Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc331_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 26 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0008093 cytoskeletal adaptor activity 6.882E-6 1.565E-4 6.031E-4 1.789E-4 2 16
2 GO:0005452 inorganic anion exchanger activity 1.204E-5 1.565E-4 6.031E-4 3.130E-4 2 21
3 GO:0015301 anion:anion antiporter activity 2.325E-5 1.846E-4 7.114E-4 6.045E-4 2 29
4 GO:0030507 spectrin binding 2.840E-5 1.846E-4 7.114E-4 7.383E-4 2 32
5 GO:0099516 ion antiporter activity 8.481E-5 4.410E-4 1.700E-3 2.205E-3 2 55
6 GO:0015297 antiporter activity 1.938E-4 8.396E-4 3.236E-3 5.038E-3 2 83
7 GO:0005200 structural constituent of cytoskeleton 3.404E-4 1.264E-3 4.873E-3 8.849E-3 2 110
8 GO:0015103 inorganic anion transmembrane transporter activity 4.897E-4 1.592E-3 6.134E-3 1.273E-2 2 132
9 GO:0030674 protein binding, bridging 7.453E-4 2.153E-3 8.299E-3 1.938E-2 2 163
10 GO:0022853 active ion transmembrane transporter activity 8.584E-4 2.169E-3 8.362E-3 2.232E-2 2 175
11 GO:0060090 molecular adaptor activity 9.178E-4 2.169E-3 8.362E-3 2.386E-2 2 181
12 GO:0015291 secondary active transmembrane transporter activity 1.553E-3 3.365E-3 1.297E-2 4.038E-2 2 236
13 GO:0043495 protein membrane anchor 2.409E-3 4.542E-3 1.751E-2
6.264E-2
 1 9
14 GO:0008509 anion transmembrane transporter activity 2.446E-3 4.542E-3 1.751E-2
6.359E-2
 2 297
15 GO:0022804 active transmembrane transporter activity 3.630E-3 6.292E-3 2.425E-2
9.437E-2
 2 363
16 GO:0015106 bicarbonate transmembrane transporter activity 5.081E-3 8.257E-3 3.182E-2
1.321E-1
 1 19
17 GO:0030506 ankyrin binding 5.615E-3 8.587E-3 3.310E-2
1.460E-1
 1 21
18 GO:0045296 cadherin binding 8.546E-3 1.234E-2 4.758E-2
2.222E-1
 1 32
19 GO:0051117 ATPase binding 2.310E-2 3.161E-2
1.218E-1
6.005E-1
 1 87
20 GO:0015108 chloride transmembrane transporter activity 2.441E-2 3.173E-2
1.223E-1
6.347E-1
 1 92
21 GO:0044325 ion channel binding 3.357E-2 4.156E-2
1.602E-1
8.729E-1
 1 127
Show 16 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 184 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006814 sodium ion transport 1.555E-5 2.861E-3 1.658E-2 2.861E-3 3 218
2 GO:0010765 positive regulation of sodium ion transport 5.431E-5 3.486E-3 2.020E-2 9.993E-3 2 44
3 GO:0015701 bicarbonate transport 5.683E-5 3.486E-3 2.020E-2 1.046E-2 2 45
4 GO:0051453 regulation of intracellular pH 1.762E-4 6.488E-3 3.760E-2 3.242E-2 2 79
5 GO:0030641 regulation of cellular pH 1.853E-4 6.488E-3 3.760E-2 3.409E-2 2 81
6 GO:0002028 regulation of sodium ion transport 2.187E-4 6.488E-3 3.760E-2 4.025E-2 2 88
7 GO:1900827 positive regulation of membrane depolarization during cardiac muscle cell action potential 2.685E-4 6.488E-3 3.760E-2 4.940E-2 1 1
8 GO:0006885 regulation of pH 2.939E-4 6.488E-3 3.760E-2
5.407E-2
 2 102
9 GO:0030004 cellular monovalent inorganic cation homeostasis 3.174E-4 6.488E-3 3.760E-2
5.840E-2
 2 106
10 GO:0072660 maintenance of protein location in plasma membrane 5.369E-4 7.599E-3 4.404E-2
9.879E-2
 1 2
11 GO:0010650 positive regulation of cell communication by electrical coupling 5.369E-4 7.599E-3 4.404E-2
9.879E-2
 1 2
12 GO:0072658 maintenance of protein location in membrane 5.369E-4 7.599E-3 4.404E-2
9.879E-2
 1 2
13 GO:0010037 response to carbon dioxide 5.369E-4 7.599E-3 4.404E-2
9.879E-2
 1 2
14 GO:0015698 inorganic anion transport 6.684E-4 8.628E-3 5.000E-2
1.230E-1
 2 154
15 GO:0055067 monovalent inorganic cation homeostasis 7.034E-4 8.628E-3 5.000E-2
1.294E-1
 2 158
16 GO:0006888 ER to Golgi vesicle-mediated transport 8.914E-4 1.025E-2
5.941E-2
1.640E-1
 2 178
17 GO:0006612 protein targeting to membrane 1.058E-3 1.097E-2
6.360E-2
1.946E-1
 2 194
18 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential 1.074E-3 1.097E-2
6.360E-2
1.975E-1
 1 4
19 GO:0098902 regulation of membrane depolarization during action potential 1.342E-3 1.265E-2
7.331E-2
2.469E-1
 1 5
20 GO:0072659 protein localization to plasma membrane 1.419E-3 1.265E-2
7.331E-2
2.611E-1
 2 225
21 GO:1990778 protein localization to cell periphery 1.444E-3 1.265E-2
7.331E-2
2.657E-1
 2 227
22 GO:0034112 positive regulation of homotypic cell-cell adhesion 1.559E-3 1.304E-2
7.558E-2
2.869E-1
 2 236
23 GO:0071286 cellular response to magnesium ion 1.878E-3 1.503E-2
8.707E-2
3.456E-1
 1 7
24 GO:0098656 anion transmembrane transport 1.976E-3 1.515E-2
8.777E-2
3.635E-1
 2 266
25 GO:0022409 positive regulation of cell-cell adhesion 2.125E-3 1.519E-2
8.802E-2
3.910E-1
 2 276
26 GO:0045199 maintenance of epithelial cell apical/basal polarity 2.146E-3 1.519E-2
8.802E-2
3.949E-1
 1 8
27 GO:0043270 positive regulation of ion transport 2.248E-3 1.532E-2
8.877E-2
4.137E-1
 2 284
28 GO:0007009 plasma membrane organization 2.359E-3 1.532E-2
8.877E-2
4.340E-1
 2 291
29 GO:0035090 maintenance of apical/basal cell polarity 2.414E-3 1.532E-2
8.877E-2
4.442E-1
 1 9
30 GO:1903817 negative regulation of voltage-gated potassium channel activity 2.682E-3 1.592E-2
9.226E-2
4.935E-1
 1 10
31 GO:1902260 negative regulation of delayed rectifier potassium channel activity 2.682E-3 1.592E-2
9.226E-2
4.935E-1
 1 10
32 GO:0007016 cytoskeletal anchoring at plasma membrane 2.950E-3 1.696E-2
9.830E-2
5.428E-1
 1 11
33 GO:0048193 Golgi vesicle transport 3.205E-3 1.721E-2
9.971E-2
5.896E-1
 2 340
34 GO:0034110 regulation of homotypic cell-cell adhesion 3.354E-3 1.721E-2
9.971E-2
6.172E-1
 2 348
35 GO:0010649 regulation of cell communication by electrical coupling 3.486E-3 1.721E-2
9.971E-2
6.414E-1
 1 13
36 GO:1904181 positive regulation of membrane depolarization 3.486E-3 1.721E-2
9.971E-2
6.414E-1
 1 13
37 GO:0010960 magnesium ion homeostasis 3.486E-3 1.721E-2
9.971E-2
6.414E-1
 1 13
38 GO:0030011 maintenance of cell polarity 3.754E-3 1.721E-2
9.971E-2
6.907E-1
 1 14
39 GO:0045838 positive regulation of membrane potential 3.754E-3 1.721E-2
9.971E-2
6.907E-1
 1 14
40 GO:0010959 regulation of metal ion transport 3.864E-3 1.721E-2
9.971E-2
7.110E-1
 2 374
41 GO:0090150 establishment of protein localization to membrane 3.925E-3 1.721E-2
9.971E-2
7.223E-1
 2 377
42 GO:2000651 positive regulation of sodium ion transmembrane transporter activity 4.021E-3 1.721E-2
9.971E-2
7.399E-1
 1 15
43 GO:0045760 positive regulation of action potential 4.021E-3 1.721E-2
9.971E-2
7.399E-1
 1 15
44 GO:0034109 homotypic cell-cell adhesion 4.452E-3 1.862E-2
1.079E-1
8.191E-1
 2 402
45 GO:0086012 membrane depolarization during cardiac muscle cell action potential 4.824E-3 1.912E-2
1.108E-1
8.876E-1
 1 18
46 GO:1901017 negative regulation of potassium ion transmembrane transporter activity 4.824E-3 1.912E-2
1.108E-1
8.876E-1
 1 18
47 GO:0045785 positive regulation of cell adhesion 4.964E-3 1.912E-2
1.108E-1
9.134E-1
 2 425
48 GO:0022407 regulation of cell-cell adhesion 5.079E-3 1.912E-2
1.108E-1
9.345E-1
 2 430
49 GO:1902259 regulation of delayed rectifier potassium channel activity 5.091E-3 1.912E-2
1.108E-1
9.368E-1
 1 19
50 GO:0098901 regulation of cardiac muscle cell action potential 5.359E-3 1.933E-2
1.120E-1
9.860E-1
 1 20
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 49 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0014731 spectrin-associated cytoskeleton 1.540E-6 5.617E-5 2.516E-4 7.548E-5 2 8
2 GO:0030018 Z disc 2.351E-6 5.617E-5 2.516E-4 1.152E-4 3 119
3 GO:0031674 I band 3.439E-6 5.617E-5 2.516E-4 1.685E-4 3 135
4 GO:0030017 sarcomere 1.087E-5 1.218E-4 5.454E-4 5.328E-4 3 198
5 GO:0044449 contractile fiber part 1.392E-5 1.218E-4 5.454E-4 6.820E-4 3 215
6 GO:0030016 myofibril 1.491E-5 1.218E-4 5.454E-4 7.306E-4 3 220
7 GO:0043292 contractile fiber 1.794E-5 1.245E-4 5.578E-4 8.789E-4 3 234
8 GO:0016323 basolateral plasma membrane 2.033E-5 1.245E-4 5.578E-4 9.962E-4 3 244
9 GO:0014704 intercalated disc 9.046E-5 4.925E-4 2.206E-3 4.433E-3 2 58
10 GO:0016529 sarcoplasmic reticulum 1.173E-4 5.562E-4 2.491E-3 5.747E-3 2 66
11 GO:0044291 cell-cell contact zone 1.358E-4 5.562E-4 2.491E-3 6.655E-3 2 71
12 GO:0044304 main axon 1.476E-4 5.562E-4 2.491E-3 7.231E-3 2 74
13 GO:0016528 sarcoplasm 1.476E-4 5.562E-4 2.491E-3 7.231E-3 2 74
14 GO:0030863 cortical cytoskeleton 2.538E-4 8.882E-4 3.978E-3 1.243E-2 2 97
15 GO:0044448 cell cortex part 5.130E-4 1.676E-3 7.506E-3 2.514E-2 2 138
16 GO:0042383 sarcolemma 6.219E-4 1.904E-3 8.531E-3 3.047E-2 2 152
17 GO:0045211 postsynaptic membrane 1.355E-3 3.906E-3 1.750E-2
6.640E-2
 2 225
18 GO:0005938 cell cortex 1.887E-3 5.137E-3 2.301E-2
9.247E-2
 2 266
19 GO:0097060 synaptic membrane 2.361E-3 6.090E-3 2.728E-2
1.157E-1
 2 298
20 GO:0033267 axon part 2.536E-3 6.214E-3 2.783E-2
1.243E-1
 2 309
21 GO:0099568 cytoplasmic region 2.801E-3 6.537E-3 2.928E-2
1.373E-1
 2 325
22 GO:0043194 axon initial segment 3.406E-3 7.586E-3 3.398E-2
1.669E-1
 1 13
23 GO:0033270 paranode region of axon 3.929E-3 8.370E-3 3.749E-2
1.925E-1
 1 15
24 GO:0033268 node of Ranvier 4.190E-3 8.556E-3 3.832E-2
2.053E-1
 1 16
25 GO:0005911 cell-cell junction 4.592E-3 9.000E-3 4.031E-2
2.250E-1
 2 418
26 GO:0030673 axolemma 4.975E-3 9.375E-3 4.199E-2
2.438E-1
 1 19
27 GO:0098794 postsynapse 5.282E-3 9.585E-3 4.293E-2
2.588E-1
 2 449
28 GO:0043034 costamere 5.497E-3 9.620E-3 4.309E-2
2.694E-1
 1 21
29 GO:0031430 M band 6.019E-3 1.017E-2 4.556E-2
2.949E-1
 1 23
30 GO:0032809 neuronal cell body membrane 7.585E-3 1.199E-2
5.370E-2
3.717E-1
 1 29
31 GO:0044298 cell body membrane 7.585E-3 1.199E-2
5.370E-2
3.717E-1
 1 29
32 GO:0009925 basal plasma membrane 1.123E-2 1.667E-2
7.469E-2
5.503E-1
 1 43
33 GO:0031672 A band 1.123E-2 1.667E-2
7.469E-2
5.503E-1
 1 43
34 GO:0032589 neuron projection membrane 1.279E-2 1.843E-2
8.256E-2
6.267E-1
 1 49
35 GO:0016328 lateral plasma membrane 1.383E-2 1.936E-2
8.671E-2
6.775E-1
 1 53
36 GO:0031594 neuromuscular junction 1.564E-2 2.071E-2
9.279E-2
7.664E-1
 1 60
37 GO:0030315 T-tubule 1.564E-2 2.071E-2
9.279E-2
7.664E-1
 1 60
38 GO:0045178 basal part of cell 1.668E-2 2.151E-2
9.633E-2
8.172E-1
 1 64
39 GO:0005923 bicellular tight junction 2.981E-2 3.745E-2
1.677E-1
1.000E0
 1 115
40 GO:0070160 tight junction 3.058E-2 3.746E-2
1.678E-1
1.000E0
 1 118
41 GO:0043296 apical junction complex 3.390E-2 4.051E-2
1.815E-1
1.000E0
 1 131
42 GO:0072562 blood microparticle 3.696E-2 4.312E-2
1.931E-1
1.000E0
 1 143
43 GO:0031256 leading edge membrane 3.874E-2 4.414E-2
1.977E-1
1.000E0
 1 150
44 GO:0031225 anchored component of membrane 4.128E-2 4.597E-2
2.059E-1
1.000E0
 1 160
Show 39 more annotations

4: Human Phenotype [Display Chart] 4 input genes in category / 183 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0004835 Microspherocytosis 1.136E-5 1.386E-3 8.022E-3 2.079E-3 2 7
2 HP:0004839 Pyropoikilocytosis 1.514E-5 1.386E-3 8.022E-3 2.771E-3 2 8
3 HP:0004445 Elliptocytosis 4.212E-5 2.248E-3 1.301E-2 7.709E-3 2 13
4 HP:0004446 Stomatocytosis 4.913E-5 2.248E-3 1.301E-2 8.991E-3 2 14
5 HP:0008341 Distal renal tubular acidosis 7.336E-5 2.685E-3 1.555E-2 1.343E-2 2 17
6 HP:0001889 Megaloblastic anemia 1.362E-4 4.155E-3 2.406E-2 2.493E-2 2 23
7 HP:0001748 Polysplenia 1.615E-4 4.221E-3 2.444E-2 2.955E-2 2 25
8 HP:0009799 Supernumerary spleens 4.393E-4 9.587E-3
5.550E-2
8.040E-2
 2 41
9 HP:0004804 Congenital hemolytic anemia 5.064E-4 9.587E-3
5.550E-2
9.267E-2
 2 44
10 HP:0004810 Congenital hypoplastic anemia 5.298E-4 9.587E-3
5.550E-2
9.695E-2
 2 45
11 HP:0004870 Chronic hemolytic anemia 6.031E-4 9.587E-3
5.550E-2
1.104E-1
 2 48
12 HP:0004444 Spherocytosis 6.286E-4 9.587E-3
5.550E-2
1.150E-1
 2 49
13 HP:0030036 Isothenuria 8.498E-4 1.196E-2
6.926E-2
1.555E-1
 1 1
14 HP:0001978 Extramedullary hematopoiesis 1.073E-3 1.403E-2
8.120E-2
1.964E-1
 2 64
15 HP:0001923 Reticulocytosis 1.512E-3 1.775E-2
1.027E-1
2.767E-1
 2 76
16 HP:0001972 Macrocytic anemia 1.552E-3 1.775E-2
1.027E-1
2.839E-1
 2 77
17 HP:0001908 Hypoplastic anemia 1.801E-3 1.939E-2
1.123E-1
3.297E-1
 2 83
18 HP:0005502 Increased red cell osmotic fragility 2.548E-3 2.318E-2
1.342E-1
4.662E-1
 1 3
19 HP:0025409 Abnormal spleen physiology 2.608E-3 2.318E-2
1.342E-1
4.772E-1
 2 100
20 HP:0001971 Hypersplenism 2.608E-3 2.318E-2
1.342E-1
4.772E-1
 2 100
21 HP:0004312 Abnormality of reticulocytes 2.660E-3 2.318E-2
1.342E-1
4.867E-1
 2 101
22 HP:0001900 Increased hemoglobin 2.927E-3 2.434E-2
1.409E-1
5.356E-1
 2 106
23 HP:0001081 Cholelithiasis 3.321E-3 2.643E-2
1.530E-1
6.078E-1
 2 113
24 HP:0005560 Imbalanced hemoglobin synthesis 3.498E-3 2.667E-2
1.544E-1
6.401E-1
 2 116
25 HP:0001947 Renal tubular acidosis 3.679E-3 2.693E-2
1.559E-1
6.732E-1
 2 119
26 HP:0012437 Abnormal gallbladder morphology 3.990E-3 2.791E-2
1.616E-1
7.301E-1
 2 124
27 HP:0001890 Autoimmune hemolytic anemia 4.118E-3 2.791E-2
1.616E-1
7.535E-1
 2 126
28 HP:0011902 Abnormal hemoglobin 4.379E-3 2.862E-2
1.657E-1
8.014E-1
 2 130
29 HP:0001973 Autoimmune thrombocytopenia 4.996E-3 3.153E-2
1.825E-1
9.143E-1
 2 139
30 HP:0000124 Renal tubular dysfunction 5.211E-3 3.178E-2
1.840E-1
9.535E-1
 2 142
31 HP:0002904 Hyperbilirubinemia 5.503E-3 3.248E-2
1.881E-1
1.000E0
 2 146
32 HP:0005264 Abnormality of the gallbladder 5.803E-3 3.319E-2
1.921E-1
1.000E0
 2 150
33 HP:0000979 Purpura 6.748E-3 3.547E-2
2.053E-1
1.000E0
 2 162
34 HP:0004918 Hyperchloremic metabolic acidosis 6.783E-3 3.547E-2
2.053E-1
1.000E0
 1 8
35 HP:0025066 Decreased mean corpuscular volume 6.783E-3 3.547E-2
2.053E-1
1.000E0
 1 8
36 HP:0008153 Periodic hypokalemic paresis 7.629E-3 3.674E-2
2.127E-1
1.000E0
 1 9
37 HP:0001995 Hyperchloremic acidosis 7.629E-3 3.674E-2
2.127E-1
1.000E0
 1 9
38 HP:0003763 Bruxism 7.629E-3 3.674E-2
2.127E-1
1.000E0
 1 9
39 HP:0004447 Poikilocytosis 8.384E-3 3.934E-2
2.277E-1
1.000E0
 2 181
40 HP:0001901 Polycythemia 8.842E-3 4.045E-2
2.342E-1
1.000E0
 2 186
41 HP:0010972 Anemia of inadequate production 9.311E-3 4.156E-2
2.406E-1
1.000E0
 2 191
Show 36 more annotations

5: Mouse Phenotype [Display Chart] 5 input genes in category / 306 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0010074 stomatocytosis 1.864E-6 4.278E-4 2.696E-3 5.705E-4 2 5
2 MP:0002814 hyperchromasia 2.796E-6 4.278E-4 2.696E-3 8.556E-4 2 6
3 MP:0002812 spherocytosis 2.232E-5 1.708E-3 1.076E-2 6.831E-3 2 16
4 MP:0002594 low mean erythrocyte cell number 2.232E-5 1.708E-3 1.076E-2 6.831E-3 2 16
5 MP:0002813 microcytosis 5.127E-5 3.138E-3 1.977E-2 1.569E-2 2 24
6 MP:0002810 microcytic anemia 9.199E-5 3.264E-3 2.057E-2 2.815E-2 2 32
7 MP:0003657 abnormal erythrocyte osmotic lysis 9.790E-5 3.264E-3 2.057E-2 2.996E-2 2 33
8 MP:0005097 polychromatophilia 1.040E-4 3.264E-3 2.057E-2 3.183E-2 2 34
9 MP:0010163 hemolysis 1.168E-4 3.264E-3 2.057E-2 3.573E-2 2 36
10 MP:0001585 hemolytic anemia 1.168E-4 3.264E-3 2.057E-2 3.573E-2 2 36
11 MP:0000877 abnormal Purkinje cell morphology 1.173E-4 3.264E-3 2.057E-2 3.590E-2 3 239
12 MP:0002643 poikilocytosis 1.444E-4 3.683E-3 2.321E-2 4.420E-2 2 40
13 MP:0000875 abnormal cerebellar Purkinje cell layer 1.631E-4 3.823E-3 2.410E-2 4.992E-2 3 267
14 MP:0009395 increased nucleated erythrocyte cell number 1.831E-4 3.823E-3 2.410E-2
5.604E-2
 2 45
15 MP:0012397 abnormal nucleated erythrocyte cell number 1.999E-4 3.823E-3 2.410E-2
6.117E-2
 2 47
16 MP:0011176 abnormal erythroblast morphology 1.999E-4 3.823E-3 2.410E-2
6.117E-2
 2 47
17 MP:0003656 abnormal erythrocyte physiology 2.843E-4 5.117E-3 3.225E-2
8.699E-2
 2 56
18 MP:0009956 abnormal cerebellar layer morphology 3.086E-4 5.246E-3 3.306E-2
9.442E-2
 3 331
19 MP:0004097 abnormal cerebellar cortex morphology 4.358E-4 7.019E-3 4.423E-2
1.334E-1
 3 372
20 MP:0014085 stomach non-glandular epithelium hyperkeratosis 4.829E-4 7.388E-3 4.656E-2
1.478E-1
 1 1
21 MP:0000889 abnormal cerebellar molecular layer 5.379E-4 7.839E-3 4.940E-2
1.646E-1
 2 77
22 MP:0002416 abnormal proerythroblast morphology 6.249E-4 8.517E-3
5.368E-2
1.912E-1
 2 83
23 MP:0000876 Purkinje cell degeneration 6.553E-4 8.517E-3
5.368E-2
2.005E-1
 2 85
24 MP:0002136 abnormal kidney physiology 6.680E-4 8.517E-3
5.368E-2
2.044E-1
 3 430
25 MP:0011101 prenatal lethality, incomplete penetrance 7.005E-4 8.574E-3
5.404E-2
2.144E-1
 3 437
26 MP:0002640 reticulocytosis 8.180E-4 9.628E-3
6.068E-2
2.503E-1
 2 95
27 MP:0000849 abnormal cerebellum morphology 8.785E-4 9.956E-3
6.275E-2
2.688E-1
 3 472
28 MP:0009512 abnormal cerebellar Golgi cell morphology 9.655E-4 1.055E-2
6.650E-2
2.955E-1
 1 2
29 MP:0011913 abnormal reticulocyte cell number 1.095E-3 1.156E-2
7.283E-2
3.351E-1
 2 110
30 MP:0002424 abnormal reticulocyte morphology 1.217E-3 1.241E-2
7.824E-2
3.724E-1
 2 116
31 MP:0008801 abnormal erythroid progenitor cell morphology 1.302E-3 1.285E-2
8.099E-2
3.983E-1
 2 120
32 MP:0002591 decreased mean corpuscular volume 1.480E-3 1.415E-2
8.917E-2
4.528E-1
 2 128
33 MP:0003332 liver abscess 1.930E-3 1.737E-2
1.095E-1
5.907E-1
 1 4
34 MP:0009411 abnormal skeletal muscle fiber triad morphology 1.930E-3 1.737E-2
1.095E-1
5.907E-1
 1 4
35 MP:0010732 abnormal node of Ranvier morphology 2.412E-3 1.998E-2
1.259E-1
7.382E-1
 1 5
36 MP:0000472 abnormal stomach non-glandular epithelium morphology 2.412E-3 1.998E-2
1.259E-1
7.382E-1
 1 5
37 MP:0000852 small cerebellum 2.416E-3 1.998E-2
1.259E-1
7.393E-1
 2 164
38 MP:0010733 abnormal axon initial segment morphology 2.894E-3 2.214E-2
1.395E-1
8.857E-1
 1 6
39 MP:0005096 erythroblastosis 2.894E-3 2.214E-2
1.395E-1
8.857E-1
 1 6
40 MP:0008850 increased hemoglobin concentration distribution width 2.894E-3 2.214E-2
1.395E-1
8.857E-1
 1 6
41 MP:0005565 increased blood urea nitrogen level 3.297E-3 2.296E-2
1.447E-1
1.000E0
 2 192
42 MP:0010735 abnormal paranodal axoglial junction morphology 3.376E-3 2.296E-2
1.447E-1
1.000E0
 1 7
43 MP:0008849 abnormal hemoglobin concentration distribution width 3.376E-3 2.296E-2
1.447E-1
1.000E0
 1 7
44 MP:0010035 increased erythrocyte clearance 3.376E-3 2.296E-2
1.447E-1
1.000E0
 1 7
45 MP:0010034 abnormal erythrocyte clearance 3.376E-3 2.296E-2
1.447E-1
1.000E0
 1 7
46 MP:0000208 decreased hematocrit 3.607E-3 2.315E-2
1.459E-1
1.000E0
 2 201
47 MP:0002874 decreased hemoglobin content 3.750E-3 2.315E-2
1.459E-1
1.000E0
 2 205
48 MP:0000216 absent erythroid progenitor cell 3.858E-3 2.315E-2
1.459E-1
1.000E0
 1 8
49 MP:0003030 acidemia 3.858E-3 2.315E-2
1.459E-1
1.000E0
 1 8
50 MP:0003708 binucleate 3.858E-3 2.315E-2
1.459E-1
1.000E0
 1 8
Show 45 more annotations

6: Domain [Display Chart] 5 input genes in category / 44 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS00219 ANION EXCHANGER 1 PROSITE 1.196E-6 9.394E-6 4.108E-5 5.262E-5 2 7
2 PS00220 ANION EXCHANGER 2 PROSITE 1.196E-6 9.394E-6 4.108E-5 5.262E-5 2 7
3 PF07565 Band 3 cyto Pfam 2.050E-6 9.394E-6 4.108E-5 9.019E-5 2 9
4 3.40.1100.10 - Gene3D 2.050E-6 9.394E-6 4.108E-5 9.019E-5 2 9
5 SM00218 ZU5 SMART 2.050E-6 9.394E-6 4.108E-5 9.019E-5 2 9
6 IPR013769 Band3 cytoplasmic dom InterPro 2.050E-6 9.394E-6 4.108E-5 9.019E-5 2 9
7 IPR011531 HCO3 transpt C InterPro 2.562E-6 9.394E-6 4.108E-5 1.127E-4 2 10
8 PS51145 ZU5 PROSITE 2.562E-6 9.394E-6 4.108E-5 1.127E-4 2 10
9 PF13606 Ank 3 Pfam 2.562E-6 9.394E-6 4.108E-5 1.127E-4 2 10
10 IPR016152 PTrfase/Anion transptr InterPro 2.562E-6 9.394E-6 4.108E-5 1.127E-4 2 10
11 IPR003020 HCO3 transpt euk InterPro 2.562E-6 9.394E-6 4.108E-5 1.127E-4 2 10
12 PF00955 HCO3 cotransp Pfam 2.562E-6 9.394E-6 4.108E-5 1.127E-4 2 10
13 PF00791 ZU5 Pfam 3.757E-6 1.181E-5 5.163E-5 1.653E-4 2 12
14 IPR000906 ZU5 dom InterPro 3.757E-6 1.181E-5 5.163E-5 1.653E-4 2 12
15 SM00005 DEATH SMART 1.995E-5 5.851E-5 2.559E-4 8.777E-4 2 27
16 PF00531 Death Pfam 2.999E-5 8.247E-5 3.606E-4 1.319E-3 2 33
17 PS50017 DEATH DOMAIN PROSITE 3.991E-5 9.755E-5 4.265E-4 1.756E-3 2 38
18 IPR000488 Death domain InterPro 3.991E-5 9.755E-5 4.265E-4 1.756E-3 2 38
19 1.10.533.10 - Gene3D 2.414E-4 5.471E-4 2.393E-3 1.062E-2 2 93
20 IPR002977 Anion exchange 1 InterPro 2.669E-4 5.471E-4 2.393E-3 1.174E-2 1 1
21 IPR032991 Contactin-1 InterPro 2.669E-4 5.471E-4 2.393E-3 1.174E-2 1 1
22 IPR011029 DEATH-like dom InterPro 2.736E-4 5.471E-4 2.393E-3 1.204E-2 2 99
23 IPR018241 Anion exchange CS InterPro 8.005E-4 1.531E-3 6.696E-3 3.522E-2 1 3
24 PF12796 Ank 2 Pfam 1.281E-3 2.257E-3 9.870E-3
5.638E-2
 2 215
25 IPR003024 Na/HCO3 transpt InterPro 1.334E-3 2.257E-3 9.870E-3
5.869E-2
 1 5
26 IPR001717 Anion exchange InterPro 1.334E-3 2.257E-3 9.870E-3
5.869E-2
 1 5
27 PF00023 Ank Pfam 1.477E-3 2.407E-3 1.053E-2
6.499E-2
 2 231
28 1.25.40.20 - Gene3D 1.700E-3 2.508E-3 1.097E-2
7.480E-2
 2 248
29 SM00248 ANK SMART 1.782E-3 2.508E-3 1.097E-2
7.841E-2
 2 254
30 PS50088 ANK REPEAT PROSITE 1.810E-3 2.508E-3 1.097E-2
7.964E-2
 2 256
31 PS50297 ANK REP REGION PROSITE 1.824E-3 2.508E-3 1.097E-2
8.026E-2
 2 257
32 IPR020683 Ankyrin rpt-contain dom InterPro 1.824E-3 2.508E-3 1.097E-2
8.026E-2
 2 257
33 IPR002110 Ankyrin rpt InterPro 1.938E-3 2.584E-3 1.130E-2
8.527E-2
 2 265
Show 28 more annotations

7: Pathway [Display Chart] 5 input genes in category / 24 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1270328 Neurofascin interactions BioSystems: REACTOME 2.708E-6 4.639E-5 1.752E-4 6.498E-5 2 7
2 1270323 L1CAM interactions BioSystems: REACTOME 5.276E-6 4.639E-5 1.752E-4 1.266E-4 3 102
3 1269909 Bicarbonate transporters BioSystems: REACTOME 5.799E-6 4.639E-5 1.752E-4 1.392E-4 2 10
4 1270325 Interaction between L1 and Ankyrins BioSystems: REACTOME 5.588E-5 3.353E-4 1.266E-3 1.341E-3 2 30
5 1339109 COPI-mediated anterograde transport BioSystems: REACTOME 3.927E-4 1.885E-3 7.117E-3 9.424E-3 2 79
6 1269908 Transport of inorganic cations/anions and amino acids/oligopeptides BioSystems: REACTOME 7.195E-4 2.878E-3 1.087E-2 1.727E-2 2 107
7 1268726 ER to Golgi Anterograde Transport BioSystems: REACTOME 1.126E-3 3.859E-3 1.457E-2 2.702E-2 2 134
8 1268725 Transport to the Golgi and subsequent modification BioSystems: REACTOME 1.701E-3 5.102E-3 1.926E-2 4.082E-2 2 165
9 782000 Proteoglycans in cancer BioSystems: KEGG 2.561E-3 6.740E-3 2.545E-2
6.147E-2
 2 203
10 1270329 NrCAM interactions BioSystems: REACTOME 2.809E-3 6.740E-3 2.545E-2
6.740E-2
 1 7
11 1270225 Erythrocytes take up oxygen and release carbon dioxide BioSystems: REACTOME 3.610E-3 7.220E-3 2.726E-2
8.664E-2
 1 9
12 1270327 CHL1 interactions BioSystems: REACTOME 3.610E-3 7.220E-3 2.726E-2
8.664E-2
 1 9
13 1268714 Asparagine N-linked glycosylation BioSystems: REACTOME 4.989E-3 7.816E-3 2.951E-2
1.197E-1
 2 285
14 1269907 SLC-mediated transmembrane transport BioSystems: REACTOME 5.058E-3 7.816E-3 2.951E-2
1.214E-1
 2 287
15 1270224 Erythrocytes take up carbon dioxide and release oxygen BioSystems: REACTOME 5.211E-3 7.816E-3 2.951E-2
1.251E-1
 1 13
16 1270223 O2/CO2 exchange in erythrocytes BioSystems: REACTOME 5.211E-3 7.816E-3 2.951E-2
1.251E-1
 1 13
17 1269539 NOTCH2 Activation and Transmission of Signal to the Nucleus BioSystems: REACTOME 8.407E-3 1.187E-2 4.481E-2
2.018E-1
 1 21
18 147586 Collecting duct acid secretion BioSystems: KEGG 1.080E-2 1.440E-2
5.436E-2
2.592E-1
 1 27
19 1269536 Activated NOTCH1 Transmits Signal to the Nucleus BioSystems: REACTOME 1.239E-2 1.565E-2
5.910E-2
2.974E-1
 1 31
20 1269538 Signaling by NOTCH2 BioSystems: REACTOME 1.319E-2 1.582E-2
5.974E-2
3.164E-1
 1 33
21 169345 Notch signaling pathway BioSystems: Pathway Interaction Database 2.308E-2 2.638E-2
9.960E-2
5.539E-1
 1 58
22 1269535 Signaling by NOTCH1 BioSystems: REACTOME 2.937E-2 3.204E-2
1.210E-1
7.049E-1
 1 74
23 1269530 Signaling by NOTCH BioSystems: REACTOME 4.457E-2 4.651E-2
1.756E-1
1.000E0
 1 113
Show 18 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 781 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 24758720 Automated structure refinement for a protein heterodimer complex using limited EPR spectroscopic data and a rigid-body docking algorithm: a three-dimensional model for an ankyrin-CDB3 complex. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
2 8640229 Ankyrin-1 mutations are a major cause of dominant and recessive hereditary spherocytosis. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
3 17128827 [Polymorphism analysis of G199A, Ncol in ANK1 and Memphis I in SLC4A1 genes in Mexican healthy individuals and subjects affected with hereditary spherocytosis]. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
4 23013433 Oxygen regulates the band 3-ankyrin bridge in the human erythrocyte membrane. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
5 16762928 Rate of rupture and reattachment of the band 3-ankyrin bridge on the human erythrocyte membrane. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
6 6449514 Reassociation of ankyrin with band 3 in erythrocyte membranes and in lipid vesicles. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
7 27989623 Full-Length Anion Exchanger 1 Structure and Interactions with Ankyrin-1 Determined by Zero Length Crosslinking of Erythrocyte Membranes. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
8 21493712 Determination of structural models of the complex between the cytoplasmic domain of erythrocyte band 3 and ankyrin-R repeats 13-24. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
9 22226968 Ankyrin and band 3 differentially affect expression of membrane glycoproteins but are not required for erythroblast enucleation. Pubmed 1.371E-8 1.190E-6 8.612E-6 1.071E-5 2 2
10 10893266 Ankyrin-Tiam1 interaction promotes Rac1 signaling and metastatic breast tumor cell invasion and migration. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
11 8227202 Association of the brain anion exchanger, AE3, with the repeat domain of ankyrin. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
12 25616663 Evidence of a structural and functional ammonium transporter RhBG·anion exchanger 1·ankyrin-G complex in kidney epithelial cells. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
13 16718373 Associations of protein 4.2 with band 3 and ankyrin. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
14 18768923 Ankyrin facilitates intracellular trafficking of alpha1-Na+-K+-ATPase in polarized cells. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
15 18698006 Characterization of glycolytic enzyme interactions with murine erythrocyte membranes in wild-type and membrane protein knockout mice. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
16 25362473 A hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of Ranvier. Pubmed 4.113E-8 2.008E-6 1.453E-5 3.212E-5 2 3
17 379653 The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranes. Pubmed 8.226E-8 3.059E-6 2.214E-5 6.424E-5 2 4
18 14761957 Sodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrin. Pubmed 8.226E-8 3.059E-6 2.214E-5 6.424E-5 2 4
19 23610411 Renal intercalated cells are rather energized by a proton than a sodium pump. Pubmed 8.226E-8 3.059E-6 2.214E-5 6.424E-5 2 4
20 22147703 Analysis of the mobilities of band 3 populations associated with ankyrin protein and junctional complexes in intact murine erythrocytes. Pubmed 8.226E-8 3.059E-6 2.214E-5 6.424E-5 2 4
21 10772878 Erythroid phosphatidyl serine exposure is not predictive of thrombotic risk in mice with hemolytic anemia. Pubmed 8.226E-8 3.059E-6 2.214E-5 6.424E-5 2 4
22 16728274 Major erythrocyte membrane protein genes in EKLF-deficient mice. Pubmed 1.371E-7 4.867E-6 3.523E-5 1.071E-4 2 5
23 27848995 A novel ENU-induced ankyrin-1 mutation impairs parasite invasion and increases erythrocyte clearance during malaria infection in mice. Pubmed 2.056E-7 6.691E-6 4.843E-5 1.606E-4 2 6
24 7495297 Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice. Pubmed 2.056E-7 6.691E-6 4.843E-5 1.606E-4 2 6
25 2968981 Associations of human erythrocyte band 4.2. Binding to ankyrin and to the cytoplasmic domain of band 3. Pubmed 2.879E-7 8.993E-6 6.509E-5 2.248E-4 2 7
26 7615634 Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain. Pubmed 3.838E-7 1.153E-5 8.345E-5 2.997E-4 2 8
27 22159418 Cell organization, growth, and neural and cardiac development require αII-spectrin. Pubmed 4.934E-7 1.427E-5 1.033E-4 3.854E-4 2 9
28 19521566 The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease. Pubmed 1.446E-6 4.034E-5 2.920E-4 1.130E-3 3 202
29 18723693 Targeted deletion of alpha-adducin results in absent beta- and gamma-adducin, compensated hemolytic anemia, and lethal hydrocephalus in mice. Pubmed 2.603E-6 7.009E-5 5.074E-4 2.033E-3 2 20
30 25917818 Exome sequencing reveals pathogenic mutations in 91 strains of mice with Mendelian disorders. Pubmed 2.843E-5 2.575E-4 1.864E-3 2.220E-2 2 65
31 23255290 Hereditary spherocytosis due to band 3 deficiency: 15 novel mutations in SLC4A1. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
32 16849697 Expression and interaction of two compound heterozygous distal renal tubular acidosis mutants of kidney anion exchanger 1 in epithelial cells. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
33 24361380 Genetic modulation of working memory deficits by ankyrin 3 gene in schizophrenia. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
34 17027918 Trafficking defect of mutant kidney anion exchanger 1 (kAE1) proteins associated with distal renal tubular acidosis and Southeast Asian ovalocytosis. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
35 23390136 Homozygous and heterozygous disruptions of ANK3: at the crossroads of neurodevelopmental and psychiatric disorders. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
36 8841202 Targeted disruption of the murine erythroid band 3 gene results in spherocytosis and severe haemolytic anaemia despite a normal membrane skeleton. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
37 8578746 Blood group terminology 1995. ISBT Working Party on terminology for red cell surface antigens. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
38 15238261 Molecular mapping of the conductance activity linked to tAE1 expressed in Xenopus oocyte. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
39 20799361 Hemolytic anemia and distal renal tubular acidosis in two Indian patients homozygous for SLC4A1/AE1 mutation A858D. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
40 12832463 Variegated expression from the murine band 3 (AE1) promoter in transgenic mice is associated with mRNA transcript initiation at upstream start sites and can be suppressed by the addition of the chicken beta-globin 5' HS4 insulator element. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
41 8486643 Complex patterns of sequence variation and multiple 5' and 3' ends are found among transcripts of the erythroid ankyrin gene. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
42 9312167 Familial distal renal tubular acidosis is associated with mutations in the red cell anion exchanger (Band 3, AE1) gene. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
43 14654610 A novel mutation in the anion exchanger 1 gene is associated with familial distal renal tubular acidosis and nephrocalcinosis. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
44 1885574 Palmitoylation of cysteine 69 from the COOH-terminal of band 3 protein in the human erythrocyte membrane. Acylation occurs in the middle of the consensus sequence of F--I-IICLAVL found in band 3 protein and G2 protein of Rift Valley fever virus. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
45 7812009 Changes in the blood group Wright antigens are associated with a mutation at amino acid 658 in human erythrocyte band 3: a site of interaction between band 3 and glycophorin A under certain conditions. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
46 11556889 Mobilization of the cell adhesion glycoprotein F3/contactin to axonal surfaces is activity dependent. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
47 28494002 Involvement of Band3 in the efflux of sphingosine 1-phosphate from erythrocytes. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
48 18180363 Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
49 7579467 Decreased content of protein 4.2 in ankyrin-deficient normoblastosis (nb/nb) mouse red blood cells: evidence for ankyrin enhancement of protein 4.2 membrane binding. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
50 18775686 Effects of chronic continuous hypoxia on the expression of SLC4A8 (NDCBE) in neonatal versus adult mouse brain. Pubmed 1.309E-4 2.575E-4 1.864E-3
1.022E-1
 1 1
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 141 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:SCN1B SCN1B interactions 6.380E-7 6.296E-5 3.481E-4 8.996E-5 2 5
2 int:CHL1 CHL1 interactions 9.569E-7 6.296E-5 3.481E-4 1.349E-4 2 6
3 int:RHAG RHAG interactions 1.339E-6 6.296E-5 3.481E-4 1.889E-4 2 7
4 int:EPB42 EPB42 interactions 9.747E-6 3.072E-4 1.698E-3 1.374E-3 2 18
5 int:SLC4A1 SLC4A1 interactions 1.089E-5 3.072E-4 1.698E-3 1.536E-3 2 19
6 int:CA2 CA2 interactions 1.757E-5 4.129E-4 2.283E-3 2.477E-3 2 24
7 int:SCNN1B SCNN1B interactions 2.069E-5 4.167E-4 2.304E-3 2.917E-3 2 26
8 int:RAPGEF5 RAPGEF5 interactions 2.767E-5 4.634E-4 2.562E-3 3.902E-3 2 30
9 int:ANK1 ANK1 interactions 2.958E-5 4.634E-4 2.562E-3 4.171E-3 2 31
10 int:L1CAM L1CAM interactions 4.468E-5 6.300E-4 3.484E-3 6.300E-3 2 38
11 int:BLOC1S6 BLOC1S6 interactions 6.009E-5 7.702E-4 4.259E-3 8.472E-3 2 44
12 int:TIAM1 TIAM1 interactions 2.204E-4 2.590E-3 1.432E-2 3.108E-2 2 84
13 int:SHANK3 SHANK3 interactions 8.579E-4 9.305E-3
5.145E-2
1.210E-1
 2 166
14 int:SLC4A3 SLC4A3 interactions 1.412E-3 1.422E-2
7.861E-2
1.990E-1
 1 5
15 int:NBPF3 NBPF3 interactions 1.694E-3 1.554E-2
8.593E-2
2.388E-1
 1 6
16 int:FYN FYN interactions 1.993E-3 1.554E-2
8.593E-2
2.810E-1
 2 254
17 int:SCN2A SCN2A interactions 2.258E-3 1.554E-2
8.593E-2
3.183E-1
 1 8
18 int:MB MB interactions 2.258E-3 1.554E-2
8.593E-2
3.183E-1
 1 8
19 int:CA4 CA4 interactions 2.258E-3 1.554E-2
8.593E-2
3.183E-1
 1 8
20 int:TNC TNC interactions 2.258E-3 1.554E-2
8.593E-2
3.183E-1
 1 8
21 int:DLG4 DLG4 interactions 2.314E-3 1.554E-2
8.593E-2
3.263E-1
 2 274
22 int:FIG4 FIG4 interactions 2.540E-3 1.628E-2
9.000E-2
3.581E-1
 1 9
23 int:CNTN2 CNTN2 interactions 2.822E-3 1.730E-2
9.564E-2
3.978E-1
 1 10
24 int:KCNC1 KCNC1 interactions 3.103E-3 1.823E-2
1.008E-1
4.376E-1
 1 11
25 int:LILRB3 LILRB3 interactions 3.385E-3 1.909E-2
1.056E-1
4.773E-1
 1 12
26 int:NFASC NFASC interactions 3.948E-3 2.033E-2
1.124E-1
5.567E-1
 1 14
27 int:RYR1 RYR1 interactions 4.230E-3 2.033E-2
1.124E-1
5.964E-1
 1 15
28 int:PTPRZ1 PTPRZ1 interactions 4.511E-3 2.033E-2
1.124E-1
6.361E-1
 1 16
29 int:ADCK2 ADCK2 interactions 4.511E-3 2.033E-2
1.124E-1
6.361E-1
 1 16
30 int:ULBP2 ULBP2 interactions 4.793E-3 2.033E-2
1.124E-1
6.758E-1
 1 17
31 int:SLC12A6 SLC12A6 interactions 5.074E-3 2.033E-2
1.124E-1
7.155E-1
 1 18
32 int:MCAM MCAM interactions 5.074E-3 2.033E-2
1.124E-1
7.155E-1
 1 18
33 int:PIKFYVE PIKFYVE interactions 5.074E-3 2.033E-2
1.124E-1
7.155E-1
 1 18
34 int:PTPRB PTPRB interactions 5.074E-3 2.033E-2
1.124E-1
7.155E-1
 1 18
35 int:PALM2 PALM2 interactions 5.074E-3 2.033E-2
1.124E-1
7.155E-1
 1 18
36 int:ADCY3 ADCY3 interactions 5.355E-3 2.033E-2
1.124E-1
7.551E-1
 1 19
37 int:GPR89B GPR89B interactions 5.355E-3 2.033E-2
1.124E-1
7.551E-1
 1 19
38 int:ST7L ST7L interactions 5.637E-3 2.033E-2
1.124E-1
7.948E-1
 1 20
39 int:ABCC4 ABCC4 interactions 5.637E-3 2.033E-2
1.124E-1
7.948E-1
 1 20
40 int:MAPK6 MAPK6 interactions 5.969E-3 2.033E-2
1.124E-1
8.416E-1
 2 444
41 int:SNX14 SNX14 interactions 6.199E-3 2.033E-2
1.124E-1
8.740E-1
 1 22
42 int:OMA1 OMA1 interactions 6.199E-3 2.033E-2
1.124E-1
8.740E-1
 1 22
43 int:SPTBN4 SPTBN4 interactions 6.199E-3 2.033E-2
1.124E-1
8.740E-1
 1 22
44 int:PCNX3 PCNX3 interactions 6.761E-3 2.158E-2
1.194E-1
9.533E-1
 1 24
45 int:OBSCN OBSCN interactions 7.042E-3 2.158E-2
1.194E-1
9.929E-1
 1 25
46 int:GHDC GHDC interactions 7.042E-3 2.158E-2
1.194E-1
9.929E-1
 1 25
47 int:TNR TNR interactions 7.603E-3 2.223E-2
1.229E-1
1.000E0
 1 27
48 int:C1orf43 C1orf43 interactions 7.884E-3 2.223E-2
1.229E-1
1.000E0
 1 28
49 int:SPTB SPTB interactions 7.884E-3 2.223E-2
1.229E-1
1.000E0
 1 28
50 int:SLC4A2 SLC4A2 interactions 7.884E-3 2.223E-2
1.229E-1
1.000E0
 1 28
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 12q11-q12 12q11-q12 2.885E-4 1.442E-3 3.293E-3 1.442E-3 1 2
2 8p11.1 8p11.1 5.769E-4 1.442E-3 3.293E-3 2.885E-3 1 4
3 10q21 10q21 2.450E-3 4.083E-3 9.324E-3 1.225E-2 1 17
4 12q13.13 12q13.13 1.006E-2 1.249E-2 2.851E-2
5.029E-2
 1 70
5 17q21.31 17q21.31 1.249E-2 1.249E-2 2.851E-2
6.244E-2
 1 87

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 65 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 5 input genes in category / 8 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 403 Ankyrin repeat domain containing|BRCA1 B complex genenames.org 1.716E-3 1.373E-2 3.731E-2 1.373E-2 2 242
2 752 Solute carriers genenames.org 4.502E-3 1.801E-2 4.894E-2 3.602E-2 2 395
3 454 Blood group antigens genenames.org 1.013E-2 2.701E-2
7.340E-2
8.102E-2
 1 37

13: Coexpression [Display Chart] 5 input genes in category / 485 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M2442 Major erythrocyte membrane genes. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.919E-6 1.901E-3 1.285E-2 1.901E-3 2 15
2 M1407 Genes up-regulated after GATA1 [GeneID=2623] activation in G1E-ER4 cells (erythroid precursors engineered to express GATA1 upon addition of estradiol [PubChem=5757]). MSigDB C2: CGP Curated Gene Sets (v6.0) 8.616E-6 2.089E-3 1.413E-2 4.179E-3 2 22
3 18487511-Table1 Human StemCell Singleton08 40genes GeneSigDB 2.347E-5 3.175E-3 2.147E-2 1.138E-2 2 36
4 M3644 Genes down-regulated in pre B lymphocyte after induction of physiological DNA double-strand breaks (DSB) by RAG2 [GeneID=5897]; the changes depend on ATM [GeneID=472] but not NFKB signaling. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.618E-5 3.175E-3 2.147E-2 1.270E-2 2 38
5 M9108 Genes down-regulated in CD4 T conv: control versus over-expression of GATA1 and FOXP3 [GeneID=2623;50943]. MSigDB C7: Immunologic Signatures (v6.0) 3.853E-4 2.727E-2
1.844E-1
1.869E-1
 2 145
6 M2715 Genes down-regulated in MEF cells (embryonic fibroblasts) with knockout of SNF5 [Gene ID=6598] gene. MSigDB C6: Oncogenic Signatures (v6.0) 4.805E-4 2.727E-2
1.844E-1
2.331E-1
 2 162
7 M2741 Genes up-regulated in TIG3 cells (fibroblasts) upon knockdown of SUZ12 [Gene ID=23512] gene. MSigDB C6: Oncogenic Signatures (v6.0) 6.809E-4 2.727E-2
1.844E-1
3.302E-1
 2 193
8 M5141 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection. MSigDB C7: Immunologic Signatures (v6.0) 7.021E-4 2.727E-2
1.844E-1
3.405E-1
 2 196
9 M8345 Genes down-regulated in activated versus induced T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 7.021E-4 2.727E-2
1.844E-1
3.405E-1
 2 196
10 M4973 Genes down-regulated in comparison of B cells from influenza vaccinee pre-vaccination versus those at day 7 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 7.092E-4 2.727E-2
1.844E-1
3.440E-1
 2 197
11 M7672 Genes down-regulated in the in vitro follicular dendritic cells from peripheral lymph nodes (96h): Pam2CSK4 versus tretinoin [PubChem=444795]. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 2.727E-2
1.844E-1
3.475E-1
 2 198
12 M5945 Genes involved in metabolism of heme (a cofactor consisting of iron and porphyrin) and erythroblast differentiation. MSigDB H: Hallmark Gene Sets (v6.0) 7.309E-4 2.727E-2
1.844E-1
3.545E-1
 2 200
13 M5137 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from infanct with acute RSV infection. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.727E-2
1.844E-1
3.545E-1
 2 200
14 17464315-Table1 Human Sarcoma Nakayama07 10genes GeneSigDB 1.080E-3 3.742E-2
2.530E-1
5.239E-1
 1 5
Show 9 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 666 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Subtype iProg2 Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Subtype iProg2 Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 4.523E-5 1.606E-2
1.137E-1
 3.012E-2 3 365
2 Facebase RNAseq e10.5 Lateral Nasal Eminence 500 K1 FacebaseRNAseq e10.5 Lateral Nasal Eminence top-relative-expression-ranked 500 k-means-cluster#1 FaceBase_RNAseq 6.432E-5 1.606E-2
1.137E-1
 4.284E-2 2 56
3 Facebase RNAseq e9.5 Maxillary Arch 500 K1 FacebaseRNAseq e9.5 Maxillary Arch top-relative-expression-ranked 500 k-means-cluster#1 FaceBase_RNAseq 8.152E-5 1.606E-2
1.137E-1
5.429E-2
 2 63
4 Facebase RNAseq e10.5 Lateral Nasal Eminence 500 FacebaseRNAseq e10.5 Lateral Nasal Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 1.107E-4 1.606E-2
1.137E-1
7.372E-2
 3 493
5 Facebase RNAseq e10.5 Mandibular Arch 1000 K4 FacebaseRNAseq e10.5 Mandibular Arch top-relative-expression-ranked 1000 k-means-cluster#4 FaceBase_RNAseq 1.487E-4 1.606E-2
1.137E-1
9.904E-2
 2 85
6 Facebase RNAseq e9.5 Facial Mesenchyne 100 FacebaseRNAseq e9.5 Facial Mesenchyne top-relative-expression-ranked 100 FaceBase_RNAseq 1.898E-4 1.606E-2
1.137E-1
1.264E-1
 2 96
7 PP RBC 100 PP RBC top-relative-expression-ranked 100 PCBC 2.059E-4 1.606E-2
1.137E-1
1.371E-1
 2 100
8 Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Collecting duct (CD)/late fetal/CD b Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Collecting duct (CD)/late fetal/CD b Fetal, Development 2.291E-4 1.606E-2
1.137E-1
1.525E-1
 1 1
9 PP epoMEP 1000 K2 PP epoMEP top-relative-expression-ranked 1000 k-means-cluster#2 PCBC 2.446E-4 1.606E-2
1.137E-1
1.629E-1
 2 109
10 Facebase RNAseq e10.5 Lateral Nasal Eminence 1000 K2 FacebaseRNAseq e10.5 Lateral Nasal Eminence top-relative-expression-ranked 1000 k-means-cluster#2 FaceBase_RNAseq 3.532E-4 1.606E-2
1.137E-1
2.352E-1
 2 131
11 Facebase RNAseq e9.5 Facial Mesenchyne 500 K1 FacebaseRNAseq e9.5 Facial Mesenchyne top-relative-expression-ranked 500 k-means-cluster#1 FaceBase_RNAseq 3.586E-4 1.606E-2
1.137E-1
2.388E-1
 2 132
12 Kidney10XCellRanger Six2KI E14 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2KI E14 Eryth Eryth Overall Top 200 Genes 3.919E-4 1.606E-2
1.137E-1
2.610E-1
 2 138
13 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Overall Top 200 Genes 4.090E-4 1.606E-2
1.137E-1
2.724E-1
 2 141
14 Kidney10XCellRanger Six2TGC P0 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2TGC P0 Eryth Eryth Overall Top 200 Genes 4.266E-4 1.606E-2
1.137E-1
2.841E-1
 2 144
15 Kidney10XCellRanger Six2TGC P0 Eryth Eryth Top 200 Kidney10XCellRanger Six2TGC P0 Eryth Eryth Top 200 4.266E-4 1.606E-2
1.137E-1
2.841E-1
 2 144
16 Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Erythrocyte (ER) Human Kidney Development/Human Kidney Fetal Kidney Cell Atlas: (Tang et al 2018)/Human/Cell Subclass of Age of Cell Class of Tissue (subtype)/Erythrocyte (ER) Fetal, Development 4.445E-4 1.606E-2
1.137E-1
2.960E-1
 2 147
17 Facebase RNAseq e9.5 Facial Mesenchyne 1000 K2 FacebaseRNAseq e9.5 Facial Mesenchyne top-relative-expression-ranked 1000 k-means-cluster#2 FaceBase_RNAseq 4.505E-4 1.606E-2
1.137E-1
3.000E-1
 2 148
18 Kidney10XCellRanger Six2TGC E14 Eryth Eryth Top 200 Kidney10XCellRanger Six2TGC E14 Eryth Eryth Top 200 4.876E-4 1.606E-2
1.137E-1
3.248E-1
 2 154
19 Kidney10XCellRanger Six2TGC E14 Eryth Eryth Overall Top 200 Genes Kidney10XCellRanger Six2TGC E14 Eryth Eryth Overall Top 200 Genes 4.876E-4 1.606E-2
1.137E-1
3.248E-1
 2 154
20 Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C11-KC7 Top 200 Genes Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C11-KC7 Top 200 Genes 5.394E-4 1.606E-2
1.137E-1
3.592E-1
 2 162
21 Facebase RNAseq e9.5 Maxillary Arch 1000 K5 FacebaseRNAseq e9.5 Maxillary Arch top-relative-expression-ranked 1000 k-means-cluster#5 FaceBase_RNAseq 5.595E-4 1.606E-2
1.137E-1
3.726E-1
 2 165
22 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C7-KC1 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C7-KC1 Top 200 Genes 6.148E-4 1.606E-2
1.137E-1
4.094E-1
 2 173
23 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Polydendrocyte/Polydendrocyte/Bmp4 C1q/Tnr/Cspg8 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Polydendrocyte/Polydendrocyte/Bmp4 C1q/Tnr/Cspg8 BrainMap 7.101E-4 1.606E-2
1.137E-1
4.729E-1
 2 186
24 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal-Cortex Wilms F-U/Kidney Normal-Cortex Wilms F16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney F-U/Kidney Normal-Cortex Wilms F-U/Kidney Normal-Cortex Wilms F16 Adult, Development, and Cancer types 7.330E-4 1.606E-2
1.137E-1
4.882E-1
 2 189
25 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hDA Overall Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 7.330E-4 1.606E-2
1.137E-1
4.882E-1
 2 189
26 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iProg Overall Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 7.485E-4 1.606E-2
1.137E-1
4.985E-1
 2 191
27 Erythrocyte (ER) Erythrocyte (ER) 7.563E-4 1.606E-2
1.137E-1
5.037E-1
 2 192
28 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iNb Overall Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 7.721E-4 1.606E-2
1.137E-1
5.142E-1
 2 194
29 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 200 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Top 200 GSE76381_iPSMoleculeCountsPMLog2 7.721E-4 1.606E-2
1.137E-1
5.142E-1
 2 194
30 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iRN Overall Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 7.721E-4 1.606E-2
1.137E-1
5.142E-1
 2 194
31 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iDA Overall Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 7.721E-4 1.606E-2
1.137E-1
5.142E-1
 2 194
32 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Overall Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC iMN Overall Top 200 Genes GSE76381_iPSMoleculeCountsPMLog2 7.800E-4 1.606E-2
1.137E-1
5.195E-1
 2 195
33 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 7.960E-4 1.606E-2
1.137E-1
5.301E-1
 2 197
34 Facebase RNAseq e10.5 Mandibular Arch 2500 K2 FacebaseRNAseq e10.5 Mandibular Arch top-relative-expression-ranked 2500 k-means-cluster#2 FaceBase_RNAseq 8.615E-4 1.687E-2
1.195E-1
5.737E-1
 2 205
35 Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C12-KC7 Top 200 Genes Kidney10XCellRanger Six2KI E14 Eryth Eryth Subtype E14-Six2KI-Eryth-C12-KC7 Top 200 Genes 9.037E-4 1.688E-2
1.195E-1
6.019E-1
 2 210
36 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C6-KC1 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C6-KC1 Top 200 Genes 9.123E-4 1.688E-2
1.195E-1
6.076E-1
 2 211
37 PP RBC 500 K2 PP RBC top-relative-expression-ranked 500 k-means-cluster#2 PCBC 9.557E-4 1.693E-2
1.198E-1
6.365E-1
 2 216
38 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 2500 K3 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 2500 k-means-cluster#3 FaceBase_RNAseq 9.733E-4 1.693E-2
1.198E-1
6.482E-1
 2 218
39 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C1-KC1 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Subtype E14-Six2TGC Tsc1-Eryth-C1-KC1 Top 200 Genes 9.911E-4 1.693E-2
1.198E-1
6.601E-1
 2 220
40 Kidney10XCellRanger Six2KI E14 Eryth Eryth Top 200 Kidney10XCellRanger Six2KI E14 Eryth Eryth Top 200 1.073E-3 1.743E-2
1.234E-1
7.147E-1
 2 229
41 Facebase RNAseq ratio e10.5 MaxillaryArch vs Mandibular 2500 K1 FacebaseRNAseq ratio e10.5 MaxillaryArch vs Mandibular top-relative-expression-ranked 2500 k-means-cluster#1 FaceBase_RNAseq 1.073E-3 1.743E-2
1.234E-1
7.147E-1
 2 229
42 geo heart 2500 K1 geo heart top-relative-expression-ranked 2500 k-means-cluster#1 PCBC 1.120E-3 1.773E-2
1.255E-1
7.460E-1
 2 234
43 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Wilms tumour/Kidney Tumour Wilms Wilms tumour/Kidney Tumour Wilms T16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Wilms tumour/Kidney Tumour Wilms Wilms tumour/Kidney Tumour Wilms T16 Adult, Development, and Cancer types 1.145E-3 1.773E-2
1.255E-1
7.625E-1
 1 5
44 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Subtype UnkG Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC Unk Subtype UnkG Top 200 Genes GSE76381_EmbryoMoleculeCountsPMLog2 1.328E-3 2.010E-2
1.423E-1
8.845E-1
 2 255
45 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 Thalamus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 Thalamus Top 200 Genes BrainMap 1.370E-3 2.027E-2
1.435E-1
9.122E-1
 2 259
46 Human Cell Atlas Human Cell Atlas Erythro Erythro Subtype Erythroblast Top 200 Genes Human Cell Atlas Human Cell Atlas Erythro Erythro Subtype Erythroblast Top 200 Genes 1.598E-3 2.314E-2
1.638E-1
1.000E0
 2 280
47 gudmap developingLowerUrinaryTract e14.5 Genital tubercle 100 k2 DevelopingLowerUrinaryTract e14.5 Genital tubercle emap-6706 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.831E-3 2.504E-2
1.773E-1
1.000E0
 1 8
48 geo heart 500 K5 geo heart top-relative-expression-ranked 500 k-means-cluster#5 PCBC 1.831E-3 2.504E-2
1.773E-1
1.000E0
 1 8
49 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Excitatory Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Excitatory Top 200 Genes BrainMap 1.880E-3 2.504E-2
1.773E-1
1.000E0
 2 304
50 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Top 200 Kidney10XCellRanger Six2TGC TSC1 E14 Eryth Eryth Top 200 1.892E-3 2.504E-2
1.773E-1
1.000E0
 2 305
Show 45 more annotations

15: Computational [Display Chart] 5 input genes in category / 67 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M14349 GNF2 PCAF Neighborhood of PCAF MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.242E-4 4.548E-3 2.178E-2 8.324E-3 2 36
2 M7470 GNF2 CDC27 Neighborhood of CDC27 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.474E-4 4.548E-3 2.178E-2 2.327E-2 2 60
3 M9058 GNF2 BNIP3L Neighborhood of BNIP3L MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.464E-4 4.548E-3 2.178E-2 2.991E-2 2 68
4 M19158 GNF2 RAD23A Neighborhood of RAD23A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.596E-4 4.548E-3 2.178E-2 3.079E-2 2 69
5 M19762 GNF2 TAL1 Neighborhood of TAL1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.144E-4 4.548E-3 2.178E-2 3.447E-2 2 73
6 M11900 GNF2 ANK1 Neighborhood of ANK1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.286E-4 4.548E-3 2.178E-2 3.542E-2 2 74
7 M5633 GNF2 SPTB Neighborhood of SPTB MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.286E-4 4.548E-3 2.178E-2 3.542E-2 2 74
8 M1670 GNF2 MAP2K3 Neighborhood of MAP2K3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.430E-4 4.548E-3 2.178E-2 3.638E-2 2 75
9 M13711 GNF2 SPTA1 Neighborhood of SPTA1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.332E-4 4.714E-3 2.258E-2 4.243E-2 2 81
Show 4 more annotations

16: MicroRNA [Display Chart] 5 input genes in category / 276 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 TGCAAAC,MIR-452:MSigDB TGCAAAC,MIR-452:MSigDB MSigDB 2.087E-5 5.759E-3 3.570E-2 5.759E-3 2 105
2 hsa-miR-147:PITA hsa-miR-147:PITA TOP PITA 4.496E-5 6.204E-3 3.846E-2 1.241E-2 2 154
3 hsa-miR-10b-5p:TargetScan hsa-miR-10b-5p TargetScan 1.129E-4 7.126E-3 4.418E-2 3.115E-2 2 244
4 hsa-miR-10a-5p:TargetScan hsa-miR-10a-5p TargetScan 1.129E-4 7.126E-3 4.418E-2 3.115E-2 2 244
5 hsa-miR-1827:PITA hsa-miR-1827:PITA TOP PITA 1.291E-4 7.126E-3 4.418E-2 3.563E-2 2 261
6 hsa-miR-601:mirSVR highEffct hsa-miR-601:mirSVR nonconserved highEffect-0.5 MicroRNA.org 2.731E-4 1.256E-2
7.788E-2
7.537E-2
 2 380
7 hsa-miR-5698:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.641E-4 1.830E-2
1.134E-1
1.281E-1
 2 496
8 hsa-miR-1204:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.611E-4 2.292E-2
1.421E-1
2.101E-1
 1 11
9 hsa-miR-598-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.611E-4 2.292E-2
1.421E-1
2.101E-1
 1 11
10 hsa-miR-8088:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.303E-4 2.292E-2
1.421E-1
2.292E-1
 1 12
11 hsa-miR-6840-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.384E-3 3.280E-2
2.034E-1
3.819E-1
 1 20
12 hsa-miR-5587-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.904E-3 3.280E-2
2.034E-1
8.014E-1
 1 42
13 hsa-miR-597-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.456E-3 3.280E-2
2.034E-1
9.538E-1
 1 50
14 hsa-miR-4454:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.008E-3 3.280E-2
2.034E-1
1.000E0
 1 58
15 hsa-miR-1244:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 3.280E-2
2.034E-1
1.000E0
 1 59
16 hsa-miR-663b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.146E-3 3.280E-2
2.034E-1
1.000E0
 1 60
17 CCACACA,MIR-147:MSigDB CCACACA,MIR-147:MSigDB MSigDB 4.215E-3 3.280E-2
2.034E-1
1.000E0
 1 61
18 hsa-miR-802:Functional MTI Functional MTI miRTarbase 4.698E-3 3.280E-2
2.034E-1
1.000E0
 1 68
19 hsa-miR-503:PITA hsa-miR-503:PITA TOP PITA 4.836E-3 3.280E-2
2.034E-1
1.000E0
 1 70
20 hsa-miR-125b-1*:mirSVR highEffct hsa-miR-125b-1*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.111E-3 3.280E-2
2.034E-1
1.000E0
 1 74
21 hsa-miR-6812-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 3.280E-2
2.034E-1
1.000E0
 1 74
22 hsa-miR-1182:Functional MTI Functional MTI miRTarbase 5.180E-3 3.280E-2
2.034E-1
1.000E0
 1 75
23 hsa-miR-874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.249E-3 3.280E-2
2.034E-1
1.000E0
 1 76
24 hsa-miR-1251-5p:TargetScan hsa-miR-1251-5p TargetScan 5.456E-3 3.280E-2
2.034E-1
1.000E0
 1 79
25 hsa-miR-4304:mirSVR highEffct hsa-miR-4304:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.594E-3 3.280E-2
2.034E-1
1.000E0
 1 81
26 hsa-miR-376c-3p:Functional MTI Functional MTI miRTarbase 5.801E-3 3.280E-2
2.034E-1
1.000E0
 1 84
27 hsa-miR-613:Functional MTI Functional MTI miRTarbase 6.007E-3 3.280E-2
2.034E-1
1.000E0
 1 87
28 hsa-miR-4802-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.214E-3 3.280E-2
2.034E-1
1.000E0
 1 90
29 hsa-miR-409-5p:TargetScan hsa-miR-409-5p TargetScan 6.696E-3 3.280E-2
2.034E-1
1.000E0
 1 97
30 hsa-miR-1289:PITA hsa-miR-1289:PITA TOP PITA 6.765E-3 3.280E-2
2.034E-1
1.000E0
 1 98
31 hsa-miR-6732-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 3.280E-2
2.034E-1
1.000E0
 1 99
32 hsa-miR-7853-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.971E-3 3.280E-2
2.034E-1
1.000E0
 1 101
33 hsa-miR-3617-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.971E-3 3.280E-2
2.034E-1
1.000E0
 1 101
34 hsa-miR-621:PITA hsa-miR-621:PITA TOP PITA 6.971E-3 3.280E-2
2.034E-1
1.000E0
 1 101
35 hsa-miR-641:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.109E-3 3.280E-2
2.034E-1
1.000E0
 1 103
36 hsa-miR-574-5p:PITA hsa-miR-574-5p:PITA TOP PITA 7.315E-3 3.280E-2
2.034E-1
1.000E0
 1 106
37 hsa-miR-105-5p:Functional MTI Functional MTI miRTarbase 7.384E-3 3.280E-2
2.034E-1
1.000E0
 1 107
38 hsa-miR-3177:mirSVR highEffct hsa-miR-3177:mirSVR nonconserved highEffect-0.5 MicroRNA.org 7.384E-3 3.280E-2
2.034E-1
1.000E0
 1 107
39 hsa-miR-3605-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.453E-3 3.280E-2
2.034E-1
1.000E0
 1 108
40 hsa-miR-299-3p:PITA hsa-miR-299-3p:PITA TOP PITA 7.522E-3 3.280E-2
2.034E-1
1.000E0
 1 109
41 hsa-miR-4457:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.590E-3 3.280E-2
2.034E-1
1.000E0
 1 110
42 hsa-miR-125b-2-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.728E-3 3.280E-2
2.034E-1
1.000E0
 1 112
43 hsa-miR-6747-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.003E-3 3.280E-2
2.034E-1
1.000E0
 1 116
44 hsa-miR-216b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.072E-3 3.280E-2
2.034E-1
1.000E0
 1 117
45 hsa-miR-206:Functional MTI Functional MTI miRTarbase 8.416E-3 3.280E-2
2.034E-1
1.000E0
 1 122
46 hsa-miR-4691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.553E-3 3.280E-2
2.034E-1
1.000E0
 1 124
47 ACACTAC,MIR-142-3P:MSigDB ACACTAC,MIR-142-3P:MSigDB MSigDB 8.553E-3 3.280E-2
2.034E-1
1.000E0
 1 124
48 hsa-miR-4709-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.691E-3 3.280E-2
2.034E-1
1.000E0
 1 126
49 hsa-miR-1292:mirSVR highEffct hsa-miR-1292:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.691E-3 3.280E-2
2.034E-1
1.000E0
 1 126
50 hsa-miR-1254:PITA hsa-miR-1254:PITA TOP PITA 9.103E-3 3.280E-2
2.034E-1
1.000E0
 1 132
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 1878 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000189075 3-doxylandrostanol Stitch 4.228E-10 7.798E-7 6.328E-6 7.941E-7 3 9
2 CID000125890 26-nor-25-doxylcholestanol Stitch 8.305E-10 7.798E-7 6.328E-6 1.560E-6 3 11
3 CID000462688 AC1LA6MM Stitch 3.833E-7 2.399E-4 1.947E-3 7.198E-4 2 5
4 CID005313815 AC1NSPXR Stitch 2.107E-6 9.892E-4 8.028E-3 3.957E-3 2 11
5 2918 UP Sotalol hydrochloride [959-24-0]; Up 200; 13uM; HL60; HT HG-U133A Broad Institute CMAP Up 6.335E-6 2.379E-3 1.931E-2 1.190E-2 3 198
6 CID000019458 AC1L2E5V Stitch 1.553E-5 4.212E-3 3.419E-2 2.916E-2 2 29
7 CID000074162 diisopropylphosphate Stitch 1.664E-5 4.212E-3 3.419E-2 3.124E-2 2 30
8 CID000122038 fluorescein-5-maleimide Stitch 1.897E-5 4.212E-3 3.419E-2 3.562E-2 2 32
9 CID000115184 H2DIDS Stitch 2.019E-5 4.212E-3 3.419E-2 3.791E-2 2 33
10 CID000000767 bicarbonate Stitch 2.795E-5 5.088E-3 4.129E-2
5.248E-2
 3 325
11 CID009543517 DB08097 Stitch 2.980E-5 5.088E-3 4.129E-2
5.597E-2
 2 40
12 CID000482125 5'-CG-3 Stitch 3.613E-5 5.655E-3 4.589E-2
6.786E-2
 2 44
13 CID000002537 Camphor Stitch 5.061E-5 7.312E-3
5.934E-2
9.505E-2
 2 52
14 CID000030956 AC1L1KMJ Stitch 8.718E-5 8.747E-3
7.098E-2
1.637E-1
 3 476
15 CID000010340 sodium bicarbonate Stitch 1.029E-4 8.747E-3
7.098E-2
1.932E-1
 2 74
16 CID009543487 C4 m Stitch 1.173E-4 8.747E-3
7.098E-2
2.203E-1
 2 79
17 CID000091176 cnicin Stitch 1.592E-4 8.747E-3
7.098E-2
2.990E-1
 2 92
18 CID000001795 EIPA Stitch 1.698E-4 8.747E-3
7.098E-2
3.189E-1
 2 95
19 CID005459392 Thiophosphonoacetic Acid Stitch 1.734E-4 8.747E-3
7.098E-2
3.256E-1
 2 96
20 ctd:C523184 mocetinostat CTD 2.114E-4 8.747E-3
7.098E-2
3.970E-1
 2 106
21 CID005317455 galeopsin Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
22 CID000095922 N',N'-dibenzylbenzohydrazide Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
23 CID000076646 dimethylaminopropanol Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
24 CID000010385 leptodactyline Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
25 CID000083362 7-chloromethyl-12-methylbenz(a)anthracene Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
26 CID000096777 adenosine-5'-mononicotinate Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
27 CID006438896 DMS-1-P Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
28 CID003080767 3-methoxyphenylglyoxal Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
29 CID000364427 1,5,9-trinitrobishomopentaprismane Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
30 CID000090351 acoradiene Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
31 CID000062597 ammonium hydrogen oxalate Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
32 CID000011818 1,3-dinitronaphthalene Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
33 CID000007483 N-methyl-p-nitroaniline Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
34 CID000147389 AC1L3V2A Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
35 CID006454938 AC1O5AGC Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
36 CID000070643 4-methoxyphenylglyoxal Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
37 CID000134046 bis(2-chloroethyl)ammonium hexachlorostannate Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
38 CID000442739 droserone Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
39 CID006444151 asperketal B Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
40 CID000228282 myo-inositolhexa-acetate Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
41 CID000135171 CpP n Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
42 CID000092938 4,4'-azobis(4-cyanovaleric acid Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
43 CID003016920 Lys-Phe-Lys Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
44 ctd:C022306 4,4'-dinitro-2,2'-stilbenedisulfonic acid CTD 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
45 CID000177602 AC1L42UF Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
46 ctd:C569105 lumacaftor CTD 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
47 CID000006515 ethyltriethoxysilane Stitch 2.189E-4 8.747E-3
7.098E-2
4.111E-1
 1 1
48 CID000011502 trans-1,2-diphenylethylene Stitch 2.575E-4 9.514E-3
7.721E-2
4.837E-1
 2 117
49 CID000448294 AC1L9LT0 Stitch 2.846E-4 9.514E-3
7.721E-2
5.345E-1
 2 123
50 CID004369374 AC1N9ZZC Stitch 4.173E-4 9.514E-3
7.721E-2
7.837E-1
 2 149
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 207 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0553720 Spherocytosis DisGeNET Curated 7.614E-7 7.880E-5 4.659E-4 1.576E-4 2 5
2 C0221409 Anemia, hereditary spherocytic hemolytic DisGeNET Curated 7.614E-7 7.880E-5 4.659E-4 1.576E-4 2 5
3 C0272051 Xerocytosis DisGeNET Curated 2.740E-6 1.890E-4 1.118E-3 5.671E-4 2 9
4 C0311468 Increased bilirubin level (finding) DisGeNET Curated 1.163E-5 5.978E-4 3.534E-3 2.407E-3 2 18
5 C0206160 Reticulocytosis DisGeNET Curated 1.444E-5 5.978E-4 3.534E-3 2.989E-3 2 20
6 C0037889 Hereditary spherocytosis DisGeNET Curated 3.529E-5 1.218E-3 7.198E-3 7.305E-3 2 31
7 cv:C1862191 BLOOD GROUP--WALDNER TYPE Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
8 OMIN:611590 RENAL TUBULAR ACIDOSIS, DISTAL, WITH HEMOLYTIC ANEMIA OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
9 cv:C2675212 Spherocytosis type 4 Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
10 cv:C2674218 Spherocytosis type 1 Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
11 OMIN:612653 SPHEROCYTOSIS, TYPE 4; SPH4 OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
12 OMIN:601551 BLOOD GROUP--FROESE OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
13 cv:C1862190 BLOOD GROUP--WRIGHT ANTIGEN Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
14 C1969038 RENAL TUBULAR ACIDOSIS, DISTAL, WITH HEMOLYTIC ANEMIA (disorder) DisGeNET Curated 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
15 cv:C0259810 Renal tubular acidosis, distal, autosomal dominant Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
16 OMIN:112050 BLOOD GROUP--WRIGHT ANTIGEN; WR OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
17 cv:C1832168 BLOOD GROUP--FROESE Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
18 cv:C1969038 Renal tubular acidosis, distal, with hemolytic anemia Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
19 C2675212 Spherocytosis, Type 4 DisGeNET Curated 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
20 cv:C2675527 Myopathy, congenital, compton-north Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
21 cv:CN181196 Mental retardation, autosomal recessive 37 Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
22 OMIN:112010 BLOOD GROUP--WALDNER TYPE; WD OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
23 C3809672 MENTAL RETARDATION, AUTOSOMAL RECESSIVE 37 DisGeNET Curated 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
24 OMIN:110500 BLOOD GROUP--DIEGO SYSTEM; DI OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
25 OMIN:601550 BLOOD GROUP--SWANN SYSTEM; SW OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
26 C1844680 DEAFNESS-HYPOGONADISM SYNDROME DisGeNET BeFree 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
27 OMIN:612540 MYOPATHY, CONGENITAL, COMPTON-NORTH OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
28 cv:C0011848 BLOOD GROUP--DIEGO SYSTEM Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
29 cv:C1832169 BLOOD GROUP--SWANN SYSTEM Clinical Variations 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
30 C2675527 Myopathy, Congenital, Compton-North DisGeNET Curated 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
31 OMIN:179800 RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL DOMINANT OMIM 3.085E-4 2.060E-3 1.218E-2
6.387E-2
 1 1
32 C0002878 Anemia, Hemolytic DisGeNET Curated 4.838E-4 3.130E-3 1.850E-2
1.002E-1
 2 114
33 OMIN:182900 SPHEROCYTOSIS, TYPE 1; SPH1 OMIM 6.170E-4 3.649E-3 2.158E-2
1.277E-1
 1 2
34 C0409896 Familial chondrocalcinosis DisGeNET Curated 6.170E-4 3.649E-3 2.158E-2
1.277E-1
 1 2
35 OMIN:602722 RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE; RTADR OMIM 6.170E-4 3.649E-3 2.158E-2
1.277E-1
 1 2
36 C0022346 Icterus DisGeNET Curated 6.480E-4 3.726E-3 2.203E-2
1.341E-1
 2 132
37 C0010598 Cyclothymic Disorder DisGeNET BeFree 9.254E-4 5.177E-3 3.061E-2
1.916E-1
 1 3
38 C0005806 Blood Group Incompatibility DisGeNET BeFree 1.234E-3 6.081E-3 3.595E-2
2.554E-1
 1 4
39 C0856830 Calcium pyrophosphate arthropathy DisGeNET Curated 1.234E-3 6.081E-3 3.595E-2
2.554E-1
 1 4
40 C1849478 Increased red cell osmotic fragility DisGeNET Curated 1.234E-3 6.081E-3 3.595E-2
2.554E-1
 1 4
41 C0242217 Calcium Pyrophosphate Dihydrate Deposition DisGeNET BeFree 1.234E-3 6.081E-3 3.595E-2
2.554E-1
 1 4
42 20081125:Ferreira Bipolar disorder GWAS 1.234E-3 6.081E-3 3.595E-2
2.554E-1
 1 4
43 C0038002 Splenomegaly DisGeNET Curated 1.322E-3 6.365E-3 3.763E-2
2.737E-1
 2 189
44 C0265292 Schwartz-Lelek syndrome DisGeNET Curated 1.542E-3 6.791E-3 4.015E-2
3.192E-1
 1 5
45 C1849025 Oval face DisGeNET Curated 1.542E-3 6.791E-3 4.015E-2
3.192E-1
 1 5
46 C1864498 RENAL TUBULAR ACIDOSIS, DISTAL, AUTOSOMAL RECESSIVE DisGeNET Curated 1.542E-3 6.791E-3 4.015E-2
3.192E-1
 1 5
47 C0740749 Chronic metabolic acidosis DisGeNET Curated 1.542E-3 6.791E-3 4.015E-2
3.192E-1
 1 5
48 C1861455 STOMATOCYTOSIS I DisGeNET Curated 1.850E-3 7.509E-3 4.440E-2
3.830E-1
 1 6
49 C1862323 OVALOCYTOSIS, SOUTHEAST ASIAN DisGeNET Curated 1.850E-3 7.509E-3 4.440E-2
3.830E-1
 1 6
50 C3541994 Drug Hypersensitivity Syndrome DisGeNET BeFree 1.850E-3 7.509E-3 4.440E-2
3.830E-1
 1 6
Show 45 more annotations