|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
M3955
|
Integrin, VEGF, Wnt and TGFbeta signaling pathway genes up-regulated in PC-3 cells (prostate cancer) after knockdown of PDEF [GeneID=25803] by RNAi.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
5.502E-7
|
5.942E-4
|
4.493E-3
|
5.942E-4
|
3
|
71
|
2
|
M3495
|
Angiogenic and metastatic genes changed in RKO cells (colorectal cancer) upon perturbation of key components of AKT pathway.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.520E-6
|
1.361E-3
|
1.029E-2
|
2.721E-3
|
2
|
10
|
3
|
M2225
|
Genes down-regulated in osteoblasts from wild type male mice compared to those with AR [GeneID=367] knockout.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
9.565E-6
|
3.371E-3
|
2.549E-2
|
1.033E-2
|
2
|
19
|
4
|
M6634
|
Genes down-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] and 180 min stimulation of: LPS versus IL10 [GeneID=3486] and LPS.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.248E-5
|
3.371E-3
|
2.549E-2
|
1.348E-2
|
3
|
200
|
5
|
19458276-Table3
|
Mouse Stemcell Bol09 31genes
|
GeneSigDB
|
2.430E-5
|
3.981E-3
|
3.010E-2
|
2.624E-2
|
2
|
30
|
6
|
M19682
|
Genes down-regulated in huT78R cells (cutaneous T-cell lymphoma, CTCL) resistant to IFNA2 [GeneID=3440] compared to the IFN2A sensitive parental cell line.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.770E-5
|
3.981E-3
|
3.010E-2
|
2.992E-2
|
2
|
32
|
7
|
17295094-GeneList
|
Human Breast VandenEynden07 269genes-hypoxia angiogenesis
|
GeneSigDB
|
2.832E-5
|
3.981E-3
|
3.010E-2
|
3.058E-2
|
3
|
263
|
8
|
M1612
|
Strongly up-regulated at 2 h during differentiation of 3T3-L1 cells (fibroblast) into adipocytes.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.949E-5
|
3.981E-3
|
3.010E-2
|
3.184E-2
|
2
|
33
|
9
|
M1675
|
Selected genes up-regulated during differentiation of 3T3-L1 cells (fibroblast) into adipocytes in response to adipogenic hormones.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
6.555E-5
|
7.254E-3
|
5.486E-2
|
7.080E-2
|
2
|
49
|
10
|
M1597
|
Cluster 2: genes maximally expressed at 2 h time point during differentiation of 3T3-L1 fibroblasts into adipocytes (cluster 2) in response to adipogenic hormones.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
7.105E-5
|
7.254E-3
|
5.486E-2
|
7.674E-2
|
2
|
51
|
11
|
16585153-Table1
|
Mouse Skin Hagendoorn06 54genes
|
GeneSigDB
|
7.389E-5
|
7.254E-3
|
5.486E-2
|
7.980E-2
|
2
|
52
|
12
|
15696083-Table1
|
Human Lung Wang05 64genes
|
GeneSigDB
|
8.888E-5
|
7.999E-3
|
6.049E-2
|
9.599E-2
|
2
|
57
|
13
|
16618722-Table1
|
Human InVitro Glesne06 108genes
|
GeneSigDB
|
2.688E-4
|
2.233E-2
|
1.689E-1
|
2.903E-1
|
2
|
99
|
14
|
21205295-TableS2
|
Mouse Viral Buonomo11 116genes
|
GeneSigDB
|
3.024E-4
|
2.264E-2
|
1.712E-1
|
3.266E-1
|
2
|
105
|
15
|
M5922
|
Genes up-regulated during unfolded protein response, a cellular stress response related to the endoplasmic reticulum.
|
MSigDB H: Hallmark Gene Sets (v6.0)
|
3.501E-4
|
2.264E-2
|
1.712E-1
|
3.781E-1
|
2
|
113
|
16
|
16357179-Table2
|
Human Lymphoma Lecane05 131genes
|
GeneSigDB
|
4.214E-4
|
2.264E-2
|
1.712E-1
|
4.551E-1
|
2
|
124
|
17
|
17304354-Table2s
|
Human Lymphoma Piccaluga07 185genes
|
GeneSigDB
|
4.630E-4
|
2.264E-2
|
1.712E-1
|
5.001E-1
|
2
|
130
|
18
|
M5825
|
Angiogenic markers down-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
5.215E-4
|
2.264E-2
|
1.712E-1
|
5.633E-1
|
2
|
138
|
19
|
M2802
|
Genes up-regulated in primary keratinocytes from RB1 and RBL1 [Gene ID=5925, 5933] skin specific knockout mice.
|
MSigDB C6: Oncogenic Signatures (v6.0)
|
5.291E-4
|
2.264E-2
|
1.712E-1
|
5.714E-1
|
2
|
139
|
20
|
M2696
|
Genes up-regulated in HEK293 cells (kidney fibroblasts) upon knockdown of RELA [Gene ID=5970] gene by RNAi.
|
MSigDB C6: Oncogenic Signatures (v6.0)
|
6.075E-4
|
2.264E-2
|
1.712E-1
|
6.561E-1
|
2
|
149
|
21
|
M1484
|
Genes up-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
6.239E-4
|
2.264E-2
|
1.712E-1
|
6.738E-1
|
2
|
151
|
22
|
M9104
|
Genes down-regulated in CD4 T conv: control versus over-expression of IKZF4 and FOXP3 [GeneID=64375;50943].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
6.488E-4
|
2.264E-2
|
1.712E-1
|
7.007E-1
|
2
|
154
|
23
|
17183660-TableS1a
|
Mouse Breast Bacac06 256genes StromaUp
|
GeneSigDB
|
7.000E-4
|
2.264E-2
|
1.712E-1
|
7.560E-1
|
2
|
160
|
24
|
M15047
|
The 'NPM1 signature 3': genes down-regulated in pediatric AML (acute myeloid leukemia) with mutated NPM1 [GeneID=4869] compared to the AML cases with intact NPM1 and MLL [GeneID=4297].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
7.175E-4
|
2.264E-2
|
1.712E-1
|
7.749E-1
|
2
|
162
|
25
|
M12112
|
Angiogenic markers up-regulated in lymph endothelial cells upon infection with KSHV (Kaposi's sarcoma herpes virus).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
7.441E-4
|
2.264E-2
|
1.712E-1
|
8.037E-1
|
2
|
165
|
26
|
M6697
|
Genes up-regulated in endothelial cells: interferon alpha versus IFNG [GeneID=3458].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
7.531E-4
|
2.264E-2
|
1.712E-1
|
8.134E-1
|
2
|
166
|
27
|
M5649
|
Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMC from patients with acute S. pneumoniae infection.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
7.804E-4
|
2.264E-2
|
1.712E-1
|
8.428E-1
|
2
|
169
|
28
|
M6738
|
Genes up-regulated in T cells: CD4 [GeneID=920] versus CD8.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
8.943E-4
|
2.264E-2
|
1.712E-1
|
9.658E-1
|
2
|
181
|
29
|
M12621
|
Genes up-regulated in Wilm's tumor samples compared to fetal kidney.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
9.041E-4
|
2.264E-2
|
1.712E-1
|
9.764E-1
|
2
|
182
|
30
|
M19867
|
Genes down-regulated in acute myeloid leukemia (AML) with respect to cellular localization of NPM1 [GeneID=4869]: cytoplasmic vs. nucleolar.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
9.239E-4
|
2.264E-2
|
1.712E-1
|
9.978E-1
|
2
|
184
|
31
|
M3113
|
Genes up-regulated in comparison of effector memory T cells versus peripheral blood mononuclear cells (PBMC).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.079E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
199
|
32
|
M3359
|
Genes up-regulated in comparison of Th2 cells versus Th1 cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.079E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
199
|
33
|
M4946
|
Genes down-regulated in comparison of monocytes versus plasmacytoid dendritic cells (pDC).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.079E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
199
|
34
|
M5191
|
Genes down-regulated in comparison of dendritic cells (DC) exposed to M. tuberculosis versus macrophages exposed to L. major.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
35
|
M3078
|
Genes up-regulated in comparison of healthy CD4 [GeneID=920] T cells versus healthy myeloid cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
36
|
M6583
|
Genes down-regulated in monocytes: untreated versus CSF1 [GeneID=1435] knockout at day 3.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
37
|
M9186
|
Genes up-regulated in CD4 T conv over-expressing FOXP3 [GeneID=50943] versus GATA1 and FOXP3 [GeneID=2623;50943].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
38
|
M3116
|
Genes up-regulated in comparison of central memory T cells versus peripheral blood mononuclear cells (PBMC).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
39
|
M3613
|
Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after stimulation with antigen-B7-1.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
40
|
M4693
|
Genes up-regulated in comparison of unstimulated dendritic cells (DC) at 0 h versus DCs stimulated with R848 for 8 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
41
|
M9748
|
Genes up-regulated in Ly6c int CXCR5+ CD4 [GeneID=643;920] T cells: effector during acute infection of LCMV versus memory.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
42
|
M6247
|
Genes down-regulated in immature CD4 [GeneID=920] single positive cells versus double positive thymocytes.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
43
|
M3610
|
Genes down-regulated in comparison of CD8 T cells at 0 h versus those at 72 h after stimulation with IL12.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
44
|
M6587
|
Genes down-regulated in monocytes versus classically activated (M1) macrophages.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
45
|
M5381
|
Genes up-regulated in comparison of memory CD4 [GeneID=920] T cells versus Th2 cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
46
|
M6538
|
Genes down-regulated in epithelial cells (6h): interferon alpha versus interferon alpha and IFNG [GeneID=3458].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
47
|
M3084
|
Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus B cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
48
|
M4143
|
Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
49
|
M8959
|
Genes up-regulated in lymph node from aged PPARG [GeneID=5468] knockout mice: T reg versus T conv.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|
50
|
M3121
|
Genes down-regulated in comparison of peripheral mononuclear blood cells (PBMC) versus memory T cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.090E-3
|
2.264E-2
|
1.712E-1
|
1.000E0
|
2
|
200
|