Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc317_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 4 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0008519 ammonium transmembrane transporter activity 6.301E-15 2.520E-14 5.251E-14 2.520E-14 5 29
2 GO:0015077 monovalent inorganic cation transmembrane transporter activity 3.192E-9 6.384E-9 1.330E-8 1.277E-8 5 375
3 GO:0030506 ankyrin binding 1.226E-8 1.635E-8 3.407E-8 4.906E-8 3 21
4 GO:0035379 carbon dioxide transmembrane transporter activity 5.358E-4 5.358E-4 1.116E-3 2.143E-3 1 2

2: GO: Biological Process [Display Chart] 5 input genes in category / 26 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0019740 nitrogen utilization 3.002E-18 7.804E-17 3.008E-16 7.804E-17 5 8
2 GO:0015695 organic cation transport 1.412E-15 1.835E-14 7.073E-14 3.670E-14 5 22
3 GO:0072488 ammonium transmembrane transport 2.848E-15 2.468E-14 9.513E-14 7.404E-14 5 25
4 GO:0015696 ammonium transport 9.789E-12 6.363E-11 2.453E-10 2.545E-10 5 119
5 GO:0060586 multicellular organismal iron ion homeostasis 1.532E-9 7.967E-9 3.071E-8 3.983E-8 3 11
6 GO:0048821 erythrocyte development 4.598E-8 1.992E-7 7.679E-7 1.195E-6 3 32
7 GO:0070634 transepithelial ammonium transport 1.730E-7 6.425E-7 2.477E-6 4.498E-6 2 3
8 GO:0061515 myeloid cell development 4.428E-7 1.439E-6 5.547E-6 1.151E-5 3 67
9 GO:0055072 iron ion homeostasis 6.756E-7 1.952E-6 7.523E-6 1.757E-5 3 77
10 GO:0030218 erythrocyte differentiation 2.156E-6 5.606E-6 2.161E-5 5.606E-5 3 113
11 GO:0055076 transition metal ion homeostasis 2.585E-6 6.033E-6 2.325E-5 6.721E-5 3 120
12 GO:0034101 erythrocyte homeostasis 2.785E-6 6.033E-6 2.325E-5 7.240E-5 3 123
13 GO:0002262 myeloid cell homeostasis 4.961E-6 9.922E-6 3.824E-5 1.290E-4 3 149
14 GO:0070633 transepithelial transport 6.047E-6 1.123E-5 4.329E-5 1.572E-4 2 15
15 GO:0048872 homeostasis of number of cells 3.184E-5 5.519E-5 2.127E-4 8.279E-4 3 277
16 GO:0048871 multicellular organismal homeostasis 8.049E-5 1.308E-4 5.041E-4 2.093E-3 3 378
17 GO:0030099 myeloid cell differentiation 8.699E-5 1.330E-4 5.128E-4 2.262E-3 3 388
18 GO:0035378 carbon dioxide transmembrane transport 5.369E-4 7.755E-4 2.989E-3 1.396E-2 1 2
19 GO:0015670 carbon dioxide transport 2.146E-3 2.937E-3 1.132E-2
5.580E-2
 1 8
20 GO:0019755 one-carbon compound transport 4.556E-3 5.923E-3 2.283E-2
1.185E-1
 1 17
21 GO:0015669 gas transport 6.161E-3 7.627E-3 2.940E-2
1.602E-1
 1 23
22 GO:0015701 bicarbonate transport 1.202E-2 1.421E-2
5.478E-2
3.126E-1
 1 45
23 GO:0015837 amine transport 2.656E-2 2.935E-2
1.131E-1
6.907E-1
 1 100
24 GO:0006885 regulation of pH 2.709E-2 2.935E-2
1.131E-1
7.043E-1
 1 102
25 GO:0055067 monovalent inorganic cation homeostasis 4.171E-2 4.338E-2
1.672E-1
1.000E0
 1 158
Show 20 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 8 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016323 basolateral plasma membrane 1.591E-3 8.388E-3 2.280E-2 1.273E-2 2 244
2 GO:0014731 spectrin-associated cytoskeleton 2.097E-3 8.388E-3 2.280E-2 1.678E-2 1 8
3 GO:0009925 basal plasma membrane 1.123E-2 2.454E-2
6.669E-2
8.984E-2
 1 43
4 GO:0046658 anchored component of plasma membrane 1.227E-2 2.454E-2
6.669E-2
9.816E-2
 1 47
5 GO:0045178 basal part of cell 1.668E-2 2.668E-2
7.252E-2
1.334E-1
 1 64

4: Human Phenotype [Display Chart] 2 input genes in category / 19 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0004446 Stomatocytosis 8.216E-6 1.561E-4 5.538E-4 1.561E-4 2 14
2 HP:0003575 Increased intracellular sodium 4.249E-4 4.037E-3 1.432E-2 8.073E-3 1 1
3 HP:0005502 Increased red cell osmotic fragility 1.274E-3 6.986E-3 2.479E-2 2.421E-2 1 3
4 HP:0004447 Poikilocytosis 1.471E-3 6.986E-3 2.479E-2 2.795E-2 2 181
5 HP:0001878 Hemolytic anemia 2.419E-3 7.661E-3 2.718E-2 4.597E-2 2 232
6 HP:0011895 Anemia due to reduced life span of red cells 2.419E-3 7.661E-3 2.718E-2 4.597E-2 2 232
7 HP:0008282 Unconjugated hyperbilirubinemia 1.945E-2 4.820E-2
1.710E-1
3.696E-1
 1 46
8 HP:0004870 Chronic hemolytic anemia 2.029E-2 4.820E-2
1.710E-1
3.856E-1
 1 48
Show 3 more annotations

5: Mouse Phenotype [Display Chart] 5 input genes in category / 35 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0008810 increased circulating iron level 1.118E-6 2.602E-5 1.079E-4 3.912E-5 3 51
2 MP:0003656 abnormal erythrocyte physiology 1.487E-6 2.602E-5 1.079E-4 5.204E-5 3 56
3 MP:0011736 decreased urine ammonia level 2.796E-6 3.262E-5 1.353E-4 9.786E-5 2 6
4 MP:0004152 abnormal circulating iron level 6.701E-6 4.694E-5 1.947E-4 2.345E-4 3 92
5 MP:0011734 abnormal urine ammonia level 6.706E-6 4.694E-5 1.947E-4 2.347E-4 2 9
6 MP:0006357 abnormal circulating mineral level 2.252E-5 1.276E-4 5.292E-4 7.883E-4 4 483
7 MP:0001770 abnormal iron level 2.581E-5 1.276E-4 5.292E-4 9.033E-4 3 144
8 MP:0005637 abnormal iron homeostasis 2.917E-5 1.276E-4 5.292E-4 1.021E-3 3 150
9 MP:0030604 abnormal ammonia homeostasis 7.534E-5 2.930E-4 1.215E-3 2.637E-3 2 29
10 MP:0005642 decreased mean corpuscular hemoglobin concentration 3.600E-4 1.182E-3 4.903E-3 1.260E-2 2 63
11 MP:0002966 decreased circulating alkaline phosphatase level 3.716E-4 1.182E-3 4.903E-3 1.301E-2 2 64
12 MP:0005640 abnormal mean corpuscular hemoglobin concentration 8.527E-4 2.487E-3 1.031E-2 2.984E-2 2 97
13 MP:0002591 decreased mean corpuscular volume 1.480E-3 3.984E-3 1.652E-2
5.179E-2
 2 128
14 MP:0002874 decreased hemoglobin content 3.750E-3 9.375E-3 3.887E-2
1.312E-1
 2 205
15 MP:0000525 renal tubular acidosis 5.301E-3 1.237E-2
5.129E-2
1.855E-1
 1 11
16 MP:0000226 abnormal mean corpuscular volume 6.200E-3 1.285E-2
5.328E-2
2.170E-1
 2 265
17 MP:0001191 abnormal skin condition 6.338E-3 1.285E-2
5.328E-2
2.218E-1
 2 268
18 MP:0009349 increased urine pH 6.743E-3 1.285E-2
5.328E-2
2.360E-1
 1 14
19 MP:0005563 abnormal hemoglobin content 7.292E-3 1.285E-2
5.328E-2
2.552E-1
 2 288
20 MP:0000202 abnormal circulating alkaline phosphatase level 7.341E-3 1.285E-2
5.328E-2
2.570E-1
 2 289
21 MP:0009348 abnormal urine pH 1.488E-2 2.480E-2
1.029E-1
5.209E-1
 1 31
22 MP:0003031 acidosis 1.584E-2 2.519E-2
1.045E-1
5.543E-1
 1 33
23 MP:0009643 abnormal urine homeostasis 1.892E-2 2.878E-2
1.194E-1
6.620E-1
 2 472
24 MP:0001588 abnormal hemoglobin 1.992E-2 2.905E-2
1.205E-1
6.973E-1
 2 485
25 MP:0005628 decreased circulating potassium level 2.392E-2 3.219E-2
1.335E-1
8.370E-1
 1 50
26 MP:0004043 abnormal pH regulation 2.392E-2 3.219E-2
1.335E-1
8.370E-1
 1 50
27 MP:0003014 abnormal kidney medulla morphology 3.335E-2 4.287E-2
1.778E-1
1.000E0
 1 70
28 MP:0004754 abnormal kidney collecting duct morphology 3.429E-2 4.287E-2
1.778E-1
1.000E0
 1 72
Show 23 more annotations

6: Domain [Display Chart] 5 input genes in category / 6 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR002229 RhesusRHD InterPro 5.202E-20 7.803E-20 1.912E-19 3.121E-19 5 5
2 IPR001905 Ammonium transpt InterPro 5.202E-20 7.803E-20 1.912E-19 3.121E-19 5 5
3 IPR024041 NH4 transpt AmtB-like dom InterPro 5.202E-20 7.803E-20 1.912E-19 3.121E-19 5 5
4 PF00909 Ammonium transp Pfam 5.202E-20 7.803E-20 1.912E-19 3.121E-19 5 5
5 1.10.3430.10 - Gene3D 1.092E-18 1.092E-18 2.676E-18 6.554E-18 5 7
6 IPR029020 Ammonium/urea transptr InterPro 1.092E-18 1.092E-18 2.676E-18 6.554E-18 5 7
Show 1 more annotation

7: Pathway [Display Chart] 3 input genes in category / 6 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269935 Rhesus glycoproteins mediate ammonium transport. BioSystems: REACTOME 3.110E-12 1.866E-11 4.572E-11 1.866E-11 3 3
2 1269923 Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds BioSystems: REACTOME 6.000E-7 1.800E-6 4.410E-6 3.600E-6 3 106
3 1269907 SLC-mediated transmembrane transport BioSystems: REACTOME 1.213E-5 2.425E-5 5.941E-5 7.275E-5 3 287
4 1270225 Erythrocytes take up oxygen and release carbon dioxide BioSystems: REACTOME 2.167E-3 3.130E-3 7.667E-3 1.300E-2 1 9
5 1270223 O2/CO2 exchange in erythrocytes BioSystems: REACTOME 3.130E-3 3.130E-3 7.667E-3 1.878E-2 1 13
6 1270224 Erythrocytes take up carbon dioxide and release oxygen BioSystems: REACTOME 3.130E-3 3.130E-3 7.667E-3 1.878E-2 1 13
Show 1 more annotation

8: Pubmed [Display Chart] 5 input genes in category / 314 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16227429 Evolutionary conservation and diversification of Rh family genes and proteins. Pubmed 1.477E-21 4.638E-19 2.935E-18 4.638E-19 5 5
2 16563829 Transport characteristics of mammalian Rh and Rh glycoproteins expressed in heterologous systems. Pubmed 5.640E-17 8.856E-15 5.604E-14 1.771E-14 4 4
3 15929723 Human Rhesus B and Rhesus C glycoproteins: properties of facilitated ammonium transport in recombinant kidney cells. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
4 16584906 Hydrophobic cluster analysis and modeling of the human Rh protein three-dimensional structures. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
5 26354748 Mechanisms of ammonia and ammonium transport by rhesus-associated glycoproteins. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
6 3146980 Protein-sequence studies on Rh-related polypeptides suggest the presence of at least two groups of proteins which associate in the human red-cell membrane. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
7 19807729 Generation and characterisation of Rhd and Rhag null mice. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
8 24077989 Relative COâ??/NHâ?? permeabilities of human RhAG, RhBG and RhCG. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
9 9705835 Conserved evolution of the Rh50 gene compared to its homologous Rh blood group gene. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
10 9929383 The members of the RH gene family (RH50 and RH30) followed different evolutionary pathways. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
11 10970100 Evolutionary history of the Rh blood group-related genes in vertebrates. Pubmed 1.077E-12 3.074E-11 1.946E-10 3.382E-10 3 3
12 10495887 The mouse Rhl1 and Rhag genes: sequence, organization, expression, and chromosomal mapping. Pubmed 2.154E-11 5.636E-10 3.566E-9 6.763E-9 3 6
13 16564724 The challenge of understanding ammonium homeostasis and the role of the Rh glycoproteins. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
14 23550903 A convenient qualitative and quantitative method to investigate RHD-RHCE hybrid genes. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
15 8808597 Genetic recombination at the human RH locus: a family study of the red-cell Evans phenotype reveals a transfer of exons 2-6 from the RHD to the RHCE gene. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
16 3135863 Determination of the N-terminal sequence of human red cell Rh(D) polypeptide and demonstration that the Rh(D), (c), and (E) antigens are carried by distinct polypeptide chains. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
17 11724987 E variants found in Japanese and c antigenicity alteration without substitution in the second extracellular loop. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
18 1898705 Regarding the size of Rh proteins. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
19 22804620 RHCE*ceTI encodes partial c and partial e and is often in cis to RHD*DIVa. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
20 11062476 The human Rhesus-associated RhAG protein and a kidney homologue promote ammonium transport in yeast. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
21 8822955 Alteration of RH gene structure and expression in human dCCee and DCW-red blood cells: phenotypic homozygosity versus genotypic heterozygosity. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
22 23742316 RHD*weak partial 4.0 is associated with an altered RHCE*ce(48C, 105T, 733G, 744C, 1025T) allele in the Tunisian population. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
23 15798090 Apical ammonia transport by the mouse inner medullary collecting duct cell (mIMCD-3). Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
24 1379850 Multiple Rh messenger RNA isoforms are produced by alternative splicing. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
25 16580864 Electrogenic ammonium transport by renal Rhbg. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
26 12201845 Molecular background of Rh D-positive, D-negative, D(el) and weak D phenotypes in Chinese. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
27 27111588 RHCE variants inherited with altered RHD alleles in Brazilian blood donors. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
28 16563831 Rh glycoproteins in epithelial cells: lessons from rat and mice studies. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
29 7916743 Isolation of a new cDNA clone encoding an Rh polypeptide associated with the Rh blood group system. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
30 22738288 The low-prevalence Rh antigen STEM (RH49) is encoded by two different RHCE*ce818T alleles that are often in cis to RHD*DOL. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
31 12130520 Cell-surface expression of RhD blood group polypeptide is posttranscriptionally regulated by the RhAG glycoprotein. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
32 11161244 PCR screening for common weak D types shows different distributions in three Central European populations. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
33 12084172 Molecular background of D(C)(e) haplotypes within the white population. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
34 25857637 RH diversity in Mali: characterization of a new haplotype RHD*DIVa/RHCE*ceTI(D2). Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
35 22690701 RHD*DOL1 and RHD*DOL2 encode a partial D antigen and are in cis with the rare RHCE*ceBI allele in people of African descent. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
36 17900276 DCS-1, DCS-2, and DFV share amino acid substitutions at the extracellular RhD protein vestibule. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
37 1438298 Molecular cloning and primary structure of the human blood group RhD polypeptide. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
38 23904565 Expression of the rhesus glycoproteins, ammonia transporter family members, RHCG and RHBG in male reproductive organs. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
39 10329015 Characterization of the mouse Rh blood group gene. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
40 16564723 Expression of the non-erythroid Rh glycoproteins in mammalian tissues. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
41 26579938 Intron 4 of the RH Gene in Han Chinese, Tibetan, and Mongol Populations. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
42 8220426 Molecular genetic basis of the human Rhesus blood group system. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
43 1417776 Isolation of cDNA clones for a 50 kDa glycoprotein of the human erythrocyte membrane associated with Rh (rhesus) blood-group antigen expression. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
44 24960646 Variant RH alleles and Rh immunisation in patients with sickle cell disease. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
45 24647713 Ammonia transport in the kidney by Rhesus glycoproteins. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
46 12846905 The Rh complex exports ammonium from human red blood cells. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
47 29193104 Transfusion strategy for weak D Type 4.0 based on RHD alleles and RH haplotypes in Tunisia. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
48 10627438 The Rh blood group system: a review. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
49 23772606 RHCE*ceMO is frequently in cis to RHD*DAU0 and encodes a hr(S) -, hr(B) -, RH:-61 phenotype in black persons: clinical significance. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
50 24033223 A comprehensive survey of both RHD and RHCE allele frequencies in sub-Saharan Africa. Pubmed 1.371E-8 6.240E-8 3.949E-7 4.305E-6 2 2
Show 45 more annotations

9: Interaction [Display Chart] 4 input genes in category / 12 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:RHBG RHBG interactions 4.519E-4 1.807E-3 5.609E-3 5.422E-3 1 2
2 int:RHD RHD interactions 4.519E-4 1.807E-3 5.609E-3 5.422E-3 1 2
3 int:RHCG RHCG interactions 4.519E-4 1.807E-3 5.609E-3 5.422E-3 1 2
4 int:RHAG RHAG interactions 1.581E-3 4.743E-3 1.472E-2 1.897E-2 1 7
5 int:ICAM4 ICAM4 interactions 2.709E-3 6.501E-3 2.017E-2 3.251E-2 1 12
6 int:SLC4A1 SLC4A1 interactions 4.287E-3 7.734E-3 2.400E-2
5.144E-2
 1 19
7 int:SH2B1 SH2B1 interactions 4.512E-3 7.734E-3 2.400E-2
5.414E-2
 1 20
8 int:SCARB2 SCARB2 interactions 6.537E-3 9.316E-3 2.891E-2
7.844E-2
 1 29
9 int:ANK1 ANK1 interactions 6.987E-3 9.316E-3 2.891E-2
8.384E-2
 1 31
10 int:CD47 CD47 interactions 7.886E-3 9.463E-3 2.936E-2
9.463E-2
 1 35
11 int:BAZ1B BAZ1B interactions 1.103E-2 1.125E-2 3.491E-2
1.323E-1
 1 49
12 int:GYPB GYPB interactions 1.125E-2 1.125E-2 3.491E-2
1.350E-1
 1 50
Show 7 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 4 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1p36.11 1p36.11 3.778E-5 1.511E-4 3.148E-4 1.511E-4 2 68
2 15q25 15q25 1.154E-3 2.307E-3 4.807E-3 4.614E-3 1 8
3 6p12.3 6p12.3 5.326E-3 7.102E-3 1.480E-2 2.131E-2 1 37
4 1q21.3 1q21.3 1.691E-2 1.691E-2 3.522E-2
6.763E-2
 1 118

11: Transcription Factor Binding Site [Display Chart] 4 input genes in category / 19 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$GATA C V$GATA C 4.194E-5 6.173E-4 2.190E-3 7.969E-4 3 216
2 GATAAGR V$GATA C GATAAGR V$GATA C 6.498E-5 6.173E-4 2.190E-3 1.235E-3 3 250
3 V$GATA Q6 V$GATA Q6 1.704E-3 3.779E-3 1.341E-2 3.237E-2 2 167
4 V$E2F Q3 V$E2F Q3 1.912E-3 3.779E-3 1.341E-2 3.633E-2 2 177
5 V$E2F1 Q4 01 V$E2F1 Q4 01 1.998E-3 3.779E-3 1.341E-2 3.797E-2 2 181
6 V$E2F Q6 V$E2F Q6 2.020E-3 3.779E-3 1.341E-2 3.839E-2 2 182
7 V$E2F1DP1RB 01 V$E2F1DP1RB 01 2.065E-3 3.779E-3 1.341E-2 3.923E-2 2 184
8 V$E2F Q4 V$E2F Q4 2.065E-3 3.779E-3 1.341E-2 3.923E-2 2 184
9 V$E2F Q3 01 V$E2F Q3 01 2.109E-3 3.779E-3 1.341E-2 4.008E-2 2 186
10 V$E2F1 Q4 V$E2F1 Q4 2.177E-3 3.779E-3 1.341E-2 4.136E-2 2 189
11 V$E2F 03 V$E2F 03 2.223E-3 3.779E-3 1.341E-2 4.224E-2 2 191
12 V$GATA3 01 V$GATA3 01 2.387E-3 3.779E-3 1.341E-2 4.535E-2 2 198
13 V$SMAD Q6 V$SMAD Q6 2.606E-3 3.809E-3 1.351E-2 4.952E-2 2 207
Show 8 more annotations

12: Gene Family [Display Chart] 5 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 454 Blood group antigens genenames.org 7.720E-8 2.316E-7 4.246E-7 2.316E-7 3 37
2 471 CD molecules|Tumor necrosis factor superfamily genenames.org 9.758E-5 9.832E-5 1.802E-4 2.927E-4 3 394
3 752 Solute carriers genenames.org 9.832E-5 9.832E-5 1.802E-4 2.950E-4 3 395

13: Coexpression [Display Chart] 5 input genes in category / 227 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5945 Genes involved in metabolism of heme (a cofactor consisting of iron and porphyrin) and erythroblast differentiation. MSigDB H: Hallmark Gene Sets (v6.0) 6.282E-6 1.066E-3 6.402E-3 1.426E-3 3 200
2 M6241 Top 40 genes from cluster 8 of aculte myeloid leukemia (AML) expression profile; 69% of the samples are FAB M2 subtype. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.212E-5 1.066E-3 6.402E-3 2.751E-3 2 26
3 M8696 Top 40 genes from cluster 7 of acute myeloid leukemia (AML) expression profile; 61% of the samples are FAB M1 or M2 subtype. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.409E-5 1.066E-3 6.402E-3 3.199E-3 2 28
4 17174972-TableS1 Human Zola07 426genes CellDifferentiationMarkers GeneSigDB 3.215E-5 1.749E-3 1.050E-2 7.297E-3 3 345
5 16597596-TableS1-2 Human Leukemia Wilson06 50genes SigDifferentialClusterB1 GeneSigDB 3.852E-5 1.749E-3 1.050E-2 8.745E-3 2 46
6 M2222 Genes down-regulated in K562 cells (lymphoblast) by MYC [GeneID=4609] in the presence of CKN1B [GeneID=1027]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.468E-4 9.291E-3
5.578E-2
5.601E-2
 2 116
7 M2956 Genes down-regulated in induced T reg cultured with IL2 [GeneID=3558]: wildtype versus non-functional FOXP3 [GeneID=50943]. MSigDB C7: Immunologic Signatures (v6.0) 2.865E-4 9.291E-3
5.578E-2
6.503E-2
 2 125
8 M9930 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 3h. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 1.659E-2
9.962E-2
1.643E-1
 2 199
9 M7489 Genes up-regulated in NCAM+ [GeneID=4684] NK cells: SELL bright [GeneID=6402] versus SELL dim [GeneID=6402]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.659E-2
9.962E-2
1.659E-1
 2 200
10 M3055 Genes up-regulated in comparison of memory CD8 T cells versus effector CD8 T cells KLRG1 intermediate [GeneID=10219]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.659E-2
9.962E-2
1.659E-1
 2 200
11 M6905 Genes down-regulated in CD133+ [GeneID=8842] cells (hematopoietic stem cells, HSC) compared to the CD133- cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.317E-4 1.923E-2
1.154E-1
2.115E-1
 2 226
12 M2206 Genes down-regulated in immature bone marrow progenitor cells upon knock out of CBFA2T3 [GeneID=863]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.067E-3 2.019E-2
1.212E-1
2.422E-1
 2 242
13 M2246 Category D genes: p53-independent genes whose expression in the absence of S389 phosphorylation is similar to loss of TP53 [GeneID=7157] in MEF (embryonic fibroblast) cells in response to UV-C irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.425E-3 2.488E-2
1.494E-1
3.234E-1
 2 280
14 M11205 Genes in the expression cluster 'MBC Shared': up-regulated in mature blood cell populations from adult bone marrow and fetal liver. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.558E-3 2.527E-2
1.517E-1
3.538E-1
 2 293
15 17982488-TableS2b Human Colon Scian08 11genes GeneSigDB 2.375E-3 3.370E-2
2.023E-1
5.391E-1
 1 11
16 M7918 Genes that were inversely correlated in H1299 cells (lung cancer): up-regulated by P53 [GeneID=7157] and down-regulated by P73 [GeneID=7161]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.375E-3 3.370E-2
2.023E-1
5.391E-1
 1 11
17 M1925 Up-regulated genes in hepatocellular carcinoma (HCC) subclass G56, defined by unsupervised clustering. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.591E-3 3.430E-2
2.060E-1
5.881E-1
 1 12
18 M19476 Genes up-regulated in dividing CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloid leukemia) patients compared to the dividing cells from normal donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.806E-3 3.430E-2
2.060E-1
6.371E-1
 1 13
19 12869505-Table2 Mouse StemCell Kolbus03 22genes GeneSigDB 3.022E-3 3.430E-2
2.060E-1
6.860E-1
 1 14
20 14969821-Table2 Human Mouth Tsai04 29genes GeneSigDB 3.022E-3 3.430E-2
2.060E-1
6.860E-1
 1 14
21 19061838-TableS4a Human Viral Cairo08 16genes UpRegulated GeneSigDB 3.453E-3 3.733E-2
2.241E-1
7.839E-1
 1 16
22 19525976-Table1a Human Lung Chitale09 25genes EGFR GeneSigDB 4.100E-3 4.230E-2
2.540E-1
9.306E-1
 1 19
23 M12086 Genes up-regulated in hematopoietic stem cells (HSC) overexpressing a constitutively active form of STAT5 [GeneID=6776] off retroviral vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.530E-3 4.471E-2
2.685E-1
1.000E0
 1 21
24 16353136-Table4 Human Uterine Wong05 28genes GeneSigDB 5.822E-3 4.681E-2
2.811E-1
1.000E0
 1 27
25 18844975-Table1a Rat Immune vanRoon-Mom08 54genes GeneSigDB 7.112E-3 4.681E-2
2.811E-1
1.000E0
 1 33
26 15955831-Table4 Human StemCell Komor05 39genes GeneSigDB 8.400E-3 4.681E-2
2.811E-1
1.000E0
 1 39
27 M5916 Genes encoding proteins over-represented on the apical surface of epithelial cells, e.g., important for cell polarity (apical area). MSigDB H: Hallmark Gene Sets (v6.0) 9.473E-3 4.681E-2
2.811E-1
1.000E0
 1 44
28 16597596-TableS3-2 Human Leukemia Wilson06 50genes DifferentialClusterB GeneSigDB 9.688E-3 4.681E-2
2.811E-1
1.000E0
 1 45
29 15869706-Table3 Human Cervical Rosty05 51genes GeneSigDB 9.902E-3 4.681E-2
2.811E-1
1.000E0
 1 46
30 16597596-TableS3-4 Human Leukemia Wilson06 50genes SigDifferentialClusterD2 GeneSigDB 1.012E-2 4.681E-2
2.811E-1
1.000E0
 1 47
31 18510698-Table1 Human StemCell Lim08 50genes GeneSigDB 1.033E-2 4.681E-2
2.811E-1
1.000E0
 1 48
32 M2899 Genes up-regulated among the high recurrence rate urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.055E-2 4.681E-2
2.811E-1
1.000E0
 1 49
33 15955831-Table7 Human StemCell Komor05 52genes GeneSigDB 1.076E-2 4.681E-2
2.811E-1
1.000E0
 1 50
34 M14353 All marker genes down-regulated in the 'interferon' subclass of hepatocellular carcinoma (HCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.119E-2 4.681E-2
2.811E-1
1.000E0
 1 52
35 17409405-Table1a Human Breast Huper07 66genes BasalCells GeneSigDB 1.140E-2 4.681E-2
2.811E-1
1.000E0
 1 53
36 M13422 Genes up-regulated in basal mammary epithelial cells compared to the luminal ones. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.162E-2 4.681E-2
2.811E-1
1.000E0
 1 54
37 M17730 Genes up-regulated in quescent CD34+ [GeneID=8842] cells isolated from peripheral blood of CML (chronic myeloblastic leukemia) patients compared to the dividing cells from normal donors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.226E-2 4.681E-2
2.811E-1
1.000E0
 1 57
38 19356222-SuppTable5 Human Colon Daemen09 64genes GeneSigDB 1.269E-2 4.681E-2
2.811E-1
1.000E0
 1 59
39 19061838-TableS12 Human Viral Cairo08 61genes GeneSigDB 1.269E-2 4.681E-2
2.811E-1
1.000E0
 1 59
40 18310659-TableS2 Human Viral Maruyama08 64genes GeneSigDB 1.333E-2 4.681E-2
2.811E-1
1.000E0
 1 62
41 M1445 Genes down-regulated in day 6 embryoid bodies derived from embryonic stem cells (ES) with HEX [GeneID=3087] knockout. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.397E-2 4.681E-2
2.811E-1
1.000E0
 1 65
42 19061838-TableS4b Human Viral Cairo08 78genes GeneSigDB 1.461E-2 4.681E-2
2.811E-1
1.000E0
 1 68
43 18516279-GeneList Human Breast Kenny07 96genes 2Dv3Dcultures GeneSigDB 1.461E-2 4.681E-2
2.811E-1
1.000E0
 1 68
44 M4621 Top 100 probe sets for pediatric acute myeloid leukemia (AML) subtype FAB M7 (also known as acute megakaryoblastic leukemia, AMKL). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.461E-2 4.681E-2
2.811E-1
1.000E0
 1 68
45 M2533 Genes representing epithelial differentiation module in sputum during asthma exacerbations. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.482E-2 4.681E-2
2.811E-1
1.000E0
 1 69
46 M13658 Genes whose expression correlated with lower risk of late recurrence of hepatocellular carcinoma (HCC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.482E-2 4.681E-2
2.811E-1
1.000E0
 1 69
47 M17535 Genes from chromosomal copy number losses in a panel of 51 primary colon carcinoma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.589E-2 4.681E-2
2.811E-1
1.000E0
 1 74
48 M13396 Down-regulated genes in the B lymphocyte developmental signature, based on expression profiling of lymphomas from the Emu-myc transgenic mice: the Small Pre-BII stage. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.632E-2 4.681E-2
2.811E-1
1.000E0
 1 76
49 19525976-SuppTable5b Human Lung Chitale09 103genes GeneSigDB 1.696E-2 4.681E-2
2.811E-1
1.000E0
 1 79
50 16249385-Table3 Human Leukemia Ge06 106genes GeneSigDB 1.781E-2 4.681E-2
2.811E-1
1.000E0
 1 83
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 208 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PP epoMEP 1000 K2 PP epoMEP top-relative-expression-ranked 1000 k-means-cluster#2 PCBC 1.202E-6 2.501E-4 1.480E-3 2.501E-4 3 109
2 PP MEP 1000 K1 PP MEP top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 3.896E-6 3.652E-4 2.161E-3 8.103E-4 3 161
3 PP MEG 2500 K1 PP MEG top-relative-expression-ranked 2500 k-means-cluster#1 PCBC 5.268E-6 3.652E-4 2.161E-3 1.096E-3 3 178
4 PP RBC 500 K2 PP RBC top-relative-expression-ranked 500 k-means-cluster#2 PCBC 9.416E-6 4.897E-4 2.897E-3 1.959E-3 3 216
5 bone marrow bone marrow Human Protein Atlas 2.346E-5 9.761E-4 5.776E-3 4.881E-3 3 293
6 PP epoMEP 2500 K4 PP epoMEP top-relative-expression-ranked 2500 k-means-cluster#4 PCBC 5.221E-5 1.776E-3 1.051E-2 1.086E-2 3 383
7 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 100 k2 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 5.978E-5 1.776E-3 1.051E-2 1.243E-2 2 54
8 PP RBC 1000 K4 PP RBC top-relative-expression-ranked 1000 k-means-cluster#4 PCBC 7.118E-5 1.851E-3 1.095E-2 1.481E-2 3 425
9 GSM854317 100 Myeloid Cells, MF.BM, B220neg CD3neg Ly-6C/Glo CD115int F4/80+, Bone marrow, avg-3 Immgen.org, GSE15907 1.036E-4 2.144E-3 1.269E-2 2.156E-2 2 71
10 PP RBC 500 PP RBC top-relative-expression-ranked 500 PCBC 1.120E-4 2.144E-3 1.269E-2 2.330E-2 3 495
11 PP MEP 2500 K2 PP MEP top-relative-expression-ranked 2500 k-means-cluster#2 PCBC 1.134E-4 2.144E-3 1.269E-2 2.358E-2 3 497
12 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 100 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.317E-4 2.160E-3 1.278E-2 2.739E-2 2 80
13 PP MEG 1000 K5 PP MEG top-relative-expression-ranked 1000 k-means-cluster#5 PCBC 1.350E-4 2.160E-3 1.278E-2 2.808E-2 2 81
14 PP MEP 500 K1 PP MEP top-relative-expression-ranked 500 k-means-cluster#1 PCBC 1.487E-4 2.209E-3 1.307E-2 3.093E-2 2 85
15 GSM791108 100 Stem Cells, SC.MEP.BM, Lineage- Kit+ Sca1- CD34- FcgR-/low, Bone marrow, avg-2 Immgen.org, GSE15907 1.631E-4 2.261E-3 1.338E-2 3.392E-2 2 89
16 PP RBC 100 PP RBC top-relative-expression-ranked 100 PCBC 2.059E-4 2.677E-3 1.584E-2 4.283E-2 2 100
17 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 200 k3 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 2.676E-4 3.274E-3 1.937E-2
5.566E-2
 2 114
18 Kidney10XCellRanger Six2KI E14 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2KI E14 Eryth Eryth Overall Top 200 Genes 3.919E-4 4.202E-3 2.487E-2
8.151E-2
 2 138
19 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Overall Top 200 Genes 4.090E-4 4.202E-3 2.487E-2
8.508E-2
 2 141
20 Kidney10XCellRanger Six2TGC P0 Eryth Eryth Top 200 Kidney10XCellRanger Six2TGC P0 Eryth Eryth Top 200 4.266E-4 4.202E-3 2.487E-2
8.873E-2
 2 144
21 Kidney10XCellRanger Six2TGC P0 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2TGC P0 Eryth Eryth Overall Top 200 Genes 4.266E-4 4.202E-3 2.487E-2
8.873E-2
 2 144
22 Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Erythrocyte (ER) Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Erythrocyte (ER) Fetal, Development 4.445E-4 4.202E-3 2.487E-2
9.245E-2
 2 147
23 Kidney10XCellRanger Six2TGC E14 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2TGC E14 Eryth Eryth Overall Top 200 Genes 4.876E-4 4.226E-3 2.501E-2
1.014E-1
 2 154
24 Kidney10XCellRanger Six2TGC E14 Eryth Eryth Top 200 Kidney10XCellRanger Six2TGC E14 Eryth Eryth Top 200 4.876E-4 4.226E-3 2.501E-2
1.014E-1
 2 154
25 Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C11-KC7 Top 200 Genes Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C11-KC7 Top 200 Genes 5.394E-4 4.315E-3 2.553E-2
1.122E-1
 2 162
26 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 200 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 5.394E-4 4.315E-3 2.553E-2
1.122E-1
 2 162
27 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C7-KC1 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C7-KC1 Top 200 Genes 6.148E-4 4.736E-3 2.802E-2
1.279E-1
 2 173
28 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal-Cortex Wilms F-U/Kidney Normal-Cortex Wilms F16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal-Cortex Wilms F-U/Kidney Normal-Cortex Wilms F16 Adult, Development, and Cancer types 7.330E-4 5.425E-3 3.210E-2
1.525E-1
 2 189
29 Erythrocyte (ER) Erythrocyte (ER) 7.563E-4 5.425E-3 3.210E-2
1.573E-1
 2 192
30 Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C12-KC7 Top 200 Genes Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C12-KC7 Top 200 Genes 9.037E-4 6.121E-3 3.622E-2
1.880E-1
 2 210
31 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C6-KC1 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C6-KC1 Top 200 Genes 9.123E-4 6.121E-3 3.622E-2
1.897E-1
 2 211
32 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C1-KC1 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C1-KC1 Top 200 Genes 9.911E-4 6.442E-3 3.812E-2
2.062E-1
 2 220
33 Kidney10XCellRanger Six2KI E14 Eryth Eryth Top 200 Kidney10XCellRanger Six2KI E14 Eryth Eryth Top 200 1.073E-3 6.764E-3 4.002E-2
2.232E-1
 2 229
34 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 500 k2 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.237E-3 7.567E-3 4.477E-2
2.573E-1
 2 246
35 Lungmap Mouse Lung PND3 X Subtype X-A Lungmap Mouse Lung PND3 X Subtype X-A Lungmap CCHMC 1.423E-3 8.454E-3
5.002E-2
2.959E-1
 2 264
36 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp Oligodendrocyte.oligodendrocytes.Mbp Subtype Oligodendrocyte.oligodendrocytes.Mbp.Tfr Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp Oligodendrocyte.oligodendrocytes.Mbp Subtype Oligodendrocyte.oligodendrocytes.Mbp.Tfr Top 200 Genes BrainMap 1.476E-3 8.530E-3
5.047E-2
3.071E-1
 2 269
37 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Top 200 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Top 200 1.892E-3 1.064E-2
6.295E-2
3.936E-1
 2 305
38 Facebase ST1 e10.5 NeuroEpith FlankLateral 500 5 e10.5 NeuroEpith FlankLateral top-relative-expression-ranked 500 5 FaceBase_ST1 2.211E-3 1.200E-2
7.103E-2
4.599E-1
 2 330
39 gudmap kidney adult JuxtaGlom Ren1 k2 1000 kidney adult JuxtaGlom Ren1 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.251E-3 1.200E-2
7.103E-2
4.681E-1
 2 333
40 Kidney10XCellRanger Six2TGC E14 Stroma Stroma Subtype E14-Six2TGC-Stroma2-C6-KC3 Top 200 Genes Kidney10XCellRanger Six2TGC E14 Stroma Stroma Subtype E14-Six2TGC-Stroma2-C6-KC3 Top 200 Genes 2.400E-3 1.248E-2
7.383E-2
4.991E-1
 2 344
41 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 1000 k4 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.904E-3 1.436E-2
8.497E-2
6.041E-1
 2 379
42 gudmap developingGonad e16.5 ovary 500 DevelopingGonad e16.5 ovary emap-9563 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.057E-3 1.436E-2
8.497E-2
6.358E-1
 2 389
43 gudmap kidney single cell adult RenalCortexMixed Scamp k4 500 kidney single cell adult RenalCortexMixed StemCellamp k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.119E-3 1.436E-2
8.497E-2
6.487E-1
 2 393
44 Sample Type by Project: Shred 1/TCGA-Bladder/Urothelial Carcinoma/Papillary Muscle Invasive Urothelial Carcinoma/1/3 Sample Type by Project: Shred 1/TCGA-Bladder/Urothelial Carcinoma/Papillary Muscle Invasive Urothelial Carcinoma/1/3 TCGA-Bladder 3.203E-3 1.436E-2
8.497E-2
6.662E-1
 1 14
45 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp Oligodendrocyte.oligodendrocytes.Mbp Top 200 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp Oligodendrocyte.oligodendrocytes.Mbp Top 200 BrainMap 3.213E-3 1.436E-2
8.497E-2
6.683E-1
 2 399
46 GSM854317 500 Myeloid Cells, MF.BM, B220neg CD3neg Ly-6C/Glo CD115int F4/80+, Bone marrow, avg-3 Immgen.org, GSE15907 3.245E-3 1.436E-2
8.497E-2
6.749E-1
 2 401
47 GSM791108 500 Stem Cells, SC.MEP.BM, Lineage- Kit+ Sca1- CD34- FcgR-/low, Bone marrow, avg-2 Immgen.org, GSE15907 3.245E-3 1.436E-2
8.497E-2
6.749E-1
 2 401
48 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 500 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.325E-3 1.441E-2
8.525E-2
6.916E-1
 2 406
49 Facebase ST1 e9.5 MaxilArch 500 e9.5 MaxilArch top-relative-expression-ranked 500 FaceBase_ST1 3.876E-3 1.645E-2
9.736E-2
8.063E-1
 2 439
50 PP HSC 2500 K1 PP HSC top-relative-expression-ranked 2500 k-means-cluster#1 PCBC 4.016E-3 1.671E-2
9.886E-2
8.353E-1
 2 447
Show 45 more annotations

15: Computational [Display Chart] 4 input genes in category / 19 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M14349 GNF2 PCAF Neighborhood of PCAF MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.691E-7 3.213E-6 1.140E-5 3.213E-6 3 36
2 M9058 GNF2 BNIP3L Neighborhood of BNIP3L MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.184E-6 4.328E-6 1.536E-5 2.250E-5 3 68
3 M19158 GNF2 RAD23A Neighborhood of RAD23A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.238E-6 4.328E-6 1.536E-5 2.352E-5 3 69
4 M19762 GNF2 TAL1 Neighborhood of TAL1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.469E-6 4.328E-6 1.536E-5 2.791E-5 3 73
5 M11900 GNF2 ANK1 Neighborhood of ANK1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.531E-6 4.328E-6 1.536E-5 2.909E-5 3 74
6 M5633 GNF2 SPTB Neighborhood of SPTB MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.531E-6 4.328E-6 1.536E-5 2.909E-5 3 74
7 M1670 GNF2 MAP2K3 Neighborhood of MAP2K3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.595E-6 4.328E-6 1.536E-5 3.030E-5 3 75
8 M13711 GNF2 SPTA1 Neighborhood of SPTA1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.014E-6 4.783E-6 1.697E-5 3.826E-5 3 81
9 M17504 MODULE 539 Genes in the cancer module 539. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.427E-5 3.012E-5 1.069E-4 2.711E-4 2 16
10 M7470 GNF2 CDC27 Neighborhood of CDC27 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.092E-4 3.975E-4 1.410E-3 3.975E-3 2 60
11 M2266 GNF2 SPRR1B Neighborhood of SPRR1B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.927E-3 1.715E-2
6.083E-2
1.886E-1
 1 25
12 M10458 GNF2 PRDX2 Neighborhood of PRDX2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.230E-2 1.947E-2
6.909E-2
2.337E-1
 1 31
13 M14481 MODULE 284 Genes in the cancer module 284. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.782E-2 2.604E-2
9.238E-2
3.385E-1
 1 45
Show 8 more annotations

16: MicroRNA [Display Chart] 5 input genes in category / 78 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-372-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.037E-4 4.149E-3 2.050E-2 1.589E-2 2 328
2 hsa-miR-371a-5p:Functional MTI Functional MTI miRTarbase 2.253E-4 4.149E-3 2.050E-2 1.757E-2 2 345
3 hsa-miR-373-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.604E-4 4.149E-3 2.050E-2 2.031E-2 2 371
4 hsa-miR-371b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.618E-4 4.149E-3 2.050E-2 2.042E-2 2 372
5 hsa-miR-616-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.660E-4 4.149E-3 2.050E-2 2.075E-2 2 375
6 hsa-miR-6740-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.422E-3 2.870E-2
1.418E-1
3.449E-1
 1 64
7 hsa-miR-1228*:mirSVR highEffct hsa-miR-1228*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.905E-3 2.870E-2
1.418E-1
3.826E-1
 1 71
8 AATGGAG,MIR-136:MSigDB AATGGAG,MIR-136:MSigDB MSigDB 4.974E-3 2.870E-2
1.418E-1
3.879E-1
 1 72
9 hsa-miR-7843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.974E-3 2.870E-2
1.418E-1
3.879E-1
 1 72
10 hsa-miR-6748-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.042E-3 2.870E-2
1.418E-1
3.933E-1
 1 73
11 hsa-miR-1911-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 2.870E-2
1.418E-1
4.041E-1
 1 75
12 hsa-miR-6830-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 2.870E-2
1.418E-1
4.041E-1
 1 75
13 hsa-miR-886-3p:mirSVR highEffct hsa-miR-886-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.869E-3 2.870E-2
1.418E-1
4.578E-1
 1 85
14 CCAGGGG,MIR-331:MSigDB CCAGGGG,MIR-331:MSigDB MSigDB 6.420E-3 2.870E-2
1.418E-1
5.008E-1
 1 93
15 hsa-miR-4426:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 2.870E-2
1.418E-1
5.330E-1
 1 99
16 hsa-miR-4662b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 2.870E-2
1.418E-1
5.330E-1
 1 99
17 hsa-miR-4647:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 2.870E-2
1.418E-1
5.330E-1
 1 99
18 hsa-miR-4733-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.109E-3 2.870E-2
1.418E-1
5.545E-1
 1 103
19 hsa-miR-676-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.590E-3 2.870E-2
1.418E-1
5.921E-1
 1 110
20 hsa-miR-4786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.659E-3 2.870E-2
1.418E-1
5.974E-1
 1 111
21 hsa-miR-383-5p:Functional MTI Functional MTI miRTarbase 7.728E-3 2.870E-2
1.418E-1
6.028E-1
 1 112
22 hsa-miR-127-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.278E-3 2.894E-2
1.430E-1
6.457E-1
 1 120
23 hsa-miR-4451:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.828E-3 2.894E-2
1.430E-1
6.886E-1
 1 128
24 hsa-miR-1268:mirSVR highEffct hsa-miR-1268:mirSVR nonconserved highEffect-0.5 MicroRNA.org 9.172E-3 2.894E-2
1.430E-1
7.154E-1
 1 133
25 hsa-miR-382-5p:TargetScan hsa-miR-382-5p TargetScan 1.020E-2 2.894E-2
1.430E-1
7.957E-1
 1 148
26 hsa-miR-6513-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.137E-2 2.894E-2
1.430E-1
8.867E-1
 1 165
27 hsa-miR-5197-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.137E-2 2.894E-2
1.430E-1
8.867E-1
 1 165
28 hsa-miR-466:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.164E-2 2.894E-2
1.430E-1
9.081E-1
 1 169
29 hsa-miR-4421:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.199E-2 2.894E-2
1.430E-1
9.349E-1
 1 174
30 hsa-miR-5699-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.199E-2 2.894E-2
1.430E-1
9.349E-1
 1 174
31 hsa-miR-4643:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.219E-2 2.894E-2
1.430E-1
9.509E-1
 1 177
32 hsa-miR-585:mirSVR lowEffct hsa-miR-585:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 1.260E-2 2.894E-2
1.430E-1
9.830E-1
 1 183
33 hsa-miR-3927-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.267E-2 2.894E-2
1.430E-1
9.883E-1
 1 184
34 hsa-miR-6831-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.281E-2 2.894E-2
1.430E-1
9.990E-1
 1 186
35 hsa-miR-4465:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.308E-2 2.894E-2
1.430E-1
1.000E0
 1 190
36 hsa-miR-1297:Functional MTI Functional MTI miRTarbase 1.336E-2 2.894E-2
1.430E-1
1.000E0
 1 194
37 hsa-miR-3663-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.493E-2 2.912E-2
1.439E-1
1.000E0
 1 217
38 hsa-miR-6500-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.493E-2 2.912E-2
1.439E-1
1.000E0
 1 217
39 hsa-miR-6848-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.548E-2 2.912E-2
1.439E-1
1.000E0
 1 225
40 hsa-miR-6843-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.548E-2 2.912E-2
1.439E-1
1.000E0
 1 225
41 hsa-miR-6131:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.554E-2 2.912E-2
1.439E-1
1.000E0
 1 226
42 hsa-miR-3614-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.568E-2 2.912E-2
1.439E-1
1.000E0
 1 228
43 hsa-miR-4789-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.746E-2 3.167E-2
1.564E-1
1.000E0
 1 254
44 hsa-miR-889:PITA hsa-miR-889:PITA TOP PITA 1.923E-2 3.330E-2
1.645E-1
1.000E0
 1 280
45 hsa-miR-6790-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.937E-2 3.330E-2
1.645E-1
1.000E0
 1 282
46 hsa-miR-6821-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.964E-2 3.330E-2
1.645E-1
1.000E0
 1 286
47 hsa-miR-4789-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.012E-2 3.338E-2
1.649E-1
1.000E0
 1 293
48 hsa-miR-4500:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.141E-2 3.339E-2
1.650E-1
1.000E0
 1 312
49 hsa-miR-4458:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.141E-2 3.339E-2
1.650E-1
1.000E0
 1 312
50 hsa-miR-1233:mirSVR highEffct hsa-miR-1233:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.277E-2 3.339E-2
1.650E-1
1.000E0
 1 332
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 721 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000067050 rhodizonic acid Stitch 2.153E-11 1.552E-8 1.111E-7 1.552E-8 5 170
2 CID000002825 cocaethylene Stitch 4.788E-10 1.726E-7 1.236E-6 3.452E-7 4 73
3 ctd:D000641 Ammonia CTD 8.684E-8 2.087E-5 1.494E-4 6.261E-5 3 48
4 CID005288461 AC1NRBKB Stitch 1.897E-7 3.420E-5 2.448E-4 1.368E-4 3 62
5 CID000123895 N(omega)-hydroxy-L-arginine Stitch 2.990E-7 3.904E-5 2.795E-4 2.156E-4 3 72
6 CID000074537 1, 3-diallylurea Stitch 3.249E-7 3.904E-5 2.795E-4 2.343E-4 3 74
7 CID000001855 DHBT Stitch 1.403E-6 1.445E-4 1.035E-3 1.012E-3 3 120
8 CID005287861 AC1NRAG8 Stitch 3.485E-6 3.141E-4 2.248E-3 2.513E-3 2 14
9 CID000006329 methylamine Stitch 8.929E-6 7.153E-4 5.121E-3 6.438E-3 3 222
10 CID000002735 vitamin D3 Stitch 1.733E-5 1.249E-3 8.944E-3 1.249E-2 3 277
11 CID000123421 methyldiazene Stitch 2.274E-5 1.491E-3 1.067E-2 1.640E-2 2 35
12 CID000107720 indoxacarb Stitch 4.490E-5 2.698E-3 1.931E-2 3.237E-2 2 49
13 CID000004777 NSC139075 Stitch 1.203E-4 6.673E-3 4.777E-2
8.675E-2
 2 80
14 ctd:D006851 Hydrochloric Acid CTD 1.662E-4 8.307E-3
5.946E-2
1.198E-1
 2 94
15 CID000000011 1,2-dichloroethane Stitch 1.844E-4 8.307E-3
5.946E-2
1.330E-1
 2 99
16 CID000001182 DL-valine Stitch 2.074E-4 8.307E-3
5.946E-2
1.496E-1
 2 105
17 CID000132880 RHC 3288 Stitch 2.189E-4 8.307E-3
5.946E-2
1.578E-1
 1 1
18 CID000195267 BBR 2160 Stitch 2.189E-4 8.307E-3
5.946E-2
1.578E-1
 1 1
19 CID000040026 bucainide Stitch 2.189E-4 8.307E-3
5.946E-2
1.578E-1
 1 1
20 CID000088068 methyl m-oxybenzoate Stitch 4.378E-4 1.338E-2
9.579E-2
3.156E-1
 1 2
21 CID000130934 Y-27152 Stitch 4.378E-4 1.338E-2
9.579E-2
3.156E-1
 1 2
22 CID000001198 isocitrate Stitch 4.573E-4 1.338E-2
9.579E-2
3.297E-1
 2 156
23 CID004369084 PNU-107859 Stitch 5.684E-4 1.338E-2
9.579E-2
4.098E-1
 2 174
24 CID000445801 1ga8 Stitch 6.352E-4 1.338E-2
9.579E-2
4.580E-1
 2 184
25 CID000025517 NH4Cl Stitch 6.352E-4 1.338E-2
9.579E-2
4.580E-1
 2 184
26 CID000122073 Calbren Stitch 6.566E-4 1.338E-2
9.579E-2
4.734E-1
 1 3
27 CID000071143 MDL-899 Stitch 6.566E-4 1.338E-2
9.579E-2
4.734E-1
 1 3
28 CID005317628 AC1NSVVN Stitch 6.566E-4 1.338E-2
9.579E-2
4.734E-1
 1 3
29 3850 UP Methyl benzethonium chloride [25155-18-4]; Up 200; 8.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.985E-4 1.338E-2
9.579E-2
5.036E-1
 2 193
30 CID000000640 NSC23615 Stitch 6.985E-4 1.338E-2
9.579E-2
5.036E-1
 2 193
31 4441 UP chlorpromazine hydrochloride; Up 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP Up 7.057E-4 1.338E-2
9.579E-2
5.088E-1
 2 194
32 4382 UP CP-320650-01 [172079-28-6]; Up 200; 1uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.130E-4 1.338E-2
9.579E-2
5.140E-1
 2 195
33 3642 UP Betonicine [515-25-3]; Up 200; 25.2uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.130E-4 1.338E-2
9.579E-2
5.140E-1
 2 195
34 4372 UP Methimazole [60-56-0]; Up 200; 35uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.203E-4 1.338E-2
9.579E-2
5.193E-1
 2 196
35 5577 UP chlorpromazine hydrochloride; Up 200; 1uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.203E-4 1.338E-2
9.579E-2
5.193E-1
 2 196
36 4391 UP Sparteine (-) [90-39-1]; Up 200; 17uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.276E-4 1.338E-2
9.579E-2
5.246E-1
 2 197
37 2248 UP Tranexamic acid [1197-18-8]; Up 200; 25.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.276E-4 1.338E-2
9.579E-2
5.246E-1
 2 197
38 3899 UP Lithocholic acid [434-13-9]; Up 200; 10.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.349E-4 1.338E-2
9.579E-2
5.299E-1
 2 198
39 3966 UP 0317956-0000 [391210-11-0]; Up 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP Up 7.423E-4 1.338E-2
9.579E-2
5.352E-1
 2 199
40 6401 DN F0447-0125; Down 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP Down 7.423E-4 1.338E-2
9.579E-2
5.352E-1
 2 199
41 CID000054550 CHBZ Stitch 8.754E-4 1.434E-2
1.027E-1
6.312E-1
 1 4
42 CID000131737 RHC 3414 Stitch 8.754E-4 1.434E-2
1.027E-1
6.312E-1
 1 4
43 CID000435807 AC1L909B Stitch 8.754E-4 1.434E-2
1.027E-1
6.312E-1
 1 4
44 CID000054684 AC1L1HJI Stitch 8.754E-4 1.434E-2
1.027E-1
6.312E-1
 1 4
45 CID000033508 ADCMC Stitch 1.094E-3 1.678E-2
1.202E-1
7.889E-1
 1 5
46 CID005473883 AC1NV8X5 Stitch 1.094E-3 1.678E-2
1.202E-1
7.889E-1
 1 5
47 CID000040520 barnon Stitch 1.094E-3 1.678E-2
1.202E-1
7.889E-1
 1 5
48 CID000024085 HgCl2 Stitch 1.291E-3 1.893E-2
1.355E-1
9.307E-1
 2 263
49 CID003081108 Du 1777 Stitch 1.313E-3 1.893E-2
1.355E-1
9.466E-1
 1 6
50 CID000015232 benzathine penicillin Stitch 1.313E-3 1.893E-2
1.355E-1
9.466E-1
 1 6
Show 45 more annotations

18: Disease [Display Chart] 4 input genes in category / 42 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0272052 Rh Deficiency Syndrome DisGeNET Curated 5.641E-12 2.369E-10 1.025E-9 2.369E-10 3 3
2 C0158962 Hemolytic disease of fetus OR newborn due to RhD isoimmunization DisGeNET BeFree 4.570E-8 9.597E-7 4.152E-6 1.919E-6 2 2
3 C0002881 Anemia, Hemolytic, Congenital DisGeNET Curated 3.014E-6 4.219E-5 1.826E-4 1.266E-4 2 12
4 C0014761 Erythroblastosis, Fetal DisGeNET BeFree 4.793E-6 5.033E-5 2.178E-4 2.013E-4 2 15
5 C0948201 Alloimmunisation DisGeNET BeFree 6.207E-6 5.214E-5 2.256E-4 2.607E-4 2 17
6 cv:C1862200 BLOOD GROUP--RHESUS SYSTEM E POLYPEPTIDE Clinical Variations 2.468E-4 1.037E-3 4.486E-3 1.037E-2 1 1
7 OMIN:268150 RH-NULL, REGULATOR TYPE; RHN OMIM 2.468E-4 1.037E-3 4.486E-3 1.037E-2 1 1
8 OMIN:111690 BLOOD GROUP--RHESUS SYSTEM E POLYPEPTIDE; RHE OMIM 2.468E-4 1.037E-3 4.486E-3 1.037E-2 1 1
9 C1849387 Rh-Null, Regulator Type DisGeNET Curated 2.468E-4 1.037E-3 4.486E-3 1.037E-2 1 1
10 cv:C1849387 Rh-null, regulator type Clinical Variations 2.468E-4 1.037E-3 4.486E-3 1.037E-2 1 1
11 C4025593 Increased intracellular sodium DisGeNET Curated 4.936E-4 1.885E-3 8.155E-3 2.073E-2 1 2
12 C0002895 Anemia, Sickle Cell DisGeNET Curated 9.765E-4 3.189E-3 1.380E-2 4.101E-2 2 209
13 C1849478 Increased red cell osmotic fragility DisGeNET Curated 9.871E-4 3.189E-3 1.380E-2 4.146E-2 1 4
14 C0854914 bilateral retinoblastoma DisGeNET BeFree 1.234E-3 3.657E-3 1.582E-2
5.182E-2
 1 5
15 C0677598 Stomatocytosis Result DisGeNET Curated 1.480E-3 3.657E-3 1.582E-2
6.217E-2
 1 6
16 C1263988 Hemolytic disorder DisGeNET BeFree 1.480E-3 3.657E-3 1.582E-2
6.217E-2
 1 6
17 C1861455 STOMATOCYTOSIS I DisGeNET Curated 1.480E-3 3.657E-3 1.582E-2
6.217E-2
 1 6
18 C1849452 SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 2 (disorder) DisGeNET BeFree 1.973E-3 4.605E-3 1.992E-2
8.288E-2
 1 8
19 C0268306 Unconjugated hyperbilirubinemia DisGeNET Curated 2.220E-3 4.907E-3 2.123E-2
9.324E-2
 1 9
20 C0311468 Increased bilirubin level (finding) DisGeNET Curated 4.436E-3 9.316E-3 4.031E-2
1.863E-1
 1 18
21 C0206160 Reticulocytosis DisGeNET Curated 4.928E-3 9.856E-3 4.264E-2
2.070E-1
 1 20
22 C0220611 childhood rhabdomyosarcoma DisGeNET BeFree 6.649E-3 1.269E-2
5.492E-2
2.792E-1
 1 27
23 C0035439 Rheumatic Heart Disease DisGeNET BeFree 9.103E-3 1.662E-2
7.192E-2
3.823E-1
 1 37
24 C0272286 Thrombocytopenia due to platelet alloimmunization DisGeNET BeFree 1.131E-2 1.979E-2
8.562E-2
4.749E-1
 1 46
25 C1266184 Atypical teratoid/rhabdoid tumor DisGeNET BeFree 1.180E-2 1.982E-2
8.575E-2
4.955E-1
 1 48
26 C0206743 Rhabdoid Tumor DisGeNET Curated 1.595E-2 2.575E-2
1.114E-1
6.699E-1
 1 65
27 C0206655 Alveolar rhabdomyosarcoma DisGeNET Curated 1.668E-2 2.575E-2
1.114E-1
7.006E-1
 1 68
28 C0242584 Autoimmune thrombocytopenia DisGeNET Curated 1.717E-2 2.575E-2
1.114E-1
7.211E-1
 1 70
29 C0002878 Anemia, Hemolytic DisGeNET Curated 2.785E-2 4.033E-2
1.745E-1
1.000E0
 1 114
30 C0747845 early pregnancy DisGeNET BeFree 3.123E-2 4.361E-2
1.887E-1
1.000E0
 1 128
31 C0022346 Icterus DisGeNET Curated 3.219E-2 4.361E-2
1.887E-1
1.000E0
 1 132
Show 26 more annotations