121E-1
 1 2
39 GO:1990268 response to gold nanoparticle 1.718E-3 2.339E-2
1.603E-1
9.121E-1
 1 2
40 GO:0007548 sex differentiation 2.158E-3 2.865E-2
1.963E-1
1.000E0
 3 309
41 GO:0036112 medium-chain fatty-acyl-CoA metabolic process 2.575E-3 2.973E-2
2.037E-1
1.000E0
 1 3
42 GO:0097195 pilomotor reflex 2.575E-3 2.973E-2
2.037E-1
1.000E0
 1 3
43 GO:0018171 peptidyl-cysteine oxidation 2.575E-3 2.973E-2
2.037E-1
1.000E0
 1 3
44 GO:2000611 positive regulation of thyroid hormone generation 2.575E-3 2.973E-2
2.037E-1
1.000E0
 1 3
45 GO:0019254 carnitine metabolic process, CoA-linked 2.575E-3 2.973E-2
2.037E-1
1.000E0
 1 3
46 GO:0042335 cuticle development 2.575E-3 2.973E-2
2.037E-1
1.000E0
 1 3
47 GO:0009062 fatty acid catabolic process 3.011E-3 3.375E-2
2.313E-1
1.000E0
 2 96
48 GO:0019395 fatty acid oxidation 3.198E-3 3.375E-2
2.313E-1
1.000E0
 2 99
49 GO:0034440 lipid oxidation 3.326E-3 3.375E-2
2.313E-1
1.000E0
 2 101
50 GO:0019079 viral genome replication 3.391E-3 3.375E-2
2.313E-1
1.000E0
 2 102
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 16 input genes in category / 47 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005782 peroxisomal matrix 6.299E-8 1.480E-6 6.570E-6 2.961E-6 4 48
2 GO:0031907 microbody lumen 6.299E-8 1.480E-6 6.570E-6 2.961E-6 4 48
3 GO:0044438 microbody part 1.050E-6 1.233E-5 5.474E-5 4.934E-5 4 96
4 GO:0044439 peroxisomal part 1.050E-6 1.233E-5 5.474E-5 4.934E-5 4 96
5 GO:0005777 peroxisome 5.012E-6 3.926E-5 1.742E-4 2.356E-4 4 142
6 GO:0042579 microbody 5.012E-6 3.926E-5 1.742E-4 2.356E-4 4 142
7 GO:0005759 mitochondrial matrix 3.585E-4 2.407E-3 1.068E-2 1.685E-2 4 425
8 GO:0005778 peroxisomal membrane 1.062E-3 5.548E-3 2.462E-2 4.994E-2 2 58
9 GO:0031903 microbody membrane 1.062E-3 5.548E-3 2.462E-2 4.994E-2 2 58
10 GO:0016324 apical plasma membrane 2.542E-3 1.195E-2
5.302E-2
1.195E-1
 3 335
11 GO:0045177 apical part of cell 5.064E-3 2.164E-2
9.603E-2
2.380E-1
 3 428
12 GO:0008385 IkappaB kinase complex 9.197E-3 3.602E-2
1.599E-1
4.323E-1
 1 11
13 GO:0043209 myelin sheath 1.216E-2 4.397E-2
1.951E-1
5.716E-1
 2 202
14 GO:0005766 primary lysosome 1.501E-2 4.703E-2
2.087E-1
7.054E-1
 1 18
15 GO:0042582 azurophil granule 1.501E-2 4.703E-2
2.087E-1
7.054E-1
 1 18
Show 10 more annotations

4: Human Phenotype [Display Chart] 7 input genes in category / 351 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 13 input genes in category / 408 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0003186 abnormal redox activity 1.056E-6 4.310E-4 2.840E-3 4.310E-4 5 163

6: Domain [Display Chart] 16 input genes in category / 139 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF10417 1-cysPrx C Pfam 5.105E-9 3.548E-7 1.957E-6 7.096E-7 3 5
2 IPR019479 Peroxiredoxin C InterPro 5.105E-9 3.548E-7 1.957E-6 7.096E-7 3 5
3 IPR000866 AhpC/TSA InterPro 1.785E-8 6.202E-7 3.421E-6 2.481E-6 3 7
4 PF00578 AhpC-TSA Pfam 1.785E-8 6.202E-7 3.421E-6 2.481E-6 3 7
5 3.40.30.10 - Gene3D 2.932E-6 8.151E-5 4.495E-4 4.075E-4 4 122
6 IPR012336 Thioredoxin-like fold InterPro 4.013E-6 9.296E-5 5.127E-4 5.578E-4 4 132
7 IPR013766 Thioredoxin domain InterPro 5.341E-6 1.061E-4 5.849E-4 7.424E-4 3 41
8 PS51352 THIOREDOXIN 2 PROSITE 6.177E-6 1.073E-4 5.919E-4 8.586E-4 3 43
9 1.10.640.10 - Gene3D 3.065E-5 3.277E-4 1.807E-3 4.260E-3 2 10
10 PS50292 PEROXIDASE 3 PROSITE 3.065E-5 3.277E-4 1.807E-3 4.260E-3 2 10
11 IPR019791 Haem peroxidase animal InterPro 3.065E-5 3.277E-4 1.807E-3 4.260E-3 2 10
12 IPR010255 Haem peroxidase InterPro 3.065E-5 3.277E-4 1.807E-3 4.260E-3 2 10
13 PF03098 An peroxidase Pfam 3.065E-5 3.277E-4 1.807E-3 4.260E-3 2 10
14 IPR020904 Sc DH/Rdtase CS InterPro 4.002E-4 3.124E-3 1.723E-2
5.563E-2
 2 35
15 PF06628 Catalase-rel Pfam 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
16 PD021735 Hepsin-SRCR ProDom 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
17 IPR024711 Catalase clade1/3 InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
18 PS00437 CATALASE 1 PROSITE 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
19 IPR024708 Catalase AS InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
20 IPR002226 Catalase haem BS InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
21 SM01060 Catalase SMART 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
22 IPR010582 Catalase immune responsive InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
23 IPR006322 Glutathione Rdtase euk/bac InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
24 IPR029609 MPO InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
25 PF01575 MaoC dehydratas Pfam 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
26 2.40.180.10 - Gene3D 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
27 PF09272 Hepsin-SRCR Pfam 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
28 IPR018028 Catalase InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
29 PS00438 CATALASE 2 PROSITE 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
30 PS51255 ADPK PROSITE 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
31 PF00199 Catalase Pfam 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
32 PS51402 CATALASE 3 PROSITE 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
33 PF04587 ADP PFK GK Pfam 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
34 IPR002539 MaoC dom InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
35 IPR011614 Catalase core InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
36 IPR015352 Hepsin-SRCR dom InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
37 IPR007666 ADP PFK/GK InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
38 IPR020835 Catalase-like dom InterPro 8.540E-4 3.124E-3 1.723E-2
1.187E-1
 1 1
39 PS00061 ADH SHORT PROSITE 9.186E-4 3.274E-3 1.806E-2
1.277E-1
 2 53
40 PF00106 adh short Pfam 9.890E-4 3.437E-3 1.895E-2
1.375E-1
 2 55
41 IPR002347 SDR fam InterPro 1.025E-3 3.475E-3 1.917E-2
1.425E-1
 2 56
42 IPR029595 DUOX1 InterPro 1.707E-3 5.651E-3 3.116E-2
2.373E-1
 1 2
43 IPR024706 Peroxiredoxin AhpC-typ InterPro 2.560E-3 8.275E-3 4.564E-2
3.558E-1
 1 3
44 IPR003033 SCP2 sterol-bd dom InterPro 4.263E-3 1.209E-2
6.670E-2
5.926E-1
 1 5
45 3.30.1050.10 - Gene3D 4.263E-3 1.209E-2
6.670E-2
5.926E-1
 1 5
46 PF02852 Pyr redox dim Pfam 4.263E-3 1.209E-2
6.670E-2
5.926E-1
 1 5
47 PS00076 PYRIDINE REDOX 1 PROSITE 4.263E-3 1.209E-2
6.670E-2
5.926E-1
 1 5
48 PF02036 SCP2 Pfam 4.263E-3 1.209E-2
6.670E-2
5.926E-1
 1 5
49 IPR012999 Pyr OxRdtase I AS InterPro 4.263E-3 1.209E-2
6.670E-2
5.926E-1
 1 5
50 IPR029056 Ribokinase-like InterPro 5.114E-3 1.316E-2
7.257E-2
7.108E-1
 1 6
Show 45 more annotations

7: Pathway [Display Chart] 16 input genes in category / 141 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1270420 Detoxification of Reactive Oxygen Species BioSystems: REACTOME 1.308E-7 1.844E-5 1.020E-4 1.844E-5 4 38
2 131226 Peroxisome BioSystems: KEGG 3.145E-6 2.217E-4 1.226E-3 4.434E-4 4 83
3 1270034 Beta-oxidation of very long chain fatty acids BioSystems: REACTOME 2.316E-5 8.163E-4 4.514E-3 3.265E-3 2 6
4 142227 glutathione redox reactions I BioSystems: BIOCYC 2.316E-5 8.163E-4 4.514E-3 3.265E-3 2 6
5 MAP00680 Methane metabolism MAP00680 Methane metabolism GenMAPP 3.240E-5 9.136E-4 5.052E-3 4.568E-3 2 7
6 1270033 Beta-oxidation of pristanoyl-CoA BioSystems: REACTOME 6.927E-5 1.628E-3 9.001E-3 9.766E-3 2 10
7 PW:0000016 amyotrophic lateral sclerosis disease Pathway Ontology 1.610E-4 3.243E-3 1.793E-2 2.270E-2 2 15
8 MAP00480 Glutathione metabolism MAP00480 Glutathione metabolism GenMAPP 3.524E-4 6.211E-3 3.434E-2 4.969E-2 2 22
9 1270031 Peroxisomal lipid metabolism BioSystems: REACTOME 6.161E-4 9.652E-3
5.337E-2
8.687E-2
 2 29
10 142224 glutathione redox reactions II BioSystems: BIOCYC 1.285E-3 1.647E-2
9.109E-2
1.812E-1
 1 1
11 PW:0000068 methane metabolic Pathway Ontology 1.285E-3 1.647E-2
9.109E-2
1.812E-1
 1 1
12 82973 Glutathione metabolism BioSystems: KEGG 2.131E-3 2.429E-2
1.343E-1
3.005E-1
 2 54
13 1270414 Cellular responses to stress BioSystems: REACTOME 2.239E-3 2.429E-2
1.343E-1
3.158E-1
 4 454
14 142308 ethanol degradation IV BioSystems: BIOCYC 5.131E-3 4.516E-2
2.497E-1
7.235E-1
 1 4
15 1339154 Metabolism of ingested H2SeO4 and H2SeO3 into H2Se BioSystems: REACTOME 5.131E-3 4.516E-2
2.497E-1
7.235E-1
 1 4
16 1269655 TP53 Regulates Metabolic Genes BioSystems: REACTOME 5.315E-3 4.516E-2
2.497E-1
7.494E-1
 2 86
17 545348 mitochondrial L-carnitine shuttle BioSystems: BIOCYC 6.410E-3 4.516E-2
2.497E-1
9.038E-1
 1 5
18 1383034 Signaling by MST1 BioSystems: REACTOME 6.410E-3 4.516E-2
2.497E-1
9.038E-1
 1 5
19 1270184 Sulfide oxidation to sulfate BioSystems: REACTOME 6.410E-3 4.516E-2
2.497E-1
9.038E-1
 1 5
20 1270133 Metabolism of nucleotides BioSystems: REACTOME 6.715E-3 4.516E-2
2.497E-1
9.468E-1
 2 97
21 1270091 Synthesis of 15-eicosatetraenoic acid derivatives BioSystems: REACTOME 7.688E-3 4.516E-2
2.497E-1
1.000E0
 1 6
22 545308 ceramide de novo biosynthesis BioSystems: BIOCYC 7.688E-3 4.516E-2
2.497E-1
1.000E0
 1 6
23 1270092 Synthesis of 12-eicosatetraenoic acid derivatives BioSystems: REACTOME 7.688E-3 4.516E-2
2.497E-1
1.000E0
 1 6
24 1457795 MET Receptor Activation BioSystems: REACTOME 7.688E-3 4.516E-2
2.497E-1
1.000E0
 1 6
25 SMP00054 Fatty Acid Elongation In Mitochondria SMPDB 8.964E-3 4.621E-2
2.555E-1
1.000E0
 1 7
26 814926 Carbon metabolism BioSystems: KEGG 9.172E-3 4.621E-2
2.555E-1
1.000E0
 2 114
27 SMP00052 Beta Oxidation of Very Long Chain Fatty Acids SMPDB 1.024E-2 4.621E-2
2.555E-1
1.000E0
 1 8
28 1270158 Metabolism of amino acids and derivatives BioSystems: REACTOME 1.069E-2 4.621E-2
2.555E-1
1.000E0
 3 367
29 1270090 Synthesis of 5-eicosatetraenoic acids BioSystems: REACTOME 1.151E-2 4.621E-2
2.555E-1
1.000E0
 1 9
30 1270183 Degradation of cysteine and homocysteine BioSystems: REACTOME 1.151E-2 4.621E-2
2.555E-1
1.000E0
 1 9
31 SMP00015 Glutathione Metabolism SMPDB 1.151E-2 4.621E-2
2.555E-1
1.000E0
 1 9
32 1269704 mRNA Editing: C to U Conversion BioSystems: REACTOME 1.151E-2 4.621E-2
2.555E-1
1.000E0
 1 9
33 1269705 Formation of the Editosome BioSystems: REACTOME 1.151E-2 4.621E-2
2.555E-1
1.000E0
 1 9
34 1270137 Purine catabolism BioSystems: REACTOME 1.278E-2 4.621E-2
2.555E-1
1.000E0
 1 10
35 1270177 Thyroxine biosynthesis BioSystems: REACTOME 1.278E-2 4.621E-2
2.555E-1
1.000E0
 1 10
36 M96 Free Radical Induced Apoptosis MSigDB C2 BIOCARTA (v6.0) 1.278E-2 4.621E-2
2.555E-1
1.000E0
 1 10
37 SMP00030 Oxidation of Branched Chain Fatty Acids SMPDB 1.278E-2 4.621E-2
2.555E-1
1.000E0
 1 10
38 1108784 reactive oxygen species degradation BioSystems: BIOCYC 1.278E-2 4.621E-2
2.555E-1
1.000E0
 1 10
39 83026 Sulfur metabolism BioSystems: KEGG 1.278E-2 4.621E-2
2.555E-1
1.000E0
 1 10
40 PW:0000134 glutathione metabolic Pathway Ontology 1.405E-2 4.717E-2
2.608E-1
1.000E0
 1 11
41 PW:0000040 androgen and estrogen metabolic Pathway Ontology 1.405E-2 4.717E-2
2.608E-1
1.000E0
 1 11
42 1269703 mRNA Editing BioSystems: REACTOME 1.405E-2 4.717E-2
2.608E-1
1.000E0
 1 11
43 524496 Ceramide biosynthesis BioSystems: KEGG 1.532E-2 4.909E-2
2.715E-1
1.000E0
 1 12
44 413432 Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate BioSystems: KEGG 1.532E-2 4.909E-2
2.715E-1
1.000E0
 1 12
Show 39 more annotations

8: Pubmed [Display Chart] 16 input genes in category / 2613 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 18977241 Oxidative stress, telomere length and biomarkers of physical aging in a cohort aged 79 years from the 1932 Scottish Mental Survey. Pubmed 2.359E-14 3.480E-11 2.939E-10 6.165E-11 7 117
2 17601350 A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition. Pubmed 2.664E-14 3.480E-11 2.939E-10 6.960E-11 7 119
3 14651853 Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Pubmed 9.948E-14 8.665E-11 7.318E-10 2.599E-10 9 494
4 25975898 Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. Pubmed 1.014E-11 6.626E-9 5.596E-8 2.650E-8 4 12
5 12080185 Nonredundant antioxidant defense by multiple two-cysteine peroxiredoxins in human prostate cancer cells. Pubmed 2.412E-10 9.004E-8 7.604E-7 6.302E-7 3 4
6 12059788 A method for detection of overoxidation of cysteines: peroxiredoxins are oxidized in vivo at the active-site cysteine during oxidative stress. Pubmed 2.412E-10 9.004E-8 7.604E-7 6.302E-7 3 4
7 10548725 Characterization of mouse peroxiredoxin I genomic DNA and its expression. Pubmed 2.412E-10 9.004E-8 7.604E-7 6.302E-7 3 4
8 27689697 Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury. Pubmed 2.939E-10 9.599E-8 8.107E-7 7.679E-7 5 91
9 10514471 Characterization of human and murine PMP20 peroxisomal proteins that exhibit antioxidant activity in vitro. Pubmed 2.109E-9 6.123E-7 5.171E-6 5.510E-6 3 7
10 15858817 Comparative proteomic analysis identifies protein disulfide isomerase and peroxiredoxin 1 as new players involved in embryonic interdigital cell death. Pubmed 5.059E-9 1.202E-6 1.015E-5 1.322E-5 3 9
11 27998725 cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium. Pubmed 5.059E-9 1.202E-6 1.015E-5 1.322E-5 3 9
12 16424062 Tagging single-nucleotide polymorphisms in antioxidant defense enzymes and susceptibility to breast cancer. Pubmed 7.225E-9 1.452E-6 1.226E-5 1.888E-5 3 10
13 16868544 Interactions between genes involved in the antioxidant defence system and breast cancer risk. Pubmed 7.225E-9 1.452E-6 1.226E-5 1.888E-5 3 10
14 17893145 Conformation-specific binding of alpha-synuclein to novel protein partners detected by phage display and NMR spectroscopy. Pubmed 9.243E-8 1.344E-5 1.135E-4 2.415E-4 3 22
15 17676665 Proteomic analysis of the cellular responses induced in uninfected immune cells by cell-expressed X4 HIV-1 envelope. Pubmed 1.214E-7 1.344E-5 1.135E-4 3.173E-4 3 24
16 20485444 Common polymorphisms in ITGA2, PON1 and THBS2 are associated with coronary atherosclerosis in a candidate gene association study of the Chinese Han population. Pubmed 1.380E-7 1.344E-5 1.135E-4 3.607E-4 4 115
17 20732340 Evaluation of the serum catalase and myeloperoxidase activities in chronic arsenic-exposed individuals and concomitant cytogenetic damage. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
18 21031435 Differential expression of peroxiredoxins in prostate cancer: consistent upregulation of PRDX3 and PRDX4. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
19 14580687 Susceptibility to arsenic-induced hyperkeratosis and oxidative stress genes myeloperoxidase and catalase. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
20 23190175 Presence of autoantibody against two placental proteins, peroxiredoxin 3 and peroxiredoxin 4, in sera of recurrent pregnancy loss patients. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
21 17549373 Association of polymorphisms in myeloperoxidase and catalase genes with precancerous changes in the gastric mucosa of patients at inner-city hospitals in New York. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
22 23737084 Expression of peroxiredoxins I and IV in multiple myeloma: association with immunoglobulin accumulation. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
23 23746122 Serum malondialdehyde levels, myeloperoxidase and catalase activities in patients with nephrotic syndrome. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
24 22465269 Serum myeloperoxidase activity and oxidative stress in patients with acute brucellosis. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
25 12838770 [The study of the antioxidant enzymes in erythrocytes in lung diseases]. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
26 19897513 Functional variants in the catalase and myeloperoxidase genes, ambient air pollution, and respiratory-related school absences: an example of epistasis in gene-environment interactions. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
27 9388242 Regulatory role for a novel human thioredoxin peroxidase in NF-kappaB activation. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
28 15978628 Antioxidant enzymes and lipid peroxides in children with cerebral palsy. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
29 12516882 Acute phase immune response to exercise coexists with decreased neutrophil antioxidant enzyme defences. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
30 21417634 Comparative proteomic analysis of cellular response of human airway epithelial cells (A549) to benzo(a)pyrene. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
31 20610706 Role of peroxiredoxin 1 and peroxiredoxin 4 in protection of respiratory syncytial virus-induced cysteinyl oxidation of nuclear cytoskeletal proteins. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
32 22424448 Peroxiredoxins 3 and 4 are overexpressed in prostate cancer tissue and affect the proliferation of prostate cancer cells in vitro. Pubmed 1.645E-7 1.344E-5 1.135E-4 4.299E-4 2 2
33 22002062 Two proteases, trypsin domain-containing 1 (Tysnd1) and peroxisomal lon protease (PsLon), cooperatively regulate fatty acid β-oxidation in peroxisomal matrix. Pubmed 1.963E-7 1.555E-5 1.313E-4 5.130E-4 3 28
34 10501973 Genetic mapping of six mouse peroxiredoxin genes and fourteen peroxiredoxin related sequences. Pubmed 3.266E-7 2.510E-5 2.120E-4 8.533E-4 3 33
35 15705913 Polymorphisms in genes related to oxidative stress (MPO, MnSOD, CAT) and survival after treatment for breast cancer. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
36 16385446 A testing framework for identifying susceptibility genes in the presence of epistasis. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
37 8360158 Cloning and characterization of a 23-kDa stress-induced mouse peritoneal macrophage protein. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
38 28397206 Relationship between maternal blood ceruloplasmin level, catalase and myeloperoxidase activity and neural tube defects. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
39 19731237 Myeloperoxidase and superoxide dismutase 2 polymorphisms comodulate the risk of hepatocellular carcinoma and death in alcoholic cirrhosis. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
40 15149466 Native specific activity of glutathione peroxidase (GPx-1), phospholipid hydroperoxide glutathione peroxidase (PHGPx) and glutathione reductase (GR) does not differ between normo- and hypomotile human sperm samples. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
41 22959522 The association between polymorphisms in prooxidant or antioxidant enzymes (myeloperoxidase, SOD2, and CAT) and genes and prostate cancer risk in the Chinese population of Han nationality. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
42 10632718 Polypeptides differentially expressed in imaginal discs define the peroxiredoxin family of genes in Drosophila. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
43 11771746 Protein levels of human peroxiredoxin subtypes in brains of patients with Alzheimer's disease and Down syndrome. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
44 27706591 Polymorphisms of eNOS, catalase, and myeloperoxidase genes in prostate cancer in Turkish men: preliminary results. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
45 8496166 A human cDNA corresponding to a gene overexpressed during cell proliferation encodes a product sharing homology with amoebic and bacterial proteins. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
46 19902075 Activity of antioxidant enzymes in the wound in patients with deep burns. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
47 18544346 Crucial role of peroxiredoxin III in placental antioxidant defense of mice. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
48 23773345 Manganese superoxide dismutase Ile58Thr, catalase C-262T and myeloperoxidase G-463A gene polymorphisms in patients with prostate cancer: relation to advanced and metastatic disease. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
49 11904290 Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site. Pubmed 4.935E-7 2.632E-5 2.223E-4 1.289E-3 2 3
50 20178365 A proteome-wide perspective on peroxisome targeting signal 1(PTS1)-Pex5p affinities. Pubmed 7.905E-7 4.131E-5 3.489E-4 2.066E-3 3 44
Show 45 more annotations

9: Interaction [Display Chart] 16 input genes in category / 475 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:PRDX2 PRDX2 interactions 9.071E-8 4.309E-5 2.905E-4 4.309E-5 5 133
2 int:PRDX1 PRDX1 interactions 8.548E-6 2.030E-3 1.369E-2 4.060E-3 4 151
3 int:CAT CAT interactions 1.631E-5 2.582E-3 1.741E-2 7.746E-3 3 56
4 int:PRDX4 PRDX4 interactions 2.801E-5 3.237E-3 2.182E-2 1.331E-2 3 67
5 int:SNCA SNCA interactions 3.690E-5 3.237E-3 2.182E-2 1.753E-2 4 219
6 int:PRDX3 PRDX3 interactions 4.770E-5 3.237E-3 2.182E-2 2.266E-2 3 80
7 int:SUMO4 SUMO4 interactions 4.770E-5 3.237E-3 2.182E-2 2.266E-2 3 80
8 int:PEX5 PEX5 interactions 8.480E-5 5.035E-3 3.394E-2 4.028E-2 3 97
9 int:SOD1 SOD1 interactions 1.937E-4 9.924E-3
6.691E-2
9.199E-2
 4 336
10 int:TANGO2 TANGO2 interactions 2.089E-4 9.924E-3
6.691E-2
9.924E-2
 2 24
11 int:ACAA1 ACAA1 interactions 3.978E-4 1.718E-2
1.158E-1
1.890E-1
 2 33
12 int:PTP4A2 PTP4A2 interactions 4.739E-4 1.876E-2
1.265E-1
2.251E-1
 2 36
13 int:SOD2 SOD2 interactions 7.745E-4 2.830E-2
1.908E-1
3.679E-1
 2 46
14 int:ENO3 ENO3 interactions 9.147E-4 3.104E-2
2.092E-1
4.345E-1
 2 50
15 int:HSD17B4 HSD17B4 interactions 1.146E-3 3.630E-2
2.447E-1
5.445E-1
 2 56
16 int:PEBP1 PEBP1 interactions 1.315E-3 3.903E-2
2.631E-1
6.245E-1
 2 60
17 int:PLPBP PLPBP interactions 1.403E-3 3.921E-2
2.643E-1
6.665E-1
 2 62
18 int:IDH1 IDH1 interactions 1.588E-3 4.191E-2
2.826E-1
7.544E-1
 2 66
19 int:GLTPD2 GLTPD2 interactions 1.807E-3 4.517E-2
3.045E-1
8.582E-1
 1 2
Show 14 more annotations

10: Cytoband [Display Chart] 16 input genes in category / 16 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 19q11-q13.2 19q11-q13.2 4.616E-4 7.386E-3 2.497E-2 7.386E-3 1 1
2 10q25-q26 10q25-q26 1.845E-3 1.476E-2 4.991E-2 2.952E-2 1 4
3 18q21.3 18q21.3 5.067E-3 2.022E-2
6.835E-2
8.107E-2
 1 11
4 5q21 5q21 5.526E-3 2.022E-2
6.835E-2
8.842E-2
 1 12
5 17q23.1 17q23.1 7.362E-3 2.022E-2
6.835E-2
1.178E-1
 1 16
6 9q34.1 9q34.1 8.737E-3 2.022E-2
6.835E-2
1.398E-1
 1 19
7 8p21.1 8p21.1 9.194E-3 2.022E-2
6.835E-2
1.471E-1
 1 20
8 Xp22.11 Xp22.11 1.011E-2 2.022E-2
6.835E-2
1.618E-1
 1 22
9 15q15.3 15q15.3 1.194E-2 2.122E-2
7.175E-2
1.910E-1
 1 26
10 19q13.31 19q13.31 1.422E-2 2.275E-2
7.690E-2
2.275E-1
 1 31
11 15q24.1 15q24.1 1.649E-2 2.399E-2
8.110E-2
2.639E-1
 1 36
12 1p34.1 1p34.1 2.600E-2 3.366E-2
1.138E-1
4.159E-1
 1 57
13 11p13 11p13 2.735E-2 3.366E-2
1.138E-1
4.375E-1
 1 60
14 11q13.1 11q13.1 3.049E-2 3.485E-2
1.178E-1
4.878E-1
 1 67
15 22q13.1 22q13.1 4.031E-2 4.300E-2
1.454E-1
6.450E-1
 1 89
Show 10 more annotations

11: Transcription Factor Binding Site [Display Chart] 13 input genes in category / 79 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 10 input genes in category / 7 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 953 Peroxiredoxins genenames.org 2.389E-9 1.673E-8 4.337E-8 1.673E-8 3 6
2 743 Short chain dehydrogenase/reductase superfamily genenames.org 7.583E-4 2.654E-3 6.881E-3 5.308E-3 2 76
3 406 Apolipoprotein B mRNA editing enzyme catalytic subunits genenames.org 6.578E-3 1.535E-2 3.979E-2 4.604E-2 1 12
4 890 Selenoproteins genenames.org 1.366E-2 2.390E-2
6.198E-2
9.562E-2
 1 25
5 738 Proteases, serine genenames.org 3.410E-2 4.774E-2
1.238E-1
2.387E-1
 1 63

13: Coexpression [Display Chart] 16 input genes in category / 1808 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M6891 Genes known to modulate ROS or whose expression changes in response to ROS MSigDB C2: CGP Curated Gene Sets (v6.0) 7.244E-14 1.310E-10 1.058E-9 1.310E-10 6 36
2 M5938 Genes up-regulated by reactive oxigen species (ROS). MSigDB H: Hallmark Gene Sets (v6.0) 5.176E-13 4.679E-10 3.780E-9 9.358E-10 6 49
3 M5949 Genes encoding components of peroxisome. MSigDB H: Hallmark Gene Sets (v6.0) 6.725E-7 4.053E-4 3.274E-3 1.216E-3 4 104
4 19808960-Table2 Human Kidney Moore09 38genes GeneSigDB 1.602E-6 7.243E-4 5.851E-3 2.897E-3 3 34
5 M9433 Mitochondrial genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.901E-6 1.937E-3 1.565E-2 1.428E-2 5 429
6 M7683 Genes down-regulated in ankle joints: SPHK1 [GeneID=8877] versus wildtype over-expressing TNF [GeneID=7124]. MSigDB C7: Immunologic Signatures (v6.0) 8.912E-6 1.937E-3 1.565E-2 1.611E-2 4 199
7 M5905 Genes up-regulated during adipocyte differentiation (adipogenesis). MSigDB H: Hallmark Gene Sets (v6.0) 9.090E-6 1.937E-3 1.565E-2 1.644E-2 4 200
8 M2999 Reactive oxidative species (ROS) genes; based on literature and sequence annotation resources and converted to Affymetrix HG-U133A probe sets. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.396E-6 1.937E-3 1.565E-2 1.699E-2 2 7
9 M9577 Mitochondrial genes MSigDB C2: CGP Curated Gene Sets (v6.0) 9.643E-6 1.937E-3 1.565E-2 1.743E-2 5 447
10 20460173-ImmPortAntimicrobials Human Immune Kong10 544genes ImmPort Antimicrobials GeneSigDB 1.217E-5 2.058E-3 1.663E-2 2.200E-2 5 469
11 19286929-SuppTable2b Mouse Lung Rangasamy09 10genes DownRegulatedPhaseIIGenes GeneSigDB 1.252E-5 2.058E-3 1.663E-2 2.264E-2 2 8
12 M13283 Liver selective genes MSigDB C2: CGP Curated Gene Sets (v6.0) 1.988E-5 2.925E-3 2.363E-2 3.594E-2 4 244
13 M9911 Genes negatively correlated with recurrence free survival in patients with hepatitis B-related (HBV) hepatocellular carcinoma (HCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.158E-5 2.925E-3 2.363E-2 3.902E-2 3 80
14 16536878-SuppTable1 Human Breast Muggerud06 271genes GeneSigDB 2.291E-5 2.925E-3 2.363E-2 4.143E-2 4 253
15 15897907-SuppTable5 Human Breast Farmer05 269genes basal apocrine luminal GeneSigDB 2.474E-5 2.925E-3 2.363E-2 4.473E-2 4 258
16 18381418-Table1 Mouse Prostate Ouyang08 121genes GeneSigDB 2.589E-5 2.925E-3 2.363E-2 4.680E-2 3 85
17 M2662 Selected electrophile and drug detoxication genes down-regulated in A549 and H460 cells (lung cancer) upon knockdown of NFE2L2 [GeneID=4780] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.683E-5 4.981E-3 4.023E-2
8.467E-2
 2 15
18 19520915-Table1 Mouse Lung not cancer Blake10 19genes GeneSigDB 6.816E-5 6.846E-3
5.530E-2
1.232E-1
 2 18
19 M18954 Genes up-regulated in HCT116 cells (colon cancer) after treatment with amifostine [PubChem=2141] depending on the presence of TP53 [GeneID=7157]: TP53-positive vs TP53-null cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.457E-5 8.047E-3
6.500E-2
1.529E-1
 2 20
20 M1859 Genes down-regulated in ALL (acute lymphoblastic leukemia) blasts after 1 week of treatment with glucocorticoids. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.243E-5 8.356E-3
6.749E-2
1.671E-1
 4 362
21 M10633 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.220E-4 1.051E-2
8.487E-2
2.207E-1
 3 143
22 17009876-tableS3b Mouse StemCell Ramos06 211genes GeneSigDB 1.701E-4 1.186E-2
9.578E-2
3.076E-1
 3 160
23 18441282-Table2 Mouse Lung not cancer Adair-Kirk08 35genes GeneSigDB 1.801E-4 1.186E-2
9.578E-2
3.255E-1
 2 29
24 M1997 Genes distinctly down-regulated in primary fibroblast cultures from Werner syndrom patients compared to those from normal young donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.801E-4 1.186E-2
9.578E-2
3.255E-1
 2 29
25 M8949 Genes up-regulated in T conv cells from aged PPARG [GeneID=5468] knockout: visceral adipose tissue versus lymph node. MSigDB C7: Immunologic Signatures (v6.0) 1.830E-4 1.186E-2
9.578E-2
3.308E-1
 3 164
26 M1995 Genes distinctly down-regulated in primary fibroblast cultures from normal old donors compared to those from normal young donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.928E-4 1.186E-2
9.578E-2
3.487E-1
 2 30
27 19204204-SupplementaryTable3 Human Breast Parker09 498genes IntrinsicGenes Perreard2006 GeneSigDB 2.010E-4 1.186E-2
9.578E-2
3.634E-1
 4 443
28 19204204-SupplementaryTable6 Human Breast Parker09 501genes IntrinsicGenes Sorlie2003 GeneSigDB 2.010E-4 1.186E-2
9.578E-2
3.634E-1
 4 443
29 M13713 Genes co-regulated in uterus during a time course response to progesterone [PubChem=5994]: SOM cluster 13. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.105E-4 1.186E-2
9.578E-2
3.807E-1
 3 172
30 M8667 Genes down-regulated in monocytes (6h): untreated versus M. tuberculosis 19 kDa lipopeptide. MSigDB C7: Immunologic Signatures (v6.0) 2.142E-4 1.186E-2
9.578E-2
3.872E-1
 3 173
31 16536878-SuppTable2 Human Breast Muggerud06 232genes GeneSigDB 2.178E-4 1.186E-2
9.578E-2
3.938E-1
 3 174
32 15375163-SuppTable2 Mouse Liver Anderson04 41genes GeneSigDB 2.197E-4 1.186E-2
9.578E-2
3.972E-1
 2 32
33 12829800-IntrinsicList Human Breast Sorlie03 552genes IntrinsicGeneList GeneSigDB 2.227E-4 1.186E-2
9.578E-2
4.026E-1
 4 455
34 19204204-SupplementaryTable9 Human Breast Parker09 500genes IntrinsicGenes SorlieAnnot GeneSigDB 2.264E-4 1.186E-2
9.578E-2
4.094E-1
 4 457
35 M5792 Genes with increased copy number that correlates with increased expression across six different lung adenocarcinoma cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.329E-4 1.186E-2
9.578E-2
4.211E-1
 3 178
36 M8467 Genes up-regulated in peripheral blood mononuclear cells (PBMC) from sickle cell disease patients compared to those from healthy subjects. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.446E-4 1.186E-2
9.578E-2
4.423E-1
 3 181
37 M1678 Strongly up-regulated at 96 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.778E-4 1.186E-2
9.578E-2
5.022E-1
 3 189
38 M3183 Genes down-regulated in comparison of IgD+ B cells versus IgD- B cells. MSigDB C7: Immunologic Signatures (v6.0) 3.137E-4 1.186E-2
9.578E-2
5.672E-1
 3 197
39 M8299 Genes down-regulated in thymocytes: double positive versus CD4 [GeneID=920] single positive. MSigDB C7: Immunologic Signatures (v6.0) 3.231E-4 1.186E-2
9.578E-2
5.843E-1
 3 199
40 M4927 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee before vaccination versus that after the vaccination. MSigDB C7: Immunologic Signatures (v6.0) 3.231E-4 1.186E-2
9.578E-2
5.843E-1
 3 199
41 M5173 Genes down-regulated in comparison of dendritic cells (DC) versus untreated macrophages. MSigDB C7: Immunologic Signatures (v6.0) 3.231E-4 1.186E-2
9.578E-2
5.843E-1
 3 199
42 M4243 Genes down-regulated in comparison of untreated CD4 [GeneID=920] T cells at 2 h versus the untreated cells at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 3.231E-4 1.186E-2
9.578E-2
5.843E-1
 3 199
43 M6626 Genes down-regulated in bone marrow-derived macrophages with IL6 [GeneID=3469] knockout and 45 min of stimulation by AIL10 [GeneID=3486] and LPS versus IL6 [GeneID=3469] and LPS. MSigDB C7: Immunologic Signatures (v6.0) 3.231E-4 1.186E-2
9.578E-2
5.843E-1
 3 199
44 M3262 Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) cultured for 0 h versus PBMC cultured for 12 h with YF17D vaccine. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
45 M8568 Genes down-regulated in Th1 cells 5 days post polarization: control versus stimulated with anti-CD3 and anti-CD28. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
46 M7270 Genes up-regulated in double positive thymocytes: TCF12 [GeneID=6939] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
47 M3597 Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 48 h. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
48 M4119 Genes up-regulated in comparison of dendritic cells (DC) stimulated with CpG DNA (TLR9 agonist) at 0.5 h versus those stimulated with CpG DNA (TLR9 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
49 M4808 Genes up-regulated in comparison of B cells versus NKT cells. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
50 M7953 Genes down-regulated in bone marrow-derived macrophages: wildtype versus PPARG [GeneID=5468] knockout. MSigDB C7: Immunologic Signatures (v6.0) 3.279E-4 1.186E-2
9.578E-2
5.929E-1
 3 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 16 input genes in category / 1223 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Human Cell Atlas Human Cell Atlas Erythro Erythro Subtype Early-Erythroblast Top 200 Genes Human Cell Atlas Human Cell Atlas Erythro Erythro Subtype Early-Erythroblast Top 200 Genes 4.830E-5 1.522E-2
1.170E-1
5.908E-2
 4 289
2 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ MultiLin Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ MultiLin Top 200 Genes 5.659E-5 1.522E-2
1.170E-1
6.921E-2
 4 301
3 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Subtype progenitor Ileum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Subtype progenitor Ileum Top 200 Genes Mouse Cell Atlas 5.881E-5 1.522E-2
1.170E-1
7.193E-2
 4 304
4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal VHL RCC Junk/Kidney Normal VHL RCC IF4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal VHL RCC Junk/Kidney Normal VHL RCC IF4 Adult, Development, and Cancer types 5.952E-5 1.522E-2
1.170E-1
7.280E-2
 3 106
5 Human Cell Atlas Human Cell Atlas Megakaryocytic Megakaryocytic Subtype CD34+ MKP Top 200 Genes Human Cell Atlas Human Cell Atlas Megakaryocytic Megakaryocytic Subtype CD34+ MKP Top 200 Genes 6.425E-5 1.522E-2
1.170E-1
7.857E-2
 4 311
6 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Subtype progenitor Duodenum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Subtype progenitor Duodenum Top 200 Genes Mouse Cell Atlas 8.471E-5 1.522E-2
1.170E-1
1.036E-1
 4 334
7 Mouse Cell Atlas Mouse Regional GI Enterocytes Transit amplifying Enterocyte progenitor Transit amplifying Enterocyte progenitor Subtype transit amplifying progenitor Ileum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Transit amplifying Enterocyte progenitor Transit amplifying Enterocyte progenitor Subtype transit amplifying progenitor Ileum Top 200 Genes Mouse Cell Atlas 8.770E-5 1.522E-2
1.170E-1
1.073E-1
 4 337
8 Human Cell Atlas Human Cell Atlas Erythro Erythro Subtype CD34+ MEP Top 200 Genes Human Cell Atlas Human Cell Atlas Erythro Erythro Subtype CD34+ MEP Top 200 Genes 1.038E-4 1.522E-2
1.170E-1
1.269E-1
 4 352
9 Human Cell Atlas Human Cell Atlas Megakaryocytic Megakaryocytic Top 200 Human Cell Atlas Human Cell Atlas Megakaryocytic Megakaryocytic Top 200 1.831E-4 1.522E-2
1.170E-1
2.240E-1
 4 408
10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell 2/Kidney Normal Wilms NK cell 2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell 2/Kidney Normal Wilms NK cell 2 Adult, Development, and Cancer types 2.131E-4 1.522E-2
1.170E-1
2.606E-1
 3 163
11 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney CD8 T cell/Kidney Normal-Cortex Wilms CD8 T cell/Kidney Normal-Cortex Wilms IT3 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney CD8 T cell/Kidney Normal-Cortex Wilms CD8 T cell/Kidney Normal-Cortex Wilms IT3 Adult, Development, and Cancer types 2.624E-4 1.522E-2
1.170E-1
3.210E-1
 2 33
12 Kidney10XCellRanger Six2TGC P0 UB UB Overall Top 200 Genes Kidney10XCellRanger Six2TGC P0 UB UB Overall Top 200 Genes 2.627E-4 1.522E-2
1.170E-1
3.212E-1
 3 175
13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Medulla post-natal kidney U U/Kidney Normal-Medulla post-natal kidney U12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Normal-Medulla post-natal kidney U U/Kidney Normal-Medulla post-natal kidney U12 Adult, Development, and Cancer types 2.627E-4 1.522E-2
1.170E-1
3.212E-1
 3 175
14 Kidney10XCellRanger Six2TGC P0 UB UB Top 200 Kidney10XCellRanger Six2TGC P0 UB UB Top 200 2.627E-4 1.522E-2
1.170E-1
3.212E-1
 3 175
15 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/monocyte Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/monocyte Tabula Muris Consortium 2.761E-4 1.522E-2
1.170E-1
3.377E-1
 3 178
16 Kidney10XCellRanger Six2TGC E14 UB UB Overall Top 200 Genes Kidney10XCellRanger Six2TGC E14 UB UB Overall Top 200 Genes 2.807E-4 1.522E-2
1.170E-1
3.433E-1
 3 179
17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal Wilms Nephron epithelium/Kidney Normal Wilms N12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal Wilms Nephron epithelium/Kidney Normal Wilms N12 Adult, Development, and Cancer types 2.947E-4 1.522E-2
1.170E-1
3.604E-1
 3 182
18 Kidney10XCellRanger Six2TGC E14 UB UB Subtype E14-Six2TGC-UB-C7-KC6 Top 200 Genes Kidney10XCellRanger Six2TGC E14 UB UB Subtype E14-Six2TGC-UB-C7-KC6 Top 200 Genes 3.043E-4 1.522E-2
1.170E-1
3.722E-1
 3 184
19 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter Normal cell/Ureter Normal RCC Normal cell/Ureter Normal RCC T8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter Normal cell/Ureter Normal RCC Normal cell/Ureter Normal RCC T8 Adult, Development, and Cancer types 3.092E-4 1.522E-2
1.170E-1
3.782E-1
 3 185
20 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Tumour Wilms Nephron epithelium/Kidney Tumour Wilms N16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Tumour Wilms Nephron epithelium/Kidney Tumour Wilms N16 Adult, Development, and Cancer types 3.141E-4 1.522E-2
1.170E-1
3.842E-1
 3 186
21 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Overall Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Overall Top 200 Genes Mouse Cell Atlas 3.241E-4 1.522E-2
1.170E-1
3.964E-1
 3 188
22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Tumour PapRCC IF-U/Kidney Tumour PapRCC IF15 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Tumour PapRCC IF-U/Kidney Tumour PapRCC IF15 Adult, Development, and Cancer types 3.241E-4 1.522E-2
1.170E-1
3.964E-1
 3 188
23 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/granulocytopoietic cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/granulocytopoietic cell Tabula Muris Consortium 3.241E-4 1.522E-2
1.170E-1
3.964E-1
 3 188
24 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Top 200 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Top 200 Mouse Cell Atlas 3.247E-4 1.522E-2
1.170E-1
3.971E-1
 4 474
25 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal-Cortex post-natal kidney Fetus other/Kidney Normal-Cortex post-natal kidney F12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal-Cortex post-natal kidney Fetus other/Kidney Normal-Cortex post-natal kidney F12 Adult, Development, and Cancer types 3.292E-4 1.522E-2
1.170E-1
4.026E-1
 3 189
26 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Erythroblast/Kidney Normal-Cortex Wilms Erythroblast Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Erythroblast/Kidney Normal-Cortex Wilms Erythroblast Adult, Development, and Cancer types 3.395E-4 1.522E-2
1.170E-1
4.153E-1
 3 191
27 Human Cell Atlas Human Cell Atlas HSC HSC Overall Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Overall Top 200 Genes 3.448E-4 1.522E-2
1.170E-1
4.217E-1
 3 192
28 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal-Medulla post-natal kidney Fetus other/Kidney Normal-Medulla post-natal kidney F13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal-Medulla post-natal kidney Fetus other/Kidney Normal-Medulla post-natal kidney F13 Adult, Development, and Cancer types 3.608E-4 1.522E-2
1.170E-1
4.413E-1
 3 195
29 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Normal cell/Kidney Normal-Cortex post-natal kidney Normal cell/Kidney Normal-Cortex post-natal kidney T14 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Normal cell/Kidney Normal-Cortex post-natal kidney Normal cell/Kidney Normal-Cortex post-natal kidney T14 Adult, Development, and Cancer types 3.608E-4 1.522E-2
1.170E-1
4.413E-1
 3 195
30 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Normal-Cortex Wilms IF-U Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Normal-Cortex Wilms IF-U Adult, Development, and Cancer types 4.263E-4 1.682E-2
1.293E-1
5.214E-1
 2 42
31 PP RBC 500 K4 PP RBC top-relative-expression-ranked 500 k-means-cluster#4 PCBC 4.263E-4 1.682E-2
1.293E-1
5.214E-1
 2 42
32 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour PapRCC U U/Kidney Tumour PapRCC U15 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour PapRCC U U/Kidney Tumour PapRCC U15 Adult, Development, and Cancer types 4.469E-4 1.708E-2
1.313E-1
5.466E-1
 2 43
33 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Normal VHL RCC EN-A/Kidney Normal VHL RCC EN4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-A/Kidney Normal VHL RCC EN-A/Kidney Normal VHL RCC EN4 Adult, Development, and Cancer types 7.049E-4 2.555E-2
1.964E-1
8.621E-1
 2 54
34 Kidney10XCellRanger Six2TGC E14 UB UB Subtype E14-Six2TGC-UB-C7-KC8 Top 200 Genes Kidney10XCellRanger Six2TGC E14 UB UB Subtype E14-Six2TGC-UB-C7-KC8 Top 200 Genes 7.103E-4 2.555E-2
1.964E-1
8.687E-1
 3 246
35 Kidney10XCellRanger Six2TGC E14 UB UB Top 200 Kidney10XCellRanger Six2TGC E14 UB UB Top 200 7.530E-4 2.631E-2
2.023E-1
9.209E-1
 3 251
36 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D PND07-28 Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D PND07-28 Top 200 Genes 9.808E-4 3.242E-2
2.492E-1
1.000E0
 3 275
37 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-D Top 200 Genes 9.808E-4 3.242E-2
2.492E-1
1.000E0
 3 275
38 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Ileum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte Enterocyte Subtype Enterocyte Ileum Top 200 Genes Mouse Cell Atlas 1.055E-3 3.394E-2
2.609E-1
1.000E0
 3 282
39 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephron epithelium/Kidney Normal-Cortex Wilms Nephron epithelium Adult, Development, and Cancer types 1.083E-3 3.397E-2
2.611E-1
1.000E0
 2 67
40 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC Top 200 Genes 1.178E-3 3.600E-2
2.767E-1
1.000E0
 3 293
41 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC-cycle Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC-cycle Top 200 Genes 1.224E-3 3.652E-2
2.807E-1
1.000E0
 3 297
42 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney CD8 T cell/Kidney Normal-Cortex Wilms CD8 T cell Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney CD8 T cell/Kidney Normal-Cortex Wilms CD8 T cell Adult, Development, and Cancer types 1.284E-3 3.689E-2
2.835E-1
1.000E0
 2 73
43 Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Subtype progenitor Jejunum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Enterocyte progenitor Enterocyte progenitor Subtype progenitor Jejunum Top 200 Genes Mouse Cell Atlas 1.297E-3 3.689E-2
2.835E-1
1.000E0
 3 303
44 GSM791114 100 Stem Cells, SC.CDP.BM, Sca1- Flt3+ MCSFR+ cKitlo, Bone marrow, avg-3 Immgen.org, GSE15907 1.617E-3 4.243E-2
3.262E-1
1.000E0
 2 82
45 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-D/Kidney Normal Wilms EN-D Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-D/Kidney Normal Wilms EN-D Adult, Development, and Cancer types 1.617E-3 4.243E-2
3.262E-1
1.000E0
 2 82
46 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ LMPP Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ LMPP Top 200 Genes 1.628E-3 4.243E-2
3.262E-1
1.000E0
 3 328
47 Mouse Cell Atlas Mouse Regional GI Enterocytes Transit amplifying Enterocyte progenitor Transit amplifying Enterocyte progenitor Subtype transit amplifying progenitor Duodenum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Transit amplifying Enterocyte progenitor Transit amplifying Enterocyte progenitor Subtype transit amplifying progenitor Duodenum Top 200 Genes Mouse Cell Atlas 1.671E-3 4.243E-2
3.262E-1
1.000E0
 3 331
48 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal-Cortex Wilms Junk/Kidney Normal-Cortex Wilms IN3 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Junk/Kidney Normal-Cortex Wilms Junk/Kidney Normal-Cortex Wilms IN3 Adult, Development, and Cancer types 1.695E-3 4.243E-2
3.262E-1
1.000E0
 2 84
49 Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-A Top 200 Genes Mouse Lung Development Lungmap Mouse Fluidigm Myeloid Subtype macrophage-A Top 200 Genes 1.700E-3 4.243E-2
3.262E-1
1.000E0
 3 333
50 Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Duodenum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Tuft Tuft Subtype Tuft Duodenum Top 200 Genes Mouse Cell Atlas 1.897E-3 4.572E-2
3.514E-1
1.000E0
 3 346
Show 45 more annotations

15: Computational [Display Chart] 13 input genes in category / 80 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M10134 MODULE 93 Oxidoreductases. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.056E-8 4.045E-6 2.008E-5 4.045E-6 6 182
2 M5428 MODULE 530 ROS (glutathione, ox stress). MSigDb: C4 - CM: Cancer Modules (v6.0) 9.415E-7 3.766E-5 1.870E-4 7.532E-5 3 16
3 M2027 MODULE 212 Catalytic activities / metabolism. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.409E-4 1.709E-2
8.486E-2
5.127E-2
 4 329

16: MicroRNA [Display Chart] 16 input genes in category / 353 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-769-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.708E-5 6.028E-3 3.885E-2 6.028E-3 3 229
2 hsa-miR-23b-3p:Functional MTI Functional MTI miRTarbase 4.706E-5 8.306E-3
5.353E-2
 1.661E-2 3 322
3 hsa-miR-6789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.070E-4 1.259E-2
8.112E-2
 3.776E-2 2 69
4 hsa-miR-375:Functional MTI Functional MTI miRTarbase 1.503E-4 1.326E-2
8.547E-2
5.305E-2
 3 477
5 hsa-miR-23a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.381E-4 2.776E-2
1.789E-1
1.900E-1
 2 155
6 hsa-miR-23b-5p:Functional MTI Functional MTI miRTarbase 5.381E-4 2.776E-2
1.789E-1
1.900E-1
 2 155
7 hsa-miR-4692:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.925E-4 2.776E-2
1.789E-1
2.444E-1
 2 176
8 hsa-miR-4514:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.082E-4 2.776E-2
1.789E-1
2.500E-1
 2 178
9 hsa-miR-8063:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.658E-4 2.776E-2
1.789E-1
3.056E-1
 2 197
10 hsa-miR-4698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.039E-3 2.776E-2
1.789E-1
3.667E-1
 2 216
11 hsa-miR-6783-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.106E-3 2.776E-2
1.789E-1
3.905E-1
 2 223
12 hsa-miR-1343-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.106E-3 2.776E-2
1.789E-1
3.905E-1
 2 223
13 hsa-miR-6852-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.156E-3 2.776E-2
1.789E-1
4.080E-1
 2 228
14 hsa-miR-607:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.186E-3 2.776E-2
1.789E-1
4.187E-1
 2 231
15 hsa-miR-6814-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.549E-3 2.776E-2
1.789E-1
5.469E-1
 1 7
16 hsa-miR-548am-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.869E-3 2.776E-2
1.789E-1
6.599E-1
 2 291
17 hsa-miR-548ah-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.869E-3 2.776E-2
1.789E-1
6.599E-1
 2 291
18 hsa-miR-548j-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.882E-3 2.776E-2
1.789E-1
6.644E-1
 2 292
19 hsa-miR-548aj-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.895E-3 2.776E-2
1.789E-1
6.689E-1
 2 293
20 hsa-miR-548x-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.895E-3 2.776E-2
1.789E-1
6.689E-1
 2 293
21 hsa-miR-548aq-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.895E-3 2.776E-2
1.789E-1
6.689E-1
 2 293
22 hsa-miR-548ae-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.895E-3 2.776E-2
1.789E-1
6.689E-1
 2 293
23 hsa-miR-6872-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.992E-3 2.776E-2
1.789E-1
7.031E-1
 1 9
24 hsa-miR-5096:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.011E-3 2.776E-2
1.789E-1
7.098E-1
 2 302
25 hsa-miR-6742-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.050E-3 2.776E-2
1.789E-1
7.237E-1
 2 305
26 hsa-miR-3181:mirSVR lowEffct hsa-miR-3181:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.144E-3 2.776E-2
1.789E-1
7.567E-1
 2 312
27 hsa-miR-214:PITA hsa-miR-214:PITA TOP PITA 2.239E-3 2.776E-2
1.789E-1
7.904E-1
 2 319
28 hsa-miR-6791-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.281E-3 2.776E-2
1.789E-1
8.050E-1
 2 322
29 hsa-miR-6829-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.281E-3 2.776E-2
1.789E-1
8.050E-1
 2 322
30 hsa-miR-10a*:mirSVR highEffct hsa-miR-10a*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.422E-3 2.849E-2
1.836E-1
8.548E-1
 2 332
31 hsa-miR-3163:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.566E-3 2.922E-2
1.884E-1
9.060E-1
 2 342
32 hsa-miR-181b-5p:Functional MTI Functional MTI miRTarbase 3.073E-3 3.275E-2
2.110E-1
1.000E0
 2 375
33 hsa-miR-660-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.089E-3 3.275E-2
2.110E-1
1.000E0
 2 376
34 hsa-miR-127-3p:mirSVR lowEffct hsa-miR-127-3p:mirSVR conserved lowEffect-0.1-0.5 MicroRNA.org 3.154E-3 3.275E-2
2.110E-1
1.000E0
 2 380
35 hsa-miR-3912-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.317E-3 3.346E-2
2.156E-1
1.000E0
 1 15
36 hsa-miR-3612:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.905E-3 3.770E-2
2.430E-1
1.000E0
 2 424
37 hsa-miR-650:Functional MTI Functional MTI miRTarbase 3.959E-3 3.770E-2
2.430E-1
1.000E0
 2 427
38 hsa-miR-939-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.179E-3 3.770E-2
2.430E-1
1.000E0
 2 439
39 hsa-miR-609:mirSVR highEffct hsa-miR-609:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.235E-3 3.770E-2
2.430E-1
1.000E0
 2 442
40 hsa-miR-668:mirSVR highEffct hsa-miR-668:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.272E-3 3.770E-2
2.430E-1
1.000E0
 2 444
41 hsa-miR-26a-5p:Functional MTI Functional MTI miRTarbase 4.519E-3 3.837E-2
2.473E-1
1.000E0
 2 457
42 hsa-miR-4722-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.635E-3 3.837E-2
2.473E-1
1.000E0
 2 463
43 hsa-miR-6727-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.674E-3 3.837E-2
2.473E-1
1.000E0
 2 465
44 hsa-miR-3141:mirSVR lowEffct hsa-miR-3141:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.991E-3 3.900E-2
2.513E-1
1.000E0
 2 481
45 hsa-miR-181c*:mirSVR lowEffct hsa-miR-181c*:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 5.031E-3 3.900E-2
2.513E-1
1.000E0
 2 483
46 hsa-miR-4279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.235E-3 3.900E-2
2.513E-1
1.000E0
 2 493
47 hsa-miR-523:mirSVR highEffct hsa-miR-523:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.303E-3 3.900E-2
2.513E-1
1.000E0
 1 24
48 hsa-miR-3621:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.303E-3 3.900E-2
2.513E-1
1.000E0
 1 24
49 hsa-miR-127-3p:Functional MTI Functional MTI miRTarbase 6.404E-3 4.614E-2
2.974E-1
1.000E0
 1 29
Show 44 more annotations

17: Drug [Display Chart] 16 input genes in category / 7530 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 ctd:C007164 cumene hydroperoxide CTD 2.151E-10 1.365E-6 1.297E-5 1.620E-6 5 52
2 ctd:D012460 Sulfasalazine CTD 3.624E-10 1.365E-6 1.297E-5 2.729E-6 6 140
3 CID000014801 MnO2 Stitch 7.824E-10 1.523E-6 1.447E-5 5.892E-6 6 159
4 ctd:D004178 Diquat CTD 9.432E-10 1.523E-6 1.447E-5 7.102E-6 6 164
5 ctd:C539612 2-acetylamino-3-(4-(2-acetylamino-2-carboxyethylsulfanylthiocarbonylamino)phenylthiocarbamoylsulfanyl)propionic acid CTD 1.128E-9 1.523E-6 1.447E-5 8.490E-6 3 4
6 CID000006009 aminopyrine Stitch 1.213E-9 1.523E-6 1.447E-5 9.137E-6 6 171
7 CID005358946 NSC291853 Stitch 2.818E-9 2.676E-6 2.544E-5 2.122E-5 3 5
8 CID000104913 DCFH-DA Stitch 2.843E-9 2.676E-6 2.544E-5 2.141E-5 5 86
9 CID000122831 Ac-623 Stitch 5.633E-9 4.034E-6 3.834E-5 4.242E-5 3 6
10 CID000010334 Dithiol Stitch 6.112E-9 4.034E-6 3.834E-5 4.603E-5 5 100
11 ctd:D011729 Pyridostigmine Bromide CTD 6.428E-9 4.034E-6 3.834E-5 4.840E-5 5 101
12 CID000006629 cumene hydroperoxide Stitch 6.428E-9 4.034E-6 3.834E-5 4.840E-5 5 101
13 ctd:C031618 sodium nitrate CTD 1.168E-8 6.766E-6 6.430E-5 8.796E-5 4 38
14 CID000001983 acetaminophen Stitch 1.872E-8 9.850E-6 9.361E-5 1.409E-4 6 270
15 CID001349907 methimazole Stitch 1.962E-8 9.850E-6 9.361E-5 1.478E-4 5 126
16 CID000000977 oxygen Stitch 2.197E-8 9.982E-6 9.487E-5 1.654E-4 7 499
17 CID000073318 8-OHdG Stitch 2.296E-8 9.982E-6 9.487E-5 1.729E-4 5 130
18 CID000003194 ebselen Stitch 2.386E-8 9.982E-6 9.487E-5 1.797E-4 5 131
19 ctd:C017160 cypermethrin CTD 2.691E-8 1.067E-5 1.014E-4 2.027E-4 6 287
20 ctd:C024070 pycnogenols CTD 4.637E-8 1.746E-5 1.659E-4 3.492E-4 3 11
21 CID000002973 deferoxamine Stitch 7.744E-8 2.629E-5 2.499E-4 5.831E-4 6 343
22 ctd:C032742 triclopyr CTD 8.031E-8 2.629E-5 2.499E-4 6.047E-4 3 13
23 ctd:D010846 Picloram CTD 8.031E-8 2.629E-5 2.499E-4 6.047E-4 3 13
24 ctd:C506540 arginyl-2,'6'-dimethyltyrosyl-lysyl-phenylalaninamide CTD 1.022E-7 3.206E-5 3.046E-4 7.693E-4 3 14
25 CID000107674 selenide ion Stitch 1.107E-7 3.264E-5 3.102E-4 8.336E-4 5 178
26 CID000064944 dichlorofluorescein Stitch 1.127E-7 3.264E-5 3.102E-4 8.487E-4 4 66
27 CID000104806 peroxynitrite Stitch 1.271E-7 3.544E-5 3.368E-4 9.568E-4 6 373
28 CID000447586 sulfenic acid Stitch 1.350E-7 3.631E-5 3.451E-4 1.017E-3 4 69
29 CID000001149 AC1L1AU5 Stitch 1.894E-7 4.630E-5 4.400E-4 1.426E-3 4 75
30 CID000164709 AC1L4VB4 Stitch 1.906E-7 4.630E-5 4.400E-4 1.435E-3 3 17
31 ctd:C026308 3,4-dihydrocoumarin CTD 1.906E-7 4.630E-5 4.400E-4 1.435E-3 3 17
32 ctd:D003671 DEET CTD 2.235E-7 5.260E-5 4.999E-4 1.683E-3 5 205
33 ctd:D047188 Chalcones CTD 2.714E-7 6.193E-5 5.886E-4 2.044E-3 3 19
34 CID000008343 DEHP Stitch 3.141E-7 6.957E-5 6.612E-4 2.365E-3 4 85
35 CID000137994 tempol Stitch 3.246E-7 6.983E-5 6.636E-4 2.444E-3 5 221
36 CID000062472 ethyl hydroperoxide Stitch 3.722E-7 7.785E-5 7.399E-4 2.803E-3 3 21
37 CID000021157 buthionine sulfoximine Stitch 3.871E-7 7.878E-5 7.487E-4 2.915E-3 5 229
38 CID000347590 S-ethyl N-phenylisothiourea Stitch 4.515E-7 8.056E-5 7.656E-4 3.399E-3 4 93
39 ctd:C063318 4-methoxycinnamic acid CTD 4.600E-7 8.056E-5 7.656E-4 3.464E-3 2 2
40 ctd:C031517 2-methyl-3-(4-(3-pyridinylmethyl)phenyl)-2-propenoic acid CTD 4.600E-7 8.056E-5 7.656E-4 3.464E-3 2 2
41 CID003080699 5-nitroso-salicylate Stitch 4.600E-7 8.056E-5 7.656E-4 3.464E-3 2 2
42 CID000127258 DL-040 Stitch 4.600E-7 8.056E-5 7.656E-4 3.464E-3 2 2
43 ctd:C519714 punicic acid CTD 4.600E-7 8.056E-5 7.656E-4 3.464E-3 2 2
44 CID000128682 dihydroethidium Stitch 4.918E-7 8.340E-5 7.926E-4 3.703E-3 4 95
45 ctd:D026023 Permethrin CTD 4.984E-7 8.340E-5 7.926E-4 3.753E-3 5 241
46 ctd:C025256 nonylphenol CTD 6.233E-7 1.020E-4 9.696E-4 4.693E-3 6 489
47 ctd:D001585 Benzoyl Peroxide CTD 7.260E-7 1.163E-4 1.106E-3 5.467E-3 3 26
48 ctd:D009249 NADP CTD 7.933E-7 1.230E-4 1.169E-3 5.973E-3 4 107
49 CID000413555 AC1L95SO Stitch 8.164E-7 1.230E-4 1.169E-3 6.148E-3 3 27
50 ctd:C057580 gallocatechol CTD 8.164E-7 1.230E-4 1.169E-3 6.148E-3 3 27
Show 45 more annotations

18: Disease [Display Chart] 15 input genes in category / 690 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1456865 Ureteral Calculi DisGeNET Curated 4.793E-6 3.307E-3 2.353E-2 3.307E-3 2 4
2 C0752351 Embryo Loss DisGeNET Curated 1.675E-5 5.134E-3 3.653E-2 1.156E-2 2 7
3 C1959583 Myocardial Failure DisGeNET BeFree 2.232E-5 5.134E-3 3.653E-2 1.540E-2 2 8
4 C0018203 Chronic granulomatous disease DisGeNET Curated 4.331E-5 7.472E-3
5.316E-2
 2.989E-2 3 76
5 C0033626 Protein Deficiency DisGeNET Curated 5.438E-5 7.505E-3
5.339E-2
 3.752E-2 3 82
6 C0085580 Essential Hypertension DisGeNET Curated 1.082E-4 1.185E-2
8.430E-2
7.469E-2
 4 284
7 C0011853 Diabetes Mellitus, Experimental DisGeNET Curated 1.202E-4 1.185E-2
8.430E-2
8.294E-2
 3 107
8 C0003949 Asbestosis DisGeNET Curated 2.566E-4 1.277E-2
9.088E-2
1.771E-1
 2 26
9 C0029456 Osteoporosis DisGeNET Curated 3.179E-4 1.277E-2
9.088E-2
2.193E-1
 4 376
10 C0043459 Zellweger Syndrome DisGeNET Curated 3.662E-4 1.277E-2
9.088E-2
2.526E-1
 2 31
11 C0022593 Keratosis DisGeNET Curated 4.153E-4 1.277E-2
9.088E-2
2.866E-1
 2 33
12 C3854173 Pre-renal acute kidney injury DisGeNET BeFree 4.410E-4 1.277E-2
9.088E-2
3.043E-1
 2 34
13 C0013080 Down Syndrome DisGeNET Curated 5.060E-4 1.277E-2
9.088E-2
3.492E-1
 4 425
14 C0392164 Pulmonary Cystic Fibrosis DisGeNET BeFree 5.515E-4 1.277E-2
9.088E-2
3.805E-1
 2 38
15 C0993582 Arthritis, Experimental DisGeNET Curated 6.112E-4 1.277E-2
9.088E-2
4.218E-1
 2 40
16 C1258104 Diffuse Scleroderma DisGeNET Curated 6.112E-4 1.277E-2
9.088E-2
4.218E-1
 2 40
17 C0917996 Cerebral Aneurysm DisGeNET BeFree 6.422E-4 1.277E-2
9.088E-2
4.432E-1
 2 41
18 C0221757 alpha 1-Antitrypsin Deficiency DisGeNET Curated 7.397E-4 1.277E-2
9.088E-2
5.104E-1
 2 44
19 C0022660 Kidney Failure, Acute DisGeNET Curated 7.663E-4 1.277E-2
9.088E-2
5.287E-1
 3 201
20 C1844376 Granulomatous Disease, Chronic, X-Linked DisGeNET Curated 7.737E-4 1.277E-2
9.088E-2
5.339E-1
 2 45
21 C0041107 Trisomy DisGeNET Curated 9.066E-4 1.277E-2
9.088E-2
6.255E-1
 3 213
22 C0585006 Deficiency of enoyl-CoA hydratase DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
23 C0001261 Actinomycosis DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
24 C0265604 Mirror hands DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
25 C0271454 Chronic purulent otitis media DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
26 C1865351 Hyperintense lesions in the basal ganglia on MRI DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
27 C4024620 Widened sacrosciatic notch DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
28 C4024926 Focal T2 hyperintense basal ganglia lesion DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
29 C0746604 Endocarditis of mitral valve DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
30 C1263758 Female genital tract infection DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
31 cv:C0685838 Gonadal dysgenesis with auditory dysfunction, autosomal recessive inheritance Clinical Variations 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
32 cv:C0342870 Bifunctional peroxisomal enzyme deficiency Clinical Variations 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
33 cv:C0268419 Acatalasemia Clinical Variations 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
34 OMIN:602473 ENCEPHALOPATHY, ETHYLMALONIC OMIM 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
35 C0333295 Acute ulcer DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
36 C1969532 Rhizomelic arm shortening DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
37 C4025218 Large vessel vasculitis DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
38 C1855230 Focal lissencephaly DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
39 C0752048 Hypocatalasemia DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
40 cv:C1865349 Ethylmalonic encephalopathy Clinical Variations 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
41 cv:C0398595 Myeloperoxidase deficiency Clinical Variations 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
42 C1533628 Pseudo-Zellweger syndrome DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
43 OMIN:254600 MYELOPEROXIDASE DEFICIENCY OMIM 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
44 C0282526 Hyperpipecolic Acidemia DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
45 C1855240 Irregular tarsal bones DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
46 C1536651 Arterial leg ulcer DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
47 C4022869 Reduced catalase activity DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
48 C2936847 Acatalasemia Japanese type DisGeNET BeFree 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
49 C1855229 Spondylometaphyseal dysplasia, Sedaghatian type DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
50 C4024945 Generalized cerebral atrophy/hypoplasia DisGeNET Curated 9.256E-4 1.277E-2
9.088E-2
6.387E-1
 1 1
Show 45 more annotations