Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc357_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 53 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0017075 syntaxin-1 binding 1.051E-8 5.572E-7 2.539E-6 5.572E-7 3 20
2 GO:0019905 syntaxin binding 1.394E-6 3.694E-5 1.683E-4 7.387E-5 3 98
3 GO:0000149 SNARE binding 3.583E-6 6.329E-5 2.884E-4 1.899E-4 3 134
4 GO:0030549 acetylcholine receptor activator activity 2.679E-4 3.550E-3 1.618E-2 1.420E-2 1 1
5 GO:0000403 Y-form DNA binding 1.071E-3 7.886E-3 3.594E-2
5.678E-2
 1 4
6 GO:0005176 ErbB-2 class receptor binding 1.071E-3 7.886E-3 3.594E-2
5.678E-2
 1 4
7 GO:0043125 ErbB-3 class receptor binding 1.339E-3 7.886E-3 3.594E-2
7.097E-2
 1 5
8 GO:0030548 acetylcholine receptor regulator activity 1.339E-3 7.886E-3 3.594E-2
7.097E-2
 1 5
9 GO:0099602 neurotransmitter receptor regulator activity 1.339E-3 7.886E-3 3.594E-2
7.097E-2
 1 5
10 GO:0050321 tau-protein kinase activity 3.211E-3 1.702E-2
7.756E-2
1.702E-1
 1 12
11 GO:0043142 single-stranded DNA-dependent ATPase activity 3.746E-3 1.805E-2
8.225E-2
1.985E-1
 1 14
12 GO:0000217 DNA secondary structure binding 6.681E-3 2.951E-2
1.345E-1
3.541E-1
 1 25
13 GO:0046875 ephrin receptor binding 7.747E-3 3.095E-2
1.410E-1
4.106E-1
 1 29
14 GO:0030546 receptor activator activity 9.344E-3 3.095E-2
1.410E-1
4.952E-1
 1 35
15 GO:0097472 cyclin-dependent protein kinase activity 9.344E-3 3.095E-2
1.410E-1
4.952E-1
 1 35
16 GO:0004693 cyclin-dependent protein serine/threonine kinase activity 9.344E-3 3.095E-2
1.410E-1
4.952E-1
 1 35
17 GO:0031593 polyubiquitin modification-dependent protein binding 1.227E-2 3.824E-2
1.743E-1
6.501E-1
 1 46
18 GO:0030545 receptor regulator activity 1.359E-2 4.002E-2
1.824E-1
7.204E-1
 1 51
19 GO:0003684 damaged DNA binding 1.730E-2 4.825E-2
2.199E-1
9.167E-1
 1 65
Show 14 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 317 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0017157 regulation of exocytosis 7.069E-8 2.241E-5 1.420E-4 2.241E-5 4 205
2 GO:0045921 positive regulation of exocytosis 1.197E-6 1.174E-4 7.440E-4 3.794E-4 3 93
3 GO:0017158 regulation of calcium ion-dependent exocytosis 1.277E-6 1.174E-4 7.440E-4 4.047E-4 3 95
4 GO:0006887 exocytosis 1.481E-6 1.174E-4 7.440E-4 4.696E-4 4 438
5 GO:0017156 calcium ion regulated exocytosis 3.524E-6 2.234E-4 1.416E-3 1.117E-3 3 133
6 GO:1903305 regulation of regulated secretory pathway 4.477E-6 2.365E-4 1.499E-3 1.419E-3 3 144
7 GO:0045956 positive regulation of calcium ion-dependent exocytosis 2.174E-5 9.845E-4 6.239E-3 6.891E-3 2 28
8 GO:1902803 regulation of synaptic vesicle transport 3.620E-5 1.434E-3 9.091E-3 1.148E-2 2 36
9 GO:0006904 vesicle docking involved in exocytosis 4.480E-5 1.482E-3 9.391E-3 1.420E-2 2 40
10 GO:0045055 regulated exocytosis 4.674E-5 1.482E-3 9.391E-3 1.482E-2 3 315
11 GO:0007596 blood coagulation 7.134E-5 1.812E-3 1.148E-2 2.262E-2 3 363
12 GO:0007599 hemostasis 7.431E-5 1.812E-3 1.148E-2 2.356E-2 3 368
13 GO:0050817 coagulation 7.431E-5 1.812E-3 1.148E-2 2.356E-2 3 368
14 GO:1903307 positive regulation of regulated secretory pathway 8.830E-5 1.999E-3 1.267E-2 2.799E-2 2 56
15 GO:0070527 platelet aggregation 9.807E-5 2.010E-3 1.274E-2 3.109E-2 2 59
16 GO:0048278 vesicle docking 1.014E-4 2.010E-3 1.274E-2 3.216E-2 2 60
17 GO:1903532 positive regulation of secretion by cell 1.078E-4 2.010E-3 1.274E-2 3.417E-2 3 417
18 GO:0051047 positive regulation of secretion 1.352E-4 2.381E-3 1.509E-2 4.285E-2 3 450
19 GO:0022406 membrane docking 1.504E-4 2.509E-3 1.590E-2 4.768E-2 2 73
20 GO:0007409 axonogenesis 1.587E-4 2.515E-3 1.594E-2
5.031E-2
 3 475
21 GO:0023061 signal release 1.826E-4 2.756E-3 1.747E-2
5.789E-2
 3 498
22 GO:0016079 synaptic vesicle exocytosis 2.288E-4 3.297E-3 2.089E-2
7.253E-2
 2 90
23 GO:0099504 synaptic vesicle cycle 4.134E-4 5.697E-3 3.611E-2
1.310E-1
 2 121
24 GO:0048489 synaptic vesicle transport 4.991E-4 6.329E-3 4.011E-2
1.582E-1
 2 133
25 GO:0097480 establishment of synaptic vesicle localization 4.991E-4 6.329E-3 4.011E-2
1.582E-1
 2 133
26 GO:0097479 synaptic vesicle localization 5.608E-4 6.837E-3 4.333E-2
1.778E-1
 2 141
27 GO:0007270 neuron-neuron synaptic transmission 6.684E-4 7.847E-3 4.973E-2
2.119E-1
 2 154
28 GO:0099643 signal release from synapse 7.483E-4 7.977E-3
5.056E-2
2.372E-1
 2 163
29 GO:0007269 neurotransmitter secretion 7.483E-4 7.977E-3
5.056E-2
2.372E-1
 2 163
30 GO:0030168 platelet activation 7.947E-4 7.977E-3
5.056E-2
2.519E-1
 2 168
31 GO:0048167 regulation of synaptic plasticity 8.041E-4 7.977E-3
5.056E-2
2.549E-1
 2 169
32 GO:0031630 regulation of synaptic vesicle fusion to presynaptic active zone membrane 8.053E-4 7.977E-3
5.056E-2
2.553E-1
 1 3
33 GO:0099531 presynaptic process involved in chemical synaptic transmission 8.424E-4 8.092E-3
5.128E-2
2.670E-1
 2 173
34 GO:0007412 axon target recognition 1.074E-3 9.724E-3
6.163E-2
3.403E-1
 1 4
35 GO:0031914 negative regulation of synaptic plasticity 1.074E-3 9.724E-3
6.163E-2
3.403E-1
 1 4
36 GO:1901215 negative regulation of neuron death 1.168E-3 1.029E-2
6.521E-2
3.704E-1
 2 204
37 GO:0006836 neurotransmitter transport 1.261E-3 1.072E-2
6.792E-2
3.997E-1
 2 212
38 GO:0001505 regulation of neurotransmitter levels 1.285E-3 1.072E-2
6.792E-2
4.072E-1
 2 214
39 GO:0043523 regulation of neuron apoptotic process 1.559E-3 1.268E-2
8.033E-2
4.943E-1
 2 236
40 GO:0051650 establishment of vesicle localization 1.775E-3 1.407E-2
8.917E-2
5.628E-1
 2 252
41 GO:0051402 neuron apoptotic process 1.903E-3 1.448E-2
9.174E-2
6.032E-1
 2 261
42 GO:0051648 vesicle localization 1.990E-3 1.448E-2
9.174E-2
6.309E-1
 2 267
43 GO:0050803 regulation of synapse structure or activity 2.065E-3 1.448E-2
9.174E-2
6.545E-1
 2 272
44 GO:0032229 negative regulation of synaptic transmission, GABAergic 2.146E-3 1.448E-2
9.174E-2
6.804E-1
 1 8
45 GO:0046826 negative regulation of protein export from nucleus 2.146E-3 1.448E-2
9.174E-2
6.804E-1
 1 8
46 GO:0022615 protein to membrane docking 2.146E-3 1.448E-2
9.174E-2
6.804E-1
 1 8
47 GO:1903421 regulation of synaptic vesicle recycling 2.146E-3 1.448E-2
9.174E-2
6.804E-1
 1 8
48 GO:0035542 regulation of SNARE complex assembly 2.414E-3 1.562E-2
9.899E-2
7.653E-1
 1 9
49 GO:0010807 regulation of synaptic vesicle priming 2.414E-3 1.562E-2
9.899E-2
7.653E-1
 1 9
50 GO:1901214 regulation of neuron death 2.621E-3 1.662E-2
1.053E-1
8.309E-1
 2 307
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 47 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0098793 presynapse 5.526E-5 2.089E-3 9.271E-3 2.597E-3 3 341
2 GO:0030141 secretory granule 8.889E-5 2.089E-3 9.271E-3 4.178E-3 3 400
3 GO:0031091 platelet alpha granule 1.516E-4 2.375E-3 1.054E-2 7.125E-3 2 75
4 GO:0097505 Rad6-Rad18 complex 2.623E-4 3.082E-3 1.368E-2 1.233E-2 1 1
5 GO:0016533 protein kinase 5 complex 7.868E-4 7.396E-3 3.282E-2 3.698E-2 1 3
6 GO:0070820 tertiary granule 1.573E-3 1.232E-2
5.469E-2
7.393E-2
 1 6
7 GO:0042405 nuclear inclusion body 3.144E-3 2.111E-2
9.369E-2
1.478E-1
 1 12
8 GO:0042581 specific granule 3.667E-3 2.155E-2
9.562E-2
1.724E-1
 1 14
9 GO:0001741 XY body 4.452E-3 2.325E-2
1.032E-1
2.092E-1
 1 17
10 GO:0005892 acetylcholine-gated channel complex 6.019E-3 2.829E-2
1.256E-1
2.829E-1
 1 23
11 GO:0000803 sex chromosome 8.367E-3 3.379E-2
1.500E-1
3.932E-1
 1 32
12 GO:0035861 site of double-strand break 8.627E-3 3.379E-2
1.500E-1
4.055E-1
 1 33
Show 7 more annotations

4: Human Phenotype [Display Chart] 3 input genes in category / 455 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 5 input genes in category / 117 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 5 input genes in category / 46 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR001619 Sec1-like InterPro 1.595E-6 1.834E-5 8.099E-5 7.335E-5 2 8
2 PF00995 Sec1 Pfam 1.595E-6 1.834E-5 8.099E-5 7.335E-5 2 8
3 IPR027482 Sec-1-like dom2 InterPro 1.595E-6 1.834E-5 8.099E-5 7.335E-5 2 8
4 3.40.50.1910 - Gene3D 1.595E-6 1.834E-5 8.099E-5 7.335E-5 2 8
5 IPR013905 Lgl C dom InterPro 5.337E-4 4.092E-3 1.807E-2 2.455E-2 1 2
6 PF08596 Lgl C Pfam 5.337E-4 4.092E-3 1.807E-2 2.455E-2 1 2
7 IPR013577 LLGL2 InterPro 1.067E-3 5.454E-3 2.409E-2 4.909E-2 1 4
8 PF08366 LLGL Pfam 1.067E-3 5.454E-3 2.409E-2 4.909E-2 1 4
9 IPR000664 Lethal2 giant InterPro 1.067E-3 5.454E-3 2.409E-2 4.909E-2 1 4
10 IPR006642 Znf Rad18 put InterPro 1.334E-3 5.578E-3 2.464E-2
6.136E-2
 1 5
11 SM00734 ZnF Rad18 SMART 1.334E-3 5.578E-3 2.464E-2
6.136E-2
 1 5
12 IPR011048 Haem d1 InterPro 1.600E-3 6.135E-3 2.710E-2
7.362E-2
 1 6
13 PS50892 V SNARE PROSITE 3.199E-3 1.132E-2 4.999E-2
1.471E-1
 1 12
14 IPR001388 Synaptobrevin InterPro 3.465E-3 1.139E-2
5.028E-2
1.594E-1
 1 13
15 1.10.720.30 - Gene3D 5.593E-3 1.611E-2
7.116E-2
2.573E-1
 1 21
16 PF02037 SAP Pfam 5.858E-3 1.611E-2
7.116E-2
2.695E-1
 1 22
17 SM00513 SAP SMART 6.124E-3 1.611E-2
7.116E-2
2.817E-1
 1 23
18 PS50800 SAP PROSITE 6.655E-3 1.611E-2
7.116E-2
3.061E-1
 1 25
19 IPR003034 SAP dom InterPro 6.655E-3 1.611E-2
7.116E-2
3.061E-1
 1 25
Show 14 more annotations

7: Pathway [Display Chart] 4 input genes in category / 49 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269366 Disinhibition of SNARE formation BioSystems: REACTOME 1.606E-3 1.945E-2
8.712E-2
7.868E-2
 1 5
2 138028 Effects of Botulinum toxin BioSystems: Pathway Interaction Database 2.889E-3 1.945E-2
8.712E-2
1.416E-1
 1 9
3 M12718 Deregulation of CDK5 in Alzheimers Disease MSigDB C2 BIOCARTA (v6.0) 3.530E-3 1.945E-2
8.712E-2
1.730E-1
 1 11
4 M89 Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway MSigDB C2 BIOCARTA (v6.0) 3.530E-3 1.945E-2
8.712E-2
1.730E-1
 1 11
5 1270310 CRMPs in Sema3A signaling BioSystems: REACTOME 5.131E-3 1.945E-2
8.712E-2
2.514E-1
 1 16
6 M16626 Regulation of ck1/cdk5 by type 1 glutamate receptors MSigDB C2 BIOCARTA (v6.0) 5.451E-3 1.945E-2
8.712E-2
2.671E-1
 1 17
7 1268773 Acetylcholine Neurotransmitter Release Cycle BioSystems: REACTOME 5.451E-3 1.945E-2
8.712E-2
2.671E-1
 1 17
8 1268769 Norepinephrine Neurotransmitter Release Cycle BioSystems: REACTOME 5.771E-3 1.945E-2
8.712E-2
2.828E-1
 1 18
9 PW:0000674 insulin secretion pathway Pathway Ontology 5.771E-3 1.945E-2
8.712E-2
2.828E-1
 1 18
10 1268770 Serotonin Neurotransmitter Release Cycle BioSystems: REACTOME 5.771E-3 1.945E-2
8.712E-2
2.828E-1
 1 18
11 1268774 GABA synthesis, release, reuptake and degradation BioSystems: REACTOME 6.091E-3 1.945E-2
8.712E-2
2.985E-1
 1 19
12 PW:0000639 insulin responsive facilitative sugar transporter mediated glucose transport pathway Pathway Ontology 6.091E-3 1.945E-2
8.712E-2
2.985E-1
 1 19
13 P00007 Axon guidance mediated by semaphorins PantherDB 6.091E-3 1.945E-2
8.712E-2
2.985E-1
 1 19
14 P05734 Synaptic vesicle trafficking PantherDB 7.370E-3 1.945E-2
8.712E-2
3.611E-1
 1 23
15 1268772 Dopamine Neurotransmitter Release Cycle BioSystems: REACTOME 7.370E-3 1.945E-2
8.712E-2
3.611E-1
 1 23
16 1457788 Neurodegenerative Diseases BioSystems: REACTOME 7.370E-3 1.945E-2
8.712E-2
3.611E-1
 1 23
17 1457789 Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models BioSystems: REACTOME 7.370E-3 1.945E-2
8.712E-2
3.611E-1
 1 23
18 M8601 Rac 1 cell motility signaling pathway MSigDB C2 BIOCARTA (v6.0) 7.370E-3 1.945E-2
8.712E-2
3.611E-1
 1 23
19 1268771 Glutamate Neurotransmitter Release Cycle BioSystems: REACTOME 7.689E-3 1.945E-2
8.712E-2
3.768E-1
 1 24
20 1269591 DARPP-32 events BioSystems: REACTOME 8.648E-3 1.945E-2
8.712E-2
4.237E-1
 1 27
21 138044 Trk receptor signaling mediated by the MAPK pathway BioSystems: Pathway Interaction Database 9.286E-3 1.945E-2
8.712E-2
4.550E-1
 1 29
22 137980 Reelin signaling pathway BioSystems: Pathway Interaction Database 9.286E-3 1.945E-2
8.712E-2
4.550E-1
 1 29
23 1270368 Recognition of DNA damage by PCNA-containing replication complex BioSystems: REACTOME 9.605E-3 1.945E-2
8.712E-2
4.706E-1
 1 30
24 138041 EPHA forward signaling BioSystems: Pathway Interaction Database 9.924E-3 1.945E-2
8.712E-2
4.863E-1
 1 31
25 137984 Lissencephaly gene (LIS1) in neuronal migration and development BioSystems: Pathway Interaction Database 9.924E-3 1.945E-2
8.712E-2
4.863E-1
 1 31
26 M13494 Bioactive Peptide Induced Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 1.375E-2 2.590E-2
1.160E-1
6.735E-1
 1 43
27 546258 Cocaine addiction BioSystems: KEGG 1.565E-2 2.752E-2
1.233E-1
7.670E-1
 1 49
28 1270367 DNA Damage Bypass BioSystems: REACTOME 1.597E-2 2.752E-2
1.233E-1
7.825E-1
 1 50
29 1268768 Neurotransmitter Release Cycle BioSystems: REACTOME 1.629E-2 2.752E-2
1.233E-1
7.981E-1
 1 51
30 1427850 Interactions of neurexins and neuroligins at synapses BioSystems: REACTOME 1.882E-2 3.075E-2
1.377E-1
9.224E-1
 1 59
31 1269896 Translocation of GLUT4 to the plasma membrane BioSystems: REACTOME 1.977E-2 3.076E-2
1.378E-1
9.689E-1
 1 62
32 373900 Synaptic vesicle cycle BioSystems: KEGG 2.009E-2 3.076E-2
1.378E-1
9.844E-1
 1 63
33 1270304 Semaphorin interactions BioSystems: REACTOME 2.167E-2 3.218E-2
1.441E-1
1.000E0
 1 68
34 1427849 Protein-protein interactions at synapses BioSystems: REACTOME 2.325E-2 3.351E-2
1.501E-1
1.000E0
 1 73
35 1270102 Regulation of insulin secretion BioSystems: REACTOME 2.546E-2 3.551E-2
1.591E-1
1.000E0
 1 80
36 138014 Glucocorticoid receptor regulatory network BioSystems: Pathway Interaction Database 2.609E-2 3.551E-2
1.591E-1
1.000E0
 1 82
37 1269584 Opioid Signalling BioSystems: REACTOME 2.703E-2 3.580E-2
1.604E-1
1.000E0
 1 85
38 1383080 Regulation of TP53 Activity through Phosphorylation BioSystems: REACTOME 2.955E-2 3.810E-2
1.707E-1
1.000E0
 1 93
39 1270101 Integration of energy metabolism BioSystems: REACTOME 3.519E-2 4.422E-2
1.981E-1
1.000E0
 1 111
Show 34 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 933 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 25190515 Doc2b serves as a scaffolding platform for concurrent binding of multiple Munc18 isoforms in pancreatic islet β-cells. Pubmed 4.113E-8 8.527E-6 6.324E-5 3.838E-5 2 3
2 16413130 Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease. Pubmed 4.113E-8 8.527E-6 6.324E-5 3.838E-5 2 3
3 8824310 A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants. Pubmed 4.113E-8 8.527E-6 6.324E-5 3.838E-5 2 3
4 7890715 Molecular identification of two novel Munc-18 isoforms expressed in non-neuronal tissues. Pubmed 4.113E-8 8.527E-6 6.324E-5 3.838E-5 2 3
5 20053958 Exocytosis mechanisms underlying insulin release and glucose uptake: conserved roles for Munc18c and syntaxin 4. Pubmed 8.226E-8 8.527E-6 6.324E-5 7.675E-5 2 4
6 29599294 Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells. Pubmed 8.226E-8 8.527E-6 6.324E-5 7.675E-5 2 4
7 15123626 Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis. Pubmed 8.226E-8 8.527E-6 6.324E-5 7.675E-5 2 4
8 15690082 Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization. Pubmed 8.226E-8 8.527E-6 6.324E-5 7.675E-5 2 4
9 28325894 SUMOylation and calcium control syntaxin-1A and secretagogin sequestration by tomosyn to regulate insulin exocytosis in human Ã? cells. Pubmed 8.226E-8 8.527E-6 6.324E-5 7.675E-5 2 4
10 15659226 Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain. Pubmed 1.371E-7 1.279E-5 9.486E-5 1.279E-4 2 5
11 12297296 Cellular munc18c levels can modulate glucose transport rate and GLUT4 translocation in 3T3L1 cells. Pubmed 2.056E-7 1.744E-5 1.293E-4 1.918E-4 2 6
12 12773094 A role for Sec1/Munc18 proteins in platelet exocytosis. Pubmed 2.879E-7 2.238E-5 1.660E-4 2.686E-4 2 7
13 12963086 Co-purification and localization of Munc18-1 (p67) and Cdk5 with neuronal cytoskeletal proteins. Pubmed 3.838E-7 2.754E-5 2.043E-4 3.581E-4 2 8
14 10194441 Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion. Pubmed 4.934E-7 3.288E-5 2.439E-4 4.604E-4 2 9
15 12832401 Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation. Pubmed 7.538E-7 4.688E-5 3.477E-4 7.033E-4 2 11
16 15217342 The synaptic vesicle cycle. Pubmed 6.366E-6 3.712E-4 2.753E-3 5.939E-3 2 31
17 19144319 The phagosomal proteome in interferon-gamma-activated macrophages. Pubmed 8.144E-6 4.470E-4 3.315E-3 7.598E-3 2 35
18 15572359 Proteomic analysis of in vivo phosphorylated synaptic proteins. Pubmed 1.813E-5 4.985E-4 3.697E-3 1.692E-2 2 52
19 19514265 [Role of Cdk5 in axon guidance and synapse development]. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
20 25418441 A novel de novo STXBP1 mutation is associated with mitochondrial complex I deficiency and late-onset juvenile-onset parkinsonism. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
21 17158148 Human RAD18 is involved in S phase-specific single-strand break repair without PCNA monoubiquitination. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
22 17914568 Single nucleotide polymorphism in the RAD18 gene and risk of colorectal cancer in the Japanese population. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
23 12527361 Glucosamine-induced insulin resistance is coupled to O-linked glycosylation of Munc18c. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
24 19068231 Rad18 is required for long-term maintenance of spermatogenesis in mouse testes. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
25 21044075 Regulation and role of cyclin-dependent kinase activity in neuronal survival and death. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
26 22211739 Association of genomic deletions in the STXBP1 gene with Ohtahara syndrome. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
27 15489225 Fluorescence resonance energy transfer reports properties of syntaxin1a interaction with Munc18-1 in vivo. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
28 26018459 Cyclin-dependent kinase 5 regulates the proliferation, motility and invasiveness of lung cancer cells through its effects on cytoskeletal remodeling. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
29 19493487 [Effect of hydroquinone on expression of ubiquitin-ligating enzyme Rad18 in human L-02 hepatic cells]. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
30 20681955 Munc18-1 as a key regulator of neurosecretion. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
31 8090222 A brain-specific activator of cyclin-dependent kinase 5. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
32 11739578 Neocortical cell migration: GABAergic neurons and cells in layers I and VI move in a cyclin-dependent kinase 5-independent manner. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
33 19017804 Striatal dysregulation of Cdk5 alters locomotor responses to cocaine, motor learning, and dendritic morphology. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
34 8891282 Intracellular localization of cyclin-dependent kinase 5 (CDK5) in mouse neuron: CDK5 is located in both nucleus and cytoplasm. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
35 24851929 All-trans retinoic acid induces DU145 cell cycle arrest through Cdk5 activation. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
36 25346443 Cyclin-dependent kinase 5 regulates degranulation in human eosinophils. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
37 25609066 Cyclin-dependent kinase 5 decreases in gastric cancer and its nuclear accumulation suppresses gastric tumorigenesis. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
38 14769920 Cyclin-dependent kinase 5 regulates dopaminergic and glutamatergic transmission in the striatum. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
39 17442248 Interdependence of PKC-dependent and PKC-independent pathways for presynaptic plasticity. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
40 15935062 Implication of cyclin-dependent kinase 5 in the development of psychological dependence on and behavioral sensitization to morphine. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
41 21600237 Cdk5: mediator of neuronal development, death and the response to DNA damage. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
42 28589675 Cdk5 activity is required for Purkinje cell dendritic growth in cell-autonomous and non-cell-autonomous manners. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
43 14712065 Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
44 11545717 Munc18-1 promotes large dense-core vesicle docking. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
45 24590174 Munc18-1 redistributes in nerve terminals in an activity- and PKC-dependent manner. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
46 24518219 RAD18 mediates resistance to ionizing radiation in human glioma cells. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
47 21364700 Intellectual disability without epilepsy associated with STXBP1 disruption. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
48 24121667 CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
49 24391775 Milligram quantities of homogeneous recombinant full-length mouse Munc18c from Escherichia coli cultures. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
50 8543173 Promoter region of the mouse cyclin-dependent kinase 5-encoding gene. Pubmed 1.309E-4 4.985E-4 3.697E-3
1.221E-1
 1 1
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 411 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:STX1A STX1A interactions 7.557E-7 1.680E-4 1.108E-3 3.106E-4 3 76
2 int:STX4 STX4 interactions 8.176E-7 1.680E-4 1.108E-3 3.361E-4 3 78
3 int:GPRC5B GPRC5B interactions 1.089E-5 1.099E-3 7.252E-3 4.477E-3 2 19
4 int:STX19 STX19 interactions 1.337E-5 1.099E-3 7.252E-3 5.497E-3 2 21
5 int:STX2 STX2 interactions 1.337E-5 1.099E-3 7.252E-3 5.497E-3 2 21
6 int:NEFH NEFH interactions 3.155E-5 2.161E-3 1.426E-2 1.297E-2 2 32
7 int:CDK5R1 CDK5R1 interactions 7.162E-5 4.205E-3 2.774E-2 2.943E-2 2 48
8 int:STX3 STX3 interactions 1.486E-4 6.388E-3 4.214E-2
6.107E-2
 2 69
9 int:SNAP23 SNAP23 interactions 1.618E-4 6.388E-3 4.214E-2
6.652E-2
 2 72
10 int:STXBP1 STXBP1 interactions 1.664E-4 6.388E-3 4.214E-2
6.838E-2
 2 73
11 int:DIS3 DIS3 interactions 1.710E-4 6.388E-3 4.214E-2
7.027E-2
 2 74
12 int:STX11 STX11 interactions 3.577E-4 1.152E-2
7.599E-2
1.470E-1
 2 107
13 int:ACTR3 ACTR3 interactions 3.644E-4 1.152E-2
7.599E-2
1.498E-1
 2 108
14 int:MAPT MAPT interactions 5.194E-4 1.451E-2
9.571E-2
2.135E-1
 2 129
15 int:C1orf61 C1orf61 interactions 5.648E-4 1.451E-2
9.571E-2
2.321E-1
 1 2
16 int:DCLK3 DCLK3 interactions 5.648E-4 1.451E-2
9.571E-2
2.321E-1
 1 2
17 int:CDK5 CDK5 interactions 6.289E-4 1.520E-2
1.003E-1
2.585E-1
 2 142
18 int:ACTR2 ACTR2 interactions 7.013E-4 1.601E-2
1.056E-1
2.883E-1
 2 150
19 int:ECT2 ECT2 interactions 7.679E-4 1.661E-2
1.096E-1
3.156E-1
 2 157
20 int:ANPEP ANPEP interactions 8.471E-4 1.741E-2
1.148E-1
3.482E-1
 1 3
21 int:ACTN1 ACTN1 interactions 9.206E-4 1.802E-2
1.189E-1
3.784E-1
 2 172
22 int:SPTBN1 SPTBN1 interactions 1.019E-3 1.903E-2
1.256E-1
4.187E-1
 2 181
23 int:AGAP2 AGAP2 interactions 1.157E-3 2.068E-2
1.364E-1
4.756E-1
 2 193
24 int:UBE2A UBE2A interactions 1.304E-3 2.231E-2
1.472E-1
5.360E-1
 2 205
25 int:ZNF501 ZNF501 interactions 1.412E-3 2.231E-2
1.472E-1
5.801E-1
 1 5
26 int:CDK5R2 CDK5R2 interactions 1.412E-3 2.231E-2
1.472E-1
5.801E-1
 1 5
27 int:DOC2B DOC2B interactions 1.694E-3 2.381E-2
1.571E-1
6.961E-1
 1 6
28 int:CNPPD1 CNPPD1 interactions 1.694E-3 2.381E-2
1.571E-1
6.961E-1
 1 6
29 int:CCT6A CCT6A interactions 1.709E-3 2.381E-2
1.571E-1
7.024E-1
 2 235
30 int:TCP1 TCP1 interactions 1.738E-3 2.381E-2
1.571E-1
7.143E-1
 2 237
31 int:TM4SF18 TM4SF18 interactions 1.976E-3 2.538E-2
1.674E-1
8.120E-1
 1 7
32 int:CCNI2 CCNI2 interactions 1.976E-3 2.538E-2
1.674E-1
8.120E-1
 1 7
33 int:PRKCA PRKCA interactions 2.450E-3 2.821E-2
1.861E-1
1.000E0
 2 282
34 int:TMEM94 TMEM94 interactions 2.540E-3 2.821E-2
1.861E-1
1.000E0
 1 9
35 int:CABLES2 CABLES2 interactions 2.540E-3 2.821E-2
1.861E-1
1.000E0
 1 9
36 int:CCNI CCNI interactions 2.540E-3 2.821E-2
1.861E-1
1.000E0
 1 9
37 int:ATPAF1 ATPAF1 interactions 2.540E-3 2.821E-2
1.861E-1
1.000E0
 1 9
38 int:SLF2 SLF2 interactions 2.822E-3 3.052E-2
2.013E-1
1.000E0
 1 10
39 int:SH3BGRL3 SH3BGRL3 interactions 3.103E-3 3.092E-2
2.040E-1
1.000E0
 1 11
40 int:SQSTM1 SQSTM1 interactions 3.103E-3 3.092E-2
2.040E-1
1.000E0
 2 318
41 int:PCNA PCNA interactions 3.142E-3 3.092E-2
2.040E-1
1.000E0
 2 320
42 int:PPP1R1B PPP1R1B interactions 3.385E-3 3.092E-2
2.040E-1
1.000E0
 1 12
43 int:SLF1 SLF1 interactions 3.385E-3 3.092E-2
2.040E-1
1.000E0
 1 12
44 int:SNTG1 SNTG1 interactions 3.385E-3 3.092E-2
2.040E-1
1.000E0
 1 12
45 int:DOC2A DOC2A interactions 3.385E-3 3.092E-2
2.040E-1
1.000E0
 1 12
46 int:STXBP5 STXBP5 interactions 3.667E-3 3.121E-2
2.059E-1
1.000E0
 1 13
47 int:PLPPR1 PLPPR1 interactions 3.667E-3 3.121E-2
2.059E-1
1.000E0
 1 13
48 int:GPR141 GPR141 interactions 3.667E-3 3.121E-2
2.059E-1
1.000E0
 1 13
49 int:RHNO1 RHNO1 interactions 3.948E-3 3.121E-2
2.059E-1
1.000E0
 1 14
50 int:CABLES1 CABLES1 interactions 3.948E-3 3.121E-2
2.059E-1
1.000E0
 1 14
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 3p25-p24 3p25-p24 5.769E-4 2.885E-3 6.586E-3 2.885E-3 1 4
2 6q24.3 6q24.3 1.586E-3 3.965E-3 9.053E-3 7.929E-3 1 11
3 9q34.1 9q34.1 2.738E-3 4.563E-3 1.042E-2 1.369E-2 1 19
4 7q36 7q36 3.889E-3 4.861E-3 1.110E-2 1.945E-2 1 27
5 1p13.3 1p13.3 1.006E-2 1.006E-2 2.297E-2
5.029E-2
 1 70

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 25 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 3 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 496 Cyclin dependent kinases genenames.org 4.281E-3 1.284E-2 2.355E-2 1.284E-2 1 26
2 362 Ring finger proteins|WD repeat domain containing genenames.org 4.258E-2 4.467E-2
8.189E-2
1.278E-1
 1 262
3 58 Ring finger proteins|Tripartite motif containing genenames.org 4.467E-2 4.467E-2
8.189E-2
1.340E-1
 1 275

13: Coexpression [Display Chart] 5 input genes in category / 476 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M3779 Genes down-regulated in comparison of control dendritic cells (DC) at 2 h versus those stimulated with Gardiquimod (TLR7 agonist) at 2 h. MSigDB C7: Immunologic Signatures (v6.0) 6.282E-6 2.990E-3 2.017E-2 2.990E-3 3 200
2 M2660 Genes up-regulated in late serum response of CRL 2091 cells (foreskin fibroblasts). MSigDB C6: Oncogenic Signatures (v6.0) 5.414E-4 2.046E-2
1.380E-1
2.577E-1
 2 172
3 M8577 Genes down-regulated in MCF7 cells (breast cancer) engineered to conditionally express a dominant negative form of CLIM2 [GeneID=8861] by a Tet Off system. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.327E-4 2.046E-2
1.380E-1
3.011E-1
 2 186
4 17150101-TableS1f Human Breast Troester06 3genes-up DOX-ME16C GeneSigDB 6.482E-4 2.046E-2
1.380E-1
3.085E-1
 1 3
5 M4250 Genes down-regulated in comparison of CD4 [GeneID=920] T cells treated with IL4 [GeneID=3565] and anti-IL12 at 2 h versus those at 72 h. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 2.046E-2
1.380E-1
3.444E-1
 2 199
6 M5513 Genes up-regulated in comparison of macrophages versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 2.046E-2
1.380E-1
3.444E-1
 2 199
7 M3404 Genes up-regulated in comparison of control microglia cells versus those 6 h after stimulation with IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
8 M5474 Genes up-regulated in comparison of dendritic cells (DC) versus effector memory CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
9 M3971 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 6 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
10 M3716 Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with poly(I:C) (TLR3 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
11 M7276 Genes down-regulated in double positve thymocyte: TCF3 [GeneID=6929] knockout versus TCF3 and TCF12 [GeneID=6929;6938] knockout. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
12 M3765 Genes down-regulated in comparison of control dendritic cells (DC) at 6 h versus those stimulated with CpG DNA (TLR9 agonist) at 6 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
13 M4097 Genes down-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 0.5 h versus those stimulated at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
14 M5620 Genes up-regulated in comparison of CD4 [GeneID=920] T cells treated with TGFB3 [GeneID=7043] and IL6 [GeneID=3569] versus those treated with TGF3B [GeneID=7043], IL6 [GeneID=3569] and IL23A [GeneID=51561]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
15 M7232 Genes down-regulated in T cells treated with IL21 [GeneID=59067]: 1h versus 6h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
16 M3690 Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
17 M4073 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus those stimulated at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 2.046E-2
1.380E-1
3.479E-1
 2 200
18 M9183 Pre-mitotic cell cycle regulators (CDC) identified in an shRNA screen of the ubiquitin pathway components. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.375E-3 4.885E-2
3.294E-1
1.000E0
 1 11
19 19325563-Table2b Rat Heart GallegoDelgado09 19genes GeneSigDB 2.591E-3 4.885E-2
3.294E-1
1.000E0
 1 12
20 M3990 Cluster d1: genes down-regulated in WS1 cells (fibroblast) at 6 h after irradiation with high dose UV-C. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.884E-3 4.885E-2
3.294E-1
1.000E0
 1 18
21 15388584-Table5 Human BoneMarrow Abraham05 20genes GeneSigDB 3.884E-3 4.885E-2
3.294E-1
1.000E0
 1 18
22 M2051 Top genes associated with chemosensitivity to cyclophosphamide [PubChem=2907] across 85 tumor xenografts. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.884E-3 4.885E-2
3.294E-1
1.000E0
 1 18
23 M9880 Genes down-regulated in immunoglobulin light chain amyloidosis plasma cells (ALPC) compared to multiple myeloma (MM) cells. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.100E-3 4.885E-2
3.294E-1
1.000E0
 1 19
24 M9634 Cluster 4: genes changed in primary keratinocytes by UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.315E-3 4.885E-2
3.294E-1
1.000E0
 1 20
25 M16756 Genes down-regulated in primary keratinocytes at 6 h after UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.530E-3 4.885E-2
3.294E-1
1.000E0
 1 21
26 M6967 Up-regulated genes that separate angiogenic from non-angiogenic non-small cell lung carcinoma (NSCLC) samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.530E-3 4.885E-2
3.294E-1
1.000E0
 1 21
27 M8108 Genes up-regulated in MCF-7 cells (breast cancer) by selective estrogen receptor modulators (SERM) 4-hydroxytamoxifen, raloxifene, or ICI 182780 but not by estradiol [PubChem=44959;5035;3478439;5757]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.961E-3 4.885E-2
3.294E-1
1.000E0
 1 23
28 11694447-Figure4a Human Lung not cancer Temple01 29genes GeneSigDB 5.391E-3 4.885E-2
3.294E-1
1.000E0
 1 25
29 16232199-Table2 Human Brain Saigusa05 40genes GeneSigDB 5.822E-3 4.885E-2
3.294E-1
1.000E0
 1 27
30 M5516 Top 40 genes from cluster 12 of acute myeloid leukemia (AML) expression profile; 89% of the samples are FAB M3 subtype, 95% bear the t(15;17) translocation, all have the PML-RARA fusion [GeneID=5371;5914]; indicate good survival. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.467E-3 4.885E-2
3.294E-1
1.000E0
 1 30
31 15896717-Table7 Human Leukemia Bal05 36genes GeneSigDB 7.756E-3 4.885E-2
3.294E-1
1.000E0
 1 36
32 17213814-Table1 Human Ovarian Appierto07 41genes GeneSigDB 7.971E-3 4.885E-2
3.294E-1
1.000E0
 1 37
33 M9538 Genes up-regulated in rectal but down-regulated in colon carcinoma compared to normal mucosa samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.186E-3 4.885E-2
3.294E-1
1.000E0
 1 38
34 16935118-Table1 Human Lung Gordon06 38genes GeneSigDB 8.186E-3 4.885E-2
3.294E-1
1.000E0
 1 38
35 M1546 Genes up-regulated in A2780 cells (ovarian carcinoma) exposed to fenretinide [PubChem=1744]. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.186E-3 4.885E-2
3.294E-1
1.000E0
 1 38
36 M1760 Genes down-regulated after Cre-lox knockout of LSD1 [GeneID=23028] in pituitary. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.400E-3 4.885E-2
3.294E-1
1.000E0
 1 39
37 M5957 Genes specifically up-regulated in pancreatic beta cells. MSigDB H: Hallmark Gene Sets (v6.0) 8.615E-3 4.885E-2
3.294E-1
1.000E0
 1 40
38 M10850 Genes down-regulated in blister cells from patients with adverse drug reactions (ADR). MSigDB C2: CGP Curated Gene Sets (v6.0) 9.473E-3 4.885E-2
3.294E-1
1.000E0
 1 44
39 14722241-Table1b Human Lung Chen04 52genes GeneSigDB 9.688E-3 4.885E-2
3.294E-1
1.000E0
 1 45
40 16597596-TableS1-5 Human Leukemia Wilson06 50genes SigDifferentialClusterE GeneSigDB 1.012E-2 4.885E-2
3.294E-1
1.000E0
 1 47
41 16188652-table1a Human StemCell Shaughnessy05 51genes GeneSigDB 1.055E-2 4.885E-2
3.294E-1
1.000E0
 1 49
42 14735469-Table2 Human Breast Zhao04 58genes GeneSigDB 1.076E-2 4.885E-2
3.294E-1
1.000E0
 1 50
43 20368555-TS-3 Human Breast Barry10 52genes GeneSigDB 1.076E-2 4.885E-2
3.294E-1
1.000E0
 1 50
44 16280042-GeneList Human Breast Pawitan05 64genes prognosisGenes GeneSigDB 1.097E-2 4.885E-2
3.294E-1
1.000E0
 1 51
45 16356477-Table1 Human Breast Song06 62genes GeneSigDB 1.097E-2 4.885E-2
3.294E-1
1.000E0
 1 51
46 M12050 Genes up-regulated in hyppocampus of mice carrying a hemizygotic microdeletion in the 22q11.2 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.140E-2 4.885E-2
3.294E-1
1.000E0
 1 53
47 M2589 Cluster 2: genes changed in primary keratinocytes by UVB irradiation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.162E-2 4.885E-2
3.294E-1
1.000E0
 1 54
48 19965622-TableS2b Human LymphaticEndothelialCells Norrmen09 65genes GeneSigDB 1.183E-2 4.885E-2
3.294E-1
1.000E0
 1 55
49 16705456-Table2 Human Leukemia Cao06 56genes GeneSigDB 1.204E-2 4.885E-2
3.294E-1
1.000E0
 1 56
50 M1541 Genes down-regulated in NIH 3T3 cells (fibroblasts) 24 h after inducing MyoD [GeneID=4654] differentiation program. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.226E-2 4.885E-2
3.294E-1
1.000E0
 1 57
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 294 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 3 input genes in category / 18 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M13367 GNF2 TM4SF2 Neighborhood of TM4SF2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.752E-3 3.978E-2
1.390E-1
1.395E-1
 1 26
2 M3615 MODULE 303 Genes in the cancer module 303. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.347E-3 3.978E-2
1.390E-1
1.502E-1
 1 28
3 M15601 GNF2 RAB3A Neighborhood of RAB3A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.102E-2 3.978E-2
1.390E-1
1.984E-1
 1 37
4 M8546 GNF2 MAPT Neighborhood of MAPT MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.221E-2 3.978E-2
1.390E-1
2.197E-1
 1 41
5 M10137 GNF2 RTN1 Neighborhood of RTN1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.546E-2 3.978E-2
1.390E-1
2.783E-1
 1 52
6 M887 MORF REV3L Neighborhood of REV3L MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.694E-2 3.978E-2
1.390E-1
3.050E-1
 1 57
7 M8951 MORF RAB11A Neighborhood of RAB11A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.753E-2 3.978E-2
1.390E-1
3.156E-1
 1 59
8 M1566 MODULE 568 Genes in the cancer module 568. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.166E-2 3.978E-2
1.390E-1
3.899E-1
 1 73
9 M3373 GNF2 DNM1 Neighborhood of DNM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.166E-2 3.978E-2
1.390E-1
3.899E-1
 1 73
10 M15916 MODULE 491 Genes in the cancer module 491. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.343E-2 3.978E-2
1.390E-1
4.217E-1
 1 79
11 M9981 MORF PPP2R5E Neighborhood of PPP2R5E MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.431E-2 3.978E-2
1.390E-1
4.376E-1
 1 82
12 M13779 MODULE 157 Genes in the cancer module 157. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.194E-2 4.791E-2
1.674E-1
5.749E-1
 1 108
Show 7 more annotations

16: MicroRNA [Display Chart] 5 input genes in category / 113 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-378a-3p:Functional MTI Functional MTI miRTarbase 5.162E-5 3.588E-3 1.905E-2 5.833E-3 2 165
2 hsa-miR-431*:mirSVR highEffct hsa-miR-431*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.350E-5 3.588E-3 1.905E-2 7.176E-3 2 183
3 CAGTGTT,MIR-200A:MSigDB CAGTGTT,MIR-200A:MSigDB MSigDB 1.604E-4 4.532E-3 2.406E-2 1.813E-2 2 291
4 CAGTGTT,MIR-141:MSigDB CAGTGTT,MIR-141:MSigDB MSigDB 1.604E-4 4.532E-3 2.406E-2 1.813E-2 2 291
5 hsa-miR-768-3p:PITA hsa-miR-768-3p:PITA TOP PITA 2.438E-4 5.511E-3 2.926E-2 2.755E-2 2 359
6 hsa-miR-485-3p:PITA hsa-miR-485-3p:PITA TOP PITA 3.365E-4 6.337E-3 3.364E-2 3.802E-2 2 422
7 hsa-miR-618:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.111E-3 3.328E-2
1.767E-1
3.515E-1
 1 45
8 hsa-miR-3129-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.801E-3 3.328E-2
1.767E-1
4.295E-1
 1 55
9 hsa-miR-5583-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.870E-3 3.328E-2
1.767E-1
4.373E-1
 1 56
10 hsa-miR-6779-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.146E-3 3.328E-2
1.767E-1
4.685E-1
 1 60
11 AAGTCCA,MIR-422A:MSigDB AAGTCCA,MIR-422A:MSigDB MSigDB 4.422E-3 3.328E-2
1.767E-1
4.997E-1
 1 64
12 AAGTCCA,MIR-422B:MSigDB AAGTCCA,MIR-422B:MSigDB MSigDB 4.422E-3 3.328E-2
1.767E-1
4.997E-1
 1 64
13 hsa-miR-3128:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.767E-3 3.328E-2
1.767E-1
5.386E-1
 1 69
14 hsa-miR-4714-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.836E-3 3.328E-2
1.767E-1
5.464E-1
 1 70
15 hsa-miR-4424:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 3.328E-2
1.767E-1
5.854E-1
 1 75
16 hsa-miR-1226-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.594E-3 3.328E-2
1.767E-1
6.321E-1
 1 81
17 hsa-miR-4470:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.663E-3 3.328E-2
1.767E-1
6.399E-1
 1 82
18 hsa-miR-617:PITA hsa-miR-617:PITA TOP PITA 6.833E-3 3.328E-2
1.767E-1
7.722E-1
 1 99
19 hsa-miR-6834-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.902E-3 3.328E-2
1.767E-1
7.800E-1
 1 100
20 GCTTGAA,MIR-498:MSigDB GCTTGAA,MIR-498:MSigDB MSigDB 7.315E-3 3.328E-2
1.767E-1
8.266E-1
 1 106
21 hsa-miR-4650-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.659E-3 3.328E-2
1.767E-1
8.655E-1
 1 111
22 hsa-miR-610:PITA hsa-miR-610:PITA TOP PITA 8.278E-3 3.328E-2
1.767E-1
9.354E-1
 1 120
23 hsa-miR-4689:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.759E-3 3.328E-2
1.767E-1
9.898E-1
 1 127
24 hsa-miR-6734-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.966E-3 3.328E-2
1.767E-1
1.000E0
 1 130
25 hsa-miR-6858-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.034E-3 3.328E-2
1.767E-1
1.000E0
 1 131
26 hsa-miR-6738-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.240E-3 3.328E-2
1.767E-1
1.000E0
 1 134
27 hsa-miR-1304-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.309E-3 3.328E-2
1.767E-1
1.000E0
 1 135
28 hsa-miR-5194:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.309E-3 3.328E-2
1.767E-1
1.000E0
 1 135
29 hsa-miR-8073:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.515E-3 3.328E-2
1.767E-1
1.000E0
 1 138
30 hsa-miR-1914-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.721E-3 3.328E-2
1.767E-1
1.000E0
 1 141
31 hsa-miR-221-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.927E-3 3.328E-2
1.767E-1
1.000E0
 1 144
32 hsa-miR-544a:Functional MTI Functional MTI miRTarbase 1.041E-2 3.328E-2
1.767E-1
1.000E0
 1 151
33 hsa-miR-197:PITA hsa-miR-197:PITA TOP PITA 1.048E-2 3.328E-2
1.767E-1
1.000E0
 1 152
34 hsa-miR-147:PITA hsa-miR-147:PITA TOP PITA 1.061E-2 3.328E-2
1.767E-1
1.000E0
 1 154
35 hsa-miR-758:PITA hsa-miR-758:PITA TOP PITA 1.068E-2 3.328E-2
1.767E-1
1.000E0
 1 155
36 hsa-let-7i*:mirSVR highEffct hsa-let-7i*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.068E-2 3.328E-2
1.767E-1
1.000E0
 1 155
37 hsa-miR-943:PITA hsa-miR-943:PITA TOP PITA 1.103E-2 3.328E-2
1.767E-1
1.000E0
 1 160
38 hsa-miR-1265:PITA hsa-miR-1265:PITA TOP PITA 1.171E-2 3.328E-2
1.767E-1
1.000E0
 1 170
39 hsa-miR-1206:PITA hsa-miR-1206:PITA TOP PITA 1.205E-2 3.328E-2
1.767E-1
1.000E0
 1 175
40 hsa-miR-521:mirSVR highEffct hsa-miR-521:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.233E-2 3.328E-2
1.767E-1
1.000E0
 1 179
41 hsa-miR-3927-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.267E-2 3.328E-2
1.767E-1
1.000E0
 1 184
42 hsa-miR-3184-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.274E-2 3.328E-2
1.767E-1
1.000E0
 1 185
43 hsa-miR-6831-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.281E-2 3.328E-2
1.767E-1
1.000E0
 1 186
44 hsa-miR-630:PITA hsa-miR-630:PITA TOP PITA 1.370E-2 3.328E-2
1.767E-1
1.000E0
 1 199
45 AAAGGGA,MIR-211:MSigDB AAAGGGA,MIR-211:MSigDB MSigDB 1.452E-2 3.328E-2
1.767E-1
1.000E0
 1 211
46 AAAGGGA,MIR-204:MSigDB AAAGGGA,MIR-204:MSigDB MSigDB 1.452E-2 3.328E-2
1.767E-1
1.000E0
 1 211
47 hsa-miR-143:PITA hsa-miR-143:PITA TOP PITA 1.513E-2 3.328E-2
1.767E-1
1.000E0
 1 220
48 hsa-miR-1272:PITA hsa-miR-1272:PITA TOP PITA 1.513E-2 3.328E-2
1.767E-1
1.000E0
 1 220
49 hsa-miR-3150b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.582E-2 3.328E-2
1.767E-1
1.000E0
 1 230
50 hsa-miR-4784:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.589E-2 3.328E-2
1.767E-1
1.000E0
 1 231
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 566 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID011040840 CID11040840 Stitch 2.189E-4 3.097E-2
2.142E-1
1.239E-1
 1 1
2 DB07364 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINE Drug Bank 2.189E-4 3.097E-2
2.142E-1
1.239E-1
 1 1
3 CID000355392 NSC-608832 Stitch 4.378E-4 3.097E-2
2.142E-1
2.478E-1
 1 2
4 CID000014624 5-benzyloxyindole Stitch 6.566E-4 3.097E-2
2.142E-1
3.716E-1
 1 3
5 CID000086260 cdE2 Stitch 6.566E-4 3.097E-2
2.142E-1
3.716E-1
 1 3
6 CID000403994 CDK1 inhibitor III Stitch 6.566E-4 3.097E-2
2.142E-1
3.716E-1
 1 3
7 DB03428 SU9516 Drug Bank 6.566E-4 3.097E-2
2.142E-1
3.716E-1
 1 3
8 DB02950 Hymenialdisine Drug Bank 6.566E-4 3.097E-2
2.142E-1
3.716E-1
 1 3
9 1580 UP Furosemide [54-31-9]; Up 200; 12uM; HL60; HG-U133A Broad Institute CMAP Up 6.913E-4 3.097E-2
2.142E-1
3.913E-1
 2 192
10 23 UP 2-propylpentanoic acid; Up 200; 1000uM; MCF7; HG-U133A Broad Institute CMAP Up 6.913E-4 3.097E-2
2.142E-1
3.913E-1
 2 192
11 1732 UP Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; HL60; HG-U133A Broad Institute CMAP Up 7.130E-4 3.097E-2
2.142E-1
4.035E-1
 2 195
12 1903 DN Oxethazaine [126-27-2]; Down 200; 8.6uM; PC3; HG-U133A Broad Institute CMAP Down 7.276E-4 3.097E-2
2.142E-1
4.118E-1
 2 197
13 1559 UP Spiperone [749-02-0]; Up 200; 10.2uM; HL60; HG-U133A Broad Institute CMAP Up 7.498E-4 3.097E-2
2.142E-1
4.244E-1
 2 200
14 DB04014 Alsterpaullone Drug Bank 8.754E-4 3.097E-2
2.142E-1
4.955E-1
 1 4
15 DB02052 Indirubin-3'-Monoxime Drug Bank 8.754E-4 3.097E-2
2.142E-1
4.955E-1
 1 4
16 DB02116 Olomoucine Drug Bank 8.754E-4 3.097E-2
2.142E-1
4.955E-1
 1 4
17 CID000005097 NSC683246 Stitch 1.024E-3 3.174E-2
2.196E-1
5.796E-1
 2 234
18 CID000382948 AC1L8KDV Stitch 1.094E-3 3.174E-2
2.196E-1
6.193E-1
 1 5
19 CID011355490 3-isothiocyanatobutanal Stitch 1.094E-3 3.174E-2
2.196E-1
6.193E-1
 1 5
20 ctd:D008094 Lithium CTD 1.122E-3 3.174E-2
2.196E-1
6.349E-1
 2 245
21 CID000004625 AC1L1IL4 Stitch 1.313E-3 3.538E-2
2.447E-1
7.431E-1
 1 6
22 ctd:D012524 Sarin CTD 1.524E-3 3.612E-2
2.498E-1
8.625E-1
 2 286
23 CID006918409 Ro 63-1908 Stitch 1.532E-3 3.612E-2
2.498E-1
8.668E-1
 1 7
24 CID005353653 GW8510 Stitch 1.532E-3 3.612E-2
2.498E-1
8.668E-1
 1 7
25 ctd:C512484 AG-012986 CTD 1.750E-3 3.810E-2
2.635E-1
9.906E-1
 1 8
26 CID002777991 i 143 Stitch 1.750E-3 3.810E-2
2.635E-1
9.906E-1
 1 8
27 CID005317284 eupafolin Stitch 1.969E-3 3.838E-2
2.654E-1
1.000E0
 1 9
28 CID006918386 CVT-313 Stitch 1.969E-3 3.838E-2
2.654E-1
1.000E0
 1 9
29 CID001550489 2-mercaptopyrimidine Stitch 1.969E-3 3.838E-2
2.654E-1
1.000E0
 1 9
30 ctd:D005473 Fluoxetine CTD 2.034E-3 3.838E-2
2.654E-1
1.000E0
 2 331
31 DB03496 Flavopiridol Drug Bank 2.187E-3 3.994E-2
2.762E-1
1.000E0
 1 10
32 CID006857712 SNJ-1945 Stitch 2.624E-3 4.234E-2
2.929E-1
1.000E0
 1 12
33 CID000069481 glycylglycylglycylglycine Stitch 2.624E-3 4.234E-2
2.929E-1
1.000E0
 1 12
34 CID000002608 PNU 112455A Stitch 2.624E-3 4.234E-2
2.929E-1
1.000E0
 1 12
35 ctd:C017906 3-dinitrobenzene CTD 2.811E-3 4.234E-2
2.929E-1
1.000E0
 2 390
36 ctd:D003024 Clozapine CTD 2.839E-3 4.234E-2
2.929E-1
1.000E0
 2 392
37 ctd:C517828 hexabrominated diphenyl ether 153 CTD 2.843E-3 4.234E-2
2.929E-1
1.000E0
 1 13
38 CID005326843 aloisine A Stitch 2.843E-3 4.234E-2
2.929E-1
1.000E0
 1 13
39 CID000512292 iso-olomoucine Stitch 3.061E-3 4.332E-2
2.996E-1
1.000E0
 1 14
40 ctd:C559145 7-benzylamino-5-(2-(hydroxymethyl)propyl)amino-3-isopropyl-1(2)H-pyrazolo(4,3-d)pyrimidine CTD 3.061E-3 4.332E-2
2.996E-1
1.000E0
 1 14
41 CID003421919 Tyr-Phe Stitch 3.280E-3 4.420E-2
3.057E-1
1.000E0
 1 15
42 CID000449311 1 IN Stitch 3.280E-3 4.420E-2
3.057E-1
1.000E0
 1 15
43 CID000006195 naphthaldehyde Stitch 3.498E-3 4.573E-2
3.163E-1
1.000E0
 1 16
44 CID009885817 Calpain Inhibitor Vi Stitch 3.716E-3 4.573E-2
3.163E-1
1.000E0
 1 17
45 ctd:C100442 PD 150606 CTD 3.716E-3 4.573E-2
3.163E-1
1.000E0
 1 17
46 CID000025566 AT-8 Stitch 3.716E-3 4.573E-2
3.163E-1
1.000E0
 1 17
47 CID003009741 AC1MHQTP Stitch 3.934E-3 4.639E-2
3.209E-1
1.000E0
 1 18
48 CID000023969 arsonium Stitch 3.934E-3 4.639E-2
3.209E-1
1.000E0
 1 18
49 CID000369401 paullone Stitch 4.371E-3 4.692E-2
3.245E-1
1.000E0
 1 20
50 CID016073041 (3Z)-3-[3-(hydroxyamino)indolin-2-ylidene]oxindole Stitch 4.589E-3 4.692E-2
3.245E-1
1.000E0
 1 21
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 134 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 OMIN:612164 EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 4 OMIM 3.085E-4 8.269E-3 4.530E-2 4.135E-2 1 1
2 C0393699 Symptomatic Infantile Spasms DisGeNET BeFree 3.085E-4 8.269E-3 4.530E-2 4.135E-2 1 1
3 C1969156 Burst suppression on EEG DisGeNET Curated 3.085E-4 8.269E-3 4.530E-2 4.135E-2 1 1
4 cv:C2677326 Early infantile epileptic encephalopathy 4 Clinical Variations 3.085E-4 8.269E-3 4.530E-2 4.135E-2 1 1
5 C2677326 Epileptic Encephalopathy, Early Infantile, 4 DisGeNET Curated 3.085E-4 8.269E-3 4.530E-2 4.135E-2 1 1
6 C1527366 Salaam Seizures DisGeNET Curated 6.170E-4 1.378E-2
7.550E-2
8.268E-2
 1 2
7 C1856408 Infantile encephalopathy DisGeNET Curated 9.254E-4 1.503E-2
8.234E-2
1.240E-1
 1 3
8 C3150705 FOXG1 syndrome DisGeNET Curated 9.254E-4 1.503E-2
8.234E-2
1.240E-1
 1 3
9 C0677936 Refractory cancer DisGeNET BeFree 1.109E-3 1.503E-2
8.234E-2
1.487E-1
 2 173
10 C1264040 von Willebrand Disease, Type 2 DisGeNET Curated 1.234E-3 1.503E-2
8.234E-2
1.653E-1
 1 4
11 C4274995 Lissencephaly with cerebellar hypoplasia DisGeNET BeFree 1.234E-3 1.503E-2
8.234E-2
1.653E-1
 1 4
12 C0239815 Clenched hands DisGeNET Curated 1.850E-3 1.907E-2
1.045E-1
2.479E-1
 1 6
13 C1866753 Impaired horizontal smooth pursuit DisGeNET Curated 1.850E-3 1.907E-2
1.045E-1
2.479E-1
 1 6
14 C4023511 Obtundation status DisGeNET Curated 2.158E-3 2.066E-2
1.132E-1
2.892E-1
 1 7
15 C1836508 Hypertonic seizures DisGeNET Curated 2.466E-3 2.203E-2
1.207E-1
3.305E-1
 1 8
16 C0752323 Focal Clonic Seizures DisGeNET Curated 2.774E-3 2.323E-2
1.273E-1
3.717E-1
 1 9
17 C2677328 Brain hypomyelination DisGeNET Curated 3.390E-3 2.524E-2
1.383E-1
4.542E-1
 1 11
18 C4025231 Chronic calcifying pancreatitis DisGeNET BeFree 3.390E-3 2.524E-2
1.383E-1
4.542E-1
 1 11
19 C1264039 von Willebrand Disease, Type 1 DisGeNET Curated 4.005E-3 2.556E-2
1.400E-1
5.367E-1
 1 13
20 C1848199 X-Linked Lissencephaly DisGeNET Curated 4.005E-3 2.556E-2
1.400E-1
5.367E-1
 1 13
21 C2931919 X-linked infantile spasm syndrome DisGeNET BeFree 4.005E-3 2.556E-2
1.400E-1
5.367E-1
 1 13
22 C0037763 Spasm DisGeNET Curated 4.313E-3 2.627E-2
1.439E-1
5.779E-1
 1 14
23 C0007274 Carotid Artery Thrombosis DisGeNET Curated 4.620E-3 2.692E-2
1.475E-1
6.191E-1
 1 15
24 C1879312 Agyria DisGeNET Curated 4.928E-3 2.751E-2
1.507E-1
6.603E-1
 1 16
25 C3711387 Autosomal Recessive Primary Microcephaly DisGeNET BeFree 5.849E-3 3.093E-2
1.695E-1
7.838E-1
 1 19
26 C0240278 Lymphatic obstruction DisGeNET Curated 6.464E-3 3.093E-2
1.695E-1
8.661E-1
 1 21
27 C1835229 Onset of lymphedema around puberty DisGeNET Curated 6.464E-3 3.093E-2
1.695E-1
8.661E-1
 1 21
28 C1855106 Neonatal onset DisGeNET Curated 6.464E-3 3.093E-2
1.695E-1
8.661E-1
 1 21
29 C1838979 MITOCHONDRIAL COMPLEX I DEFICIENCY DisGeNET Curated 6.770E-3 3.128E-2
1.714E-1
9.072E-1
 1 22
30 C0393706 Early infantile epileptic encephalopathy with suppression bursts DisGeNET Curated 7.077E-3 3.161E-2
1.732E-1
9.484E-1
 1 23
31 C0684276 Hypsarrhythmia DisGeNET Curated 7.691E-3 3.221E-2
1.764E-1
1.000E0
 1 25
32 C0751122 Infantile Severe Myoclonic Epilepsy DisGeNET Curated 7.691E-3 3.221E-2
1.764E-1
1.000E0
 1 25
33 C0220603 childhood brain tumor DisGeNET BeFree 8.304E-3 3.372E-2
1.847E-1
1.000E0
 1 27
34 C0751214 Hyperalgesia, Thermal DisGeNET BeFree 8.917E-3 3.514E-2
1.925E-1
1.000E0
 1 29
35 C0266463 Lissencephaly DisGeNET Curated 1.045E-2 4.000E-2
2.192E-1
1.000E0
 1 34
36 C0042974 von Willebrand Disease DisGeNET BeFree 1.075E-2 4.003E-2
2.193E-1
1.000E0
 1 35
37 C3887898 Infantile Spasm DisGeNET Curated 1.137E-2 4.029E-2
2.207E-1
1.000E0
 1 37
38 C4021759 Generalized myoclonic seizures DisGeNET Curated 1.198E-2 4.029E-2
2.207E-1
1.000E0
 1 39
39 C0426970 Spastic Quadriplegia DisGeNET Curated 1.198E-2 4.029E-2
2.207E-1
1.000E0
 1 39
40 C0024236 Lymphedema DisGeNET Curated 1.320E-2 4.029E-2
2.207E-1
1.000E0
 1 43
41 C0746940 nonverbal DisGeNET Curated 1.320E-2 4.029E-2
2.207E-1
1.000E0
 1 43
42 C1854882 Absent speech DisGeNET Curated 1.320E-2 4.029E-2
2.207E-1
1.000E0
 1 43
43 C1837397 Global developmental delay, severe DisGeNET Curated 1.442E-2 4.029E-2
2.207E-1
1.000E0
 1 47
44 C0019572 Hirsutism DisGeNET Curated 1.442E-2 4.029E-2
2.207E-1
1.000E0
 1 47
45 C1854919 Severe psychomotor retardation DisGeNET Curated 1.442E-2 4.029E-2
2.207E-1
1.000E0
 1 47
46 C1504404 Hippocampal sclerosis DisGeNET BeFree 1.503E-2 4.029E-2
2.207E-1
1.000E0
 1 49
47 C1866231 Full cheeks DisGeNET Curated 1.533E-2 4.029E-2
2.207E-1
1.000E0
 1 50
48 C2748653 Chubby cheeks DisGeNET Curated 1.533E-2 4.029E-2
2.207E-1
1.000E0
 1 50
49 C4280647 Hypertrophy of cheeks DisGeNET Curated 1.533E-2 4.029E-2
2.207E-1
1.000E0
 1 50
50 C3806443 Puffy cheeks DisGeNET Curated 1.533E-2 4.029E-2
2.207E-1
1.000E0
 1 50
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