|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
1
|
15024025
|
Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins.
|
Pubmed
|
1.529E-12
|
9.632E-10
|
6.765E-9
|
9.632E-10
|
4
|
19
|
2
|
21031555
|
Expression pattern of membrane-associated guanylate kinases in interneurons of the visual cortex.
|
Pubmed
|
1.508E-11
|
3.166E-9
|
2.224E-8
|
9.499E-9
|
3
|
4
|
3
|
23201973
|
Synaptic scaffold evolution generated components of vertebrate cognitive complexity.
|
Pubmed
|
1.508E-11
|
3.166E-9
|
2.224E-8
|
9.499E-9
|
3
|
4
|
4
|
11134026
|
Sema4c, a transmembrane semaphorin, interacts with a post-synaptic density protein, PSD-95.
|
Pubmed
|
3.769E-11
|
3.958E-9
|
2.780E-8
|
2.375E-8
|
3
|
5
|
5
|
15317815
|
PSD-95 and Lin-7b interact with acid-sensing ion channel-3 and have opposite effects on H+- gated current.
|
Pubmed
|
3.769E-11
|
3.958E-9
|
2.780E-8
|
2.375E-8
|
3
|
5
|
6
|
12713445
|
Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.
|
Pubmed
|
3.769E-11
|
3.958E-9
|
2.780E-8
|
2.375E-8
|
3
|
5
|
7
|
11274188
|
Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.
|
Pubmed
|
7.538E-11
|
4.749E-9
|
3.335E-8
|
4.749E-8
|
3
|
6
|
8
|
12070168
|
Selective binding of synapse-associated protein 97 to GluR-A alpha-amino-5-hydroxy-3-methyl-4-isoxazole propionate receptor subunit is determined by a novel sequence motif.
|
Pubmed
|
7.538E-11
|
4.749E-9
|
3.335E-8
|
4.749E-8
|
3
|
6
|
9
|
19118189
|
Preso, a novel PSD-95-interacting FERM and PDZ domain protein that regulates dendritic spine morphogenesis.
|
Pubmed
|
7.538E-11
|
4.749E-9
|
3.335E-8
|
4.749E-8
|
3
|
6
|
10
|
11572861
|
Guanylyl cyclase/PSD-95 interaction: targeting of the nitric oxide-sensitive alpha2beta1 guanylyl cyclase to synaptic membranes.
|
Pubmed
|
7.538E-11
|
4.749E-9
|
3.335E-8
|
4.749E-8
|
3
|
6
|
11
|
11997254
|
Inward rectifier K+ channel Kir2.3 is localized at the postsynaptic membrane of excitatory synapses.
|
Pubmed
|
1.319E-10
|
6.925E-9
|
4.864E-8
|
8.309E-8
|
3
|
7
|
12
|
9753324
|
A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain.
|
Pubmed
|
1.319E-10
|
6.925E-9
|
4.864E-8
|
8.309E-8
|
3
|
7
|
13
|
12351654
|
Identification of multiple binding partners for the amino-terminal domain of synapse-associated protein 97.
|
Pubmed
|
2.110E-10
|
9.496E-9
|
6.670E-8
|
1.329E-7
|
3
|
8
|
14
|
16316992
|
Proteomic analysis of beta1-adrenergic receptor interactions with PDZ scaffold proteins.
|
Pubmed
|
2.110E-10
|
9.496E-9
|
6.670E-8
|
1.329E-7
|
3
|
8
|
15
|
17938206
|
The nuclear RhoA exchange factor Net1 interacts with proteins of the Dlg family, affects their localization, and influences their tumor suppressor activity.
|
Pubmed
|
3.165E-10
|
1.329E-8
|
9.337E-8
|
1.994E-7
|
3
|
9
|
16
|
21119615
|
DGKι regulates presynaptic release during mGluR-dependent LTD.
|
Pubmed
|
6.216E-10
|
2.448E-8
|
1.719E-7
|
3.916E-7
|
3
|
11
|
17
|
16980967
|
NGL family PSD-95-interacting adhesion molecules regulate excitatory synapse formation.
|
Pubmed
|
8.287E-10
|
3.071E-8
|
2.157E-7
|
5.221E-7
|
3
|
12
|
18
|
21920314
|
Dlg3 trafficking and apical tight junction formation is regulated by nedd4 and nedd4-2 e3Â ubiquitin ligases.
|
Pubmed
|
1.371E-9
|
4.798E-8
|
3.370E-7
|
8.637E-7
|
3
|
14
|
19
|
19455133
|
Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins.
|
Pubmed
|
3.072E-9
|
1.019E-7
|
7.155E-7
|
1.936E-6
|
3
|
18
|
20
|
27480238
|
SALM4 suppresses excitatory synapse development by cis-inhibiting trans-synaptic SALM3-LAR adhesion.
|
Pubmed
|
7.617E-9
|
2.285E-7
|
1.605E-6
|
4.799E-6
|
3
|
24
|
21
|
16637659
|
Uncovering quantitative protein interaction networks for mouse PDZ domains using protein microarrays.
|
Pubmed
|
7.617E-9
|
2.285E-7
|
1.605E-6
|
4.799E-6
|
3
|
24
|
22
|
18618587
|
Cloning and characterization of E-dlg, a novel splice variant of mouse homologue of the Drosophila discs large tumor suppressor binds preferentially to SAP102.
|
Pubmed
|
2.879E-8
|
7.256E-7
|
5.096E-6
|
1.814E-5
|
2
|
2
|
23
|
27760079
|
Expression of DLG1 and DLG5 in the Intestinal Epithelium of Patients with CD.
|
Pubmed
|
2.879E-8
|
7.256E-7
|
5.096E-6
|
1.814E-5
|
2
|
2
|
24
|
17267502
|
Structures of a human papillomavirus (HPV) E6 polypeptide bound to MAGUK proteins: mechanisms of targeting tumor suppressors by a high-risk HPV oncoprotein.
|
Pubmed
|
2.879E-8
|
7.256E-7
|
5.096E-6
|
1.814E-5
|
2
|
2
|
25
|
12444549
|
Chimaeric HPV E6 proteins allow dissection of the proteolytic pathways regulating different E6 cellular target proteins.
|
Pubmed
|
2.879E-8
|
7.256E-7
|
5.096E-6
|
1.814E-5
|
2
|
2
|
26
|
21489588
|
Stabilization of HPV16 E6 protein by PDZ proteins, and potential implications for genome maintenance.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
27
|
11571640
|
HPV E6 and MAGUK protein interactions: determination of the molecular basis for specific protein recognition and degradation.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
28
|
12175853
|
Compartmentalized NRG signaling and PDZ domain-containing proteins in synapse structure and function.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
29
|
28077487
|
Calcium-permeable AMPA receptors and silent synapses in cocaine-conditioned place preference.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
30
|
23486974
|
Postsynaptic density scaffold SAP102 regulates cortical synapse development through EphB and PAK signaling pathway.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
31
|
9677374
|
SAP97 is associated with the alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor GluR1 subunit.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
32
|
25268382
|
Trans-homophilic interaction of CADM1 activates PI3K by forming a complex with MAGuK-family proteins MPP3 and Dlg.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
33
|
17046693
|
Synapse-specific and developmentally regulated targeting of AMPA receptors by a family of MAGUK scaffolding proteins.
|
Pubmed
|
8.637E-8
|
1.649E-6
|
1.158E-5
|
5.441E-5
|
2
|
3
|
34
|
22745667
|
Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.
|
Pubmed
|
1.041E-7
|
1.928E-6
|
1.354E-5
|
6.556E-5
|
3
|
56
|
35
|
12097473
|
Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins.
|
Pubmed
|
1.727E-7
|
2.864E-6
|
2.011E-5
|
1.088E-4
|
2
|
4
|
36
|
19586902
|
Interaction of the RhoA exchange factor Net1 with discs large homolog 1 protects it from proteasome-mediated degradation and potentiates Net1 activity.
|
Pubmed
|
1.727E-7
|
2.864E-6
|
2.011E-5
|
1.088E-4
|
2
|
4
|
37
|
10595517
|
Cypin: a cytosolic regulator of PSD-95 postsynaptic targeting.
|
Pubmed
|
1.727E-7
|
2.864E-6
|
2.011E-5
|
1.088E-4
|
2
|
4
|
38
|
16473877
|
Ggamma13 interacts with PDZ domain-containing proteins.
|
Pubmed
|
1.727E-7
|
2.864E-6
|
2.011E-5
|
1.088E-4
|
2
|
4
|
39
|
9786987
|
Localization of postsynaptic density-93 to dendritic microtubules and interaction with microtubule-associated protein 1A.
|
Pubmed
|
2.879E-7
|
4.217E-6
|
2.962E-5
|
1.814E-4
|
2
|
5
|
40
|
9808460
|
SAP90 binds and clusters kainate receptors causing incomplete desensitization.
|
Pubmed
|
2.879E-7
|
4.217E-6
|
2.962E-5
|
1.814E-4
|
2
|
5
|
41
|
17237226
|
The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions.
|
Pubmed
|
2.879E-7
|
4.217E-6
|
2.962E-5
|
1.814E-4
|
2
|
5
|
42
|
10725395
|
The neuregulin receptor ErbB-4 interacts with PDZ-containing proteins at neuronal synapses.
|
Pubmed
|
2.879E-7
|
4.217E-6
|
2.962E-5
|
1.814E-4
|
2
|
5
|
43
|
16482544
|
Involvement of a cellular ubiquitin-protein ligase E6AP in the ubiquitin-mediated degradation of extensive substrates of high-risk human papillomavirus E6.
|
Pubmed
|
2.879E-7
|
4.217E-6
|
2.962E-5
|
1.814E-4
|
2
|
5
|
44
|
10862698
|
Proteomic analysis of NMDA receptor-adhesion protein signaling complexes.
|
Pubmed
|
3.442E-7
|
4.928E-6
|
3.461E-5
|
2.168E-4
|
3
|
83
|
45
|
16495444
|
A novel family of adhesion-like molecules that interacts with the NMDA receptor.
|
Pubmed
|
6.044E-7
|
7.933E-6
|
5.572E-5
|
3.808E-4
|
2
|
7
|
46
|
19243221
|
Neto1 is a novel CUB-domain NMDA receptor-interacting protein required for synaptic plasticity and learning.
|
Pubmed
|
6.044E-7
|
7.933E-6
|
5.572E-5
|
3.808E-4
|
2
|
7
|
47
|
7477295
|
Clustering of Shaker-type K+ channels by interaction with a family of membrane-associated guanylate kinases.
|
Pubmed
|
6.044E-7
|
7.933E-6
|
5.572E-5
|
3.808E-4
|
2
|
7
|
48
|
9115257
|
SAPAPs. A family of PSD-95/SAP90-associated proteins localized at postsynaptic density.
|
Pubmed
|
6.044E-7
|
7.933E-6
|
5.572E-5
|
3.808E-4
|
2
|
7
|
49
|
14960569
|
A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels.
|
Pubmed
|
1.036E-6
|
1.231E-5
|
8.649E-5
|
6.526E-4
|
2
|
9
|
50
|
24498314
|
C-terminal interactors of the AMPA receptor auxiliary subunit Shisa9.
|
Pubmed
|
1.036E-6
|
1.231E-5
|
8.649E-5
|
6.526E-4
|
2
|
9
|