Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc429_6, positive side

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1: GO: Molecular Function [Display Chart] 6 input genes in category / 40 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0047888 fatty acid peroxidase activity 3.215E-4 5.144E-3 2.201E-2 1.286E-2 1 1
2 GO:0005200 structural constituent of cytoskeleton 5.086E-4 5.144E-3 2.201E-2 2.034E-2 2 110
3 GO:0016708 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor 6.430E-4 5.144E-3 2.201E-2 2.572E-2 1 2
4 GO:0008941 nitric oxide dioxygenase activity 6.430E-4 5.144E-3 2.201E-2 2.572E-2 1 2
5 GO:0035402 histone kinase activity (H3-T11 specific) 6.430E-4 5.144E-3 2.201E-2 2.572E-2 1 2
6 GO:0004096 catalase activity 9.643E-4 6.429E-3 2.751E-2 3.857E-2 1 3
7 GO:0035184 histone threonine kinase activity 2.249E-3 1.285E-2
5.498E-2
8.995E-2
 1 7
8 GO:0005344 oxygen carrier activity 4.494E-3 2.054E-2
8.787E-2
1.797E-1
 1 14
9 GO:0019215 intermediate filament binding 5.134E-3 2.054E-2
8.787E-2
2.054E-1
 1 16
10 GO:0017049 GTP-Rho binding 5.134E-3 2.054E-2
8.787E-2
2.054E-1
 1 16
11 GO:0035173 histone kinase activity 6.094E-3 2.216E-2
9.482E-2
2.438E-1
 1 19
12 GO:0004697 protein kinase C activity 7.693E-3 2.564E-2
1.097E-1
3.077E-1
 1 24
13 GO:0050681 androgen receptor binding 1.311E-2 3.755E-2
1.606E-1
5.245E-1
 1 41
14 GO:0048365 Rac GTPase binding 1.343E-2 3.755E-2
1.606E-1
5.372E-1
 1 42
15 GO:0004601 peroxidase activity 1.438E-2 3.755E-2
1.606E-1
5.753E-1
 1 45
16 GO:0016684 oxidoreductase activity, acting on peroxide as acceptor 1.502E-2 3.755E-2
1.606E-1
6.008E-1
 1 47
17 GO:0019825 oxygen binding 1.629E-2 3.831E-2
1.639E-1
6.515E-1
 1 51
18 GO:0030374 nuclear receptor transcription coactivator activity 1.724E-2 3.831E-2
1.639E-1
6.896E-1
 1 54
19 GO:0005080 protein kinase C binding 1.977E-2 4.163E-2
1.781E-1
7.909E-1
 1 62
20 GO:0016209 antioxidant activity 2.419E-2 4.838E-2
2.070E-1
9.677E-1
 1 76
21 GO:0017048 Rho GTPase binding 2.765E-2 4.973E-2
2.128E-1
1.000E0
 1 87
22 GO:0035258 steroid hormone receptor binding 2.828E-2 4.973E-2
2.128E-1
1.000E0
 1 89
23 GO:0051213 dioxygenase activity 2.859E-2 4.973E-2
2.128E-1
1.000E0
 1 90
Show 18 more annotations

2: GO: Biological Process [Display Chart] 6 input genes in category / 200 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0045104 intermediate filament cytoskeleton organization 4.445E-10 4.868E-8 2.861E-7 8.890E-8 4 45
2 GO:0045103 intermediate filament-based process 4.868E-10 4.868E-8 2.861E-7 9.736E-8 4 46
3 GO:0045109 intermediate filament organization 1.812E-5 1.208E-3 7.099E-3 3.623E-3 2 21
4 GO:0030842 regulation of intermediate filament depolymerization 3.222E-4 8.055E-3 4.734E-2
6.444E-2
 1 1
5 GO:0030844 positive regulation of intermediate filament depolymerization 3.222E-4 8.055E-3 4.734E-2
6.444E-2
 1 1
6 GO:0010625 positive regulation of Schwann cell proliferation 3.222E-4 8.055E-3 4.734E-2
6.444E-2
 1 1
7 GO:0045106 intermediate filament depolymerization 3.222E-4 8.055E-3 4.734E-2
6.444E-2
 1 1
8 GO:0045108 regulation of intermediate filament polymerization or depolymerization 3.222E-4 8.055E-3 4.734E-2
6.444E-2
 1 1
9 GO:0035407 histone H3-T11 phosphorylation 6.443E-4 1.171E-2
6.886E-2
1.289E-1
 1 2
10 GO:2000490 negative regulation of hepatic stellate cell activation 6.443E-4 1.171E-2
6.886E-2
1.289E-1
 1 2
11 GO:0045105 intermediate filament polymerization or depolymerization 6.443E-4 1.171E-2
6.886E-2
1.289E-1
 1 2
12 GO:0033693 neurofilament bundle assembly 9.663E-4 1.610E-2
9.466E-2
1.933E-1
 1 3
13 GO:0050866 negative regulation of cell activation 1.344E-3 2.067E-2
1.215E-1
2.687E-1
 2 179
14 GO:0045110 intermediate filament bundle assembly 1.932E-3 2.575E-2
1.514E-1
3.864E-1
 1 6
15 GO:0010624 regulation of Schwann cell proliferation 1.932E-3 2.575E-2
1.514E-1
3.864E-1
 1 6
16 GO:0035405 histone-threonine phosphorylation 2.253E-3 2.575E-2
1.514E-1
4.507E-1
 1 7
17 GO:1904714 regulation of chaperone-mediated autophagy 2.253E-3 2.575E-2
1.514E-1
4.507E-1
 1 7
18 GO:2000489 regulation of hepatic stellate cell activation 2.575E-3 2.575E-2
1.514E-1
5.150E-1
 1 8
19 GO:0010764 negative regulation of fibroblast migration 2.575E-3 2.575E-2
1.514E-1
5.150E-1
 1 8
20 GO:0014010 Schwann cell proliferation 2.575E-3 2.575E-2
1.514E-1
5.150E-1
 1 8
21 GO:0060052 neurofilament cytoskeleton organization 3.218E-3 2.682E-2
1.576E-1
6.436E-1
 1 10
22 GO:0060020 Bergmann glial cell differentiation 3.218E-3 2.682E-2
1.576E-1
6.436E-1
 1 10
23 GO:0061684 chaperone-mediated autophagy 3.218E-3 2.682E-2
1.576E-1
6.436E-1
 1 10
24 GO:0035733 hepatic stellate cell activation 3.218E-3 2.682E-2
1.576E-1
6.436E-1
 1 10
25 GO:0032966 negative regulation of collagen biosynthetic process 3.539E-3 2.723E-2
1.600E-1
7.079E-1
 1 11
26 GO:0002634 regulation of germinal center formation 3.539E-3 2.723E-2
1.600E-1
7.079E-1
 1 11
27 GO:0010713 negative regulation of collagen metabolic process 3.860E-3 2.860E-2
1.681E-1
7.721E-1
 1 12
28 GO:0072537 fibroblast activation 4.182E-3 2.987E-2
1.756E-1
8.363E-1
 1 13
29 GO:0060252 positive regulation of glial cell proliferation 4.503E-3 3.105E-2
1.825E-1
9.005E-1
 1 14
30 GO:0015671 oxygen transport 4.824E-3 3.188E-2
1.874E-1
9.647E-1
 1 15
31 GO:0001667 ameboidal-type cell migration 4.942E-3 3.188E-2
1.874E-1
9.883E-1
 2 347
32 GO:0051580 regulation of neurotransmitter uptake 5.145E-3 3.215E-2
1.890E-1
1.000E0
 1 16
33 GO:0002467 germinal center formation 5.465E-3 3.215E-2
1.890E-1
1.000E0
 1 17
34 GO:0030889 negative regulation of B cell proliferation 5.465E-3 3.215E-2
1.890E-1
1.000E0
 1 17
35 GO:1901881 positive regulation of protein depolymerization 6.427E-3 3.673E-2
2.159E-1
1.000E0
 1 20
36 GO:0015669 gas transport 7.388E-3 3.994E-2
2.348E-1
1.000E0
 1 23
37 GO:0014002 astrocyte development 7.388E-3 3.994E-2
2.348E-1
1.000E0
 1 23
38 GO:0006972 hyperosmotic response 8.349E-3 4.229E-2
2.486E-1
1.000E0
 1 26
39 GO:0001783 B cell apoptotic process 8.669E-3 4.229E-2
2.486E-1
1.000E0
 1 27
40 GO:0043243 positive regulation of protein complex disassembly 8.669E-3 4.229E-2
2.486E-1
1.000E0
 1 27
41 GO:0060251 regulation of glial cell proliferation 8.669E-3 4.229E-2
2.486E-1
1.000E0
 1 27
42 GO:0001504 neurotransmitter uptake 8.988E-3 4.280E-2
2.516E-1
1.000E0
 1 28
43 GO:0050869 negative regulation of B cell activation 1.059E-2 4.812E-2
2.829E-1
1.000E0
 1 33
44 GO:0010762 regulation of fibroblast migration 1.059E-2 4.812E-2
2.829E-1
1.000E0
 1 33
Show 39 more annotations

3: GO: Cellular Component [Display Chart] 6 input genes in category / 25 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005882 intermediate filament 1.771E-7 4.427E-6 1.689E-5 4.427E-6 4 201
2 GO:0045111 intermediate filament cytoskeleton 3.852E-7 4.815E-6 1.837E-5 9.630E-6 4 244
3 GO:0005883 neurofilament 3.712E-6 3.093E-5 1.180E-4 9.279E-5 2 10
4 GO:0098574 cytoplasmic side of lysosomal membrane 9.441E-4 4.916E-3 1.876E-2 2.360E-2 1 3
5 GO:0097418 neurofibrillary tangle 1.573E-3 4.916E-3 1.876E-2 3.933E-2 1 5
6 GO:0045098 type III intermediate filament 1.573E-3 4.916E-3 1.876E-2 3.933E-2 1 5
7 GO:0044299 C-fiber 1.573E-3 4.916E-3 1.876E-2 3.933E-2 1 5
8 GO:0097450 astrocyte end-foot 1.573E-3 4.916E-3 1.876E-2 3.933E-2 1 5
9 GO:0097449 astrocyte projection 4.086E-3 1.135E-2 4.331E-2
1.021E-1
 1 13
10 GO:0097386 glial cell projection 5.653E-3 1.285E-2 4.903E-2
1.413E-1
 1 18
11 GO:0042622 photoreceptor outer segment membrane 5.653E-3 1.285E-2 4.903E-2
1.413E-1
 1 18
12 GO:0032154 cleavage furrow 1.533E-2 2.948E-2
1.125E-1
3.832E-1
 1 49
13 GO:0097610 cell surface furrow 1.533E-2 2.948E-2
1.125E-1
3.832E-1
 1 49
14 GO:0032153 cell division site 1.781E-2 2.969E-2
1.133E-1
4.453E-1
 1 57
15 GO:0032155 cell division site part 1.781E-2 2.969E-2
1.133E-1
4.453E-1
 1 57
16 GO:0016234 inclusion body 2.307E-2 3.605E-2
1.376E-1
5.768E-1
 1 74
17 GO:0001750 photoreceptor outer segment 2.585E-2 3.718E-2
1.419E-1
6.462E-1
 1 83
18 GO:0060170 ciliary membrane 2.677E-2 3.718E-2
1.419E-1
6.693E-1
 1 86
Show 13 more annotations

4: Human Phenotype [Display Chart] 3 input genes in category / 247 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0002483 Bulbar signs 1.795E-4 3.115E-2
1.896E-1
 4.434E-2 2 37
2 HP:0011441 Abnormality of the medulla oblongata 6.373E-4 3.115E-2
1.896E-1
1.574E-1
 1 1
3 HP:0007481 Hyperpigmented nevi 6.373E-4 3.115E-2
1.896E-1
1.574E-1
 1 1
4 HP:0100320 Rosenthal fibres 6.373E-4 3.115E-2
1.896E-1
1.574E-1
 1 1
5 HP:0010530 Palatal myoclonus 6.373E-4 3.115E-2
1.896E-1
1.574E-1
 1 1
6 HP:0002200 Pseudobulbar signs 7.639E-4 3.115E-2
1.896E-1
1.887E-1
 2 76
7 HP:0100314 Cerebral inclusion bodies 1.193E-3 3.115E-2
1.896E-1
2.948E-1
 2 95
8 HP:0007162 Diffuse demyelination of the cerebral white matter 1.274E-3 3.115E-2
1.896E-1
3.148E-1
 1 2
9 HP:0007307 Rapid neurologic deterioration 1.274E-3 3.115E-2
1.896E-1
3.148E-1
 1 2
10 HP:0001618 Dysphonia 1.485E-3 3.115E-2
1.896E-1
3.668E-1
 2 106
11 HP:0000712 Emotional lability 1.513E-3 3.115E-2
1.896E-1
3.738E-1
 2 107
12 HP:0002127 Abnormal upper motor neuron morphology 1.513E-3 3.115E-2
1.896E-1
3.738E-1
 2 107
13 HP:0002459 Dysautonomia 1.777E-3 3.377E-2
2.056E-1
4.390E-1
 2 116
14 HP:0002383 Encephalitis 2.264E-3 3.701E-2
2.253E-1
5.593E-1
 2 131
15 HP:0002382 Variable mental retardation 2.264E-3 3.701E-2
2.253E-1
5.593E-1
 2 131
16 HP:0100247 Recurrent singultus 2.548E-3 3.701E-2
2.253E-1
6.293E-1
 1 4
17 HP:0010535 Sleep apnea 2.584E-3 3.701E-2
2.253E-1
6.382E-1
 2 140
18 HP:0001325 Hypoglycemic coma 2.809E-3 3.701E-2
2.253E-1
6.937E-1
 2 146
19 HP:0001296 Mood alterations 2.847E-3 3.701E-2
2.253E-1
7.032E-1
 2 147
20 HP:0002072 Chorea 4.023E-3 4.881E-2
2.972E-1
9.936E-1
 2 175
21 HP:0002363 Abnormality of brainstem morphology 4.301E-3 4.881E-2
2.972E-1
1.000E0
 2 181
22 HP:0012332 Abnormal autonomic nervous system physiology 4.348E-3 4.881E-2
2.972E-1
1.000E0
 2 182
Show 17 more annotations

5: Mouse Phenotype [Display Chart] 4 input genes in category / 179 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 6 input genes in category / 41 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR006821 Intermed filament DNA-bd InterPro 6.385E-10 1.309E-8 5.632E-8 2.618E-8 3 7
2 PF04732 Filament head Pfam 6.385E-10 1.309E-8 5.632E-8 2.618E-8 3 7
3 IPR018039 Intermediate filament CS InterPro 1.732E-9 2.161E-8 9.300E-8 7.103E-8 4 63
4 SM01391 Filament SMART 2.824E-9 2.161E-8 9.300E-8 1.158E-7 4 71
5 PS00226 IF PROSITE 2.990E-9 2.161E-8 9.300E-8 1.226E-7 4 72
6 PF00038 Filament Pfam 3.163E-9 2.161E-8 9.300E-8 1.297E-7 4 73
7 IPR001664 IF InterPro 3.727E-9 2.183E-8 9.393E-8 1.528E-7 4 76
8 IPR002957 Keratin I InterPro 2.405E-7 1.233E-6 5.304E-6 9.862E-6 3 44
9 IPR027700 PRPH/Plasticin InterPro 3.203E-4 1.010E-3 4.346E-3 1.313E-2 1 1
10 IPR031211 Nestin InterPro 3.203E-4 1.010E-3 4.346E-3 1.313E-2 1 1
11 IPR027697 NF-M InterPro 3.203E-4 1.010E-3 4.346E-3 1.313E-2 1 1
12 IPR027701 GFAP InterPro 3.203E-4 1.010E-3 4.346E-3 1.313E-2 1 1
13 IPR013314 Globin lamprey/hagfish InterPro 3.203E-4 1.010E-3 4.346E-3 1.313E-2 1 1
14 IPR002335 Myoglobin InterPro 6.404E-4 1.876E-3 8.070E-3 2.626E-2 1 2
15 1.10.287.160 - Gene3D 1.600E-3 4.374E-3 1.882E-2
6.562E-2
 1 5
16 SM00742 Hr1 SMART 2.240E-3 5.740E-3 2.470E-2
9.184E-2
 1 7
17 PF02185 HR1 Pfam 2.560E-3 6.173E-3 2.656E-2
1.049E-1
 1 8
18 PS01033 GLOBIN PROSITE 3.837E-3 7.747E-3 3.333E-2
1.573E-1
 1 12
19 IPR000971 Globin InterPro 3.837E-3 7.747E-3 3.333E-2
1.573E-1
 1 12
20 PF00042 Globin Pfam 3.837E-3 7.747E-3 3.333E-2
1.573E-1
 1 12
21 IPR012292 Globin/Proto InterPro 4.157E-3 7.747E-3 3.333E-2
1.704E-1
 1 13
22 1.10.490.10 - Gene3D 4.157E-3 7.747E-3 3.333E-2
1.704E-1
 1 13
23 IPR009050 Globin-like InterPro 5.114E-3 9.116E-3 3.923E-2
2.097E-1
 1 16
24 IPR011072 HR1 rho-bd InterPro 7.981E-3 1.363E-2
5.867E-2
3.272E-1
 1 25
25 IPR017892 Pkinase C InterPro 1.179E-2 1.934E-2
8.322E-2
4.835E-1
 1 37
26 PF00433 Pkinase C Pfam 1.338E-2 2.110E-2
9.077E-2
5.485E-1
 1 42
27 PS51285 AGC KINASE CTER PROSITE 1.780E-2 2.517E-2
1.083E-1
7.299E-1
 1 56
28 IPR000961 AGC-kinase C InterPro 1.780E-2 2.517E-2
1.083E-1
7.299E-1
 1 56
29 SM00133 S TK X SMART 1.780E-2 2.517E-2
1.083E-1
7.299E-1
 1 56
Show 24 more annotations

7: Pathway [Display Chart] 5 input genes in category / 21 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 83099 Amyotrophic lateral sclerosis (ALS) BioSystems: KEGG 1.632E-4 3.428E-3 1.250E-2 3.428E-3 2 51
2 138043 Signaling mediated by p38-gamma and p38-delta BioSystems: Pathway Interaction Database 4.411E-3 2.524E-2
9.202E-2
9.262E-2
 1 11
3 1270117 eNOS activation BioSystems: REACTOME 4.811E-3 2.524E-2
9.202E-2
1.010E-1
 1 12
4 PW:0000016 amyotrophic lateral sclerosis disease Pathway Ontology 6.011E-3 2.524E-2
9.202E-2
1.262E-1
 1 15
5 M15347 Protein Kinase A at the Centrosome MSigDB C2 BIOCARTA (v6.0) 6.011E-3 2.524E-2
9.202E-2
1.262E-1
 1 15
6 1270115 Metabolism of nitric oxide BioSystems: REACTOME 8.806E-3 2.625E-2
9.571E-2
1.849E-1
 1 22
7 1270116 eNOS activation and regulation BioSystems: REACTOME 8.806E-3 2.625E-2
9.571E-2
1.849E-1
 1 22
8 1269499 Nuclear signaling by ERBB4 BioSystems: REACTOME 1.000E-2 2.625E-2
9.571E-2
2.100E-1
 1 25
9 M7014 PKC-catalyzed phosphorylation of inhibitory phosphoprotein of myosin phosphatase MSigDB C2 BIOCARTA (v6.0) 1.239E-2 2.891E-2
1.054E-1
2.602E-1
 1 31
10 169356 RhoA signaling pathway BioSystems: Pathway Interaction Database 1.636E-2 3.275E-2
1.194E-1
3.436E-1
 1 41
11 1269496 Signaling by ERBB4 BioSystems: REACTOME 1.715E-2 3.275E-2
1.194E-1
3.602E-1
 1 43
12 138027 Regulation of Androgen receptor activity BioSystems: Pathway Interaction Database 1.992E-2 3.486E-2
1.271E-1
4.184E-1
 1 50
13 P00042 Muscarinic acetylcholine receptor 1 and 3 signaling pathway PantherDB 2.190E-2 3.537E-2
1.289E-1
4.598E-1
 1 55
14 P00003 Alzheimer disease-amyloid secretase pathway PantherDB 2.584E-2 3.782E-2
1.379E-1
5.426E-1
 1 65
15 1269513 Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 BioSystems: REACTOME 2.702E-2 3.782E-2
1.379E-1
5.674E-1
 1 68
16 375172 Salmonella infection BioSystems: KEGG 3.407E-2 4.472E-2
1.630E-1
7.155E-1
 1 86
17 1269512 RHO GTPases activate PKNs BioSystems: REACTOME 3.719E-2 4.594E-2
1.675E-1
7.810E-1
 1 94
Show 12 more annotations

8: Pubmed [Display Chart] 6 input genes in category / 1915 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 25178519 Immunohistochemical analysis of GFAP-δ and nestin in cerebral astrocytomas. Pubmed 2.057E-8 3.939E-5 3.204E-4 3.939E-5 2 2
2 29196434 Type III Intermediate Filaments Desmin, Glial Fibrillary Acidic Protein (GFAP), Vimentin, and Peripherin. Pubmed 1.234E-7 7.875E-5 6.407E-4 2.363E-4 2 4
3 27016413 Neuropathy correlated with imbalanced Foxp3/IL-17 in bone marrow microenvironment of patients with acute myeloid leukemia. Pubmed 2.056E-7 7.875E-5 6.407E-4 3.938E-4 2 5
4 12403814 Myosin Va binding to neurofilaments is essential for correct myosin Va distribution and transport and neurofilament density. Pubmed 2.056E-7 7.875E-5 6.407E-4 3.938E-4 2 5
5 28512739 Normal development of spinal axons in early embryo stages and posterior locomotor function is independent of GAL-1. Pubmed 2.056E-7 7.875E-5 6.407E-4 3.938E-4 2 5
6 7720210 Nestin mRNA expression correlates with the central nervous system progenitor cell state in many, but not all, regions of developing central nervous system. Pubmed 3.084E-7 9.844E-5 8.008E-4 5.906E-4 2 6
7 8565847 Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Pubmed 5.756E-7 1.575E-4 1.281E-3 1.102E-3 2 8
8 14598259 Genetic background modifies intestinal pseudo-obstruction and the expression of a reporter gene in Hox11L1-/- mice. Pubmed 7.400E-7 1.575E-4 1.281E-3 1.417E-3 2 9
9 24582971 Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells. Pubmed 7.400E-7 1.575E-4 1.281E-3 1.417E-3 2 9
10 11044402 Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. Pubmed 1.130E-6 2.165E-4 1.761E-3 2.165E-3 2 11
11 20058045 Delta/notch-like EGF-related receptor (DNER) is expressed in hair cells and neurons in the developing and adult mouse inner ear. Pubmed 2.158E-6 3.756E-4 3.056E-3 4.132E-3 2 15
12 21068328 Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. Pubmed 2.794E-6 4.459E-4 3.627E-3 5.351E-3 2 17
13 17537790 Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Pubmed 4.744E-6 6.165E-4 5.015E-3 9.085E-3 2 22
14 19034380 Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. Pubmed 1.366E-5 6.165E-4 5.015E-3 2.617E-2 2 37
15 20471030 Proteome analysis of the thalamus and cerebrospinal fluid reveals glycolysis dysfunction and potential biomarkers candidates for schizophrenia. Pubmed 2.411E-5 6.165E-4 5.015E-3 4.617E-2 2 49
16 22360420 Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration. Pubmed 9.513E-5 6.165E-4 5.015E-3
1.822E-1
 2 97
17 17203480 Identification and characterization of GFAPkappa, a novel glial fibrillary acidic protein isoform. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
18 17703343 A novel mutation in the GFAP gene in a familial adult onset Alexander disease. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
19 21917775 GFAP mutations, age at onset, and clinical subtypes in Alexander disease. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
20 23826164 Genetic background affects human glial fibrillary acidic protein promoter activity. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
21 14753450 A role of glial fibrillary acidic protein in hippocampal degeneration after cerebral trauma or kainate-induced seizure. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
22 22187705 Clinicopathological correlations of nestin expression in surgically resectable pancreatic cancer including an analysis of perineural invasion. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
23 17038307 Synergistic effects of the SAPK/JNK and the proteasome pathway on glial fibrillary acidic protein (GFAP) accumulation in Alexander disease. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
24 22488673 Splice site, frameshift, and chimeric GFAP mutations in Alexander disease. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
25 10377352 Developmental requirement of gp130 signaling in neuronal survival and astrocyte differentiation. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
26 21985957 Isoform-specific expression and ratio changes accompany oxidant-induced peripherin aggregation in a neuroblastoma cell line. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
27 27570826 Type II Cochlear Ganglion Neurons Do Not Drive the Olivocochlear Reflex: Re-Examination of the Cochlear Phenotype in Peripherin Knock-Out Mice. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
28 9104587 An evolutionarily conserved region in the second intron of the human nestin gene directs gene expression to CNS progenitor cells and to early neural crest cells. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
29 9422542 Experimental autoimmune encephalomyelitis in mice lacking glial fibrillary acidic protein is characterized by a more severe clinical course and an infiltrative central nervous system lesion. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
30 21248132 Genetically induced adult oligodendrocyte cell death is associated with poor myelin clearance, reduced remyelination, and axonal damage. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
31 18709437 Transgenic mice expressing the Peripherin-EGFP genomic reporter display intrinsic peripheral nervous system fluorescence. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
32 9453548 Peripherin is tyrosine-phosphorylated at its carboxyl-terminal tyrosine. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
33 18794132 Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
34 11563628 Transcription of intermediate filament genes is enhanced in focal cortical dysplasia. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
35 20849398 Glial fibrillary acidic protein mutations in adult-onset Alexander disease: clinical features observed in 12 Japanese patients. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
36 16787413 Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
37 21368556 Differential patterns of nestin and glial fibrillary acidic protein expression in mouse hippocampus during postnatal development. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
38 29970509 Comparison of Microvessel Density Using Nestin and CD34 in Colorectal Cancer. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
39 29517198 Clinical significance of nestin and its association with survival in neuroendocrine lung tumours. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
40 1847665 Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
41 10686078 Coexpression of nestin in neural and glial cells in the developing human CNS defined by a human-specific anti-nestin antibody. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
42 24296877 Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
43 12065660 Reduced number of unmyelinated sensory axons in peripherin null mice. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
44 23911257 Increased expression of glial fibrillary acidic protein in prefrontal cortex in psychotic illness. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
45 23903069 Effects of a polymorphism in the GFAP promoter on the age of onset and ambulatory disability in late-onset Alexander disease. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
46 22572237 Prognostic impact of nestin expression in resected large cell neuroendocrine carcinoma of the lung. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
47 28656248 Nestin-positive microvessel density is an independent prognostic factor in breast cancer. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
48 20669222 Inducible expression of stem cell associated intermediate filament nestin reveals an important role in glioblastoma carcinogenesis. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
49 19372295 Marked increase in cerebrospinal fluid glial fibrillar acidic protein in neuromyelitis optica: an astrocytic damage marker. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
50 15176089 Nestin promoter/enhancer directs transgene expression to precursors of adult generated periglomerular neurons. Pubmed 1.571E-4 6.165E-4 5.015E-3
3.008E-1
 1 1
Show 45 more annotations

9: Interaction [Display Chart] 6 input genes in category / 257 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:SYNC SYNC interactions 4.509E-10 1.159E-7 7.101E-7 1.159E-7 4 43
2 int:VIM VIM interactions 1.196E-8 1.536E-6 9.415E-6 3.073E-6 5 325
3 int:RSPRY1 RSPRY1 interactions 3.488E-7 2.037E-5 1.248E-4 8.965E-5 3 47
4 int:NEFM NEFM interactions 3.720E-7 2.037E-5 1.248E-4 9.561E-5 3 48
5 int:FAM167A FAM167A interactions 3.962E-7 2.037E-5 1.248E-4 1.018E-4 3 49
6 int:NES NES interactions 8.943E-7 3.831E-5 2.348E-4 2.298E-4 3 64
7 int:NEFL NEFL interactions 2.114E-6 7.763E-5 4.757E-4 5.434E-4 3 85
8 int:GOLGA2 GOLGA2 interactions 3.326E-6 1.017E-4 6.231E-4 8.547E-4 4 389
9 int:GFAP GFAP interactions 3.560E-6 1.017E-4 6.231E-4 9.150E-4 3 101
10 int:KRT15 KRT15 interactions 8.341E-6 2.144E-4 1.314E-3 2.144E-3 3 134
11 int:NEFH NEFH interactions 4.727E-5 1.104E-3 6.768E-3 1.215E-2 2 32
12 int:DES DES interactions 1.309E-4 2.788E-3 1.709E-2 3.364E-2 2 53
13 int:INA INA interactions 1.410E-4 2.788E-3 1.709E-2 3.624E-2 2 55
14 int:UBR2 UBR2 interactions 2.034E-4 3.733E-3 2.288E-2
5.227E-2
 2 66
15 int:MYO5A MYO5A interactions 3.141E-4 5.382E-3 3.298E-2
8.073E-2
 2 82
16 int:UBR1 UBR1 interactions 3.455E-4 5.549E-3 3.401E-2
8.879E-2
 2 86
17 int:LMNB1 LMNB1 interactions 7.053E-4 1.066E-2
6.534E-2
1.813E-1
 2 123
18 int:CAPN1 CAPN1 interactions 8.239E-4 1.176E-2
7.209E-2
2.117E-1
 2 133
19 int:NEUROD2 NEUROD2 interactions 1.016E-3 1.375E-2
8.426E-2
2.612E-1
 1 3
20 int:KCNMA1 KCNMA1 interactions 1.688E-3 1.892E-2
1.160E-1
4.339E-1
 2 191
21 int:SPRR2D SPRR2D interactions 1.694E-3 1.892E-2
1.160E-1
4.353E-1
 1 5
22 int:PRPH2 PRPH2 interactions 1.694E-3 1.892E-2
1.160E-1
4.353E-1
 1 5
23 int:CYGB CYGB interactions 1.694E-3 1.892E-2
1.160E-1
4.353E-1
 1 5
24 int:GAN GAN interactions 2.017E-3 2.160E-2
1.323E-1
5.183E-1
 2 209
25 int:DNASE1L1 DNASE1L1 interactions 2.370E-3 2.437E-2
1.493E-1
6.092E-1
 1 7
26 int:DIPK2A DIPK2A interactions 2.709E-3 2.526E-2
1.548E-1
6.961E-1
 1 8
27 int:GRTP1 GRTP1 interactions 2.709E-3 2.526E-2
1.548E-1
6.961E-1
 1 8
28 int:CLEC4M CLEC4M interactions 3.047E-3 2.526E-2
1.548E-1
7.830E-1
 1 9
29 int:INTS4P2 INTS4P2 interactions 3.047E-3 2.526E-2
1.548E-1
7.830E-1
 1 9
30 int:NT5DC1 NT5DC1 interactions 3.047E-3 2.526E-2
1.548E-1
7.830E-1
 1 9
31 int:ZNF282 ZNF282 interactions 3.047E-3 2.526E-2
1.548E-1
7.830E-1
 1 9
32 int:SPDL1 SPDL1 interactions 3.436E-3 2.760E-2
1.691E-1
8.831E-1
 2 274
33 int:LURAP1L LURAP1L interactions 3.723E-3 2.814E-2
1.725E-1
9.568E-1
 1 11
34 int:MICALL2 MICALL2 interactions 3.723E-3 2.814E-2
1.725E-1
9.568E-1
 1 11
35 int:KBTBD8 KBTBD8 interactions 4.061E-3 2.821E-2
1.729E-1
1.000E0
 1 12
36 int:FERD3L FERD3L interactions 4.061E-3 2.821E-2
1.729E-1
1.000E0
 1 12
37 int:PIH1D2 PIH1D2 interactions 4.061E-3 2.821E-2
1.729E-1
1.000E0
 1 12
38 int:SH3YL1 SH3YL1 interactions 4.399E-3 2.899E-2
1.776E-1
1.000E0
 1 13
39 int:DNAH14 DNAH14 interactions 4.399E-3 2.899E-2
1.776E-1
1.000E0
 1 13
40 int:PDHA1 PDHA1 interactions 4.516E-3 2.901E-2
1.778E-1
1.000E0
 2 315
41 int:RHEX RHEX interactions 5.074E-3 2.955E-2
1.811E-1
1.000E0
 1 15
42 int:CDK1 CDK1 interactions 5.363E-3 2.955E-2
1.811E-1
1.000E0
 2 344
43 int:ZNF747 ZNF747 interactions 5.411E-3 2.955E-2
1.811E-1
1.000E0
 1 16
44 int:DDI1 DDI1 interactions 5.411E-3 2.955E-2
1.811E-1
1.000E0
 1 16
45 int:ALG3 ALG3 interactions 5.411E-3 2.955E-2
1.811E-1
1.000E0
 1 16
46 int:FUOM FUOM interactions 5.411E-3 2.955E-2
1.811E-1
1.000E0
 1 16
47 int:IKBKG IKBKG interactions 5.578E-3 2.955E-2
1.811E-1
1.000E0
 2 351
48 int:FAM50B FAM50B interactions 5.749E-3 2.955E-2
1.811E-1
1.000E0
 1 17
49 int:ARHGAP10 ARHGAP10 interactions 5.749E-3 2.955E-2
1.811E-1
1.000E0
 1 17
50 int:ZFAND6 ZFAND6 interactions 5.749E-3 2.955E-2
1.811E-1
1.000E0
 1 17
Show 45 more annotations

10: Cytoband [Display Chart] 6 input genes in category / 6 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 12q12-q13 12q12-q13 1.384E-3 8.305E-3 2.035E-2 8.305E-3 1 8
2 8p21 8p21 3.457E-3 1.037E-2 2.541E-2 2.074E-2 1 20
3 17q25 17q25 6.733E-3 1.056E-2 2.586E-2 4.040E-2 1 39
4 1q23.1 1q23.1 8.109E-3 1.056E-2 2.586E-2 4.865E-2 1 47
5 19p13.12 19p13.12 8.797E-3 1.056E-2 2.586E-2
5.278E-2
 1 51
6 17q21 17q21 1.086E-2 1.086E-2 2.660E-2
6.514E-2
 1 63
Show 1 more annotation

11: Transcription Factor Binding Site [Display Chart] 4 input genes in category / 32 annotations before applied cutoff / 9770 genes in category

No results to display

12: Gene Family [Display Chart] 5 input genes in category / 3 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 610 Intermediate filaments Type III genenames.org 6.040E-7 1.359E-6 2.491E-6 1.812E-6 2 5
2 611 Intermediate filaments Type IV|Protein phosphatase 1 regulatory subunits genenames.org 9.059E-7 1.359E-6 2.491E-6 2.718E-6 2 6
3 835 C2 domain containing protein kinases genenames.org 2.745E-3 2.745E-3 5.033E-3 8.236E-3 1 10

13: Coexpression [Display Chart] 6 input genes in category / 404 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16014634-Table1 Mouse Brain Hagemann05 93genes GeneSigDB 8.834E-7 3.569E-4 2.348E-3 3.569E-4 3 83
2 12446012-Table3 Mouse Immune Carmody02 40genes GeneSigDB 2.949E-5 5.956E-3 3.919E-2 1.191E-2 2 33
3 M1349 Genes down-regulated in the urogenital sinus (UGS) of day E16 females exposed to the androgen dihydrotestosterone [PubChem=10635] for 12 h. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.888E-5 9.035E-3
5.945E-2
 3.591E-2 2 57
4 19305503-TableS1 Rat Brain Greco09 425genes GeneSigDB 8.946E-5 9.035E-3
5.945E-2
 3.614E-2 3 387
5 19305503-Table2 Rat Brain Greco09 84genes GeneSigDB 1.711E-4 1.383E-2
9.099E-2
6.914E-2
 2 79
6 M2580 Genes consistently down-regulated in mature mammary luminal cells both in mouse and human species. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.688E-4 1.810E-2
1.191E-1
1.086E-1
 2 99
7 M8939 Genes up-regulated in visceral adipose tissue of aged mice: T reg versus T conv. MSigDB C7: Immunologic Signatures (v6.0) 4.420E-4 2.551E-2
1.678E-1
1.786E-1
 2 127
8 M2648 Genes up-regulated in MCF-7 cells (breast cancer) over-expressing a mutant K112E form of CCND1 [Gene ID=595] gene. MSigDB C6: Oncogenic Signatures (v6.0) 9.744E-4 2.752E-2
1.811E-1
3.937E-1
 2 189
9 M2686 Genes up-regulated in myometrial cells over-expressing ATF2 [Gene ID=1386] gene. MSigDB C6: Oncogenic Signatures (v6.0) 9.847E-4 2.752E-2
1.811E-1
3.978E-1
 2 190
10 M2905 Genes up-regulated in DLD1 cells (colon carcinoma) over-expressing LEF1 [Gene ID=51176]. MSigDB C6: Oncogenic Signatures (v6.0) 1.037E-3 2.752E-2
1.811E-1
4.188E-1
 2 195
11 M3295 Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 1 day after stimulation with YF17D vaccine versus PBMC 7 days after the stimulation. MSigDB C7: Immunologic Signatures (v6.0) 1.047E-3 2.752E-2
1.811E-1
4.231E-1
 2 196
12 M6547 Genes up-regulated in activated macrophages: classically (M1) versus alternative (M2). MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.752E-2
1.811E-1
4.404E-1
 2 200
13 M3096 Genes up-regulated in comparison of healthy myeloid cells versus systemic lupus erythematosus myeloid cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.752E-2
1.811E-1
4.404E-1
 2 200
14 M5713 Genes up-regulated in comparison of Ctrlrv versus Foxp3rv (see Fig. 1 in the paper for details). MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.752E-2
1.811E-1
4.404E-1
 2 200
15 M3209 Genes up-regulated in comparison of immature NK cells versus intermediate mature NK cells. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.752E-2
1.811E-1
4.404E-1
 2 200
16 M7268 Genes up-regulated in double positive thymocytes: wildtype versus TCF3 [GeneID=6929] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.090E-3 2.752E-2
1.811E-1
4.404E-1
 2 200
17 M1762 Genes up-regulated in EpiSC cells (epiblast stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.814E-3 4.072E-2
2.679E-1
7.329E-1
 1 7
18 M1761 Genes up-regulated in EpiSC cells (mouse epiblast embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.814E-3 4.072E-2
2.679E-1
7.329E-1
 1 7
19 19861896-Table3 Human Brain Castells09 10genes GeneSigDB 2.332E-3 4.958E-2
3.263E-1
9.421E-1
 1 9
Show 14 more annotations

14: Coexpression Atlas [Display Chart] 6 input genes in category / 798 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 100 k2 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.884E-5 7.760E-3
5.634E-2
 1.503E-2 2 25
2 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k1 200 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k-means-cluster#1 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 2.203E-5 7.760E-3
5.634E-2
 1.758E-2 2 27
3 gudmap developingLowerUrinaryTract P1 bladder J 500 k5 DevelopingLowerUrinaryTract P1 bladder J emap-30374 k-means-cluster#5 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.917E-5 7.760E-3
5.634E-2
 2.328E-2 2 31
4 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k2 100 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 4.407E-5 8.093E-3
5.875E-2
 3.517E-2 2 38
5 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 200 k2 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 k-means-cluster#2 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 7.362E-5 8.093E-3
5.875E-2
5.875E-2
 2 49
6 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k5 200 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#5 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 7.362E-5 8.093E-3
5.875E-2
5.875E-2
 2 49
7 BM Top 100 - thalamus BM Top 100 - thalamus Body Map 1.220E-4 8.093E-3
5.875E-2
9.740E-2
 2 63
8 BM Top 100 - substantia nigra BM Top 100 - substantia nigra Body Map 1.260E-4 8.093E-3
5.875E-2
1.005E-1
 2 64
9 BM Top 100 - medulla BM Top 100 - medulla Body Map 1.300E-4 8.093E-3
5.875E-2
1.037E-1
 2 65
10 BM Top 100 - spinal cord BM Top 100 - spinal cord Body Map 1.340E-4 8.093E-3
5.875E-2
1.069E-1
 2 66
11 BM Top 100 - ventral tegmental area BM Top 100 - ventral tegmental area Body Map 1.423E-4 8.093E-3
5.875E-2
1.135E-1
 2 68
12 BM Top 100 - vestibular nuclei superior BM Top 100 - vestibular nuclei superior Body Map 1.465E-4 8.093E-3
5.875E-2
1.169E-1
 2 69
13 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k2 500 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.551E-4 8.093E-3
5.875E-2
1.238E-1
 2 71
14 BM Top 100 - dorsal root ganglia BM Top 100 - dorsal root ganglia Body Map 1.596E-4 8.093E-3
5.875E-2
1.273E-1
 2 72
15 BM Top 100 - midbrain BM Top 100 - midbrain Body Map 1.596E-4 8.093E-3
5.875E-2
1.273E-1
 2 72
16 BM Top 100 - hypothalamus BM Top 100 - hypothalamus Body Map 1.686E-4 8.093E-3
5.875E-2
1.345E-1
 2 74
17 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 100 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 100 Gudmap Mouse ST 1.0 1.732E-4 8.093E-3
5.875E-2
1.382E-1
 2 75
18 BM Top 100 - trigeminal ganglia BM Top 100 - trigeminal ganglia Body Map 1.825E-4 8.093E-3
5.875E-2
1.457E-1
 2 77
19 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 100 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 2.439E-4 9.635E-3
6.995E-2
1.947E-1
 2 89
20 gudmap developingLowerUrinaryTract P1 bladder J 1000 k4 DevelopingLowerUrinaryTract P1 bladder J emap-30374 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 2.495E-4 9.635E-3
6.995E-2
1.991E-1
 2 90
21 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 100 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 2.550E-4 9.635E-3
6.995E-2
2.035E-1
 2 91
22 gudmap developingLowerUrinaryTract e14.5 urogenital sinus 500 k1 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-5517 k-means-cluster#1 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.838E-4 9.635E-3
6.995E-2
2.265E-1
 2 96
23 gudmap dev lower uro neuro e14.5 PelvicGanglion Sox10 100 dev lower uro neuro e14.5 PelvicGanglion Sox10 top-relative-expression-ranked 100 Gudmap Mouse ST 1.0 2.898E-4 9.635E-3
6.995E-2
2.312E-1
 2 97
24 gudmap dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 100 dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 100 Gudmap Mouse ST 1.0 2.898E-4 9.635E-3
6.995E-2
2.312E-1
 2 97
25 facebase RNAseq e10.5 Emin LatNas 2500 K2 facebase RNAseq e10.5 Emin LatNas 2500 K2 Gudmap RNAseq 3.330E-4 1.063E-2
7.718E-2
2.658E-1
 2 104
26 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 500 k2 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 3.525E-4 1.082E-2
7.855E-2
2.813E-1
 2 107
27 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 1000 k1 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.930E-4 1.162E-2
8.434E-2
3.137E-1
 2 113
28 Arv EB-LF 1000 K1 AravindRamakr EmbryoidBody-LF top-relative-expression-ranked 1000 k-means-cluster#1 PCBC 4.431E-4 1.263E-2
9.168E-2
3.536E-1
 2 120
29 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k2 500 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.961E-4 1.365E-2
9.911E-2
3.959E-1
 2 127
30 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 1000 k3 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.603E-4 1.490E-2
1.082E-1
4.471E-1
 2 135
31 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k2 1000 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 k-means-cluster#2 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.854E-4 1.507E-2
1.094E-1
4.671E-1
 2 138
32 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 200 dev lower uro neuro e15.5 PelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 6.728E-4 1.678E-2
1.218E-1
5.369E-1
 2 148
33 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 200 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 8.553E-4 2.020E-2
1.467E-1
6.825E-1
 2 167
34 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 200 DevelopingLowerUrinaryTract e14.5 urethra emap-30902 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 8.860E-4 2.020E-2
1.467E-1
7.071E-1
 2 170
35 gudmap dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 200 dev lower uro neuro e15.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 8.860E-4 2.020E-2
1.467E-1
7.071E-1
 2 170
36 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hRgl Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 9.707E-4 2.094E-2
1.520E-1
7.746E-1
 2 178
37 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 200 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 9.707E-4 2.094E-2
1.520E-1
7.746E-1
 2 178
38 Glioblastoma Single Cell Merged Neoplastic Overall Top 200 Genes Glioblastoma Single Cell Merged Neoplastic Overall Top 200 Genes 1.048E-3 2.201E-2
1.598E-1
8.362E-1
 2 185
39 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC1/Kidney Tumour VHL RCC MNP RCC1 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney MNP RCC1/Kidney Tumour VHL RCC MNP RCC1 Adult, Development, and Cancer types 1.128E-3 2.232E-2
1.621E-1
9.001E-1
 2 192
40 gudmap dev lower uro neuro e14.5 PelvicGanglion Sox10 200 dev lower uro neuro e14.5 PelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.151E-3 2.232E-2
1.621E-1
9.188E-1
 2 194
41 gudmap dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 200 dev lower uro neuro e14.5 BladdPelvicGanglion Sox10 top-relative-expression-ranked 200 Gudmap Mouse ST 1.0 1.151E-3 2.232E-2
1.621E-1
9.188E-1
 2 194
42 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour VHL RCC U U/Kidney Tumour VHL RCC U8 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U U/Kidney Tumour VHL RCC U U/Kidney Tumour VHL RCC U8 Adult, Development, and Cancer types 1.175E-3 2.232E-2
1.621E-1
9.376E-1
 2 196
43 gudmap developingLowerUrinaryTract e14.5 urogenital sinus 1000 k3 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-5517 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.309E-3 2.429E-2
1.764E-1
1.000E0
 2 207
44 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k1 1000 DevelopingLowerUrinaryTract e14.5 urogenital sinus emap-6689 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.437E-3 2.607E-2
1.892E-1
1.000E0
 2 217
45 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 SubstantiaNigra Top 200 Genes BrainMap 1.544E-3 2.738E-2
1.988E-1
1.000E0
 2 225
46 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-F Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-F Lungmap CCHMC 1.768E-3 3.052E-2
2.216E-1
1.000E0
 2 241
47 Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-A Lungmap Mouse Lung PND1 MyoFB Subtype MyoFB-A Lungmap CCHMC 1.797E-3 3.052E-2
2.216E-1
1.000E0
 2 243
48 BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Cerebellum/Cerebellum/Astrocyte BrainMap/BrainAtlas - Mouse McCarroll/Tissue and Type by Type - Tissue vs Type (clevel sub)/Cerebellum/Cerebellum/Astrocyte BrainMap 2.197E-3 3.653E-2
2.652E-1
1.000E0
 1 8
49 StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells immature neurons immature neurons Subtype immature neurons s1 Top 200 Genes StanfordMouse+HumanSingleCells StanfordMouse+HumanSingleCells immature neurons immature neurons Subtype immature neurons s1 Top 200 Genes StanfordMouse+HumanSingleCells 2.278E-3 3.709E-2
2.693E-1
1.000E0
 2 274
50 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup4 Inhibitory.subGroup4 Subtype Inhibitory.subGroup4 SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup4 Inhibitory.subGroup4 Subtype Inhibitory.subGroup4 SubstantiaNigra Top 200 Genes BrainMap 2.410E-3 3.847E-2
2.793E-1
1.000E0
 2 282
Show 45 more annotations

15: Computational [Display Chart] 4 input genes in category / 26 annotations before applied cutoff / 10037 genes in category

No results to display

16: MicroRNA [Display Chart] 6 input genes in category / 98 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-210:mirSVR highEffct hsa-miR-210:mirSVR conserved highEffect-0.5 MicroRNA.org 1.069E-4 1.047E-2
5.411E-2
 1.047E-2 2 194
2 hsa-miR-210:PITA hsa-miR-210:PITA TOP PITA 2.655E-3 2.542E-2
1.313E-1
2.602E-1
 1 32
3 hsa-miR-210-3p:TargetScan hsa-miR-210-3p TargetScan 2.655E-3 2.542E-2
1.313E-1
2.602E-1
 1 32
4 hsa-miR-487b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.318E-3 2.542E-2
1.313E-1
3.251E-1
 1 40
5 hsa-miR-425-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.980E-3 2.542E-2
1.313E-1
3.901E-1
 1 48
6 hsa-miR-7705:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.311E-3 2.542E-2
1.313E-1
4.225E-1
 1 52
7 hsa-miR-4777-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.560E-3 2.542E-2
1.313E-1
4.468E-1
 1 55
8 hsa-miR-523-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
9 hsa-miR-519b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
10 hsa-miR-526a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
11 hsa-miR-518e-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
12 hsa-miR-518d-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
13 hsa-miR-519c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
14 hsa-miR-519a-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
15 hsa-miR-518f-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
16 hsa-miR-520c-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.542E-2
1.313E-1
4.955E-1
 1 61
17 hsa-miR-190b:Functional MTI Functional MTI miRTarbase 5.139E-3 2.542E-2
1.313E-1
5.036E-1
 1 62
18 hsa-miR-522-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.139E-3 2.542E-2
1.313E-1
5.036E-1
 1 62
19 hsa-miR-3679-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.542E-2
1.313E-1
5.117E-1
 1 63
20 hsa-miR-190a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 5.304E-3 2.542E-2
1.313E-1
5.198E-1
 1 64
21 hsa-miR-4699-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.552E-3 2.542E-2
1.313E-1
5.441E-1
 1 67
22 hsa-miR-1185-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.800E-3 2.542E-2
1.313E-1
5.684E-1
 1 70
23 hsa-miR-1225-3p:PITA hsa-miR-1225-3p:PITA TOP PITA 5.965E-3 2.542E-2
1.313E-1
5.846E-1
 1 72
24 hsa-miR-1245b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.544E-3 2.672E-2
1.381E-1
6.413E-1
 1 79
25 hsa-miR-193a-5p:PITA hsa-miR-193a-5p:PITA TOP PITA 7.700E-3 2.825E-2
1.460E-1
7.546E-1
 1 93
26 hsa-miR-432-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.782E-3 2.825E-2
1.460E-1
7.626E-1
 1 94
27 hsa-miR-5683:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.277E-3 2.825E-2
1.460E-1
8.112E-1
 1 100
28 hsa-miR-1255a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.442E-3 2.825E-2
1.460E-1
8.273E-1
 1 102
29 hsa-miR-1255b-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.442E-3 2.825E-2
1.460E-1
8.273E-1
 1 102
30 AGGAAGC,MIR-516-3P:MSigDB AGGAAGC,MIR-516-3P:MSigDB MSigDB 8.772E-3 2.825E-2
1.460E-1
8.596E-1
 1 106
31 hsa-miR-3605-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.937E-3 2.825E-2
1.460E-1
8.758E-1
 1 108
32 hsa-miR-589:PITA hsa-miR-589:PITA TOP PITA 9.761E-3 2.948E-2
1.523E-1
9.566E-1
 1 118
33 hsa-miR-1182:PITA hsa-miR-1182:PITA TOP PITA 9.926E-3 2.948E-2
1.523E-1
9.727E-1
 1 120
34 hsa-miR-2392:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.157E-2 3.245E-2
1.677E-1
1.000E0
 1 140
35 hsa-miR-1231:PITA hsa-miR-1231:PITA TOP PITA 1.248E-2 3.245E-2
1.677E-1
1.000E0
 1 151
36 hsa-miR-766:PITA hsa-miR-766:PITA TOP PITA 1.272E-2 3.245E-2
1.677E-1
1.000E0
 1 154
37 hsa-miR-502-3p:PITA hsa-miR-502-3p:PITA TOP PITA 1.395E-2 3.245E-2
1.677E-1
1.000E0
 1 169
38 hsa-miR-501-3p:PITA hsa-miR-501-3p:PITA TOP PITA 1.404E-2 3.245E-2
1.677E-1
1.000E0
 1 170
39 hsa-miR-1294:PITA hsa-miR-1294:PITA TOP PITA 1.445E-2 3.245E-2
1.677E-1
1.000E0
 1 175
40 hsa-miR-193a-5p:TargetScan hsa-miR-193a-5p TargetScan 1.453E-2 3.245E-2
1.677E-1
1.000E0
 1 176
41 hsa-miR-6083:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.469E-2 3.245E-2
1.677E-1
1.000E0
 1 178
42 hsa-miR-758-3p:TargetScan hsa-miR-758-3p TargetScan 1.502E-2 3.245E-2
1.677E-1
1.000E0
 1 182
43 hsa-miR-1278:PITA hsa-miR-1278:PITA TOP PITA 1.519E-2 3.245E-2
1.677E-1
1.000E0
 1 184
44 hsa-miR-297:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.568E-2 3.245E-2
1.677E-1
1.000E0
 1 190
45 AAAGACA,MIR-511:MSigDB AAAGACA,MIR-511:MSigDB MSigDB 1.568E-2 3.245E-2
1.677E-1
1.000E0
 1 190
46 hsa-miR-567:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.576E-2 3.245E-2
1.677E-1
1.000E0
 1 191
47 hsa-miR-516b:PITA hsa-miR-516b:PITA TOP PITA 1.592E-2 3.245E-2
1.677E-1
1.000E0
 1 193
48 hsa-miR-425:PITA hsa-miR-425:PITA TOP PITA 1.650E-2 3.245E-2
1.677E-1
1.000E0
 1 200
49 hsa-miR-1321:PITA hsa-miR-1321:PITA TOP PITA 1.658E-2 3.245E-2
1.677E-1
1.000E0
 1 201
50 hsa-miR-658:mirSVR highEffct hsa-miR-658:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.674E-2 3.245E-2
1.677E-1
1.000E0
 1 203
Show 45 more annotations

17: Drug [Display Chart] 6 input genes in category / 2280 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID005195771 1-phenylpentan-3-amine Stitch 3.671E-8 5.679E-5 4.719E-4 8.369E-5 3 29
2 CID000445780 AC1L9IK6 Stitch 4.981E-8 5.679E-5 4.719E-4 1.136E-4 3 32
3 CID000100657 diphenyl ditelluride Stitch 8.622E-7 5.624E-4 4.674E-3 1.966E-3 2 6
4 CID000023715 D90A Stitch 9.867E-7 5.624E-4 4.674E-3 2.250E-3 3 85
5 ctd:C056723 FG 9041 CTD 1.609E-6 7.337E-4 6.097E-3 3.669E-3 2 8
6 ctd:D018691 Excitatory Amino Acid Antagonists CTD 2.069E-6 7.860E-4 6.531E-3 4.716E-3 2 9
7 CID000013296 4-ethylsulfonylnaphthalene-1-sulfonamide Stitch 3.012E-6 8.080E-4 6.714E-3 6.867E-3 3 123
8 CID000114812 nASCs Stitch 3.159E-6 8.080E-4 6.714E-3 7.204E-3 2 11
9 ctd:C434247 diphenylditelluride CTD 3.791E-6 8.080E-4 6.714E-3 8.643E-3 2 12
10 CID000018995 Exiproben Stitch 3.791E-6 8.080E-4 6.714E-3 8.643E-3 2 12
11 ctd:C010063 carbonyl sulfide CTD 3.898E-6 8.080E-4 6.714E-3 8.888E-3 3 134
12 CID000446537 C-cluster Stitch 4.352E-6 8.270E-4 6.871E-3 9.923E-3 3 139
13 CID005326475 AC1NS0KV Stitch 4.942E-6 8.668E-4 7.202E-3 1.127E-2 3 145
14 ctd:C012587 3,5,6-trichloro-2-pyridinol CTD 6.029E-6 9.819E-4 8.159E-3 1.375E-2 2 15
15 ctd:D018750 6-Cyano-7-nitroquinoxaline-2,3-dione CTD 6.889E-6 1.047E-3 8.701E-3 1.571E-2 2 16
16 CID000003815 K252c Stitch 8.782E-6 1.251E-3 1.040E-2 2.002E-2 2 18
17 CID000092422 AC1L3O3D Stitch 1.090E-5 1.314E-3 1.092E-2 2.486E-2 2 20
18 CID000008149 IDPN Stitch 1.090E-5 1.314E-3 1.092E-2 2.486E-2 2 20
19 CID000001070 11-cis-retinal Stitch 1.095E-5 1.314E-3 1.092E-2 2.497E-2 3 189
20 CID000179536 CPD-7022 Stitch 1.205E-5 1.374E-3 1.141E-2 2.747E-2 2 21
21 6164 UP aspirin, USP; Up 200; 100uM; HL60; HT HG-U133A Broad Institute CMAP Up 1.278E-5 1.387E-3 1.153E-2 2.914E-2 3 199
22 CID000448615 AC1L9M5J Stitch 1.749E-5 1.813E-3 1.506E-2 3.988E-2 3 221
23 CID000071372 iron (II) d-gluconate dihydrate Stitch 1.864E-5 1.847E-3 1.535E-2 4.249E-2 2 26
24 CID000001032 propionate Stitch 2.909E-5 2.759E-3 2.293E-2
6.632E-2
 3 262
25 CID003330140 Px A Stitch 3.025E-5 2.759E-3 2.293E-2
6.898E-2
 2 33
26 CID000001253 (+/-)-Huperzine A Stitch 3.608E-5 3.106E-3 2.581E-2
8.227E-2
 2 36
27 CID000445227 N-Fg Stitch 3.814E-5 3.106E-3 2.581E-2
8.696E-2
 2 37
28 CID006442852 AC1O5Y0F Stitch 3.814E-5 3.106E-3 2.581E-2
8.696E-2
 2 37
29 ctd:C104223 aluminum lactate CTD 4.026E-5 3.165E-3 2.630E-2
9.179E-2
 2 38
30 ctd:D003620 Dantrolene CTD 4.694E-5 3.511E-3 2.918E-2
1.070E-1
 2 41
31 CID000001345 PK11195 Stitch 4.928E-5 3.511E-3 2.918E-2
1.124E-1
 2 42
32 ctd:C091888 monoisoamyl-2,3-dimercaptosuccinate CTD 4.928E-5 3.511E-3 2.918E-2
1.124E-1
 2 42
33 CID000620368 A805480 Stitch 5.413E-5 3.740E-3 3.108E-2
1.234E-1
 2 44
34 CID000449245 1yej Stitch 5.665E-5 3.799E-3 3.156E-2
1.292E-1
 2 45
35 ctd:C072105 KN 93 CTD 5.921E-5 3.857E-3 3.205E-2
1.350E-1
 2 46
36 CID005318463 iridal Stitch 6.452E-5 4.086E-3 3.395E-2
1.471E-1
 2 48
37 CID000021162 Trimethyltin ion Stitch 7.005E-5 4.317E-3 3.587E-2
1.597E-1
 2 50
38 CID000003512 NSC34533 Stitch 8.179E-5 4.748E-3 3.945E-2
1.865E-1
 2 54
39 CID000208924 AC1L4LMA Stitch 8.179E-5 4.748E-3 3.945E-2
1.865E-1
 2 54
40 CID000104806 peroxynitrite Stitch 8.330E-5 4.748E-3 3.945E-2
1.899E-1
 3 373
41 CID000008035 2,5-hexanedione Stitch 8.800E-5 4.894E-3 4.066E-2
2.006E-1
 2 56
42 ctd:D010400 Penicillin G CTD 9.119E-5 4.950E-3 4.113E-2
2.079E-1
 2 57
43 CID000158389 brass Stitch 9.444E-5 5.007E-3 4.161E-2
2.153E-1
 2 58
44 CID000007905 CH3Hg Stitch 1.011E-4 5.011E-3 4.164E-2
2.305E-1
 2 60
45 CID000045285 dioxamate Stitch 1.011E-4 5.011E-3 4.164E-2
2.305E-1
 2 60
46 ctd:C060229 1-(6-((3-methoxyestra-1,3,5(10)-trien-17-yl)amino)hexyl)-1H-pyrrole-2,5-dione CTD 1.011E-4 5.011E-3 4.164E-2
2.305E-1
 2 60
47 CID000448772 32 P Stitch 1.064E-4 5.129E-3 4.262E-2
2.425E-1
 3 405
48 ctd:D004533 Egtazic Acid CTD 1.080E-4 5.129E-3 4.262E-2
2.462E-1
 2 62
49 CID006338557 O-EC Stitch 1.625E-4 7.560E-3
6.282E-2
3.705E-1
 2 76
50 ctd:D002330 Carmustine CTD 1.814E-4 8.094E-3
6.725E-2
4.137E-1
 3 485
Show 45 more annotations

18: Disease [Display Chart] 6 input genes in category / 295 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C1850386 GIANT AXONAL NEUROPATHY 1 DisGeNET Curated 2.397E-6 7.072E-4 4.431E-3 7.072E-4 2 7
2 C0280793 Mixed Oligodendroglioma-Astrocytoma DisGeNET Curated 2.630E-5 2.832E-3 1.775E-2 7.760E-3 2 22
3 C0265101 Carotid artery occlusion DisGeNET BeFree 2.881E-5 2.832E-3 1.775E-2 8.497E-3 2 23
4 C1862939 AMYOTROPHIC LATERAL SCLEROSIS 1 DisGeNET Curated 2.425E-4 1.431E-2
8.965E-2
7.154E-2
 2 66
5 C0339525 Autosomal dominant retinitis pigmentosa DisGeNET BeFree 2.425E-4 1.431E-2
8.965E-2
7.154E-2
 2 66
6 cv:C0270726 Alexander's disease Clinical Variations 3.703E-4 1.815E-2
1.138E-1
1.092E-1
 1 1
7 C4024896 Motor neuron atrophy DisGeNET BeFree 4.610E-4 1.815E-2
1.138E-1
1.360E-1
 2 91
8 C2985171 Glioneuronal Tumor with Neuropil-Like Islands DisGeNET BeFree 7.404E-4 1.815E-2
1.138E-1
2.184E-1
 1 2
9 C4024930 Diffuse demyelination of the cerebral white matter DisGeNET Curated 7.404E-4 1.815E-2
1.138E-1
2.184E-1
 1 2
10 C0037917 Spina Bifida Cystica DisGeNET Curated 7.404E-4 1.815E-2
1.138E-1
2.184E-1
 1 2
11 C0796068 Oculodigitoesophagoduodenal syndrome DisGeNET Curated 7.404E-4 1.815E-2
1.138E-1
2.184E-1
 1 2
12 C0085084 Motor Neuron Disease DisGeNET Curated 7.607E-4 1.815E-2
1.138E-1
2.244E-1
 2 117
13 C0027809 Neurilemmoma DisGeNET Curated 8.000E-4 1.815E-2
1.138E-1
2.360E-1
 2 120
14 C0014038 Encephalitis DisGeNET Curated 9.814E-4 1.820E-2
1.140E-1
2.895E-1
 2 133
15 C1320640 Peripheral degeneration of retina DisGeNET BeFree 1.110E-3 1.820E-2
1.140E-1
3.276E-1
 1 3
16 C4024762 Pattern dystrophy of the retina DisGeNET BeFree 1.110E-3 1.820E-2
1.140E-1
3.276E-1
 1 3
17 C2751290 CHOROIDAL DYSTROPHY, CENTRAL AREOLAR 2 DisGeNET Curated 1.110E-3 1.820E-2
1.140E-1
3.276E-1
 1 3
18 C0596298 Cerebrovascular Occlusion DisGeNET BeFree 1.110E-3 1.820E-2
1.140E-1
3.276E-1
 1 3
19 cv:C1862939 Amyotrophic lateral sclerosis type 1 Clinical Variations 1.480E-3 1.840E-2
1.153E-1
4.367E-1
 1 4
20 C1395088 Nervous system--Degeneration DisGeNET BeFree 1.480E-3 1.840E-2
1.153E-1
4.367E-1
 1 4
21 C0339513 Dominant drusen DisGeNET BeFree 1.480E-3 1.840E-2
1.153E-1
4.367E-1
 1 4
22 C1856507 Bulbar signs DisGeNET Curated 1.480E-3 1.840E-2
1.153E-1
4.367E-1
 1 4
23 C1334363 Large Cell Lung Neuroendocrine Carcinoma DisGeNET BeFree 1.480E-3 1.840E-2
1.153E-1
4.367E-1
 1 4
24 C0751396 Well Differentiated Oligodendroglioma DisGeNET BeFree 1.505E-3 1.840E-2
1.153E-1
4.439E-1
 2 165
25 C0028945 oligodendroglioma DisGeNET Curated 1.559E-3 1.840E-2
1.153E-1
4.600E-1
 2 168
26 C0020255 Hydrocephalus DisGeNET Curated 1.729E-3 1.882E-2
1.179E-1
5.100E-1
 2 177
27 OMIN:105400 AMYOTROPHIC LATERAL SCLEROSIS 1; ALS1 OMIM 1.850E-3 1.882E-2
1.179E-1
5.458E-1
 1 5
28 C0878520 beta Thalassemia, heterozygous DisGeNET BeFree 1.850E-3 1.882E-2
1.179E-1
5.458E-1
 1 5
29 C0278878 adult glioblastoma DisGeNET BeFree 1.850E-3 1.882E-2
1.179E-1
5.458E-1
 1 5
30 C0547065 Mixed oligoastrocytoma DisGeNET BeFree 2.220E-3 1.984E-2
1.243E-1
6.548E-1
 1 6
31 C3887662 Intraspinal Neoplasm DisGeNET BeFree 2.220E-3 1.984E-2
1.243E-1
6.548E-1
 1 6
32 C1842475 Retinitis Pigmentosa 7 DisGeNET Curated 2.220E-3 1.984E-2
1.243E-1
6.548E-1
 1 6
33 C0037939 Spinal Neoplasms DisGeNET BeFree 2.220E-3 1.984E-2
1.243E-1
6.548E-1
 1 6
34 C1833030 PALMOPLANTAR KERATODERMA, NONEPIDERMOLYTIC DisGeNET Curated 2.589E-3 2.182E-2
1.368E-1
7.639E-1
 1 7
35 C0038874 Supratentorial Neoplasms DisGeNET Curated 2.589E-3 2.182E-2
1.368E-1
7.639E-1
 1 7
36 C0233794 Memory impairment DisGeNET Curated 2.799E-3 2.238E-2
1.402E-1
8.258E-1
 2 226
37 C1536451 Central areolar choroidal sclerosis DisGeNET Curated 2.959E-3 2.238E-2
1.402E-1
8.729E-1
 1 8
38 C1335392 Pericytic Neoplasm DisGeNET BeFree 2.959E-3 2.238E-2
1.402E-1
8.729E-1
 1 8
39 C1842914 Adult-Onset Vitelliform Macular Dystrophy DisGeNET Curated 2.959E-3 2.238E-2
1.402E-1
8.729E-1
 1 8
40 C0158944 Infections specific to perinatal period DisGeNET BeFree 3.328E-3 2.338E-2
1.465E-1
9.818E-1
 1 9
41 C0085315 Toxoplasmosis, Cerebral DisGeNET BeFree 3.328E-3 2.338E-2
1.465E-1
9.818E-1
 1 9
42 C0334582 Fibrillary Astrocytoma DisGeNET Curated 3.328E-3 2.338E-2
1.465E-1
9.818E-1
 1 9
43 C0026838 Muscle Spasticity DisGeNET Curated 3.440E-3 2.360E-2
1.479E-1
1.000E0
 2 251
44 C0349217 Depressive episode, unspecified DisGeNET Curated 3.697E-3 2.424E-2
1.519E-1
1.000E0
 1 10
45 C0022584 Keratoderma, Palmoplantar, Diffuse DisGeNET Curated 3.697E-3 2.424E-2
1.519E-1
1.000E0
 1 10
46 C0032019 Pituitary Neoplasms DisGeNET Curated 3.941E-3 2.444E-2
1.531E-1
1.000E0
 2 269
47 C0206042 Fatal Familial Insomnia DisGeNET Curated 4.067E-3 2.444E-2
1.531E-1
1.000E0
 1 11
48 C0264936 Secondary pulmonary hypertension DisGeNET BeFree 4.067E-3 2.444E-2
1.531E-1
1.000E0
 1 11
49 C1832370 MYOPATHY, MYOFIBRILLAR, DESMIN-RELATED DisGeNET Curated 4.067E-3 2.444E-2
1.531E-1
1.000E0
 1 11
50 C0002793 Anaplasia DisGeNET Curated 4.233E-3 2.444E-2
1.531E-1
1.000E0
 2 279
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