Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc324_14, positive side

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1: GO: Molecular Function [Display Chart] 14 input genes in category / 60 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0003713 transcription coactivator activity 3.156E-20 1.894E-18 8.862E-18 1.894E-18 12 310
2 GO:0031491 nucleosome binding 9.848E-16 2.954E-14 1.383E-13 5.909E-14 7 45
3 GO:0031492 nucleosomal DNA binding 3.016E-14 6.032E-13 2.823E-12 1.810E-12 6 30
4 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding 7.165E-12 1.075E-10 5.030E-10 4.299E-10 6 71
5 GO:0031490 chromatin DNA binding 2.177E-11 2.612E-10 1.222E-9 1.306E-9 6 85
6 GO:0001158 enhancer sequence-specific DNA binding 3.783E-11 3.783E-10 1.770E-9 2.270E-9 6 93
7 GO:0035326 enhancer binding 8.425E-11 7.222E-10 3.380E-9 5.055E-9 6 106
8 GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding 4.095E-9 3.071E-8 1.437E-7 2.457E-7 7 379
9 GO:0000987 proximal promoter sequence-specific DNA binding 5.746E-9 3.831E-8 1.793E-7 3.448E-7 7 398
10 GO:0047485 protein N-terminus binding 8.314E-5 4.988E-4 2.334E-3 4.988E-3 3 117
11 GO:0016922 nuclear receptor binding 1.553E-4 8.469E-4 3.963E-3 9.316E-3 2 25
12 GO:0004386 helicase activity 2.599E-4 1.300E-3 6.082E-3 1.560E-2 3 172
13 GO:0008094 DNA-dependent ATPase activity 2.150E-3 9.925E-3 4.645E-2
1.290E-1
 2 93
14 GO:0016887 ATPase activity 4.056E-3 1.738E-2
8.135E-2
2.434E-1
 3 446
15 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding 5.987E-3 2.113E-2
9.889E-2
3.592E-1
 1 8
16 GO:0030957 Tat protein binding 5.987E-3 2.113E-2
9.889E-2
3.592E-1
 1 8
17 GO:0001164 RNA polymerase I CORE element sequence-specific DNA binding 5.987E-3 2.113E-2
9.889E-2
3.592E-1
 1 8
18 GO:0001013 RNA polymerase I regulatory region DNA binding 6.733E-3 2.244E-2
1.050E-1
4.040E-1
 1 9
19 GO:0042393 histone binding 7.802E-3 2.464E-2
1.153E-1
4.681E-1
 2 180
20 GO:0070182 DNA polymerase binding 9.712E-3 2.914E-2
1.364E-1
5.827E-1
 1 13
21 GO:0070577 lysine-acetylated histone binding 1.268E-2 3.624E-2
1.696E-1
7.610E-1
 1 17
Show 16 more annotations

2: GO: Biological Process [Display Chart] 14 input genes in category / 319 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006338 chromatin remodeling 6.258E-21 1.996E-18 1.266E-17 1.996E-18 11 164
2 GO:0032986 protein-DNA complex disassembly 7.068E-19 7.516E-17 4.768E-16 2.255E-16 7 18
3 GO:0006337 nucleosome disassembly 7.068E-19 7.516E-17 4.768E-16 2.255E-16 7 18
4 GO:0031498 chromatin disassembly 1.721E-18 1.372E-16 8.705E-16 5.489E-16 7 20
5 GO:0006333 chromatin assembly or disassembly 1.722E-15 1.098E-13 6.969E-13 5.492E-13 9 188
6 GO:0043044 ATP-dependent chromatin remodeling 4.326E-14 2.300E-12 1.459E-11 1.380E-11 7 75
7 GO:0034728 nucleosome organization 1.228E-13 5.597E-12 3.551E-11 3.918E-11 8 171
8 GO:0071824 protein-DNA complex subunit organization 2.817E-12 1.123E-10 7.125E-10 8.985E-10 8 252
9 GO:0032984 protein-containing complex disassembly 4.808E-10 1.704E-8 1.081E-7 1.534E-7 7 278
10 GO:0048096 chromatin-mediated maintenance of transcription 5.561E-8 1.774E-6 1.125E-5 1.774E-5 3 11
11 GO:0035887 aortic smooth muscle cell differentiation 1.574E-6 4.564E-5 2.895E-4 5.020E-4 2 3
12 GO:0045815 positive regulation of gene expression, epigenetic 2.787E-5 7.410E-4 4.701E-3 8.892E-3 3 81
13 GO:0040029 regulation of gene expression, epigenetic 3.586E-5 8.799E-4 5.582E-3 1.144E-2 4 265
14 GO:0035886 vascular smooth muscle cell differentiation 1.688E-4 3.846E-3 2.440E-2
5.385E-2
 2 26
15 GO:0006323 DNA packaging 4.438E-4 9.437E-3
5.987E-2
1.416E-1
 3 206
16 GO:0042766 nucleosome mobilization 7.518E-4 1.499E-2
9.508E-2
2.398E-1
 1 1
17 GO:0051145 smooth muscle cell differentiation 8.762E-4 1.644E-2
1.043E-1
2.795E-1
 2 59
18 GO:0003407 neural retina development 9.672E-4 1.714E-2
1.087E-1
3.085E-1
 2 62
19 GO:0030521 androgen receptor signaling pathway 1.062E-3 1.784E-2
1.132E-1
3.389E-1
 2 65
20 GO:0071103 DNA conformation change 1.139E-3 1.817E-2
1.153E-1
3.634E-1
 3 285
21 GO:0043010 camera-type eye development 1.875E-3 2.765E-2
1.754E-1
5.981E-1
 3 339
22 GO:1902661 positive regulation of glucose mediated signaling pathway 2.254E-3 2.765E-2
1.754E-1
7.189E-1
 1 3
23 GO:0003408 optic cup formation involved in camera-type eye development 2.254E-3 2.765E-2
1.754E-1
7.189E-1
 1 3
24 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment 2.254E-3 2.765E-2
1.754E-1
7.189E-1
 1 3
25 GO:0007403 glial cell fate determination 2.254E-3 2.765E-2
1.754E-1
7.189E-1
 1 3
26 GO:0061626 pharyngeal arch artery morphogenesis 2.254E-3 2.765E-2
1.754E-1
7.189E-1
 1 3
27 GO:0001654 eye development 2.814E-3 2.873E-2
1.823E-1
8.977E-1
 3 391
28 GO:0071684 organism emergence from protective structure 3.004E-3 2.873E-2
1.823E-1
9.582E-1
 1 4
29 GO:0006344 maintenance of chromatin silencing 3.004E-3 2.873E-2
1.823E-1
9.582E-1
 1 4
30 GO:1902659 regulation of glucose mediated signaling pathway 3.004E-3 2.873E-2
1.823E-1
9.582E-1
 1 4
31 GO:0021898 commitment of multipotent stem cells to neuronal lineage in forebrain 3.004E-3 2.873E-2
1.823E-1
9.582E-1
 1 4
32 GO:0001835 blastocyst hatching 3.004E-3 2.873E-2
1.823E-1
9.582E-1
 1 4
33 GO:0035188 hatching 3.004E-3 2.873E-2
1.823E-1
9.582E-1
 1 4
34 GO:0021510 spinal cord development 3.112E-3 2.873E-2
1.823E-1
9.926E-1
 2 112
35 GO:0030900 forebrain development 3.152E-3 2.873E-2
1.823E-1
1.000E0
 3 407
36 GO:0042692 muscle cell differentiation 3.263E-3 2.891E-2
1.834E-1
1.000E0
 3 412
37 GO:0006342 chromatin silencing 3.679E-3 2.920E-2
1.853E-1
1.000E0
 2 122
38 GO:0010255 glucose mediated signaling pathway 3.754E-3 2.920E-2
1.853E-1
1.000E0
 1 5
39 GO:0010182 sugar mediated signaling pathway 3.754E-3 2.920E-2
1.853E-1
1.000E0
 1 5
40 GO:0009757 hexose mediated signaling 3.754E-3 2.920E-2
1.853E-1
1.000E0
 1 5
41 GO:0010424 DNA methylation on cytosine within a CG sequence 3.754E-3 2.920E-2
1.853E-1
1.000E0
 1 5
42 GO:1901838 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I 4.503E-3 3.271E-2
2.075E-1
1.000E0
 1 6
43 GO:0032776 DNA methylation on cytosine 4.503E-3 3.271E-2
2.075E-1
1.000E0
 1 6
44 GO:0030518 intracellular steroid hormone receptor signaling pathway 4.548E-3 3.271E-2
2.075E-1
1.000E0
 2 136
45 GO:0045814 negative regulation of gene expression, epigenetic 4.614E-3 3.271E-2
2.075E-1
1.000E0
 2 137
46 GO:0006334 nucleosome assembly 5.084E-3 3.490E-2
2.214E-1
1.000E0
 2 144
47 GO:0060318 definitive erythrocyte differentiation 5.251E-3 3.490E-2
2.214E-1
1.000E0
 1 7
48 GO:0009756 carbohydrate mediated signaling 5.251E-3 3.490E-2
2.214E-1
1.000E0
 1 7
49 GO:0007286 spermatid development 5.433E-3 3.537E-2
2.244E-1
1.000E0
 2 149
50 GO:0048515 spermatid differentiation 5.939E-3 3.761E-2
2.386E-1
1.000E0
 2 156
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 14 input genes in category / 34 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016514 SWI/SNF complex 1.647E-34 5.601E-33 2.307E-32 5.601E-33 11 15
2 GO:0070603 SWI/SNF superfamily-type complex 2.083E-31 3.542E-30 1.459E-29 7.083E-30 13 74
3 GO:0071565 nBAF complex 5.753E-31 6.520E-30 2.685E-29 1.956E-29 10 14
4 GO:0071564 npBAF complex 4.818E-28 4.095E-27 1.686E-26 1.638E-26 9 12
5 GO:0000790 nuclear chromatin 1.757E-11 1.195E-10 4.921E-10 5.975E-10 8 324
6 GO:0000785 chromatin 4.501E-10 2.551E-9 1.050E-8 1.530E-8 8 487
7 GO:0017053 transcriptional repressor complex 1.494E-3 7.258E-3 2.989E-2
5.081E-2
 2 79
8 GO:0005726 perichromatin fibrils 3.667E-3 1.559E-2
6.419E-2
1.247E-1
 1 5
9 GO:0031011 Ino80 complex 1.024E-2 3.255E-2
1.341E-1
3.481E-1
 1 14
10 GO:0033202 DNA helicase complex 1.096E-2 3.255E-2
1.341E-1
3.728E-1
 1 15
11 GO:0001741 XY body 1.242E-2 3.255E-2
1.341E-1
4.222E-1
 1 17
12 GO:0043189 H4/H2A histone acetyltransferase complex 1.387E-2 3.255E-2
1.341E-1
4.716E-1
 1 19
13 GO:1902562 H4 histone acetyltransferase complex 1.387E-2 3.255E-2
1.341E-1
4.716E-1
 1 19
14 GO:0035267 NuA4 histone acetyltransferase complex 1.387E-2 3.255E-2
1.341E-1
4.716E-1
 1 19
15 GO:0097346 INO80-type complex 1.532E-2 3.255E-2
1.341E-1
5.209E-1
 1 21
16 GO:0000780 condensed nuclear chromosome, centromeric region 1.532E-2 3.255E-2
1.341E-1
5.209E-1
 1 21
17 GO:0005719 nuclear euchromatin 2.182E-2 4.364E-2
1.797E-1
7.418E-1
 1 30
18 GO:0000803 sex chromosome 2.326E-2 4.393E-2
1.809E-1
7.907E-1
 1 32
Show 13 more annotations

4: Human Phenotype [Display Chart] 7 input genes in category / 472 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0008398 Hypoplastic fifth fingernail 5.988E-11 4.710E-9 3.173E-8 2.826E-8 4 7
2 HP:0010343 Aplasia/Hypoplasia of the 5th toe 5.988E-11 4.710E-9 3.173E-8 2.826E-8 4 7
3 HP:0010392 Abnormality of the distal phalanx of the 5th toe 5.988E-11 4.710E-9 3.173E-8 2.826E-8 4 7
4 HP:0100371 Aplasia/Hypoplasia of the distal phalanx of the 5th toe 5.988E-11 4.710E-9 3.173E-8 2.826E-8 4 7
5 HP:0010383 Aplasia/Hypoplasia of the phalanges of the 5th toe 5.988E-11 4.710E-9 3.173E-8 2.826E-8 4 7
6 HP:0010342 Abnormality of the phalanges of the 5th toe 5.988E-11 4.710E-9 3.173E-8 2.826E-8 4 7
7 HP:0011937 Hypoplastic fifth toenail 1.197E-10 8.071E-9 5.436E-8 5.649E-8 4 8
8 HP:0009239 Aplasia/Hypoplasia of the distal phalanx of the 5th finger 8.447E-10 4.984E-8 3.357E-7 3.987E-7 4 12
9 HP:0004225 Abnormality of the distal phalanx of the 5th finger 1.706E-9 8.949E-8 6.027E-7 8.054E-7 4 14
10 HP:0010185 Aplasia/Hypoplasia of the distal phalanges of the toes 3.099E-9 1.463E-7 9.853E-7 1.463E-6 4 16
11 HP:0009928 Thick nasal alae 6.590E-9 2.592E-7 1.746E-6 3.111E-6 4 19
12 HP:0010182 Abnormality of the distal phalanges of the toes 6.590E-9 2.592E-7 1.746E-6 3.111E-6 4 19
13 HP:0000527 Long eyelashes 8.160E-9 2.963E-7 1.995E-6 3.851E-6 5 64
14 HP:0001338 Partial agenesis of the corpus callosum 2.533E-8 8.539E-7 5.751E-6 1.196E-5 4 26
15 HP:0005108 Abnormality of the intervertebral disk 4.018E-8 1.264E-6 8.515E-6 1.896E-5 4 29
16 HP:0010173 Aplasia/Hypoplasia of the phalanges of the toes 4.634E-8 1.286E-6 8.665E-6 2.187E-5 4 30
17 HP:0009376 Aplasia/Hypoplasia of the phalanges of the 5th finger 4.634E-8 1.286E-6 8.665E-6 2.187E-5 4 30
18 HP:0004213 Abnormal 5th finger phalanx morphology 6.074E-8 1.593E-6 1.073E-5 2.867E-5 4 32
19 HP:0006498 Aplasia/Hypoplasia of the patella 6.908E-8 1.630E-6 1.098E-5 3.261E-5 4 33
20 HP:0002217 Slow-growing hair 6.908E-8 1.630E-6 1.098E-5 3.261E-5 4 33
21 HP:0000179 Thick lower lip vermilion 8.365E-8 1.812E-6 1.220E-5 3.948E-5 5 101
22 HP:0001804 Hypoplastic fingernail 8.830E-8 1.812E-6 1.220E-5 4.168E-5 4 35
23 HP:0011363 Abnormality of hair growth rate 8.830E-8 1.812E-6 1.220E-5 4.168E-5 4 35
24 HP:0040170 Abnormality of hair growth 9.929E-8 1.953E-6 1.315E-5 4.686E-5 4 36
25 HP:0000184 Prominent lips 1.230E-7 2.233E-6 1.504E-5 5.807E-5 5 109
26 HP:0010161 Abnormality of the phalanges of the toes 1.230E-7 2.233E-6 1.504E-5 5.807E-5 5 109
27 HP:0001800 Hypoplastic toenails 2.073E-7 3.418E-6 2.302E-5 9.783E-5 4 43
28 HP:0002556 Thin scalp hair 2.173E-7 3.418E-6 2.302E-5 1.025E-4 5 122
29 HP:0002209 Sparse scalp hair 2.173E-7 3.418E-6 2.302E-5 1.025E-4 5 122
30 HP:0002237 Thin hair 2.173E-7 3.418E-6 2.302E-5 1.025E-4 5 122
31 HP:0009832 Abnormal distal phalanx morphology of finger 2.264E-7 3.447E-6 2.322E-5 1.069E-4 5 123
32 HP:0008384 Aplastic/hypoplastic fingernail 3.260E-7 4.808E-6 3.238E-5 1.539E-4 4 48
33 HP:0000154 Wide mouth 4.830E-7 6.598E-6 4.444E-5 2.280E-4 5 143
34 HP:0000181 Macrostomia 4.830E-7 6.598E-6 4.444E-5 2.280E-4 5 143
35 HP:0000294 Low anterior hairline 4.893E-7 6.598E-6 4.444E-5 2.309E-4 4 53
36 HP:0010760 Absent toe 5.282E-7 6.738E-6 4.538E-5 2.493E-4 4 54
37 HP:0011306 Aplasia of the toes 5.282E-7 6.738E-6 4.538E-5 2.493E-4 4 54
38 HP:0010322 Abnormality of the 5th toe 6.128E-7 7.611E-6 5.126E-5 2.892E-4 4 56
39 HP:0012471 Thick vermilion border 9.892E-7 1.197E-5 8.064E-5 4.669E-4 5 165
40 HP:0000965 Cutis marmorata 1.196E-6 1.412E-5 9.507E-5 5.646E-4 4 66
41 HP:0007598 Bilateral single transverse palmar creases 1.272E-6 1.464E-5 9.859E-5 6.002E-4 4 67
42 HP:0003042 Elbow dislocation 1.519E-6 1.687E-5 1.136E-4 7.168E-4 4 70
43 HP:0030310 Upper extremity joint dislocation 1.609E-6 1.687E-5 1.136E-4 7.592E-4 4 71
44 HP:0002673 Coxa valga 1.609E-6 1.687E-5 1.136E-4 7.592E-4 4 71
45 HP:0003045 Abnormality of the patella 1.609E-6 1.687E-5 1.136E-4 7.592E-4 4 71
46 HP:0000086 Ectopic kidney 1.800E-6 1.847E-5 1.244E-4 8.496E-4 4 73
47 HP:0000178 Abnormality of lower lip 2.001E-6 2.009E-5 1.353E-4 9.444E-4 5 190
48 HP:0003298 Spina bifida occulta 2.118E-6 2.083E-5 1.403E-4 9.999E-4 4 76
49 HP:0000499 Abnormal eyelash morphology 2.220E-6 2.138E-5 1.440E-4 1.048E-3 5 194
50 HP:0000599 Abnormality of the frontal hairline 2.477E-6 2.338E-5 1.575E-4 1.169E-3 4 79
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 14 input genes in category / 471 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0001237 enlarged spinous cells 1.017E-5 4.790E-3 3.225E-2 4.790E-3 2 4
2 MP:0013958 decreased small intestine length 2.538E-5 5.978E-3 4.025E-2 1.196E-2 2 6
3 MP:0009476 enlarged cecum 1.313E-4 1.802E-2
1.213E-1
6.184E-2
 2 13
4 MP:0008802 abnormal intestinal smooth muscle morphology 1.530E-4 1.802E-2
1.213E-1
7.209E-2
 2 14
5 MP:0013956 decreased colon length 5.416E-4 3.974E-2
2.676E-1
2.551E-1
 2 26
6 MP:0013960 decreased large intestine length 5.416E-4 3.974E-2
2.676E-1
2.551E-1
 2 26
7 MP:0002731 megacolon 6.289E-4 3.974E-2
2.676E-1
2.962E-1
 2 28
8 MP:0010564 abnormal fetal ductus arteriosus morphology 6.750E-4 3.974E-2
2.676E-1
3.179E-1
 2 29
9 MP:0013916 decreased intestine length 9.290E-4 4.444E-2
2.992E-1
4.376E-1
 2 34
10 MP:0020594 decreased cerebral cortex cell number 1.352E-3 4.444E-2
2.992E-1
6.368E-1
 1 1
11 MP:0011684 coronary-cameral fistula to right ventricle 1.352E-3 4.444E-2
2.992E-1
6.368E-1
 1 1
12 MP:0020592 abnormal cerebral cortex cell number 1.352E-3 4.444E-2
2.992E-1
6.368E-1
 1 1
13 MP:0009430 increased embryo weight 1.352E-3 4.444E-2
2.992E-1
6.368E-1
 1 1
14 MP:0011657 coronary-cameral fistula 1.352E-3 4.444E-2
2.992E-1
6.368E-1
 1 1
15 MP:0000494 abnormal cecum morphology 1.555E-3 4.444E-2
2.992E-1
7.322E-1
 2 44
16 MP:0003667 increased hemangiosarcoma incidence 1.555E-3 4.444E-2
2.992E-1
7.322E-1
 2 44
17 MP:0014138 abnormal germ layer morphology 1.633E-3 4.444E-2
2.992E-1
7.690E-1
 3 180
18 MP:0000740 impaired smooth muscle contractility 1.698E-3 4.444E-2
2.992E-1
7.999E-1
 2 46
Show 13 more annotations

6: Domain [Display Chart] 14 input genes in category / 101 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR032450 SMARCC N InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
2 IPR014978 Gln-Leu-Gln QLQ InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
3 PF16496 SWIRM-assoc 2 Pfam 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
4 IPR032448 SWIRM-assoc InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
5 SM00951 QLQ SMART 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
6 IPR032451 SMARCC C InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
7 PF16495 SWIRM-assoc 1 Pfam 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
8 IPR021906 BAF250/Osa InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
9 PF12031 BAF250 C Pfam 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
10 PF16498 SWIRM-assoc 3 Pfam 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
11 SM01314 SnAC SMART 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
12 PF08880 QLQ Pfam 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
13 PS51666 QLQ PROSITE 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
14 PF14619 SnAC Pfam 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
15 IPR033388 BAF250 C InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
16 IPR029295 SnAC InterPro 5.185E-7 3.273E-6 1.701E-5 5.237E-5 2 2
17 IPR007726 SS18 fam InterPro 1.555E-6 7.468E-6 3.881E-5 1.571E-4 2 3
18 SM00151 SWIB SMART 1.555E-6 7.468E-6 3.881E-5 1.571E-4 2 3
19 IPR019835 SWIB domain InterPro 1.555E-6 7.468E-6 3.881E-5 1.571E-4 2 3
20 PF05030 SSXT Pfam 1.555E-6 7.468E-6 3.881E-5 1.571E-4 2 3
21 PF00176 SNF2 N Pfam 1.627E-6 7.468E-6 3.881E-5 1.643E-4 3 32
22 IPR000330 SNF2 N InterPro 1.627E-6 7.468E-6 3.881E-5 1.643E-4 3 32
23 PF07529 HSA Pfam 3.109E-6 1.208E-5 6.276E-5 3.140E-4 2 4
24 IPR014012 HSA dom InterPro 3.109E-6 1.208E-5 6.276E-5 3.140E-4 2 4
25 PS51204 HSA PROSITE 3.109E-6 1.208E-5 6.276E-5 3.140E-4 2 4
26 SM00573 HSA SMART 3.109E-6 1.208E-5 6.276E-5 3.140E-4 2 4
27 PF02201 SWIB Pfam 5.179E-6 1.937E-5 1.007E-4 5.231E-4 2 5
28 IPR006576 BRK domain InterPro 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
29 IPR003121 SWIB MDM2 domain InterPro 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
30 IPR007526 SWIRM InterPro 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
31 PF07533 BRK Pfam 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
32 SM00592 BRK SMART 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
33 PS50934 SWIRM PROSITE 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
34 PF04433 SWIRM Pfam 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
35 1.10.245.10 - Gene3D 7.765E-6 2.241E-5 1.165E-4 7.843E-4 2 6
36 PF01388 ARID Pfam 5.415E-5 1.367E-4 7.106E-4 5.469E-3 2 15
37 PS51011 ARID PROSITE 5.415E-5 1.367E-4 7.106E-4 5.469E-3 2 15
38 1.10.150.60 - Gene3D 5.415E-5 1.367E-4 7.106E-4 5.469E-3 2 15
39 IPR001606 ARID dom InterPro 5.415E-5 1.367E-4 7.106E-4 5.469E-3 2 15
40 SM00501 BRIGHT SMART 5.415E-5 1.367E-4 7.106E-4 5.469E-3 2 15
41 IPR004001 Actin CS InterPro 6.185E-5 1.430E-4 7.433E-4 6.247E-3 2 16
42 SM00490 HELICc SMART 6.298E-5 1.430E-4 7.433E-4 6.361E-3 3 107
43 PF00271 Helicase C Pfam 6.298E-5 1.430E-4 7.433E-4 6.361E-3 3 107
44 IPR001650 Helicase C InterPro 6.475E-5 1.430E-4 7.433E-4 6.539E-3 3 108
45 PS51194 HELICASE CTER PROSITE 6.655E-5 1.430E-4 7.433E-4 6.722E-3 3 109
46 PS51192 HELICASE ATP BIND 1 PROSITE 6.655E-5 1.430E-4 7.433E-4 6.722E-3 3 109
47 SM00487 DEXDc SMART 6.655E-5 1.430E-4 7.433E-4 6.722E-3 3 109
48 IPR014001 Helicase ATP-bd InterPro 6.839E-5 1.439E-4 7.479E-4 6.907E-3 3 110
49 PS00432 ACTINS 2 PROSITE 7.007E-5 1.444E-4 7.507E-4 7.077E-3 2 17
50 IPR018359 Bromodomain CS InterPro 1.668E-4 3.303E-4 1.717E-3 1.685E-2 2 26
Show 45 more annotations

7: Pathway [Display Chart] 13 input genes in category / 26 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1270439 RMTs methylate histone arginines BioSystems: REACTOME 2.512E-23 6.530E-22 2.517E-21 6.530E-22 11 79
2 1270433 Chromatin organization BioSystems: REACTOME 4.413E-17 3.825E-16 1.474E-15 1.147E-15 11 279
3 1270434 Chromatin modifying enzymes BioSystems: REACTOME 4.413E-17 3.825E-16 1.474E-15 1.147E-15 11 279
4 P00057 Wnt signaling pathway PantherDB 1.855E-12 1.206E-11 4.648E-11 4.824E-11 9 305
5 138014 Glucocorticoid receptor regulatory network BioSystems: Pathway Interaction Database 1.195E-6 6.212E-6 2.394E-5 3.106E-5 4 82
6 138027 Regulation of Androgen receptor activity BioSystems: Pathway Interaction Database 1.695E-5 7.343E-5 2.830E-4 4.406E-4 3 50
Show 1 more annotation

8: Pubmed [Display Chart] 14 input genes in category / 1308 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 8804307 Diversity and specialization of mammalian SWI/SNF complexes. Pubmed 3.634E-35 2.376E-32 1.843E-31 4.753E-32 10 12
2 11734557 SYT associates with human SNF/SWI complexes and the C-terminal region of its fusion partner SSX1 targets histones. Pubmed 3.634E-35 2.376E-32 1.843E-31 4.753E-32 10 12
3 23785148 Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. Pubmed 1.653E-33 7.206E-31 5.588E-30 2.162E-30 10 15
4 24335282 Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation. Pubmed 1.648E-32 5.388E-30 4.178E-29 2.155E-29 11 34
5 11078522 The human SWI/SNF-B chromatin-remodeling complex is related to yeast rsc and localizes at kinetochores of mitotic chromosomes. Pubmed 9.248E-31 2.419E-28 1.876E-27 1.210E-27 9 12
6 19279220 An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Pubmed 1.797E-30 3.918E-28 3.038E-27 2.351E-27 10 25
7 8895581 Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. Pubmed 3.005E-30 4.914E-28 3.810E-27 3.931E-27 9 13
8 11726552 Fanconi anemia protein, FANCA, associates with BRG1, a component of the human SWI/SNF complex. Pubmed 3.005E-30 4.914E-28 3.810E-27 3.931E-27 9 13
9 12368262 Identification of a polymorphic, neuron-specific chromatin remodeling complex. Pubmed 2.103E-29 2.751E-27 2.133E-26 2.751E-26 9 15
10 17640523 An essential switch in subunit composition of a chromatin remodeling complex during neural development. Pubmed 2.103E-29 2.751E-27 2.133E-26 2.751E-26 9 15
11 20305087 A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency. Pubmed 2.403E-29 2.857E-27 2.216E-26 3.143E-26 11 61
12 14559996 mSin3A/histone deacetylase 2- and PRMT5-containing Brg1 complex is involved in transcriptional repression of the Myc target gene cad. Pubmed 2.042E-28 2.226E-26 1.726E-25 2.671E-25 9 18
13 10078207 Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits. Pubmed 1.204E-27 1.211E-25 9.393E-25 1.575E-24 8 10
14 20460684 Requiem protein links RelB/p52 and the Brm-type SWI/SNF complex in a noncanonical NF-kappaB pathway. Pubmed 5.436E-24 5.079E-22 3.938E-21 7.110E-21 8 21
15 12665591 Novel SWI/SNF chromatin-remodeling complexes contain a mixed-lineage leukemia chromosomal translocation partner. Pubmed 1.751E-23 1.431E-21 1.110E-20 2.290E-20 7 10
16 15985610 PBAF chromatin-remodeling complex requires a novel specificity subunit, BAF200, to regulate expression of selective interferon-responsive genes. Pubmed 1.751E-23 1.431E-21 1.110E-20 2.290E-20 7 10
17 18809673 BRD7, a novel PBAF-specific SWI/SNF subunit, is required for target gene activation and repression in embryonic stem cells. Pubmed 2.503E-22 1.926E-20 1.493E-19 3.274E-19 7 13
18 16230384 The p270 (ARID1A/SMARCF1) subunit of mammalian SWI/SNF-related complexes is essential for normal cell cycle arrest. Pubmed 6.969E-22 4.797E-20 3.720E-19 9.115E-19 6 6
19 16940996 Testing for association between MeCP2 and the brahma-associated SWI/SNF chromatin-remodeling complex. Pubmed 6.969E-22 4.797E-20 3.720E-19 9.115E-19 6 6
20 26986003 Epigenetic regulation by BAF (mSWI/SNF) chromatin remodeling complexes is indispensable for embryonic development. Pubmed 1.951E-20 1.276E-18 9.891E-18 2.551E-17 6 8
21 9845365 Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Pubmed 5.851E-20 3.644E-18 2.826E-17 7.653E-17 6 9
22 14729568 A methylation-mediator complex in hormone signaling. Pubmed 1.462E-19 8.695E-18 6.742E-17 1.913E-16 6 10
23 11018012 Functional selectivity of recombinant mammalian SWI/SNF subunits. Pubmed 3.217E-19 1.829E-17 1.418E-16 4.207E-16 6 11
24 28611094 Agonist-specific protein interactomes of glucocorticoid and androgen receptor as revealed by proximity mapping. Pubmed 6.214E-19 3.387E-17 2.626E-16 8.128E-16 8 78
25 27637333 Identification of Novel Nuclear Factor of Activated T Cell (NFAT)-associated Proteins in T Cells. Pubmed 1.659E-18 8.680E-17 6.731E-16 2.170E-15 9 178
26 11784859 Role of the Sin3-histone deacetylase complex in growth regulation by the candidate tumor suppressor p33(ING1). Pubmed 5.571E-18 2.802E-16 2.173E-15 7.286E-15 6 16
27 27716508 Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor. Pubmed 1.448E-17 7.016E-16 5.440E-15 1.894E-14 7 50
28 25081545 Numerous BAF complex genes are mutated in Coffin-Siris syndrome. Pubmed 1.774E-17 8.286E-16 6.425E-15 2.320E-14 5 6
29 16217013 Heterogeneous nuclear ribonucleoprotein C1/C2, MeCP1, and SWI/SNF form a chromatin remodeling complex at the beta-globin locus control region. Pubmed 1.886E-17 8.508E-16 6.597E-15 2.467E-14 6 19
30 21532573 Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes. Pubmed 2.234E-17 9.739E-16 7.552E-15 2.922E-14 7 53
31 23540691 Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Pubmed 6.207E-17 2.460E-15 1.908E-14 8.119E-14 5 7
32 28369036 Chromatin-remodeling factor SMARCD2 regulates transcriptional networks controlling differentiation of neutrophil granulocytes. Pubmed 6.207E-17 2.460E-15 1.908E-14 8.119E-14 5 7
33 21118156 Target genes of the largest human SWI/SNF complex subunit control cell growth. Pubmed 6.207E-17 2.460E-15 1.908E-14 8.119E-14 5 7
34 23643363 Chromatin regulation by BAF170 controls cerebral cortical size and thickness. Pubmed 1.599E-16 6.150E-15 4.769E-14 2.091E-13 6 26
35 20362541 An Oct4-centered protein interaction network in embryonic stem cells. Pubmed 2.458E-16 9.186E-15 7.123E-14 3.215E-13 8 161
36 20086098 Mammalian SWI/SNF--a subunit BAF250/ARID1 is an E3 ubiquitin ligase that targets histone H2B. Pubmed 3.723E-16 1.353E-14 1.049E-13 4.869E-13 5 9
37 23129809 ARID1a-DNA interactions are required for promoter occupancy by SWI/SNF. Pubmed 7.444E-16 2.562E-14 1.987E-13 9.737E-13 5 10
38 29374058 Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes. Pubmed 7.444E-16 2.562E-14 1.987E-13 9.737E-13 5 10
39 12917342 BAF60a mediates critical interactions between nuclear receptors and the BRG1 chromatin-remodeling complex for transactivation. Pubmed 1.364E-15 4.576E-14 3.548E-13 1.785E-12 5 11
40 16287714 A Brg1 mutation that uncouples ATPase activity from chromatin remodeling reveals an essential role for SWI/SNF-related complexes in beta-globin expression and erythroid development. Pubmed 5.909E-15 1.932E-13 1.498E-12 7.729E-12 5 14
41 17255939 Distinct mammalian SWI/SNF chromatin remodeling complexes with opposing roles in cell-cycle control. Pubmed 8.862E-15 2.827E-13 2.192E-12 1.159E-11 5 15
42 15170388 Two related ARID family proteins are alternative subunits of human SWI/SNF complexes. Pubmed 1.129E-14 3.357E-13 2.603E-12 1.477E-11 4 4
43 11988099 Cloning and characterization of hELD/OSA1, a novel BRG1 interacting protein. Pubmed 1.129E-14 3.357E-13 2.603E-12 1.477E-11 4 4
44 24421395 Residual complexes containing SMARCA2 (BRM) underlie the oncogenic drive of SMARCA4 (BRG1) mutation. Pubmed 1.129E-14 3.357E-13 2.603E-12 1.477E-11 4 4
45 9710619 A human RNA polymerase II complex containing factors that modify chromatin structure. Pubmed 1.289E-14 3.746E-13 2.905E-12 1.686E-11 5 16
46 28068325 TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation. Pubmed 2.527E-14 7.186E-13 5.572E-12 3.305E-11 5 18
47 23556151 Coffin-Siris Syndrome Pubmed 5.645E-14 1.393E-12 1.080E-11 7.384E-11 4 5
48 12200431 Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors. Pubmed 5.645E-14 1.393E-12 1.080E-11 7.384E-11 4 5
49 16199878 Regulating SWI/SNF subunit levels via protein-protein interactions and proteasomal degradation: BAF155 and BAF170 limit expression of BAF57. Pubmed 5.645E-14 1.393E-12 1.080E-11 7.384E-11 4 5
50 18086889 The HSA domain of BRG1 mediates critical interactions required for glucocorticoid receptor-dependent transcriptional activation in vivo. Pubmed 5.645E-14 1.393E-12 1.080E-11 7.384E-11 4 5
Show 45 more annotations

9: Interaction [Display Chart] 14 input genes in category / 651 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:DPF3 DPF3 interactions 4.383E-33 2.854E-30 2.014E-29 2.854E-30 13 53
2 int:DPF2 DPF2 interactions 3.419E-32 1.113E-29 7.854E-29 2.226E-29 13 61
3 int:SS18 SS18 interactions 1.790E-30 3.885E-28 2.742E-27 1.166E-27 12 46
4 int:BCL7A BCL7A interactions 2.017E-29 3.282E-27 2.316E-26 1.313E-26 12 55
5 int:BCL7C BCL7C interactions 2.260E-28 2.943E-26 2.077E-25 1.472E-25 12 66
6 int:SMARCD1 SMARCD1 interactions 9.870E-28 1.071E-25 7.557E-25 6.426E-25 13 127
7 int:SMARCA2 SMARCA2 interactions 1.357E-27 1.262E-25 8.907E-25 8.836E-25 13 130
8 int:ARID1B ARID1B interactions 3.236E-26 2.634E-24 1.858E-23 2.107E-23 11 55
9 int:SMARCC2 SMARCC2 interactions 3.732E-26 2.700E-24 1.905E-23 2.430E-23 13 166
10 int:SMARCD2 SMARCD2 interactions 4.989E-26 3.248E-24 2.292E-23 3.248E-23 11 57
11 int:SMARCE1 SMARCE1 interactions 3.321E-24 1.965E-22 1.387E-21 2.162E-21 12 140
12 int:ARID1A ARID1A interactions 7.537E-24 4.089E-22 2.885E-21 4.906E-21 11 87
13 int:SMARCC1 SMARCC1 interactions 8.524E-24 4.269E-22 3.012E-21 5.549E-21 12 151
14 int:SMARCD3 SMARCD3 interactions 2.328E-23 1.083E-21 7.639E-21 1.516E-20 10 53
15 int:SMARCA4 SMARCA4 interactions 2.757E-23 1.196E-21 8.442E-21 1.795E-20 13 272
16 int:BCL7B BCL7B interactions 8.546E-23 3.477E-21 2.454E-20 5.563E-20 9 31
17 int:ACTL6A ACTL6A interactions 1.195E-21 4.578E-20 3.230E-19 7.782E-19 11 135
18 int:SMARCB1 SMARCB1 interactions 6.865E-20 2.483E-18 1.752E-17 4.469E-17 11 193
19 int:DPF1 DPF1 interactions 2.039E-19 6.988E-18 4.931E-17 1.328E-16 7 15
20 int:PHF10 PHF10 interactions 2.935E-19 9.553E-18 6.741E-17 1.911E-16 8 35
21 int:RELB RELB interactions 4.789E-17 1.417E-15 9.999E-15 3.117E-14 8 63
22 int:PBRM1 PBRM1 interactions 4.789E-17 1.417E-15 9.999E-15 3.117E-14 8 63
23 int:ARID2 ARID2 interactions 1.694E-16 4.794E-15 3.383E-14 1.103E-13 7 34
24 int:NFATC1 NFATC1 interactions 3.626E-16 9.836E-15 6.941E-14 2.361E-13 9 151
25 int:KLF1 KLF1 interactions 1.299E-15 3.383E-14 2.387E-13 8.457E-13 6 18
26 int:TFCP2L1 TFCP2L1 interactions 1.364E-15 3.414E-14 2.409E-13 8.876E-13 8 94
27 int:SS18L1 SS18L1 interactions 1.423E-15 3.432E-14 2.422E-13 9.266E-13 7 45
28 int:NFATC2 NFATC2 interactions 2.986E-15 6.942E-14 4.899E-13 1.944E-12 9 190
29 int:ACTL6B ACTL6B interactions 5.126E-14 1.151E-12 8.120E-12 3.337E-11 6 31
30 int:BRD9 BRD9 interactions 6.011E-13 1.304E-11 9.204E-11 3.913E-10 5 16
31 int:ING1 ING1 interactions 1.406E-12 2.953E-11 2.083E-10 9.153E-10 6 52
32 int:BRD7 BRD7 interactions 3.447E-12 7.012E-11 4.948E-10 2.244E-9 6 60
33 int:PDCD6 PDCD6 interactions 3.586E-12 7.075E-11 4.992E-10 2.335E-9 7 132
34 int:NR3C1 NR3C1 interactions 6.901E-12 1.321E-10 9.324E-10 4.492E-9 8 268
35 int:TOP2B TOP2B interactions 2.216E-11 4.122E-10 2.909E-9 1.443E-8 6 81
36 int:AR AR interactions 3.563E-11 6.444E-10 4.547E-9 2.320E-8 8 329
37 int:CHD7 CHD7 interactions 4.431E-11 7.797E-10 5.502E-9 2.885E-8 5 35
38 int:YAP1 YAP1 interactions 7.308E-11 1.252E-9 8.835E-9 4.758E-8 8 360
39 int:GATA1 GATA1 interactions 7.598E-11 1.268E-9 8.950E-9 4.946E-8 6 99
40 int:HDAC2 HDAC2 interactions 1.078E-10 1.754E-9 1.238E-8 7.017E-8 8 378
41 int:BICRA BICRA interactions 2.438E-10 3.871E-9 2.732E-8 1.587E-7 4 14
42 int:CARM1 CARM1 interactions 4.185E-10 6.487E-9 4.578E-8 2.725E-7 6 131
43 int:SALL4 SALL4 interactions 5.168E-10 7.824E-9 5.521E-8 3.364E-7 5 56
44 int:SMARCAD1 SMARCAD1 interactions 7.425E-10 1.099E-8 7.752E-8 4.834E-7 6 144
45 int:TBL1XR1 TBL1XR1 interactions 2.017E-9 2.919E-8 2.059E-7 1.313E-6 5 73
46 int:NCOR1 NCOR1 interactions 3.949E-9 5.588E-8 3.943E-7 2.571E-6 6 190
47 int:CDX2 CDX2 interactions 4.956E-9 6.864E-8 4.844E-7 3.226E-6 4 28
48 int:HIST1H3E HIST1H3E interactions 5.874E-9 7.967E-8 5.622E-7 3.824E-6 6 203
49 int:SIN3A SIN3A interactions 1.306E-8 1.736E-7 1.225E-6 8.504E-6 6 232
50 int:RUNX1 RUNX1 interactions 2.305E-8 3.002E-7 2.118E-6 1.501E-5 5 118
Show 45 more annotations

10: Cytoband [Display Chart] 14 input genes in category / 14 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 3q25.1-q26.1 3q25.1-q26.1 4.039E-4 5.655E-3 1.839E-2 5.655E-3 1 1
2 17q23-q24 17q23-q24 1.211E-3 8.479E-3 2.757E-2 1.696E-2 1 3
3 12q13-q14 12q13-q14 2.421E-3 1.130E-2 3.674E-2 3.390E-2 1 6
4 9p22.3 9p22.3 6.043E-3 2.115E-2
6.877E-2
8.460E-2
 1 15
5 20q13.3 20q13.3 8.050E-3 2.159E-2
7.019E-2
1.127E-1
 1 20
6 3q26.33 3q26.33 9.252E-3 2.159E-2
7.019E-2
1.295E-1
 1 23
7 1p35.3 1p35.3 1.365E-2 2.433E-2
7.911E-2
1.911E-1
 1 34
8 6q25.1 6q25.1 1.564E-2 2.433E-2
7.911E-2
2.190E-1
 1 39
9 7q22 7q22 1.564E-2 2.433E-2
7.911E-2
2.190E-1
 1 39
10 18q11.2 18q11.2 1.922E-2 2.690E-2
8.748E-2
2.690E-1
 1 48
11 12q13.2 12q13.2 2.199E-2 2.799E-2
9.101E-2
3.079E-1
 1 55
12 17q21.2 17q21.2 2.988E-2 3.486E-2
1.133E-1
4.183E-1
 1 75
13 3p21.31 3p21.31 4.082E-2 4.396E-2
1.429E-1
5.714E-1
 1 103
Show 8 more annotations

11: Transcription Factor Binding Site [Display Chart] 10 input genes in category / 136 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 6 input genes in category / 5 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 418 AT-rich interaction domain containing genenames.org 9.498E-6 4.749E-5 1.084E-4 4.749E-5 2 15
2 532 GATA zinc finger domain containing|Myb/SANT domain containing genenames.org 1.240E-4 3.099E-4 7.076E-4 6.198E-4 2 53
3 1329 YEATS domain containing|SRCAP complex genenames.org 2.965E-3 4.941E-3 1.128E-2 1.482E-2 1 9
4 595 INO80 complex genenames.org 4.937E-3 6.171E-3 1.409E-2 2.469E-2 1 15

13: Coexpression [Display Chart] 14 input genes in category / 1180 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5160 Genes up-regulated in comparison of macrophages versus macrophages exposed to L. major. MSigDB C7: Immunologic Signatures (v6.0) 5.068E-6 5.980E-3 4.575E-2 5.980E-3 4 200
2 18722011-SuppTable2j Human Leukemia Sanchez-Guijo08 77genes GeneSigDB 1.115E-5 6.576E-3
5.031E-2
 1.315E-2 3 74
3 M16858 Genes down-regulated in blood samples from bladder cancer patients. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.057E-5 3.169E-2
2.425E-1
9.508E-2
 4 405
4 M8190 Genes up-regulated in double positive thymocytes: HDAC7 [GeneID=51564] knockout versus over-expressing HDAC7 [GeneID=51564] fused with VP16. MSigDB C7: Immunologic Signatures (v6.0) 1.914E-4 3.639E-2
2.784E-1
2.259E-1
 3 192
5 18316601-Table1 Human Breast Rizki08 204genes GeneSigDB 2.096E-4 3.639E-2
2.784E-1
2.473E-1
 3 198
6 M3048 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.159E-4 3.639E-2
2.784E-1
2.548E-1
 3 200
7 M5637 Genes up-regulated in comparison of anergy induced CD4 [GeneID=920] T cells versus conventional CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 2.159E-4 3.639E-2
2.784E-1
2.548E-1
 3 200
8 15572690-SuppTable5b Mouse Leukemia Walter04 62genes b GeneSigDB 2.887E-4 4.156E-2
3.180E-1
3.407E-1
 2 42
9 M1554 Genes up-regulated in H1299 cells (lung cancer) by expression of SMARCA4 [GeneID=6597] off a plasmid vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.170E-4 4.156E-2
3.180E-1
3.741E-1
 2 44
10 15572690-SuppTable5a Mouse Leukemia Walter04 62genes a GeneSigDB 3.775E-4 4.454E-2
3.408E-1
4.454E-1
 2 48
11 14673169-TableA1-1 Human Breast Hendricks04 71genes BRG1 up GeneSigDB 4.603E-4 4.938E-2
3.778E-1
5.432E-1
 2 53
Show 6 more annotations

14: Coexpression Atlas [Display Chart] 14 input genes in category / 429 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Loop of Henle (LH)/Loop of Henle (LH) b Loop of Henle (LH)/Loop of Henle (LH) b 6.372E-5 1.589E-2
1.055E-1
 2.733E-2 3 125
2 10X Human 68K PBMC CD4+ T Helper2 Subtype CD4+ T Helper2-CD4+ T Helper2 c2 Top 200 Genes 10X Human 68K PBMC CD4+ T Helper2 Subtype CD4+ T Helper2-CD4+ T Helper2 c2 Top 200 Genes 7.409E-5 1.589E-2
1.055E-1
 3.178E-2 4 374

15: Computational [Display Chart] 13 input genes in category / 107 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M5047 MORF DDB1 Neighborhood of DDB1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.954E-4 2.091E-2
1.099E-1
 2.091E-2 4 241
2 M2127 GCM FANCC Neighborhood of FANCC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.808E-4 2.573E-2
1.352E-1
5.145E-2
 3 124
3 M6968 GCM SMARCC1 Neighborhood of SMARCC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.005E-3 2.576E-2
1.354E-1
1.076E-1
 2 37
4 M18347 GCM AIP Neighborhood of AIP MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.175E-3 2.576E-2
1.354E-1
1.257E-1
 2 40
5 M4092 MODULE 197 Genes in the cancer module 197. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.289E-3 2.576E-2
1.354E-1
1.379E-1
 3 174
6 M16249 GCM VAV1 Neighborhood of VAV1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.620E-3 2.576E-2
1.354E-1
1.733E-1
 2 47
7 M7462 MORF RPA2 Neighborhood of RPA2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.685E-3 2.576E-2
1.354E-1
1.803E-1
 3 191
8 M1964 MORF PRKAG1 Neighborhood of PRKAG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.493E-3 3.334E-2
1.752E-1
2.667E-1
 3 219
Show 3 more annotations

16: MicroRNA [Display Chart] 14 input genes in category / 706 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CACTGTG,MIR-128A:MSigDB CACTGTG,MIR-128A:MSigDB MSigDB 3.430E-7 1.211E-4 8.642E-4 2.422E-4 4 315
2 CACTGTG,MIR-128B:MSigDB CACTGTG,MIR-128B:MSigDB MSigDB 3.430E-7 1.211E-4 8.642E-4 2.422E-4 4 315
3 hsa-miR-567:PITA hsa-miR-567:PITA TOP PITA 4.257E-6 9.738E-4 6.951E-3 3.006E-3 3 166
4 hsa-miR-1228:PITA hsa-miR-1228:PITA TOP PITA 5.517E-6 9.738E-4 6.951E-3 3.895E-3 3 181
5 hsa-miR-3202:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.823E-5 2.442E-3 1.743E-2 1.287E-2 3 270
6 ATGTACA,MIR-493:MSigDB ATGTACA,MIR-493:MSigDB MSigDB 2.349E-5 2.442E-3 1.743E-2 1.659E-2 3 294
7 hsa-miR-324-5p:Functional MTI Functional MTI miRTarbase 2.421E-5 2.442E-3 1.743E-2 1.709E-2 3 297
8 hsa-miR-488:PITA hsa-miR-488:PITA TOP PITA 3.194E-5 2.511E-3 1.792E-2 2.255E-2 3 326
9 hsa-miR-212:PITA hsa-miR-212:PITA TOP PITA 3.557E-5 2.511E-3 1.792E-2 2.511E-2 3 338
10 hsa-miR-132:PITA hsa-miR-132:PITA TOP PITA 3.557E-5 2.511E-3 1.792E-2 2.511E-2 3 338
11 hsa-miR-410:PITA hsa-miR-410:PITA TOP PITA 4.432E-5 2.844E-3 2.030E-2 3.129E-2 3 364
12 hsa-miR-222-3p:Functional MTI Functional MTI miRTarbase 5.604E-5 3.297E-3 2.353E-2 3.957E-2 3 394
13 hsa-miR-539-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.655E-5 4.158E-3 2.967E-2
5.405E-2
 2 67
14 hsa-miR-485-3p:Functional MTI Functional MTI miRTarbase 9.093E-5 4.199E-3 2.997E-2
6.420E-2
 2 73
15 ACCAAAG,MIR-9:MSigDB ACCAAAG,MIR-9:MSigDB MSigDB 9.502E-5 4.199E-3 2.997E-2
6.709E-2
 3 471
16 hsa-miR-101:PITA hsa-miR-101:PITA TOP PITA 9.987E-5 4.199E-3 2.997E-2
7.051E-2
 3 479
17 hsa-miR-1825:mirSVR highEffct hsa-miR-1825:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.011E-4 4.199E-3 2.997E-2
7.138E-2
 3 481
18 hsa-miR-490-3p:mirSVR highEffct hsa-miR-490-3p:mirSVR conserved highEffect-0.5 MicroRNA.org 1.127E-4 4.419E-3 3.154E-2
7.955E-2
 3 499
19 hsa-miR-153-3p:Functional MTI Functional MTI miRTarbase 1.234E-4 4.584E-3 3.272E-2
8.709E-2
 2 85
20 hsa-miR-4518:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.509E-4 4.923E-3 3.514E-2
1.065E-1
 2 94
21 hsa-miR-324-5p:PITA hsa-miR-324-5p:PITA TOP PITA 1.541E-4 4.923E-3 3.514E-2
1.088E-1
 2 95
22 hsa-miR-1266-5p:Functional MTI Functional MTI miRTarbase 1.541E-4 4.923E-3 3.514E-2
1.088E-1
 2 95
23 hsa-miR-219-1-3p:PITA hsa-miR-219-1-3p:PITA TOP PITA 1.607E-4 4.923E-3 3.514E-2
1.134E-1
 2 97
24 hsa-miR-448:Functional MTI Functional MTI miRTarbase 1.674E-4 4.923E-3 3.514E-2
1.182E-1
 2 99
25 hsa-miR-491-5p:PITA hsa-miR-491-5p:PITA TOP PITA 1.955E-4 5.521E-3 3.940E-2
1.380E-1
 2 107
26 hsa-miR-526a:PITA hsa-miR-526a:PITA TOP PITA 2.582E-4 6.076E-3 4.337E-2
1.823E-1
 2 123
27 hsa-miR-519b-5p:PITA hsa-miR-519b-5p:PITA TOP PITA 2.582E-4 6.076E-3 4.337E-2
1.823E-1
 2 123
28 hsa-miR-518d-5p:PITA hsa-miR-518d-5p:PITA TOP PITA 2.582E-4 6.076E-3 4.337E-2
1.823E-1
 2 123
29 hsa-miR-520c-5p:PITA hsa-miR-520c-5p:PITA TOP PITA 2.582E-4 6.076E-3 4.337E-2
1.823E-1
 2 123
30 hsa-miR-519c-5p:PITA hsa-miR-519c-5p:PITA TOP PITA 2.582E-4 6.076E-3 4.337E-2
1.823E-1
 2 123
31 hsa-miR-486-5p:PITA hsa-miR-486-5p:PITA TOP PITA 2.839E-4 6.455E-3 4.607E-2
2.004E-1
 2 129
32 hsa-miR-625:PITA hsa-miR-625:PITA TOP PITA 2.927E-4 6.455E-3 4.607E-2
2.067E-1
 2 131
33 hsa-miR-1275:PITA hsa-miR-1275:PITA TOP PITA 3.017E-4 6.455E-3 4.607E-2
2.130E-1
 2 133
34 ACACTGG,MIR-199B:MSigDB ACACTGG,MIR-199B:MSigDB MSigDB 3.584E-4 7.229E-3
5.160E-2
2.530E-1
 2 145
35 ACACTGG,MIR-199A:MSigDB ACACTGG,MIR-199A:MSigDB MSigDB 3.584E-4 7.229E-3
5.160E-2
2.530E-1
 2 145
36 hsa-miR-544a:Functional MTI Functional MTI miRTarbase 3.885E-4 7.619E-3
5.438E-2
2.743E-1
 2 151
37 hsa-miR-4315:mirSVR highEffct hsa-miR-4315:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.040E-4 7.709E-3
5.502E-2
2.852E-1
 2 154
38 hsa-miR-532-3p:PITA hsa-miR-532-3p:PITA TOP PITA 4.198E-4 7.800E-3
5.567E-2
2.964E-1
 2 157
39 hsa-miR-619:PITA hsa-miR-619:PITA TOP PITA 4.803E-4 8.695E-3
6.206E-2
3.391E-1
 2 168
40 hsa-miR-647:PITA hsa-miR-647:PITA TOP PITA 5.209E-4 9.194E-3
6.562E-2
3.678E-1
 2 175
41 hsa-miR-1257:PITA hsa-miR-1257:PITA TOP PITA 5.570E-4 9.233E-3
6.590E-2
3.932E-1
 2 181
42 hsa-miR-1825:PITA hsa-miR-1825:PITA TOP PITA 5.631E-4 9.233E-3
6.590E-2
3.975E-1
 2 182
43 hsa-miR-765:PITA hsa-miR-765:PITA TOP PITA 5.692E-4 9.233E-3
6.590E-2
4.019E-1
 2 183
44 TGTGTGA,MIR-377:MSigDB TGTGTGA,MIR-377:MSigDB MSigDB 5.754E-4 9.233E-3
6.590E-2
4.063E-1
 2 184
45 hsa-miR-575:PITA hsa-miR-575:PITA TOP PITA 6.005E-4 9.412E-3
6.718E-2
4.240E-1
 2 188
46 AAAGACA,MIR-511:MSigDB AAAGACA,MIR-511:MSigDB MSigDB 6.133E-4 9.412E-3
6.718E-2
4.330E-1
 2 190
47 ATACTGT,MIR-144:MSigDB ATACTGT,MIR-144:MSigDB MSigDB 6.326E-4 9.503E-3
6.783E-2
4.466E-1
 2 193
48 hsa-miR-4476:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.722E-4 9.681E-3
6.910E-2
4.746E-1
 2 199
49 hsa-miR-6876-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.722E-4 9.681E-3
6.910E-2
4.746E-1
 2 199
50 hsa-miR-220c:PITA hsa-miR-220c:PITA TOP PITA 7.061E-4 9.681E-3
6.910E-2
4.985E-1
 2 204
Show 45 more annotations

17: Drug [Display Chart] 14 input genes in category / 3407 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000076473 8-bromoguanine Stitch 8.127E-16 2.769E-12 2.412E-11 2.769E-12 7 53
2 ctd:D011397 Promegestone CTD 2.863E-11 4.877E-8 4.249E-7 9.755E-8 5 41
3 CID009543496 2d41 Stitch 5.315E-7 6.036E-4 5.258E-3 1.811E-3 3 27
4 CID000007577 DAPM Stitch 1.149E-6 9.788E-4 8.527E-3 3.915E-3 4 136
5 CID000104795 5'-N-ethylcarboxamidoadenosine Stitch 3.068E-6 1.370E-3 1.193E-2 1.045E-2 4 174
6 CID000032281 TRH-T Stitch 3.119E-6 1.370E-3 1.193E-2 1.063E-2 3 48
7 1749 DN Ajmaline [4360-12-7]; Down 200; 12.2uM; HL60; HG-U133A Broad Institute CMAP Down 4.629E-6 1.370E-3 1.193E-2 1.577E-2 4 193
8 1547 DN Albendazole [54965-21-8]; Down 200; 15uM; HL60; HG-U133A Broad Institute CMAP Down 4.725E-6 1.370E-3 1.193E-2 1.610E-2 4 194
9 1296 DN Androsterone [53-41-8]; Down 200; 13.8uM; HL60; HT HG-U133A Broad Institute CMAP Down 4.822E-6 1.370E-3 1.193E-2 1.643E-2 4 195
10 1071 UP rosiglitazone; Up 200; 10uM; MCF7; HT HG-U133A EA Broad Institute CMAP Up 5.021E-6 1.370E-3 1.193E-2 1.711E-2 4 197
11 1587 DN Practolol [6673-35-4]; Down 200; 15uM; HL60; HG-U133A Broad Institute CMAP Down 5.021E-6 1.370E-3 1.193E-2 1.711E-2 4 197
12 1553 DN Oxytetracycline dihydrate [6153-64-6]; Down 200; 8uM; HL60; HG-U133A Broad Institute CMAP Down 5.123E-6 1.370E-3 1.193E-2 1.745E-2 4 198
13 2769 DN Acetopromazine maleate salt [3598-37-6]; Down 200; 9uM; MCF7; HT HG-U133A Broad Institute CMAP Down 5.226E-6 1.370E-3 1.193E-2 1.781E-2 4 199
14 CID006441172 bistheonellide A Stitch 1.913E-5 4.344E-3 3.784E-2
6.517E-2
 2 11
15 CID000119538 Viroisin Stitch 1.913E-5 4.344E-3 3.784E-2
6.517E-2
 2 11
16 CID000091511 BFDGE Stitch 2.294E-5 4.886E-3 4.256E-2
7.817E-2
 2 12
17 CID005288658 kabiramide C Stitch 3.161E-5 6.092E-3
5.306E-2
1.077E-1
 2 14
18 CID006368594 AC1OC6D1 Stitch 3.218E-5 6.092E-3
5.306E-2
1.096E-1
 3 104
19 CID005459290 Nsc687160 Stitch 5.308E-5 9.184E-3
8.000E-2
1.808E-1
 2 18
20 CID000079129 m2-19 Stitch 5.930E-5 9.184E-3
8.000E-2
2.020E-1
 2 19
21 CID006440827 tolytoxin Stitch 5.930E-5 9.184E-3
8.000E-2
2.020E-1
 2 19
22 CID000074997 5'IATR Stitch 5.930E-5 9.184E-3
8.000E-2
2.020E-1
 2 19
23 CID000329495 NSC312786 Stitch 7.278E-5 9.918E-3
8.639E-2
2.479E-1
 2 21
24 CID005311323 Mgamp-pnp Stitch 7.278E-5 9.918E-3
8.639E-2
2.479E-1
 2 21
25 CID000384633 AC1L8NVR Stitch 7.278E-5 9.918E-3
8.639E-2
2.479E-1
 2 21
26 CID003496889 Amphoterin Stitch 7.643E-5 9.920E-3
8.641E-2
2.604E-1
 3 139
27 CID004682184 Nbd-Ph Stitch 9.555E-5 9.920E-3
8.641E-2
3.255E-1
 2 24
28 CID005288653 CID5288653 Stitch 1.307E-4 9.920E-3
8.641E-2
4.452E-1
 2 28
29 CID006451158 azaspiracid Stitch 1.503E-4 9.920E-3
8.641E-2
5.120E-1
 2 30
30 1398 DN Dihydroergotamine tartrate [5989-77-5]; Down 200; 3uM; HL60; HG-U133A Broad Institute CMAP Down 1.617E-4 9.920E-3
8.641E-2
5.508E-1
 3 179
31 ctd:C070081 fulvestrant CTD 1.711E-4 9.920E-3
8.641E-2
5.828E-1
 4 486
32 CID000004267 AC1L1HS4 Stitch 1.712E-4 9.920E-3
8.641E-2
5.834E-1
 2 32
33 6750 DN Hesperetin [520-33-2]; Down 200; 13.2uM; PC3; HT HG-U133A Broad Institute CMAP Down 1.898E-4 9.920E-3
8.641E-2
6.466E-1
 3 189
34 3144 DN Deptropine citrate [2169-75-7]; Down 200; 7.6uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.928E-4 9.920E-3
8.641E-2
6.567E-1
 3 190
35 CID000122690 astragaloside A Stitch 1.935E-4 9.920E-3
8.641E-2
6.594E-1
 2 34
36 CID000076765 N,N'-p-phenylenedimaleimide Stitch 1.935E-4 9.920E-3
8.641E-2
6.594E-1
 2 34
37 CID000001312 1,N6-ethenoadenosine 5'-diphosphate Stitch 1.935E-4 9.920E-3
8.641E-2
6.594E-1
 2 34
38 CID004631220 AC1NDT8D Stitch 1.935E-4 9.920E-3
8.641E-2
6.594E-1
 2 34
39 6207 DN Clotrimazole [23593-75-1]; Down 200; 11.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.988E-4 9.920E-3
8.641E-2
6.773E-1
 3 192
40 1644 DN radicicol, diheterospora chlamydosporia; Down 200; 0.1uM; MCF7; HT HG-U133A Broad Institute CMAP Down 2.019E-4 9.920E-3
8.641E-2
6.878E-1
 3 193
41 7427 DN Econazole nitrate [24169-02-6]; Down 200; 9uM; MCF7; HT HG-U133A Broad Institute CMAP Down 2.019E-4 9.920E-3
8.641E-2
6.878E-1
 3 193
42 6751 DN Ceforanide [60925-61-3]; Down 200; 7.6uM; PC3; HT HG-U133A Broad Institute CMAP Down 2.019E-4 9.920E-3
8.641E-2
6.878E-1
 3 193
43 1268 DN Carbetapentane citrate [23142-01-0]; Down 200; 7.6uM; HL60; HT HG-U133A Broad Institute CMAP Down 2.019E-4 9.920E-3
8.641E-2
6.878E-1
 3 193
44 1227 UP LY 294002; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP Up 2.019E-4 9.920E-3
8.641E-2
6.878E-1
 3 193
45 3672 DN Clemizole hydrochloride [1163-36-6]; Down 200; 11uM; PC3; HT HG-U133A Broad Institute CMAP Down 2.019E-4 9.920E-3
8.641E-2
6.878E-1
 3 193
46 2009 DN Verapamyl hydrochloride [152-11-4]; Down 200; 8.2uM; HL60; HG-U133A Broad Institute CMAP Down 2.050E-4 9.920E-3
8.641E-2
6.983E-1
 3 194
47 4848 DN Iodixanol [92339-11-2]; Down 200; 2.6uM; MCF7; HT HG-U133A Broad Institute CMAP Down 2.050E-4 9.920E-3
8.641E-2
6.983E-1
 3 194
48 5307 DN Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; MCF7; HT HG-U133A Broad Institute CMAP Down 2.081E-4 9.920E-3
8.641E-2
7.090E-1
 3 195
49 4333 DN PHA-00851261E [724719-49-7]; Down 200; 1uM; PC3; HT HG-U133A Broad Institute CMAP Down 2.081E-4 9.920E-3
8.641E-2
7.090E-1
 3 195
50 1770 DN Lobeline alpha (-) hydrochoride [134-63-4]; Down 200; 10.6uM; HL60; HG-U133A Broad Institute CMAP Down 2.112E-4 9.920E-3
8.641E-2
7.197E-1
 3 196
Show 45 more annotations

18: Disease [Display Chart] 12 input genes in category / 250 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0265338 Coffin-Siris syndrome DisGeNET Curated 3.173E-11 7.931E-9 4.839E-8 7.931E-9 5 36
2 C4024682 Hypoplastic fifth fingernail DisGeNET Curated 3.100E-9 2.583E-7 1.576E-6 7.750E-7 3 5
3 C4024507 Aplasia/Hypoplasia of the distal phalanx of the 5th finger DisGeNET Curated 3.100E-9 2.583E-7 1.576E-6 7.750E-7 3 5
4 C1868577 Patella aplasia-hypoplasia DisGeNET Curated 8.836E-8 4.455E-6 2.718E-5 2.209E-5 3 13
5 C2053437 Full lower lip DisGeNET Curated 1.069E-7 4.455E-6 2.718E-5 2.673E-5 4 64
6 C1839739 Prominent lower lip DisGeNET Curated 1.069E-7 4.455E-6 2.718E-5 2.673E-5 4 64
7 C0024433 Macrostomia DisGeNET Curated 1.825E-7 6.519E-6 3.977E-5 4.563E-5 4 73
8 C1832348 Slow-growing hair DisGeNET Curated 2.986E-7 9.332E-6 5.693E-5 7.466E-5 3 19
9 C1849211 Generalized hirsutism DisGeNET Curated 2.185E-6 5.942E-5 3.625E-4 5.462E-4 3 36
10 C1853738 Long eyelashes DisGeNET Curated 2.377E-6 5.942E-5 3.625E-4 5.942E-4 3 37
11 C4049796 Abnormality of cardiovascular system morphology DisGeNET Curated 2.793E-6 6.348E-5 3.873E-4 6.983E-4 3 39
12 C0010964 Dandy-Walker Syndrome DisGeNET Curated 3.504E-6 7.300E-5 4.454E-4 8.760E-4 3 42
13 C1853487 Bushy eyebrows DisGeNET Curated 5.607E-6 8.834E-5 5.389E-4 1.402E-3 3 49
14 C3279222 Cerebellar hypoplasia and atrophy DisGeNET Curated 5.963E-6 8.834E-5 5.389E-4 1.491E-3 3 50
15 C1839829 Short distal phalanges DisGeNET Curated 5.963E-6 8.834E-5 5.389E-4 1.491E-3 3 50
16 C1842876 Depressed nasal ridge DisGeNET Curated 6.333E-6 8.834E-5 5.389E-4 1.583E-3 3 51
17 C0021296 Infant, Small for Gestational Age DisGeNET Curated 6.360E-6 8.834E-5 5.389E-4 1.590E-3 4 177
18 C1386048 Intrauterine retardation DisGeNET Curated 6.360E-6 8.834E-5 5.389E-4 1.590E-3 4 177
19 C0015934 Fetal Growth Retardation DisGeNET Curated 7.741E-6 1.019E-4 6.214E-4 1.935E-3 4 186
20 C0262444 Dental abnormalities DisGeNET Curated 1.090E-5 1.362E-4 8.311E-4 2.725E-3 3 61
21 C0877024 Schimke immunoosseous dysplasia DisGeNET Curated 1.404E-5 1.672E-4 1.020E-3 3.510E-3 2 8
22 C0040427 Tooth Abnormalities DisGeNET Curated 1.874E-5 2.130E-4 1.299E-3 4.685E-3 3 73
23 C3553764 Joint hyperflexibility DisGeNET Curated 2.288E-5 2.486E-4 1.517E-3 5.719E-3 3 78
24 C1303073 Nicolaides Baraitser syndrome DisGeNET Curated 3.903E-5 4.066E-4 2.480E-3 9.758E-3 2 13
25 C0010417 Cryptorchidism DisGeNET Curated 5.069E-5 5.069E-4 3.092E-3 1.267E-2 4 300
26 C4072825 Thickened facial skin with coarse facial features DisGeNET Curated 6.231E-5 5.770E-4 3.520E-3 1.558E-2 3 109
27 C1845847 Coarse facial features DisGeNET Curated 6.231E-5 5.770E-4 3.520E-3 1.558E-2 3 109
28 C1845055 ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, NONDELETION TYPE, X-LINKED DisGeNET Curated 9.481E-5 8.465E-4 5.164E-3 2.370E-2 2 20
29 C0035934 Rubinstein-Taybi Syndrome DisGeNET Curated 1.152E-4 9.928E-4 6.057E-3 2.879E-2 2 22
30 C0424688 Small head DisGeNET Curated 1.206E-4 1.005E-3 6.130E-3 3.014E-2 4 375
31 C3806482 Recurrent respiratory infections DisGeNET Curated 1.485E-4 1.198E-3 7.306E-3 3.712E-2 3 146
32 C2674608 Feeding difficulties in infancy DisGeNET Curated 2.535E-4 1.981E-3 1.208E-2
6.338E-2
 3 175
33 C0010606 Adenoid Cystic Carcinoma DisGeNET Curated 3.033E-4 2.230E-3 1.361E-2
7.583E-2
 3 186
34 C0018772 Hearing Loss, Partial DisGeNET Curated 3.033E-4 2.230E-3 1.361E-2
7.583E-2
 3 186
35 C3550546 Depressed nasal root/bridge DisGeNET Curated 3.537E-4 2.390E-3 1.458E-2
8.843E-2
 3 196
36 C4280495 Concave bridge of nose DisGeNET Curated 3.537E-4 2.390E-3 1.458E-2
8.843E-2
 3 196
37 C1836542 Depressed nasal bridge DisGeNET Curated 3.537E-4 2.390E-3 1.458E-2
8.843E-2
 3 196
38 C0011053 Deafness DisGeNET Curated 3.644E-4 2.397E-3 1.463E-2
9.110E-2
 3 198
39 C1384666 hearing impairment DisGeNET Curated 3.808E-4 2.441E-3 1.489E-2
9.521E-2
 3 201
40 C0339789 Congenital deafness DisGeNET Curated 5.366E-4 3.354E-3 2.046E-2
1.341E-1
 3 226
41 C1849367 Nasal bridge wide DisGeNET Curated 6.164E-4 3.560E-3 2.172E-2
1.541E-1
 3 237
42 C1839764 Broad flat nasal bridge DisGeNET Curated 6.164E-4 3.560E-3 2.172E-2
1.541E-1
 3 237
43 cv:C2750074 Rhabdoid tumor predisposition syndrome 2 Clinical Variations 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
44 C2750074 Rhabdoid Tumor Predisposition Syndrome 2 DisGeNET Curated 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
45 cv:C1303073 Nicolaides-Baraitser syndrome Clinical Variations 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
46 cv:CN123924 Mental retardation, autosomal dominant 16 Clinical Variations 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
47 cv:CN123922 Mental retardation, autosomal dominant 14 Clinical Variations 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
48 OMIN:613325 RHABDOID TUMOR PREDISPOSITION SYNDROME 2; RTPS2 OMIM 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
49 C3553249 MENTAL RETARDATION, AUTOSOMAL DOMINANT 16 DisGeNET Curated 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
50 C3150215 CHROMOSOME 6q24-q25 DELETION SYNDROME DisGeNET Curated 7.405E-4 3.560E-3 2.172E-2
1.851E-1
 1 1
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