Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc451_7, positive side

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1: GO: Molecular Function [Display Chart] 7 input genes in category / 38 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0003777 microtubule motor activity 3.482E-4 1.025E-2 4.334E-2 1.323E-2 2 77
2 GO:0003774 motor activity 1.019E-3 1.025E-2 4.334E-2 3.872E-2 2 132
3 GO:0051959 dynein light intermediate chain binding 1.874E-3 1.025E-2 4.334E-2
7.123E-2
1 5
4 GO:0043773 coenzyme F420-0 gamma-glutamyl ligase activity 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
5 GO:0043774 coenzyme F420-2 alpha-glutamyl ligase activity 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
6 GO:0070735 protein-glycine ligase activity 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
7 GO:0070738 tubulin-glycine ligase activity 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
8 GO:0008766 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
9 GO:0070737 protein-glycine ligase activity, elongating 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
10 GO:0018169 ribosomal S6-glutamic acid ligase activity 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
11 GO:0070736 protein-glycine ligase activity, initiating 3.369E-3 1.025E-2 4.334E-2
1.280E-1
2 242
12 GO:0070740 tubulin-glutamic acid ligase activity 3.452E-3 1.025E-2 4.334E-2
1.312E-1
2 245
13 GO:0070739 protein-glutamic acid ligase activity 3.507E-3 1.025E-2 4.334E-2
1.333E-1
2 247
14 GO:0016881 acid-amino acid ligase activity 3.791E-3 1.029E-2 4.350E-2
1.440E-1
2 257
15 GO:0016879 ligase activity, forming carbon-nitrogen bonds 4.898E-3 1.241E-2
5.246E-2
1.861E-1
2 293
16 GO:0071837 HMG box domain binding 8.597E-3 2.042E-2
8.633E-2
3.267E-1
1 23
17 GO:0016874 ligase activity 9.622E-3 2.151E-2
9.093E-2
3.656E-1
2 415
18 GO:0016887 ATPase activity 1.105E-2 2.333E-2
9.865E-2
4.200E-1
2 446
19 GO:0001102 RNA polymerase II activating transcription factor binding 1.417E-2 2.834E-2
1.198E-1
5.385E-1
1 38
20 GO:0019894 kinesin binding 1.565E-2 2.974E-2
1.257E-1
5.947E-1
1 42
21 GO:0033613 activating transcription factor binding 2.266E-2 4.101E-2
1.734E-1
8.612E-1
1 61
Show 16 more annotations

2: GO: Biological Process [Display Chart] 7 input genes in category / 185 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0021594 rhombomere formation 3.759E-4 1.396E-2
8.099E-2
6.954E-2
1 1
2 GO:0021664 rhombomere 5 morphogenesis 3.759E-4 1.396E-2
8.099E-2
6.954E-2
1 1
3 GO:0021666 rhombomere 5 formation 3.759E-4 1.396E-2
8.099E-2
6.954E-2
1 1
4 GO:0021660 rhombomere 3 formation 3.759E-4 1.396E-2
8.099E-2
6.954E-2
1 1
5 GO:0007422 peripheral nervous system development 3.774E-4 1.396E-2
8.099E-2
6.982E-2
2 80
6 GO:0021658 rhombomere 3 morphogenesis 7.516E-4 1.738E-2
1.008E-1
1.391E-1
1 2
7 GO:0042552 myelination 8.607E-4 1.738E-2
1.008E-1
1.592E-1
2 121
8 GO:0007272 ensheathment of neurons 8.892E-4 1.738E-2
1.008E-1
1.645E-1
2 123
9 GO:0008366 axon ensheathment 8.892E-4 1.738E-2
1.008E-1
1.645E-1
2 123
10 GO:0035284 brain segmentation 1.127E-3 1.738E-2
1.008E-1
2.085E-1
1 3
11 GO:0035283 central nervous system segmentation 1.127E-3 1.738E-2
1.008E-1
2.085E-1
1 3
12 GO:0021593 rhombomere morphogenesis 1.127E-3 1.738E-2
1.008E-1
2.085E-1
1 3
13 GO:0070086 ubiquitin-dependent endocytosis 1.503E-3 1.853E-2
1.075E-1
2.780E-1
1 4
14 GO:0021571 rhombomere 5 development 1.503E-3 1.853E-2
1.075E-1
2.780E-1
1 4
15 GO:0021569 rhombomere 3 development 1.503E-3 1.853E-2
1.075E-1
2.780E-1
1 4
16 GO:1904417 positive regulation of xenophagy 2.629E-3 2.702E-2
1.567E-1
4.863E-1
1 7
17 GO:1904415 regulation of xenophagy 2.629E-3 2.702E-2
1.567E-1
4.863E-1
1 7
18 GO:0048251 elastic fiber assembly 2.629E-3 2.702E-2
1.567E-1
4.863E-1
1 7
19 GO:0007018 microtubule-based movement 3.194E-3 2.727E-2
1.582E-1
5.908E-1
2 235
20 GO:0021546 rhombomere development 3.379E-3 2.727E-2
1.582E-1
6.250E-1
1 9
21 GO:2000786 positive regulation of autophagosome assembly 3.379E-3 2.727E-2
1.582E-1
6.250E-1
1 9
22 GO:0034063 stress granule assembly 3.753E-3 2.727E-2
1.582E-1
6.944E-1
1 10
23 GO:0045217 cell-cell junction maintenance 3.753E-3 2.727E-2
1.582E-1
6.944E-1
1 10
24 GO:0021612 facial nerve structural organization 3.753E-3 2.727E-2
1.582E-1
6.944E-1
1 10
25 GO:2000121 regulation of removal of superoxide radicals 4.128E-3 2.727E-2
1.582E-1
7.637E-1
1 11
26 GO:0032060 bleb assembly 4.128E-3 2.727E-2
1.582E-1
7.637E-1
1 11
27 GO:0021610 facial nerve morphogenesis 4.128E-3 2.727E-2
1.582E-1
7.637E-1
1 11
28 GO:0021561 facial nerve development 4.128E-3 2.727E-2
1.582E-1
7.637E-1
1 11
29 GO:0034331 cell junction maintenance 4.877E-3 2.910E-2
1.688E-1
9.022E-1
1 13
30 GO:0044090 positive regulation of vacuole organization 4.877E-3 2.910E-2
1.688E-1
9.022E-1
1 13
31 GO:0021604 cranial nerve structural organization 4.877E-3 2.910E-2
1.688E-1
9.022E-1
1 13
32 GO:0034643 establishment of mitochondrion localization, microtubule-mediated 5.625E-3 3.154E-2
1.829E-1
1.000E0
1 15
33 GO:0047497 mitochondrion transport along microtubule 5.625E-3 3.154E-2
1.829E-1
1.000E0
1 15
34 GO:0021783 preganglionic parasympathetic fiber development 6.373E-3 3.468E-2
2.011E-1
1.000E0
1 17
35 GO:0051654 establishment of mitochondrion localization 6.747E-3 3.566E-2
2.069E-1
1.000E0
1 18
36 GO:0048486 parasympathetic nervous system development 7.495E-3 3.649E-2
2.116E-1
1.000E0
1 20
37 GO:0033962 cytoplasmic mRNA processing body assembly 7.495E-3 3.649E-2
2.116E-1
1.000E0
1 20
38 GO:0032288 myelin assembly 7.495E-3 3.649E-2
2.116E-1
1.000E0
1 20
39 GO:0048532 anatomical structure arrangement 7.868E-3 3.732E-2
2.165E-1
1.000E0
1 21
40 GO:0019430 removal of superoxide radicals 8.988E-3 3.936E-2
2.283E-1
1.000E0
1 24
41 GO:0046755 viral budding 9.361E-3 3.936E-2
2.283E-1
1.000E0
1 25
42 GO:1902590 multi-organism organelle organization 9.361E-3 3.936E-2
2.283E-1
1.000E0
1 25
43 GO:0021602 cranial nerve morphogenesis 9.734E-3 3.936E-2
2.283E-1
1.000E0
1 26
44 GO:0090322 regulation of superoxide metabolic process 1.011E-2 3.936E-2
2.283E-1
1.000E0
1 27
45 GO:0071451 cellular response to superoxide 1.011E-2 3.936E-2
2.283E-1
1.000E0
1 27
46 GO:0008089 anterograde axonal transport 1.011E-2 3.936E-2
2.283E-1
1.000E0
1 27
47 GO:0071450 cellular response to oxygen radical 1.011E-2 3.936E-2
2.283E-1
1.000E0
1 27
48 GO:0085029 extracellular matrix assembly 1.048E-2 3.936E-2
2.283E-1
1.000E0
1 28
49 GO:0051656 establishment of organelle localization 1.072E-2 3.936E-2
2.283E-1
1.000E0
2 438
50 GO:0007274 neuromuscular synaptic transmission 1.085E-2 3.936E-2
2.283E-1
1.000E0
1 29
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 7 input genes in category / 22 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005875 microtubule associated complex 1.360E-3 1.615E-2
5.961E-2
2.993E-2 2 156
2 GO:0071953 elastic fiber 1.468E-3 1.615E-2
5.961E-2
3.230E-2 1 4
3 GO:0043209 myelin sheath 2.266E-3 1.662E-2
6.133E-2
4.985E-2 2 202
4 GO:0043218 compact myelin 6.958E-3 3.061E-2
1.130E-1
1.531E-1
1 19
5 GO:0005868 cytoplasmic dynein complex 6.958E-3 3.061E-2
1.130E-1
1.531E-1
1 19
6 GO:0005874 microtubule 9.715E-3 3.562E-2
1.315E-1
2.137E-1
2 426
7 GO:1904115 axon cytoplasm 1.315E-2 4.132E-2
1.525E-1
2.893E-1
1 36
8 GO:0030286 dynein complex 1.641E-2 4.513E-2
1.666E-1
3.611E-1
1 45
9 GO:0005871 kinesin complex 2.003E-2 4.896E-2
1.807E-1
4.406E-1
1 55
Show 4 more annotations

4: Human Phenotype [Display Chart] 7 input genes in category / 524 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0002936 Distal sensory impairment 1.179E-12 6.176E-10 4.224E-9 6.176E-10 7 96
2 HP:0008994 Proximal muscle weakness in lower limbs 1.190E-11 3.118E-9 2.133E-8 6.236E-9 6 54
3 HP:0002460 Distal muscle weakness 3.050E-11 5.327E-9 3.644E-8 1.598E-8 7 151
4 HP:0001761 Pes cavus 1.819E-10 2.383E-8 1.630E-7 9.531E-8 7 194
5 HP:0003474 Sensory impairment 2.884E-10 3.022E-8 2.067E-7 1.511E-7 7 207
6 HP:0001437 Abnormality of the musculature of the lower limbs 3.487E-10 3.046E-8 2.083E-7 1.827E-7 6 93
7 HP:0003376 Steppage gait 4.710E-10 3.526E-8 2.412E-7 2.468E-7 5 37
8 HP:0040129 Abnormal nerve conduction velocity 6.150E-10 3.581E-8 2.449E-7 3.223E-7 6 102
9 HP:0000762 Decreased nerve conduction velocity 6.150E-10 3.581E-8 2.449E-7 3.223E-7 6 102
10 HP:0003693 Distal amyotrophy 7.347E-10 3.626E-8 2.480E-7 3.850E-7 6 105
11 HP:0040131 Abnormal motor nerve conduction velocity 9.176E-10 3.626E-8 2.480E-7 4.808E-7 5 42
12 HP:0001765 Hammertoe 9.176E-10 3.626E-8 2.480E-7 4.808E-7 5 42
13 HP:0003431 Decreased motor nerve conduction velocity 9.176E-10 3.626E-8 2.480E-7 4.808E-7 5 42
14 HP:0003134 Abnormality of peripheral nerve conduction 1.032E-9 3.626E-8 2.480E-7 5.410E-7 6 111
15 HP:0009027 Foot dorsiflexor weakness 1.038E-9 3.626E-8 2.480E-7 5.439E-7 5 43
16 HP:0045010 Abnormality of peripheral nerves 1.282E-9 4.058E-8 2.775E-7 6.718E-7 6 115
17 HP:0001436 Abnormality of the foot musculature 1.316E-9 4.058E-8 2.775E-7 6.898E-7 5 45
18 HP:0001265 Hyporeflexia 3.303E-9 9.616E-8 6.577E-7 1.731E-6 7 292
19 HP:0000763 Sensory neuropathy 1.237E-8 3.412E-7 2.334E-6 6.483E-6 7 352
20 HP:0000764 Peripheral axonal degeneration 1.890E-8 4.952E-7 3.387E-6 9.903E-6 6 179
21 HP:0003690 Limb muscle weakness 3.271E-8 8.162E-7 5.583E-6 1.714E-5 6 196
22 HP:0003383 Onion bulb formation 3.465E-8 8.254E-7 5.645E-6 1.816E-5 4 28
23 HP:0001315 Reduced tendon reflexes 4.302E-8 9.645E-7 6.597E-6 2.254E-5 7 420
24 HP:0003701 Proximal muscle weakness 4.418E-8 9.645E-7 6.597E-6 2.315E-5 6 206
25 HP:0030177 Abnormality of peripheral nervous system electrophysiology 7.321E-8 1.534E-6 1.050E-5 3.836E-5 6 224
26 HP:0003382 Hypertrophic nerve changes 1.125E-7 2.235E-6 1.529E-5 5.894E-5 3 8
27 HP:0003202 Skeletal muscle atrophy 1.152E-7 2.235E-6 1.529E-5 6.036E-5 7 483
28 HP:0003380 Decreased number of peripheral myelinated nerve fibers 1.703E-7 3.186E-6 2.179E-5 8.922E-5 4 41
29 HP:0001178 Ulnar claw 2.407E-7 4.349E-6 2.975E-5 1.261E-4 3 10
30 HP:0003481 Segmental peripheral demyelination/remyelination 5.726E-7 9.679E-6 6.620E-5 3.000E-4 3 13
31 HP:0010871 Sensory ataxia 5.726E-7 9.679E-6 6.620E-5 3.000E-4 3 13
32 HP:0009127 Abnormality of the musculature of the limbs 6.119E-7 1.002E-5 6.854E-5 3.207E-4 6 319
33 HP:0011808 Decreased patellar reflex 1.896E-6 2.922E-5 1.999E-4 9.935E-4 2 2
34 HP:0007351 Upper limb postural tremor 1.896E-6 2.922E-5 1.999E-4 9.935E-4 2 2
35 HP:0001284 Areflexia 2.648E-6 3.965E-5 2.712E-4 1.388E-3 5 201
36 HP:0010831 Impaired proprioception 4.570E-6 6.472E-5 4.426E-4 2.395E-3 3 25
37 HP:0010870 Abnormality of proprioception 4.570E-6 6.472E-5 4.426E-4 2.395E-3 3 25
38 HP:0002922 Increased CSF protein 1.078E-5 1.449E-4 9.911E-4 5.651E-3 3 33
39 HP:0025456 Abnormal CSF protein level 1.078E-5 1.449E-4 9.911E-4 5.651E-3 3 33
40 HP:0003449 Cold-induced muscle cramps 1.136E-5 1.488E-4 1.018E-3 5.953E-3 2 4
41 HP:0004336 Myelin outfoldings 2.836E-5 3.538E-4 2.420E-3 1.486E-2 2 6
42 HP:0030173 Peripheral hypermyelination 2.836E-5 3.538E-4 2.420E-3 1.486E-2 2 6
43 HP:0003378 Axonal degeneration/regeneration 3.968E-5 4.835E-4 3.307E-3 2.079E-2 2 7
44 HP:0200085 Limb tremor 5.286E-5 6.287E-4 4.300E-3 2.770E-2 2 8
45 HP:0001171 Split hand 5.399E-5 6.287E-4 4.300E-3 2.829E-2 3 56
46 HP:0100257 Ectrodactyly 6.002E-5 6.837E-4 4.676E-3 3.145E-2 3 58
47 HP:0007182 Peripheral hypomyelination 6.792E-5 7.572E-4 5.179E-3 3.559E-2 2 9
48 HP:0003130 Abnormal peripheral myelination 8.017E-5 8.752E-4 5.986E-3 4.201E-2 4 189
49 HP:0002600 Hyporeflexia of lower limbs 2.253E-4 2.409E-3 1.648E-2
1.180E-1
2 16
50 HP:0003477 Peripheral axonal neuropathy 2.797E-4 2.931E-3 2.005E-2
1.466E-1
3 97
Show 45 more annotations

5: Mouse Phenotype [Display Chart] 7 input genes in category / 344 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0011906 increased Schwann cell proliferation 3.780E-9 6.502E-7 4.174E-6 1.300E-6 3 6
2 MP:0011905 abnormal Schwann cell proliferation 3.780E-9 6.502E-7 4.174E-6 1.300E-6 3 6
3 MP:0008814 decreased nerve conduction velocity 1.533E-8 1.758E-6 1.128E-5 5.273E-6 4 49
4 MP:0011904 abnormal Schwann cell physiology 4.151E-8 3.570E-6 2.292E-5 1.428E-5 3 12
5 MP:0005403 abnormal nerve conduction 8.740E-8 6.013E-6 3.860E-5 3.006E-5 4 75
6 MP:0000753 paralysis 1.763E-6 1.011E-4 6.487E-4 6.063E-4 4 158
7 MP:0001106 abnormal Schwann cell morphology 3.658E-6 1.590E-4 1.021E-3 1.258E-3 3 50
8 MP:0001105 abnormal PNS glial cell morphology 3.885E-6 1.590E-4 1.021E-3 1.337E-3 3 51
9 MP:0001405 impaired coordination 4.160E-6 1.590E-4 1.021E-3 1.431E-3 5 482
10 MP:0009538 abnormal synapse morphology 5.486E-6 1.887E-4 1.211E-3 1.887E-3 4 210
11 MP:0005404 abnormal axon morphology 7.346E-6 2.297E-4 1.475E-3 2.527E-3 4 226
12 MP:0003871 abnormal myelin sheath morphology 1.520E-5 4.357E-4 2.797E-3 5.229E-3 3 80
13 MP:0010742 increased Schwann cell number 1.758E-5 4.653E-4 2.987E-3 6.048E-3 2 10
14 MP:0000755 hindlimb paralysis 2.550E-5 6.018E-4 3.863E-3 8.771E-3 3 95
15 MP:0001053 abnormal neuromuscular synapse morphology 2.799E-5 6.018E-4 3.863E-3 9.629E-3 3 98
16 MP:0013147 limb paralysis 2.799E-5 6.018E-4 3.863E-3 9.629E-3 3 98
17 MP:0001051 abnormal somatic motor system morphology 3.250E-5 6.394E-4 4.104E-3 1.118E-2 3 103
18 MP:0000921 demyelination 3.346E-5 6.394E-4 4.104E-3 1.151E-2 3 104
19 MP:0002272 abnormal nervous system electrophysiology 4.577E-5 8.287E-4 5.320E-3 1.575E-2 4 359
20 MP:0003690 abnormal glial cell physiology 5.135E-5 8.685E-4 5.575E-3 1.767E-2 3 120
21 MP:0011731 decreased myelin sheath thickness 5.302E-5 8.685E-4 5.575E-3 1.824E-2 2 17
22 MP:0013438 dysmyelination 6.662E-5 1.042E-3 6.687E-3 2.292E-2 2 19
23 MP:0005112 abnormal spinal cord ventral horn morphology 7.400E-5 1.107E-3 7.105E-3 2.546E-2 2 20
24 MP:0003634 abnormal glial cell morphology 9.459E-5 1.356E-3 8.703E-3 3.254E-2 4 432
25 MP:0008415 abnormal neurite morphology 1.261E-4 1.735E-3 1.114E-2 4.338E-2 4 465
26 MP:0004768 abnormal axonal transport 1.364E-4 1.805E-3 1.158E-2 4.692E-2 2 27
27 MP:0000920 abnormal myelination 2.597E-4 3.309E-3 2.124E-2
8.934E-2
3 207
28 MP:0004263 abnormal limb posture 3.491E-4 4.289E-3 2.753E-2
1.201E-1
2 43
29 MP:0008503 abnormal spinal cord grey matter morphology 3.635E-4 4.312E-3 2.768E-2
1.251E-1
3 232
30 MP:0002651 abnormal sciatic nerve morphology 5.310E-4 6.089E-3 3.909E-2
1.827E-1
2 53
31 MP:0001513 limb grasping 5.555E-4 6.164E-3 3.957E-2
1.911E-1
3 268
32 MP:0001504 abnormal posture 6.382E-4 6.644E-3 4.265E-2
2.195E-1
3 281
33 MP:0012804 abnormal rhombomere 6 morphology 6.760E-4 6.644E-3 4.265E-2
2.325E-1
1 1
34 MP:0012795 absent rhombomere 3 6.760E-4 6.644E-3 4.265E-2
2.325E-1
1 1
35 MP:0012805 decreased rhombomere 6 size 6.760E-4 6.644E-3 4.265E-2
2.325E-1
1 1
36 MP:0011083 lethality at weaning, complete penetrance 8.231E-4 7.865E-3
5.049E-2
2.832E-1
2 66
37 MP:0000745 tremors 9.848E-4 9.156E-3
5.878E-2
3.388E-1
3 326
38 MP:0001524 impaired limb coordination 1.034E-3 9.359E-3
6.008E-2
3.556E-1
2 74
39 MP:0000955 abnormal spinal cord morphology 1.113E-3 9.817E-3
6.302E-2
3.829E-1
3 340
40 MP:0011994 increased nerve conduction velocity 1.352E-3 1.134E-2
7.280E-2
4.650E-1
1 2
41 MP:0012801 decreased rhombomere 5 size 1.352E-3 1.134E-2
7.280E-2
4.650E-1
1 2
42 MP:0000939 decreased motor neuron number 1.394E-3 1.141E-2
7.327E-2
4.794E-1
2 86
43 MP:0010053 decreased grip strength 1.434E-3 1.147E-2
7.364E-2
4.933E-1
3 371
44 MP:0000747 muscle weakness 1.733E-3 1.355E-2
8.697E-2
5.961E-1
2 96
45 MP:0005405 axon degeneration 1.842E-3 1.367E-2
8.776E-2
6.336E-1
2 99
46 MP:0012793 decreased rhombomere 3 size 2.027E-3 1.367E-2
8.776E-2
6.972E-1
1 3
47 MP:0008155 decreased diameter of radius 2.027E-3 1.367E-2
8.776E-2
6.972E-1
1 3
48 MP:0012803 absent rhombomere 5 2.027E-3 1.367E-2
8.776E-2
6.972E-1
1 3
49 MP:0011406 abnormal retrotrapezoid nucleus morphology 2.027E-3 1.367E-2
8.776E-2
6.972E-1
1 3
50 MP:0005113 decreased spinal cord ventral horn cell number 2.027E-3 1.367E-2
8.776E-2
6.972E-1
1 3
Show 45 more annotations

6: Domain [Display Chart] 7 input genes in category / 100 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PF10570 Myelin-PO C Pfam 3.736E-4 6.227E-3 3.230E-2 3.736E-2 1 1
2 IPR003936 PMP22 InterPro 3.736E-4 6.227E-3 3.230E-2 3.736E-2 1 1
3 IPR019566 Myelin-PO C InterPro 3.736E-4 6.227E-3 3.230E-2 3.736E-2 1 1
4 IPR029869 P0 InterPro 3.736E-4 6.227E-3 3.230E-2 3.736E-2 1 1
5 PS00568 MYELIN P0 PROSITE 3.736E-4 6.227E-3 3.230E-2 3.736E-2 1 1
6 IPR019738 Myelin P0 CS InterPro 3.736E-4 6.227E-3 3.230E-2 3.736E-2 1 1
7 IPR021849 DUF3446 InterPro 1.121E-3 1.401E-2
7.266E-2
1.121E-1
1 3
8 PF11928 DUF3446 Pfam 1.121E-3 1.401E-2
7.266E-2
1.121E-1
1 3
9 IPR022140 Kinesin-like KIF1-typ InterPro 1.494E-3 1.494E-2
7.749E-2
1.494E-1
1 4
10 PF12423 KIF1B Pfam 1.494E-3 1.494E-2
7.749E-2
1.494E-1
1 4
11 IPR032405 Kinesin assoc InterPro 2.240E-3 1.600E-2
8.300E-2
2.240E-1
1 6
12 PF12473 DUF3694 Pfam 2.240E-3 1.600E-2
8.300E-2
2.240E-1
1 6
13 IPR022164 Kinesin-like InterPro 2.240E-3 1.600E-2
8.300E-2
2.240E-1
1 6
14 PF16183 Kinesin assoc Pfam 2.240E-3 1.600E-2
8.300E-2
2.240E-1
1 6
15 IPR000920 Myelin P0-rel InterPro 2.986E-3 1.645E-2
8.532E-2
2.986E-1
1 8
16 PF08385 DHC N1 Pfam 2.986E-3 1.645E-2
8.532E-2
2.986E-1
1 8
17 IPR013594 Dynein heavy dom-1 InterPro 2.986E-3 1.645E-2
8.532E-2
2.986E-1
1 8
18 PS01222 PMP22 2 PROSITE 3.358E-3 1.645E-2
8.532E-2
3.358E-1
1 9
19 IPR004032 PMP22 EMP MP20 InterPro 3.358E-3 1.645E-2
8.532E-2
3.358E-1
1 9
20 PS01221 PMP22 1 PROSITE 3.358E-3 1.645E-2
8.532E-2
3.358E-1
1 9
21 IPR004825 Insulin InterPro 4.103E-3 1.645E-2
8.532E-2
4.103E-1
1 11
22 SM00078 IlGF SMART 4.103E-3 1.645E-2
8.532E-2
4.103E-1
1 11
23 IPR016179 Insulin-like InterPro 4.103E-3 1.645E-2
8.532E-2
4.103E-1
1 11
24 PF12780 AAA 8 Pfam 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
25 IPR024317 Dynein heavy chain D4 dom InterPro 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
26 IPR011704 ATPase dyneun-rel AAA InterPro 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
27 PF12777 MT Pfam 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
28 PF08393 DHC N2 Pfam 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
29 IPR024743 Dynein HC stalk InterPro 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
30 PF07728 AAA 5 Pfam 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
31 IPR013602 Dynein heavy dom-2 InterPro 5.220E-3 1.645E-2
8.532E-2
5.220E-1
1 14
32 IPR004273 Dynein heavy dom InterPro 5.592E-3 1.645E-2
8.532E-2
5.592E-1
1 15
33 IPR026983 DHC fam InterPro 5.592E-3 1.645E-2
8.532E-2
5.592E-1
1 15
34 PF03028 Dynein heavy Pfam 5.592E-3 1.645E-2
8.532E-2
5.592E-1
1 15
35 IPR026823 cEGF InterPro 9.676E-3 2.688E-2
1.394E-1
9.676E-1
1 26
36 PF12662 cEGF Pfam 9.676E-3 2.688E-2
1.394E-1
9.676E-1
1 26
37 SM00240 FHA SMART 1.042E-2 2.815E-2
1.460E-1
1.000E0
1 28
38 PS50006 FHA DOMAIN PROSITE 1.153E-2 2.956E-2
1.533E-1
1.000E0
1 31
39 PF00498 FHA Pfam 1.153E-2 2.956E-2
1.533E-1
1.000E0
1 31
40 IPR000253 FHA dom InterPro 1.338E-2 3.201E-2
1.661E-1
1.000E0
1 36
41 2.60.200.20 - Gene3D 1.338E-2 3.201E-2
1.661E-1
1.000E0
1 36
42 PF00822 PMP22 Claudin Pfam 1.485E-2 3.201E-2
1.661E-1
1.000E0
1 40
43 IPR019821 Kinesin motor CS InterPro 1.522E-2 3.201E-2
1.661E-1
1.000E0
1 41
44 PF07647 SAM 2 Pfam 1.596E-2 3.201E-2
1.661E-1
1.000E0
1 43
45 IPR027640 Kinesin-like fam InterPro 1.596E-2 3.201E-2
1.661E-1
1.000E0
1 43
46 3.40.850.10 - Gene3D 1.633E-2 3.201E-2
1.661E-1
1.000E0
1 44
47 SM00129 KISc SMART 1.633E-2 3.201E-2
1.661E-1
1.000E0
1 44
48 PF00225 Kinesin Pfam 1.633E-2 3.201E-2
1.661E-1
1.000E0
1 44
49 PS50067 KINESIN MOTOR 2 PROSITE 1.633E-2 3.201E-2
1.661E-1
1.000E0
1 44
50 IPR001752 Kinesin motor dom InterPro 1.633E-2 3.201E-2
1.661E-1
1.000E0
1 44
Show 45 more annotations

7: Pathway [Display Chart] 7 input genes in category / 47 annotations before applied cutoff / 12450 genes in category

No results to display

8: Pubmed [Display Chart] 7 input genes in category / 1503 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 20301532 Charcot-Marie-Tooth Hereditary Neuropathy Overview Pubmed 1.992E-17 2.993E-14 2.363E-13 2.993E-14 6 48
2 11835375 Charcot-Marie-Tooth disease and related neuropathies: mutation distribution and genotype-phenotype correlation. Pubmed 4.973E-14 3.737E-11 2.950E-10 7.475E-11 4 9
3 10638493 Experimental models of peripheral neuropathies. Pubmed 3.770E-12 1.574E-9 1.243E-8 5.666E-9 3 3
4 20301462 Charcot-Marie-Tooth Neuropathy Type 2 Pubmed 4.190E-12 1.574E-9 1.243E-8 6.298E-9 4 24
5 11545686 Screening for mutations in a genetically heterogeneous disorder: DHPLC versus DNA sequence for mutation detection in multiple genes causing Charcot-Marie-Tooth neuropathy. Pubmed 1.508E-11 4.532E-9 3.577E-8 2.266E-8 3 4
6 20301384 Charcot-Marie-Tooth Neuropathy Type 1 Pubmed 3.769E-11 9.442E-9 7.452E-8 5.665E-8 3 5
7 20427655 CNS/PNS boundary transgression by central glia in the absence of Schwann cells or Krox20/Egr2 function. Pubmed 2.110E-10 4.531E-8 3.576E-7 3.172E-7 3 8
8 19244508 Congenital hypomyelinating neuropathy with lethal conduction failure in mice carrying the Egr2 I268N mutation. Pubmed 8.287E-10 1.557E-7 1.229E-6 1.246E-6 3 12
9 19805360 The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development. Pubmed 2.109E-9 3.522E-7 2.780E-6 3.170E-6 3 16
10 12211648 Mutation analysis of the MPZ and PMP22 genes in Croatian patients. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
11 7762451 Molecular genetics of Charcot-Marie-Tooth neuropathy. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
12 10797391 Neuromyotonia in mice with hereditary myelinopathies. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
13 1384766 P0 protein in normal, trembler heterozygous/homozygous mice during active PNS myelination. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
14 19487693 Induction of myelin protein zero by early growth response 2 through upstream and intragenic elements. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
15 15050444 Myelin protein zero gene mutations in Taiwanese patients with Charcot-Marie-Tooth disease type 1. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
16 10559784 Localization and functional roles of PMP22 in peripheral nerves of P0-deficient mice. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
17 16373334 Direct regulation of myelin protein zero expression by the Egr2 transactivator. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
18 10212299 Peripheral myelin protein 22 and protein zero: a novel association in peripheral nervous system myelin. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
19 7518101 Charcot-Marie-Tooth disease: a new paradigm for the mechanism of inherited disease. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
20 15555916 Peripheral myelin protein 22 kDa and protein zero: domain specific trans-interactions. Pubmed 2.879E-8 2.164E-6 1.708E-5 4.328E-5 2 2
21 16912585 Mutation frequency for Charcot-Marie-Tooth disease type 1 in the Chinese population is similar to that in the global ethnic patients. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
22 11438991 Charcot-Marie-Tooth disease type I and related demyelinating neuropathies: Mutation analysis in a large cohort of Italian families. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
23 21411665 Regulation of the PMP22 gene through an intronic enhancer. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
24 9633821 Spectrum of mutations in Finnish patients with Charcot-Marie-Tooth disease and related neuropathies. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
25 9187667 Mutational analysis of the MPZ, PMP22 and Cx32 genes in patients of Spanish ancestry with Charcot-Marie-Tooth disease and hereditary neuropathy with liability to pressure palsies. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
26 10737979 Screening for mutations in the peripheral myelin genes PMP22, MPZ and Cx32 (GJB1) in Russian Charcot-Marie-Tooth neuropathy patients. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
27 9418989 Animal models for inherited peripheral neuropathies. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
28 12402337 Molecular analysis in Japanese patients with Charcot-Marie-Tooth disease: DGGE analysis for PMP22, MPZ, and Cx32/GJB1 mutations. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
29 22243284 Mutational analysis of PMP22, GJB1 and MPZ in Greek Charcot-Marie-Tooth type 1 neuropathy patients. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
30 20071523 Conduction block in PMP22 deficiency. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
31 10586256 Nerve conduction abnormalities and neuromyotonia in genetically engineered mouse models of human hereditary neuropathies. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
32 12497641 Novel mutations in the Charcot-Marie-Tooth disease genes PMP22, MPZ, and GJB1. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
33 20731761 Bex1 is involved in the regeneration of axons after injury. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
34 9888385 Mutations in the peripheral myelin genes and associated genes in inherited peripheral neuropathies. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
35 23743332 Charcot-Marie-Tooth disease: frequency of genetic subtypes in a German neuromuscular center population. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
36 7581438 Myelin genes: getting the dosage right. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
37 19259128 Identification and in silico analysis of 14 novel GJB1, MPZ and PMP22 gene mutations. Pubmed 8.637E-8 3.509E-6 2.769E-5 1.298E-4 2 3
38 22765307 Mutational analysis of PMP22, EGR2, LITAF and NEFL in Greek Charcot-Marie-Tooth type 1 patients. Pubmed 1.727E-7 6.038E-6 4.765E-5 2.596E-4 2 4
39 15241803 Mutational analysis of PMP22, MPZ, GJB1, EGR2 and NEFL in Korean Charcot-Marie-Tooth neuropathy patients. Pubmed 1.727E-7 6.038E-6 4.765E-5 2.596E-4 2 4
40 7807578 Neurological mouse mutants and the genes of myelin. Pubmed 1.727E-7 6.038E-6 4.765E-5 2.596E-4 2 4
41 24819634 Mutation analysis of MFN2, GJB1, MPZ and PMP22 in Italian patients with axonal Charcot-Marie-Tooth disease. Pubmed 1.727E-7 6.038E-6 4.765E-5 2.596E-4 2 4
42 21824506 Age-related changes in myelin morphology, electrophysiological property and myelin-associated protein expression of mouse sciatic nerves. Pubmed 1.727E-7 6.038E-6 4.765E-5 2.596E-4 2 4
43 7935840 Krox-20 controls myelination in the peripheral nervous system. Pubmed 1.727E-7 6.038E-6 4.765E-5 2.596E-4 2 4
44 8662541 The POU factor Oct-6 and Schwann cell differentiation. Pubmed 2.879E-7 9.205E-6 7.266E-5 4.327E-4 2 5
45 7568894 The molecular basis of the neuropathies of mouse and human. Pubmed 2.879E-7 9.205E-6 7.266E-5 4.327E-4 2 5
46 15713637 The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination. Pubmed 2.879E-7 9.205E-6 7.266E-5 4.327E-4 2 5
47 15312649 The protooncogene Ski controls Schwann cell proliferation and myelination. Pubmed 2.879E-7 9.205E-6 7.266E-5 4.327E-4 2 5
48 9338783 Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Pubmed 4.318E-7 1.298E-5 1.024E-4 6.489E-4 2 6
49 23012656 Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. Pubmed 4.318E-7 1.298E-5 1.024E-4 6.489E-4 2 6
50 20220021 Adam22 is a major neuronal receptor for Lgi4-mediated Schwann cell signaling. Pubmed 4.318E-7 1.298E-5 1.024E-4 6.489E-4 2 6
Show 45 more annotations

9: Interaction [Display Chart] 7 input genes in category / 328 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:MPZ MPZ interactions 1.339E-6 4.393E-4 2.799E-3 4.393E-4 2 5
2 int:PMP22 PMP22 interactions 1.043E-5 1.711E-3 1.090E-2 3.422E-3 2 13
3 int:NINL NINL interactions 6.301E-5 6.889E-3 4.389E-2 2.067E-2 3 219
4 int:MAGEA1 MAGEA1 interactions 4.384E-4 3.595E-2
2.291E-1
1.438E-1
2 82

10: Cytoband [Display Chart] 7 input genes in category / 7 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 14q32.1 14q32.1 2.220E-3 9.179E-3 2.380E-2 1.554E-2 1 11
2 1p36.2 1p36.2 2.623E-3 9.179E-3 2.380E-2 1.836E-2 1 13
3 10q21.1 10q21.1 4.234E-3 9.879E-3 2.561E-2 2.964E-2 1 21
4 9q33.3 9q33.3 7.449E-3 1.196E-2 3.102E-2
5.214E-2
1 37
5 1q23.3 1q23.3 1.026E-2 1.196E-2 3.102E-2
7.179E-2
1 51
6 17p12 17p12 1.026E-2 1.196E-2 3.102E-2
7.179E-2
1 51
7 14q32 14q32 1.206E-2 1.206E-2 3.126E-2
8.439E-2
1 60
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 6 input genes in category / 113 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$TEF1 Q6 V$TEF1 Q6 1.181E-4 1.334E-2
7.084E-2
1.334E-2 3 180

12: Gene Family [Display Chart] 6 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 556 Fibulins genenames.org 2.636E-3 1.284E-2 3.146E-2 1.581E-2 1 8
2 538 WD repeat domain containing|Dyneins, cytoplasmic genenames.org 4.280E-3 1.284E-2 3.146E-2 2.568E-2 1 13
3 622 Kinesins|Protein phosphatase 1 regulatory subunits genenames.org 1.508E-2 3.015E-2
7.387E-2
9.046E-2
1 46
4 760 Fibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors genenames.org 2.868E-2 4.301E-2
1.054E-1
1.721E-1
1 88

13: Coexpression [Display Chart] 7 input genes in category / 918 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M1047 Genes specifically expressed in samples from patients with pediatric acute myeloid leukemia (AML) bearing inv(16) translocation. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.983E-4 3.166E-2
2.343E-1
1.820E-1
3 421
2 M19636 Genes down-regulated during pubertal mammary gland development between week 6 and 7. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.391E-4 3.166E-2
2.343E-1
2.195E-1
2 79
3 20713713-TableS1b Human Breast Taube10 91genes EMTsignature up GeneSigDB 2.703E-4 3.166E-2
2.343E-1
2.481E-1
2 84
4 17148579-TableS1 Human Leukemia Bomben07 122genes GeneSigDB 3.034E-4 3.166E-2
2.343E-1
2.785E-1
2 89
5 17660535-TableS7 Mouse InnerEar Sajan08 109genes GeneSigDB 3.603E-4 3.166E-2
2.343E-1
3.308E-1
2 97
6 M15148 Genes down-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.465E-4 3.166E-2
2.343E-1
4.099E-1
2 108
7 M5942 Genes down-regulated in response to ultraviolet (UV) radiation. MSigDB H: Hallmark Gene Sets (v6.0) 7.915E-4 3.166E-2
2.343E-1
7.266E-1
2 144
8 15785748-Table3 Human Uterine Santin05 178genes GeneSigDB 8.697E-4 3.166E-2
2.343E-1
7.984E-1
2 151
9 M11011 Genes down-regulated in the temporal cortex samples from patients with major depressive disorder. MSigDB C2: CGP Curated Gene Sets (v6.0) 9.635E-4 3.166E-2
2.343E-1
8.845E-1
2 159
10 M2395 Genes up-regulated in pancreatic islets upon knockout of HNF1A [GeneID=6927]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.012E-3 3.166E-2
2.343E-1
9.291E-1
2 163
11 M8926 Genes down-regulated in CD4 [GeneID=920] T cells: naïve versus Th1. MSigDB C7: Immunologic Signatures (v6.0) 1.024E-3 3.166E-2
2.343E-1
9.405E-1
2 164
12 M8689 Top 200 marker genes down-regulated in the 'CTNNB1' subclass of hepatocellular carcinoma (HCC); characterized by activated CTNNB1 [GeneID=1499]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.100E-3 3.166E-2
2.343E-1
1.000E0
2 170
13 M7625 Genes up-regulated in memory CD8 T cells: 1' versus 4'. MSigDB C7: Immunologic Signatures (v6.0) 1.152E-3 3.166E-2
2.343E-1
1.000E0
2 174
14 M2827 Genes up-regulated in Sez-4 cells (T lymphocyte) that were first starved of IL2 [Gene ID=3558] and then stimulated with IL21 [Gene ID=59067]. MSigDB C6: Oncogenic Signatures (v6.0) 1.343E-3 3.166E-2
2.343E-1
1.000E0
2 188
15 M9590 Genes down-regulated in thymic T reg: CD24 int [GeneID=100133941] versus CD24 low [GeneID=100133941]. MSigDB C7: Immunologic Signatures (v6.0) 1.488E-3 3.166E-2
2.343E-1
1.000E0
2 198
16 M9641 Genes down-regulated in CD4 [GeneID=920] T helper cells (4h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 3.166E-2
2.343E-1
1.000E0
2 199
17 M5513 Genes up-regulated in comparison of macrophages versus Th2 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 3.166E-2
2.343E-1
1.000E0
2 199
18 M5510 Genes up-regulated in comparison of macrophages versus Th1 cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 3.166E-2
2.343E-1
1.000E0
2 199
19 M8076 Genes down-regulated in thymic implants from fetal liver versus those from fetal bone marrow. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 3.166E-2
2.343E-1
1.000E0
2 199
20 M8774 Genes down-regulated in dendritic cells: control versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 3.166E-2
2.343E-1
1.000E0
2 199
21 M10091 Genes down-regulated in mucinous ovarian carcinoma tumors of low malignant potential (LMP) compared to normal ovarian surface epithelium tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.502E-3 3.166E-2
2.343E-1
1.000E0
2 199
22 M1740 FOXP3 [GeneID=50943] target genes down-regulated in T lymphocytes after stimulation with IL2 [GeneID=3558]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.512E-3 3.166E-2
2.343E-1
1.000E0
1 5
23 M9751 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: follicular helper (Tfh) versus Ly6c low CXCR5- [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
24 M5893 Genes important for mitotic spindle assembly. MSigDB H: Hallmark Gene Sets (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
25 M5273 Genes up-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus macrophages treated with IL25 [GeneID=64806]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
26 M6629 Genes up-regulated in bone marrow-derived macrophages with IL10 [GeneID=3486] knockout and 45 min of stimulation by: LPS versus LPS and IL10 [GeneID=3486]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
27 M7902 Genes up-regulated in monocytes (12h) versus macrophages (12h) treated with IFNG, TNF [GeneID=3458;7124] and rosiglitazone [PubChem=77999]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
28 M5146 Genes down-regulated in untreated dendritic cells (DC) versus DCs exposed to parasite L. major. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
29 M6193 Genes down-regulated in polymorphonuclear leukocytes (24h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
30 M9738 Genes down-regulated in CD4 [GeneID=920] SMARTA T cells: naïve versus memory follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
31 M8197 Genes down-regulated in dobule positive thymocytefrom OT-2 transgenic mice injected with agonist peptide: wildtype versus expressing deltaP form of HDAC7 [GeneID=51564]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
32 M7437 Genes up-regulated in CD4 [GeneID=920] T cells: TGF beta versus IL6 [GeneID=3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
33 M9734 Genes up-regulated in CD4 [GeneID=920] SMARTA memory T cells: Th1 versus follicular helper (Tfh). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
34 M5930 Genes defining epithelial-mesenchymal transition, as in wound healing, fibrosis and metastasis. MSigDB H: Hallmark Gene Sets (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
35 M9338 Genes up-regulated in follicular B cells versus day 7 memory B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
36 M9742 Genes up-regulated in Th1 CD4 [GeneID=920] SMARTA T cells: effector during acute infection of LCMV versus memory. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
37 M3962 Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 1 h versus DC cells stimulated with Gardiquimod (TLR7 agonist) at 1 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
38 M6127 Genes down-regulated in CD4 [GeneID=920] T cells activated by anti-CD3 and anti-CD28: IL-12 (2h) versus untreated (2h). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
39 M6357 Genes up-regulated in Vd1 gamma delta T cells: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
40 M9629 Genes up-regulated in CD4 [GeneID=920] T helper cells (42h): Th0 versus TGFB1 and IL6 [GeneID=7040;3569]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
41 M9755 Genes down-regulated in CD4 [GeneID=920] SMARTA effector T cells during acute infection of LCMV: Ly6c int CXCR5+ [GeneID=643] versus Ly6c low CXCR5- [GeneID=643]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
42 M3435 Genes down-regulated in comparison of CD4 [GeneID=920] CD8 thymocytes stimulated with anti-Valpha2 antibodies versus CD4 [GeneID=920] CD8 thymocytes stimulated with anti-beta5 antibodies. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
43 M4624 Genes down-regulated in comparison of untreated CD25+ T effector cells at day 7 versus untreated CD25- T cells at day 7. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
44 M9622 Genes up-regulated in peripheral blood monocytes (PBMC): control versus IL10 [GeneID=3586]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 3.166E-2
2.343E-1
1.000E0
2 200
45 M13273 Genes down-regulated in papillary thyroid carcinoma (PTC) compared to normal tissue. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.034E-3 3.959E-2
2.930E-1
1.000E0
2 232
46 M1528 Genes up-regulated by in C3H/10T1/2 cells (embryonic pluripotent cell) in response to SSH [GeneID=6469]. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.116E-3 3.959E-2
2.930E-1
1.000E0
1 7
47 16501597-Table2 Mouse Viral Geserick06 8genes GeneSigDB 2.116E-3 3.959E-2
2.930E-1
1.000E0
1 7
48 M6161 Genes down-regulated by RUNX1-RUNX1T1 [GeneID=861;862] fusion protein in normal hematopoietic progenitors; their expression was sustained in subsequently developing granulocytes. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.116E-3 3.959E-2
2.930E-1
1.000E0
1 7
49 M1927 Genes down-regulated in partially reprogrammed and pluripotent cell populations (induced, iPS; and embryonic stem cells, ES) compared to parental lineage-commited cell lines. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.116E-3 3.959E-2
2.930E-1
1.000E0
1 7
50 M4716 Genes up-regulated in SH-SY5Y cells (neuroblastoma) after treatment with epoxomicin [PubChem=3035402], a protease inhibitor causing apoptosis. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.156E-3 3.959E-2
2.930E-1
1.000E0
2 239
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 7 input genes in category / 825 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup9/Adora2a/Adora2a,Fos BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/inhibitory/subGroup9/Adora2a/Adora2a,Fos BrainMap 1.048E-5 6.480E-3 4.726E-2 8.644E-3 3 148
2 BrainMap BrainAtlas - Human / Mouse Linnarsson Satellite glia Satellite glia Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Satellite glia Satellite glia Overall Top 200 Genes BrainMap 2.356E-5 6.480E-3 4.726E-2 1.944E-2 3 194
3 BrainMap BrainAtlas - Human / Mouse Linnarsson Satellite glia Satellite glia Top 200 BrainMap BrainAtlas - Human / Mouse Linnarsson Satellite glia Satellite glia Top 200 BrainMap 2.356E-5 6.480E-3 4.726E-2 1.944E-2 3 194
4 gudmap developingLowerUrinaryTract e13.5 bladder mesenchyme 500 DevelopingLowerUrinaryTract e13.5 bladder mesenchyme emap-3087 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 2.353E-4 3.361E-2
2.451E-1
1.941E-1
3 421
5 BM Top 100 - trigeminal ganglia BM Top 100 - trigeminal ganglia Body Map 2.550E-4 3.361E-2
2.451E-1
2.104E-1
2 77
6 GSM777050 100 Stromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5 Immgen.org, GSE15907 3.255E-4 3.361E-2
2.451E-1
2.685E-1
2 87
7 GSM777046 100 Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4 Immgen.org, GSE15907 4.045E-4 3.361E-2
2.451E-1
3.337E-1
2 97
8 Facebase RNAseq ratio e9.5 MandibularArch vs MaxillaryArch 1000 K4 FacebaseRNAseq ratio e9.5 MandibularArch vs MaxillaryArch top-relative-expression-ranked 1000 k-means-cluster#4 FaceBase_RNAseq 5.978E-4 3.361E-2
2.451E-1
4.932E-1
2 118
9 gudmap dev lower uro neuro e15.5 PelvicGanglion Sox10 k2 500 dev lower uro neuro e15.5 PelvicGanglion Sox10 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 6.919E-4 3.361E-2
2.451E-1
5.708E-1
2 127
10 Sample Type by Project: Shred 1/TCGA-Uvea/Uveal Melanoma/Epithelioid Cell/2/4 Sample Type by Project: Shred 1/TCGA-Uvea/Uveal Melanoma/Epithelioid Cell/2/4 TCGA-Uvea 7.028E-4 3.361E-2
2.451E-1
5.798E-1
2 128
11 Sample Type by Project: Shred 1/TCGA-Bladder/Urothelial Carcinoma/Non-Papillary Muscle Invasive Urothelial Carcinoma/5/0 Sample Type by Project: Shred 1/TCGA-Bladder/Urothelial Carcinoma/Non-Papillary Muscle Invasive Urothelial Carcinoma/5/0 TCGA-Bladder 8.279E-4 3.361E-2
2.451E-1
6.830E-1
2 139
12 Sample Type by Project: Shred 1/TCGA-Mesothelium/Mesothelioma /Diffuse Malignant/1/1 Sample Type by Project: Shred 1/TCGA-Mesothelium/Mesothelioma /Diffuse Malignant/1/1 TCGA-Mesothelium 8.637E-4 3.361E-2
2.451E-1
7.126E-1
2 142
13 Sample Type by Project: Shred 1/TCGA-Liver/Hepatocellular Carcinoma/Hepatocellular Carcinoma/4 Sample Type by Project: Shred 1/TCGA-Liver/Hepatocellular Carcinoma/Hepatocellular Carcinoma/4 TCGA-Liver 9.758E-4 3.361E-2
2.451E-1
8.050E-1
2 151
14 gudmap developingLowerUrinaryTract e13.5 bladder epithelial cells 1000 k3 DevelopingLowerUrinaryTract e13.5 bladder epithelial cells emap-30875 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.054E-3 3.361E-2
2.451E-1
8.697E-1
2 157
15 gudmap dev lower uro neuro e14.5 PelvicGanglion Sox10 k4 500 dev lower uro neuro e14.5 PelvicGanglion Sox10 k-means-cluster#4 top-relative-expression-ranked 500 Gudmap Mouse ST 1.0 1.054E-3 3.361E-2
2.451E-1
8.697E-1
2 157
16 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal fetal kidney Renal cell carcinoma/Kidney Normal fetal kidney T6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Renal cell carcinoma/Kidney Normal fetal kidney Renal cell carcinoma/Kidney Normal fetal kidney T6 Adult, Development, and Cancer types 1.068E-3 3.361E-2
2.451E-1
8.807E-1
2 158
17 gudmap developingLowerUrinaryTract e13.5 bladder mesenchyme 1000 k3 DevelopingLowerUrinaryTract e13.5 bladder mesenchyme emap-3087 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.081E-3 3.361E-2
2.451E-1
8.918E-1
2 159
18 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U-U/Kidney Normal fetal kidney U-U/Kidney Normal fetal kidney U6 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney U-U/Kidney Normal fetal kidney U-U/Kidney Normal fetal kidney U6 Adult, Development, and Cancer types 1.122E-3 3.361E-2
2.451E-1
9.254E-1
2 162
19 BrainMap BrainAtlas - Human / Mouse Linnarsson Enteric glia Enteric glia Top 200 BrainMap BrainAtlas - Human / Mouse Linnarsson Enteric glia Enteric glia Top 200 BrainMap 1.191E-3 3.361E-2
2.451E-1
9.829E-1
2 167
20 BrainMap BrainAtlas - Human / Mouse Linnarsson Enteric glia Enteric glia Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Enteric glia Enteric glia Overall Top 200 Genes BrainMap 1.191E-3 3.361E-2
2.451E-1
9.829E-1
2 167
21 Sample Type by Project: Shred 1/TCGA-Peripheral Nervous System/Paraganglioma/Paraganglioma/3/0 Sample Type by Project: Shred 1/TCGA-Peripheral Nervous System/Paraganglioma/Paraganglioma/3/0 TCGA-Peripheral Nervous System 1.206E-3 3.361E-2
2.451E-1
9.946E-1
2 168
22 gudmap developingKidney e11.5 ureteric bud 100 k2 DevelopingKidney e11.5 ureteric bud emap-3844 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.282E-3 3.361E-2
2.451E-1
1.000E0
1 4
23 Sample Type by Project: Shred 1/TCGA-Uvea/Uveal Melanoma/Spindle Cell/3/3 Sample Type by Project: Shred 1/TCGA-Uvea/Uveal Melanoma/Spindle Cell/3/3 TCGA-Uvea 1.367E-3 3.361E-2
2.451E-1
1.000E0
2 179
24 Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Overall Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Overall Top 200 Genes 1.367E-3 3.361E-2
2.451E-1
1.000E0
2 179
25 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Heart Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Heart Tabula Muris Consortium 1.490E-3 3.361E-2
2.451E-1
1.000E0
2 187
26 Sample Type by Project: Shred 1/TCGA-Breast/Breast Carcinoma/Ductal and Metaplastic Carcinoma/5/4 Sample Type by Project: Shred 1/TCGA-Breast/Breast Carcinoma/Ductal and Metaplastic Carcinoma/5/4 TCGA-Breast 1.506E-3 3.361E-2
2.451E-1
1.000E0
2 188
27 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Mammary Gland/stromal cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Mammary Gland/stromal cell Tabula Muris Consortium 1.506E-3 3.361E-2
2.451E-1
1.000E0
2 188
28 Cap mesenchyme (CM)/Cap mesenchyme (CM) a Cap mesenchyme (CM)/Cap mesenchyme (CM) a 1.522E-3 3.361E-2
2.451E-1
1.000E0
2 189
29 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Limb Muscle/mesenchymal stem cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Limb Muscle/mesenchymal stem cell Tabula Muris Consortium 1.538E-3 3.361E-2
2.451E-1
1.000E0
2 190
30 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Fat/mesenchymal stem cell of adipose Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Fat/mesenchymal stem cell of adipose Tabula Muris Consortium 1.538E-3 3.361E-2
2.451E-1
1.000E0
2 190
31 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Diaphrag/mesenchymal stem cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Diaphrag/mesenchymal stem cell Tabula Muris Consortium 1.554E-3 3.361E-2
2.451E-1
1.000E0
2 191
32 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Bladder/bladder cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Bladder/bladder cell Tabula Muris Consortium 1.570E-3 3.361E-2
2.451E-1
1.000E0
2 192
33 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Heart/fibroblast Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Heart/fibroblast Tabula Muris Consortium 1.570E-3 3.361E-2
2.451E-1
1.000E0
2 192
34 BrainMap BrainAtlas - Human / Mouse Linnarsson Oligodendrocyte Oligodendrocyte Overall Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Oligodendrocyte Oligodendrocyte Overall Top 200 Genes BrainMap 1.586E-3 3.361E-2
2.451E-1
1.000E0
2 193
35 BrainMap BrainAtlas - Human / Mouse Linnarsson Oligodendrocyte Oligodendrocyte Top 200 BrainMap BrainAtlas - Human / Mouse Linnarsson Oligodendrocyte Oligodendrocyte Top 200 BrainMap 1.586E-3 3.361E-2
2.451E-1
1.000E0
2 193
36 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/stromal cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Lung/stromal cell Tabula Muris Consortium 1.586E-3 3.361E-2
2.451E-1
1.000E0
2 193
37 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Aorta/fibroblast Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Aorta/fibroblast Tabula Muris Consortium 1.586E-3 3.361E-2
2.451E-1
1.000E0
2 193
38 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal fetal kidney Endothelium/Kidney Normal fetal kidney T2 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney Endothelium/Kidney Normal fetal kidney Endothelium/Kidney Normal fetal kidney T2 Adult, Development, and Cancer types 1.602E-3 3.361E-2
2.451E-1
1.000E0
1 5
39 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Trachea/mesenchymal cell Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Trachea/mesenchymal cell Tabula Muris Consortium 1.619E-3 3.361E-2
2.451E-1
1.000E0
2 195
40 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter U U/Ureter Normal RCC U U/Ureter Normal RCC U21 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Ureter U U/Ureter Normal RCC U U/Ureter Normal RCC U21 Adult, Development, and Cancer types 1.668E-3 3.361E-2
2.451E-1
1.000E0
2 198
41 Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma1-C6-KC2 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma1-C6-KC2 Top 200 Genes 1.719E-3 3.361E-2
2.451E-1
1.000E0
2 201
42 Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma2-C2-KC2 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma2-C2-KC2 Top 200 Genes 1.753E-3 3.361E-2
2.451E-1
1.000E0
2 203
43 Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma3-C4-KC4 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 P0 Stroma Stroma Subtype P0-Six2TGC Tsc1-Stroma3-C4-KC4 Top 200 Genes 1.753E-3 3.361E-2
2.451E-1
1.000E0
2 203
44 JC fibro 500 K3 JC fibro top-relative-expression-ranked 500 k-means-cluster#3 PCBC 1.804E-3 3.361E-2
2.451E-1
1.000E0
2 206
45 Kidney10XCellRanger Six2TGC TSC1 E14 Stroma Stroma Subtype E14-Six2TGC Tsc1-Stroma1-C2-KC3 Top 200 Genes Kidney10XCellRanger Six2TGC TSC1 E14 Stroma Stroma Subtype E14-Six2TGC Tsc1-Stroma1-C2-KC3 Top 200 Genes 1.856E-3 3.361E-2
2.451E-1
1.000E0
2 209
46 Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype MyoFB-3 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype MyoFB-3 Top 200 Genes 1.874E-3 3.361E-2
2.451E-1
1.000E0
2 210
47 Sample Type by Project: Shred 1/TCGA-Head and Neck/Head and Neck Carcinoma/Squamous Cell Carcinoma/4/3 Sample Type by Project: Shred 1/TCGA-Head and Neck/Head and Neck Carcinoma/Squamous Cell Carcinoma/4/3 TCGA-Head and Neck 1.923E-3 3.375E-2
2.461E-1
1.000E0
1 6
48 Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype MyoFB-3 PND07-28 Top 200 Genes Lungmap Lungmap - Mouse FluidigmC1 Fibroblast Fibroblast Subtype MyoFB-3 PND07-28 Top 200 Genes 1.999E-3 3.436E-2
2.506E-1
1.000E0
2 217
49 Kidney10XCellRanger Six2TGC E14 Stroma Stroma Subtype E14-Six2TGC-Stroma1-C8-KC4 Top 200 Genes Kidney10XCellRanger Six2TGC E14 Stroma Stroma Subtype E14-Six2TGC-Stroma1-C8-KC4 Top 200 Genes 2.185E-3 3.678E-2
2.682E-1
1.000E0
2 227
50 gudmap developingLowerUrinaryTract e13.5 bladder neck-urethr mesench 100 k4 DevelopingLowerUrinaryTract e13.5 bladder neck-urethr mesench emap-3087 k-means-cluster#4 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 2.243E-3 3.701E-2
2.699E-1
1.000E0
1 7
Show 45 more annotations

15: Computational [Display Chart] 6 input genes in category / 30 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M18257 GCM BMPR2 Neighborhood of BMPR2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.016E-3 2.556E-2
1.021E-1
3.047E-2 2 84
2 M15207 GCM CALM1 Neighborhood of CALM1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.704E-3 2.556E-2
1.021E-1
5.111E-2
2 109
3 M10191 GCM MAP4K4 Neighborhood of MAP4K4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.138E-3 4.138E-2
1.653E-1
1.241E-1
2 171

16: MicroRNA [Display Chart] 7 input genes in category / 284 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-768-5p:PITA hsa-miR-768-5p:PITA TOP PITA 6.708E-5 9.670E-3
6.023E-2
1.905E-2 2 130
2 hsa-miR-616:PITA hsa-miR-616:PITA TOP PITA 7.343E-5 9.670E-3
6.023E-2
2.085E-2 2 136
3 CTTGTAT,MIR-381:MSigDB CTTGTAT,MIR-381:MSigDB MSigDB 1.463E-4 9.670E-3
6.023E-2
4.154E-2 2 192
4 hsa-miR-485-5p:PITA hsa-miR-485-5p:PITA TOP PITA 1.493E-4 9.670E-3
6.023E-2
4.241E-2 2 194
5 hsa-miR-202:PITA hsa-miR-202:PITA TOP PITA 1.954E-4 9.670E-3
6.023E-2
5.550E-2
2 222
6 hsa-miR-451:mirSVR highEffct hsa-miR-451:mirSVR conserved highEffect-0.5 MicroRNA.org 2.043E-4 9.670E-3
6.023E-2
5.802E-2
2 227
7 ATGTACA,MIR-493:MSigDB ATGTACA,MIR-493:MSigDB MSigDB 3.420E-4 1.116E-2
6.950E-2
9.713E-2
2 294
8 hsa-miR-4755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.443E-4 1.116E-2
6.950E-2
9.778E-2
2 295
9 hsa-miR-140-5p:TargetScan hsa-miR-140-5p TargetScan 3.537E-4 1.116E-2
6.950E-2
1.004E-1
2 299
10 hsa-miR-10a*:mirSVR highEffct hsa-miR-10a*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 4.355E-4 1.237E-2
7.703E-2
1.237E-1
2 332
11 hsa-miR-1203:mirSVR lowEffct hsa-miR-1203:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 4.920E-4 1.270E-2
7.911E-2
1.397E-1
2 353
12 hsa-miR-125b-1*:mirSVR lowEffct hsa-miR-125b-1*:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 5.606E-4 1.310E-2
8.158E-2
1.592E-1
2 377
13 hsa-miR-3200:mirSVR highEffct hsa-miR-3200:mirSVR nonconserved highEffect-0.5 MicroRNA.org 5.996E-4 1.310E-2
8.158E-2
1.703E-1
2 390
14 hsa-miR-142-3p.2:TargetScan hsa-miR-142-3p.2 TargetScan 7.244E-4 1.470E-2
9.152E-2
2.057E-1
2 429
15 hsa-miR-1915*:mirSVR highEffct hsa-miR-1915*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.354E-4 1.582E-2
9.851E-2
2.373E-1
2 461
16 hsa-miR-1203:PITA hsa-miR-1203:PITA TOP PITA 1.646E-3 2.922E-2
1.820E-1
4.675E-1
1 17
17 hsa-miR-409-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.000E-3 4.023E-2
2.506E-1
8.520E-1
1 31
18 GGTAACC,MIR-409-5P:MSigDB GGTAACC,MIR-409-5P:MSigDB MSigDB 3.000E-3 4.023E-2
2.506E-1
8.520E-1
1 31
19 hsa-miR-6755-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.193E-3 4.023E-2
2.506E-1
9.069E-1
1 33
20 hsa-miR-4256:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.387E-3 4.023E-2
2.506E-1
9.618E-1
1 35
21 hsa-miR-4750-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.676E-3 4.023E-2
2.506E-1
1.000E0
1 38
22 hsa-miR-598:PITA hsa-miR-598:PITA TOP PITA 4.739E-3 4.023E-2
2.506E-1
1.000E0
1 49
23 hsa-miR-4765:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.125E-3 4.023E-2
2.506E-1
1.000E0
1 53
24 AGTCAGC,MIR-345:MSigDB AGTCAGC,MIR-345:MSigDB MSigDB 5.607E-3 4.023E-2
2.506E-1
1.000E0
1 58
25 hsa-miR-2277-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 5.703E-3 4.023E-2
2.506E-1
1.000E0
1 59
26 hsa-miR-7106-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.667E-3 4.023E-2
2.506E-1
1.000E0
1 69
27 hsa-miR-6126:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 6.763E-3 4.023E-2
2.506E-1
1.000E0
1 70
28 hsa-miR-299-3p:Functional MTI Functional MTI miRTarbase 6.860E-3 4.023E-2
2.506E-1
1.000E0
1 71
29 CTCAAGA,MIR-526B:MSigDB CTCAAGA,MIR-526B:MSigDB MSigDB 6.956E-3 4.023E-2
2.506E-1
1.000E0
1 72
30 CTCCAAG,MIR-432:MSigDB CTCCAAG,MIR-432:MSigDB MSigDB 7.341E-3 4.023E-2
2.506E-1
1.000E0
1 76
31 hsa-miR-4648:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.341E-3 4.023E-2
2.506E-1
1.000E0
1 76
32 hsa-miR-4493:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.438E-3 4.023E-2
2.506E-1
1.000E0
1 77
33 hsa-miR-4654:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.534E-3 4.023E-2
2.506E-1
1.000E0
1 78
34 hsa-miR-4769-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.726E-3 4.023E-2
2.506E-1
1.000E0
1 80
35 TTGGGAG,MIR-150:MSigDB TTGGGAG,MIR-150:MSigDB MSigDB 7.726E-3 4.023E-2
2.506E-1
1.000E0
1 80
36 hsa-miR-769-5p:PITA hsa-miR-769-5p:PITA TOP PITA 8.015E-3 4.023E-2
2.506E-1
1.000E0
1 83
37 hsa-miR-6810-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.496E-3 4.023E-2
2.506E-1
1.000E0
1 88
38 hsa-miR-20a-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.881E-3 4.023E-2
2.506E-1
1.000E0
1 92
39 hsa-miR-296-3p:PITA hsa-miR-296-3p:PITA TOP PITA 8.977E-3 4.023E-2
2.506E-1
1.000E0
1 93
40 hsa-miR-4290:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.073E-3 4.023E-2
2.506E-1
1.000E0
1 94
41 hsa-miR-4433b-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.362E-3 4.023E-2
2.506E-1
1.000E0
1 97
42 hsa-miR-409-5p:TargetScan hsa-miR-409-5p TargetScan 9.362E-3 4.023E-2
2.506E-1
1.000E0
1 97
43 hsa-miR-6893-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.362E-3 4.023E-2
2.506E-1
1.000E0
1 97
44 hsa-miR-4308:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.650E-3 4.023E-2
2.506E-1
1.000E0
1 100
45 hsa-miR-4303:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.650E-3 4.023E-2
2.506E-1
1.000E0
1 100
46 GTGTTGA,MIR-505:MSigDB GTGTTGA,MIR-505:MSigDB MSigDB 9.746E-3 4.023E-2
2.506E-1
1.000E0
1 101
47 TGCAAAC,MIR-452:MSigDB TGCAAAC,MIR-452:MSigDB MSigDB 1.013E-2 4.023E-2
2.506E-1
1.000E0
1 105
48 hsa-miR-511-5p:Functional MTI Functional MTI miRTarbase 1.013E-2 4.023E-2
2.506E-1
1.000E0
1 105
49 hsa-miR-720:mirSVR highEffct hsa-miR-720:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.071E-2 4.023E-2
2.506E-1
1.000E0
1 111
50 hsa-miR-382-5p:Functional MTI Functional MTI miRTarbase 1.071E-2 4.023E-2
2.506E-1
1.000E0
1 111
Show 45 more annotations

17: Drug [Display Chart] 7 input genes in category / 1048 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID000166931 phosphine oxide Stitch 1.576E-8 1.652E-5 1.244E-4 1.652E-5 4 107
2 ctd:D011280 Pregnanolone CTD 4.042E-8 2.118E-5 1.595E-4 4.236E-5 3 25
3 CID000015133 Tr-J Stitch 8.709E-8 3.042E-5 2.292E-4 9.127E-5 3 32
4 CID000057056 AC1L1M7Y Stitch 9.155E-7 2.399E-4 1.807E-3 9.594E-4 3 69
5 ctd:D004092 20-alpha-Dihydroprogesterone CTD 2.895E-6 6.069E-4 4.571E-3 3.034E-3 2 9
6 CID000091752 Rugby Stitch 3.619E-6 6.321E-4 4.761E-3 3.792E-3 2 10
7 CID000114924 tetradecylthioacetic acid Stitch 5.919E-6 8.213E-4 6.186E-3 6.203E-3 3 128
8 CID000075994 benzylpiperazine Stitch 6.270E-6 8.213E-4 6.186E-3 6.570E-3 2 13
9 CID000151900 4-methylthioamphetamine Stitch 1.373E-5 1.599E-3 1.204E-2 1.439E-2 2 19
10 CID000042619 pyrazolate Stitch 1.686E-5 1.767E-3 1.331E-2 1.767E-2 2 21
11 CID000410253 copper complex Stitch 2.607E-5 2.484E-3 1.871E-2 2.733E-2 2 26
12 CID000129920 JS-1 Stitch 3.032E-5 2.625E-3 1.977E-2 3.177E-2 2 28
13 ctd:D000622 Aminolevulinic Acid CTD 3.256E-5 2.625E-3 1.977E-2 3.412E-2 2 29
14 CID000068205 fluorescin Stitch 5.334E-5 3.850E-3 2.900E-2
5.591E-2
2 37
15 CID000043849 1H-3 Stitch 5.630E-5 3.850E-3 2.900E-2
5.900E-2
2 38
16 CID000002526 beta-glycerophosphate Stitch 6.245E-5 3.850E-3 2.900E-2
6.545E-2
2 40
17 CID000000255 BNPP Stitch 6.245E-5 3.850E-3 2.900E-2
6.545E-2
2 40
18 CID000003300 SA-7 Stitch 6.891E-5 4.012E-3 3.022E-2
7.222E-2
2 42
19 CID000443046 gamma-cyhalothrin Stitch 8.646E-5 4.769E-3 3.592E-2
9.061E-2
2 47
20 CID000072508 pip-pip Stitch 1.816E-4 9.281E-3
6.991E-2
1.904E-1
2 68
21 CID000445522 H-Mn Stitch 1.981E-4 9.281E-3
6.991E-2
2.076E-1
2 71
22 CID000028015 Na2S Stitch 1.981E-4 9.281E-3
6.991E-2
2.076E-1
2 71
23 CID000092745 5 beta-pregnane-3,20-dione Stitch 2.037E-4 9.281E-3
6.991E-2
2.135E-1
2 72
24 CID000006956 phthalamide Stitch 2.579E-4 9.733E-3
7.331E-2
2.702E-1
2 81
25 CID000178040 Marksman Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
26 CID005381230 caerulomycin Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
27 CID009809282 tris(4-iodophenyl)amine Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
28 CID000084788 glufosinate metabolite Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
29 CID012090074 N-(8-quinolyl)pyridine-2-carboxamide Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
30 CID000355383 AC1L769V Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
31 CID000428024 4-bromo-2-thiazolamine Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
32 CID004141519 Doob Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
33 CID000014591 prolintane Stitch 3.065E-4 9.733E-3
7.331E-2
3.212E-1
1 1
34 CID006437335 NSC 402447 Stitch 3.399E-4 1.048E-2
7.891E-2
3.562E-1
2 93
35 CID000003829 AC1L1GT5 Stitch 3.546E-4 1.062E-2
7.998E-2
3.716E-1
2 95
36 CID009549299 EGFR inhibitor Stitch 5.650E-4 1.396E-2
1.052E-1
5.921E-1
2 120
37 CID000442867 palustrine Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
38 CID000010757 tear gas Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
39 CID000141310 etioporphyrin III Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
40 CID000004527 AC1L1ID7 Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
41 CID009571169 CHEMBL83995 Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
42 CID000082350 3-hydroxypropyl laurate Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
43 CID000028211 copper(II) perchlorate Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
44 CID000097875 2-biphenylyl glycidyl ether Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
45 CID000073277 chloropyrazine Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
46 CID000061250 amyl nitrate Stitch 6.129E-4 1.396E-2
1.052E-1
6.423E-1
1 2
47 ctd:C010176 halofuginone CTD 6.525E-4 1.455E-2
1.096E-1
6.838E-1
2 129
48 ctd:C067311 docetaxel CTD 7.037E-4 1.527E-2
1.151E-1
7.375E-1
2 134
49 CID000004607 Bactocill Stitch 7.142E-4 1.527E-2
1.151E-1
7.485E-1
2 135
50 CID000002592 NSC625381 Stitch 8.231E-4 1.554E-2
1.170E-1
8.626E-1
2 145
Show 45 more annotations

18: Disease [Display Chart] 7 input genes in category / 437 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0007959 Charcot-Marie-Tooth Disease DisGeNET Curated 4.595E-15 1.236E-12 8.231E-12 2.008E-12 7 148
2 C1847584 Distal sensory impairment DisGeNET Curated 5.658E-15 1.236E-12 8.231E-12 2.472E-12 6 52
3 C1858729 Decreased motor NCV DisGeNET Curated 5.932E-14 8.641E-12 5.753E-11 2.592E-11 5 22
4 C0598589 Inherited neuropathies DisGeNET BeFree 1.912E-12 2.089E-10 1.391E-9 8.356E-10 5 42
5 C0751036 Hereditary Motor and Sensory Neuropathy Type I DisGeNET BeFree 8.701E-12 7.605E-10 5.063E-9 3.802E-9 4 13
6 C0427065 Distal muscle weakness DisGeNET Curated 1.452E-11 9.062E-10 6.034E-9 6.343E-9 5 62
7 C1864696 Distal limb muscle weakness due to peripheral neuropathy DisGeNET Curated 1.452E-11 9.062E-10 6.034E-9 6.343E-9 5 62
8 C0393814 Hereditary liability to pressure palsies DisGeNET Curated 1.661E-11 9.071E-10 6.040E-9 7.257E-9 4 15
9 C0151313 Sensory neuropathy DisGeNET Curated 4.425E-11 2.059E-9 1.371E-8 1.934E-8 5 77
10 C1847906 Onion bulb formation DisGeNET Curated 4.713E-11 2.059E-9 1.371E-8 2.059E-8 4 19
11 C1858285 Decreased number of large and small myelinated fibers DisGeNET Curated 5.890E-11 2.340E-9 1.558E-8 2.574E-8 4 20
12 C0728829 Congenital pes cavus DisGeNET Curated 9.285E-11 3.381E-9 2.251E-8 4.058E-8 5 89
13 C1136179 Hammer Toe DisGeNET Curated 1.076E-10 3.617E-9 2.408E-8 4.702E-8 4 23
14 C0427149 Gait, Drop Foot DisGeNET Curated 1.291E-10 3.733E-9 2.485E-8 5.642E-8 4 24
15 C0027888 Hereditary Motor and Sensory Neuropathies DisGeNET Curated 1.291E-10 3.733E-9 2.485E-8 5.642E-8 4 24
16 C0442874 Neuropathy DisGeNET Curated 1.367E-10 3.733E-9 2.485E-8 5.972E-8 6 269
17 OMIN:145900 HYPERTROPHIC NEUROPATHY OF DEJERINE-SOTTAS OMIM 1.974E-10 4.657E-9 3.101E-8 8.626E-8 3 4
18 cv:C0011195 Dejerine-Sottas disease Clinical Variations 1.974E-10 4.657E-9 3.101E-8 8.626E-8 3 4
19 C0085684 Foot-drop DisGeNET Curated 2.131E-10 4.657E-9 3.101E-8 9.314E-8 4 27
20 C1866141 Foot dorsiflexor weakness DisGeNET Curated 2.131E-10 4.657E-9 3.101E-8 9.314E-8 4 27
21 C1832776 Hypertrophic nerve changes DisGeNET Curated 4.934E-10 9.801E-9 6.525E-8 2.156E-7 3 5
22 C0037921 Spinal ataxia DisGeNET Curated 4.934E-10 9.801E-9 6.525E-8 2.156E-7 3 5
23 C0700078 Decreased tendon reflex DisGeNET Curated 5.665E-10 1.076E-8 7.166E-8 2.476E-7 5 127
24 C4025799 Ulnar claw DisGeNET Curated 9.866E-10 1.796E-8 1.196E-7 4.311E-7 3 6
25 C0393818 Congenital hypomyelinating neuropathy DisGeNET Curated 1.726E-9 3.017E-8 2.009E-7 7.544E-7 3 7
26 C1843077 Segmental demyelination/remyelination DisGeNET Curated 2.761E-9 4.641E-8 3.090E-7 1.207E-6 3 8
27 C1848736 Distal amyotrophy DisGeNET Curated 3.276E-9 5.301E-8 3.530E-7 1.431E-6 4 52
28 C0240991 Ataxia, Sensory DisGeNET Curated 5.915E-9 9.232E-8 6.147E-7 2.585E-6 3 10
29 C1806780 Cerebrospinal fluid protein increased above normal DisGeNET Curated 1.793E-8 2.702E-7 1.799E-6 7.835E-6 3 14
30 C0031117 Peripheral Neuropathy DisGeNET Curated 2.875E-8 4.188E-7 2.788E-6 1.256E-5 5 277
31 C1854494 Slow progression DisGeNET Curated 3.074E-8 4.198E-7 2.795E-6 1.343E-5 4 90
32 C0011195 Dejerine-Sottas Disease (disorder) DisGeNET Curated 3.074E-8 4.198E-7 2.795E-6 1.343E-5 4 90
33 C0241772 Reflex, Deep Tendon, Absent DisGeNET Curated 3.511E-8 4.384E-7 2.919E-6 1.534E-5 4 93
34 C0234146 Absent reflex DisGeNET Curated 3.511E-8 4.384E-7 2.919E-6 1.534E-5 4 93
35 C0278124 Absent tendon reflex DisGeNET Curated 3.511E-8 4.384E-7 2.919E-6 1.534E-5 4 93
36 C0270911 Charcot-Marie-Tooth Disease, Type Ia (disorder) DisGeNET Curated 7.574E-8 9.194E-7 6.122E-6 3.310E-5 3 22
37 C1867138 Upper limb postural tremor DisGeNET Curated 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
38 C0028643 Numbness DisGeNET BeFree 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
39 C0027743 Nerve compression syndrome DisGeNET BeFree 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
40 OMIN:605253 NEUROPATHY, CONGENITAL HYPOMYELINATING OMIM 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
41 C1861675 Cold-induced muscle cramps DisGeNET Curated 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
42 OMIN:180800 ROUSSY-LEVY HEREDITARY AREFLEXIC DYSTASIA OMIM 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
43 C1510429 Entrapment Neuropathies DisGeNET BeFree 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
44 cv:C0205713 Roussy-Lévy syndrome Clinical Variations 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
45 C0205713 Roussy-Levy Syndrome (disorder) DisGeNET Curated 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
46 cv:C0393818 Congenital hypomyelinating neuropathy Clinical Variations 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
47 C0474520 Myokymia, Generalized DisGeNET BeFree 1.599E-7 1.487E-6 9.902E-6 6.990E-5 2 2
48 C0270914 Hereditary Motor and Sensory-Neuropathy Type II DisGeNET Curated 1.994E-7 1.815E-6 1.209E-5 8.713E-5 3 30
49 C1854301 Motor delay DisGeNET Curated 2.481E-7 2.169E-6 1.444E-5 1.084E-4 4 151
50 C4020874 No development of motor milestones DisGeNET Curated 2.481E-7 2.169E-6 1.444E-5 1.084E-4 4 151
Show 45 more annotations