Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc400_5, positive side

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1: GO: Molecular Function [Display Chart] 5 input genes in category / 40 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0031386 protein tag 5.169E-10 2.068E-8 8.847E-8 2.068E-8 3 8
2 GO:0019789 SUMO transferase activity 1.719E-5 3.165E-4 1.354E-3 6.875E-4 2 25
3 GO:0031625 ubiquitin protein ligase binding 3.030E-5 3.165E-4 1.354E-3 1.212E-3 3 273
4 GO:0044389 ubiquitin-like protein ligase binding 3.165E-5 3.165E-4 1.354E-3 1.266E-3 3 277
5 GO:0000703 oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity 5.358E-4 4.287E-3 1.834E-2 2.143E-2 1 2
6 GO:0000702 oxidized base lesion DNA N-glycosylase activity 1.071E-3 7.143E-3 3.056E-2 4.286E-2 1 4
7 GO:0050897 cobalt ion binding 2.142E-3 8.449E-3 3.615E-2
8.568E-2
 1 8
8 GO:0070635 nicotinamide riboside hydrolase activity 2.944E-3 8.449E-3 3.615E-2
1.178E-1
 1 11
9 GO:0070694 deoxyribonucleoside 5'-monophosphate N-glycosidase activity 2.944E-3 8.449E-3 3.615E-2
1.178E-1
 1 11
10 GO:0070636 nicotinic acid riboside hydrolase activity 2.944E-3 8.449E-3 3.615E-2
1.178E-1
 1 11
11 GO:0017065 single-strand selective uracil DNA N-glycosylase activity 2.944E-3 8.449E-3 3.615E-2
1.178E-1
 1 11
12 GO:0043733 DNA-3-methylbase glycosylase activity 3.211E-3 8.449E-3 3.615E-2
1.285E-1
 1 12
13 GO:0003905 alkylbase DNA N-glycosylase activity 3.211E-3 8.449E-3 3.615E-2
1.285E-1
 1 12
14 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity 3.211E-3 8.449E-3 3.615E-2
1.285E-1
 1 12
15 GO:0000700 mismatch base pair DNA N-glycosylase activity 3.479E-3 8.449E-3 3.615E-2
1.391E-1
 1 13
16 GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity 3.746E-3 8.449E-3 3.615E-2
1.498E-1
 1 14
17 GO:0097506 deaminated base DNA N-glycosylase activity 4.013E-3 8.449E-3 3.615E-2
1.605E-1
 1 15
18 GO:0004844 uracil DNA N-glycosylase activity 4.013E-3 8.449E-3 3.615E-2
1.605E-1
 1 15
19 GO:0032183 SUMO binding 4.013E-3 8.449E-3 3.615E-2
1.605E-1
 1 15
20 GO:0019104 DNA N-glycosylase activity 4.814E-3 9.628E-3 4.119E-2
1.926E-1
 1 18
21 GO:0019787 ubiquitin-like protein transferase activity 5.315E-3 1.012E-2 4.331E-2
2.126E-1
 2 441
22 GO:0046965 retinoid X receptor binding 5.881E-3 1.069E-2 4.575E-2
2.353E-1
 1 22
23 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 6.681E-3 1.162E-2 4.971E-2
2.673E-1
 1 25
24 GO:0015459 potassium channel regulator activity 1.280E-2 2.133E-2
9.125E-2
5.119E-1
 1 48
25 GO:0042974 retinoic acid receptor binding 1.359E-2 2.175E-2
9.305E-2
5.437E-1
 1 51
26 GO:0046332 SMAD binding 2.046E-2 3.148E-2
1.347E-1
8.186E-1
 1 77
27 GO:0016835 carbon-oxygen lyase activity 2.310E-2 3.422E-2
1.464E-1
9.239E-1
 1 87
28 GO:0004520 endodeoxyribonuclease activity 2.494E-2 3.562E-2
1.524E-1
9.975E-1
 1 94
29 GO:0003697 single-stranded DNA binding 2.756E-2 3.801E-2
1.626E-1
1.000E0
 1 104
30 GO:0004536 deoxyribonuclease activity 2.887E-2 3.849E-2
1.647E-1
1.000E0
 1 109
31 GO:0032182 ubiquitin-like protein binding 3.357E-2 4.196E-2
1.795E-1
1.000E0
 1 127
32 GO:0044325 ion channel binding 3.357E-2 4.196E-2
1.795E-1
1.000E0
 1 127
33 GO:0016247 channel regulator activity 3.670E-2 4.448E-2
1.903E-1
1.000E0
 1 139
34 GO:0035257 nuclear hormone receptor binding 4.240E-2 4.989E-2
2.134E-1
1.000E0
 1 161
Show 29 more annotations

2: GO: Biological Process [Display Chart] 5 input genes in category / 418 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016925 protein sumoylation 1.521E-8 6.357E-6 4.205E-5 6.357E-6 4 140
2 GO:0070911 global genome nucleotide-excision repair 4.598E-8 9.609E-6 6.355E-5 1.922E-5 3 32
3 GO:1903050 regulation of proteolysis involved in cellular protein catabolic process 2.043E-7 2.846E-5 1.882E-4 8.539E-5 4 267
4 GO:1903362 regulation of cellular protein catabolic process 2.729E-7 2.852E-5 1.886E-4 1.141E-4 4 287
5 GO:0045862 positive regulation of proteolysis 8.485E-7 6.024E-5 3.984E-4 3.547E-4 4 381
6 GO:0030578 PML body organization 8.647E-7 6.024E-5 3.984E-4 3.614E-4 2 6
7 GO:0042176 regulation of protein catabolic process 1.183E-6 6.927E-5 4.582E-4 4.944E-4 4 414
8 GO:0018205 peptidyl-lysine modification 1.326E-6 6.927E-5 4.582E-4 5.542E-4 4 426
9 GO:0006289 nucleotide-excision repair 2.520E-6 1.084E-4 7.168E-4 1.054E-3 3 119
10 GO:0030575 nuclear body organization 2.593E-6 1.084E-4 7.168E-4 1.084E-3 2 10
11 GO:1903052 positive regulation of proteolysis involved in cellular protein catabolic process 8.755E-6 3.327E-4 2.200E-3 3.660E-3 3 180
12 GO:1903364 positive regulation of cellular protein catabolic process 1.096E-5 3.818E-4 2.525E-3 4.582E-3 3 194
13 GO:0045732 positive regulation of protein catabolic process 2.885E-5 9.276E-4 6.135E-3 1.206E-2 3 268
14 GO:1903320 regulation of protein modification by small protein conjugation or removal 3.652E-5 1.090E-3 7.211E-3 1.526E-2 3 290
15 GO:0031331 positive regulation of cellular catabolic process 6.510E-5 1.814E-3 1.200E-2 2.721E-2 3 352
16 GO:0034504 protein localization to nucleus 8.901E-5 2.222E-3 1.470E-2 3.721E-2 3 391
17 GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 9.037E-5 2.222E-3 1.470E-2 3.778E-2 3 393
18 GO:0009896 positive regulation of catabolic process 1.055E-4 2.450E-3 1.620E-2 4.410E-2 3 414
19 GO:0010498 proteasomal protein catabolic process 1.117E-4 2.457E-3 1.625E-2 4.668E-2 3 422
20 GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 1.946E-4 4.062E-3 2.686E-2
8.132E-2
 2 83
21 GO:0060333 interferon-gamma-mediated signaling pathway 2.041E-4 4.062E-3 2.686E-2
8.529E-2
 2 85
22 GO:1901800 positive regulation of proteasomal protein catabolic process 2.658E-4 4.676E-3 3.093E-2
1.111E-1
 2 97
23 GO:0043556 regulation of translation in response to oxidative stress 2.685E-4 4.676E-3 3.093E-2
1.122E-1
 1 1
24 GO:0032938 negative regulation of translation in response to oxidative stress 2.685E-4 4.676E-3 3.093E-2
1.122E-1
 1 1
25 GO:2000058 regulation of ubiquitin-dependent protein catabolic process 2.997E-4 5.010E-3 3.314E-2
1.253E-1
 2 103
26 GO:0090204 protein localization to nuclear pore 5.369E-4 8.490E-3
5.615E-2
2.244E-1
 1 2
27 GO:0071346 cellular response to interferon-gamma 5.529E-4 8.490E-3
5.615E-2
2.311E-1
 2 140
28 GO:0050821 protein stabilization 5.687E-4 8.490E-3
5.615E-2
2.377E-1
 2 142
29 GO:0006997 nucleus organization 6.176E-4 8.901E-3
5.887E-2
2.581E-1
 2 148
30 GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 6.684E-4 9.313E-3
6.159E-2
2.794E-1
 2 154
31 GO:0034341 response to interferon-gamma 7.483E-4 1.009E-2
6.674E-2
3.128E-1
 2 163
32 GO:0061136 regulation of proteasomal protein catabolic process 1.004E-3 1.312E-2
8.675E-2
4.197E-1
 2 189
33 GO:1901896 positive regulation of calcium-transporting ATPase activity 1.074E-3 1.327E-2
8.776E-2
4.488E-1
 1 4
34 GO:0006302 double-strand break repair 1.079E-3 1.327E-2
8.776E-2
4.511E-1
 2 196
35 GO:1903322 positive regulation of protein modification by small protein conjugation or removal 1.191E-3 1.368E-2
9.048E-2
4.979E-1
 2 206
36 GO:0060058 positive regulation of apoptotic process involved in mammary gland involution 1.342E-3 1.368E-2
9.048E-2
5.609E-1
 1 5
37 GO:0060057 apoptotic process involved in mammary gland involution 1.342E-3 1.368E-2
9.048E-2
5.609E-1
 1 5
38 GO:1904747 positive regulation of apoptotic process involved in development 1.342E-3 1.368E-2
9.048E-2
5.609E-1
 1 5
39 GO:1902339 positive regulation of apoptotic process involved in morphogenesis 1.342E-3 1.368E-2
9.048E-2
5.609E-1
 1 5
40 GO:1903519 regulation of mammary gland involution 1.342E-3 1.368E-2
9.048E-2
5.609E-1
 1 5
41 GO:1903521 positive regulation of mammary gland involution 1.342E-3 1.368E-2
9.048E-2
5.609E-1
 1 5
42 GO:0031647 regulation of protein stability 1.572E-3 1.496E-2
9.891E-2
6.573E-1
 2 237
43 GO:0007182 common-partner SMAD protein phosphorylation 1.610E-3 1.496E-2
9.891E-2
6.730E-1
 1 6
44 GO:0090435 protein localization to nuclear envelope 1.610E-3 1.496E-2
9.891E-2
6.730E-1
 1 6
45 GO:0045345 positive regulation of MHC class I biosynthetic process 1.610E-3 1.496E-2
9.891E-2
6.730E-1
 1 6
46 GO:0051924 regulation of calcium ion transport 1.652E-3 1.501E-2
9.930E-2
6.906E-1
 2 243
47 GO:0050713 negative regulation of interleukin-1 beta secretion 1.878E-3 1.539E-2
1.018E-1
7.851E-1
 1 7
48 GO:0045759 negative regulation of action potential 1.878E-3 1.539E-2
1.018E-1
7.851E-1
 1 7
49 GO:0045343 regulation of MHC class I biosynthetic process 1.878E-3 1.539E-2
1.018E-1
7.851E-1
 1 7
50 GO:1901894 regulation of calcium-transporting ATPase activity 1.878E-3 1.539E-2
1.018E-1
7.851E-1
 1 7
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 5 input genes in category / 32 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016605 PML body 3.410E-9 1.091E-7 4.428E-7 1.091E-7 4 99
2 GO:0016604 nuclear body 6.444E-7 1.031E-5 4.184E-5 2.062E-5 4 364
3 GO:0042406 extrinsic component of endoplasmic reticulum membrane 1.311E-3 1.398E-2
5.676E-2
 4.195E-2 1 5
4 GO:0031965 nuclear membrane 2.238E-3 1.510E-2
6.127E-2
7.161E-2
 2 290
5 GO:0001650 fibrillar center 2.359E-3 1.510E-2
6.127E-2
7.548E-2
 1 9
6 GO:0098687 chromosomal region 3.133E-3 1.671E-2
6.781E-2
1.002E-1
 2 344
7 GO:0001741 XY body 4.452E-3 2.035E-2
8.260E-2
1.425E-1
 1 17
8 GO:0005635 nuclear envelope 5.397E-3 2.159E-2
8.762E-2
1.727E-1
 2 454
9 GO:0000803 sex chromosome 8.367E-3 2.761E-2
1.120E-1
2.677E-1
 1 32
10 GO:0031312 extrinsic component of organelle membrane 8.627E-3 2.761E-2
1.120E-1
2.761E-1
 1 33
Show 5 more annotations

4: Human Phenotype [Display Chart] 2 input genes in category / 12 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0100334 Unilateral cleft palate 4.249E-4 5.099E-3 1.582E-2 5.099E-3 1 1
2 HP:0100333 Unilateral cleft lip 2.972E-3 1.019E-2 3.162E-2 3.567E-2 1 7
3 HP:0100331 Unilateral cleft lip/palate 2.972E-3 1.019E-2 3.162E-2 3.567E-2 1 7
4 HP:0100338 Non-midline cleft palate 3.397E-3 1.019E-2 3.162E-2 4.076E-2 1 8
5 HP:0012135 Abnormal granulocytopoietic cell morphology 5.093E-3 1.222E-2 3.793E-2
6.111E-2
 1 12
6 HP:0100335 Non-midline cleft lip 1.186E-2 2.034E-2
6.311E-2
1.424E-1
 1 28
7 HP:0100332 Non-midline cleft lip/palate 1.186E-2 2.034E-2
6.311E-2
1.424E-1
 1 28
8 HP:0004836 Acute promyelocytic leukemia 2.198E-2 3.296E-2
1.023E-1
2.637E-1
 1 52
Show 3 more annotations

5: Mouse Phenotype [Display Chart] 5 input genes in category / 65 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0008886 abnormal PML bodies 1.865E-7 1.213E-5 5.771E-5 1.213E-5 2 2
2 MP:0011109 lethality throughout fetal growth and development, incomplete penetrance 1.358E-4 4.412E-3 2.100E-2 8.824E-3 3 251
3 MP:0008799 oblique facial cleft 4.829E-4 1.046E-2 4.979E-2 3.139E-2 1 1
4 MP:0008058 abnormal DNA repair 1.412E-3 2.294E-2
1.092E-1
9.176E-2
 2 125
5 MP:0009656 delayed chorioallantoic fusion 2.894E-3 2.836E-2
1.350E-1
1.881E-1
 1 6
6 MP:0003111 abnormal cell nucleus morphology 3.330E-3 2.836E-2
1.350E-1
2.165E-1
 2 193
7 MP:0004049 increased acute promyelocytic leukemia incidence 4.339E-3 2.836E-2
1.350E-1
2.820E-1
 1 9
8 MP:0009797 abnormal mismatch repair 4.339E-3 2.836E-2
1.350E-1
2.820E-1
 1 9
9 MP:0009796 abnormal base-excision repair 4.820E-3 2.836E-2
1.350E-1
3.133E-1
 1 10
10 MP:0006323 abnormal extraembryonic mesoderm development 5.301E-3 2.836E-2
1.350E-1
3.446E-1
 1 11
11 MP:0008942 abnormal induced cell death 5.751E-3 2.836E-2
1.350E-1
3.738E-1
 2 255
12 MP:0012431 increased lymphoma incidence 5.751E-3 2.836E-2
1.350E-1
3.738E-1
 2 255
13 MP:0009703 decreased birth body size 5.974E-3 2.836E-2
1.350E-1
3.883E-1
 2 260
14 MP:0009701 abnormal birth body size 6.109E-3 2.836E-2
1.350E-1
3.971E-1
 2 263
15 MP:0003794 delayed somite formation 7.223E-3 3.130E-2
1.490E-1
4.695E-1
 1 15
16 MP:0010296 increased hemolymphoid system tumor incidence 8.153E-3 3.312E-2
1.576E-1
5.299E-1
 2 305
17 MP:0012082 delayed heart development 9.142E-3 3.475E-2
1.654E-1
5.943E-1
 1 19
18 MP:0003701 elevated level of mitotic sister chromatid exchange 9.622E-3 3.475E-2
1.654E-1
6.254E-1
 1 20
19 MP:0005030 absent amnion 1.249E-2 4.274E-2
2.034E-1
8.121E-1
 1 26
Show 14 more annotations

6: Domain [Display Chart] 5 input genes in category / 26 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR033950 Sumo InterPro 3.650E-11 7.908E-10 3.048E-9 9.490E-10 3 4
2 PF11976 Rad60-SLD Pfam 9.124E-11 7.908E-10 3.048E-9 2.372E-9 3 5
3 IPR022617 Rad60/SUMO-like dom InterPro 9.124E-11 7.908E-10 3.048E-9 2.372E-9 3 5
4 SM00213 UBQ SMART 1.123E-7 7.297E-7 2.812E-6 2.919E-6 3 43
5 PF00240 ubiquitin Pfam 1.475E-7 7.407E-7 2.855E-6 3.834E-6 3 47
6 IPR027218 SUMO chordates InterPro 1.709E-7 7.407E-7 2.855E-6 4.444E-6 2 3
7 PS50053 UBIQUITIN 2 PROSITE 2.254E-7 8.373E-7 3.227E-6 5.861E-6 3 54
8 IPR000626 Ubiquitin dom InterPro 2.803E-7 9.111E-7 3.512E-6 7.289E-6 3 58
9 IPR029071 Ubiquitin-rel dom InterPro 9.186E-6 2.654E-5 1.023E-4 2.388E-4 3 184
10 IPR021978 DUF3583 InterPro 2.669E-4 6.308E-4 2.431E-3 6.939E-3 1 1
11 PF12126 DUF3583 Pfam 2.669E-4 6.308E-4 2.431E-3 6.939E-3 1 1
12 IPR005122 Uracil-DNA glycosylase-like InterPro 8.005E-4 1.487E-3 5.730E-3 2.081E-2 1 3
13 PF03167 UDG Pfam 8.005E-4 1.487E-3 5.730E-3 2.081E-2 1 3
14 3.40.470.10 - Gene3D 8.005E-4 1.487E-3 5.730E-3 2.081E-2 1 3
15 SM00336 BBOX SMART 1.828E-2 3.096E-2
1.193E-1
4.753E-1
 1 69
16 PF00643 zf-B box Pfam 1.907E-2 3.096E-2
1.193E-1
4.958E-1
 1 72
17 PS50119 ZF BBOX PROSITE 2.117E-2 3.096E-2
1.193E-1
5.504E-1
 1 80
18 IPR000315 Znf B-box InterPro 2.143E-2 3.096E-2
1.193E-1
5.573E-1
 1 81
Show 13 more annotations

7: Pathway [Display Chart] 5 input genes in category / 61 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1268741 SUMO is conjugated to E1 (UBA2:SAE1) BioSystems: REACTOME 3.109E-10 1.896E-8 8.906E-8 1.897E-8 3 5
2 1268740 SUMO is proteolytically processed BioSystems: REACTOME 6.218E-10 1.896E-8 8.906E-8 3.793E-8 3 6
3 1268742 SUMO is transferred from E1 to E2 (UBE2I, UBC9) BioSystems: REACTOME 1.088E-9 2.212E-8 1.039E-7 6.636E-8 3 7
4 1268739 Processing and activation of SUMO BioSystems: REACTOME 3.729E-9 5.686E-8 2.670E-7 2.275E-7 3 10
5 1268744 SUMOylation of DNA damage response and repair proteins BioSystems: REACTOME 7.094E-9 7.596E-8 3.567E-7 4.327E-7 4 78
6 P00059 p53 pathway PantherDB 7.472E-9 7.596E-8 3.567E-7 4.558E-7 4 79
7 1339110 SUMOylation of transcription factors BioSystems: REACTOME 2.111E-8 1.741E-7 8.175E-7 1.288E-6 3 17
8 1268743 SUMO E3 ligases SUMOylate target proteins BioSystems: REACTOME 2.283E-8 1.741E-7 8.175E-7 1.393E-6 4 104
9 1268738 SUMOylation BioSystems: REACTOME 2.865E-8 1.942E-7 9.120E-7 1.748E-6 4 110
10 1309114 Formation of Incision Complex in GG-NER BioSystems: REACTOME 3.819E-7 2.330E-6 1.094E-5 2.330E-5 3 43
11 1339113 SUMOylation of DNA replication proteins BioSystems: REACTOME 4.696E-7 2.604E-6 1.223E-5 2.865E-5 3 46
12 1270350 DNA Repair BioSystems: REACTOME 2.073E-6 1.054E-5 4.949E-5 1.264E-4 4 319
13 1309112 Global Genome Nucleotide Excision Repair (GG-NER) BioSystems: REACTOME 3.041E-6 1.427E-5 6.702E-5 1.855E-4 3 85
14 1309111 Nucleotide Excision Repair BioSystems: REACTOME 6.995E-6 3.048E-5 1.431E-4 4.267E-4 3 112
15 1474302 Fluid shear stress and atherosclerosis BioSystems: KEGG 1.429E-5 5.810E-5 2.728E-4 8.715E-4 3 142
16 M4891 Regulation of transcriptional activity by PML MSigDB C2 BIOCARTA (v6.0) 1.751E-5 6.675E-5 3.135E-4 1.068E-3 2 17
17 177876 RNA transport BioSystems: KEGG 2.495E-5 8.953E-5 4.205E-4 1.522E-3 3 171
18 1339112 SUMOylation of RNA binding proteins BioSystems: REACTOME 1.445E-4 4.896E-4 2.299E-3 8.814E-3 2 48
19 1269314 Interferon gamma signaling BioSystems: REACTOME 5.557E-4 1.784E-3 8.379E-3 3.390E-2 2 94
20 1309101 Processing of DNA double-strand break ends BioSystems: REACTOME 6.163E-4 1.880E-3 8.827E-3 3.759E-2 2 99
21 1309100 HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) BioSystems: REACTOME 1.126E-3 3.257E-3 1.529E-2
6.867E-2
 2 134
22 PW:0000416 sentrinization Pathway Ontology 1.204E-3 3.257E-3 1.529E-2
7.347E-2
 1 3
23 1309099 Homology Directed Repair BioSystems: REACTOME 1.228E-3 3.257E-3 1.529E-2
7.491E-2
 2 140
24 1339111 SUMOylation of chromatin organization proteins BioSystems: REACTOME 1.606E-3 4.081E-3 1.917E-2
9.794E-2
 1 4
25 1309095 DNA Double-Strand Break Repair BioSystems: REACTOME 1.783E-3 4.351E-3 2.043E-2
1.088E-1
 2 169
26 1269311 Interferon Signaling BioSystems: REACTOME 2.536E-3 5.951E-3 2.795E-2
1.547E-1
 2 202
27 1270357 Recognition and association of DNA glycosylase with site containing an affected pyrimidine BioSystems: REACTOME 3.209E-3 6.750E-3 3.170E-2
1.958E-1
 1 8
28 1270358 Cleavage of the damaged pyrimidine BioSystems: REACTOME 3.209E-3 6.750E-3 3.170E-2
1.958E-1
 1 8
29 1270356 Depyrimidination BioSystems: REACTOME 3.209E-3 6.750E-3 3.170E-2
1.958E-1
 1 8
30 1270360 Displacement of DNA glycosylase by APEX1 BioSystems: REACTOME 3.610E-3 7.340E-3 3.447E-2
2.202E-1
 1 9
31 1270352 Base-Excision Repair, AP Site Formation BioSystems: REACTOME 4.010E-3 7.645E-3 3.590E-2
2.446E-1
 1 10
32 1427845 Negative regulation of activity of TFAP2 (AP-2) family transcription factors BioSystems: REACTOME 4.010E-3 7.645E-3 3.590E-2
2.446E-1
 1 10
33 138029 Sumoylation by RanBP2 regulates transcriptional repression BioSystems: Pathway Interaction Database 4.411E-3 8.153E-3 3.829E-2
2.690E-1
 1 11
34 M13917 Role of Parkin in the Ubiquitin-Proteasomal Pathway MSigDB C2 BIOCARTA (v6.0) 4.811E-3 8.631E-3 4.053E-2
2.935E-1
 1 12
35 1269315 Regulation of IFNG signaling BioSystems: REACTOME 5.611E-3 9.779E-3 4.592E-2
3.423E-1
 1 14
36 1383083 Regulation of TP53 Activity through Acetylation BioSystems: REACTOME 1.239E-2 2.099E-2
9.859E-2
7.558E-1
 1 31
37 83043 Base excision repair BioSystems: KEGG 1.319E-2 2.174E-2
1.021E-1
8.043E-1
 1 33
38 138062 Signaling events mediated by HDAC Class II BioSystems: Pathway Interaction Database 1.358E-2 2.180E-2
1.024E-1
8.285E-1
 1 34
39 1270359 Resolution of Abasic Sites (AP sites) BioSystems: REACTOME 1.477E-2 2.253E-2
1.058E-1
9.012E-1
 1 37
40 1270351 Base Excision Repair BioSystems: REACTOME 1.477E-2 2.253E-2
1.058E-1
9.012E-1
 1 37
41 1427839 Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors BioSystems: REACTOME 1.596E-2 2.375E-2
1.115E-1
9.738E-1
 1 40
42 138024 TGF-beta receptor signaling BioSystems: Pathway Interaction Database 2.032E-2 2.951E-2
1.386E-1
1.000E0
 1 51
43 83117 Acute myeloid leukemia BioSystems: KEGG 2.190E-2 3.106E-2
1.459E-1
1.000E0
 1 55
44 138001 mTOR signaling pathway BioSystems: Pathway Interaction Database 2.426E-2 3.364E-2
1.580E-1
1.000E0
 1 61
45 137997 Signaling events mediated by HDAC Class I BioSystems: Pathway Interaction Database 2.623E-2 3.556E-2
1.670E-1
1.000E0
 1 66
46 1309110 Nonhomologous End-Joining (NHEJ) BioSystems: REACTOME 2.780E-2 3.687E-2
1.731E-1
1.000E0
 1 70
47 1309098 Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks BioSystems: REACTOME 3.016E-2 3.882E-2
1.823E-1
1.000E0
 1 76
48 1309096 DNA Double Strand Break Response BioSystems: REACTOME 3.055E-2 3.882E-2
1.823E-1
1.000E0
 1 77
49 138014 Glucocorticoid receptor regulatory network BioSystems: Pathway Interaction Database 3.251E-2 4.047E-2
1.900E-1
1.000E0
 1 82
50 1269754 G2/M DNA damage checkpoint BioSystems: REACTOME 3.797E-2 4.632E-2
2.175E-1
1.000E0
 1 96
Show 45 more annotations

8: Pubmed [Display Chart] 5 input genes in category / 1328 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 9452416 Covalent modification of PML by the sentrin family of ubiquitin-like proteins. Pubmed 2.820E-16 1.873E-13 1.455E-12 3.745E-13 4 5
2 19033381 Loss of SUMO1 in mice affects RanGAP1 localization and formation of PML nuclear bodies, but is not lethal as it can be compensated by SUMO2 or SUMO3. Pubmed 2.820E-16 1.873E-13 1.455E-12 3.745E-13 4 5
3 17000875 SUSP1 antagonizes formation of highly SUMO2/3-conjugated species. Pubmed 8.460E-16 2.809E-13 2.182E-12 1.124E-12 4 6
4 21145359 Control of nuclear HIPK2 localization and function by a SUMO interaction motif. Pubmed 8.460E-16 2.809E-13 2.182E-12 1.124E-12 4 6
5 21779164 SUMO pathway dependent recruitment of cellular repressors to herpes simplex virus type 1 genomes. Pubmed 1.974E-15 5.243E-13 4.073E-12 2.622E-12 4 7
6 24637324 Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins. Pubmed 7.106E-15 1.573E-12 1.222E-11 9.437E-12 4 9
7 16608850 Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3. Pubmed 1.184E-14 2.247E-12 1.746E-11 1.573E-11 4 10
8 23530056 Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation. Pubmed 4.032E-14 6.693E-12 5.200E-11 5.355E-11 4 13
9 9119407 SMT3A, a human homologue of the S. cerevisiae SMT3 gene, maps to chromosome 21qter and defines a novel gene family. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
10 25617419 mRNA expression analysis of the SUMO pathway genes in the adult mouse retina. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
11 26223657 Small Ubiquitin-like Modifier Alters IFN Response. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
12 18694876 Small ubiquitin-related modifier (SUMO)-1, SUMO-2/3 and SUMOylation are involved with centromeric heterochromatin of chromosomes 9 and 1 and proteins of the synaptonemal complex during meiosis in men. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
13 23077236 Localization and identification of sumoylated proteins in human sperm: excessive sumoylation is a marker of defective spermatozoa. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
14 15456902 Distinct in vivo dynamics of vertebrate SUMO paralogues. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
15 21843595 Profiles of SUMO and ubiquitin conjugation in an Alzheimer's disease model. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
16 23078246 Small ubiquitin-like modifier 1-3 conjugation [corrected] is activated in human astrocytic brain tumors and is required for glioblastoma cell survival. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
17 17164289 Sumoylation dynamics during keratinocyte differentiation. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
18 26060329 SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
19 20385780 SUMO proteins are involved in the stress response during spermatogenesis and are localized to DNA double-strand breaks in germ cells. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
20 24690371 Neuron-specific Sumo1-3 knockdown in mice impairs episodic and fear memories. Pubmed 1.077E-12 7.152E-11 5.556E-10 1.430E-9 3 3
21 15487983 Mapping residues of SUMO precursors essential in differential maturation by SUMO-specific protease, SENP1. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
22 9891849 Characterization of mouse ubiquitin-like SMT3A and SMT3B cDNAs and gene/pseudogenes. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
23 28851805 C-terminal motifs in promyelocytic leukemia protein isoforms critically regulate PML nuclear body formation. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
24 16626738 Crystal structure of SUMO-3-modified thymine-DNA glycosylase. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
25 26675234 Identification of RNF168 as a PML nuclear body regulator. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
26 20181954 SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
27 15296745 A basis for SUMO protease specificity provided by analysis of human Senp2 and a Senp2-SUMO complex. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
28 19029252 The CTCF insulator protein is posttranslationally modified by SUMO. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
29 17428805 Noncovalent binding of small ubiquitin-related modifier (SUMO) protease to SUMO is necessary for enzymatic activities and cell growth. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
30 26867680 The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
31 23604351 Analysis of SUMOylated proteins using SUMO-traps. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
32 12810706 Modification of CCAAT/enhancer-binding protein-beta by the small ubiquitin-like modifier (SUMO) family members, SUMO-2 and SUMO-3. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
33 27343429 The SUMO2/3 specific E3 ligase ZNF451-1 regulates PML stability. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
34 18644859 Dual modification of BMAL1 by SUMO2/3 and ubiquitin promotes circadian activation of the CLOCK/BMAL1 complex. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
35 29269218 Temporal and SUMO-specific SUMOylation contribute to the dynamics of Polo-like kinase 1 (PLK1) and spindle integrity during mouse oocyte meiosis. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
36 28553222 Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
37 19919826 The p150 subunit of CAF-1 causes association of SUMO2/3 with the DNA replication foci. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
38 11889051 Modification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnover. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
39 24706897 Sumoylation differentially regulates Sp1 to control cell differentiation. Pubmed 4.308E-12 1.467E-10 1.140E-9 5.721E-9 3 4
40 23990779 Kaposi's sarcoma-associated herpesvirus K-Rta exhibits SUMO-targeting ubiquitin ligase (STUbL) like activity and is essential for viral reactivation. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
41 17099700 Structural basis for SENP2 protease interactions with SUMO precursors and conjugated substrates. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
42 21454548 Impairment of human immunodeficiency virus type-1 integrase SUMOylation correlates with an early replication defect. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
43 15923632 Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
44 18408734 RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
45 16428449 Inhibition of DNA binding by differential sumoylation of heat shock factors. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
46 16494873 Sumoylation of the SOX10 transcription factor regulates its transcriptional activity. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
47 21878624 Swapping small ubiquitin-like modifier (SUMO) isoform specificity of SUMO proteases SENP6 and SENP7. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
48 16553580 The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
49 25133527 Characterization of the SUMO-binding activity of the myeloproliferative and mental retardation (MYM)-type zinc fingers in ZNF261 and ZNF198. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
50 21949651 A viral ubiquitin ligase has substrate preferential SUMO targeted ubiquitin ligase activity that counteracts intrinsic antiviral defence. Pubmed 1.077E-11 2.860E-10 2.222E-9 1.430E-8 3 5
Show 45 more annotations

9: Interaction [Display Chart] 5 input genes in category / 538 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:SENP2 SENP2 interactions 1.366E-10 6.384E-8 4.384E-7 7.347E-8 4 42
2 int:TDG TDG interactions 2.373E-10 6.384E-8 4.384E-7 1.277E-7 4 48
3 int:SENP1 SENP1 interactions 4.159E-10 6.957E-8 4.777E-7 2.237E-7 4 55
4 int:SP100 SP100 interactions 5.173E-10 6.957E-8 4.777E-7 2.783E-7 4 58
5 int:RNF111 RNF111 interactions 1.117E-9 1.202E-7 8.254E-7 6.011E-7 4 70
6 int:HIPK2 HIPK2 interactions 1.481E-9 1.328E-7 9.116E-7 7.966E-7 4 75
7 int:PIAS2 PIAS2 interactions 3.254E-9 2.501E-7 1.717E-6 1.750E-6 4 91
8 int:SENP6 SENP6 interactions 7.346E-9 4.742E-7 3.256E-6 3.952E-6 3 17
9 int:ARC ARC interactions 8.815E-9 4.742E-7 3.256E-6 4.742E-6 3 18
10 int:SOX6 SOX6 interactions 8.815E-9 4.742E-7 3.256E-6 4.742E-6 3 18
11 int:CASP8AP2 CASP8AP2 interactions 2.483E-8 1.162E-6 7.975E-6 1.336E-5 3 25
12 int:PIAS1 PIAS1 interactions 2.595E-8 1.162E-6 7.975E-6 1.396E-5 4 152
13 int:USPL1 USPL1 interactions 2.807E-8 1.162E-6 7.975E-6 1.510E-5 3 26
14 int:DAXX DAXX interactions 4.171E-8 1.603E-6 1.101E-5 2.244E-5 4 171
15 int:FOS FOS interactions 4.685E-8 1.680E-6 1.154E-5 2.520E-5 4 176
16 int:ZNF451 ZNF451 interactions 5.352E-8 1.800E-6 1.236E-5 2.879E-5 3 32
17 int:SOX10 SOX10 interactions 6.456E-8 2.043E-6 1.403E-5 3.473E-5 3 34
18 int:TDP2 TDP2 interactions 1.636E-7 4.632E-6 3.181E-5 8.801E-5 3 46
19 int:SLX4 SLX4 interactions 1.636E-7 4.632E-6 3.181E-5 8.801E-5 3 46
20 int:USP25 USP25 interactions 2.381E-7 6.122E-6 4.203E-5 1.281E-4 3 52
21 int:PML PML interactions 2.389E-7 6.122E-6 4.203E-5 1.286E-4 4 264
22 int:WRN WRN interactions 2.825E-7 6.909E-6 4.744E-5 1.520E-4 3 55
23 int:JUN JUN interactions 3.780E-7 8.842E-6 6.071E-5 2.034E-4 4 296
24 int:SAE1 SAE1 interactions 4.070E-7 9.124E-6 6.265E-5 2.190E-4 3 62
25 int:MYB MYB interactions 4.274E-7 9.197E-6 6.314E-5 2.299E-4 3 63
26 int:PIAS3 PIAS3 interactions 4.700E-7 9.725E-6 6.677E-5 2.529E-4 3 65
27 int:TOPORS TOPORS interactions 5.391E-7 1.074E-5 7.375E-5 2.900E-4 3 68
28 int:RNF168 RNF168 interactions 6.147E-7 1.181E-5 8.109E-5 3.307E-4 3 71
29 int:ZMYM2 ZMYM2 interactions 7.557E-7 1.402E-5 9.626E-5 4.066E-4 3 76
30 int:TOP2B TOP2B interactions 9.168E-7 1.644E-5 1.129E-4 4.932E-4 3 81
31 int:PIAS4 PIAS4 interactions 2.069E-6 3.590E-5 2.465E-4 1.113E-3 3 106
32 int:UBE2I UBE2I interactions 2.526E-6 4.248E-5 2.916E-4 1.359E-3 4 476
33 int:BLM BLM interactions 4.785E-6 7.642E-5 5.247E-4 2.574E-3 3 140
34 int:RANGAP1 RANGAP1 interactions 4.889E-6 7.642E-5 5.247E-4 2.630E-3 3 141
35 int:ZCCHC12 ZCCHC12 interactions 4.972E-6 7.642E-5 5.247E-4 2.675E-3 2 13
36 int:PLAGL1 PLAGL1 interactions 5.800E-6 8.667E-5 5.951E-4 3.120E-3 2 14
37 int:RANBP2 RANBP2 interactions 6.008E-6 8.736E-5 5.998E-4 3.232E-3 3 151
38 int:ZMYM5 ZMYM5 interactions 6.691E-6 9.474E-5 6.505E-4 3.600E-3 2 15
39 int:TRIML2 TRIML2 interactions 8.665E-6 1.174E-4 8.063E-4 4.662E-3 2 17
40 int:UBA2 UBA2 interactions 8.731E-6 1.174E-4 8.063E-4 4.697E-3 3 171
41 int:SENP5 SENP5 interactions 9.747E-6 1.249E-4 8.572E-4 5.244E-3 2 18
42 int:CCNE2 CCNE2 interactions 9.747E-6 1.249E-4 8.572E-4 5.244E-3 2 18
43 int:SIMC1 SIMC1 interactions 1.089E-5 1.363E-4 9.357E-4 5.860E-3 2 19
44 int:CHAF1A CHAF1A interactions 1.759E-5 2.151E-4 1.477E-3 9.466E-3 3 216
45 int:RAD54L2 RAD54L2 interactions 2.069E-5 2.473E-4 1.698E-3 1.113E-2 2 26
46 int:ZCCHC7 ZCCHC7 interactions 2.405E-5 2.813E-4 1.932E-3 1.294E-2 2 28
47 int:EME1 EME1 interactions 2.583E-5 2.957E-4 2.030E-3 1.390E-2 2 29
48 int:MSX1 MSX1 interactions 2.958E-5 3.315E-4 2.276E-3 1.591E-2 2 31
49 int:C18orf25 C18orf25 interactions 5.736E-5 6.298E-4 4.324E-3 3.086E-2 2 43
50 int:HSF2 HSF2 interactions 6.864E-5 7.386E-4 5.071E-3 3.693E-2 2 47
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 12q13.11-q13.3 12q13.11-q13.3 1.443E-4 7.213E-4 1.647E-3 7.213E-4 1 1
2 2q33 2q33 4.177E-3 6.961E-3 1.589E-2 2.088E-2 1 29
3 15q22 15q22 4.177E-3 6.961E-3 1.589E-2 2.088E-2 1 29
4 17q25.1 17q25.1 1.192E-2 1.490E-2 3.401E-2
5.958E-2
 1 83
5 21q22.3 21q22.3 1.961E-2 1.961E-2 4.477E-2
9.804E-2
 1 137

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 52 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 2 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1024 DNA glycosylases genenames.org 1.209E-3 3.627E-3 6.649E-3 3.627E-3 1 11
2 59 Ring finger proteins|Tripartite motif containing genenames.org 1.053E-2 1.579E-2 2.894E-2 3.158E-2 1 96
3 58 Ring finger proteins|Tripartite motif containing genenames.org 3.000E-2 3.000E-2
5.500E-2
9.001E-2
 1 275

13: Coexpression [Display Chart] 5 input genes in category / 524 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M12016 Genes up-regulated in epithelial ovarian cancer (EOC) biopsies: invasive (TOV) vs low malignant potential (LMP) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.510E-4 3.191E-2
2.183E-1
1.315E-1
 2 117
2 15940270-Figure1D Human Ovarian Ouellet05 137genes GeneSigDB 3.098E-4 3.191E-2
2.183E-1
1.624E-1
 2 130
3 M6825 Genes up-regulated in monocytes: untreated versus anti- FcgRIIB. MSigDB C7: Immunologic Signatures (v6.0) 5.045E-4 3.191E-2
2.183E-1
2.643E-1
 2 166
4 M8242 Genes down-regulated in polarizing CD4 [GeneID=920] Th17 cells: wildtype versus RORC [GeneID=6097] knockout. MSigDB C7: Immunologic Signatures (v6.0) 5.105E-4 3.191E-2
2.183E-1
2.675E-1
 2 167
5 18691415-Table5e Human Colon Solmi08 204genes GeneSigDB 6.059E-4 3.191E-2
2.183E-1
3.175E-1
 2 182
6 M4916 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from LAIV influenza vaccinee pre-vaccination versus those at day 3 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 7.092E-4 3.191E-2
2.183E-1
3.716E-1
 2 197
7 M7372 Genes down-regulated in the activated CD4 [GeneID=920] T cells (48h): IL-12 versus IL-12 and IL18 [GeneID=3606]. MSigDB C7: Immunologic Signatures (v6.0) 7.164E-4 3.191E-2
2.183E-1
3.754E-1
 2 198
8 M3136 Genes up-regulated in comparison of macrophages cultured with M-CSF [GeneID=1435] versus macrophages cultured with M-CSF [GeneID=1435] and Pam3Cyc. MSigDB C7: Immunologic Signatures (v6.0) 7.236E-4 3.191E-2
2.183E-1
3.792E-1
 2 199
9 M9493 Genes up-regulated in CD8 T effector cells at day 6 of chronic infection: LCMV-Armstrong versus LCMV-Clone 13. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.191E-2
2.183E-1
3.830E-1
 2 200
10 M8867 Genes down-regulated in common lymphoid progenitor versus pro-B cells. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.191E-2
2.183E-1
3.830E-1
 2 200
11 M9455 Genes up-regulated in CD8 T cells: naïve versus effectors at day 6. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.191E-2
2.183E-1
3.830E-1
 2 200
12 M5239 Genes up-regulated in comparison of macrophages exposed to L. donovani versus macrophages exposed to 5 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 7.309E-4 3.191E-2
2.183E-1
3.830E-1
 2 200
13 M11563 Genes involved in DNA repair, compiled manually by the authors. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.647E-4 3.773E-2
2.581E-1
5.055E-1
 2 230
14 M8897 Down-regulated genes whose expression correlates with copy number losses in pancreatic adenocarcinoma cell lines and primary tumor specimens. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.024E-3 3.773E-2
2.581E-1
5.365E-1
 2 237
15 M15409 Amplification hot spot 3: colocolized fragile sites and cancer genes in the 15q21-q26 region. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.080E-3 3.773E-2
2.581E-1
5.660E-1
 1 5
16 15517866-Table6 Human Mouth Ruutu04 7genes GeneSigDB 1.512E-3 4.767E-2
3.260E-1
7.923E-1
 1 7
17 M19745 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.720E-3 4.767E-2
3.260E-1
9.014E-1
 2 308
18 M1228 Genes down-regulated in the UMUC-3 cells (bladder cancer) after knockdown of RALB [GeneID=5899] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.944E-3 4.767E-2
3.260E-1
1.000E0
 1 9
19 M2023 Genes in cluster 5: slowly down-regulated in HFW cells (fibroblast) by sodium arsenite [PubChem=26435]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.159E-3 4.767E-2
3.260E-1
1.000E0
 1 10
20 16288054-Table2b Human Ovarian Bonome05 13genes GeneSigDB 2.591E-3 4.767E-2
3.260E-1
1.000E0
 1 12
21 15387888-Table1c Human Breast Gwinn04 16genes GeneSigDB 3.238E-3 4.767E-2
3.260E-1
1.000E0
 1 15
22 18722011-SuppTable2m Human Leukemia Sanchez-Guijo08 15genes GeneSigDB 3.238E-3 4.767E-2
3.260E-1
1.000E0
 1 15
23 16152586-Table1 Human Breast Chinnaiyan06 71genes saha GeneSigDB 3.238E-3 4.767E-2
3.260E-1
1.000E0
 1 15
24 M14495 Genes up-regulated in MDA-MB-231 cells (breast cancer) after knockdown of PRKCA and ETS1 [GeneID=5578;2113] by RNAi. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.453E-3 4.767E-2
3.260E-1
1.000E0
 1 16
25 M2013 Genes with intermediate-CpG-density promoters (ICP) bearing histone H3 trimethylation mark at K4 (H3K4me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.552E-3 4.767E-2
3.260E-1
1.000E0
 2 445
26 M609 Genes down-regulated in adult T-cell leukemia (ATL), chronic vs acute clinical condition. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.884E-3 4.767E-2
3.260E-1
1.000E0
 1 18
27 18794103-Table3 Human Skin Zimmerer08 23genes InVitrovsInVivo GeneSigDB 4.100E-3 4.767E-2
3.260E-1
1.000E0
 1 19
28 M2558 Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive ALL (B- and T-lineage ALL); here - genes up-regulated in the drug resistant samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.100E-3 4.767E-2
3.260E-1
1.000E0
 1 19
29 16909099-SuppTable2 Human Leukemia Choi07 21genes GeneSigDB 4.315E-3 4.767E-2
3.260E-1
1.000E0
 1 20
30 M2547 Genes distinguishing prednisolone [PubChem=5755] resistant and sensitive B-lineage ALL; here - genes up-regulated in the drug resistant samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.746E-3 4.767E-2
3.260E-1
1.000E0
 1 22
31 M10172 Genes from the yellow module which are down-regulated in HAEC cells (primary aortic endothelium) after exposure to the oxidized 1-palmitoyl-2-arachidonyl-sn-3-glycerophosphorylcholine (oxPAPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.961E-3 4.767E-2
3.260E-1
1.000E0
 1 23
32 M2566 Genes distinguishing asparaginase resistant and sensitive ALL (B- and T-lineage ALL); here - genes down-regulated in the drug resistant samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.391E-3 4.767E-2
3.260E-1
1.000E0
 1 25
33 11906190-Table1b-1 Human Colon Iizaka02 31genes GeneSigDB 5.822E-3 4.767E-2
3.260E-1
1.000E0
 1 27
34 M1391 Cluster 7 of genes distinguishing among different B lymphocyte neoplasms. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.822E-3 4.767E-2
3.260E-1
1.000E0
 1 27
35 20145155-Table1 Human StemCell Lottaz10 30genes GeneSigDB 6.037E-3 4.767E-2
3.260E-1
1.000E0
 1 28
36 20166207-Table7 Human Leukemia Rigolin10 35genes GeneSigDB 6.252E-3 4.767E-2
3.260E-1
1.000E0
 1 29
37 11861292-Table2 Human BoneMarrow Zhan02 30genes GeneSigDB 6.252E-3 4.767E-2
3.260E-1
1.000E0
 1 29
38 M17405 Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.467E-3 4.767E-2
3.260E-1
1.000E0
 1 30
39 20145155-Table3 Human StemCell Lottaz10 31genes GeneSigDB 6.682E-3 4.767E-2
3.260E-1
1.000E0
 1 31
40 M1902 Genes up-regulated in fibroblasts from MLL [GeneID=4297] knockout mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.541E-3 4.767E-2
3.260E-1
1.000E0
 1 35
41 M5919 Genes up-regulated by activation of hedgehog signaling. MSigDB H: Hallmark Gene Sets (v6.0) 7.756E-3 4.767E-2
3.260E-1
1.000E0
 1 36
42 19749798-TableS3 Human Lung Olaussen09 58genes GeneSigDB 8.186E-3 4.767E-2
3.260E-1
1.000E0
 1 38
43 18722011-SuppTable2i Human Leukemia Sanchez-Guijo08 41genes GeneSigDB 8.400E-3 4.767E-2
3.260E-1
1.000E0
 1 39
44 11906190-Table1b-2 Human Colon Iizaka02 47genes GeneSigDB 8.615E-3 4.767E-2
3.260E-1
1.000E0
 1 40
45 18400362-Figure1a Human Lymphoma Staege08 50genes UpRegulated HodgkinlymphvNorm GeneSigDB 9.259E-3 4.767E-2
3.260E-1
1.000E0
 1 43
46 19525979-SuppTable2 Human Lung Baras09 50genes SCCvsBSM GeneSigDB 9.259E-3 4.767E-2
3.260E-1
1.000E0
 1 43
47 M2569 Genes changed in pre-B lymphoblastic leukemia cells with BCR-ABL1 fusion [GeneID=613, 25] vs normal pre-B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.688E-3 4.767E-2
3.260E-1
1.000E0
 1 45
48 M4710 Up-regulated at 8 h following infection of primary human foreskin fibroblasts with CMV MSigDB C2: CGP Curated Gene Sets (v6.0) 1.012E-2 4.767E-2
3.260E-1
1.000E0
 1 47
49 18691624-Table1 Human Viral Harenberg08 60genes GeneSigDB 1.055E-2 4.767E-2
3.260E-1
1.000E0
 1 49
50 11906190-Table2b-2 Human Colon Iizaka02 72genes GeneSigDB 1.076E-2 4.767E-2
3.260E-1
1.000E0
 1 50
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 5 input genes in category / 357 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal-Cortex post-natal kidney Renal cell carcinoma/Kidney Normal-Cortex post-natal kidney T17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal-Cortex post-natal kidney Renal cell carcinoma/Kidney Normal-Cortex post-natal kidney T17 Adult, Development, and Cancer types 2.210E-5 7.890E-3
5.094E-2
 7.890E-3 2 33
2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal RCC R U/Kidney Normal RCC R14 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal RCC R U/Kidney Normal RCC R14 Adult, Development, and Cancer types 2.142E-4 2.557E-2
1.651E-1
7.648E-2
 2 102
3 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour Wilms U U/Kidney Tumour Wilms U26 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour Wilms U U/Kidney Tumour Wilms U26 Adult, Development, and Cancer types 6.362E-4 2.557E-2
1.651E-1
2.271E-1
 2 176
4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal Wilms Fetus other/Kidney Normal Wilms F13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Fetus other/Kidney Normal Wilms Fetus other/Kidney Normal Wilms F13 Adult, Development, and Cancer types 6.800E-4 2.557E-2
1.651E-1
2.428E-1
 2 182
5 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal-Cortex post-natal kidney EN-B/Kidney Normal-Cortex post-natal kidney EN16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney EN-B/Kidney Normal-Cortex post-natal kidney EN-B/Kidney Normal-Cortex post-natal kidney EN16 Adult, Development, and Cancer types 6.950E-4 2.557E-2
1.651E-1
2.481E-1
 2 184
6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal PapRCC Endothelium/Kidney Normal PapRCC T2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal PapRCC Endothelium/Kidney Normal PapRCC T2 Adult, Development, and Cancer types 7.177E-4 2.557E-2
1.651E-1
2.562E-1
 2 187
7 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Tumour VHL RCC IF-U/Kidney Tumour VHL RCC IF17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney IF-U/Kidney Tumour VHL RCC IF-U/Kidney Tumour VHL RCC IF17 Adult, Development, and Cancer types 7.330E-4 2.557E-2
1.651E-1
2.617E-1
 2 189
8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney NephrogenicRest Wilms Nephrogenesis/Kidney NephrogenicRest Wilms F10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Nephrogenesis/Kidney NephrogenicRest Wilms Nephrogenesis/Kidney NephrogenicRest Wilms F10 Adult, Development, and Cancer types 7.485E-4 2.557E-2
1.651E-1
2.672E-1
 2 191
9 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2/Kidney Normal fetal kidney MNP2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP2/Kidney Normal fetal kidney MNP2 Adult, Development, and Cancer types 7.642E-4 2.557E-2
1.651E-1
2.728E-1
 2 193
10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal RCC NK cell/Kidney Normal RCC NK17 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal RCC NK cell/Kidney Normal RCC NK17 Adult, Development, and Cancer types 7.721E-4 2.557E-2
1.651E-1
2.756E-1
 2 194
11 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour Wilms PT-U/Kidney Tumour Wilms PT26 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney PT-U/Kidney Tumour Wilms PT-U/Kidney Tumour Wilms PT26 Adult, Development, and Cancer types 7.880E-4 2.557E-2
1.651E-1
2.813E-1
 2 196
12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK10 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK10 Adult, Development, and Cancer types 9.160E-4 2.725E-2
1.759E-1
3.270E-1
 1 4
13 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Normal cell/Kidney Tumour Wilms Normal cell/Kidney Tumour Wilms T14 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Normal cell/Kidney Tumour Wilms Normal cell/Kidney Tumour Wilms T14 Adult, Development, and Cancer types 1.374E-3 3.645E-2
2.354E-1
4.904E-1
 1 6
14 Kidney10XCellRanger Six2TGC TSC1 E14 Stroma Stroma Subtype E14-Six2TGC Tsc1-Stroma1-C2-KC2 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Stroma Stroma Subtype E14-Six2TGC Tsc1-Stroma1-C2-KC2 Top 200 Genes 1.444E-3 3.645E-2
2.354E-1
5.155E-1
 2 266
15 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC-cycle Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC-cycle Top 200 Genes 1.796E-3 3.645E-2
2.354E-1
6.410E-1
 2 297
16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Medulla Wilms NK cell/Kidney Normal-Medulla Wilms NK8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Normal-Medulla Wilms NK cell/Kidney Normal-Medulla Wilms NK8 Adult, Development, and Cancer types 1.831E-3 3.645E-2
2.354E-1
6.538E-1
 1 8
17 Kidney10XCellRanger Six2KI E14 NPC NPC Subtype E14-Six2KI-NPCU-C6-KC2 Top 200 Genes Kidney10XCellRanger Six2KI E14 NPC NPC Subtype E14-Six2KI-NPCU-C6-KC2 Top 200 Genes 1.844E-3 3.645E-2
2.354E-1
6.582E-1
 2 301
18 Human Cell Atlas Human Cell Atlas Immune Immune Subtype CD34+ pre-T Top 200 Genes Human Cell Atlas Human Cell Atlas Immune Immune Subtype CD34+ pre-T Top 200 Genes 1.954E-3 3.645E-2
2.354E-1
6.977E-1
 2 310
19 Kidney10XCellRanger Six2KI E14 NPC NPC Subtype E14-Six2KI-NPCU-C1-KC3 Top 200 Genes Kidney10XCellRanger Six2KI E14 NPC NPC Subtype E14-Six2KI-NPCU-C1-KC3 Top 200 Genes 2.004E-3 3.645E-2
2.354E-1
7.155E-1
 2 314
20 JC iEC 2500 K2 JC iEC top-relative-expression-ranked 2500 k-means-cluster#2 PCBC 2.042E-3 3.645E-2
2.354E-1
7.291E-1
 2 317
21 Kidney10XCellRanger Six2KI E14 NPC NPC Subtype E14-Six2KI-NPCC-C3-KC6 Top 200 Genes Kidney10XCellRanger Six2KI E14 NPC NPC Subtype E14-Six2KI-NPCC-C3-KC6 Top 200 Genes 2.251E-3 3.826E-2
2.470E-1
8.035E-1
 2 333
22 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Wilms tumour and fibroblast/Kidney Normal fetal kidney Wilms tumour and fibroblast Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Wilms tumour and fibroblast/Kidney Normal fetal kidney Wilms tumour and fibroblast Adult, Development, and Cancer types 2.517E-3 4.085E-2
2.637E-1
8.987E-1
 1 11
23 10X Human 68K PBMC CD19+ B Subtype CD19+ B-CD19+ B c4 Top 200 Genes 10X Human 68K PBMC CD19+ B Subtype CD19+ B-CD19+ B c4 Top 200 Genes 2.800E-3 4.325E-2
2.793E-1
9.994E-1
 2 372
24 10X Human 68K PBMC CD34+ Subtype CD34+-CD34+ c6 Top 200 Genes 10X Human 68K PBMC CD34+ Subtype CD34+-CD34+ c6 Top 200 Genes 3.011E-3 4.325E-2
2.793E-1
1.000E0
 2 386
25 10X Human 68K PBMC CD8+ Cytotoxic T Subtype CD8+ Cytotoxic T-CD8+ Cytotoxic T c6 Top 200 Genes 10X Human 68K PBMC CD8+ Cytotoxic T Subtype CD8+ Cytotoxic T-CD8+ Cytotoxic T c6 Top 200 Genes 3.103E-3 4.325E-2
2.793E-1
1.000E0
 2 392
26 10X Human 68K PBMC CD8+ Cytotoxic T Subtype CD8+ Cytotoxic T-CD8+ Cytotoxic T c1 Top 200 Genes 10X Human 68K PBMC CD8+ Cytotoxic T Subtype CD8+ Cytotoxic T-CD8+ Cytotoxic T c1 Top 200 Genes 3.150E-3 4.325E-2
2.793E-1
1.000E0
 2 395
Show 21 more annotations

15: Computational [Display Chart] 4 input genes in category / 110 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M12947 MORF CTBP1 Neighborhood of CTBP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.820E-5 5.803E-4 3.066E-3 2.002E-3 3 168
2 M7181 MORF PPP1CA Neighborhood of PPP1CA MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.853E-5 5.803E-4 3.066E-3 2.038E-3 3 169
3 M11132 MORF RAD21 Neighborhood of RAD21 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.315E-5 5.803E-4 3.066E-3 2.546E-3 3 182
4 M9350 MORF RAB1A Neighborhood of RAB1A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.804E-5 5.803E-4 3.066E-3 3.085E-3 3 194
5 M19884 MORF ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.936E-5 5.803E-4 3.066E-3 3.230E-3 3 197
6 M12287 MORF SKP1A Neighborhood of SKP1A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.166E-5 5.803E-4 3.066E-3 3.482E-3 3 202
7 M2967 MORF AP2M1 Neighborhood of AP2M1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.924E-5 6.166E-4 3.257E-3 4.316E-3 3 217
8 M11080 MORF HDAC1 Neighborhood of HDAC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.288E-5 7.897E-4 4.171E-3 6.917E-3 3 254
9 M7191 MORF DEK Neighborhood of DEK MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.899E-5 7.897E-4 4.171E-3 7.589E-3 3 262
10 M17615 MORF RAN Neighborhood of RAN MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.383E-5 7.897E-4 4.171E-3 8.121E-3 3 268
11 M6582 GCM RAD21 Neighborhood of RAD21 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.897E-5 7.897E-4 4.171E-3 8.687E-3 2 37
12 M15851 MORF SART1 Neighborhood of SART1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.308E-4 2.115E-3 1.117E-2 2.539E-2 2 63
13 M14834 MORF SP3 Neighborhood of SP3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.726E-4 3.152E-3 1.665E-2 4.098E-2 2 80
14 M1232 MORF RAF1 Neighborhood of RAF1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.040E-4 5.531E-3 2.922E-2
7.744E-2
 2 110
15 M16184 MORF ERH Neighborhood of ERH MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.559E-4 5.544E-3 2.928E-2
8.315E-2
 2 114
16 M1958 MORF ACTG1 Neighborhood of ACTG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.106E-3 7.153E-3 3.779E-2
1.216E-1
 2 138
17 M6545 MORF FBL Neighborhood of FBL MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.122E-3 7.153E-3 3.779E-2
1.234E-1
 2 139
18 M18071 MORF PRKAR1A Neighborhood of PRKAR1A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.171E-3 7.153E-3 3.779E-2
1.288E-1
 2 142
19 M19908 MORF NME2 Neighborhood of NME2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.375E-3 7.962E-3 4.206E-2
1.513E-1
 2 154
20 M9993 MORF NPM1 Neighborhood of NPM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.521E-3 8.364E-3 4.418E-2
1.673E-1
 2 162
21 M19767 MORF G22P1 Neighborhood of G22P1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.693E-3 8.868E-3 4.684E-2
1.862E-1
 2 171
22 M19325 MORF PSMC1 Neighborhood of PSMC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.086E-3 1.029E-2
5.436E-2
2.294E-1
 2 190
23 M6058 MORF DAP3 Neighborhood of DAP3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.152E-3 1.029E-2
5.436E-2
2.367E-1
 2 193
24 M2705 MORF ACP1 Neighborhood of ACP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.543E-3 1.129E-2
5.965E-2
2.797E-1
 2 210
25 M5796 MORF RAC1 Neighborhood of RAC1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.567E-3 1.129E-2
5.965E-2
2.823E-1
 2 211
26 M10939 MORF UBE2I Neighborhood of UBE2I MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.255E-3 1.377E-2
7.275E-2
3.581E-1
 2 238
27 M18002 MORF CSNK2B Neighborhood of CSNK2B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.706E-3 1.917E-2
1.013E-1
5.177E-1
 2 287
28 M7309 MORF RAD23A Neighborhood of RAD23A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.751E-3 2.564E-2
1.354E-1
7.426E-1
 2 345
29 M11473 MODULE 352 Nuclear pore complex. MSigDb: C4 - CM: Cancer Modules (v6.0) 6.759E-3 2.564E-2
1.354E-1
7.435E-1
 1 17
30 M19318 MODULE 4 Genes in the cancer module 4. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.344E-3 3.059E-2
1.616E-1
9.178E-1
 1 21
31 M16146 MODULE 82 Genes in the cancer module 82. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.532E-3 3.382E-2
1.787E-1
1.000E0
 1 24
32 M14651 GNF2 TDG Neighborhood of TDG MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.388E-2 4.745E-2
2.506E-1
1.000E0
 1 35
33 M4536 GNF2 G22P1 Neighborhood of G22P1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.427E-2 4.745E-2
2.506E-1
1.000E0
 1 36
34 M12593 GNF2 ANP32B Neighborhood of ANP32B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.467E-2 4.745E-2
2.506E-1
1.000E0
 1 37
35 M5537 GNF2 PPP6C Neighborhood of PPP6C MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.545E-2 4.857E-2
2.566E-1
1.000E0
 1 39
Show 30 more annotations

16: MicroRNA [Display Chart] 5 input genes in category / 263 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-638:mirSVR lowEffct hsa-miR-638:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 2.995E-4 2.536E-2
1.560E-1
7.876E-2
 2 398
2 hsa-miR-720:mirSVR lowEffct hsa-miR-720:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.064E-4 2.536E-2
1.560E-1
1.069E-1
 2 464
3 hsa-miR-139-3p:mirSVR lowEffct hsa-miR-139-3p:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.205E-4 2.536E-2
1.560E-1
1.106E-1
 2 472
4 hsa-miR-4664-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.536E-4 2.536E-2
1.560E-1
1.456E-1
 1 8
5 hsa-miR-431-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.920E-4 2.536E-2
1.560E-1
1.820E-1
 1 10
6 hsa-let-7e-3p:Functional MTI Functional MTI miRTarbase 7.611E-4 2.536E-2
1.560E-1
2.002E-1
 1 11
7 hsa-miR-8078:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.245E-3 2.536E-2
1.560E-1
3.275E-1
 1 18
8 hsa-miR-624-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.627E-3 2.536E-2
1.560E-1
6.910E-1
 1 38
9 hsa-miR-1203:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.766E-3 2.536E-2
1.560E-1
7.273E-1
 1 40
10 hsa-miR-4761-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.042E-3 2.536E-2
1.560E-1
8.000E-1
 1 44
11 hsa-miR-4474-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.180E-3 2.536E-2
1.560E-1
8.363E-1
 1 46
12 hsa-miR-3162-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.249E-3 2.536E-2
1.560E-1
8.545E-1
 1 47
13 hsa-miR-4320:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 2.536E-2
1.560E-1
8.908E-1
 1 49
14 hsa-miR-3661:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 2.536E-2
1.560E-1
8.908E-1
 1 49
15 hsa-miR-631:Functional MTI Functional MTI miRTarbase 3.525E-3 2.536E-2
1.560E-1
9.271E-1
 1 51
16 hsa-miR-4427:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.663E-3 2.536E-2
1.560E-1
9.634E-1
 1 53
17 hsa-miR-6797-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.008E-3 2.536E-2
1.560E-1
1.000E0
 1 58
18 hsa-miR-3074-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 2.536E-2
1.560E-1
1.000E0
 1 59
19 hsa-miR-6076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 2.536E-2
1.560E-1
1.000E0
 1 59
20 hsa-miR-1244:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.077E-3 2.536E-2
1.560E-1
1.000E0
 1 59
21 hsa-miR-4450:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.491E-3 2.536E-2
1.560E-1
1.000E0
 1 65
22 hsa-miR-619-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.629E-3 2.536E-2
1.560E-1
1.000E0
 1 67
23 hsa-miR-3184-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.629E-3 2.536E-2
1.560E-1
1.000E0
 1 67
24 hsa-miR-1180-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.629E-3 2.536E-2
1.560E-1
1.000E0
 1 67
25 hsa-miR-6868-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.698E-3 2.536E-2
1.560E-1
1.000E0
 1 68
26 hsa-miR-4679:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.767E-3 2.536E-2
1.560E-1
1.000E0
 1 69
27 hsa-miR-4764-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.767E-3 2.536E-2
1.560E-1
1.000E0
 1 69
28 hsa-miR-654-3p:Functional MTI Functional MTI miRTarbase 4.836E-3 2.536E-2
1.560E-1
1.000E0
 1 70
29 hsa-miR-1265:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.974E-3 2.536E-2
1.560E-1
1.000E0
 1 72
30 CTCAAGA,MIR-526B:MSigDB CTCAAGA,MIR-526B:MSigDB MSigDB 4.974E-3 2.536E-2
1.560E-1
1.000E0
 1 72
31 hsa-miR-4677-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 2.536E-2
1.560E-1
1.000E0
 1 74
32 hsa-miR-4461:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.111E-3 2.536E-2
1.560E-1
1.000E0
 1 74
33 hsa-miR-2054:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 2.536E-2
1.560E-1
1.000E0
 1 75
34 hsa-miR-4424:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.180E-3 2.536E-2
1.560E-1
1.000E0
 1 75
35 hsa-miR-4254:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.249E-3 2.536E-2
1.560E-1
1.000E0
 1 76
36 hsa-miR-380-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.318E-3 2.536E-2
1.560E-1
1.000E0
 1 77
37 hsa-miR-6757-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.525E-3 2.536E-2
1.560E-1
1.000E0
 1 80
38 hsa-miR-8076:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.525E-3 2.536E-2
1.560E-1
1.000E0
 1 80
39 TCTGGAC,MIR-198:MSigDB TCTGGAC,MIR-198:MSigDB MSigDB 5.594E-3 2.536E-2
1.560E-1
1.000E0
 1 81
40 hsa-miR-1207-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.801E-3 2.536E-2
1.560E-1
1.000E0
 1 84
41 hsa-miR-450b-3p:PITA hsa-miR-450b-3p:PITA TOP PITA 5.869E-3 2.536E-2
1.560E-1
1.000E0
 1 85
42 hsa-miR-769-3p:PITA hsa-miR-769-3p:PITA TOP PITA 5.938E-3 2.536E-2
1.560E-1
1.000E0
 1 86
43 hsa-miR-8071:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.007E-3 2.536E-2
1.560E-1
1.000E0
 1 87
44 hsa-miR-5585-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.145E-3 2.536E-2
1.560E-1
1.000E0
 1 89
45 hsa-miR-5700:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.214E-3 2.536E-2
1.560E-1
1.000E0
 1 90
46 hsa-miR-4276:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.420E-3 2.536E-2
1.560E-1
1.000E0
 1 93
47 hsa-miR-4263:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.489E-3 2.536E-2
1.560E-1
1.000E0
 1 94
48 hsa-miR-6866-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.489E-3 2.536E-2
1.560E-1
1.000E0
 1 94
49 hsa-miR-6782-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.558E-3 2.536E-2
1.560E-1
1.000E0
 1 95
50 hsa-miR-7845-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.765E-3 2.536E-2
1.560E-1
1.000E0
 1 98
Show 45 more annotations

17: Drug [Display Chart] 5 input genes in category / 3302 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000193570 diazonaphthalene -- disulfonic acid Stitch 3.623E-11 1.196E-7 1.038E-6 1.196E-7 4 39
2 CID000502256 G-*-T Stitch 4.228E-10 6.981E-7 6.059E-6 1.396E-6 3 9
3 CID005327152 1 C2 Stitch 1.723E-9 1.897E-6 1.646E-5 5.691E-6 4 100
4 CID000065040 5-methylcytosine Stitch 5.235E-8 4.321E-5 3.751E-4 1.729E-4 4 233
5 CID000115150 ICRF-193 Stitch 1.245E-7 8.221E-5 7.136E-4 4.111E-4 3 54
6 CID000002538 NSC302991 Stitch 2.771E-7 1.525E-4 1.323E-3 9.149E-4 4 353
7 CID000027652 antimony(III) oxide Stitch 8.047E-7 3.796E-4 3.295E-3 2.657E-3 2 7
8 CID000007833 4-vinylcyclohexene diepoxide Stitch 9.377E-7 3.870E-4 3.359E-3 3.096E-3 3 105
9 CID000011163 glycylglycine Stitch 1.368E-6 4.554E-4 3.953E-3 4.518E-3 3 119
10 ctd:C037554 antimony trioxide CTD 1.379E-6 4.554E-4 3.953E-3 4.554E-3 2 9
11 CID000448615 AC1L9M5J Stitch 8.809E-6 2.644E-3 2.295E-2 2.909E-2 3 221
12 CID000151108 quebrachitol Stitch 1.553E-5 4.273E-3 3.709E-2
5.127E-2
 2 29
13 CID000002353 berberine Stitch 1.790E-5 4.546E-3 3.946E-2
5.910E-2
 3 280
14 ctd:D005033 Ethylmaleimide CTD 2.408E-5 5.603E-3 4.863E-2
7.951E-2
 2 36
15 CID000001135 thymine Stitch 2.545E-5 5.603E-3 4.863E-2
8.405E-2
 3 315
16 CID000006496 vinyl sulfone Stitch 5.061E-5 1.045E-2
9.066E-2
1.671E-1
 2 52
17 CID000447348 Pa-4 Stitch 5.876E-5 1.141E-2
9.906E-2
1.940E-1
 2 56
18 CID000014888 arsenic trioxide Stitch 8.289E-5 1.465E-2
1.271E-1
2.737E-1
 3 468
19 CID000007573 IPPD Stitch 8.428E-5 1.465E-2
1.271E-1
2.783E-1
 2 67
20 CID000007808 4-bromophenol Stitch 9.469E-5 1.563E-2
1.357E-1
3.127E-1
 2 71
21 CID000446591 AC1O6W2C Stitch 1.057E-4 1.662E-2
1.443E-1
3.490E-1
 2 75
22 CID000006956 phthalamide Stitch 1.234E-4 1.815E-2
1.575E-1
4.073E-1
 2 81
23 ctd:D000966 Antimony Potassium Tartrate CTD 1.264E-4 1.815E-2
1.575E-1
4.175E-1
 2 82
24 CID016043735 99mTc-DG Stitch 2.189E-4 2.098E-2
1.821E-1
7.228E-1
 1 1
25 CID000124584 16-iodo-3-methylhexadecanoic acid Stitch 2.189E-4 2.098E-2
1.821E-1
7.228E-1
 1 1
26 ctd:C454115 ReAsH-EDT2 compound CTD 2.189E-4 2.098E-2
1.821E-1
7.228E-1
 1 1
27 CID000314420 NSC-231870 Stitch 2.189E-4 2.098E-2
1.821E-1
7.228E-1
 1 1
28 CID000450601 AC1L9P1E Stitch 2.189E-4 2.098E-2
1.821E-1
7.228E-1
 1 1
29 CID000000849 pipecolic acid Stitch 2.402E-4 2.098E-2
1.821E-1
7.933E-1
 2 113
30 CID000656983 AC1LCVTP Stitch 2.620E-4 2.098E-2
1.821E-1
8.650E-1
 2 118
31 CID000000275 canavanin Stitch 2.800E-4 2.098E-2
1.821E-1
9.246E-1
 2 122
32 ctd:C010889 5-chlorouracil CTD 4.378E-4 2.098E-2
1.821E-1
1.000E0
 1 2
33 CID000128077 FMG Stitch 4.378E-4 2.098E-2
1.821E-1
1.000E0
 1 2
34 CID000142861 WF-3 Stitch 4.378E-4 2.098E-2
1.821E-1
1.000E0
 1 2
35 CID003081641 UDP-FDG Stitch 4.378E-4 2.098E-2
1.821E-1
1.000E0
 1 2
36 CID000132136 FTHA Stitch 4.378E-4 2.098E-2
1.821E-1
1.000E0
 1 2
37 CID000656410 [18f]fpt Stitch 4.378E-4 2.098E-2
1.821E-1
1.000E0
 1 2
38 CID000004865 C22H22O8 Stitch 5.052E-4 2.098E-2
1.821E-1
1.000E0
 2 164
39 ctd:C408982 CPG-oligonucleotide CTD 6.352E-4 2.098E-2
1.821E-1
1.000E0
 2 184
40 6243 UP Retinoic acid [302-79-4]; Up 200; 13.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.421E-4 2.098E-2
1.821E-1
1.000E0
 2 185
41 5930 UP pioglitazone HCl; Up 200; 10uM; PC3; HT HG-U133A Broad Institute CMAP Up 6.490E-4 2.098E-2
1.821E-1
1.000E0
 2 186
42 ctd:C572919 PP242 CTD 6.566E-4 2.098E-2
1.821E-1
1.000E0
 1 3
43 CID000034058 gallium citrate Stitch 6.566E-4 2.098E-2
1.821E-1
1.000E0
 1 3
44 CID000124162 beta-D-glucosyl-hydroxymethyluracil Stitch 6.566E-4 2.098E-2
1.821E-1
1.000E0
 1 3
45 CID003081493 FDG-6-P Stitch 6.566E-4 2.098E-2
1.821E-1
1.000E0
 1 3
46 CID005272744 SMFU Stitch 6.566E-4 2.098E-2
1.821E-1
1.000E0
 1 3
47 2053 DN Disulfiram [97-77-8]; Down 200; 13.4uM; PC3; HT HG-U133A Broad Institute CMAP Down 6.630E-4 2.098E-2
1.821E-1
1.000E0
 2 188
48 6253 UP Ellipticine [519-23-3]; Up 200; 16.2uM; MCF7; HT HG-U133A Broad Institute CMAP Up 6.771E-4 2.098E-2
1.821E-1
1.000E0
 2 190
49 4563 DN Thiostrepton [1393-48-2]; Down 200; 2.4uM; PC3; HT HG-U133A Broad Institute CMAP Down 6.842E-4 2.098E-2
1.821E-1
1.000E0
 2 191
50 2499 DN Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; HL60; HT HG-U133A Broad Institute CMAP Down 6.842E-4 2.098E-2
1.821E-1
1.000E0
 2 191
Show 45 more annotations

18: Disease [Display Chart] 5 input genes in category / 200 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0023524 Leukoencephalopathy, Progressive Multifocal DisGeNET BeFree 7.659E-9 1.532E-6 9.004E-6 1.532E-6 4 103
2 C0752125 Spinocerebellar Ataxia Type 7 DisGeNET Curated 1.613E-7 1.142E-5 6.715E-5 3.226E-5 3 42
3 C2745900 Promyelocytic leukemia DisGeNET BeFree 2.205E-7 1.142E-5 6.715E-5 4.410E-5 4 237
4 C0033587 Prosthesis Loosening DisGeNET BeFree 2.285E-7 1.142E-5 6.715E-5 4.569E-5 2 3
5 C0010823 Cytomegalovirus Infections DisGeNET Curated 3.504E-7 1.402E-5 8.239E-5 7.008E-5 4 266
6 C3697269 15q24 Microdeletion DisGeNET Curated 7.614E-7 2.538E-5 1.492E-4 1.523E-4 2 5
7 C0004779 Basal Cell Nevus Syndrome DisGeNET Curated 7.500E-5 2.143E-3 1.260E-2 1.500E-2 2 45
8 C0013371 Shigella Infections DisGeNET BeFree 1.621E-4 4.052E-3 2.382E-2 3.242E-2 2 66
9 C0023487 Acute Promyelocytic Leukemia DisGeNET Curated 2.292E-4 4.114E-3 2.418E-2 4.584E-2 3 468
10 C0035369 Retroviridae Infections DisGeNET BeFree 2.820E-4 4.114E-3 2.418E-2
5.639E-2
 2 87
11 C4022143 Unilateral cleft palate DisGeNET Curated 3.085E-4 4.114E-3 2.418E-2
6.171E-2
 1 1
12 C0349675 Hypergranular promyelocytic leukemia DisGeNET BeFree 3.085E-4 4.114E-3 2.418E-2
6.171E-2
 1 1
13 C1389273 Lesions in the basal ganglia DisGeNET BeFree 3.085E-4 4.114E-3 2.418E-2
6.171E-2
 1 1
14 cv:C1866070 Orofacial cleft 10 Clinical Variations 3.085E-4 4.114E-3 2.418E-2
6.171E-2
 1 1
15 C1866070 OROFACIAL CLEFT 10 DisGeNET Curated 3.085E-4 4.114E-3 2.418E-2
6.171E-2
 1 1
16 C0023462 Acute Megakaryocytic Leukemias DisGeNET Curated 5.539E-4 6.856E-3 4.030E-2
1.108E-1
 2 122
17 C1514915 Retinal Hemangioblastoma DisGeNET Curated 6.170E-4 6.856E-3 4.030E-2
1.234E-1
 1 2
18 C0392006 Unilateral cleft lip DisGeNET Curated 6.170E-4 6.856E-3 4.030E-2
1.234E-1
 1 2
19 C0338451 Frontotemporal dementia DisGeNET Curated 7.389E-4 7.778E-3 4.572E-2
1.478E-1
 2 141
20 C1832903 MIGRAINE, SPORADIC HEMIPLEGIC DisGeNET BeFree 9.254E-4 8.813E-3
5.181E-2
1.851E-1
 1 3
21 C1863843 Neuronal intranuclear inclusion disease DisGeNET BeFree 9.254E-4 8.813E-3
5.181E-2
1.851E-1
 1 3
22 C0279625 adult acute promyelocytic leukemia (M3) DisGeNET BeFree 1.234E-3 1.028E-2
6.043E-2
2.467E-1
 1 4
23 C0279821 metastatic pheochromocytoma DisGeNET BeFree 1.234E-3 1.028E-2
6.043E-2
2.467E-1
 1 4
24 C0265490 Trisomy 22 DisGeNET BeFree 1.234E-3 1.028E-2
6.043E-2
2.467E-1
 1 4
25 C0393799 Miller Fisher Syndrome DisGeNET BeFree 1.542E-3 1.234E-2
7.251E-2
3.084E-1
 1 5
26 C0278952 Nasopharyngeal cancer recurrent DisGeNET BeFree 1.850E-3 1.370E-2
8.056E-2
3.700E-1
 1 6
27 C1844830 CLEFT PALATE, X-LINKED DisGeNET Curated 1.850E-3 1.370E-2
8.056E-2
3.700E-1
 1 6
28 C0027022 Myeloproliferative disease DisGeNET Curated 2.372E-3 1.541E-2
9.060E-2
4.744E-1
 2 254
29 C0030326 Panniculitis DisGeNET Curated 2.466E-3 1.541E-2
9.060E-2
4.932E-1
 1 8
30 C1837217 Cleft lip, isolated DisGeNET BeFree 2.466E-3 1.541E-2
9.060E-2
4.932E-1
 1 8
31 C0268274 Gangliosidoses, GM2 DisGeNET BeFree 2.466E-3 1.541E-2
9.060E-2
4.932E-1
 1 8
32 C1838062 EPILEPSY, LATERAL TEMPORAL LOBE, AUTOSOMAL DOMINANT DisGeNET Curated 2.466E-3 1.541E-2
9.060E-2
4.932E-1
 1 8
33 C0030422 Extra-Adrenal Paraganglioma DisGeNET BeFree 3.082E-3 1.868E-2
1.098E-1
6.164E-1
 1 10
34 C0206042 Fatal Familial Insomnia DisGeNET Curated 3.390E-3 1.994E-2
1.172E-1
6.780E-1
 1 11
35 C0003537 Aphasia DisGeNET Curated 4.005E-3 2.270E-2
1.334E-1
8.010E-1
 1 13
36 C0271694 Familial partial lipodystrophy DisGeNET Curated 4.313E-3 2.270E-2
1.334E-1
8.625E-1
 1 14
37 C3179349 Gastrointestinal Stromal Sarcoma DisGeNET BeFree 4.313E-3 2.270E-2
1.334E-1
8.625E-1
 1 14
38 C1708349 Hereditary Diffuse Gastric Cancer DisGeNET Curated 4.313E-3 2.270E-2
1.334E-1
8.625E-1
 1 14
39 C0268164 Primary hyperoxaluria, type I DisGeNET Curated 4.620E-3 2.369E-2
1.393E-1
9.240E-1
 1 15
40 C0950124 Papillomavirus Infections DisGeNET Curated 4.928E-3 2.404E-2
1.413E-1
9.855E-1
 1 16
41 C0026998 Acute Myeloid Leukemia, M1 DisGeNET Curated 4.928E-3 2.404E-2
1.413E-1
9.855E-1
 1 16
42 C0262401 Carcinoma of ampulla of Vater DisGeNET BeFree 5.849E-3 2.604E-2
1.531E-1
1.000E0
 1 19
43 C1845055 ALPHA-THALASSEMIA/MENTAL RETARDATION SYNDROME, NONDELETION TYPE, X-LINKED DisGeNET Curated 6.156E-3 2.604E-2
1.531E-1
1.000E0
 1 20
44 C0085183 Neoplasms, Second Primary DisGeNET Curated 6.156E-3 2.604E-2
1.531E-1
1.000E0
 1 20
45 C3146254 Stage III Colon Cancer AJCC v7 DisGeNET BeFree 6.464E-3 2.604E-2
1.531E-1
1.000E0
 1 21
46 C1510420 Cavitation DisGeNET BeFree 6.464E-3 2.604E-2
1.531E-1
1.000E0
 1 21
47 C0878544 Cardiomyopathies DisGeNET Curated 6.752E-3 2.604E-2
1.531E-1
1.000E0
 2 433
48 C4011788 Behavioral variant of frontotemporal dementia DisGeNET Curated 6.770E-3 2.604E-2
1.531E-1
1.000E0
 1 22
49 C4280619 Missing more than six teeth DisGeNET Curated 6.770E-3 2.604E-2
1.531E-1
1.000E0
 1 22
50 C0278480 Stage III Colon Cancer DisGeNET BeFree 6.770E-3 2.604E-2
1.531E-1
1.000E0
 1 22
Show 45 more annotations