Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc371_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 16 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005243 gap junction channel activity 2.355E-12 3.767E-11 1.274E-10 3.767E-11 4 17
2 GO:0022829 wide pore channel activity 1.251E-11 1.001E-10 3.384E-10 2.002E-10 4 25
3 GO:0015267 channel activity 1.947E-6 7.856E-6 2.656E-5 3.116E-5 4 470
4 GO:0022803 passive transmembrane transporter activity 1.964E-6 7.856E-6 2.656E-5 3.142E-5 4 471
5 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling 5.358E-4 1.429E-3 4.831E-3 8.573E-3 1 2
6 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling 5.358E-4 1.429E-3 4.831E-3 8.573E-3 1 2
7 GO:0071253 connexin binding 1.339E-3 3.061E-3 1.035E-2 2.143E-2 1 5
8 GO:0030280 structural constituent of epidermis 2.142E-3 4.284E-3 1.448E-2 3.427E-2 1 8
9 GO:0048487 beta-tubulin binding 1.094E-2 1.945E-2
6.574E-2
1.750E-1
 1 41
10 GO:0097110 scaffold protein binding 1.465E-2 2.344E-2
7.925E-2
2.344E-1
 1 55
11 GO:0005200 structural constituent of cytoskeleton 2.913E-2 4.003E-2
1.353E-1
4.661E-1
 1 110
12 GO:0030165 PDZ domain binding 3.018E-2 4.003E-2
1.353E-1
4.828E-1
 1 114
13 GO:0017124 SH3 domain binding 3.253E-2 4.003E-2
1.353E-1
5.205E-1
 1 123
14 GO:0030674 protein binding, bridging 4.292E-2 4.905E-2
1.658E-1
6.868E-1
 1 163
Show 9 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 284 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016264 gap junction assembly 2.043E-9 5.801E-7 3.613E-6 5.801E-7 3 12
2 GO:0007043 cell-cell junction assembly 1.277E-6 1.813E-4 1.129E-3 3.625E-4 3 95
3 GO:0015868 purine ribonucleotide transport 2.075E-6 1.964E-4 1.223E-3 5.892E-4 2 9
4 GO:0015865 purine nucleotide transport 3.169E-6 2.250E-4 1.401E-3 8.999E-4 2 11
5 GO:0034329 cell junction assembly 1.201E-5 6.822E-4 4.249E-3 3.411E-3 3 200
6 GO:0045216 cell-cell junction organization 1.826E-5 7.585E-4 4.724E-3 5.185E-3 3 230
7 GO:0006862 nucleotide transport 1.869E-5 7.585E-4 4.724E-3 5.309E-3 2 26
8 GO:0034330 cell junction organization 2.575E-5 9.141E-4 5.693E-3 7.313E-3 3 258
9 GO:1901264 carbohydrate derivative transport 8.830E-5 2.786E-3 1.735E-2 2.508E-2 2 56
10 GO:0015748 organophosphate ester transport 2.443E-4 6.354E-3 3.957E-2
6.938E-2
 2 93
11 GO:0060156 milk ejection reflex 2.685E-4 6.354E-3 3.957E-2
7.625E-2
 1 1
12 GO:0010232 vascular transport 2.685E-4 6.354E-3 3.957E-2
7.625E-2
 1 1
13 GO:0010652 positive regulation of cell communication by chemical coupling 5.369E-4 8.975E-3
5.590E-2
1.525E-1
 1 2
14 GO:0003294 atrial ventricular junction remodeling 5.369E-4 8.975E-3
5.590E-2
1.525E-1
 1 2
15 GO:0010645 regulation of cell communication by chemical coupling 5.369E-4 8.975E-3
5.590E-2
1.525E-1
 1 2
16 GO:0044752 response to human chorionic gonadotropin 5.369E-4 8.975E-3
5.590E-2
1.525E-1
 1 2
17 GO:0001508 action potential 5.372E-4 8.975E-3
5.590E-2
1.526E-1
 2 138
18 GO:0010643 cell communication by chemical coupling 8.053E-4 1.204E-2
7.496E-2
2.287E-1
 1 3
19 GO:0003347 epicardial cell to mesenchymal cell transition 8.053E-4 1.204E-2
7.496E-2
2.287E-1
 1 3
20 GO:0003104 positive regulation of glomerular filtration 1.074E-3 1.525E-2
9.495E-2
3.049E-1
 1 4
21 GO:0015931 nucleobase-containing compound transport 1.297E-3 1.657E-2
1.032E-1
3.682E-1
 2 215
22 GO:2000987 positive regulation of behavioral fear response 1.342E-3 1.657E-2
1.032E-1
3.811E-1
 1 5
23 GO:1903367 positive regulation of fear response 1.342E-3 1.657E-2
1.032E-1
3.811E-1
 1 5
24 GO:0015867 ATP transport 1.610E-3 1.759E-2
1.095E-1
4.573E-1
 1 6
25 GO:2000822 regulation of behavioral fear response 1.610E-3 1.759E-2
1.095E-1
4.573E-1
 1 6
26 GO:1903365 regulation of fear response 1.610E-3 1.759E-2
1.095E-1
4.573E-1
 1 6
27 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization 1.878E-3 1.976E-2
1.230E-1
5.334E-1
 1 7
28 GO:0060371 regulation of atrial cardiac muscle cell membrane depolarization 2.146E-3 2.177E-2
1.356E-1
6.095E-1
 1 8
29 GO:0051503 adenine nucleotide transport 2.414E-3 2.364E-2
1.472E-1
6.857E-1
 1 9
30 GO:0060312 regulation of blood vessel remodeling 2.950E-3 2.793E-2
1.739E-1
8.378E-1
 1 11
31 GO:0060044 negative regulation of cardiac muscle cell proliferation 3.218E-3 2.856E-2
1.779E-1
9.139E-1
 1 12
32 GO:0003093 regulation of glomerular filtration 3.218E-3 2.856E-2
1.779E-1
9.139E-1
 1 12
33 GO:2000810 regulation of bicellular tight junction assembly 3.754E-3 2.961E-2
1.844E-1
1.000E0
 1 14
34 GO:0086026 atrial cardiac muscle cell to AV node cell signaling 3.754E-3 2.961E-2
1.844E-1
1.000E0
 1 14
35 GO:0086066 atrial cardiac muscle cell to AV node cell communication 3.754E-3 2.961E-2
1.844E-1
1.000E0
 1 14
36 GO:0086014 atrial cardiac muscle cell action potential 3.754E-3 2.961E-2
1.844E-1
1.000E0
 1 14
37 GO:0042391 regulation of membrane potential 4.216E-3 3.114E-2
1.939E-1
1.000E0
 2 391
38 GO:0007512 adult heart development 4.556E-3 3.114E-2
1.939E-1
1.000E0
 1 17
39 GO:0055022 negative regulation of cardiac muscle tissue growth 4.556E-3 3.114E-2
1.939E-1
1.000E0
 1 17
40 GO:0061117 negative regulation of heart growth 4.556E-3 3.114E-2
1.939E-1
1.000E0
 1 17
41 GO:0099625 ventricular cardiac muscle cell membrane repolarization 4.824E-3 3.114E-2
1.939E-1
1.000E0
 1 18
42 GO:0001977 renal system process involved in regulation of blood volume 4.824E-3 3.114E-2
1.939E-1
1.000E0
 1 18
43 GO:0015858 nucleoside transport 4.824E-3 3.114E-2
1.939E-1
1.000E0
 1 18
44 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization 4.824E-3 3.114E-2
1.939E-1
1.000E0
 1 18
45 GO:0002070 epithelial cell maturation 5.091E-3 3.213E-2
2.001E-1
1.000E0
 1 19
46 GO:0099623 regulation of cardiac muscle cell membrane repolarization 5.626E-3 3.395E-2
2.115E-1
1.000E0
 1 21
47 GO:0086064 cell communication by electrical coupling involved in cardiac conduction 5.893E-3 3.395E-2
2.115E-1
1.000E0
 1 22
48 GO:0055026 negative regulation of cardiac muscle tissue development 6.428E-3 3.395E-2
2.115E-1
1.000E0
 1 24
49 GO:0003094 glomerular filtration 6.428E-3 3.395E-2
2.115E-1
1.000E0
 1 24
50 GO:0060004 reflex 6.428E-3 3.395E-2
2.115E-1
1.000E0
 1 24
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 29 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005922 connexin complex 4.403E-12 1.277E-10 5.058E-10 1.277E-10 4 20
2 GO:0005921 gap junction 4.212E-11 6.107E-10 2.420E-9 1.221E-9 4 34
3 GO:0005911 cell-cell junction 1.120E-6 1.083E-5 4.291E-5 3.249E-5 4 418
4 GO:0016328 lateral plasma membrane 7.545E-5 5.470E-4 2.167E-3 2.188E-3 2 53
5 GO:0005916 fascia adherens 3.406E-3 1.975E-2
7.826E-2
9.877E-2
 1 13
6 GO:0005771 multivesicular body 1.201E-2 4.873E-2
1.931E-1
3.483E-1
 1 46
7 GO:0001533 cornified envelope 1.253E-2 4.873E-2
1.931E-1
3.633E-1
 1 48
8 GO:0030660 Golgi-associated vesicle membrane 1.383E-2 4.873E-2
1.931E-1
4.010E-1
 1 53
9 GO:0014704 intercalated disc 1.512E-2 4.873E-2
1.931E-1
4.386E-1
 1 58
10 GO:0005913 cell-cell adherens junction 1.771E-2 4.874E-2
1.931E-1
5.137E-1
 1 68
11 GO:0044291 cell-cell contact zone 1.849E-2 4.874E-2
1.931E-1
5.362E-1
 1 71
Show 6 more annotations

4: Human Phenotype [Display Chart] 4 input genes in category / 628 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0007465 Honeycomb palmoplantar keratoderma 1.625E-6 1.020E-3 7.163E-3 1.020E-3 2 3
2 HP:0025114 Hypergranulosis 3.565E-5 6.613E-3 4.643E-2 2.239E-2 2 12
3 HP:0009775 Amniotic constriction ring 4.212E-5 6.613E-3 4.643E-2 2.645E-2 2 13
4 HP:0011409 Abnormality of placental membranes 4.212E-5 6.613E-3 4.643E-2 2.645E-2 2 13
5 HP:0008404 Nail dystrophy 8.644E-5 1.055E-2
7.408E-2
5.428E-2
 3 133
6 HP:0000982 Palmoplantar keratoderma 1.008E-4 1.055E-2
7.408E-2
6.331E-2
 3 140
7 HP:0008391 Dystrophic fingernails 1.244E-4 1.116E-2
7.837E-2
7.814E-2
 2 22
8 HP:0005595 Generalized hyperkeratosis 2.183E-4 1.713E-2
1.203E-1
1.371E-1
 2 29
9 HP:0002164 Nail dysplasia 2.886E-4 1.977E-2
1.388E-1
1.812E-1
 3 199
10 HP:0005750 Contractures of the joints of the lower limbs 4.558E-4 1.977E-2
1.388E-1
2.862E-1
 3 232
11 HP:0000962 Hyperkeratosis 5.491E-4 1.977E-2
1.388E-1
3.448E-1
 3 247
12 HP:0000972 Palmoplantar hyperkeratosis 5.782E-4 1.977E-2
1.388E-1
3.631E-1
 2 47
13 HP:0001035 Abnormality of keratinization 5.828E-4 1.977E-2
1.388E-1
3.660E-1
 3 252
14 HP:0010765 Palmar hyperkeratosis 6.812E-4 1.977E-2
1.388E-1
4.278E-1
 2 51
15 HP:0007556 Plantar hyperkeratosis 7.638E-4 1.977E-2
1.388E-1
4.797E-1
 2 54
16 HP:0003121 Limb joint contracture 8.484E-4 1.977E-2
1.388E-1
5.328E-1
 3 286
17 HP:0011622 Inlet ventricular septal defect 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
18 HP:0004281 Irregular sclerosis of hand bones 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
19 HP:0009162 Absent middle phalanx of 5th finger 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
20 HP:0009772 Patchy sclerosis of finger phalanx 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
21 HP:0005768 2-4 toe cutaneous syndactyly 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
22 HP:0009238 Aplasia of the 5th finger 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
23 HP:0005769 Fifth finger distal phalanx clinodactyly 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
24 HP:0004495 Thin anteverted nares 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
25 HP:0010705 4-5 finger syndactyly 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
26 HP:0004286 Patchy sclerosis of hand bones 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
27 HP:0008442 Vertebral hyperostosis 8.498E-4 1.977E-2
1.388E-1
5.337E-1
 1 1
28 HP:0000653 Sparse eyelashes 1.040E-3 2.332E-2
1.637E-1
6.530E-1
 2 63
29 HP:0002385 Paraparesis 1.141E-3 2.471E-2
1.735E-1
7.166E-1
 2 66
30 HP:0001194 Abnormalities of placenta or umbilical cord 1.512E-3 2.629E-2
1.845E-1
9.494E-1
 2 76
31 HP:0200102 Sparse or absent eyelashes 1.552E-3 2.629E-2
1.845E-1
9.744E-1
 2 77
32 HP:0001597 Abnormality of the nail 1.620E-3 2.629E-2
1.845E-1
1.000E0
 3 356
33 HP:0011617 Pulmonary situs ambiguus 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
34 HP:0010445 Primum atrial septal defect 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
35 HP:0005597 Congenital alopecia totalis 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
36 HP:0011615 Abnormal pulmonary situs morphology 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
37 HP:0004407 Bony paranasal bossing 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
38 HP:0006384 Club-shaped distal femur 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
39 HP:0012304 Hypoplastic aortic arch 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
40 HP:0012812 Fullness of paranasal tissue 1.699E-3 2.629E-2
1.845E-1
1.000E0
 1 2
41 HP:0001596 Alopecia 1.716E-3 2.629E-2
1.845E-1
1.000E0
 2 81
42 HP:0100872 Abnormality of the plantar skin of foot 2.116E-3 3.164E-2
2.221E-1
1.000E0
 2 90
43 HP:0011368 Epidermal thickening 2.217E-3 3.238E-2
2.273E-1
1.000E0
 3 396
44 HP:0002213 Fine hair 2.765E-3 3.887E-2
2.729E-1
1.000E0
 2 103
45 HP:0010549 Weakness due to upper motor neuron dysfunction 2.786E-3 3.887E-2
2.729E-1
1.000E0
 3 428
46 HP:0005686 Patchy osteosclerosis 3.396E-3 4.182E-2
2.936E-1
1.000E0
 1 4
47 HP:0009779 3-4 toe syndactyly 3.396E-3 4.182E-2
2.936E-1
1.000E0
 1 4
48 HP:0040162 Orthokeratosis 3.396E-3 4.182E-2
2.936E-1
1.000E0
 1 4
49 HP:0007930 Prominent epicanthal folds 3.396E-3 4.182E-2
2.936E-1
1.000E0
 1 4
50 HP:0011081 Incisor macrodontia 3.396E-3 4.182E-2
2.936E-1
1.000E0
 1 4
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 4 input genes in category / 462 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0010194 absent lymphatic vessels 2.349E-6 1.085E-3 7.286E-3 1.085E-3 2 7
2 MP:0003390 lymphedema 7.377E-6 1.704E-3 1.144E-2 3.408E-3 2 12
3 MP:0001879 abnormal lymphatic vessel morphology 3.590E-4 4.459E-2
2.994E-1
1.658E-1
 2 81
4 MP:0002796 impaired skin barrier function 4.531E-4 4.459E-2
2.994E-1
2.093E-1
 2 91
5 MP:0010477 coronary artery aneurysm 7.725E-4 4.459E-2
2.994E-1
3.569E-1
 1 2
6 MP:0003690 abnormal glial cell physiology 7.870E-4 4.459E-2
2.994E-1
3.636E-1
 2 120
7 MP:0030034 depressed nasal bridge 1.159E-3 4.459E-2
2.994E-1
5.352E-1
 1 3
8 MP:0002336 abnormal pulmonary gas exchange 1.159E-3 4.459E-2
2.994E-1
5.352E-1
 1 3
9 MP:0000887 delaminated cerebellar granule layer 1.159E-3 4.459E-2
2.994E-1
5.352E-1
 1 3
10 MP:0004482 abnormal interdental cell morphology 1.159E-3 4.459E-2
2.994E-1
5.352E-1
 1 3
11 MP:0002322 abnormal respiratory transport 1.159E-3 4.459E-2
2.994E-1
5.352E-1
 1 3
12 MP:0003108 short zygomatic bone 1.544E-3 4.459E-2
2.994E-1
7.135E-1
 1 4
13 MP:0010453 abnormal coronary vein morphology 1.544E-3 4.459E-2
2.994E-1
7.135E-1
 1 4
14 MP:0004116 abnormal atrioventricular bundle conduction 1.544E-3 4.459E-2
2.994E-1
7.135E-1
 1 4
15 MP:0011919 abnormal R wave 1.544E-3 4.459E-2
2.994E-1
7.135E-1
 1 4
16 MP:0001240 abnormal epidermis stratum corneum morphology 1.555E-3 4.459E-2
2.994E-1
7.184E-1
 2 169
17 MP:0010394 decreased QRS amplitude 1.930E-3 4.459E-2
2.994E-1
8.918E-1
 1 5
18 MP:0010472 abnormal ascending aorta and coronary artery attachment 1.930E-3 4.459E-2
2.994E-1
8.918E-1
 1 5
19 MP:0030315 small neurocranium 1.930E-3 4.459E-2
2.994E-1
8.918E-1
 1 5
20 MP:0006403 abnormal cochlear endolymph ionic homeostasis 1.930E-3 4.459E-2
2.994E-1
8.918E-1
 1 5
21 MP:0006110 ventricular fibrillation 2.316E-3 4.754E-2
3.192E-1
1.000E0
 1 6
22 MP:0004225 patent cardiac foramen ovale 2.316E-3 4.754E-2
3.192E-1
1.000E0
 1 6
23 MP:0013781 abnormal mammary gland luminal epithelium morphology 2.702E-3 4.754E-2
3.192E-1
1.000E0
 1 7
24 MP:0003900 shortened QT interval 2.702E-3 4.754E-2
3.192E-1
1.000E0
 1 7
25 MP:0000458 abnormal mandible morphology 2.862E-3 4.754E-2
3.192E-1
1.000E0
 2 230
26 MP:0010476 coronary fistula 3.087E-3 4.754E-2
3.192E-1
1.000E0
 1 8
27 MP:0004287 abnormal spiral limbus morphology 3.087E-3 4.754E-2
3.192E-1
1.000E0
 1 8
28 MP:0004385 interparietal bone hypoplasia 3.087E-3 4.754E-2
3.192E-1
1.000E0
 1 8
29 MP:0002911 abnormal inhibitory postsynaptic potential 3.087E-3 4.754E-2
3.192E-1
1.000E0
 1 8
30 MP:0030281 thin parietal bone 3.087E-3 4.754E-2
3.192E-1
1.000E0
 1 8
31 MP:0004562 abnormal inner hair cell synaptic ribbon morphology 3.473E-3 4.781E-2
3.210E-1
1.000E0
 1 9
32 MP:0030033 abnormal nasal bridge morphology 3.473E-3 4.781E-2
3.210E-1
1.000E0
 1 9
33 MP:0002776 Sertoli cell hyperplasia 3.473E-3 4.781E-2
3.210E-1
1.000E0
 1 9
34 MP:0000884 delaminated Purkinje cell layer 3.858E-3 4.781E-2
3.210E-1
1.000E0
 1 10
35 MP:0000126 brittle teeth 3.858E-3 4.781E-2
3.210E-1
1.000E0
 1 10
36 MP:0003838 abnormal milk ejection 4.243E-3 4.781E-2
3.210E-1
1.000E0
 1 11
37 MP:0030080 small lower incisors 4.243E-3 4.781E-2
3.210E-1
1.000E0
 1 11
38 MP:0004265 abnormal placental transport 4.243E-3 4.781E-2
3.210E-1
1.000E0
 1 11
39 MP:0002577 reduced enamel thickness 4.243E-3 4.781E-2
3.210E-1
1.000E0
 1 11
40 MP:0010205 abnormal oligodendrocyte apoptosis 4.243E-3 4.781E-2
3.210E-1
1.000E0
 1 11
41 MP:0003356 impaired luteinization 4.243E-3 4.781E-2
3.210E-1
1.000E0
 1 11
Show 36 more annotations

6: Domain [Display Chart] 5 input genes in category / 17 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS00407 CONNEXINS 1 PROSITE 3.774E-12 8.911E-12 3.065E-11 6.416E-11 4 19
2 IPR017990 Connexin CS InterPro 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
3 PS00408 CONNEXINS 2 PROSITE 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
4 IPR019570 Connexin CCC InterPro 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
5 IPR013092 Connexin N InterPro 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
6 IPR000500 Connexin InterPro 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
7 SM01089 Connexin CCC SMART 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
8 PF00029 Connexin Pfam 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
9 SM00037 CNX SMART 4.717E-12 8.911E-12 3.065E-11 8.020E-11 4 20
10 PF15847 Loricrin Pfam 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
11 IPR002260 Connexin36 InterPro 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
12 IPR002268 Connexin26 InterPro 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
13 IPR031700 Loricrin InterPro 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
14 IPR002267 Connexin32 InterPro 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
15 PF03508 Connexin43 Pfam 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
16 IPR013124 Connexin43 C InterPro 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
17 IPR002261 Connexin43 InterPro 2.669E-4 2.669E-4 9.179E-4 4.537E-3 1 1
Show 12 more annotations

7: Pathway [Display Chart] 5 input genes in category / 22 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269886 Gap junction assembly BioSystems: REACTOME 1.935E-11 2.281E-10 8.417E-10 4.257E-10 4 19
2 1269887 Transport of connexins along the secretory pathway BioSystems: REACTOME 3.110E-11 2.281E-10 8.417E-10 6.842E-10 3 3
3 1269888 Oligomerization of connexins into connexons BioSystems: REACTOME 3.110E-11 2.281E-10 8.417E-10 6.842E-10 3 3
4 1269885 Gap junction trafficking BioSystems: REACTOME 1.022E-10 5.619E-10 2.074E-9 2.247E-9 4 28
5 1269884 Gap junction trafficking and regulation BioSystems: REACTOME 1.367E-10 6.015E-10 2.220E-9 3.008E-9 4 30
6 1269889 Transport of connexons to the plasma membrane BioSystems: REACTOME 1.290E-7 4.731E-7 1.746E-6 2.839E-6 2 2
7 1269890 Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane BioSystems: REACTOME 4.016E-4 1.262E-3 4.659E-3 8.835E-3 1 1
8 83072 Gap junction BioSystems: KEGG 4.872E-4 1.340E-3 4.945E-3 1.072E-2 2 88
9 1269894 c-src mediated regulation of Cx43 function and closure of gap junctions BioSystems: REACTOME 1.204E-3 2.650E-3 9.780E-3 2.650E-2 1 3
10 1269893 Regulation of gap junction activity BioSystems: REACTOME 1.204E-3 2.650E-3 9.780E-3 2.650E-2 1 3
11 PW:0000334 connexins signaling Pathway Ontology 1.606E-3 3.211E-3 1.185E-2 3.532E-2 1 4
12 1268764 Transmission across Electrical Synapses BioSystems: REACTOME 2.007E-3 3.396E-3 1.253E-2 4.415E-2 1 5
13 1268765 Electric Transmission Across Gap Junctions BioSystems: REACTOME 2.007E-3 3.396E-3 1.253E-2 4.415E-2 1 5
14 1269892 Formation of annular gap junctions BioSystems: REACTOME 3.610E-3 5.673E-3 2.094E-2
7.942E-2
 1 9
15 1269891 Gap junction degradation BioSystems: REACTOME 4.010E-3 5.882E-3 2.171E-2
8.823E-2
 1 10
16 M11106 Inactivation of Gsk3 by AKT causes accumulation of b-catenin in Alveolar Macrophages MSigDB C2 BIOCARTA (v6.0) 1.080E-2 1.485E-2
5.480E-2
2.376E-1
 1 27
17 137919 N-cadherin signaling events BioSystems: Pathway Interaction Database 1.319E-2 1.660E-2
6.127E-2
2.901E-1
 1 33
18 169349 Validated transcriptional targets of AP1 family members Fra1 and Fra2 BioSystems: Pathway Interaction Database 1.358E-2 1.660E-2
6.127E-2
2.988E-1
 1 34
19 1457791 Formation of the cornified envelope BioSystems: REACTOME 2.820E-2 3.145E-2
1.161E-1
6.203E-1
 1 71
20 117293 Arrhythmogenic right ventricular cardiomyopathy (ARVC) BioSystems: KEGG 2.859E-2 3.145E-2
1.161E-1
6.289E-1
 1 72
Show 15 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 2659 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 17640036 Expression of connexins in embryonic mouse neocortical development. Pubmed 7.106E-15 1.890E-11 1.599E-10 1.890E-11 4 9
2 11501764 The mouse gap junction gene connexin29 is highly expressed in sciatic nerve and regulated during brain development. Pubmed 1.861E-14 2.474E-11 2.094E-10 4.949E-11 4 11
3 15466892 The novel mouse connexin39 gene is expressed in developing striated muscle fibers. Pubmed 1.342E-13 9.176E-11 7.766E-10 3.569E-10 4 17
4 14681012 An update on connexin genes and their nomenclature in mouse and man. Pubmed 1.725E-13 9.176E-11 7.766E-10 4.588E-10 4 18
5 15081111 An expression atlas of connexin genes in the mouse. Pubmed 1.725E-13 9.176E-11 7.766E-10 4.588E-10 4 18
6 15704645 Expression of connexins 26, 32 and 43 in the human colon--an immunohistochemical study. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
7 21813206 Connexin32 can restore hearing in connexin26 deficient mice. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
8 2060697 Developmental regulation of gap junction gene expression during mouse embryonic development. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
9 15013803 Loss of connexin 26 in mammary epithelium during early but not during late pregnancy results in unscheduled apoptosis and impaired development. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
10 18267319 Extracellular-loop peptide antibodies reveal a predominant hemichannel organization of connexins in polarized intestinal cells. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
11 15265710 Altered permeability and modulatory character of connexin channels during mammary gland development. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
12 10209481 Gap junctions in normal and neoplastic mammary gland. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
13 27916369 Expression of connexin 26 and connexin 43 is reduced in Hirschsprung's disease. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
14 7664837 Analysis of multiple gap junction gene products in the rodent and human mammary gland. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
15 17601673 Identification of connexin36 in gap junctions between neurons in rodent locus coeruleus. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
16 1338686 Connexin expression and gap junction communication compartments in the developing mouse limb. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
17 15334670 Are gap junction gene connexins 26, 32 and 43 of prognostic values in hepatocellular carcinoma? A prospective study. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
18 1319348 The hepatocyte-specific phenotype of murine liver cells correlates with high expression of connexin32 and connexin26 but very low expression of connexin43. Pubmed 1.077E-12 1.591E-10 1.347E-9 2.864E-9 3 3
19 1849321 Distribution of genes for gap junction membrane channel proteins on human and mouse chromosomes. Pubmed 4.308E-12 5.455E-10 4.616E-9 1.146E-8 3 4
20 1425357 Differential expression of gap junction mRNAs and proteins in the developing murine kidney and in experimentally induced nephric mesenchymes. Pubmed 4.308E-12 5.455E-10 4.616E-9 1.146E-8 3 4
21 22505190 Connexin 36 is expressed in beta and connexins 26 and 32 in acinar cells at the end of the secondary transition of mouse pancreatic development and increase during fetal and perinatal life. Pubmed 4.308E-12 5.455E-10 4.616E-9 1.146E-8 3 4
22 11980479 Connexin family members target to lipid raft domains and interact with caveolin-1. Pubmed 1.077E-11 1.302E-9 1.102E-8 2.864E-8 3 5
23 22496425 Autophagy modulates dynamics of connexins at the plasma membrane in a ubiquitin-dependent manner. Pubmed 2.154E-11 2.121E-9 1.795E-8 5.727E-8 3 6
24 1332989 Expression of connexins in the developing olfactory system of the mouse. Pubmed 2.154E-11 2.121E-9 1.795E-8 5.727E-8 3 6
25 10196667 Role of connexin (gap junction) genes in cell growth control and carcinogenesis. Pubmed 2.154E-11 2.121E-9 1.795E-8 5.727E-8 3 6
26 23261389 Linoleic acid induces opening of connexin26 hemichannels through a PI3K/Akt/Ca(2+)-dependent pathway. Pubmed 2.154E-11 2.121E-9 1.795E-8 5.727E-8 3 6
27 21807945 Peripheral lymphangiogenesis in mice depends on ectodermal connexin-26 (Gjb2). Pubmed 2.154E-11 2.121E-9 1.795E-8 5.727E-8 3 6
28 9508777 Transplacental uptake of glucose is decreased in embryonic lethal connexin26-deficient mice. Pubmed 3.769E-11 3.233E-9 2.736E-8 1.002E-7 3 7
29 10079507 Loss of alpha 1 connexin does not alter the prenatal differentiation of pancreatic beta cells and leads to the identification of another islet cell connexin. Pubmed 3.769E-11 3.233E-9 2.736E-8 1.002E-7 3 7
30 8834803 Expression of the gap junction proteins connexin31 and connexin43 correlates with communication compartments in extraembryonic tissues and in the gastrulating mouse embryo, respectively. Pubmed 3.769E-11 3.233E-9 2.736E-8 1.002E-7 3 7
31 10099690 Genetic diseases and gene knockouts reveal diverse connexin functions. Pubmed 3.769E-11 3.233E-9 2.736E-8 1.002E-7 3 7
32 9861669 Diverse functions of vertebrate gap junctions. Pubmed 6.030E-11 4.859E-9 4.112E-8 1.603E-7 3 8
33 1332196 Chromosomal assignments of mouse connexin genes, coding for gap junctional proteins, by somatic cell hybridization. Pubmed 6.030E-11 4.859E-9 4.112E-8 1.603E-7 3 8
34 20089884 Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged. Pubmed 9.045E-11 6.681E-9 5.654E-8 2.405E-7 3 9
35 14595769 Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammals. Pubmed 9.045E-11 6.681E-9 5.654E-8 2.405E-7 3 9
36 19864490 Consortin, a trans-Golgi network cargo receptor for the plasma membrane targeting and recycling of connexins. Pubmed 9.045E-11 6.681E-9 5.654E-8 2.405E-7 3 9
37 8631157 Multiple members of the connexin gene family participate in preimplantation development of the mouse. Pubmed 1.777E-10 1.243E-8 1.052E-7 4.724E-7 3 11
38 15255617 mRNA expression pattern of multiple members of connexin gene family in normal and abnormal fetal gonads in mouse. Pubmed 1.777E-10 1.243E-8 1.052E-7 4.724E-7 3 11
39 16103213 Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors. Pubmed 3.919E-10 2.672E-8 2.261E-7 1.042E-6 3 14
40 1370487 Four novel members of the connexin family of gap junction proteins. Molecular cloning, expression, and chromosome mapping. Pubmed 7.320E-10 4.866E-8 4.118E-7 1.946E-6 3 17
41 22590817 Aberrant connexin 43 and 26 expression in cervical dysplasia. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
42 19617266 Replacement of connexin 43 by connexin 32 in a knock-in mice model attenuates aortic endothelium-derived hyperpolarizing factor-mediated relaxation. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
43 8678997 Physical mapping of connexin 32 (GJB1) and 43 (GJA1) genes to bovine chromosomes Xq22 and 9q15/16 by fluorescence in situ hybridization. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
44 25206281 Connexin 32 and 43 promoter methylation in Helicobacter pylori-associated gastric tumorigenesis. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
45 10506104 Gap junction proteins connexin32 and connexin43 partially acquire growth-suppressive function in HeLa cells by deletion of their C-terminal tails. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
46 22445976 [Influence of Cx26/Cx32 gap junction channel on antineoplastic effect of etoposide in Hela cells]. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
47 15870276 Restoration of functional gap junctions through internal ribosome entry site-dependent synthesis of endogenous connexins in density-inhibited cancer cells. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
48 16407179 Mutation of a conserved threonine in the third transmembrane helix of alpha- and beta-connexins creates a dominant-negative closed gap junction channel. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
49 17904757 Connexin36 vs. connexin32, "miniature" neuronal gap junctions, and limited electrotonic coupling in rodent suprachiasmatic nucleus. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
50 12484567 Immunohistochemical and ultrastructural study of gap junction proteins connexin26 and 43 in human arachnoid villi and meningeal tumors. Pubmed 1.371E-8 3.920E-7 3.318E-6 3.646E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 97 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CNST CNST interactions 4.916E-9 4.769E-7 2.459E-6 4.769E-7 3 15
2 int:GJB1 GJB1 interactions 5.800E-6 2.813E-4 1.451E-3 5.626E-4 2 14
3 int:CAV1 CAV1 interactions 1.418E-5 4.261E-4 2.197E-3 1.376E-3 3 201
4 int:GJB2 GJB2 interactions 1.757E-5 4.261E-4 2.197E-3 1.704E-3 2 24
5 int:GJD2 GJD2 interactions 1.129E-3 1.474E-2
7.603E-2
1.095E-1
 1 4
6 int:UBQLN4 UBQLN4 interactions 1.157E-3 1.474E-2
7.603E-2
1.122E-1
 2 193
7 int:PSMD2 PSMD2 interactions 1.433E-3 1.474E-2
7.603E-2
1.390E-1
 2 215
8 int:CREB3 CREB3 interactions 1.527E-3 1.474E-2
7.603E-2
1.481E-1
 2 222
9 int:PI3 PI3 interactions 1.694E-3 1.474E-2
7.603E-2
1.643E-1
 1 6
10 int:GJA3 GJA3 interactions 1.976E-3 1.474E-2
7.603E-2
1.916E-1
 1 7
11 int:GJB6 GJB6 interactions 1.976E-3 1.474E-2
7.603E-2
1.916E-1
 1 7
12 int:GJB3 GJB3 interactions 1.976E-3 1.474E-2
7.603E-2
1.916E-1
 1 7
13 int:ZDHHC23 ZDHHC23 interactions 1.976E-3 1.474E-2
7.603E-2
1.916E-1
 1 7
14 int:GJA5 GJA5 interactions 2.258E-3 1.564E-2
8.067E-2
2.190E-1
 1 8
15 int:PRKCA PRKCA interactions 2.450E-3 1.584E-2
8.169E-2
2.376E-1
 2 282
16 int:SPRR3 SPRR3 interactions 3.103E-3 1.881E-2
9.702E-2
3.010E-1
 1 11
17 int:MUC13 MUC13 interactions 3.667E-3 2.016E-2
1.040E-1
3.557E-1
 1 13
18 int:LOR LOR interactions 3.948E-3 2.016E-2
1.040E-1
3.830E-1
 1 14
19 int:PIEZO1 PIEZO1 interactions 3.948E-3 2.016E-2
1.040E-1
3.830E-1
 1 14
20 int:ACKR3 ACKR3 interactions 4.230E-3 2.051E-2
1.058E-1
4.103E-1
 1 15
21 int:SGSM3 SGSM3 interactions 4.511E-3 2.084E-2
1.075E-1
4.376E-1
 1 16
22 int:SRC SRC interactions 4.987E-3 2.164E-2
1.116E-1
4.838E-1
 2 405
23 int:CCN3 CCN3 interactions 5.355E-3 2.164E-2
1.116E-1
5.195E-1
 1 19
24 int:SLC35E1 SLC35E1 interactions 5.355E-3 2.164E-2
1.116E-1
5.195E-1
 1 19
25 int:STS STS interactions 6.199E-3 2.405E-2
1.240E-1
6.013E-1
 1 22
26 int:SLC38A2 SLC38A2 interactions 6.480E-3 2.418E-2
1.247E-1
6.286E-1
 1 23
27 int:KCNK16 KCNK16 interactions 7.042E-3 2.530E-2
1.305E-1
6.831E-1
 1 25
28 int:B3GALNT1 B3GALNT1 interactions 7.603E-3 2.634E-2
1.358E-1
7.375E-1
 1 27
29 int:S100A1 S100A1 interactions 8.165E-3 2.729E-2
1.408E-1
7.920E-1
 1 29
30 int:CD14 CD14 interactions 9.006E-3 2.729E-2
1.408E-1
8.736E-1
 1 32
31 int:GPR52 GPR52 interactions 9.006E-3 2.729E-2
1.408E-1
8.736E-1
 1 32
32 int:TMPRSS3 TMPRSS3 interactions 9.287E-3 2.729E-2
1.408E-1
9.008E-1
 1 33
33 int:CLSPN CLSPN interactions 9.287E-3 2.729E-2
1.408E-1
9.008E-1
 1 33
34 int:STXBP2 STXBP2 interactions 9.567E-3 2.729E-2
1.408E-1
9.280E-1
 1 34
35 int:IVL IVL interactions 1.069E-2 2.867E-2
1.479E-1
1.000E0
 1 38
36 int:EVPL EVPL interactions 1.125E-2 2.867E-2
1.479E-1
1.000E0
 1 40
37 int:CSTA CSTA interactions 1.125E-2 2.867E-2
1.479E-1
1.000E0
 1 40
38 int:FSHR FSHR interactions 1.125E-2 2.867E-2
1.479E-1
1.000E0
 1 40
39 int:ZSCAN12 ZSCAN12 interactions 1.153E-2 2.867E-2
1.479E-1
1.000E0
 1 41
40 int:RAB11FIP2 RAB11FIP2 interactions 1.321E-2 3.050E-2
1.573E-1
1.000E0
 1 47
41 int:B4GAT1 B4GAT1 interactions 1.321E-2 3.050E-2
1.573E-1
1.000E0
 1 47
42 int:TSPAN17 TSPAN17 interactions 1.321E-2 3.050E-2
1.573E-1
1.000E0
 1 47
43 int:FBXO2 FBXO2 interactions 1.376E-2 3.096E-2
1.597E-1
1.000E0
 1 49
44 int:NBR1 NBR1 interactions 1.404E-2 3.096E-2
1.597E-1
1.000E0
 1 50
45 int:DPEP1 DPEP1 interactions 1.544E-2 3.315E-2
1.709E-1
1.000E0
 1 55
46 int:NT5E NT5E interactions 1.572E-2 3.315E-2
1.709E-1
1.000E0
 1 56
47 int:GJA1 GJA1 interactions 1.655E-2 3.345E-2
1.725E-1
1.000E0
 1 59
48 int:ANTXR1 ANTXR1 interactions 1.655E-2 3.345E-2
1.725E-1
1.000E0
 1 59
49 int:OCLN OCLN interactions 1.767E-2 3.373E-2
1.739E-1
1.000E0
 1 63
50 int:MAPK7 MAPK7 interactions 1.823E-2 3.373E-2
1.739E-1
1.000E0
 1 65
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 6q21-q23.2 6q21-q23.2 1.443E-4 7.213E-4 1.647E-3 7.213E-4 1 1
2 13q11-q12 13q11-q12 5.769E-4 1.442E-3 3.293E-3 2.885E-3 1 4
3 Xq13.1 Xq13.1 7.192E-3 9.349E-3 2.135E-2 3.596E-2 1 50
4 15q14 15q14 7.479E-3 9.349E-3 2.135E-2 3.740E-2 1 52
5 1q21 1q21 1.334E-2 1.334E-2 3.047E-2
6.672E-2
 1 93

11: Transcription Factor Binding Site [Display Chart] 4 input genes in category / 31 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$P300 01 V$P300 01 2.269E-3 3.518E-2
1.417E-1
7.035E-2
 2 193
2 V$AP1 Q4 01 V$AP1 Q4 01 2.913E-3 3.518E-2
1.417E-1
9.031E-2
 2 219
3 V$AP1 C V$AP1 C 3.404E-3 3.518E-2
1.417E-1
1.055E-1
 2 237

12: Gene Family [Display Chart] 5 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 314 Gap junction proteins genenames.org 8.007E-12 2.402E-11 4.404E-11 2.402E-11 4 22
2 1352 Cornified envelope precursor family genenames.org 5.496E-4 8.244E-4 1.511E-3 1.649E-3 1 2
3 1152 Deafness associated genes genenames.org 3.789E-2 3.789E-2
6.947E-2
1.137E-1
 1 140

13: Coexpression [Display Chart] 5 input genes in category / 553 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16138077-Table2 Mouse Liver Gresh05 06genes GeneSigDB 5.602E-7 3.098E-4 2.136E-3 3.098E-4 2 6
2 18356575-Table1a Human MesenchymalStemCells Rider08 22genes GeneSigDB 6.380E-6 1.764E-3 1.216E-2 3.528E-3 2 19
3 19584277-Table2 Human Breast Marella09 30genes GeneSigDB 1.409E-5 2.597E-3 1.791E-2 7.792E-3 2 28
4 19305503-TableS1 Rat Brain Greco09 425genes GeneSigDB 4.529E-5 6.262E-3 4.316E-2 2.505E-2 3 387
5 16488994-SuppTable1b Mouse Lung Lu06 856genes Array MEO430Av2 GeneSigDB 6.775E-5 6.500E-3 4.481E-2 3.747E-2 3 443
6 16488994-SuppTable1a Mouse Lung Lu06 856genes Array MG U74Av2 GeneSigDB 7.052E-5 6.500E-3 4.481E-2 3.900E-2 3 449
7 19286929-SuppTable2h Mouse Lung Rangasamy09 98genes GeneSigDB 1.324E-4 1.004E-2
6.920E-2
7.323E-2
 2 85
8 15892885-tableS1c Human Prostate Chandran05 101genes Tumor v AdjNormal GeneSigDB 1.452E-4 1.004E-2
6.920E-2
8.030E-2
 2 89
9 15532095-Table3 Human Prostate Kristiansen05 188genes GeneSigDB 2.597E-4 1.596E-2
1.100E-1
1.436E-1
 2 119
10 M433 Genes up-regulated in neutrophils isolated from: healthy versus patients with peridontitis. MSigDB C7: Immunologic Signatures (v6.0) 3.194E-4 1.757E-2
1.211E-1
1.766E-1
 2 132
11 M8901 Down-regulated genes from the 324 genes identified by two analytical methods as changed in the mammary tumors induced by transgenic expression of ERBB2 [GeneID=2064]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.067E-4 1.757E-2
1.211E-1
2.249E-1
 2 149
12 M9520 Genes up-regulated in CD8 T effectors at acute infection with LCMV-Armstrong: day 6 versus day 15. MSigDB C7: Immunologic Signatures (v6.0) 7.021E-4 1.757E-2
1.211E-1
3.883E-1
 2 196
13 M7121 Genes down-regulated in peripheral blood monocytes (PMBC):healthy versus Gram positive sepsis. MSigDB C7: Immunologic Signatures (v6.0) 7.092E-4 1.757E-2
1.211E-1
3.922E-1
 2 197
14 M8431 Genes down-regulated in CD8 T cells: central memory versus naïve. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 1.757E-2
1.211E-1
4.002E-1
 2 199
15 M3627 Genes up-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after treatment with trichostatin A (TSA) [PubChem=5562]. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 1.757E-2
1.211E-1
4.002E-1
 2 199
16 M6982 Genes up-regulated in macrophages in response to LPS: naïve versus tolerant. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 1.757E-2
1.211E-1
4.002E-1
 2 199
17 M6990 Genes up-regulated in allogeneic T cells after stimulation with dendritic cells from: liver versus mesenteric lymph nodes (mLN). MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
18 M5713 Genes up-regulated in comparison of Ctrlrv versus Foxp3rv (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
19 M9757 Genes down-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus Ly6c int CXCR5+ [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
20 M3623 Genes up-regulated in comparison of unstimulated CD8 T cells at 24 h versus CD8 T cells at 24 h after stimulation with antigen-B7-1. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
21 M3315 Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes versus CD8 thymocytes. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
22 M3640 Genes down-regulated in comparison of unstimulated CD8 T cells at 72 h versus CD8 T cells at 72 h after stimulation with IL12. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
23 M9692 Genes down-regulated in CD4 [GeneID=920] T helper cells Th0: 10h versus 60h. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 1.757E-2
1.211E-1
4.042E-1
 2 200
24 M1376 Genes down-regulated in MMH-RT cells (hepatocytes displaying an invasive, metastatic phenotype) during epithelial to mesenchymal transition (EMT). MSigDB C2: CGP Curated Gene Sets (v6.0) 7.751E-4 1.786E-2
1.231E-1
4.286E-1
 2 206
25 M10702 Genes down-regulated in metastases from malignant melanoma compared to the primary tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.211E-3 2.655E-2
1.830E-1
6.700E-1
 2 258
26 M19256 Genes up-regulated in pleura relapse of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.296E-3 2.655E-2
1.830E-1
7.167E-1
 1 6
27 M12533 Genes down-regulated in prostate tumor vs normal tissue samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.296E-3 2.655E-2
1.830E-1
7.167E-1
 1 6
28 15064725-table2 Human Lung Tomida04 12genes GeneSigDB 1.944E-3 3.714E-2
2.560E-1
1.000E0
 1 9
29 19061838-TableS13 Mouse Viral Cairo08 620genes GeneSigDB 1.948E-3 3.714E-2
2.560E-1
1.000E0
 2 328
30 M2009 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.103E-3 3.877E-2
2.672E-1
1.000E0
 2 341
31 M1949 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) and trimethylation mark at K27 (H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.202E-3 3.927E-2
2.707E-1
1.000E0
 2 349
32 18435859-ShorterGeneList Mouse Breast Piechocki08 558genes GeneSigDB 2.550E-3 4.407E-2
3.038E-1
1.000E0
 2 376
33 19074870-SuppTable4a Human StemCell Harris08 490genes GeneSigDB 2.852E-3 4.768E-2
3.287E-1
1.000E0
 2 398
34 15901920-Table3 Rat Testicular Naciff05 23genes GeneSigDB 3.022E-3 4.768E-2
3.287E-1
1.000E0
 1 14
35 M1482 Genes down-regulated in pancreatic cells from mice with double knockout of E2F1 [GeneID=1869] and E2F2 [GeneID=1870] compared to wild type. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.453E-3 4.768E-2
3.287E-1
1.000E0
 1 16
36 16948840-Table2 Human Viral Keating06 28genes DownRegulated GeneSigDB 3.669E-3 4.768E-2
3.287E-1
1.000E0
 1 17
37 18356575-Table1b Human MesenchymalStemCells Rider08 21genes GeneSigDB 3.884E-3 4.768E-2
3.287E-1
1.000E0
 1 18
38 M2053 Top genes associated with chemosensitivity to vinblastine [PubChem=13342] across 85 tumor xenografts. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.884E-3 4.768E-2
3.287E-1
1.000E0
 1 18
39 15231654-Table3 Human Kidney Myers04 21genes GeneSigDB 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
40 M2935 The cyclin D1 signature: genes whose expression correlated with the levels of CCND1 [GeneID=595]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
41 M4435 Genes down-regulated in the uteri of ovariectomized mice 6 h after progesterone [PubChem=5994] injection: HOXA10 [GeneID=3206] knockout vs wild type animals. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
42 17638852-Table3 Human Lymphoma Shin07 20genes GeneSigDB 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
43 15520187-Table2b Human Bladder Nicholson04 20genes Loss GeneSigDB 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
44 M1821 Genes important for embryonic germ cell, based on mouse models with female fertility defects. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
45 15073113-Table2 Human Testicular Sugimura04 30genes EmbryonalCarcinoma GeneSigDB 4.100E-3 4.768E-2
3.287E-1
1.000E0
 1 19
46 M19097 Genes up-regulated in the Kras2LA mouse lung cancer model with mutated KRAS [GeneID=3845]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.307E-3 4.768E-2
3.287E-1
1.000E0
 2 491
47 M9611 Genes up-regulated in derivatives of MCF-7aro cells (breast cancer) that developed resistance to tamoxifen [PubChem=5376] or inhibitors of aromatase (CYP19A1) [GeneID=1588]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.315E-3 4.768E-2
3.287E-1
1.000E0
 1 20
48 15173083-Table2 Human Brain Levy04 32genes GeneSigDB 4.530E-3 4.768E-2
3.287E-1
1.000E0
 1 21
49 19347029-Table3 Human Prostate Zhou09 23genes GeneSigDB 4.530E-3 4.768E-2
3.287E-1
1.000E0
 1 21
50 15120971-Table2 Mouse Leukemia Faiola03 29genes GeneSigDB 4.530E-3 4.768E-2
3.287E-1
1.000E0
 1 21
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 759 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn Thalamus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn Thalamus Top 200 Genes BrainMap 3.660E-5 2.739E-2
1.975E-1
 2.778E-2 3 340
2 Facebase ST1 Univ 500 UniversalReference WholeMouseP1 top-relative-expression-ranked 500 FaceBase_ST1 7.218E-5 2.739E-2
1.975E-1
5.479E-2
 3 427
3 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma /Conventional Leiomyosarcoma/3/4 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma /Conventional Leiomyosarcoma/3/4 TCGA-Bone and Soft Tissue 4.385E-4 3.662E-2
2.641E-1
3.328E-1
 2 146
4 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligoastrocytoma/2/3 Sample Type by Project: Shred 1/TCGA-Brain/Low Grade Glioma/Oligoastrocytoma/2/3 TCGA-Brain 4.876E-4 3.662E-2
2.641E-1
3.701E-1
 2 154
5 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr epithel 200 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr epithel emap-30875 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 5.868E-4 3.662E-2
2.641E-1
4.454E-1
 2 169
6 Sample Type by Project: Shred 1/TCGA-Uvea/Uveal Melanoma/Epithelioid Cell/3/6 Sample Type by Project: Shred 1/TCGA-Uvea/Uveal Melanoma/Epithelioid Cell/3/6 TCGA-Uvea 6.434E-4 3.662E-2
2.641E-1
4.883E-1
 2 177
7 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Pancreas/pancreatic ductal cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Pancreas/pancreatic ductal cell Tabula Muris Consortium 7.177E-4 3.662E-2
2.641E-1
5.447E-1
 2 187
8 BrainMap BrainAtlas - Human / Mouse Linnarsson Leptomeningeal Leptomeningeal Top 200 BrainMap BrainAtlas - Human / Mouse Linnarsson Leptomeningeal Leptomeningeal Top 200 BrainMap 7.485E-4 3.662E-2
2.641E-1
5.681E-1
 2 191
9 BrainMap BrainAtlas - Human / Mouse Linnarsson Leptomeningeal Leptomeningeal Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Leptomeningeal Leptomeningeal Overall Top 200 Genes BrainMap 7.485E-4 3.662E-2
2.641E-1
5.681E-1
 2 191
10 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Endothelial Tip BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Endothelial Tip BrainMap 7.642E-4 3.662E-2
2.641E-1
5.800E-1
 2 193
11 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. Endothelial Tip. Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. Endothelial Tip. Overall Top 200 Genes BrainMap 7.721E-4 3.662E-2
2.641E-1
5.860E-1
 2 194
12 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip Endothelial Tip Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip Endothelial Tip Overall Top 200 Genes BrainMap 7.721E-4 3.662E-2
2.641E-1
5.860E-1
 2 194
13 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Overall Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Overall Top 200 Genes 7.721E-4 3.662E-2
2.641E-1
5.860E-1
 2 194
14 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip Endothelial Tip Top 200 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip Endothelial Tip Top 200 BrainMap 7.721E-4 3.662E-2
2.641E-1
5.860E-1
 2 194
15 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Overall Top 200 Genes BrainMap 7.721E-4 3.662E-2
2.641E-1
5.860E-1
 2 194
16 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. Endothelial Tip. Top 200 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. Endothelial Tip. Top 200 BrainMap 7.721E-4 3.662E-2
2.641E-1
5.860E-1
 2 194
17 Facebase ST1 Univ 250 UniversalReference WholeMouseP1 top-relative-expression-ranked 250 FaceBase_ST1 8.698E-4 3.727E-2
2.687E-1
6.602E-1
 2 206
18 Facebase ST1 Univ 500 4 UniversalReference WholeMouseP1 top-relative-expression-ranked 500 4 FaceBase_ST1 9.469E-4 3.727E-2
2.687E-1
7.187E-1
 2 215
19 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn SubstantiaNigra Top 200 Genes BrainMap 1.520E-3 3.727E-2
2.687E-1
1.000E0
 2 273
20 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Entopeduncular Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Entopeduncular Top 200 Genes BrainMap 1.587E-3 3.727E-2
2.687E-1
1.000E0
 2 279
21 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Inmt Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Inmt Top 200 Genes 1.725E-3 3.727E-2
2.687E-1
1.000E0
 2 291
22 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Inmt Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Inmt Top 200 Genes BrainMap 1.725E-3 3.727E-2
2.687E-1
1.000E0
 2 291
23 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Ifitm1 Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Ifitm1 Top 200 Genes 1.832E-3 3.727E-2
2.687E-1
1.000E0
 2 300
24 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Ifitm1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Ifitm1 Top 200 Genes BrainMap 1.832E-3 3.727E-2
2.687E-1
1.000E0
 2 300
25 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn Cerebellum Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn Cerebellum Top 200 Genes BrainMap 1.868E-3 3.727E-2
2.687E-1
1.000E0
 2 303
26 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Nnat Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Nnat Top 200 Genes BrainMap 1.954E-3 3.727E-2
2.687E-1
1.000E0
 2 310
27 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Nnat Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Nnat Top 200 Genes 1.954E-3 3.727E-2
2.687E-1
1.000E0
 2 310
28 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf GlobusPallidus Top 200 Genes BrainMap 1.992E-3 3.727E-2
2.687E-1
1.000E0
 2 313
29 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn Hippocampus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn Hippocampus Top 200 Genes BrainMap 2.004E-3 3.727E-2
2.687E-1
1.000E0
 2 314
30 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Cerebellum/Cerebellum/Oligodendrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Cerebellum/Cerebellum/Oligodendrocyte BrainMap 2.060E-3 3.727E-2
2.687E-1
1.000E0
 1 9
31 BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte. .Trf Oligodendrocyte. .Trf Subtype Oligodendrocyte. .Trf.Ndrg2 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte. .Trf Oligodendrocyte. .Trf Subtype Oligodendrocyte. .Trf.Ndrg2 Top 200 Genes BrainMap 2.119E-3 3.727E-2
2.687E-1
1.000E0
 2 323
32 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Coch Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Coch Top 200 Genes 2.211E-3 3.727E-2
2.687E-1
1.000E0
 2 330
33 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Coch Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Coch Top 200 Genes BrainMap 2.224E-3 3.727E-2
2.687E-1
1.000E0
 2 331
34 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/PosteriorCortex/PosteriorCortex/Endothelial Tip BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/PosteriorCortex/PosteriorCortex/Endothelial Tip BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
35 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/SubstantiaNigra/SubstantiaNigra/Oligodendrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/SubstantiaNigra/SubstantiaNigra/Oligodendrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
36 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Striatum/Striatum/Oligodendrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Striatum/Striatum/Oligodendrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
37 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/SubstantiaNigra/SubstantiaNigra/Endothelial Tip BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/SubstantiaNigra/SubstantiaNigra/Endothelial Tip BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
38 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/GlobusPallidus/GlobusPallidus/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/GlobusPallidus/GlobusPallidus/Astrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
39 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Striatum/Striatum/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Striatum/Striatum/Astrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
40 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/GlobusPallidus/GlobusPallidus/Oligodendrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/GlobusPallidus/GlobusPallidus/Oligodendrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
41 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/PosteriorCortex/PosteriorCortex/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/PosteriorCortex/PosteriorCortex/Astrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
42 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex/FrontalCortex/Endothelial Tip BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex/FrontalCortex/Endothelial Tip BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
43 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex/FrontalCortex/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/FrontalCortex/FrontalCortex/Astrocyte BrainMap 2.289E-3 3.727E-2
2.687E-1
1.000E0
 1 10
44 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Mgp Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Mgp Top 200 Genes 2.291E-3 3.727E-2
2.687E-1
1.000E0
 2 336
45 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Mgp Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Mgp Top 200 Genes BrainMap 2.291E-3 3.727E-2
2.687E-1
1.000E0
 2 336
46 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Dcn Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn.Dcn Top 200 Genes BrainMap 2.386E-3 3.727E-2
2.687E-1
1.000E0
 2 343
47 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Dcn Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Endothelial Tip Subtype Dcn.Dcn Top 200 Genes 2.386E-3 3.727E-2
2.687E-1
1.000E0
 2 343
48 BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Endothelial Tip. .Dcn Endothelial Tip. .Dcn Subtype Endothelial Tip. .Dcn GlobusPallidus Top 200 Genes BrainMap 2.427E-3 3.727E-2
2.687E-1
1.000E0
 2 346
49 BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll subAstrocyte.subGroup2 subAstrocyte.subGroup2 Subtype subAstrocyte.subGroup2 GlobusPallidus Top 200 Genes BrainMap 2.441E-3 3.727E-2
2.687E-1
1.000E0
 2 347
50 gudmap dev gonad e11.5 F GonadVasMes Flk k4 100 dev gonad e11.5 F GonadVasMes Flk k-means-cluster#4 top-relative-expression-ranked 100 Gudmap Mouse ST 1.0 2.517E-3 3.727E-2
2.687E-1
1.000E0
 1 11
Show 45 more annotations

15: Computational [Display Chart] 4 input genes in category / 73 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M10197 MODULE 92 Secreted signaling molecules. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.269E-5 9.262E-4 4.515E-3 9.262E-4 3 149
2 M5770 MODULE 63 Porins / transporters. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.608E-5 1.317E-3 6.419E-3 2.634E-3 3 211

16: MicroRNA [Display Chart] 5 input genes in category / 184 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-1911:mirSVR highEffct hsa-miR-1911:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.637E-4 1.336E-2
7.745E-2
 3.013E-2 2 294
2 hsa-miR-6817-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.975E-4 1.336E-2
7.745E-2
 3.635E-2 2 323
3 hsa-miR-7110-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.305E-4 1.336E-2
7.745E-2
 4.241E-2 2 349
4 hsa-miR-6873-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.905E-4 1.336E-2
7.745E-2
5.346E-2
 2 392
5 hsa-miR-1295a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.075E-3 2.717E-2
1.575E-1
3.817E-1
 1 30
6 hsa-miR-4521:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.282E-3 2.717E-2
1.575E-1
4.199E-1
 1 33
7 hsa-miR-3142:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.696E-3 2.717E-2
1.575E-1
4.961E-1
 1 39
8 hsa-miR-1245b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.766E-3 2.717E-2
1.575E-1
5.089E-1
 1 40
9 hsa-miR-5704:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.180E-3 2.717E-2
1.575E-1
5.851E-1
 1 46
10 hsa-miR-1298-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.732E-3 2.717E-2
1.575E-1
6.867E-1
 1 54
11 hsa-miR-4686:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.732E-3 2.717E-2
1.575E-1
6.867E-1
 1 54
12 hsa-miR-3137:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.801E-3 2.717E-2
1.575E-1
6.994E-1
 1 55
13 hsa-miR-6894-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.353E-3 2.717E-2
1.575E-1
8.009E-1
 1 63
14 hsa-miR-651-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.491E-3 2.717E-2
1.575E-1
8.263E-1
 1 65
15 hsa-miR-3184-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.629E-3 2.717E-2
1.575E-1
8.517E-1
 1 67
16 hsa-miR-101-5p:Functional MTI Functional MTI miRTarbase 4.698E-3 2.717E-2
1.575E-1
8.644E-1
 1 68
17 hsa-miR-6802-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.974E-3 2.717E-2
1.575E-1
9.151E-1
 1 72
18 hsa-miR-6813-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 2.717E-2
1.575E-1
9.405E-1
 1 74
19 hsa-miR-4763-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 2.717E-2
1.575E-1
9.405E-1
 1 74
20 hsa-miR-502-5p:Functional MTI Functional MTI miRTarbase 5.111E-3 2.717E-2
1.575E-1
9.405E-1
 1 74
21 hsa-miR-648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 2.717E-2
1.575E-1
9.405E-1
 1 74
22 hsa-miR-4283:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.387E-3 2.717E-2
1.575E-1
9.912E-1
 1 78
23 hsa-miR-6085:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.387E-3 2.717E-2
1.575E-1
9.912E-1
 1 78
24 hsa-miR-103a-2-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.594E-3 2.717E-2
1.575E-1
1.000E0
 1 81
25 hsa-miR-382-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.594E-3 2.717E-2
1.575E-1
1.000E0
 1 81
26 hsa-miR-34a-3p:Functional MTI Functional MTI miRTarbase 5.594E-3 2.717E-2
1.575E-1
1.000E0
 1 81
27 hsa-miR-4511:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.801E-3 2.717E-2
1.575E-1
1.000E0
 1 84
28 hsa-miR-6784-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.869E-3 2.717E-2
1.575E-1
1.000E0
 1 85
29 hsa-miR-1273a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.938E-3 2.717E-2
1.575E-1
1.000E0
 1 86
30 hsa-miR-6862-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.007E-3 2.717E-2
1.575E-1
1.000E0
 1 87
31 hsa-miR-1281:mirSVR highEffct hsa-miR-1281:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.352E-3 2.717E-2
1.575E-1
1.000E0
 1 92
32 hsa-miR-4266:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.489E-3 2.717E-2
1.575E-1
1.000E0
 1 94
33 hsa-miR-20b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.558E-3 2.717E-2
1.575E-1
1.000E0
 1 95
34 hsa-miR-1825:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.833E-3 2.717E-2
1.575E-1
1.000E0
 1 99
35 hsa-miR-636:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.971E-3 2.717E-2
1.575E-1
1.000E0
 1 101
36 hsa-miR-595:Functional MTI Functional MTI miRTarbase 6.971E-3 2.717E-2
1.575E-1
1.000E0
 1 101
37 hsa-miR-1286:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.109E-3 2.717E-2
1.575E-1
1.000E0
 1 103
38 hsa-miR-139-3p:mirSVR highEffct hsa-miR-139-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 7.109E-3 2.717E-2
1.575E-1
1.000E0
 1 103
39 hsa-miR-3691-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.246E-3 2.717E-2
1.575E-1
1.000E0
 1 105
40 GCTTGAA,MIR-498:MSigDB GCTTGAA,MIR-498:MSigDB MSigDB 7.315E-3 2.717E-2
1.575E-1
1.000E0
 1 106
41 hsa-miR-6811-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.315E-3 2.717E-2
1.575E-1
1.000E0
 1 106
42 hsa-miR-6511b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.384E-3 2.717E-2
1.575E-1
1.000E0
 1 107
43 hsa-miR-4786-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.659E-3 2.717E-2
1.575E-1
1.000E0
 1 111
44 hsa-miR-548o-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.141E-3 2.717E-2
1.575E-1
1.000E0
 1 118
45 hsa-miR-4309:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.209E-3 2.717E-2
1.575E-1
1.000E0
 1 119
46 hsa-miR-1323:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.278E-3 2.717E-2
1.575E-1
1.000E0
 1 120
47 hsa-miR-3198:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.347E-3 2.717E-2
1.575E-1
1.000E0
 1 121
48 hsa-miR-3910:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.347E-3 2.717E-2
1.575E-1
1.000E0
 1 121
49 hsa-miR-206:Functional MTI Functional MTI miRTarbase 8.416E-3 2.717E-2
1.575E-1
1.000E0
 1 122
50 hsa-miR-6837-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.553E-3 2.717E-2
1.575E-1
1.000E0
 1 124
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 675 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000008129 heptanol Stitch 4.930E-11 1.699E-8 1.205E-7 3.327E-8 4 42
2 CID000041223 N-ethyl-N-(4-hydroxybutyl)nitrosamine Stitch 5.035E-11 1.699E-8 1.205E-7 3.399E-8 3 5
3 CID000002561 AC1N7HR9 Stitch 9.329E-11 2.011E-8 1.427E-7 6.297E-8 4 49
4 CID000070815 C-X-S Stitch 1.192E-10 2.011E-8 1.427E-7 8.045E-8 4 52
5 CID000000957 octanol Stitch 3.171E-10 4.281E-8 3.037E-7 2.141E-7 4 66
6 CID000003230 18b-glycyrrhetic acid Stitch 8.081E-10 9.092E-8 6.448E-7 5.455E-7 4 83
7 CID006335488 Lucifer yellow Stitch 2.829E-9 2.728E-7 1.935E-6 1.909E-6 4 113
8 CID000014886 Cascade Blue Stitch 6.690E-9 5.644E-7 4.003E-6 4.515E-6 3 21
9 ctd:C010723 N-ethyl-N-(4-hydroxybutyl)nitrosamine CTD 3.834E-8 2.875E-6 2.039E-5 2.588E-5 2 2
10 CID000001930 elaidamide Stitch 9.250E-8 6.244E-6 4.428E-5 6.244E-5 3 49
11 CID003002894 AC1MHEDP Stitch 1.805E-7 1.108E-5 7.858E-5 1.219E-4 3 61
12 ctd:C013883 chrysarobin CTD 3.833E-7 2.156E-5 1.529E-4 2.587E-4 2 5
13 ctd:C420218 acetyl-leucyl-glutamyl-histidyl-aspartal CTD 5.749E-7 2.985E-5 2.117E-4 3.880E-4 2 6
14 CID000008370 hexachlorobenzene Stitch 8.847E-7 4.159E-5 2.950E-4 5.972E-4 3 103
15 CID000003371 flufenamic acid Stitch 1.021E-6 4.159E-5 2.950E-4 6.892E-4 3 108
16 ctd:C001042 2',3-dimethyl-4-aminobiphenyl CTD 1.073E-6 4.159E-5 2.950E-4 7.242E-4 2 8
17 ctd:C029407 oleylamide CTD 1.073E-6 4.159E-5 2.950E-4 7.242E-4 2 8
18 CID000023961 thulium Stitch 1.109E-6 4.159E-5 2.950E-4 7.486E-4 3 111
19 CID000166548 Anidulafungin Stitch 3.154E-6 1.120E-4 7.945E-4 2.129E-3 3 157
20 ctd:C099158 acetyl-aspartyl-glutamyl-valyl-aspartal CTD 3.485E-6 1.120E-4 7.945E-4 2.352E-3 2 14
21 ctd:D002697 Chloral Hydrate CTD 3.485E-6 1.120E-4 7.945E-4 2.352E-3 2 14
22 ctd:C025164 fucoxanthin CTD 7.273E-6 2.231E-4 1.583E-3 4.909E-3 2 20
23 ctd:D001585 Benzoyl Peroxide CTD 1.243E-5 3.649E-4 2.588E-3 8.393E-3 2 26
24 CID000444581 AC1L9GJY Stitch 1.343E-5 3.776E-4 2.678E-3 9.063E-3 2 27
25 CID000003752 irsogladine Stitch 1.446E-5 3.904E-4 2.769E-3 9.759E-3 2 28
26 CID000093368 LYCH Stitch 1.778E-5 4.616E-4 3.274E-3 1.200E-2 2 31
27 ctd:D005038 Ethylnitrosourea CTD 2.071E-5 5.177E-4 3.672E-3 1.398E-2 3 294
28 ctd:D003633 Dichlorodiphenyl Dichloroethylene CTD 2.266E-5 5.433E-4 3.853E-3 1.530E-2 3 303
29 ctd:D003634 DDT CTD 2.334E-5 5.433E-4 3.853E-3 1.576E-2 3 306
30 CID000329293 NSC311040 Stitch 2.545E-5 5.542E-4 3.931E-3 1.718E-2 2 37
31 CID000068111 chrysarobin Stitch 2.545E-5 5.542E-4 3.931E-3 1.718E-2 2 37
32 CID000123885 CGP55845 Stitch 3.133E-5 6.484E-4 4.599E-3 2.115E-2 2 41
33 ctd:D004121 Dimethyl Sulfoxide CTD 3.170E-5 6.484E-4 4.599E-3 2.140E-2 3 339
34 ctd:C093642 SB 203580 CTD 4.742E-5 9.415E-4 6.678E-3 3.201E-2 3 388
35 ctd:C093973 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one CTD 5.271E-5 1.017E-3 7.210E-3 3.558E-2 3 402
36 ctd:D015073 2-Acetylaminofluorene CTD 5.713E-5 1.071E-3 7.597E-3 3.856E-2 3 413
37 ctd:C038983 1,3-dimethylthiourea CTD 6.306E-5 1.120E-3 7.945E-3 4.257E-2 2 58
38 CID000447960 CK 6 Stitch 6.306E-5 1.120E-3 7.945E-3 4.257E-2 2 58
39 CID000196705 alpha-CaM Stitch 7.212E-5 1.248E-3 8.853E-3 4.868E-2 2 62
40 CID000057056 AC1L1M7Y Stitch 8.941E-5 1.509E-3 1.070E-2
6.035E-2
 2 69
41 CID000024524 Fluor Stitch 1.057E-4 1.740E-3 1.234E-2
7.135E-2
 2 75
42 CID000003495 glycrrhizin Stitch 1.391E-4 2.235E-3 1.586E-2
9.389E-2
 2 86
43 ctd:D012967 Sodium Dodecyl Sulfate CTD 2.154E-4 3.086E-3 2.189E-2
1.454E-1
 2 107
44 ctd:C023845 N-ethyl-N-hydroxyethylnitrosamine CTD 2.189E-4 3.086E-3 2.189E-2
1.478E-1
 1 1
45 ctd:C476033 Maharishi Amrit Kalash CTD 2.189E-4 3.086E-3 2.189E-2
1.478E-1
 1 1
46 CID000003863 N6-(1-iminoethyl)-L-lysine Stitch 2.189E-4 3.086E-3 2.189E-2
1.478E-1
 1 1
47 ctd:C542870 onabotulinumtoxinA CTD 2.189E-4 3.086E-3 2.189E-2
1.478E-1
 1 1
48 ctd:D006534 Heptachlor Epoxide CTD 2.195E-4 3.086E-3 2.189E-2
1.481E-1
 2 108
49 CID000002521 AC1L3C9O Stitch 2.277E-4 3.136E-3 2.224E-2
1.537E-1
 2 110
50 ctd:D002738 Chloroquine CTD 2.360E-4 3.186E-3 2.260E-2
1.593E-1
 2 112
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 631 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0022579 Keratoderma DisGeNET BeFree 6.409E-9 4.044E-6 2.841E-5 4.044E-6 3 15
2 C0265964 Mutilating keratoderma DisGeNET Curated 2.285E-7 4.805E-5 3.376E-4 1.442E-4 2 3
3 C1866032 Honeycomb palmoplantar keratoderma DisGeNET Curated 2.285E-7 4.805E-5 3.376E-4 1.442E-4 2 3
4 C0014173 Endometrial Hyperplasia DisGeNET Curated 8.714E-7 1.194E-4 8.386E-4 5.499E-4 3 73
5 C0022596 Palmoplantar Keratosis DisGeNET Curated 9.459E-7 1.194E-4 8.386E-4 5.969E-4 3 75
6 C3665333 Keratitis-Ichthyosis-Deafness Syndrome DisGeNET Curated 1.142E-6 1.201E-4 8.437E-4 7.206E-4 2 6
7 C0016382 Flushing DisGeNET Curated 1.432E-6 1.261E-4 8.858E-4 9.037E-4 3 86
8 C0334166 Pseudoainhum DisGeNET Curated 1.598E-6 1.261E-4 8.858E-4 1.009E-3 2 7
9 C0041834 Erythema DisGeNET Curated 1.935E-6 1.345E-4 9.447E-4 1.221E-3 3 95
10 C0265961 Erythrokeratodermia variabilis DisGeNET Curated 2.131E-6 1.345E-4 9.447E-4 1.345E-3 2 8
11 C0221166 Paraparesis DisGeNET Curated 2.740E-6 1.458E-4 1.024E-3 1.729E-3 2 9
12 C0268621 Hepatic methionine adenosyltransferase deficiency DisGeNET Curated 2.772E-6 1.458E-4 1.024E-3 1.749E-3 3 107
13 C1969913 Hyperkeratosis, generalized DisGeNET Curated 6.921E-6 3.359E-4 2.360E-3 4.367E-3 2 14
14 C1846647 DEAFNESS, AUTOSOMAL RECESSIVE (disorder) DisGeNET BeFree 1.034E-5 4.317E-4 3.033E-3 6.524E-3 2 17
15 C0948163 Leukoaraiosis DisGeNET Curated 1.163E-5 4.317E-4 3.033E-3 7.339E-3 2 18
16 C4020851 Cortical white matter abnormalities seen on MRI DisGeNET Curated 1.163E-5 4.317E-4 3.033E-3 7.339E-3 2 18
17 C3551426 Dystrophic fingernails DisGeNET Curated 1.163E-5 4.317E-4 3.033E-3 7.339E-3 2 18
18 C0037286 Skin Neoplasms DisGeNET Curated 3.139E-5 1.100E-3 7.730E-3 1.980E-2 3 240
19 C1843300 Sparse eyelashes DisGeNET Curated 3.764E-5 1.250E-3 8.782E-3 2.375E-2 2 32
20 C0037277 Skin Diseases, Genetic DisGeNET BeFree 6.843E-5 2.056E-3 1.445E-2 4.318E-2 2 43
21 C0423867 Fine hair DisGeNET Curated 6.843E-5 2.056E-3 1.445E-2 4.318E-2 2 43
22 C0020758 Congenital ichthyosis DisGeNET Curated 8.543E-5 2.291E-3 1.609E-2
5.391E-2
 2 48
23 C0037268 Skin Abnormalities DisGeNET Curated 1.043E-4 2.291E-3 1.609E-2
6.581E-2
 2 53
24 C1834405 Nail dysplasia DisGeNET Curated 1.165E-4 2.291E-3 1.609E-2
7.352E-2
 2 56
25 C0750974 Brain Tumor, Primary DisGeNET BeFree 1.207E-4 2.291E-3 1.609E-2
7.619E-2
 2 57
26 C0037274 Dermatologic disorders DisGeNET Curated 1.365E-4 2.291E-3 1.609E-2
8.614E-2
 3 393
27 C1837770 Sparse hair DisGeNET Curated 1.384E-4 2.291E-3 1.609E-2
8.731E-2
 2 61
28 C1860844 Thin, sparse hair DisGeNET Curated 1.384E-4 2.291E-3 1.609E-2
8.731E-2
 2 61
29 C0015230 Exanthema DisGeNET Curated 1.675E-4 2.291E-3 1.609E-2
1.057E-1
 3 421
30 C0020757 Ichthyoses DisGeNET Curated 1.772E-4 2.291E-3 1.609E-2
1.118E-1
 2 69
31 C3711374 Nonsyndromic Deafness DisGeNET BeFree 2.566E-4 2.291E-3 1.609E-2
1.619E-1
 2 83
32 C0728829 Congenital pes cavus DisGeNET Curated 2.951E-4 2.291E-3 1.609E-2
1.862E-1
 2 89
33 C0473579 Porokeratotic eccrine ostial and dermal duct nevus DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
34 C1857499 Bony paranasal bossing DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
35 C1834056 Thin anteverted nares DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
36 C0266004 Knuckle pads, leuconychia and sensorineural deafness DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
37 C1857505 Club-shaped distal femora DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
38 C0553668 Labored breathing DisGeNET BeFree 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
39 C0010334 Crisscross Heart DisGeNET BeFree 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
40 cv:C0812437 Oculodentodigital dysplasia Clinical Variations 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
41 C0395976 Hearing loss associated with syndrome DisGeNET BeFree 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
42 OMIN:186100 SYNDACTYLY, TYPE III OMIM 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
43 C4023731 4-5 finger syndactyly DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
44 OMIN:148350 KERATODERMA, PALMOPLANTAR, WITH DEAFNESS OMIM 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
45 cv:C2675750 Deafness, autosomal dominant 3a Clinical Variations 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
46 C1852289 Autoamputation of digits DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
47 C3826233 Hearing impaired children DisGeNET BeFree 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
48 C1861366 SYNDACTYLY, TYPE III DisGeNET Curated 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
49 cv:C0152101 Hypoplastic left heart syndrome Clinical Variations 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
50 cv:C1857496 Craniometaphyseal dysplasia, autosomal recessive type Clinical Variations 3.085E-4 2.291E-3 1.609E-2
1.947E-1
 1 1
Show 45 more annotations