Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc376_9, positive side

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1: GO: Molecular Function [Display Chart] 9 input genes in category / 94 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005165 neurotrophin receptor binding 2.492E-11 2.342E-9 1.201E-8 2.342E-9 4 14
2 GO:0005167 neurotrophin TRK receptor binding 4.339E-9 2.039E-7 1.045E-6 4.078E-7 3 8
3 GO:0005168 neurotrophin TRKA receptor binding 4.337E-6 1.359E-4 6.965E-4 4.077E-4 2 7
4 GO:0005126 cytokine receptor binding 6.678E-6 1.569E-4 8.044E-4 6.277E-4 4 289
5 GO:0008083 growth factor activity 5.583E-5 1.050E-3 5.380E-3 5.248E-3 3 166
6 GO:0030971 receptor tyrosine kinase binding 3.607E-4 5.651E-3 2.897E-2 3.391E-2 2 60
7 GO:1990782 protein tyrosine kinase binding 4.365E-4 5.667E-3 2.905E-2 4.103E-2 2 66
8 GO:0070678 preprotein binding 4.823E-4 5.667E-3 2.905E-2 4.534E-2 1 1
9 GO:0005169 neurotrophin TRKB receptor binding 9.644E-4 9.065E-3 4.647E-2
9.065E-2
 1 2
10 GO:0005163 nerve growth factor receptor binding 9.644E-4 9.065E-3 4.647E-2
9.065E-2
 1 2
11 GO:0017137 Rab GTPase binding 1.654E-3 1.413E-2
7.244E-2
1.554E-1
 2 129
12 GO:0015379 potassium:chloride symporter activity 2.409E-3 1.887E-2
9.674E-2
2.265E-1
 1 5
13 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity 3.372E-3 2.264E-2
1.160E-1
3.169E-1
 1 7
14 GO:0048406 nerve growth factor binding 3.372E-3 2.264E-2
1.160E-1
3.169E-1
 1 7
15 GO:0015377 cation:chloride symporter activity 3.853E-3 2.414E-2
1.238E-1
3.621E-1
 1 8
16 GO:0019211 phosphatase activator activity 5.294E-3 2.927E-2
1.500E-1
4.976E-1
 1 11
17 GO:0043121 neurotrophin binding 5.294E-3 2.927E-2
1.500E-1
4.976E-1
 1 11
18 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity 5.774E-3 3.015E-2
1.546E-1
5.427E-1
 1 12
19 GO:0008191 metalloendopeptidase inhibitor activity 6.733E-3 3.241E-2
1.661E-1
6.329E-1
 1 14
20 GO:0031625 ubiquitin protein ligase binding 7.173E-3 3.241E-2
1.661E-1
6.743E-1
 2 273
21 GO:0044389 ubiquitin-like protein ligase binding 7.378E-3 3.241E-2
1.661E-1
6.935E-1
 2 277
22 GO:0017016 Ras GTPase binding 7.585E-3 3.241E-2
1.661E-1
7.130E-1
 2 281
23 GO:0030296 protein tyrosine kinase activator activity 8.650E-3 3.393E-2
1.739E-1
8.131E-1
 1 18
24 GO:0031267 small GTPase binding 8.662E-3 3.393E-2
1.739E-1
8.142E-1
 2 301
25 GO:0070530 K63-linked polyubiquitin modification-dependent protein binding 9.607E-3 3.537E-2
1.813E-1
9.030E-1
 1 20
26 GO:0005123 death receptor binding 1.008E-2 3.537E-2
1.813E-1
9.480E-1
 1 21
27 GO:0051020 GTPase binding 1.016E-2 3.537E-2
1.813E-1
9.550E-1
 2 327
28 GO:0000146 microfilament motor activity 1.104E-2 3.609E-2
1.850E-1
1.000E0
 1 23
29 GO:0005035 death receptor activity 1.152E-2 3.609E-2
1.850E-1
1.000E0
 1 24
30 GO:0005031 tumor necrosis factor-activated receptor activity 1.152E-2 3.609E-2
1.850E-1
1.000E0
 1 24
31 GO:0035255 ionotropic glutamate receptor binding 1.247E-2 3.782E-2
1.939E-1
1.000E0
 1 26
32 GO:0005104 fibroblast growth factor receptor binding 1.343E-2 3.944E-2
2.022E-1
1.000E0
 1 28
33 GO:0008519 ammonium transmembrane transporter activity 1.390E-2 3.960E-2
2.030E-1
1.000E0
 1 29
34 GO:0042169 SH2 domain binding 1.628E-2 4.373E-2
2.242E-1
1.000E0
 1 34
35 GO:0005158 insulin receptor binding 1.628E-2 4.373E-2
2.242E-1
1.000E0
 1 34
36 GO:0030546 receptor activator activity 1.676E-2 4.376E-2
2.243E-1
1.000E0
 1 35
37 GO:0001540 amyloid-beta binding 1.723E-2 4.378E-2
2.244E-1
1.000E0
 1 36
Show 32 more annotations

2: GO: Biological Process [Display Chart] 9 input genes in category / 576 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043524 negative regulation of neuron apoptotic process 6.236E-7 3.592E-4 2.491E-3 3.592E-4 4 159
2 GO:1901215 negative regulation of neuron death 1.688E-6 4.860E-4 3.370E-3 9.720E-4 4 204
3 GO:0043523 regulation of neuron apoptotic process 3.014E-6 5.787E-4 4.013E-3 1.736E-3 4 236
4 GO:0051402 neuron apoptotic process 4.495E-6 6.011E-4 4.168E-3 2.589E-3 4 261
5 GO:0007611 learning or memory 5.218E-6 6.011E-4 4.168E-3 3.006E-3 4 271
6 GO:0050772 positive regulation of axonogenesis 6.294E-6 6.042E-4 4.190E-3 3.625E-3 3 80
7 GO:0050890 cognition 8.117E-6 6.155E-4 4.268E-3 4.675E-3 4 303
8 GO:1901214 regulation of neuron death 8.549E-6 6.155E-4 4.268E-3 4.924E-3 4 307
9 GO:0048672 positive regulation of collateral sprouting 1.139E-5 7.292E-4 5.056E-3 6.562E-3 2 11
10 GO:0070997 neuron death 1.371E-5 7.895E-4 5.475E-3 7.895E-3 4 346
11 GO:0048670 regulation of collateral sprouting 4.772E-5 2.499E-3 1.733E-2 2.749E-2 2 22
12 GO:0061351 neural precursor cell proliferation 5.617E-5 2.579E-3 1.788E-2 3.235E-2 3 166
13 GO:0072089 stem cell proliferation 5.821E-5 2.579E-3 1.788E-2 3.353E-2 3 168
14 GO:0048011 neurotrophin TRK receptor signaling pathway 6.707E-5 2.759E-3 1.913E-2 3.863E-2 2 26
15 GO:0010770 positive regulation of cell morphogenesis involved in differentiation 7.507E-5 2.883E-3 1.999E-2 4.324E-2 3 183
16 GO:0050770 regulation of axonogenesis 8.133E-5 2.928E-3 2.030E-2 4.685E-2 3 188
17 GO:0048668 collateral sprouting 8.968E-5 3.039E-3 2.107E-2
5.166E-2
 2 30
18 GO:0038179 neurotrophin signaling pathway 1.155E-4 3.697E-3 2.564E-2
6.655E-2
 2 34
19 GO:0016358 dendrite development 1.656E-4 5.020E-3 3.481E-2
9.539E-2
 3 239
20 GO:0001662 behavioral fear response 1.856E-4 5.324E-3 3.692E-2
1.069E-1
 2 43
21 GO:0002209 behavioral defense response 1.943E-4 5.324E-3 3.692E-2
1.119E-1
 2 44
22 GO:0045773 positive regulation of axon extension 2.033E-4 5.324E-3 3.692E-2
1.171E-1
 2 45
23 GO:0042596 fear response 2.219E-4 5.557E-3 3.854E-2
1.278E-1
 2 47
24 GO:2000027 regulation of animal organ morphogenesis 2.322E-4 5.572E-3 3.864E-2
1.337E-1
 3 268
25 GO:0010976 positive regulation of neuron projection development 2.811E-4 6.477E-3 4.491E-2
1.619E-1
 3 286
26 GO:0000186 activation of MAPKK activity 3.268E-4 7.240E-3
5.020E-2
1.882E-1
 2 57
27 GO:0007405 neuroblast proliferation 3.744E-4 7.986E-3
5.538E-2
2.156E-1
 2 61
28 GO:0060079 excitatory postsynaptic potential 4.516E-4 9.279E-3
6.434E-2
2.601E-1
 2 67
29 GO:0040040 thermosensory behavior 4.833E-4 9.279E-3
6.434E-2
2.784E-1
 1 1
30 GO:0031550 positive regulation of brain-derived neurotrophic factor receptor signaling pathway 4.833E-4 9.279E-3
6.434E-2
2.784E-1
 1 1
31 GO:0050804 modulation of chemical synaptic transmission 5.385E-4 1.001E-2
6.939E-2
3.102E-1
 3 357
32 GO:0021675 nerve development 5.808E-4 1.002E-2
6.951E-2
3.346E-1
 2 76
33 GO:0031346 positive regulation of cell projection organization 5.838E-4 1.002E-2
6.951E-2
3.363E-1
 3 367
34 GO:0001101 response to acid chemical 6.073E-4 1.002E-2
6.951E-2
3.498E-1
 3 372
35 GO:0010769 regulation of cell morphogenesis involved in differentiation 6.169E-4 1.002E-2
6.951E-2
3.553E-1
 3 374
36 GO:0045666 positive regulation of neuron differentiation 6.265E-4 1.002E-2
6.951E-2
3.609E-1
 3 376
37 GO:0060996 dendritic spine development 7.603E-4 1.184E-2
8.207E-2
4.379E-1
 2 87
38 GO:0033555 multicellular organismal response to stress 8.681E-4 1.256E-2
8.707E-2
5.000E-1
 2 93
39 GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process 8.681E-4 1.256E-2
8.707E-2
5.000E-1
 2 93
40 GO:2000177 regulation of neural precursor cell proliferation 9.056E-4 1.256E-2
8.707E-2
5.216E-1
 2 95
41 GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 9.247E-4 1.256E-2
8.707E-2
5.326E-1
 2 96
42 GO:0061193 taste bud development 9.663E-4 1.256E-2
8.707E-2
5.566E-1
 1 2
43 GO:0046619 optic placode formation involved in camera-type eye formation 9.663E-4 1.256E-2
8.707E-2
5.566E-1
 1 2
44 GO:2000117 negative regulation of cysteine-type endopeptidase activity 9.829E-4 1.256E-2
8.707E-2
5.662E-1
 2 99
45 GO:0097202 activation of cysteine-type endopeptidase activity 1.003E-3 1.256E-2
8.707E-2
5.776E-1
 2 100
46 GO:0060078 regulation of postsynaptic membrane potential 1.003E-3 1.256E-2
8.707E-2
5.776E-1
 2 100
47 GO:0030516 regulation of axon extension 1.084E-3 1.328E-2
9.211E-2
6.243E-1
 2 104
48 GO:0050769 positive regulation of neurogenesis 1.161E-3 1.373E-2
9.522E-2
6.689E-1
 3 465
49 GO:0099565 chemical synaptic transmission, postsynaptic 1.168E-3 1.373E-2
9.522E-2
6.728E-1
 2 108
50 GO:0072091 regulation of stem cell proliferation 1.233E-3 1.391E-2
9.647E-2
7.104E-1
 2 111
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 9 input genes in category / 67 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0043204 perikaryon 3.291E-5 2.205E-3 1.056E-2 2.205E-3 3 142
2 GO:0032590 dendrite membrane 9.150E-5 3.065E-3 1.468E-2 6.131E-3 2 31
3 GO:0032589 neuron projection membrane 2.304E-4 5.145E-3 2.464E-2 1.544E-2 2 49
4 GO:0044754 autolysosome 9.441E-4 1.096E-2
5.247E-2
6.326E-2
 1 2
5 GO:0044753 amphisome 9.441E-4 1.096E-2
5.247E-2
6.326E-2
 1 2
6 GO:0098794 postsynapse 9.811E-4 1.096E-2
5.247E-2
6.574E-2
 3 449
7 GO:0031256 leading edge membrane 2.136E-3 2.044E-2
9.791E-2
1.431E-1
 2 150
8 GO:0005767 secondary lysosome 3.772E-3 3.159E-2
1.513E-1
2.527E-1
 1 8
9 GO:0045179 apical cortex 4.713E-3 3.473E-2
1.663E-1
3.158E-1
 1 10
10 GO:0030061 mitochondrial crista 5.183E-3 3.473E-2
1.663E-1
3.473E-1
 1 11
11 GO:0097225 sperm midpiece 8.000E-3 4.873E-2
2.334E-1
5.360E-1
 1 17
12 GO:0099738 cell cortex region 8.937E-3 4.990E-2
2.390E-1
5.988E-1
 1 19
Show 7 more annotations

4: Human Phenotype [Display Chart] 5 input genes in category / 418 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 9 input genes in category / 579 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0006258 abnormal circumvallate papillae morphology 2.014E-6 1.165E-3 8.087E-3 1.166E-3 2 3
2 MP:0006260 abnormal gustatory papillae taste bud morphology 4.026E-6 1.165E-3 8.087E-3 2.331E-3 2 4
3 MP:0001002 abnormal taste bud morphology 1.006E-5 1.455E-3 1.010E-2 5.822E-3 2 6
4 MP:0005500 abnormal gustatory system morphology 1.006E-5 1.455E-3 1.010E-2 5.822E-3 2 6
5 MP:0001021 small L4 dorsal root ganglion 1.407E-5 1.551E-3 1.076E-2 8.147E-3 2 7
6 MP:0001019 abnormal L4 dorsal root ganglion morphology 1.875E-5 1.551E-3 1.076E-2 1.086E-2 2 8
7 MP:0008960 abnormal axon pruning 1.875E-5 1.551E-3 1.076E-2 1.086E-2 2 8
8 MP:0006256 abnormal gustatory papillae morphology 2.410E-5 1.744E-3 1.210E-2 1.395E-2 2 9
9 MP:0008947 increased neuron number 8.613E-5 5.541E-3 3.845E-2 4.987E-2 3 107
10 MP:0000968 abnormal sensory neuron innervation pattern 1.040E-4 5.998E-3 4.162E-2
6.023E-2
 3 114
11 MP:0006404 abnormal lumbar dorsal root ganglion morphology 1.140E-4 5.998E-3 4.162E-2
6.598E-2
 2 19
12 MP:0005236 abnormal olfactory nerve morphology 1.683E-4 8.120E-3
5.635E-2
9.745E-2
 2 23
13 MP:0003212 increased susceptibility to age related obesity 1.994E-4 8.783E-3
6.095E-2
1.154E-1
 2 25
14 MP:0000961 abnormal dorsal root ganglion morphology 2.124E-4 8.783E-3
6.095E-2
1.230E-1
 3 145
15 MP:0000764 abnormal tongue epithelium morphology 2.693E-4 1.040E-2
7.215E-2
1.560E-1
 2 29
16 MP:0000964 small dorsal root ganglion 3.497E-4 1.265E-2
8.780E-2
2.024E-1
 2 33
17 MP:0001963 abnormal hearing physiology 3.985E-4 1.357E-2
9.419E-2
2.307E-1
 4 458
18 MP:0001290 delayed eyelid opening 4.402E-4 1.363E-2
9.457E-2
2.549E-1
 2 37
19 MP:0000849 abnormal cerebellum morphology 4.472E-4 1.363E-2
9.457E-2
2.589E-1
 4 472
20 MP:0004101 abnormal brain interneuron morphology 6.234E-4 1.805E-2
1.252E-1
3.609E-1
 2 44
21 MP:0001363 increased anxiety-related response 7.134E-4 1.967E-2
1.365E-1
4.130E-1
 3 219
22 MP:0008987 abnormal liver lobule morphology 9.541E-4 2.494E-2
1.731E-1
5.524E-1
 3 242
23 MP:0002184 abnormal innervation 1.001E-3 2.494E-2
1.731E-1
5.794E-1
 3 246
24 MP:0008986 abnormal liver parenchyma morphology 1.111E-3 2.494E-2
1.731E-1
6.431E-1
 3 255
25 MP:0000960 abnormal sensory ganglion morphology 1.111E-3 2.494E-2
1.731E-1
6.431E-1
 3 255
26 MP:0001092 abnormal trigeminal ganglion morphology 1.120E-3 2.494E-2
1.731E-1
6.484E-1
 2 59
27 MP:0001513 limb grasping 1.283E-3 2.739E-2
1.901E-1
7.427E-1
 3 268
28 MP:0003202 abnormal neuron apoptosis 1.325E-3 2.739E-2
1.901E-1
7.670E-1
 3 271
29 MP:0001504 abnormal posture 1.471E-3 2.795E-2
1.939E-1
8.516E-1
 3 281
30 MP:0004874 abnormal timing of postnatal eyelid opening 1.485E-3 2.795E-2
1.939E-1
8.598E-1
 2 68
31 MP:0001257 increased body length 1.709E-3 2.795E-2
1.939E-1
9.896E-1
 2 73
32 MP:0011040 abnormal vestibuloocular light reflex 1.738E-3 2.795E-2
1.939E-1
1.000E0
 1 2
33 MP:0009972 absent hippocampus pyramidal cells 1.738E-3 2.795E-2
1.939E-1
1.000E0
 1 2
34 MP:0014080 fused small intestinal villi 1.738E-3 2.795E-2
1.939E-1
1.000E0
 1 2
35 MP:0009975 absent cerebral cortex pyramidal cells 1.738E-3 2.795E-2
1.939E-1
1.000E0
 1 2
36 MP:0000907 small mesencephalic trigeminal nucleus 1.738E-3 2.795E-2
1.939E-1
1.000E0
 1 2
37 MP:0006055 abnormal vascular endothelial cell morphology 1.949E-3 2.969E-2
2.060E-1
1.000E0
 2 78
38 MP:0001007 abnormal sympathetic system morphology 1.949E-3 2.969E-2
2.060E-1
1.000E0
 2 78
39 MP:0010124 decreased bone mineral content 2.119E-3 3.114E-2
2.161E-1
1.000E0
 3 319
40 MP:0009936 abnormal dendritic spine morphology 2.151E-3 3.114E-2
2.161E-1
1.000E0
 2 82
41 MP:0000745 tremors 2.255E-3 3.184E-2
2.210E-1
1.000E0
 3 326
42 MP:0002855 abnormal cochlear ganglion morphology 2.363E-3 3.258E-2
2.261E-1
1.000E0
 2 86
43 MP:0004747 abnormal cochlear OHC afferent innervation pattern 2.605E-3 3.279E-2
2.276E-1
1.000E0
 1 3
44 MP:0003470 abnormal summary potential 2.605E-3 3.279E-2
2.276E-1
1.000E0
 1 3
45 MP:0001026 abnormal adrenergic neuron morphology 2.605E-3 3.279E-2
2.276E-1
1.000E0
 1 3
46 MP:0000856 abnormal cerebellar plate morphology 2.605E-3 3.279E-2
2.276E-1
1.000E0
 1 3
47 MP:0001362 abnormal anxiety-related response 2.994E-3 3.688E-2
2.559E-1
1.000E0
 3 360
48 MP:0009489 abnormal blood vessel endothelium morphology 3.118E-3 3.761E-2
2.610E-1
1.000E0
 2 99
49 MP:0000807 abnormal hippocampus morphology 3.237E-3 3.825E-2
2.654E-1
1.000E0
 3 370
50 MP:0000801 abnormal temporal lobe morphology 3.388E-3 3.924E-2
2.723E-1
1.000E0
 3 376
Show 45 more annotations

6: Domain [Display Chart] 9 input genes in category / 84 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR019846 Nerve growth factor CS InterPro 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
2 PS00248 NGF 1 PROSITE 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
3 SM00140 NGF SMART 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
4 PS50270 NGF 2 PROSITE 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
5 IPR002072 Nerve growth factor-rel InterPro 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
6 PD002052 Nerve growth factor-rel ProDom 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
7 PF00243 NGF Pfam 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
8 IPR020408 Nerve growth factor-like InterPro 1.230E-6 1.292E-5 6.477E-5 1.033E-4 2 4
9 2.10.90.10 - Gene3D 4.463E-4 1.922E-3 9.635E-3 3.749E-2 2 67
10 IPR029034 Cystine-knot cytokine InterPro 4.463E-4 1.922E-3 9.635E-3 3.749E-2 2 67
11 IPR020437 Nerve growth factor bsu mml InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
12 IPR033741 SQSTM UBA InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
13 PF10491 Nrf1 DNA-bind Pfam 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
14 IPR020430 Brain-der neurotrophic factor InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
15 IPR019526 Nrf1 activation-bd InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
16 PF16577 UBA 5 Pfam 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
17 PF10492 Nrf1 activ bdg Pfam 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
18 IPR030358 KCC2 InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
19 IPR022325 TNFR 16 InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
20 IPR019525 Nrf1 NLS/DNA-bd dimer InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
21 IPR020425 Nerve growth factor bsu InterPro 4.804E-4 1.922E-3 9.635E-3 4.035E-2 1 1
22 SM00193 PTN SMART 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
23 PD005592 PTN MK hepar bd ProDom 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
24 IPR000762 Midkine heparin-bd GF InterPro 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
25 IPR020092 PTN MK heparin-bd GF CS InterPro 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
26 PS00620 PTN MK 2 PROSITE 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
27 IPR020091 PTN/MK diS InterPro 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
28 IPR020089 PTN/MK N dom InterPro 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
29 PS00619 PTN MK 1 PROSITE 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
30 IPR020090 PTN/MK C dom InterPro 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
31 PF05196 PTN MK N Pfam 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
32 PF01091 PTN MK C Pfam 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
33 2.20.60.10 - Gene3D 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
34 2.30.90.10 - Gene3D 9.606E-4 2.373E-3 1.190E-2
8.069E-2
 1 2
35 IPR000076 KCL cotranspt InterPro 1.920E-3 4.609E-3 2.311E-2
1.613E-1
 1 4
36 IPR008989 Myosin S1 N InterPro 2.400E-3 5.600E-3 2.808E-2
2.016E-1
 1 5
37 IPR002710 Dilute dom InterPro 2.879E-3 6.046E-3 3.032E-2
2.419E-1
 1 6
38 PS51126 DILUTE PROSITE 2.879E-3 6.046E-3 3.032E-2
2.419E-1
 1 6
39 PF01843 DIL Pfam 2.879E-3 6.046E-3 3.032E-2
2.419E-1
 1 6
40 SM01132 DIL SMART 2.879E-3 6.046E-3 3.032E-2
2.419E-1
 1 6
41 IPR002100 TF MADSbox InterPro 3.358E-3 6.717E-3 3.368E-2
2.821E-1
 1 7
42 IPR004842 SLC12A fam InterPro 3.358E-3 6.717E-3 3.368E-2
2.821E-1
 1 7
43 PF03522 SLC12 Pfam 3.837E-3 7.326E-3 3.673E-2
3.223E-1
 1 8
44 IPR018491 SLC12 C InterPro 3.837E-3 7.326E-3 3.673E-2
3.223E-1
 1 8
45 SM00310 PTBI SMART 5.273E-3 9.843E-3 4.935E-2
4.429E-1
 1 11
46 PS51064 IRS PTB PROSITE 5.751E-3 1.050E-2
5.266E-2
4.831E-1
 1 12
47 PF02174 IRS Pfam 6.707E-3 1.083E-2
5.432E-2
5.634E-1
 1 14
48 SM00666 PB1 SMART 6.707E-3 1.083E-2
5.432E-2
5.634E-1
 1 14
49 IPR002404 IRS PTB InterPro 6.707E-3 1.083E-2
5.432E-2
5.634E-1
 1 14
50 PF00564 PB1 Pfam 6.707E-3 1.083E-2
5.432E-2
5.634E-1
 1 14
Show 45 more annotations

7: Pathway [Display Chart] 9 input genes in category / 165 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 137977 Neurotrophic factor-mediated Trk receptor signaling BioSystems: Pathway Interaction Database 1.906E-10 3.145E-8 1.788E-7 3.145E-8 5 56
2 138019 p75(NTR)-mediated signaling BioSystems: Pathway Interaction Database 6.452E-8 3.905E-6 2.221E-5 1.065E-5 4 61
3 1269454 NF-kB is activated and signals survival BioSystems: REACTOME 9.471E-8 3.905E-6 2.221E-5 1.563E-5 3 14
4 1269453 p75NTR recruits signalling complexes BioSystems: REACTOME 9.471E-8 3.905E-6 2.221E-5 1.563E-5 3 14
5 1269449 NRIF signals cell death from the nucleus BioSystems: REACTOME 1.183E-7 3.905E-6 2.221E-5 1.953E-5 3 15
6 1269452 p75NTR signals via NF-kB BioSystems: REACTOME 1.767E-7 4.860E-6 2.764E-5 2.916E-5 3 17
7 1269446 NFG and proNGF binds to p75NTR BioSystems: REACTOME 4.645E-7 1.095E-5 6.226E-5 7.665E-5 2 2
8 101143 Neurotrophin signaling pathway BioSystems: KEGG 9.635E-7 1.987E-5 1.130E-4 1.590E-4 4 119
9 1269455 Ceramide signalling BioSystems: REACTOME 1.393E-6 2.554E-5 1.452E-4 2.299E-4 2 3
10 1269457 Axonal growth stimulation BioSystems: REACTOME 2.785E-6 4.596E-5 2.613E-4 4.596E-4 2 4
11 1269451 p75NTR negatively regulates cell cycle via SC1 BioSystems: REACTOME 6.958E-6 9.567E-5 5.440E-4 1.148E-3 2 6
12 1269450 NADE modulates death signalling BioSystems: REACTOME 6.958E-6 9.567E-5 5.440E-4 1.148E-3 2 6
13 1269447 Cell death signalling via NRAGE, NRIF and NADE BioSystems: REACTOME 1.934E-5 2.455E-4 1.396E-3 3.191E-3 3 78
14 1269456 p75NTR regulates axonogenesis BioSystems: REACTOME 2.546E-5 2.801E-4 1.593E-3 4.202E-3 2 11
15 M89 Phosphorylation of MEK1 by cdk5/p35 down regulates the MAP kinase pathway MSigDB C2 BIOCARTA (v6.0) 2.546E-5 2.801E-4 1.593E-3 4.202E-3 2 11
16 1269445 p75 NTR receptor-mediated signalling BioSystems: REACTOME 4.078E-5 4.206E-4 2.391E-3 6.729E-3 3 100
17 M18895 The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. MSigDB C2 BIOCARTA (v6.0) 6.282E-5 6.098E-4 3.467E-3 1.037E-2 2 17
18 M7860 Nerve growth factor pathway (NGF) MSigDB C2 BIOCARTA (v6.0) 7.065E-5 6.476E-4 3.683E-3 1.166E-2 2 18
19 M287 Erk1/Erk2 Mapk Signaling pathway MSigDB C2 BIOCARTA (v6.0) 1.739E-4 1.510E-3 8.587E-3 2.869E-2 2 28
20 1269443 Signalling by NGF BioSystems: REACTOME 2.413E-4 1.991E-3 1.132E-2 3.981E-2 4 483
21 PW:0000369 the ARE-Nrf mediated of drug-metabolizing enzyme expression Pathway Ontology 7.229E-4 5.680E-3 3.230E-2
1.193E-1
 1 1
22 1269448 NRAGE signals death through JNK BioSystems: REACTOME 8.589E-4 6.442E-3 3.663E-2
1.417E-1
 2 62
23 138035 Glypican 2 network BioSystems: Pathway Interaction Database 1.445E-3 9.937E-3
5.650E-2
2.385E-1
 1 2
24 1269462 TRKA activation by NGF BioSystems: REACTOME 1.445E-3 9.937E-3
5.650E-2
2.385E-1
 1 2
25 M5883 Genes encoding secreted soluble factors MSigDB C2 BIOCARTA (v6.0) 1.552E-3 1.024E-2
5.824E-2
2.560E-1
 3 344
26 1269474 Signalling to STAT3 BioSystems: REACTOME 2.167E-3 1.375E-2
7.821E-2
3.576E-1
 1 3
27 1269444 NGF processing BioSystems: REACTOME 2.889E-3 1.765E-2
1.004E-1
4.766E-1
 1 4
28 1269473 PI3K/AKT activation BioSystems: REACTOME 3.601E-3 2.122E-2
1.207E-1
5.942E-1
 2 128
29 1269461 Activation of TRKA receptors BioSystems: REACTOME 4.330E-3 2.464E-2
1.401E-1
7.145E-1
 1 6
30 1269912 Cation-coupled Chloride cotransporters BioSystems: REACTOME 5.050E-3 2.778E-2
1.579E-1
8.333E-1
 1 7
31 1269459 Regulated proteolysis of p75NTR BioSystems: REACTOME 7.208E-3 3.604E-2
2.049E-1
1.000E0
 1 10
32 1383048 Signaling by FGFR3 fusions in cancer BioSystems: REACTOME 7.208E-3 3.604E-2
2.049E-1
1.000E0
 1 10
33 1269458 Axonal growth inhibition (RHOA activation) BioSystems: REACTOME 7.208E-3 3.604E-2
2.049E-1
1.000E0
 1 10
34 1268877 Signaling by FGFR4 in disease BioSystems: REACTOME 7.926E-3 3.777E-2
2.148E-1
1.000E0
 1 11
35 83100 Huntington's disease BioSystems: KEGG 8.012E-3 3.777E-2
2.148E-1
1.000E0
 2 193
36 M9134 Trka Receptor Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 8.644E-3 3.962E-2
2.253E-1
1.000E0
 1 12
37 PW:0000713 vasopressin signaling pathway via receptor type 2 Pathway Ontology 9.361E-3 4.094E-2
2.328E-1
1.000E0
 1 13
38 868086 Rap1 signaling pathway BioSystems: KEGG 9.429E-3 4.094E-2
2.328E-1
1.000E0
 2 210
39 1269476 Retrograde neurotrophin signalling BioSystems: REACTOME 1.008E-2 4.264E-2
2.425E-1
1.000E0
 1 14
40 868085 Ras signaling pathway BioSystems: KEGG 1.095E-2 4.466E-2
2.539E-1
1.000E0
 2 227
41 PW:0000491 vasopressin signaling Pathway Ontology 1.223E-2 4.466E-2
2.539E-1
1.000E0
 1 17
42 1269417 PI-3K cascade:FGFR3 BioSystems: REACTOME 1.294E-2 4.466E-2
2.539E-1
1.000E0
 1 18
43 1269471 ARMS-mediated activation BioSystems: REACTOME 1.338E-2 4.466E-2
2.539E-1
1.000E0
 2 252
44 1269468 Signalling to p38 via RIT and RIN BioSystems: REACTOME 1.338E-2 4.466E-2
2.539E-1
1.000E0
 2 252
45 1269470 Frs2-mediated activation BioSystems: REACTOME 1.348E-2 4.466E-2
2.539E-1
1.000E0
 2 253
46 1269469 Prolonged ERK activation events BioSystems: REACTOME 1.368E-2 4.466E-2
2.539E-1
1.000E0
 2 255
47 83048 MAPK signaling pathway BioSystems: KEGG 1.368E-2 4.466E-2
2.539E-1
1.000E0
 2 255
48 1269465 Signalling to RAS BioSystems: REACTOME 1.409E-2 4.466E-2
2.539E-1
1.000E0
 2 259
49 PW:0000017 Huntington disease Pathway Ontology 1.437E-2 4.466E-2
2.539E-1
1.000E0
 1 20
50 1269426 PI-3K cascade:FGFR4 BioSystems: REACTOME 1.437E-2 4.466E-2
2.539E-1
1.000E0
 1 20
Show 45 more annotations

8: Pubmed [Display Chart] 9 input genes in category / 5528 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 18349525 Expression patterns of neurotrophins and neurotrophin receptors in articular chondrocytes and inflammatory infiltrates in knee joint arthritis. Pubmed 9.047E-12 5.001E-8 4.599E-7 5.001E-8 3 3
2 18780967 SNPs in neurotrophin system genes and Alzheimer's disease in an Italian population. Pubmed 9.045E-11 2.500E-7 2.298E-6 5.000E-7 3 5
3 10985348 NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor-dependent apoptosis. Pubmed 1.809E-10 2.500E-7 2.298E-6 9.999E-7 3 6
4 8050673 Role of neurotrophins in mouse neuronal development. Pubmed 1.809E-10 2.500E-7 2.298E-6 9.999E-7 3 6
5 24908487 SorCS2 regulates dopaminergic wiring and is processed into an apoptotic two-chain receptor in peripheral glia. Pubmed 3.165E-10 3.499E-7 3.217E-6 1.750E-6 3 7
6 9640332 Differential dependency of unmyelinated and A delta epidermal and upper dermal innervation on neurotrophins, trk receptors, and p75LNGFR. Pubmed 5.063E-10 3.499E-7 3.217E-6 2.799E-6 3 8
7 15376326 Pacinian corpuscle development involves multiple Trk signaling pathways. Pubmed 5.063E-10 3.499E-7 3.217E-6 2.799E-6 3 8
8 9331334 Differential dependency of cutaneous mechanoreceptors on neurotrophins, trk receptors, and P75 LNGFR. Pubmed 5.063E-10 3.499E-7 3.217E-6 2.799E-6 3 8
9 18323418 A model for neuronal competition during development. Pubmed 7.594E-10 4.198E-7 3.860E-6 4.198E-6 3 9
10 11244088 The atypical protein kinase C-interacting protein p62 is a scaffold for NF-kappaB activation by nerve growth factor. Pubmed 7.594E-10 4.198E-7 3.860E-6 4.198E-6 3 9
11 10491653 Spatiotemporal patterns of expression of neurotrophins and neurotrophin receptors in mice suggest functional roles in testicular and epididymal morphogenesis. Pubmed 1.085E-9 4.613E-7 4.241E-6 5.997E-6 3 10
12 20219210 Role of the neurotrophin network in eating disorders' subphenotypes: body mass index and age at onset of the disease. Pubmed 1.085E-9 4.613E-7 4.241E-6 5.997E-6 3 10
13 18203754 Association of NTRK3 and its interaction with NGF suggest an altered cross-regulation of the neurotrophin signaling pathway in eating disorders. Pubmed 1.085E-9 4.613E-7 4.241E-6 5.997E-6 3 10
14 23785138 p75 neurotrophin receptor is a clock gene that regulates oscillatory components of circadian and metabolic networks. Pubmed 1.491E-9 5.496E-7 5.054E-6 8.244E-6 3 11
15 9252186 A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB. Pubmed 1.491E-9 5.496E-7 5.054E-6 8.244E-6 3 11
16 16630834 Ligand-dependent cleavage of the P75 neurotrophin receptor is necessary for NRIF nuclear translocation and apoptosis in sympathetic neurons. Pubmed 3.289E-9 1.069E-6 9.834E-6 1.818E-5 3 14
17 10022904 Activation of IkappaB kinase beta by protein kinase C isoforms. Pubmed 3.289E-9 1.069E-6 9.834E-6 1.818E-5 3 14
18 16997282 NF-kappaB functions in the nervous system: from development to disease. Pubmed 5.059E-9 1.472E-6 1.353E-5 2.796E-5 3 16
19 15721744 p75NTR--live or let die. Pubmed 5.059E-9 1.472E-6 1.353E-5 2.796E-5 3 16
20 28253191 β-NGF and β-NGF receptor upregulation in blood and synovial fluid in osteoarthritis. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
21 25595986 NGF but not BDNF overexpression protects hippocampal LTP from beta-amyloid-induced impairment. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
22 19334503 [Selective anxiolytic afobazole increases the content of BDNF and NGF in cultured hippocampal HT-22 line neurons]. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
23 23322532 Overexpression of nerve growth factor by murine smooth muscle cells: role of the p75 neurotrophin receptor on sympathetic and sensory sprouting. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
24 19193386 Bone marrow stromal cell therapy reduces proNGF and p75 expression in mice with experimental autoimmune encephalomyelitis. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
25 12531456 Modulation of cytokine mRNA expression by brain-derived neurotrophic factor and nerve growth factor in human immune cells. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
26 27577679 Nerve growth factor (NGF)-mediated regulation of p75(NTR) expression contributes to chemotherapeutic resistance in triple negative breast cancer cells. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
27 23034254 Nerve growth factor and brain-derived neurotrophic factor concentrations in schizophrenia: a review. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
28 19560628 Relation between plasma brain-derived neurotrophic factor and nerve growth factor in the male patients with alcohol dependence. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
29 26015580 BDNF pro-peptide actions facilitate hippocampal LTD and are altered by the common BDNF polymorphism Val66Met. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
30 25064020 Serum brain-derived neurotrophic factor and nerve growth factor decreased in chronic ketamine abusers. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
31 27251195 Peripheral Brain Derived Neurotrophic Factor Precursor Regulates Pain as an Inflammatory Mediator. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
32 19758188 NGF and its receptor system: a new dimension in the pathogenesis of psoriasis and psoriatic arthritis. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
33 15131306 Structure of nerve growth factor complexed with the shared neurotrophin receptor p75. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
34 18709654 The p75 receptor is associated with inflammatory thermal hypersensitivity. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
35 19038326 Variation in the BDNF and NGFB genes in German atopic dermatitis patients. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
36 18830907 Brain-derived neurotrophic factor and nerve growth factor correlate with T-cell activation in primary Sjogren's syndrome. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
37 17610817 Polarized signaling endosomes coordinate BDNF-induced chemotaxis of cerebellar precursors. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
38 21366730 Endogenous proBDNF is a negative regulator of migration of cerebellar granule cells in neonatal mice. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
39 25662808 Estrogen induced changes in uterine brain-derived neurotrophic factor and its receptors. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
40 23128606 Serum brain-derived neurotrophic factor and nerve growth factor concentrations change after alcohol withdrawal: preliminary data of a case-control comparison. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
41 19958603 Mucosal expression of nerve growth factor and brain-derived neurotrophic factor in chronic rhinosinusitis. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
42 26066836 NGF Expression in Reelin-Deprived Retinal Cells: A Potential Neuroprotective Effect. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
43 23633509 ProNGF promotes neurite growth from a subset of NGF-dependent neurons by a p75NTR-dependent mechanism. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
44 28068360 Exploring Serum Levels of Brain Derived Neurotrophic Factor and Nerve Growth Factor Across Glaucoma Stages. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
45 10377349 Functionally antagonistic interactions between the TrkA and p75 neurotrophin receptors regulate sympathetic neuron growth and target innervation. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
46 29799860 Neurotrophic factors and hippocampal activity in PTSD. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
47 20680101 NGF and NGF-receptor expression of cultured immortalized human corneal endothelial cells. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
48 29499660 Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
49 20219632 Distinct signaling pathways of precursor BDNF and mature BDNF in cultured cerebellar granule neurons. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
50 12595234 Regional expression of p75NTR contributes to neurotrophin regulation of cerebellar patterning. Pubmed 4.936E-8 4.013E-6 3.690E-5 2.729E-4 2 2
Show 45 more annotations

9: Interaction [Display Chart] 9 input genes in category / 506 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:NTRK2 NTRK2 interactions 2.256E-9 1.142E-6 7.768E-6 1.142E-6 4 38
2 int:NTRK3 NTRK3 interactions 2.102E-6 4.191E-4 2.852E-3 1.063E-3 3 53
3 int:NGFR NGFR interactions 2.485E-6 4.191E-4 2.852E-3 1.257E-3 3 56
4 int:NTF4 NTF4 interactions 4.818E-6 6.095E-4 4.148E-3 2.438E-3 2 7
5 int:NGF NGF interactions 8.256E-6 8.355E-4 5.685E-3 4.177E-3 2 9
6 int:ZNF274 ZNF274 interactions 3.500E-5 2.779E-3 1.891E-2 1.771E-2 2 18
7 int:SORT1 SORT1 interactions 3.844E-5 2.779E-3 1.891E-2 1.945E-2 3 139
8 int:NCAM1 NCAM1 interactions 2.669E-4 1.688E-2
1.149E-1
1.350E-1
 2 49
9 int:PLG PLG interactions 4.994E-4 2.762E-2
1.880E-1
2.527E-1
 2 67
10 int:MAPK1 MAPK1 interactions 5.459E-4 2.762E-2
1.880E-1
2.762E-1
 3 341
11 int:NFE2L2 NFE2L2 interactions 6.089E-4 2.801E-2
1.906E-1
3.081E-1
 2 74
Show 6 more annotations

10: Cytoband [Display Chart] 9 input genes in category / 9 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 17q21-q22 17q21-q22 2.076E-3 1.281E-2 3.623E-2 1.868E-2 1 8
2 18q21 18q21 4.665E-3 1.281E-2 3.623E-2 4.198E-2 1 18
3 5q35 5q35 6.215E-3 1.281E-2 3.623E-2
5.594E-2
 1 24
4 7q32 7q32 6.215E-3 1.281E-2 3.623E-2
5.594E-2
 1 24
5 12q15 12q15 8.537E-3 1.281E-2 3.623E-2
7.683E-2
 1 33
6 1p13.1 1p13.1 8.537E-3 1.281E-2 3.623E-2
7.683E-2
 1 33
7 11p13 11p13 1.547E-2 1.989E-2
5.628E-2
1.393E-1
 1 60
8 20q13.12 20q13.12 1.803E-2 2.029E-2
5.739E-2
1.623E-1
 1 70
9 11p11.2 11p11.2 2.262E-2 2.262E-2
6.400E-2
2.036E-1
 1 88
Show 4 more annotations

11: Transcription Factor Binding Site [Display Chart] 8 input genes in category / 185 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$CP2 02 V$CP2 02 3.891E-4 3.599E-2
2.088E-1
7.198E-2
 3 192
2 V$AREB6 03 V$AREB6 03 3.891E-4 3.599E-2
2.088E-1
7.198E-2
 3 192

12: Gene Family [Display Chart] 6 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1100 Myosins, class V genenames.org 9.891E-4 5.934E-3 1.454E-2 5.934E-3 1 3
2 542 Endogenous ligands genenames.org 2.449E-3 7.346E-3 1.800E-2 1.469E-2 2 237
3 91 Zinc fingers ZZ-type genenames.org 5.922E-3 1.184E-2 2.902E-2 3.553E-2 1 18
4 782 Tumor necrosis factor receptor superfamily genenames.org 9.527E-3 1.429E-2 3.501E-2
5.716E-2
 1 29

13: Coexpression [Display Chart] 9 input genes in category / 877 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 15246160-table5 Human StemCell Shim04 12genes GeneSigDB 8.859E-6 7.770E-3
5.714E-2
 7.770E-3 2 12
2 M9652 Genes up-regulated in CD4 [GeneID=920] T helper cells (52h): Th0 versus Th17 treated with TGFB1, IL6 [GeneID=7040;3569] and IL-23. MSigDB C7: Immunologic Signatures (v6.0) 5.144E-5 1.198E-2
8.809E-2
 4.511E-2 3 200
3 17823238-TableS4a Mouse EmbryonicStemCell Soh07 224genes A GeneSigDB 6.117E-5 1.198E-2
8.809E-2
5.365E-2
 3 212
4 M1466 Genes up-regulated in MEF cells (embryonic fibroblast) expressing ~25% of YY1 [GeneID=7528]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.290E-5 1.198E-2
8.809E-2
5.517E-2
 3 214
5 17823238-TableS4b Human EmbryonicStemCell Soh07 224genes B GeneSigDB 6.829E-5 1.198E-2
8.809E-2
5.989E-2
 3 220
6 17096850-Table2 Human Lung Balko06 50genes GeneSigDB 1.632E-4 2.385E-2
1.754E-1
1.431E-1
 2 50
7 15665281-Table2 Human Brain Wong05 96genes GeneSigDB 2.935E-4 3.677E-2
2.704E-1
2.574E-1
 2 67
8 20460173-ImmPortCytokines Human Immune Kong10 456genes ImmPort Cytokines GeneSigDB 5.028E-4 4.849E-2
3.566E-1
4.409E-1
 3 433
9 16611997-SuppTable1 Mouse StemCell Affar06 525genes GeneSigDB 5.269E-4 4.849E-2
3.566E-1
4.621E-1
 3 440
10 15846300-SuppTable4 Human Stomach Hofsli05 99genes RegulatedbyPACAP GeneSigDB 5.529E-4 4.849E-2
3.566E-1
4.849E-1
 2 92
11 15846300-SuppTable2 Human Stomach Hofsli05 101genes GeneSigDB 6.270E-4 4.999E-2
3.677E-1
5.499E-1
 2 98
Show 6 more annotations

14: Coexpression Atlas [Display Chart] 9 input genes in category / 1161 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 7 input genes in category / 52 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M3473 GCM SUPT4H1 Neighborhood of SUPT4H1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.765E-4 2.982E-2
1.353E-1
 3.518E-2 2 58
2 M1846 MODULE 220 Developmental processes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.147E-3 2.982E-2
1.353E-1
5.964E-2
 3 333
3 M12365 GCM RING1 Neighborhood of RING1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.411E-3 3.175E-2
1.441E-1
1.254E-1
 2 110
4 M2495 GCM HMGA2 Neighborhood of HMGA2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.957E-3 3.175E-2
1.441E-1
1.538E-1
 2 122
5 M2127 GCM FANCC Neighborhood of FANCC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.053E-3 3.175E-2
1.441E-1
1.588E-1
 2 124
6 M10197 MODULE 92 Secreted signaling molecules. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.378E-3 3.794E-2
1.722E-1
2.276E-1
 2 149
Show 1 more annotation

16: MicroRNA [Display Chart] 9 input genes in category / 586 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-588:PITA hsa-miR-588:PITA TOP PITA 6.061E-7 3.552E-4 2.469E-3 3.552E-4 3 141
2 hsa-miR-5579-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.302E-5 1.616E-3 1.123E-2 7.627E-3 2 44
3 hsa-miR-182:PITA hsa-miR-182:PITA TOP PITA 2.362E-5 1.616E-3 1.123E-2 1.384E-2 3 479
4 hsa-miR-32:PITA hsa-miR-32:PITA TOP PITA 2.377E-5 1.616E-3 1.123E-2 1.393E-2 3 480
5 hsa-miR-363:PITA hsa-miR-363:PITA TOP PITA 2.466E-5 1.616E-3 1.123E-2 1.445E-2 3 486
6 hsa-miR-25:PITA hsa-miR-25:PITA TOP PITA 2.482E-5 1.616E-3 1.123E-2 1.454E-2 3 487
7 hsa-miR-92a:PITA hsa-miR-92a:PITA TOP PITA 2.482E-5 1.616E-3 1.123E-2 1.454E-2 3 487
8 hsa-miR-367:PITA hsa-miR-367:PITA TOP PITA 2.482E-5 1.616E-3 1.123E-2 1.454E-2 3 487
9 hsa-miR-92b:PITA hsa-miR-92b:PITA TOP PITA 2.482E-5 1.616E-3 1.123E-2 1.454E-2 3 487
10 hsa-miR-9-3p:Functional MTI Functional MTI miRTarbase 7.483E-5 4.385E-3 3.048E-2 4.385E-2 2 105
11 hsa-miR-3978:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.135E-5 4.656E-3 3.236E-2
5.353E-2
 2 116
12 hsa-miR-206:Functional MTI Functional MTI miRTarbase 1.010E-4 4.656E-3 3.236E-2
5.921E-2
 2 122
13 hsa-miR-6132:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.112E-4 4.656E-3 3.236E-2
6.518E-2
 2 128
14 hsa-miR-6836-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.112E-4 4.656E-3 3.236E-2
6.518E-2
 2 128
15 hsa-miR-508-3p:PITA hsa-miR-508-3p:PITA TOP PITA 1.388E-4 5.407E-3 3.759E-2
8.134E-2
 2 143
16 hsa-miR-423-5p:TargetScan hsa-miR-423-5p TargetScan 1.673E-4 5.407E-3 3.759E-2
9.802E-2
 2 157
17 hsa-miR-937:mirSVR lowEffct hsa-miR-937:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 1.737E-4 5.407E-3 3.759E-2
1.018E-1
 2 160
18 hsa-miR-943:PITA hsa-miR-943:PITA TOP PITA 1.737E-4 5.407E-3 3.759E-2
1.018E-1
 2 160
19 hsa-miR-1274b:PITA hsa-miR-1274b:PITA TOP PITA 1.892E-4 5.407E-3 3.759E-2
1.109E-1
 2 167
20 hsa-miR-342-3p:PITA hsa-miR-342-3p:PITA TOP PITA 1.892E-4 5.407E-3 3.759E-2
1.109E-1
 2 167
21 hsa-miR-10a:PITA hsa-miR-10a:PITA TOP PITA 2.030E-4 5.407E-3 3.759E-2
1.190E-1
 2 173
22 hsa-miR-10b:PITA hsa-miR-10b:PITA TOP PITA 2.030E-4 5.407E-3 3.759E-2
1.190E-1
 2 173
23 hsa-miR-1228:PITA hsa-miR-1228:PITA TOP PITA 2.222E-4 5.605E-3 3.896E-2
1.302E-1
 2 181
24 hsa-miR-504-5p.1:TargetScan hsa-miR-504-5p.1 TargetScan 2.296E-4 5.605E-3 3.896E-2
1.345E-1
 2 184
25 hsa-miR-4651:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.499E-4 5.651E-3 3.928E-2
1.464E-1
 2 192
26 hsa-miR-608:Functional MTI Functional MTI miRTarbase 2.577E-4 5.651E-3 3.928E-2
1.510E-1
 2 195
27 hsa-miR-650:PITA hsa-miR-650:PITA TOP PITA 2.604E-4 5.651E-3 3.928E-2
1.526E-1
 2 196
28 hsa-miR-96-5p:Functional MTI Functional MTI miRTarbase 2.738E-4 5.670E-3 3.942E-2
1.604E-1
 2 201
29 hsa-miR-548e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.820E-4 5.670E-3 3.942E-2
1.652E-1
 2 204
30 hsa-miR-1229-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.903E-4 5.670E-3 3.942E-2
1.701E-1
 2 207
31 hsa-miR-297:PITA hsa-miR-297:PITA TOP PITA 3.705E-4 6.521E-3 4.533E-2
2.171E-1
 2 234
32 hsa-miR-505:PITA hsa-miR-505:PITA TOP PITA 3.961E-4 6.521E-3 4.533E-2
2.321E-1
 2 242
33 hsa-miR-371-5p:PITA hsa-miR-371-5p:PITA TOP PITA 3.994E-4 6.521E-3 4.533E-2
2.340E-1
 2 243
34 hsa-miR-10b-5p:TargetScan hsa-miR-10b-5p TargetScan 4.027E-4 6.521E-3 4.533E-2
2.360E-1
 2 244
35 hsa-miR-10a-5p:TargetScan hsa-miR-10a-5p TargetScan 4.027E-4 6.521E-3 4.533E-2
2.360E-1
 2 244
36 hsa-miR-659:PITA hsa-miR-659:PITA TOP PITA 4.192E-4 6.521E-3 4.533E-2
2.457E-1
 2 249
37 hsa-miR-1179:PITA hsa-miR-1179:PITA TOP PITA 4.327E-4 6.521E-3 4.533E-2
2.536E-1
 2 253
38 hsa-miR-1827:PITA hsa-miR-1827:PITA TOP PITA 4.603E-4 6.521E-3 4.533E-2
2.698E-1
 2 261
39 hsa-miR-891b:PITA hsa-miR-891b:PITA TOP PITA 4.852E-4 6.521E-3 4.533E-2
2.843E-1
 2 268
40 ACATTCC,MIR-1:MSigDB ACATTCC,MIR-1:MSigDB MSigDB 5.406E-4 6.521E-3 4.533E-2
3.168E-1
 2 283
41 ACATTCC,MIR-206:MSigDB ACATTCC,MIR-206:MSigDB MSigDB 5.406E-4 6.521E-3 4.533E-2
3.168E-1
 2 283
42 hsa-miR-365b-3p:TargetScan hsa-miR-365b-3p TargetScan 5.482E-4 6.521E-3 4.533E-2
3.213E-1
 2 285
43 hsa-miR-365a-3p:TargetScan hsa-miR-365a-3p TargetScan 5.482E-4 6.521E-3 4.533E-2
3.213E-1
 2 285
44 hsa-miR-4756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.521E-4 6.521E-3 4.533E-2
3.235E-1
 2 286
45 hsa-miR-1321:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.559E-4 6.521E-3 4.533E-2
3.258E-1
 2 287
46 GTGCAAT,MIR-367:MSigDB GTGCAAT,MIR-367:MSigDB MSigDB 5.636E-4 6.521E-3 4.533E-2
3.303E-1
 2 289
47 GTGCAAT,MIR-32:MSigDB GTGCAAT,MIR-32:MSigDB MSigDB 5.636E-4 6.521E-3 4.533E-2
3.303E-1
 2 289
48 GTGCAAT,MIR-92:MSigDB GTGCAAT,MIR-92:MSigDB MSigDB 5.636E-4 6.521E-3 4.533E-2
3.303E-1
 2 289
49 GTGCAAT,MIR-25:MSigDB GTGCAAT,MIR-25:MSigDB MSigDB 5.636E-4 6.521E-3 4.533E-2
3.303E-1
 2 289
50 GTGCAAT,MIR-363:MSigDB GTGCAAT,MIR-363:MSigDB MSigDB 5.636E-4 6.521E-3 4.533E-2
3.303E-1
 2 289
Show 45 more annotations

17: Drug [Display Chart] 9 input genes in category / 3221 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID006419759 K00077 Stitch 6.286E-11 2.025E-7 1.752E-6 2.025E-7 6 221
2 CID000480137 TAT-4 Stitch 8.455E-10 1.362E-6 1.179E-5 2.723E-6 3 6
3 ctd:C096822 PD 90780 CTD 1.380E-7 1.482E-4 1.282E-3 4.445E-4 2 2
4 CID000004819 pilocarpine- Stitch 2.024E-7 1.629E-4 1.410E-3 6.518E-4 4 147
5 CID000445227 N-Fg Stitch 3.265E-7 2.103E-4 1.820E-3 1.052E-3 3 37
6 CID000169313 3-(2-carboxyindol-3-yl)propionic acid Stitch 5.179E-7 2.383E-4 2.063E-3 1.668E-3 3 43
7 CID000126565 CEP-701 Stitch 5.179E-7 2.383E-4 2.063E-3 1.668E-3 3 43
8 CID000017429 FP-I Stitch 6.367E-7 2.563E-4 2.219E-3 2.051E-3 3 46
9 ctd:C040810 9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 CTD 8.277E-7 2.811E-4 2.433E-3 2.666E-3 2 4
10 CID000131613 MtT-S Stitch 8.726E-7 2.811E-4 2.433E-3 2.811E-3 3 51
11 CID000133005 CEP-1347 Stitch 1.360E-6 3.982E-4 3.447E-3 4.381E-3 3 59
12 CID000082686 cresyl violet acetate Stitch 1.505E-6 4.040E-4 3.496E-3 4.848E-3 3 61
13 CID000817373 5-phenylpyrimidine Stitch 2.069E-6 4.663E-4 4.036E-3 6.663E-3 2 6
14 ctd:D002248 Carbon Monoxide CTD 2.595E-6 4.663E-4 4.036E-3 8.358E-3 3 73
15 CID000090579 2,3-dihydroxybenzaldehyde Stitch 2.595E-6 4.663E-4 4.036E-3 8.358E-3 3 73
16 CID005289285 Reidispongiolide C Stitch 2.654E-6 4.663E-4 4.036E-3 8.547E-3 4 280
17 CID000001263 AC1L1B35 Stitch 2.704E-6 4.663E-4 4.036E-3 8.709E-3 3 74
18 ctd:D010862 Pilocarpine CTD 2.887E-6 4.663E-4 4.036E-3 9.298E-3 4 286
19 ctd:C424427 NEPP11 compound CTD 2.895E-6 4.663E-4 4.036E-3 9.326E-3 2 7
20 CID000077516 Koshland's Reagent II Stitch 2.895E-6 4.663E-4 4.036E-3 9.326E-3 2 7
21 ctd:D018170 Sumatriptan CTD 3.554E-6 5.451E-4 4.718E-3 1.145E-2 3 81
22 CID000013356 Triap Stitch 3.860E-6 5.555E-4 4.808E-3 1.243E-2 2 8
23 CID000000001 acetyl-L-carnitine Stitch 3.967E-6 5.555E-4 4.808E-3 1.278E-2 3 84
24 CID000003813 K 252 Stitch 4.565E-6 5.707E-4 4.940E-3 1.470E-2 3 88
25 ctd:C432165 pyrazolanthrone CTD 4.620E-6 5.707E-4 4.940E-3 1.488E-2 4 322
26 CID000211458 SCT-1 Stitch 4.961E-6 5.707E-4 4.940E-3 1.598E-2 2 9
27 ctd:C055778 panaxydol CTD 4.961E-6 5.707E-4 4.940E-3 1.598E-2 2 9
28 CID000292427 Val-Met Stitch 4.961E-6 5.707E-4 4.940E-3 1.598E-2 2 9
29 CID000003154 Cosopt Stitch 5.797E-6 6.439E-4 5.573E-3 1.867E-2 4 341
30 ctd:D001498 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester CTD 7.577E-6 8.135E-4 7.041E-3 2.440E-2 2 11
31 CID000006035 bromodeoxyuridine Stitch 8.530E-6 8.443E-4 7.307E-3 2.748E-2 4 376
32 CID005288002 C-X6 Stitch 9.090E-6 8.443E-4 7.307E-3 2.928E-2 2 12
33 CID000162083 Ac)5GP Stitch 9.090E-6 8.443E-4 7.307E-3 2.928E-2 2 12
34 ctd:D009288 Naproxen CTD 9.185E-6 8.443E-4 7.307E-3 2.958E-2 3 111
35 CID005288823 heptamolybdate Stitch 9.436E-6 8.443E-4 7.307E-3 3.039E-2 3 112
36 CID000005542 AC1L1KKT Stitch 9.436E-6 8.443E-4 7.307E-3 3.039E-2 3 112
37 CID005328127 PD166866 Stitch 1.074E-5 8.682E-4 7.514E-3 3.460E-2 2 13
38 ctd:D011189 Potassium Chloride CTD 1.076E-5 8.682E-4 7.514E-3 3.465E-2 3 117
39 CID005497107 G(M1 Stitch 1.076E-5 8.682E-4 7.514E-3 3.465E-2 3 117
40 ctd:C085911 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one CTD 1.089E-5 8.682E-4 7.514E-3 3.508E-2 4 400
41 ctd:C093973 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one CTD 1.111E-5 8.682E-4 7.514E-3 3.577E-2 4 402
42 ctd:D012110 Reserpine CTD 1.132E-5 8.682E-4 7.514E-3 3.646E-2 3 119
43 CID000001233 ibotenic acid Stitch 1.220E-5 8.968E-4 7.761E-3 3.929E-2 3 122
44 ctd:C060297 echinacoside CTD 1.253E-5 8.968E-4 7.761E-3 4.035E-2 2 14
45 CID000199656 ethylcholine mustard Stitch 1.253E-5 8.968E-4 7.761E-3 4.035E-2 2 14
46 CID000440805 2-amino-5-oxohexanoate Stitch 1.580E-5 1.107E-3 9.577E-3
5.090E-2
 3 133
47 ctd:D000069348 Quetiapine Fumarate CTD 1.651E-5 1.132E-3 9.795E-3
5.319E-2
 2 16
48 CID006398444 AC1O4QI2 Stitch 1.727E-5 1.159E-3 1.003E-2
5.563E-2
 3 137
49 ctd:D003871 Dermatan Sulfate CTD 1.871E-5 1.205E-3 1.043E-2
6.027E-2
 2 17
50 CID000004092 AC1L1HE7 Stitch 1.871E-5 1.205E-3 1.043E-2
6.027E-2
 2 17
Show 45 more annotations

18: Disease [Display Chart] 9 input genes in category / 787 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0027746 Nerve Degeneration DisGeNET Curated 3.502E-7 2.756E-4 1.997E-3 2.756E-4 4 120
2 C0027766 Nervous System Neoplasms DisGeNET Curated 1.551E-6 4.661E-4 3.378E-3 1.221E-3 3 44
3 C0150055 Chronic pain DisGeNET Curated 1.777E-6 4.661E-4 3.378E-3 1.398E-3 3 46
4 C0020074 HSAN Type IV DisGeNET Curated 4.108E-6 5.764E-4 4.176E-3 3.233E-3 2 6
5 C0457949 Chronic low back pain DisGeNET BeFree 4.108E-6 5.764E-4 4.176E-3 3.233E-3 2 6
6 C0233794 Memory impairment DisGeNET Curated 4.394E-6 5.764E-4 4.176E-3 3.458E-3 4 226
7 C0751295 Memory Loss DisGeNET Curated 8.489E-6 9.544E-4 6.915E-3 6.681E-3 3 77
8 C0342418 Hypothalamic hamartomas DisGeNET Curated 9.851E-6 9.691E-4 7.022E-3 7.753E-3 2 9
9 C0424290 Compulsive hoarding DisGeNET Curated 1.231E-5 1.030E-3 7.464E-3 9.688E-3 2 10
10 C1368683 Epithelioma DisGeNET BeFree 1.313E-5 1.030E-3 7.464E-3 1.033E-2 4 298
11 C0236642 Pick Disease of the Brain DisGeNET Curated 1.499E-5 1.030E-3 7.464E-3 1.180E-2 3 93
12 C0525045 Mood Disorders DisGeNET Curated 1.594E-5 1.030E-3 7.464E-3 1.254E-2 4 313
13 C0027796 Neuralgia DisGeNET Curated 1.701E-5 1.030E-3 7.464E-3 1.339E-2 3 97
14 C0393570 Corticobasal degeneration DisGeNET BeFree 2.132E-5 1.198E-3 8.684E-3 1.678E-2 2 13
15 C2748208 Executive dysfunction DisGeNET BeFree 2.487E-5 1.213E-3 8.786E-3 1.957E-2 2 14
16 C0020429 Hyperalgesia DisGeNET Curated 2.550E-5 1.213E-3 8.786E-3 2.007E-2 3 111
17 C0206663 Neuroectodermal Tumor, Primitive DisGeNET Curated 2.619E-5 1.213E-3 8.786E-3 2.061E-2 3 112
18 C0014549 Tonic-Clonic Epilepsy DisGeNET Curated 2.868E-5 1.254E-3 9.087E-3 2.257E-2 2 15
19 C0038220 Status Epilepticus DisGeNET Curated 3.383E-5 1.333E-3 9.658E-3 2.663E-2 3 122
20 C3887678 CPNET DisGeNET BeFree 3.713E-5 1.333E-3 9.658E-3 2.922E-2 2 17
21 C0024031 Low Back Pain DisGeNET Curated 3.713E-5 1.333E-3 9.658E-3 2.922E-2 2 17
22 C0949664 Tauopathies DisGeNET Curated 3.726E-5 1.333E-3 9.658E-3 2.932E-2 3 126
23 C0013080 Down Syndrome DisGeNET Curated 5.294E-5 1.803E-3 1.306E-2 4.167E-2 4 425
24 C0024897 Mastocytoma DisGeNET BeFree 5.727E-5 1.803E-3 1.306E-2 4.507E-2 2 21
25 C2242987 Benign Mastocytoma DisGeNET BeFree 5.727E-5 1.803E-3 1.306E-2 4.507E-2 2 21
26 C0085632 Apathy DisGeNET Curated 6.895E-5 2.010E-3 1.456E-2
5.427E-2
 2 23
27 C1318973 Staphylococcus aureus infection DisGeNET BeFree 6.895E-5 2.010E-3 1.456E-2
5.427E-2
 2 23
28 C0030193 Pain DisGeNET Curated 7.971E-5 2.240E-3 1.623E-2
6.273E-2
 4 472
29 C0334664 Mast Cell Neoplasm DisGeNET BeFree 8.850E-5 2.402E-3 1.740E-2
6.965E-2
 2 26
30 C0220603 childhood brain tumor DisGeNET BeFree 9.555E-5 2.507E-3 1.816E-2
7.520E-2
 2 27
31 C0010692 Cystitis DisGeNET Curated 1.183E-4 3.004E-3 2.177E-2
9.312E-2
 2 30
32 C0085648 Synovial Cyst DisGeNET BeFree 1.517E-4 3.724E-3 2.699E-2
1.194E-1
 3 202
33 C1258666 Myxoid cyst DisGeNET BeFree 1.562E-4 3.724E-3 2.699E-2
1.229E-1
 3 204
34 C0017661 IGA Glomerulonephritis DisGeNET Curated 1.874E-4 4.339E-3 3.144E-2
1.475E-1
 3 217
35 C0236663 Alcohol withdrawal syndrome DisGeNET Curated 2.115E-4 4.757E-3 3.447E-2
1.665E-1
 2 40
36 C0206718 Ganglioneuroblastoma DisGeNET Curated 2.334E-4 5.044E-3 3.655E-2
1.837E-1
 2 42
37 C2936349 Plaque, Amyloid DisGeNET Curated 2.371E-4 5.044E-3 3.655E-2
1.866E-1
 3 235
38 C1290375 Mesothelioma (malignant, clinical disorder) (disorder) DisGeNET BeFree 2.947E-4 5.828E-3 4.223E-2
2.319E-1
 3 253
39 C0002622 Amnesia DisGeNET Curated 3.447E-4 5.828E-3 4.223E-2
2.713E-1
 2 51
40 C0442874 Neuropathy DisGeNET Curated 3.528E-4 5.828E-3 4.223E-2
2.777E-1
 3 269
41 C0031117 Peripheral Neuropathy DisGeNET Curated 3.845E-4 5.828E-3 4.223E-2
3.026E-1
 3 277
42 C0019337 Heroin Dependence DisGeNET Curated 4.460E-4 5.828E-3 4.223E-2
3.510E-1
 2 58
43 C0024899 Mastocytosis DisGeNET Curated 4.933E-4 5.828E-3 4.223E-2
3.882E-1
 2 61
44 C3811918 GRN-related frontotemporal dementia DisGeNET BeFree 5.262E-4 5.828E-3 4.223E-2
4.141E-1
 2 63
45 C1839259 Bulbo-Spinal Atrophy, X-Linked DisGeNET Curated 5.262E-4 5.828E-3 4.223E-2
4.141E-1
 2 63
46 C0333463 Senile Plaques DisGeNET BeFree 5.397E-4 5.828E-3 4.223E-2
4.248E-1
 3 311
47 C0038868 Progressive supranuclear palsy DisGeNET Curated 5.430E-4 5.828E-3 4.223E-2
4.273E-1
 2 64
48 C0011265 Presenile dementia DisGeNET BeFree 5.551E-4 5.828E-3 4.223E-2
4.368E-1
 3 314
49 C4225326 FRONTOTEMPORAL DEMENTIA AND/OR AMYOTROPHIC LATERAL SCLEROSIS 3 DisGeNET Curated 5.554E-4 5.828E-3 4.223E-2
4.371E-1
 1 1
50 C0346363 Nevus of conjunctiva DisGeNET BeFree 5.554E-4 5.828E-3 4.223E-2
4.371E-1
 1 1
Show 45 more annotations