Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc448_6, positive side

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1: GO: Molecular Function [Display Chart] 6 input genes in category / 35 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0003887 DNA-directed DNA polymerase activity 3.245E-5 1.136E-3 4.709E-3 1.136E-3 2 28
2 GO:0034061 DNA polymerase activity 9.253E-5 1.619E-3 6.715E-3 3.239E-3 2 47
3 GO:0051082 unfolded protein binding 4.461E-4 5.118E-3 2.122E-2 1.561E-2 2 103
4 GO:0030337 DNA polymerase processivity factor activity 6.430E-4 5.118E-3 2.122E-2 2.250E-2 1 2
5 GO:0016779 nucleotidyltransferase activity 7.312E-4 5.118E-3 2.122E-2 2.559E-2 2 132
6 GO:0032139 dinucleotide insertion or deletion binding 9.643E-4 5.625E-3 2.333E-2 3.375E-2 1 3
7 GO:0032135 DNA insertion or deletion binding 1.928E-3 7.497E-3 3.109E-2
6.748E-2
 1 6
8 GO:0070087 chromo shadow domain binding 1.928E-3 7.497E-3 3.109E-2
6.748E-2
 1 6
9 GO:0032405 MutLalpha complex binding 1.928E-3 7.497E-3 3.109E-2
6.748E-2
 1 6
10 GO:0032404 mismatch repair complex binding 2.570E-3 8.994E-3 3.730E-2
8.994E-2
 1 8
11 GO:0000701 purine-specific mismatch base pair DNA N-glycosylase activity 3.853E-3 1.043E-2 4.326E-2
1.348E-1
 1 12
12 GO:0030983 mismatched DNA binding 3.853E-3 1.043E-2 4.326E-2
1.348E-1
 1 12
13 GO:0070182 DNA polymerase binding 4.173E-3 1.043E-2 4.326E-2
1.461E-1
 1 13
14 GO:0000700 mismatch base pair DNA N-glycosylase activity 4.173E-3 1.043E-2 4.326E-2
1.461E-1
 1 13
15 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed 5.454E-3 1.255E-2
5.203E-2
1.909E-1
 1 17
16 GO:0019104 DNA N-glycosylase activity 5.774E-3 1.255E-2
5.203E-2
2.021E-1
 1 18
17 GO:1990939 ATP-dependent microtubule motor activity 6.094E-3 1.255E-2
5.203E-2
2.133E-1
 1 19
18 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds 8.012E-3 1.558E-2
6.461E-2
2.804E-1
 1 25
19 GO:0035035 histone acetyltransferase binding 9.608E-3 1.770E-2
7.340E-2
3.363E-1
 1 30
20 GO:0030507 spectrin binding 1.025E-2 1.793E-2
7.436E-2
3.586E-1
 1 32
21 GO:0019894 kinesin binding 1.343E-2 2.238E-2
9.282E-2
4.701E-1
 1 42
22 GO:0030331 estrogen receptor binding 1.502E-2 2.389E-2
9.908E-2
5.257E-1
 1 47
23 GO:0030971 receptor tyrosine kinase binding 1.914E-2 2.913E-2
1.208E-1
6.699E-1
 1 60
24 GO:0003684 damaged DNA binding 2.072E-2 2.945E-2
1.221E-1
7.252E-1
 1 65
25 GO:1990782 protein tyrosine kinase binding 2.104E-2 2.945E-2
1.221E-1
7.363E-1
 1 66
26 GO:0003777 microtubule motor activity 2.451E-2 3.299E-2
1.368E-1
8.577E-1
 1 77
27 GO:0035258 steroid hormone receptor binding 2.828E-2 3.666E-2
1.520E-1
9.898E-1
 1 89
Show 22 more annotations

2: GO: Biological Process [Display Chart] 6 input genes in category / 214 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0006260 DNA replication 1.271E-8 2.720E-6 1.617E-5 2.720E-6 5 346
2 GO:0006297 nucleotide-excision repair, DNA gap filling 3.752E-8 3.041E-6 1.808E-5 8.028E-6 3 24
3 GO:0006271 DNA strand elongation involved in DNA replication 4.263E-8 3.041E-6 1.808E-5 9.122E-6 3 25
4 GO:0022616 DNA strand elongation 8.325E-8 3.846E-6 2.287E-5 1.781E-5 3 31
5 GO:0000722 telomere maintenance via recombination 1.108E-7 3.846E-6 2.287E-5 2.371E-5 3 34
6 GO:0006298 mismatch repair 1.212E-7 3.846E-6 2.287E-5 2.593E-5 3 35
7 GO:0042769 DNA damage response, detection of DNA damage 1.322E-7 3.846E-6 2.287E-5 2.828E-5 3 36
8 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion 1.438E-7 3.846E-6 2.287E-5 3.077E-5 3 37
9 GO:0033683 nucleotide-excision repair, DNA incision 1.691E-7 4.021E-6 2.390E-5 3.618E-5 3 39
10 GO:0019985 translesion synthesis 1.972E-7 4.220E-6 2.509E-5 4.220E-5 3 41
11 GO:0006312 mitotic recombination 2.623E-7 5.104E-6 3.035E-5 5.614E-5 3 45
12 GO:0006301 postreplication repair 4.581E-7 8.169E-6 4.857E-5 9.803E-5 3 54
13 GO:0006283 transcription-coupled nucleotide-excision repair 1.146E-6 1.887E-5 1.122E-4 2.452E-4 3 73
14 GO:0000731 DNA synthesis involved in DNA repair 1.244E-6 1.901E-5 1.130E-4 2.662E-4 3 75
15 GO:0006289 nucleotide-excision repair 5.017E-6 7.158E-5 4.256E-4 1.074E-3 3 119
16 GO:0006261 DNA-dependent DNA replication 7.171E-6 9.591E-5 5.703E-4 1.535E-3 3 134
17 GO:0000723 telomere maintenance 8.180E-6 1.030E-4 6.122E-4 1.751E-3 3 140
18 GO:0032200 telomere organization 1.068E-5 1.270E-4 7.549E-4 2.286E-3 3 153
19 GO:0071897 DNA biosynthetic process 2.797E-5 3.150E-4 1.873E-3 5.985E-3 3 211
20 GO:0006335 DNA replication-dependent nucleosome assembly 4.272E-5 4.354E-4 2.588E-3 9.143E-3 2 32
21 GO:0034723 DNA replication-dependent nucleosome organization 4.272E-5 4.354E-4 2.588E-3 9.143E-3 2 32
22 GO:0006310 DNA recombination 5.645E-5 5.491E-4 3.265E-3 1.208E-2 3 267
23 GO:0090305 nucleic acid phosphodiester bond hydrolysis 5.966E-5 5.551E-4 3.300E-3 1.277E-2 3 272
24 GO:0060249 anatomical structure homeostasis 1.902E-4 1.696E-3 1.009E-2 4.071E-2 3 402
25 GO:0099640 axo-dendritic protein transport 3.222E-4 2.377E-3 1.414E-2
6.895E-2
 1 1
26 GO:2000769 regulation of establishment or maintenance of cell polarity regulating cell shape 3.222E-4 2.377E-3 1.414E-2
6.895E-2
 1 1
27 GO:1905128 positive regulation of axo-dendritic protein transport 3.222E-4 2.377E-3 1.414E-2
6.895E-2
 1 1
28 GO:1905126 regulation of axo-dendritic protein transport 3.222E-4 2.377E-3 1.414E-2
6.895E-2
 1 1
29 GO:2000771 positive regulation of establishment or maintenance of cell polarity regulating cell shape 3.222E-4 2.377E-3 1.414E-2
6.895E-2
 1 1
30 GO:0036334 epidermal stem cell homeostasis 6.443E-4 4.309E-3 2.562E-2
1.379E-1
 1 2
31 GO:0071963 establishment or maintenance of cell polarity regulating cell shape 6.443E-4 4.309E-3 2.562E-2
1.379E-1
 1 2
32 GO:0006272 leading strand elongation 6.443E-4 4.309E-3 2.562E-2
1.379E-1
 1 2
33 GO:0006334 nucleosome assembly 8.727E-4 5.659E-3 3.365E-2
1.868E-1
 2 144
34 GO:1902990 mitotic telomere maintenance via semi-conservative replication 9.663E-4 6.082E-3 3.616E-2
2.068E-1
 1 3
35 GO:0031497 chromatin assembly 1.103E-3 6.741E-3 4.008E-2
2.359E-1
 2 162
36 GO:0034728 nucleosome organization 1.227E-3 7.295E-3 4.337E-2
2.626E-1
 2 171
37 GO:0032077 positive regulation of deoxyribonuclease activity 1.288E-3 7.451E-3 4.430E-2
2.757E-1
 1 4
38 GO:0006333 chromatin assembly or disassembly 1.481E-3 8.338E-3 4.957E-2
3.168E-1
 2 188
39 GO:0006323 DNA packaging 1.774E-3 9.733E-3
5.787E-2
3.796E-1
 2 206
40 GO:0006287 base-excision repair, gap-filling 1.932E-3 1.008E-2
5.995E-2
4.134E-1
 1 6
41 GO:0032201 telomere maintenance via semi-conservative replication 1.932E-3 1.008E-2
5.995E-2
4.134E-1
 1 6
42 GO:0065004 protein-DNA complex assembly 2.111E-3 1.076E-2
6.396E-2
4.518E-1
 2 225
43 GO:0072383 plus-end-directed vesicle transport along microtubule 2.253E-3 1.096E-2
6.516E-2
4.822E-1
 1 7
44 GO:0072386 plus-end-directed organelle transport along microtubule 2.253E-3 1.096E-2
6.516E-2
4.822E-1
 1 7
45 GO:0032070 regulation of deoxyribonuclease activity 2.575E-3 1.225E-2
7.281E-2
5.511E-1
 1 8
46 GO:0071824 protein-DNA complex subunit organization 2.639E-3 1.228E-2
7.300E-2
5.648E-1
 2 252
47 GO:0071103 DNA conformation change 3.361E-3 1.531E-2
9.100E-2
7.193E-1
 2 285
48 GO:0032075 positive regulation of nuclease activity 4.824E-3 2.151E-2
1.279E-1
1.000E0
 1 15
49 GO:0021542 dentate gyrus development 5.465E-3 2.387E-2
1.419E-1
1.000E0
 1 17
50 GO:0042276 error-prone translesion synthesis 6.107E-3 2.562E-2
1.523E-1
1.000E0
 1 19
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 6 input genes in category / 40 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0030894 replisome 7.764E-8 3.106E-6 1.329E-5 3.106E-6 3 31
2 GO:0043596 nuclear replication fork 1.839E-7 3.303E-6 1.413E-5 7.357E-6 3 41
3 GO:0033186 CAF-1 complex 2.477E-7 3.303E-6 1.413E-5 9.908E-6 2 3
4 GO:0043625 delta DNA polymerase complex 4.953E-7 4.953E-6 2.119E-5 1.981E-5 2 4
5 GO:0005657 replication fork 8.240E-7 6.592E-6 2.820E-5 3.296E-5 3 67
6 GO:0042575 DNA polymerase complex 7.502E-6 5.001E-5 2.140E-4 3.001E-4 2 14
7 GO:0032993 protein-DNA complex 1.705E-5 9.740E-5 4.167E-4 6.818E-4 3 183
8 GO:0043601 nuclear replisome 3.110E-5 1.555E-4 6.653E-4 1.244E-3 2 28
9 GO:0061695 transferase complex, transferring phosphorus-containing groups 4.028E-5 1.790E-4 7.659E-4 1.611E-3 3 244
10 GO:0044796 DNA polymerase processivity factor complex 3.148E-4 1.145E-3 4.897E-3 1.259E-2 1 1
11 GO:0043626 PCNA complex 3.148E-4 1.145E-3 4.897E-3 1.259E-2 1 1
12 GO:0070557 PCNA-p21 complex 6.295E-4 2.098E-3 8.977E-3 2.518E-2 1 2
13 GO:0016939 kinesin II complex 9.441E-4 2.905E-3 1.243E-2 3.776E-2 1 3
14 GO:0005663 DNA replication factor C complex 1.887E-3 5.393E-3 2.307E-2
7.550E-2
 1 6
15 GO:0097470 ribbon synapse 2.830E-3 7.547E-3 3.229E-2
1.132E-1
 1 9
16 GO:0005652 nuclear lamina 4.086E-3 9.717E-3 4.158E-2
1.634E-1
 1 13
17 GO:0000790 nuclear chromatin 4.130E-3 9.717E-3 4.158E-2
1.652E-1
 2 324
18 GO:0000785 chromatin 9.128E-3 2.006E-2
8.585E-2
3.651E-1
 2 487
19 GO:0000307 cyclin-dependent protein kinase holoenzyme complex 1.003E-2 2.006E-2
8.585E-2
4.013E-1
 1 32
20 GO:0030990 intraciliary transport particle 1.003E-2 2.006E-2
8.585E-2
4.013E-1
 1 32
21 GO:1904115 axon cytoplasm 1.128E-2 2.149E-2
9.193E-2
4.512E-1
 1 36
22 GO:0032391 photoreceptor connecting cilium 1.253E-2 2.278E-2
9.745E-2
5.011E-1
 1 40
23 GO:0097542 ciliary tip 1.408E-2 2.449E-2
1.048E-1
5.633E-1
 1 45
24 GO:0005871 kinesin complex 1.719E-2 2.865E-2
1.226E-1
6.876E-1
 1 55
25 GO:0005876 spindle microtubule 1.874E-2 2.999E-2
1.283E-1
7.496E-1
 1 60
26 GO:0032838 plasma membrane bounded cell projection cytoplasm 1.967E-2 3.026E-2
1.295E-1
7.868E-1
 1 63
27 GO:1902554 serine/threonine protein kinase complex 2.523E-2 3.738E-2
1.599E-1
1.000E0
 1 81
28 GO:1902911 protein kinase complex 2.862E-2 4.088E-2
1.749E-1
1.000E0
 1 92
29 GO:0097014 ciliary plasm 3.077E-2 4.102E-2
1.755E-1
1.000E0
 1 99
30 GO:0005930 axoneme 3.077E-2 4.102E-2
1.755E-1
1.000E0
 1 99
Show 25 more annotations

4: Human Phenotype [Display Chart] 1 input genes in category / 16 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0000524 Conjunctival telangiectasia 4.886E-3 4.249E-2
1.436E-1
7.818E-2
 1 23
2 HP:0008054 Abnormal vasculature of the conjunctiva morphology 5.311E-3 4.249E-2
1.436E-1
8.498E-2
 1 25
3 HP:0100579 Mucosal telangiectasiae 8.286E-3 4.419E-2
1.494E-1
1.326E-1
 1 39

5: Mouse Phenotype [Display Chart] 6 input genes in category / 212 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 6 input genes in category / 40 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF09507 CDC27 Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
2 PF15557 CAF1-p150 N Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
3 IPR029129 CAF1 p60 C InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
4 PF15512 CAF-1 p60 C Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
5 IPR029105 CAF1-p150 C2 InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
6 IPR019038 DNA polymerase subunit Cdc27 InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
7 IPR022043 CAF1A InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
8 IPR029091 CAF1-p150 N InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
9 PF00705 PCNA N Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
10 PF02747 PCNA C Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
11 PS00293 PCNA 2 PROSITE 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
12 IPR000730 Pr cel nuc antig InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
13 PS01251 PCNA 1 PROSITE 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
14 IPR022649 Pr cel nuc antig C InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
15 IPR022659 Pr cel nuc antig CS InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
16 IPR024826 DNA pol delta/II ssu InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
17 PF15539 CAF1-p150 C2 Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
18 IPR022648 Pr cel nuc antig N InterPro 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
19 PF12253 CAF1A Pfam 3.203E-4 6.742E-4 2.885E-3 1.281E-2 1 1
20 IPR007185 DNA pol alpha/epsilon bsu InterPro 9.605E-4 1.830E-3 7.828E-3 3.842E-2 1 3
21 PF04042 DNA pol E B Pfam 9.605E-4 1.830E-3 7.828E-3 3.842E-2 1 3
22 IPR001632 Gprotein B InterPro 3.199E-3 5.816E-3 2.488E-2
1.279E-1
 1 10
23 IPR019821 Kinesin motor CS InterPro 1.306E-2 1.868E-2
7.993E-2
5.224E-1
 1 41
24 IPR027640 Kinesin-like fam InterPro 1.369E-2 1.868E-2
7.993E-2
5.478E-1
 1 43
25 PF00225 Kinesin Pfam 1.401E-2 1.868E-2
7.993E-2
5.604E-1
 1 44
26 SM00129 KISc SMART 1.401E-2 1.868E-2
7.993E-2
5.604E-1
 1 44
27 3.40.850.10 - Gene3D 1.401E-2 1.868E-2
7.993E-2
5.604E-1
 1 44
28 PS00411 KINESIN MOTOR 1 PROSITE 1.401E-2 1.868E-2
7.993E-2
5.604E-1
 1 44
29 IPR001752 Kinesin motor dom InterPro 1.401E-2 1.868E-2
7.993E-2
5.604E-1
 1 44
30 PS50067 KINESIN MOTOR 2 PROSITE 1.401E-2 1.868E-2
7.993E-2
5.604E-1
 1 44
Show 25 more annotations

7: Pathway [Display Chart] 4 input genes in category / 88 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269863 Removal of the Flap Intermediate from the C-strand BioSystems: REACTOME 1.492E-9 5.530E-8 2.798E-7 1.313E-7 3 10
2 1269862 Processive synthesis on the C-strand of the telomere BioSystems: REACTOME 2.052E-9 5.530E-8 2.798E-7 1.805E-7 3 11
3 1269790 Removal of the Flap Intermediate BioSystems: REACTOME 4.525E-9 5.530E-8 2.798E-7 3.982E-7 3 14
4 1269786 Leading Strand Synthesis BioSystems: REACTOME 4.525E-9 5.530E-8 2.798E-7 3.982E-7 3 14
5 1269861 Polymerase switching on the C-strand of the telomere BioSystems: REACTOME 4.525E-9 5.530E-8 2.798E-7 3.982E-7 3 14
6 1269787 Polymerase switching BioSystems: REACTOME 4.525E-9 5.530E-8 2.798E-7 3.982E-7 3 14
7 1270412 Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) BioSystems: REACTOME 5.656E-9 5.530E-8 2.798E-7 4.977E-7 3 15
8 1270413 Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) BioSystems: REACTOME 5.656E-9 5.530E-8 2.798E-7 4.977E-7 3 15
9 1269789 Processive synthesis on the lagging strand BioSystems: REACTOME 5.656E-9 5.530E-8 2.798E-7 4.977E-7 3 15
10 1270411 Mismatch Repair BioSystems: REACTOME 6.961E-9 6.125E-8 3.100E-7 6.125E-7 3 16
11 1269788 Lagging Strand Synthesis BioSystems: REACTOME 1.417E-8 1.133E-7 5.735E-7 1.247E-6 3 20
12 1270366 PCNA-Dependent Long Patch Base Excision Repair BioSystems: REACTOME 1.653E-8 1.212E-7 6.133E-7 1.454E-6 3 21
13 83045 Mismatch repair BioSystems: KEGG 2.200E-8 1.475E-7 7.465E-7 1.936E-6 3 23
14 1270364 Resolution of AP sites via the multiple-nucleotide patch replacement pathway BioSystems: REACTOME 2.515E-8 1.475E-7 7.465E-7 2.213E-6 3 24
15 1269859 Telomere C-strand (Lagging Strand) Synthesis BioSystems: REACTOME 2.515E-8 1.475E-7 7.465E-7 2.213E-6 3 24
16 1309116 Gap-filling DNA repair synthesis and ligation in GG-NER BioSystems: REACTOME 2.857E-8 1.572E-7 7.952E-7 2.514E-6 3 25
17 PW:0000662 mismatch repair pathway Pathway Ontology 3.230E-8 1.672E-7 8.460E-7 2.842E-6 3 26
18 1270368 Recognition of DNA damage by PCNA-containing replication complex BioSystems: REACTOME 5.042E-8 2.465E-7 1.247E-6 4.437E-6 3 30
19 1269857 Extension of Telomeres BioSystems: REACTOME 5.582E-8 2.585E-7 1.308E-6 4.912E-6 3 31
20 1269784 DNA strand elongation BioSystems: REACTOME 6.159E-8 2.710E-7 1.371E-6 5.420E-6 3 32
21 83043 Base excision repair BioSystems: KEGG 6.775E-8 2.839E-7 1.437E-6 5.962E-6 3 33
22 1270374 Termination of translesion DNA synthesis BioSystems: REACTOME 7.430E-8 2.972E-7 1.504E-6 6.538E-6 3 34
23 83039 DNA replication BioSystems: KEGG 8.864E-8 3.392E-7 1.716E-6 7.801E-6 3 36
24 1270359 Resolution of Abasic Sites (AP sites) BioSystems: REACTOME 9.646E-8 3.395E-7 1.718E-6 8.488E-6 3 37
25 1270351 Base Excision Repair BioSystems: REACTOME 9.646E-8 3.395E-7 1.718E-6 8.488E-6 3 37
26 1270369 Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template BioSystems: REACTOME 1.323E-7 4.312E-7 2.182E-6 1.164E-5 3 41
27 1309115 Dual Incision in GG-NER BioSystems: REACTOME 1.323E-7 4.312E-7 2.182E-6 1.164E-5 3 41
28 83044 Nucleotide excision repair BioSystems: KEGG 2.012E-7 6.323E-7 3.199E-6 1.770E-5 3 47
29 1270367 DNA Damage Bypass BioSystems: REACTOME 2.431E-7 7.378E-7 3.733E-6 2.140E-5 3 50
30 1309120 Gap-filling DNA repair synthesis and ligation in TC-NER BioSystems: REACTOME 5.413E-7 1.588E-6 8.035E-6 4.764E-5 3 65
31 1309119 Dual incision in TC-NER BioSystems: REACTOME 5.671E-7 1.610E-6 8.146E-6 4.990E-5 3 66
32 1309102 HDR through Homologous Recombination (HRR) BioSystems: REACTOME 6.492E-7 1.785E-6 9.034E-6 5.713E-5 3 69
33 1309117 Transcription-Coupled Nucleotide Excision Repair (TC-NER) BioSystems: REACTOME 9.792E-7 2.611E-6 1.321E-5 8.617E-5 3 79
34 1269856 Telomere Maintenance BioSystems: REACTOME 1.137E-6 2.944E-6 1.490E-5 1.001E-4 3 83
35 1309112 Global Genome Nucleotide Excision Repair (GG-NER) BioSystems: REACTOME 1.223E-6 3.074E-6 1.555E-5 1.076E-4 3 85
36 1269779 Synthesis of DNA BioSystems: REACTOME 2.187E-6 5.345E-6 2.705E-5 1.924E-4 3 103
37 1269853 Chromosome Maintenance BioSystems: REACTOME 2.667E-6 6.344E-6 3.210E-5 2.347E-4 3 110
38 1269875 DNA Replication BioSystems: REACTOME 2.741E-6 6.348E-6 3.212E-5 2.412E-4 3 111
39 1309111 Nucleotide Excision Repair BioSystems: REACTOME 2.817E-6 6.355E-6 3.216E-5 2.479E-4 3 112
40 1269777 S Phase BioSystems: REACTOME 4.624E-6 1.017E-5 5.148E-5 4.069E-4 3 132
41 1309100 HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) BioSystems: REACTOME 4.839E-6 1.039E-5 5.255E-5 4.258E-4 3 134
42 1309099 Homology Directed Repair BioSystems: REACTOME 5.522E-6 1.157E-5 5.854E-5 4.859E-4 3 140
43 P00017 DNA replication PantherDB 9.277E-6 1.899E-5 9.607E-5 8.164E-4 2 16
44 1309095 DNA Double-Strand Break Repair BioSystems: REACTOME 9.732E-6 1.946E-5 9.849E-5 8.564E-4 3 169
45 373901 HTLV-I infection BioSystems: KEGG 3.385E-5 6.620E-5 3.350E-4 2.979E-3 3 256
46 83046 Homologous recombination BioSystems: KEGG 6.322E-5 1.209E-4 6.120E-4 5.564E-3 2 41
47 1270350 DNA Repair BioSystems: REACTOME 6.540E-5 1.225E-4 6.196E-4 5.755E-3 3 319
48 82946 Pyrimidine metabolism BioSystems: KEGG 4.181E-4 7.665E-4 3.879E-3 3.679E-2 2 105
49 82944 Purine metabolism BioSystems: KEGG 1.157E-3 2.078E-3 1.052E-2
1.018E-1
 2 175
50 M14863 p53 Signaling Pathway MSigDB C2 BIOCARTA (v6.0) 5.131E-3 8.854E-3 4.480E-2
4.516E-1
 1 16
Show 45 more annotations

8: Pubmed [Display Chart] 6 input genes in category / 1670 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 16000169 An in vivo analysis of the localisation and interactions of human p66 DNA polymerase delta subunit. Pubmed 2.154E-12 3.597E-9 2.877E-8 3.597E-9 3 3
2 11328591 The human homologue of fission Yeast cdc27, p66, is a component of active human DNA polymerase delta. Pubmed 8.616E-12 7.194E-9 5.754E-8 1.439E-8 3 4
3 16510448 Functional roles of p12, the fourth subunit of human DNA polymerase delta. Pubmed 7.538E-11 4.196E-8 3.356E-7 1.259E-7 3 7
4 10559261 Reconstitution of proliferating cell nuclear antigen-dependent repair of apurinic/apyrimidinic sites with purified human proteins. Pubmed 1.809E-10 7.552E-8 6.040E-7 3.021E-7 3 9
5 11473323 RPA governs endonuclease switching during processing of Okazaki fragments in eukaryotes. Pubmed 4.736E-10 1.582E-7 1.265E-6 7.910E-7 3 12
6 9111189 Which DNA polymerases are used for DNA-repair in eukaryotes? Pubmed 1.205E-9 3.355E-7 2.683E-6 2.013E-6 3 16
7 12171929 A proteomics approach to identify proliferating cell nuclear antigen (PCNA)-binding proteins in human cell lysates. Identification of the human CHL12/RFCs2-5 complex as a novel PCNA-binding protein. Pubmed 9.667E-9 1.808E-6 1.446E-5 1.614E-5 3 31
8 22148433 Phosphorylation of the p68 subunit of Pol δ acts as a molecular switch to regulate its interaction with PCNA. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
9 18818516 X-ray structure of the complex of regulatory subunits of human DNA polymerase delta. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
10 11986310 Direct interaction of proliferating cell nuclear antigen with the small subunit of DNA polymerase delta. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
11 19822659 Two fundamentally distinct PCNA interaction peptides contribute to chromatin assembly factor 1 function. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
12 18765914 Crystallization and preliminary crystallographic analysis of the complex of the second and third regulatory subunits of human Pol delta. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
13 7600578 The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
14 29382432 [Highly expressed CHAF1A and PCNA are positively associated with malignancy of cervical squamous cell carcinoma]. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
15 10648606 A CAF-1-PCNA-mediated chromatin assembly pathway triggered by sensing DNA damage. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
16 10893180 CAF-1 and the inheritance of chromatin states: at the crossroads of DNA replication and repair. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
17 10219083 Isolation and identification of the third subunit of mammalian DNA polymerase delta by PCNA-affinity chromatography of mouse FM3A cell extracts. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
18 17932049 Dynamics of human replication factors in the elongation phase of DNA replication. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
19 11595739 Mediation of proliferating cell nuclear antigen (PCNA)-dependent DNA replication through a conserved p21(Cip1)-like PCNA-binding motif present in the third subunit of human DNA polymerase delta. Pubmed 2.057E-8 1.808E-6 1.446E-5 3.435E-5 2 2
20 28934474 Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro. Pubmed 6.170E-8 4.121E-6 3.296E-5 1.030E-4 2 3
21 10852724 Evidence that DNA polymerase delta isolated by immunoaffinity chromatography exhibits high-molecular weight characteristics and is associated with the KIAA0039 protein and RPA. Pubmed 6.170E-8 4.121E-6 3.296E-5 1.030E-4 2 3
22 11593007 A tumor necrosis factor alpha- and interleukin 6-inducible protein that interacts with the small subunit of DNA polymerase delta and proliferating cell nuclear antigen. Pubmed 6.170E-8 4.121E-6 3.296E-5 1.030E-4 2 3
23 15805117 Proliferating cell nuclear antigen (PCNA) may function as a double homotrimer complex in the mammalian cell. Pubmed 6.170E-8 4.121E-6 3.296E-5 1.030E-4 2 3
24 9614144 Nucleosome assembly activity and intracellular localization of human CAF-1 changes during the cell division cycle. Pubmed 6.170E-8 4.121E-6 3.296E-5 1.030E-4 2 3
25 22232658 Interplay between mismatch repair and chromatin assembly. Pubmed 6.170E-8 4.121E-6 3.296E-5 1.030E-4 2 3
26 12403614 Reconstitution and characterization of the human DNA polymerase delta four-subunit holoenzyme. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
27 11897662 Human Asf1 and CAF-1 interact and synergize in a repair-coupled nucleosome assembly pathway. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
28 15576034 Structural and thermodynamic analysis of human PCNA with peptides derived from DNA polymerase-delta p66 subunit and flap endonuclease-1. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
29 17081972 New histone incorporation marks sites of UV repair in human cells. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
30 16934752 The p66 and p12 subunits of DNA polymerase delta are modified by ubiquitin and ubiquitin-like proteins. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
31 8858152 Nucleosome assembly by a complex of CAF-1 and acetylated histones H3/H4. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
32 12697822 The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1. Pubmed 1.234E-7 6.439E-6 5.150E-5 2.060E-4 2 4
33 19237606 Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk. Pubmed 2.043E-7 8.805E-6 7.042E-5 3.411E-4 3 84
34 12771185 BTG2 antiproliferative protein interacts with the human CCR4 complex existing in vivo in three cell-cycle-regulated forms. Pubmed 2.056E-7 8.805E-6 7.042E-5 3.434E-4 2 5
35 24695737 The ADP-ribosyltransferase PARP10/ARTD10 interacts with proliferating cell nuclear antigen (PCNA) and is required for DNA damage tolerance. Pubmed 2.056E-7 8.805E-6 7.042E-5 3.434E-4 2 5
36 17065558 Essential role of chromatin assembly factor-1-mediated rapid nucleosome assembly for DNA replication and cell division in vertebrate cells. Pubmed 2.056E-7 8.805E-6 7.042E-5 3.434E-4 2 5
37 24939902 CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis. Pubmed 2.056E-7 8.805E-6 7.042E-5 3.434E-4 2 5
38 15327775 Methyl-CpG binding protein MBD1 couples histone H3 methylation at lysine 9 by SETDB1 to DNA replication and chromatin assembly. Pubmed 2.056E-7 8.805E-6 7.042E-5 3.434E-4 2 5
39 12522211 Identification of a novel protein, PDIP38, that interacts with the p50 subunit of DNA polymerase delta and proliferating cell nuclear antigen. Pubmed 2.056E-7 8.805E-6 7.042E-5 3.434E-4 2 5
40 19845771 Dmap1 plays an essential role in the maintenance of genome integrity through the DNA repair process. Pubmed 3.084E-7 1.256E-5 1.005E-4 5.151E-4 2 6
41 16826239 The replication kinase Cdc7-Dbf4 promotes the interaction of the p150 subunit of chromatin assembly factor 1 with proliferating cell nuclear antigen. Pubmed 3.084E-7 1.256E-5 1.005E-4 5.151E-4 2 6
42 15306854 A CAF-1 dependent pool of HP1 during heterochromatin duplication. Pubmed 4.318E-7 1.717E-5 1.373E-4 7.210E-4 2 7
43 22195966 Dynamics of histone H3 deposition in vivo reveal a nucleosome gap-filling mechanism for H3.3 to maintain chromatin integrity. Pubmed 5.756E-7 2.236E-5 1.788E-4 9.613E-4 2 8
44 20227374 Three DNA polymerases, recruited by different mechanisms, carry out NER repair synthesis in human cells. Pubmed 7.400E-7 2.746E-5 2.197E-4 1.236E-3 2 9
45 16763556 Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin. Pubmed 7.400E-7 2.746E-5 2.197E-4 1.236E-3 2 9
46 21724829 Phosphorylation of H4 Ser 47 promotes HIRA-mediated nucleosome assembly. Pubmed 1.130E-6 4.104E-5 3.282E-4 1.888E-3 2 11
47 26365490 Systematic identification of factors for provirus silencing in embryonic stem cells. Pubmed 1.201E-6 4.268E-5 3.413E-4 2.006E-3 3 151
48 17452450 Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Pubmed 1.356E-6 4.719E-5 3.775E-4 2.265E-3 2 12
49 29754823 Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Pubmed 1.603E-6 5.354E-5 4.282E-4 2.677E-3 2 13
50 15882967 The mammalian heterochromatin protein 1 binds diverse nuclear proteins through a common motif that targets the chromoshadow domain. Pubmed 1.603E-6 5.354E-5 4.282E-4 2.677E-3 2 13
Show 45 more annotations

9: Interaction [Display Chart] 6 input genes in category / 590 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:POLD4 POLD4 interactions 4.754E-9 2.805E-6 1.952E-5 2.805E-6 3 12
2 int:PCNA PCNA interactions 1.106E-8 3.263E-6 2.270E-5 6.526E-6 5 320
3 int:POLD3 POLD3 interactions 1.289E-7 2.536E-5 1.764E-4 7.608E-5 3 34
4 int:POLD2 POLD2 interactions 1.817E-7 2.680E-5 1.865E-4 1.072E-4 3 38
5 int:CHAF1B CHAF1B interactions 3.053E-7 3.603E-5 2.507E-4 1.801E-4 3 45
6 int:WRN WRN interactions 5.638E-7 5.544E-5 3.858E-4 3.326E-4 3 55
7 int:TIMELESS TIMELESS interactions 1.390E-6 1.171E-4 8.150E-4 8.199E-4 3 74
8 int:SPRTN SPRTN interactions 3.352E-6 2.334E-4 1.624E-3 1.978E-3 3 99
9 int:HIST2H3C HIST2H3C interactions 3.560E-6 2.334E-4 1.624E-3 2.101E-3 3 101
10 int:POLD1 POLD1 interactions 5.546E-6 3.131E-4 2.178E-3 3.272E-3 3 117
11 int:CBX1 CBX1 interactions 5.837E-6 3.131E-4 2.178E-3 3.444E-3 3 119
12 int:SETDB1 SETDB1 interactions 1.194E-5 5.871E-4 4.085E-3 7.045E-3 3 151
13 int:HIST1H3E HIST1H3E interactions 2.897E-5 1.181E-3 8.221E-3 1.709E-2 3 203
14 int:LIG1 LIG1 interactions 3.348E-5 1.181E-3 8.221E-3 1.975E-2 2 27
15 int:REV1 REV1 interactions 3.348E-5 1.181E-3 8.221E-3 1.975E-2 2 27
16 int:HIST1H3B HIST1H3B interactions 3.348E-5 1.181E-3 8.221E-3 1.975E-2 2 27
17 int:CHAF1A CHAF1A interactions 3.487E-5 1.181E-3 8.221E-3 2.057E-2 3 216
18 int:KCTD13 KCTD13 interactions 3.604E-5 1.181E-3 8.221E-3 2.127E-2 2 28
19 int:RBBP4 RBBP4 interactions 4.428E-5 1.375E-3 9.568E-3 2.613E-2 3 234
20 int:CNOT6L CNOT6L interactions 5.031E-5 1.484E-3 1.033E-2 2.968E-2 2 33
21 int:HIST1H4F HIST1H4F interactions 7.054E-5 1.982E-3 1.379E-2 4.162E-2 2 39
22 int:MBD1 MBD1 interactions 7.804E-5 2.093E-3 1.456E-2 4.604E-2 2 41
23 int:POLH POLH interactions 8.591E-5 2.204E-3 1.533E-2
5.069E-2
 2 43
24 int:WRNIP1 WRNIP1 interactions 1.028E-4 2.527E-3 1.758E-2
6.064E-2
 2 47
25 int:DNAJC9 DNAJC9 interactions 1.072E-4 2.531E-3 1.761E-2
6.327E-2
 2 48
26 int:ASF1B ASF1B interactions 1.569E-4 3.561E-3 2.478E-2
9.258E-2
 2 58
27 int:POLA1 POLA1 interactions 1.853E-4 4.048E-3 2.817E-2
1.093E-1
 2 63
28 int:DMAP1 DMAP1 interactions 2.421E-4 4.926E-3 3.428E-2
1.429E-1
 2 72
29 int:RFC2 RFC2 interactions 2.421E-4 4.926E-3 3.428E-2
1.429E-1
 2 72
30 int:POLDIP2 POLDIP2 interactions 2.558E-4 5.030E-3 3.500E-2
1.509E-1
 2 74
31 int:RFC5 RFC5 interactions 2.990E-4 5.690E-3 3.959E-2
1.764E-1
 2 80
32 int:RFC1 RFC1 interactions 3.296E-4 5.824E-3 4.052E-2
1.945E-1
 2 84
33 int:HUS1 HUS1 interactions 3.296E-4 5.824E-3 4.052E-2
1.945E-1
 2 84
34 int:ASF1A ASF1A interactions 3.455E-4 5.824E-3 4.052E-2
2.038E-1
 2 86
35 int:H3F3B H3F3B interactions 3.455E-4 5.824E-3 4.052E-2
2.038E-1
 2 86
36 int:RPA1 RPA1 interactions 4.129E-4 6.768E-3 4.709E-2
2.436E-1
 3 497
37 int:MSH6 MSH6 interactions 5.146E-4 7.990E-3
5.560E-2
3.036E-1
 2 105
38 int:UHRF2 UHRF2 interactions 5.146E-4 7.990E-3
5.560E-2
3.036E-1
 2 105
39 int:DNMT1 DNMT1 interactions 5.957E-4 9.012E-3
6.271E-2
3.515E-1
 2 113
40 int:TEAD2 TEAD2 interactions 6.276E-4 9.258E-3
6.442E-2
3.703E-1
 2 116
41 int:MTA1 MTA1 interactions 7.283E-4 1.048E-2
7.292E-2
4.297E-1
 2 125
42 int:MCM4 MCM4 interactions 8.738E-4 1.228E-2
8.541E-2
5.156E-1
 2 137
43 int:SMARCAD1 SMARCAD1 interactions 9.647E-4 1.324E-2
9.211E-2
5.692E-1
 2 144
44 int:MSH2 MSH2 interactions 1.060E-3 1.421E-2
9.891E-2
6.254E-1
 2 151
45 int:SOX12 SOX12 interactions 1.355E-3 1.638E-2
1.140E-1
7.995E-1
 1 4
46 int:SBNO2 SBNO2 interactions 1.355E-3 1.638E-2
1.140E-1
7.995E-1
 1 4
47 int:PARPBP PARPBP interactions 1.355E-3 1.638E-2
1.140E-1
7.995E-1
 1 4
48 int:ATG9B ATG9B interactions 1.355E-3 1.638E-2
1.140E-1
7.995E-1
 1 4
49 int:SET SET interactions 1.372E-3 1.638E-2
1.140E-1
8.096E-1
 2 172
50 int:H3F3A H3F3A interactions 1.388E-3 1.638E-2
1.140E-1
8.189E-1
 2 173
Show 45 more annotations

10: Cytoband [Display Chart] 5 input genes in category / 5 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 11q14 11q14 1.730E-3 6.125E-3 1.399E-2 8.650E-3 1 12
2 21q22.13 21q22.13 2.450E-3 6.125E-3 1.399E-2 1.225E-2 1 17
3 7p13 7p13 5.901E-3 9.835E-3 2.246E-2 2.950E-2 1 41
4 5q31 5q31 1.648E-2 2.060E-2 4.704E-2
8.240E-2
 1 115
5 19p13.3 19p13.3 3.513E-2 3.513E-2
8.021E-2
1.756E-1
 1 247

11: Transcription Factor Binding Site [Display Chart] 2 input genes in category / 19 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GTTRYCATRR UNKNOWN GTTRYCATRR UNKNOWN 2.603E-2 4.932E-2
1.750E-1
4.946E-1
 1 128
2 SGCGSSAAA V$E2F1DP2 01 SGCGSSAAA V$E2F1DP2 01 2.664E-2 4.932E-2
1.750E-1
5.061E-1
 1 131
3 V$E2F1 Q6 V$E2F1 Q6 3.671E-2 4.932E-2
1.750E-1
6.975E-1
 1 181
4 V$E2F Q6 V$E2F Q6 3.691E-2 4.932E-2
1.750E-1
7.013E-1
 1 182
5 V$E2F1DP2 01 V$E2F1DP2 01 3.731E-2 4.932E-2
1.750E-1
7.090E-1
 1 184
6 V$E2F 02 V$E2F 02 3.731E-2 4.932E-2
1.750E-1
7.090E-1
 1 184
7 V$E2F Q4 V$E2F Q4 3.731E-2 4.932E-2
1.750E-1
7.090E-1
 1 184
8 V$E2F1DP1 01 V$E2F1DP1 01 3.731E-2 4.932E-2
1.750E-1
7.090E-1
 1 184
9 V$E2F4DP2 01 V$E2F4DP2 01 3.731E-2 4.932E-2
1.750E-1
7.090E-1
 1 184
10 V$E2F1DP1RB 01 V$E2F1DP1RB 01 3.731E-2 4.932E-2
1.750E-1
7.090E-1
 1 184
11 V$E2F1 Q6 01 V$E2F1 Q6 01 3.832E-2 4.932E-2
1.750E-1
7.280E-1
 1 189
12 V$E2F4DP1 01 V$E2F4DP1 01 3.832E-2 4.932E-2
1.750E-1
7.280E-1
 1 189
13 V$E2F1 Q3 V$E2F1 Q3 3.852E-2 4.932E-2
1.750E-1
7.318E-1
 1 190
14 V$HMGIY Q6 V$HMGIY Q6 3.932E-2 4.932E-2
1.750E-1
7.471E-1
 1 194
15 V$AP2 Q6 V$AP2 Q6 4.073E-2 4.932E-2
1.750E-1
7.738E-1
 1 201
16 V$MTF1 Q4 V$MTF1 Q4 4.273E-2 4.932E-2
1.750E-1
8.119E-1
 1 211
17 V$IRF1 Q6 V$IRF1 Q6 4.413E-2 4.932E-2
1.750E-1
8.385E-1
 1 218
Show 12 more annotations

12: Gene Family [Display Chart] 4 input genes in category / 4 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 535 DNA polymerases genenames.org 9.158E-6 3.663E-5 7.632E-5 3.663E-5 2 23
2 622 Kinesins|Protein phosphatase 1 regulatory subunits genenames.org 1.008E-2 2.015E-2 4.198E-2 4.030E-2 1 46

13: Coexpression [Display Chart] 6 input genes in category / 836 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M9372 Genes involved in DNA replication, compiled manually by the authors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.576E-11 4.661E-8 3.406E-7 4.661E-8 5 146
2 M11563 Genes involved in DNA repair, compiled manually by the authors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.532E-10 2.312E-7 1.690E-6 4.625E-7 5 230
3 M2156 Genes up-regulated in MCF7 cells (breast cancer) at 24 h of estradiol [PubChem=5757] treatment. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.098E-9 8.632E-7 6.307E-6 2.590E-6 5 324
4 M2074 Genes periodically expressed in synchronized HeLa cells (cervical carcinoma), with peak during the G1/S phase of cell cycle. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.323E-8 4.855E-6 3.548E-5 1.942E-5 4 147
5 M4523 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 8.018E-8 1.341E-5 9.795E-5 6.703E-5 4 200
6 20548326-Table4 Human Stomach Bonelli10 61genes GeneSigDB 3.298E-7 4.595E-5 3.357E-4 2.757E-4 3 60
7 M15969 Cluster 1: genes up-regulated by RB1, CDNK2A [GeneID=1029;5925], and one of the E2Fs (E2F1, E2F2, or E2F3 [GeneID=1869;1870;1871]). MSigDB C2: CGP Curated Gene Sets (v6.0) 5.270E-7 5.999E-5 4.383E-4 4.405E-4 3 70
8 M10739 Genes down-regulated in ANBL-6 cell line (multiple myeloma, MM) expressing a constantly active form of NRAS [GeneID=4893] off a plasmid vector compared to those grown in the presence of IL6 [GeneID=3569]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.740E-7 5.999E-5 4.383E-4 4.799E-4 3 72
9 15260889-TableS2a Human Breast Dairkee04 479genes GeneSigDB 9.012E-7 8.371E-5 6.116E-4 7.534E-4 4 366
10 M7715 Top 100 genes negatively associated with T-cell acute lymphoblastic leukemia MLL T-ALL) expressing MLL-ENL fusion [GeneID=4297;4298]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.019E-6 8.516E-5 6.222E-4 8.516E-4 3 87
11 M9516 Genes constituting the BRCA2-PCC network of transcripts whose expression positively correlated (Pearson correlation coefficient, PCC >= 0.4) with that of BRCA2 [GeneID=675] across a compendium of normal tissues. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.605E-6 1.220E-4 8.913E-4 1.342E-3 4 423
12 15896717-Table6 Human Leukemia Bal05 15genes GeneSigDB 5.876E-6 4.093E-4 2.991E-3 4.912E-3 2 15
13 M7551 Genes down-regulated in double positive thymocytes stimulated by anti-CD3: wildtype versus ELK1 [GeneID=2002] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.230E-5 6.139E-4 4.486E-3 1.028E-2 3 199
14 M4587 Genes down-regulated in comparison of naive T cells at day 0 versus CD25+ regulatory T cell (Treg) treated with IL4 [GeneID=3565] at day 3. MSigDB C7: Immunologic Signatures (v6.0) 1.248E-5 6.139E-4 4.486E-3 1.044E-2 3 200
15 M5925 Genes encoding cell cycle related targets of E2F transcription factors. MSigDB H: Hallmark Gene Sets (v6.0) 1.248E-5 6.139E-4 4.486E-3 1.044E-2 3 200
16 M9767 Genes up-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Th1 versus Ly6c low CXCR5- [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.248E-5 6.139E-4 4.486E-3 1.044E-2 3 200
17 M8325 Genes down-regulated in follicular helper T cells: BCL6 [GeneID=604] high versus BCL6 [GeneID=604] low. MSigDB C7: Immunologic Signatures (v6.0) 1.248E-5 6.139E-4 4.486E-3 1.044E-2 3 200
18 11861292-Table2 Human BoneMarrow Zhan02 30genes GeneSigDB 2.268E-5 1.053E-3 7.697E-3 1.896E-2 2 29
19 M17405 Top genes up-regulated in MM4 vs MM1 subgroup of multiple myeloma samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.430E-5 1.069E-3 7.812E-3 2.032E-2 2 30
20 M123 Genes constituting the PluriNet protein-protein network shared by the pluripotent cells (embryonic stem cells, embryonical carcinomas and induced pluripotent cells). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.152E-5 1.736E-3 1.268E-2 3.471E-2 3 299
21 M19745 Genes down-regulated in mature plasma cells compared with plasmablastic B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.536E-5 1.806E-3 1.319E-2 3.792E-2 3 308
22 M854 Genes whose expression profile is specific to Cluster III of urothelial cell carcinoma (UCC) tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.470E-5 2.079E-3 1.519E-2 4.573E-2 3 328
23 11559565-Table2 Human Brain Rickman01 50genes GeneSigDB 6.027E-5 2.158E-3 1.577E-2
5.039E-2
 2 47
24 M2879 Selected genes down-regulated in response to the Ras inhibitor salirasib [PubChem=5469318] in a panel of cancer cell lines with constantly active HRAS [GeneID=3265]. MSigDB C2: CGP Curated Gene Sets (v6.0) 6.195E-5 2.158E-3 1.577E-2
5.179E-2
 3 342
25 M2257 Cellular genes up-regulated in forskin fibroblasts by expression of CMV EI86 protein off an adenovirus vector. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.854E-5 3.154E-3 2.304E-2
8.238E-2
 2 60
26 M2431 DNA repair and replication genes up-regulated in melanoma patients who will relapse vs patients who will not. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.019E-4 3.154E-3 2.304E-2
8.516E-2
 2 61
27 12941627-table1a Mouse StemCell Karsten03 71genes GeneSigDB 1.019E-4 3.154E-3 2.304E-2
8.516E-2
 2 61
28 14750170-Table2 Mouse Intestine DeGiovanni04 68genes GeneSigDB 1.157E-4 3.455E-3 2.525E-2
9.675E-2
 2 65
29 15958547-SuppTable3 Human Pancreas Qian05 94genes GeneSigDB 1.343E-4 3.871E-3 2.828E-2
1.123E-1
 2 70
30 15489886-TableS1b Human Sarcoma Mason04 549genes GeneSigDB 1.532E-4 4.270E-3 3.120E-2
1.281E-1
 3 464
31 15374877-Table2 Human StemCell Manalo05 108genes GeneSigDB 1.799E-4 4.818E-3 3.520E-2
1.504E-1
 2 81
32 19061838-TableS16 Human Viral Cairo08 88genes GeneSigDB 1.844E-4 4.818E-3 3.520E-2
1.542E-1
 2 82
33 12874028-Table1 Human Esophagus Barrett03 104genes GeneSigDB 2.476E-4 6.272E-3 4.582E-2
2.070E-1
 2 95
34 M18506 Genes down-regulated in the ANBL-6 cell line (multiple myeloma, MM) after withdrawal of IL6 [GeneID=3569]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.634E-4 6.478E-3 4.733E-2
2.202E-1
 2 98
35 M1836 Up-regulated genes in NMuMG cells (mammary epithelium) after stimulation with WNT3A [GeneID=89780]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.440E-4 8.216E-3
6.003E-2
2.876E-1
 2 112
36 M2895 Genes up-regulated in MEF cells (embryonic fibroblasts) isolated from RB1 [GeneID=5925] knockout mice: chronic loss of function (LOF) of RB1. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.626E-4 8.398E-3
6.136E-2
3.031E-1
 2 115
37 M15305 Genes constituting the BRCA-centered network (BCN). MSigDB C2: CGP Curated Gene Sets (v6.0) 3.753E-4 8.398E-3
6.136E-2
3.137E-1
 2 117
38 M18086 'Cancer prone response profile' (CPRP): genes common to estradiol and bisphenol A [PubChem=5757;6623] response of epithelial cell cultures from patients at high risk of breast cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.817E-4 8.398E-3
6.136E-2
3.191E-1
 2 118
39 M6866 Genes down-regulated in PaCa44 and CFPAC1 cells (pancreatic cancer) after treatment with decitabine [PubChem=451668], a DNA hypomethylating agent similar to azacitidine [PubChem=9444]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.080E-4 8.745E-3
6.390E-2
3.411E-1
 2 122
40 M2802 Genes up-regulated in primary keratinocytes from RB1 and RBL1 [Gene ID=5925, 5933] skin specific knockout mice. MSigDB C6: Oncogenic Signatures (v6.0) 5.291E-4 9.593E-3
7.009E-2
4.423E-1
 2 139
41 M15664 The 'Cervical Cancer Proliferation Cluster' (CCPC): genes whose expression in cervical carcinoma positively correlates with that of the HPV E6 and E7 oncogenes; they are also differentially expressed according to disease outcome. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.367E-4 9.593E-3
7.009E-2
4.487E-1
 2 140
42 M6506 Genes up-regulated by MYC [GeneID=4609] and whose promoters are bound by MYC, according to MYC Target Gene Database. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.598E-4 9.593E-3
7.009E-2
4.680E-1
 2 143
43 M10633 Genes which comprise the top 1% of highly interconnected genes (major hubs) that account for most of gene interactions in the reconstructed regulatory networks from expression profiles in B lymphocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.598E-4 9.593E-3
7.009E-2
4.680E-1
 2 143
44 M2114 Set 'Proliferation Cluster': genes defined in human breast tumor expression data. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.914E-4 9.593E-3
7.009E-2
4.944E-1
 2 147
45 M5898 Genes involved in DNA repair. MSigDB H: Hallmark Gene Sets (v6.0) 6.157E-4 9.593E-3
7.009E-2
5.147E-1
 2 150
46 12925741-Figure8 Human Lymphoma Jenner03 279genes GeneSigDB 6.404E-4 9.593E-3
7.009E-2
5.354E-1
 2 153
47 M13108 Genes down-regulated in Wilm's tumor samples compared to fetal kidney. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.263E-4 9.593E-3
7.009E-2
6.072E-1
 2 163
48 19043454-TableS2 Human Breast Thorner09 217genes GeneSigDB 7.622E-4 9.593E-3
7.009E-2
6.372E-1
 2 167
49 M18811 Genes constituting the XPRSS-Int network: intersection of genes whose expression correlates with BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200] in a compendium of normal tissues. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.713E-4 9.593E-3
7.009E-2
6.448E-1
 2 168
50 M4288 Genes up-regulated in MCF10A cells (breast cancer) grown at low (mesenchymal phenotype) compared to those grown at high (epithelial, basal-like phenotype) confluency. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.845E-4 9.593E-3
7.009E-2
7.394E-1
 2 180
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 6 input genes in category / 333 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/Slamf1-positive multipotent progenitor cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/Slamf1-positive multipotent progenitor cell Tabula Muris Consortium 8.404E-8 2.799E-5 1.787E-4 2.799E-5 4 191
2 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Neurogenesis Top 200 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Neurogenesis Top 200 6.643E-7 5.531E-5 3.532E-4 2.212E-4 4 320
3 Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Neurogenesis Subtype Sox4.Hist1h2al Top 200 Genes Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Neurogenesis Subtype Sox4.Hist1h2al Top 200 Genes 6.643E-7 5.531E-5 3.532E-4 2.212E-4 4 320
4 BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature.Sox4 Neurogenesis.neurons.immature.Sox4 Subtype Neurogenesis.neurons.immature.Sox4.Hist1h2al Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Neurogenesis.neurons.immature.Sox4 Neurogenesis.neurons.immature.Sox4 Subtype Neurogenesis.neurons.immature.Sox4.Hist1h2al Top 200 Genes BrainMap 6.643E-7 5.531E-5 3.532E-4 2.212E-4 4 320
5 Mouse Cell Atlas Mouse Regional GI Enterocytes Transit amplifying Enterocyte progenitor Transit amplifying Enterocyte progenitor Subtype transit amplifying progenitor Ileum Top 200 Genes Mouse Cell Atlas Mouse Regional GI Enterocytes Transit amplifying Enterocyte progenitor Transit amplifying Enterocyte progenitor Subtype transit amplifying progenitor Ileum Top 200 Genes Mouse Cell Atlas 7.047E-5 3.470E-3 2.216E-2 2.346E-2 3 337
6 GSM791154 500 alpha beta T cells, T.DN4.Th, Lin-/lo CD25- CD44- CD28+, Thymus, avg-3 Immgen.org, GSE15907 9.756E-5 3.470E-3 2.216E-2 3.249E-2 3 376
7 10X Human 8K PBMC unknown Subtype unknown-T cell CD4 - B Top 200 Genes 10X Human 8K PBMC unknown Subtype unknown-T cell CD4 - B Top 200 Genes 1.104E-4 3.470E-3 2.216E-2 3.677E-2 3 392
8 GSM791143 500 alpha beta T cells, preT.DN3-4.Th, Lin-/lo CD25int CD44- CD28+, Thymus, avg-3 Immgen.org, GSE15907 1.146E-4 3.470E-3 2.216E-2 3.817E-2 3 397
9 GSM791119 500 Stem Cells, SC.GMP.BM, Lineage- sca1- ckithi CD34+ FcgRhi, Bone marrow, avg-3 Immgen.org, GSE15907 1.225E-4 3.470E-3 2.216E-2 4.080E-2 3 406
10 GSM791149 500 alpha beta T cells, preT.DN3B.Th, Lin-/lo CD25hi CD44- CD28+, Thymus, avg-3 Immgen.org, GSE15907 1.289E-4 3.470E-3 2.216E-2 4.292E-2 3 413
11 GSM791134 500 alpha beta T cells, preT.DN2-3.Th, Lin-/lo CD25hi CD44Int, Thymus, avg-2 Immgen.org, GSE15907 1.307E-4 3.470E-3 2.216E-2 4.354E-2 3 415
12 GSM476664 500 gamma delta T cells, Tgd.vg3+24alo.e17.Th, TCRd+ Vg3+ CD24-, Fetal Thymus, avg-3 Immgen.org, GSE15907 1.345E-4 3.470E-3 2.216E-2 4.479E-2 3 419
13 GSM791136 500 alpha beta T cells, preT.DN2.Th, Lin-/lo CD25hi CD44+ cKit+, Thymus, avg-3 Immgen.org, GSE15907 1.355E-4 3.470E-3 2.216E-2 4.511E-2 3 420
14 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Overall Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Overall Top 100 Genes 3.018E-4 7.179E-3 4.585E-2
1.005E-1
 2 99
15 gudmap dev gonad e11.5 M GonadVasMes Flk k3 1000 dev gonad e11.5 M GonadVasMes Flk k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse ST 1.0 4.655E-4 1.033E-2
6.600E-2
1.550E-1
 2 123
16 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma/Malignant Peripheral Nerve Sheath Tumors /1 Sample Type by Project: Shred 1/TCGA-Bone and Soft Tissue/Sarcoma/Malignant Peripheral Nerve Sheath Tumors /1 TCGA-Bone and Soft Tissue 6.283E-4 1.227E-2
7.837E-2
2.092E-1
 2 143
17 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.3 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.3 Top 100 Genes 6.548E-4 1.227E-2
7.837E-2
2.181E-1
 2 146
18 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.2 Top 100 Genes 6.910E-4 1.227E-2
7.837E-2
2.301E-1
 2 150
19 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.1 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.1 Top 100 Genes 7.002E-4 1.227E-2
7.837E-2
2.332E-1
 2 151
20 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.0.2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.0.2 Top 100 Genes 7.855E-4 1.268E-2
8.098E-2
2.616E-1
 2 160
21 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.0.4 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.0.4 Top 100 Genes 8.451E-4 1.268E-2
8.098E-2
2.814E-1
 2 166
22 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s2 intermediate neurons Subtype intermediate neurons s2 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s2 intermediate neurons Subtype intermediate neurons s2 Top 100 Genes 8.655E-4 1.268E-2
8.098E-2
2.882E-1
 2 168
23 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.5 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.5 Top 100 Genes 8.757E-4 1.268E-2
8.098E-2
2.916E-1
 2 169
24 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s3 intermediate neurons Subtype intermediate neurons s3 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Subtype intermediate neurons s3 intermediate neurons Subtype intermediate neurons s3 Top 100 Genes 9.385E-4 1.293E-2
8.258E-2
3.125E-1
 2 175
25 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.4 Top 100 Genes 6mo cortical organoids wt 6mo cortical organoids wt Intermediate.0 Intermediate.0 Subtype int.01.4 Top 100 Genes 9.707E-4 1.293E-2
8.258E-2
3.232E-1
 2 178
26 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Erythroblast/Kidney Normal-Cortex Wilms Erythroblast Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Erythroblast/Kidney Normal-Cortex Wilms Erythroblast Adult, Development, and Cancer types 1.116E-3 1.391E-2
8.885E-2
3.717E-1
 2 191
27 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/megakaryocyte-erythroid progenitor cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Marrow/megakaryocyte-erythroid progenitor cell Tabula Muris Consortium 1.128E-3 1.391E-2
8.885E-2
3.756E-1
 2 192
28 Facebase ST1 e10.5 Emin MedialNasal 500 3 e10.5 Emin MedialNasal top-relative-expression-ranked 500 3 FaceBase_ST1 1.754E-3 2.086E-2
1.332E-1
5.840E-1
 2 240
29 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC-cycle Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ HSC-cycle Top 200 Genes 2.669E-3 3.042E-2
1.943E-1
8.889E-1
 2 297
30 Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ MultiLin Top 200 Genes Human Cell Atlas Human Cell Atlas HSC HSC Subtype CD34+ MultiLin Top 200 Genes 2.740E-3 3.042E-2
1.943E-1
9.126E-1
 2 301
31 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eProg Subtype eProg2b Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eProg Subtype eProg2b Top 200 Genes GSE76381_ESMoleculeCountsPMLog2 3.401E-3 3.291E-2
2.102E-1
1.000E0
 2 336
32 10X Human 8K PBMC Immune Subtype Immune-STMN1 TK1 KIAA0101 A Top 200 Genes 10X Human 8K PBMC Immune Subtype Immune-STMN1 TK1 KIAA0101 A Top 200 Genes 3.501E-3 3.291E-2
2.102E-1
1.000E0
 2 341
33 BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Dlx1 Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Dlx1 Top 200 Genes BrainMap 3.623E-3 3.291E-2
2.102E-1
1.000E0
 2 347
34 GSM538358 500 B cells, proB.FrBC.FL, CD19+ IgM- CD43+ CD24+ AA4.1+ CD45R+, Fetal Liver, avg-3 Immgen.org, GSE15907 4.785E-3 3.291E-2
2.102E-1
1.000E0
 2 400
35 GSM791108 500 Stem Cells, SC.MEP.BM, Lineage- Kit+ Sca1- CD34- FcgR-/low, Bone marrow, avg-2 Immgen.org, GSE15907 4.808E-3 3.291E-2
2.102E-1
1.000E0
 2 401
36 GSM791114 500 Stem Cells, SC.CDP.BM, Sca1- Flt3+ MCSFR+ cKitlo, Bone marrow, avg-3 Immgen.org, GSE15907 4.808E-3 3.291E-2
2.102E-1
1.000E0
 2 401
37 GSM854317 500 Myeloid Cells, MF.BM, B220neg CD3neg Ly-6C/Glo CD115int F4/80+, Bone marrow, avg-3 Immgen.org, GSE15907 4.808E-3 3.291E-2
2.102E-1
1.000E0
 2 401
38 GSM791105 500 Stem Cells, SC.MDP.BM, Sca1- Flt3+ MCSFR+ cKithi, Bone marrow, avg-3 Immgen.org, GSE15907 4.832E-3 3.291E-2
2.102E-1
1.000E0
 2 402
39 GSM605898 500 alpha beta T cells, T.8Eff.Sp.OT1.d6.LisOva, CD8+ CD45.1+, Spleen, avg-3 Immgen.org, GSE15907 4.832E-3 3.291E-2
2.102E-1
1.000E0
 2 402
40 GSM791129 500 B cells, MLP.BM, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R- CD, Bone marrow, avg-2 Immgen.org, GSE15907 4.879E-3 3.291E-2
2.102E-1
1.000E0
 2 404
41 GSM791139 500 alpha beta T cells, preT.DN2A.Th, Lin-/lo CD25hi CD44+ cKithi, Thymus, avg-2 Immgen.org, GSE15907 4.997E-3 3.291E-2
2.102E-1
1.000E0
 2 409
42 GSM399452 500 B cells, preB.FrC.BM, CD19+ IgM- CD45R+ CD43+ HSA+, Bone marrow, avg-3 Immgen.org, GSE15907 4.997E-3 3.291E-2
2.102E-1
1.000E0
 2 409
43 GSM538387 500 alpha beta T cells, T.8Eff.Sp.OT1.d5.VSVOva, CD8+ CD45.1+, Spleen, avg-3 Immgen.org, GSE15907 5.021E-3 3.291E-2
2.102E-1
1.000E0
 2 410
44 GSM476660 500 gamma delta T cells, Tgd.vg2+24ahi.e17.Th, TCRd+ Vg2+ CD24+, Fetal Thymus, avg-3 Immgen.org, GSE15907 5.117E-3 3.291E-2
2.102E-1
1.000E0
 2 414
45 GSM854335 500 alpha beta T cells, preT.ETP.Th, Lin-/lo CD25- CD44+ cKit+, Thymus, avg-3 Immgen.org, GSE15907 5.142E-3 3.291E-2
2.102E-1
1.000E0
 2 415
46 GSM399403 500 alpha beta T cells, T.ISP.Th, 4- 8+ TCR-/lo 24hi, Thymus, avg-3 Immgen.org, GSE15907 5.190E-3 3.291E-2
2.102E-1
1.000E0
 2 417
47 GSM538350 500 B cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate CD45R- AA4.1+ CD, Fetal Liver, avg-1 Immgen.org, GSE15907 5.214E-3 3.291E-2
2.102E-1
1.000E0
 2 418
48 GSM538348 500 B cells, proB.CLP.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R- CD, Fetal Liver, avg-2 Immgen.org, GSE15907 5.239E-3 3.291E-2
2.102E-1
1.000E0
 2 419
49 GSM791141 500 alpha beta T cells, preT.DN2B.Th, Lin-/lo CD25hi CD44+ cKitint, Thymus, avg-2 Immgen.org, GSE15907 5.263E-3 3.291E-2
2.102E-1
1.000E0
 2 420
50 GSM538355 500 B cells, proB.FrA.FL, CD19- IgM- CD43+ CD24intermediate AA4.1+ CD45R+ CD, Fetal Liver, avg-2 Immgen.org, GSE15907 5.312E-3 3.291E-2
2.102E-1
1.000E0
 2 422
Show 45 more annotations

15: Computational [Display Chart] 6 input genes in category / 95 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M6330 MODULE 158 DNA replication. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.353E-9 2.274E-7 1.168E-6 4.135E-7 4 43
2 M15402 MODULE 125 Genes in the cancer module 125. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.788E-9 2.274E-7 1.168E-6 4.548E-7 4 44
3 M4550 MODULE 252 TFs and nuclear. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.381E-6 1.387E-4 7.126E-4 4.162E-4 4 237
4 M17658 MODULE 198 Genes in the cancer module 198. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.164E-5 2.766E-4 1.420E-3 1.106E-3 4 303
5 M14843 MODULE 98 Genes in the cancer module 98. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.262E-5 5.475E-4 2.812E-3 3.099E-3 4 393
6 M8921 MODULE 53 Cell line expressed genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.674E-5 5.475E-4 2.812E-3 3.490E-3 4 405
7 M5869 MODULE 90 Genes in the cancer module 90. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.034E-5 5.475E-4 2.812E-3 3.833E-3 2 17
8 M4657 MODULE 189 Genes in the cancer module 189. MSigDb: C4 - CM: Cancer Modules (v6.0) 7.493E-5 8.898E-4 4.570E-3 7.118E-3 2 23
9 M17337 MODULE 127 Genes in the cancer module 127. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.618E-5 1.015E-3 5.214E-3 9.137E-3 2 26
10 M6479 MODULE 105 Genes in the cancer module 105. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.491E-4 1.417E-3 7.277E-3 1.417E-2 3 200
11 M5468 MODULE 54 Cell cycle (expression cluster). MSigDb: C4 - CM: Cancer Modules (v6.0) 3.318E-4 2.865E-3 1.472E-2 3.152E-2 3 262
12 M17234 MORF MSH2 Neighborhood of MSH2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.365E-4 4.247E-3 2.182E-2
5.097E-2
 2 61
13 M4409 MODULE 17 Genes in the cancer module 17. MSigDb: C4 - CM: Cancer Modules (v6.0) 8.931E-4 6.527E-3 3.352E-2
8.485E-2
 3 367
14 M9199 MODULE 3 Genes in the cancer module 3. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.027E-3 6.971E-3 3.580E-2
9.759E-2
 3 385
15 M12108 MODULE 118 cell line expressed genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.234E-3 7.816E-3 4.015E-2
1.172E-1
 3 410
16 M956 MODULE 8 Genes in the cancer module 8. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.333E-3 7.915E-3 4.065E-2
1.266E-1
 3 421
17 M10190 MODULE 52 Cell line expressed genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.447E-3 8.084E-3 4.152E-2
1.374E-1
 3 433
18 M18856 MODULE 456 B lymphoma expression clusters. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.830E-3 9.657E-3 4.960E-2
1.738E-1
 2 113
19 M949 MODULE 244 Response to DNA damage. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.930E-3 2.465E-2
1.266E-1
4.683E-1
 2 187
20 M15264 MODULE 203 Genes in the cancer module 203. MSigDb: C4 - CM: Cancer Modules (v6.0) 9.529E-3 4.526E-2
2.325E-1
9.052E-1
 1 16
21 M13419 MORF BUB3 Neighborhood of BUB3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.050E-2 4.752E-2
2.441E-1
9.979E-1
 2 276
Show 16 more annotations

16: MicroRNA [Display Chart] 6 input genes in category / 269 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-6780b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.295E-5 3.662E-3 2.261E-2 6.173E-3 2 90
2 hsa-miR-6765-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.723E-5 3.662E-3 2.261E-2 7.324E-3 2 98
3 hsa-miR-1304-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.174E-5 4.639E-3 2.864E-2 1.392E-2 2 135
4 hsa-miR-10a*:mirSVR highEffct hsa-miR-10a*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 3.120E-4 1.725E-2
1.065E-1
8.394E-2
 2 332
5 hsa-miR-155-5p:TargetScan hsa-miR-155-5p TargetScan 4.233E-4 1.725E-2
1.065E-1
1.139E-1
 2 387
6 hsa-miR-4793-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.934E-4 1.725E-2
1.065E-1
1.327E-1
 2 418
7 hsa-miR-4252:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.839E-4 1.725E-2
1.065E-1
1.571E-1
 2 455
8 hsa-miR-26a-5p:Functional MTI Functional MTI miRTarbase 5.890E-4 1.725E-2
1.065E-1
1.584E-1
 2 457
9 hsa-miR-7703:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.333E-4 1.725E-2
1.065E-1
1.704E-1
 2 474
10 hsa-miR-508-5p:Functional MTI Functional MTI miRTarbase 6.413E-4 1.725E-2
1.065E-1
1.725E-1
 2 477
11 hsa-miR-933:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.743E-3 2.837E-2
1.751E-1
4.689E-1
 1 21
12 hsa-miR-5687:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.489E-3 2.837E-2
1.751E-1
6.696E-1
 1 30
13 hsa-miR-374c-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.986E-3 2.837E-2
1.751E-1
8.033E-1
 1 36
14 hsa-miR-6821-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.152E-3 2.837E-2
1.751E-1
8.479E-1
 1 38
15 hsa-miR-4288:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.152E-3 2.837E-2
1.751E-1
8.479E-1
 1 38
16 hsa-miR-154-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.235E-3 2.837E-2
1.751E-1
8.702E-1
 1 39
17 hsa-miR-3945:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.401E-3 2.837E-2
1.751E-1
9.148E-1
 1 41
18 hsa-miR-1251-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.401E-3 2.837E-2
1.751E-1
9.148E-1
 1 41
19 hsa-miR-632:Functional MTI Functional MTI miRTarbase 3.401E-3 2.837E-2
1.751E-1
9.148E-1
 1 41
20 hsa-miR-1231:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.732E-3 2.837E-2
1.751E-1
1.000E0
 1 45
21 hsa-miR-517-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.897E-3 2.837E-2
1.751E-1
1.000E0
 1 47
22 hsa-miR-4728-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.897E-3 2.837E-2
1.751E-1
1.000E0
 1 47
23 hsa-miR-6793-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.063E-3 2.837E-2
1.751E-1
1.000E0
 1 49
24 hsa-miR-4799-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.146E-3 2.837E-2
1.751E-1
1.000E0
 1 50
25 hsa-miR-5580-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.228E-3 2.837E-2
1.751E-1
1.000E0
 1 51
26 hsa-miR-4720-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.228E-3 2.837E-2
1.751E-1
1.000E0
 1 51
27 hsa-miR-5588-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.228E-3 2.837E-2
1.751E-1
1.000E0
 1 51
28 hsa-miR-5681b:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.394E-3 2.837E-2
1.751E-1
1.000E0
 1 53
29 hsa-miR-3667-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.394E-3 2.837E-2
1.751E-1
1.000E0
 1 53
30 hsa-miR-487a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.477E-3 2.837E-2
1.751E-1
1.000E0
 1 54
31 hsa-miR-1-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.477E-3 2.837E-2
1.751E-1
1.000E0
 1 54
32 hsa-miR-6759-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.642E-3 2.837E-2
1.751E-1
1.000E0
 1 56
33 hsa-miR-581:Functional MTI Functional MTI miRTarbase 4.725E-3 2.837E-2
1.751E-1
1.000E0
 1 57
34 hsa-miR-4642:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.973E-3 2.837E-2
1.751E-1
1.000E0
 1 60
35 hsa-miR-6741-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.056E-3 2.837E-2
1.751E-1
1.000E0
 1 61
36 hsa-miR-331-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.837E-2
1.751E-1
1.000E0
 1 63
37 hsa-miR-6866-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.221E-3 2.837E-2
1.751E-1
1.000E0
 1 63
38 hsa-miR-4678:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.552E-3 2.837E-2
1.751E-1
1.000E0
 1 67
39 hsa-miR-6862-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.635E-3 2.837E-2
1.751E-1
1.000E0
 1 68
40 hsa-miR-4253:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.717E-3 2.837E-2
1.751E-1
1.000E0
 1 69
41 hsa-miR-219a-1-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.717E-3 2.837E-2
1.751E-1
1.000E0
 1 69
42 hsa-miR-5002-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.965E-3 2.837E-2
1.751E-1
1.000E0
 1 72
43 hsa-miR-4725-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.048E-3 2.837E-2
1.751E-1
1.000E0
 1 73
44 hsa-miR-4461:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.131E-3 2.837E-2
1.751E-1
1.000E0
 1 74
45 hsa-miR-1279:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.296E-3 2.837E-2
1.751E-1
1.000E0
 1 76
46 hsa-miR-888-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.378E-3 2.837E-2
1.751E-1
1.000E0
 1 77
47 hsa-miR-369-5p:mirSVR highEffct hsa-miR-369-5p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 6.709E-3 2.837E-2
1.751E-1
1.000E0
 1 81
48 hsa-miR-6854-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.874E-3 2.837E-2
1.751E-1
1.000E0
 1 83
49 hsa-miR-222-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.874E-3 2.837E-2
1.751E-1
1.000E0
 1 83
50 hsa-miR-3166:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.957E-3 2.837E-2
1.751E-1
1.000E0
 1 84
Show 45 more annotations

17: Drug [Display Chart] 6 input genes in category / 1153 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000105028 dg-8-AAF Stitch 1.660E-9 1.276E-6 9.735E-6 1.915E-6 3 11
2 CID000127308 BuAdATP Stitch 2.214E-9 1.276E-6 9.735E-6 2.552E-6 3 12
3 CID000123713 BuPdGTP Stitch 6.008E-8 2.309E-5 1.761E-4 6.928E-5 3 34
4 CID002824289 ML60218 Stitch 1.725E-7 3.315E-5 2.528E-4 1.989E-4 2 3
5 CID003541570 6-(p-tolylhydrazino)-2-thiouracil Stitch 1.725E-7 3.315E-5 2.528E-4 1.989E-4 2 3
6 CID000157374 AC1L4HWF Stitch 1.725E-7 3.315E-5 2.528E-4 1.989E-4 2 3
7 CID000131614 DCBG Stitch 3.450E-7 5.682E-5 4.334E-4 3.977E-4 2 4
8 CID000000625 AC1Q6S3R Stitch 5.718E-7 7.365E-5 5.617E-4 6.593E-4 3 71
9 CID000375119 NSC654259 Stitch 5.749E-7 7.365E-5 5.617E-4 6.628E-4 2 5
10 CID000368696 NSC639828 Stitch 8.622E-7 9.727E-5 7.420E-4 9.941E-4 2 6
11 CID000004156 methyl methanesulfonate Stitch 9.280E-7 9.727E-5 7.420E-4 1.070E-3 4 364
12 CID000065051 ddTTP Stitch 1.022E-6 9.823E-5 7.493E-4 1.179E-3 3 86
13 CID000000646 AC1Q6S3Y Stitch 1.173E-6 9.940E-5 7.582E-4 1.353E-3 3 90
14 CID000162025 H2-HPUra Stitch 1.207E-6 9.940E-5 7.582E-4 1.392E-3 2 7
15 CID000656414 2-hydroxydeoxyadenosine 5'-triphosphate Stitch 2.069E-6 1.491E-4 1.137E-3 2.385E-3 2 9
16 CID000066950 isocytosine Stitch 2.069E-6 1.491E-4 1.137E-3 2.385E-3 2 9
17 ctd:D006147 Guanine CTD 2.585E-6 1.656E-4 1.263E-3 2.981E-3 2 10
18 CID003062886 2-(p-n-butylanilino)-2'-deoxyadenosine Stitch 2.585E-6 1.656E-4 1.263E-3 2.981E-3 2 10
19 CID000000621 NSC82625 Stitch 4.259E-6 2.584E-4 1.971E-3 4.910E-3 3 138
20 CID000001151 AC1Q6S3S Stitch 4.641E-6 2.676E-4 2.041E-3 5.351E-3 3 142
21 CID000019518 denatonium Stitch 5.226E-6 2.739E-4 2.089E-3 6.025E-3 2 14
22 CID000452202 PMEGpp Stitch 5.226E-6 2.739E-4 2.089E-3 6.025E-3 2 14
23 CID005311341 ATP betaS Stitch 6.896E-6 3.457E-4 2.637E-3 7.951E-3 3 162
24 ctd:D018053 Arsenites CTD 7.807E-6 3.611E-4 2.754E-3 9.002E-3 2 17
25 CID000449615 AC1L9NBB Stitch 7.830E-6 3.611E-4 2.754E-3 9.027E-3 3 169
26 CID000429118 poly(vA Stitch 9.814E-6 3.902E-4 2.976E-3 1.132E-2 2 19
27 CID000163040 aucubigenin Stitch 9.814E-6 3.902E-4 2.976E-3 1.132E-2 2 19
28 CID000126441 5-ClAU Stitch 9.814E-6 3.902E-4 2.976E-3 1.132E-2 2 19
29 CID000130774 dercitin Stitch 9.814E-6 3.902E-4 2.976E-3 1.132E-2 2 19
30 CID003010960 AC1MHT6K Stitch 1.090E-5 3.918E-4 2.989E-3 1.257E-2 2 20
31 CID000454146 OXT-ATP Stitch 1.090E-5 3.918E-4 2.989E-3 1.257E-2 2 20
32 CID000002028 ATP,Gamma S Stitch 1.095E-5 3.918E-4 2.989E-3 1.263E-2 3 189
33 CID000000640 NSC23615 Stitch 1.166E-5 3.918E-4 2.989E-3 1.344E-2 3 193
34 CID000323259 parazoanthoxanthin A Stitch 1.205E-5 3.918E-4 2.989E-3 1.389E-2 2 21
35 CID000122664 AC1L3V16 Stitch 1.205E-5 3.918E-4 2.989E-3 1.389E-2 2 21
36 CID000072244 U-78036 Stitch 1.325E-5 3.918E-4 2.989E-3 1.528E-2 2 22
37 CID006438779 petasiphenol Stitch 1.325E-5 3.918E-4 2.989E-3 1.528E-2 2 22
38 CID000480107 AC1LA211 Stitch 1.325E-5 3.918E-4 2.989E-3 1.528E-2 2 22
39 CID006438404 BVdUTP Stitch 1.325E-5 3.918E-4 2.989E-3 1.528E-2 2 22
40 CID011840913 DB07328 Stitch 1.459E-5 4.205E-4 3.208E-3 1.682E-2 3 208
41 CID006857433 AC1OAGMB Stitch 1.583E-5 4.346E-4 3.315E-3 1.825E-2 2 24
42 CID005273539 BrVarafUTP Stitch 1.583E-5 4.346E-4 3.315E-3 1.825E-2 2 24
43 CID005287723 AC1NRA6E Stitch 1.721E-5 4.613E-4 3.519E-3 1.984E-2 2 25
44 CID000000593 NSC20261 Stitch 1.821E-5 4.772E-4 3.640E-3 2.100E-2 3 224
45 CID000027281 AC1L1CVV Stitch 1.864E-5 4.775E-4 3.642E-3 2.149E-2 2 26
46 CID000072188 araTTP Stitch 2.013E-5 5.045E-4 3.848E-3 2.320E-2 2 27
47 CID000506602 R)-PCV-TP Stitch 2.167E-5 5.316E-4 4.055E-3 2.499E-2 2 28
48 CID000023985 gold nanoparticles Stitch 2.323E-5 5.367E-4 4.094E-3 2.679E-2 3 243
49 CID003000477 UC-3 Stitch 2.327E-5 5.367E-4 4.094E-3 2.683E-2 2 29
50 CID000469173 AC1LAIP3 Stitch 2.327E-5 5.367E-4 4.094E-3 2.683E-2 2 29
Show 45 more annotations

18: Disease [Display Chart] 6 input genes in category / 355 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0026636 Mouth Diseases DisGeNET Curated 1.038E-5 3.684E-3 2.376E-2 3.684E-3 2 14
2 C0151779 Cutaneous Melanoma DisGeNET Curated 7.011E-5 1.208E-2
7.795E-2
 2.489E-2 3 250
3 C0001618 Tumors of Adrenal Cortex DisGeNET Curated 1.073E-4 1.208E-2
7.795E-2
 3.810E-2 2 44
4 C0278685 Ovarian epithelial cancer stage I DisGeNET BeFree 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
5 C0153560 Kaposi's sarcoma of skin DisGeNET BeFree 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
6 C4016019 DNA Ligase I Deficiency DisGeNET BeFree 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
7 C3161259 Pilar and trichilemmal cysts DisGeNET BeFree 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
8 C3273034 Moderately Differentiated Hepatocellular Carcinoma DisGeNET BeFree 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
9 C4014676 ATAXIA-TELANGIECTASIA-LIKE DISORDER 2 DisGeNET Curated 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
10 cv:CN197312 Ataxia-telangiectasia-like disorder 2 Clinical Variations 3.703E-4 1.208E-2
7.795E-2
1.314E-1
 1 1
11 C3887499 Renal cyst DisGeNET Curated 3.745E-4 1.208E-2
7.795E-2
1.329E-1
 2 82
12 C0341268 Disorder of small intestine DisGeNET BeFree 7.404E-4 1.877E-2
1.211E-1
2.628E-1
 1 2
13 C3898352 Mild Bronchopulmonary Dysplasia DisGeNET BeFree 7.404E-4 1.877E-2
1.211E-1
2.628E-1
 1 2
14 C0280201 stage, Kaposi's sarcoma DisGeNET BeFree 7.404E-4 1.877E-2
1.211E-1
2.628E-1
 1 2
15 C1839736 WILSON-TURNER X-LINKED MENTAL RETARDATION SYNDROME DisGeNET Curated 1.110E-3 2.319E-2
1.496E-1
3.942E-1
 1 3
16 C1846009 Intrauterine Growth Retardation, Metaphyseal Dysplasia, Adrenal Hypoplasia Congenita, And Genital Anomalies DisGeNET Curated 1.110E-3 2.319E-2
1.496E-1
3.942E-1
 1 3
17 C1370932 carcinoma of the renal pelvis and ureter DisGeNET BeFree 1.110E-3 2.319E-2
1.496E-1
3.942E-1
 1 3
18 C0010709 Cyst DisGeNET Curated 1.433E-3 2.502E-2
1.614E-1
5.089E-1
 2 161
19 C1412014 Infiltrating duct carcinoma DisGeNET BeFree 1.480E-3 2.502E-2
1.614E-1
5.255E-1
 1 4
20 C0334448 Cellular Blue Nevus DisGeNET BeFree 1.480E-3 2.502E-2
1.614E-1
5.255E-1
 1 4
21 C1336554 T-Cell and NK-Cell Neoplasm DisGeNET BeFree 1.480E-3 2.502E-2
1.614E-1
5.255E-1
 1 4
22 C1333878 B-Cell Lymphoma, Unclassifiable, with Features Intermediate between Diffuse Large B-Cell Lymphoma and Classical Hodgkin Lymphoma DisGeNET BeFree 1.850E-3 2.985E-2
1.926E-1
6.568E-1
 1 5
23 C0520573 Buffalo hump DisGeNET BeFree 2.220E-3 3.156E-2
2.036E-1
7.880E-1
 1 6
24 C1392224 Centrocytic lymphoma DisGeNET BeFree 2.220E-3 3.156E-2
2.036E-1
7.880E-1
 1 6
25 C0022660 Kidney Failure, Acute DisGeNET Curated 2.222E-3 3.156E-2
2.036E-1
7.889E-1
 2 201
26 C0259783 mixed gliomas DisGeNET BeFree 2.589E-3 3.193E-2
2.060E-1
9.192E-1
 1 7
27 C1841984 GLOMUVENOUS MALFORMATIONS DisGeNET Curated 2.589E-3 3.193E-2
2.060E-1
9.192E-1
 1 7
28 C0206622 Adenomyoma DisGeNET BeFree 2.589E-3 3.193E-2
2.060E-1
9.192E-1
 1 7
29 C0004238 Atrial Fibrillation DisGeNET Curated 2.947E-3 3.193E-2
2.060E-1
1.000E0
 2 232
30 C0279682 Bladder Adenocarcinoma DisGeNET BeFree 2.959E-3 3.193E-2
2.060E-1
1.000E0
 1 8
31 C0262428 Collagen-vascular disease DisGeNET BeFree 2.959E-3 3.193E-2
2.060E-1
1.000E0
 1 8
32 C1300347 Atypical polypoid adenomyoma DisGeNET BeFree 2.959E-3 3.193E-2
2.060E-1
1.000E0
 1 8
33 C0206736 Nevus, Blue DisGeNET BeFree 3.328E-3 3.193E-2
2.060E-1
1.000E0
 1 9
34 C0347129 Anal intraepithelial neoplasia DisGeNET BeFree 3.328E-3 3.193E-2
2.060E-1
1.000E0
 1 9
35 C0043037 Common wart DisGeNET BeFree 3.328E-3 3.193E-2
2.060E-1
1.000E0
 1 9
36 C0235522 Disorder of vein DisGeNET BeFree 3.328E-3 3.193E-2
2.060E-1
1.000E0
 1 9
37 C0334317 Cystadenofibroma DisGeNET BeFree 3.328E-3 3.193E-2
2.060E-1
1.000E0
 1 9
38 C0521720 Corneal fibrosis DisGeNET BeFree 3.697E-3 3.280E-2
2.116E-1
1.000E0
 1 10
39 C0341038 Jaw Keratocyst DisGeNET BeFree 3.697E-3 3.280E-2
2.116E-1
1.000E0
 1 10
40 C0496870 Benign neoplasm of liver DisGeNET BeFree 3.697E-3 3.280E-2
2.116E-1
1.000E0
 1 10
41 C0391861 Plasma cell inflammation DisGeNET BeFree 4.067E-3 3.280E-2
2.116E-1
1.000E0
 1 11
42 C0035021 Relapsing Fever DisGeNET BeFree 4.067E-3 3.280E-2
2.116E-1
1.000E0
 1 11
43 C0206720 Squamous Cell Neoplasms DisGeNET Curated 4.067E-3 3.280E-2
2.116E-1
1.000E0
 1 11
44 C3469605 PSEUDOHYPOALDOSTERONISM, TYPE IID DisGeNET Curated 4.067E-3 3.280E-2
2.116E-1
1.000E0
 1 11
45 C0004059 aspirin intolerance DisGeNET BeFree 4.436E-3 3.280E-2
2.116E-1
1.000E0
 1 12
46 C3665596 Warts DisGeNET Curated 4.804E-3 3.280E-2
2.116E-1
1.000E0
 1 13
47 C0751483 Familial Retinoblastoma DisGeNET Curated 4.804E-3 3.280E-2
2.116E-1
1.000E0
 1 13
48 C3160738 FANCONI ANEMIA, COMPLEMENTATION GROUP D2 DisGeNET Curated 4.804E-3 3.280E-2
2.116E-1
1.000E0
 1 13
49 C0742133 cervical cancer squamous cell DisGeNET BeFree 4.804E-3 3.280E-2
2.116E-1
1.000E0
 1 13
50 C0278620 refractory plasma cell neoplasm DisGeNET BeFree 4.804E-3 3.280E-2
2.116E-1
1.000E0
 1 13
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