|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
10491391
|
Defective kinesin heavy chain behavior in mouse kinesin light chain mutants.
|
Pubmed
|
2.154E-11
|
5.686E-9
|
3.500E-8
|
5.686E-9
|
3
|
5
|
2
|
19164528
|
Nesprin 4 is an outer nuclear membrane protein that can induce kinesin-mediated cell polarization.
|
Pubmed
|
4.307E-11
|
5.686E-9
|
3.500E-8
|
1.137E-8
|
3
|
6
|
3
|
9624122
|
Two kinesin light chain genes in mice. Identification and characterization of the encoded proteins.
|
Pubmed
|
1.809E-10
|
1.592E-8
|
9.797E-8
|
4.775E-8
|
3
|
9
|
4
|
16018997
|
The ciliary rootlet interacts with kinesin light chains and may provide a scaffold for kinesin-1 vesicular cargos.
|
Pubmed
|
4.736E-10
|
2.501E-8
|
1.539E-7
|
1.250E-7
|
3
|
12
|
5
|
16301330
|
Coordinated transport of phosphorylated amyloid-beta precursor protein and c-Jun NH2-terminal kinase-interacting protein-1.
|
Pubmed
|
4.736E-10
|
2.501E-8
|
1.539E-7
|
1.250E-7
|
3
|
12
|
6
|
19773350
|
Role of kinesin light chain-2 of kinesin-1 in the traffic of Na,K-ATPase-containing vesicles in alveolar epithelial cells.
|
Pubmed
|
2.057E-8
|
9.049E-7
|
5.570E-6
|
5.430E-6
|
2
|
2
|
7
|
15324660
|
Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.
|
Pubmed
|
2.927E-8
|
1.104E-6
|
6.794E-6
|
7.726E-6
|
4
|
256
|
8
|
8786141
|
Sequence analysis of the ERCC2 gene regions in human, mouse, and hamster reveals three linked genes.
|
Pubmed
|
6.170E-8
|
1.810E-6
|
1.114E-5
|
1.629E-5
|
2
|
3
|
9
|
25855459
|
Repeated ER-endosome contacts promote endosome translocation and neurite outgrowth.
|
Pubmed
|
6.170E-8
|
1.810E-6
|
1.114E-5
|
1.629E-5
|
2
|
3
|
10
|
19861499
|
Cayman ataxia protein caytaxin is transported by kinesin along neurites through binding to kinesin light chains.
|
Pubmed
|
1.234E-7
|
3.257E-6
|
2.005E-5
|
3.257E-5
|
2
|
4
|
11
|
21750526
|
Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility.
|
Pubmed
|
2.056E-7
|
4.935E-6
|
3.038E-5
|
5.428E-5
|
2
|
5
|
12
|
17979178
|
A novel tandem affinity purification strategy for the efficient isolation and characterisation of native protein complexes.
|
Pubmed
|
2.272E-7
|
4.998E-6
|
3.076E-5
|
5.998E-5
|
3
|
87
|
13
|
21335237
|
Stable kinesin and dynein assemblies drive the axonal transport of mammalian prion protein vesicles.
|
Pubmed
|
4.318E-7
|
8.768E-6
|
5.397E-5
|
1.140E-4
|
2
|
7
|
14
|
11969417
|
Phosphorylation-dependent interaction of kinesin light chain 2 and the 14-3-3 protein.
|
Pubmed
|
7.400E-7
|
1.396E-5
|
8.589E-5
|
1.954E-4
|
2
|
9
|
15
|
19825938
|
Dynein and kinesin regulate stress-granule and P-body dynamics.
|
Pubmed
|
9.250E-7
|
1.526E-5
|
9.394E-5
|
2.442E-4
|
2
|
10
|
16
|
21915095
|
A kinesin-1 binding motif in vaccinia virus that is widespread throughout the human genome.
|
Pubmed
|
9.250E-7
|
1.526E-5
|
9.394E-5
|
2.442E-4
|
2
|
10
|
17
|
28625565
|
The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base.
|
Pubmed
|
1.356E-6
|
2.106E-5
|
1.297E-4
|
3.581E-4
|
2
|
12
|
18
|
15161933
|
Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.
|
Pubmed
|
1.626E-6
|
2.385E-5
|
1.468E-4
|
4.294E-4
|
3
|
167
|
19
|
19765186
|
Identification of novel spartin-interactors shows spartin is a multifunctional protein.
|
Pubmed
|
3.513E-6
|
4.416E-5
|
2.718E-4
|
9.274E-4
|
2
|
19
|
20
|
24421332
|
The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.
|
Pubmed
|
3.513E-6
|
4.416E-5
|
2.718E-4
|
9.274E-4
|
2
|
19
|
21
|
15529118
|
Synapsin and synaptic vesicle protein expression during embryonic and post-natal lens fiber cell differentiation.
|
Pubmed
|
3.513E-6
|
4.416E-5
|
2.718E-4
|
9.274E-4
|
2
|
19
|
22
|
22261722
|
Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture.
|
Pubmed
|
9.544E-6
|
1.145E-4
|
7.049E-4
|
2.520E-3
|
2
|
31
|
23
|
20114047
|
Dynamin-1 co-associates with native mouse brain BKCa channels: proteomics analysis of synaptic protein complexes.
|
Pubmed
|
2.613E-5
|
3.000E-4
|
1.846E-3
|
6.899E-3
|
2
|
51
|
24
|
15778465
|
Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.
|
Pubmed
|
8.743E-5
|
6.284E-4
|
3.868E-3
|
2.308E-2
|
2
|
93
|
25
|
25902401
|
Examining kinesin processivity within a general gating framework.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
26
|
11130971
|
Genomic organization and mapping of mouse CDV (carnitine deficiency-associated gene expressed in ventricle)-1 and its related CDV-1R gene.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
27
|
8606779
|
Crystal structure of the kinesin motor domain reveals a structural similarity to myosin.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
28
|
30015159
|
Oncogenic Function of a KIF5B-MET Fusion Variant in Non-Small Cell Lung Cancer.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
29
|
23402760
|
Dissect Kif5b in nuclear positioning during myogenesis: the light chain binding domain and the autoinhibitory peptide are both indispensable.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
30
|
24072715
|
Motor domain phosphorylation modulates kinesin-1 transport.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
31
|
25450690
|
Kinesin-1 translocation: Surprising differences between bovine brain and MCF7-derived microtubules.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
32
|
25676575
|
Identification of tail binding effect of kinesin-1 using an elastic network model.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
33
|
21925109
|
Kinesin-1-mediated capsid disassembly and disruption of the nuclear pore complex promote virus infection.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
34
|
10210276
|
Catecholamine metabolism inhibitors and receptor blockades only partially suppress cardiac hypertrophy of juvenile visceral steatosis mice with systemic carnitine deficiency.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
35
|
25537000
|
Decrypting the structural, dynamic, and energetic basis of a monomeric kinesin interacting with a tubulin dimer in three ATPase states by all-atom molecular dynamics simulation.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
36
|
22198464
|
A metal switch for controlling the activity of molecular motor proteins.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
37
|
28284467
|
Moonlighting Motors: Kinesin, Dynein, and Cell Polarity.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
38
|
17925227
|
Polarization-dependent selective transport to the apical membrane by KIF5B in MDCK cells.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
39
|
28460050
|
IFT81 as a Candidate Gene for Nonsyndromic Retinal Degeneration.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
40
|
20152113
|
Delivery of GABAARs to synapses is mediated by HAP1-KIF5 and disrupted by mutant huntingtin.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
41
|
26884162
|
The light chains of kinesin-1 are autoinhibited.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
42
|
19242560
|
Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
43
|
18817524
|
Kinesin-1 (uKHC/KIF5B) is required for bidirectional motility of ER exit sites and efficient ER-to-Golgi transport.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
44
|
25818289
|
Kinesin's front head is gated by the backward orientation of its neck linker.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
45
|
22561200
|
KLC3 is involved in sperm tail midpiece formation and sperm function.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
46
|
19348763
|
The Kinesin-1 tail conformationally restricts the nucleotide pocket.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
47
|
29229862
|
A small-molecule activator of kinesin-1 drives remodeling of the microtubule network.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
48
|
28242773
|
Adipose-specific deletion of Kif5b exacerbates obesity and insulin resistance in a mouse model of diet-induced obesity.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
49
|
18579780
|
The kinesin-1 motor protein is regulated by a direct interaction of its head and tail.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|
50
|
20071331
|
Microtubule-associated protein-like binding of the kinesin-1 tail to microtubules.
|
Pubmed
|
1.571E-4
|
6.284E-4
|
3.868E-3
|
4.147E-2
|
1
|
1
|