Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc4_7, positive side

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1: GO: Molecular Function [Display Chart] 7 input genes in category / 125 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0035851 Krueppel-associated box domain binding 3.618E-7 4.522E-5 2.446E-4 4.522E-5 2 3
2 GO:0031490 chromatin DNA binding 3.150E-6 1.969E-4 1.065E-3 3.938E-4 3 85
3 GO:0031078 histone deacetylase activity (H3-K14 specific) 7.946E-6 2.483E-4 1.343E-3 9.933E-4 2 12
4 GO:0032041 NAD-dependent histone deacetylase activity (H3-K14 specific) 7.946E-6 2.483E-4 1.343E-3 9.933E-4 2 12
5 GO:0017136 NAD-dependent histone deacetylase activity 1.444E-5 3.408E-4 1.844E-3 1.805E-3 2 16
6 GO:0034979 NAD-dependent protein deacetylase activity 1.636E-5 3.408E-4 1.844E-3 2.045E-3 2 17
7 GO:0001047 core promoter binding 2.273E-5 4.059E-4 2.196E-3 2.841E-3 3 164
8 GO:0001103 RNA polymerase II repressing transcription factor binding 4.538E-5 7.091E-4 3.836E-3 5.673E-3 2 28
9 GO:0031492 nucleosomal DNA binding 5.221E-5 7.251E-4 3.922E-3 6.526E-3 2 30
10 GO:0051059 NF-kappaB binding 7.134E-5 8.918E-4 4.824E-3 8.918E-3 2 35
11 GO:0004407 histone deacetylase activity 1.031E-4 1.126E-3 6.093E-3 1.289E-2 2 42
12 GO:0033558 protein deacetylase activity 1.081E-4 1.126E-3 6.093E-3 1.352E-2 2 43
13 GO:0031491 nucleosome binding 1.185E-4 1.139E-3 6.163E-3 1.481E-2 2 45
14 GO:0070491 repressing transcription factor binding 2.113E-4 1.886E-3 1.021E-2 2.641E-2 2 60
15 GO:0019213 deacetylase activity 2.330E-4 1.942E-3 1.050E-2 2.913E-2 2 63
16 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 2.558E-4 1.998E-3 1.081E-2 3.197E-2 2 66
17 GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding 2.961E-4 2.177E-3 1.178E-2 3.701E-2 2 71
18 GO:0071164 RNA trimethylguanosine synthase activity 3.751E-4 2.468E-3 1.335E-2 4.689E-2 1 1
19 GO:0008995 ribonuclease E activity 3.751E-4 2.468E-3 1.335E-2 4.689E-2 1 1
20 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 4.755E-4 2.972E-3 1.608E-2
5.944E-2
 2 90
21 GO:0001158 enhancer sequence-specific DNA binding 5.077E-4 3.022E-3 1.635E-2
6.346E-2
 2 93
22 GO:0035326 enhancer binding 6.589E-4 3.581E-3 1.937E-2
8.236E-2
 2 106
23 GO:0031072 heat shock protein binding 6.589E-4 3.581E-3 1.937E-2
8.236E-2
 2 106
24 GO:0001046 core promoter sequence-specific DNA binding 7.748E-4 4.036E-3 2.183E-2
9.685E-2
 2 115
25 GO:0001085 RNA polymerase II transcription factor binding 8.155E-4 4.078E-3 2.206E-2
1.019E-1
 2 118
26 GO:0016279 protein-lysine N-methyltransferase activity 8.714E-4 4.100E-3 2.218E-2
1.089E-1
 2 122
27 GO:0016278 lysine N-methyltransferase activity 8.856E-4 4.100E-3 2.218E-2
1.107E-1
 2 123
28 GO:0001226 RNA polymerase II transcription corepressor binding 1.125E-3 4.748E-3 2.569E-2
1.406E-1
 1 3
29 GO:0034739 histone deacetylase activity (H4-K16 specific) 1.125E-3 4.748E-3 2.569E-2
1.406E-1
 1 3
30 GO:0008170 N-methyltransferase activity 1.161E-3 4.748E-3 2.569E-2
1.452E-1
 2 141
31 GO:0008276 protein methyltransferase activity 1.178E-3 4.748E-3 2.569E-2
1.472E-1
 2 142
32 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.278E-3 4.993E-3 2.701E-2
1.598E-1
 2 148
33 GO:0001224 RNA polymerase II transcription cofactor binding 1.500E-3 5.681E-3 3.073E-2
1.875E-1
 1 4
34 GO:0070878 primary miRNA binding 1.874E-3 6.607E-3 3.574E-2
2.343E-1
 1 5
35 GO:0046976 histone methyltransferase activity (H3-K27 specific) 1.874E-3 6.607E-3 3.574E-2
2.343E-1
 1 5
36 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity 1.903E-3 6.607E-3 3.574E-2
2.379E-1
 2 181
37 GO:0008168 methyltransferase activity 2.622E-3 8.859E-3 4.792E-2
3.278E-1
 2 213
38 GO:0016741 transferase activity, transferring one-carbon groups 2.921E-3 9.607E-3
5.197E-2
3.651E-1
 2 225
39 GO:0001222 transcription corepressor binding 3.746E-3 1.201E-2
6.494E-2
4.682E-1
 1 10
40 GO:0004865 protein serine/threonine phosphatase inhibitor activity 4.120E-3 1.287E-2
6.964E-2
5.150E-1
 1 11
41 GO:1990841 promoter-specific chromatin binding 6.361E-3 1.939E-2
1.049E-1
7.951E-1
 1 17
42 GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding 8.075E-3 2.403E-2
1.300E-1
1.000E0
 2 379
43 GO:0000987 proximal promoter sequence-specific DNA binding 8.876E-3 2.580E-2
1.396E-1
1.000E0
 2 398
44 GO:0001221 transcription cofactor binding 1.120E-2 3.182E-2
1.721E-1
1.000E0
 1 30
45 GO:0030544 Hsp70 protein binding 1.269E-2 3.524E-2
1.906E-1
1.000E0
 1 34
46 GO:0004864 protein phosphatase inhibitor activity 1.417E-2 3.616E-2
1.956E-1
1.000E0
 1 38
47 GO:0019212 phosphatase inhibitor activity 1.528E-2 3.616E-2
1.956E-1
1.000E0
 1 41
48 GO:0018024 histone-lysine N-methyltransferase activity 1.713E-2 3.616E-2
1.956E-1
1.000E0
 1 46
49 GO:0042054 histone methyltransferase activity 2.193E-2 3.616E-2
1.956E-1
1.000E0
 1 59
50 GO:0033613 activating transcription factor binding 2.266E-2 3.616E-2
1.956E-1
1.000E0
 1 61
Show 45 more annotations

2: GO: Biological Process [Display Chart] 7 input genes in category / 473 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0035984 cellular response to trichostatin A 7.264E-7 1.145E-4 7.716E-4 3.436E-4 2 4
2 GO:0035983 response to trichostatin A 7.264E-7 1.145E-4 7.716E-4 3.436E-4 2 4
3 GO:0061198 fungiform papilla formation 7.264E-7 1.145E-4 7.716E-4 3.436E-4 2 4
4 GO:0061197 fungiform papilla morphogenesis 1.815E-6 1.851E-4 1.247E-3 8.586E-4 2 6
5 GO:0061196 fungiform papilla development 2.541E-6 1.851E-4 1.247E-3 1.202E-3 2 7
6 GO:0060789 hair follicle placode formation 2.541E-6 1.851E-4 1.247E-3 1.202E-3 2 7
7 GO:0021766 hippocampus development 2.740E-6 1.851E-4 1.247E-3 1.296E-3 3 81
8 GO:0051153 regulation of striated muscle cell differentiation 5.177E-6 2.650E-4 1.785E-3 2.449E-3 3 100
9 GO:0070933 histone H4 deacetylation 5.442E-6 2.650E-4 1.785E-3 2.574E-3 2 10
10 GO:0043587 tongue morphogenesis 6.650E-6 2.650E-4 1.785E-3 3.146E-3 2 11
11 GO:0010870 positive regulation of receptor biosynthetic process 6.650E-6 2.650E-4 1.785E-3 3.146E-3 2 11
12 GO:0021761 limbic system development 6.898E-6 2.650E-4 1.785E-3 3.263E-3 3 110
13 GO:0014013 regulation of gliogenesis 7.283E-6 2.650E-4 1.785E-3 3.445E-3 3 112
14 GO:0061029 eyelid development in camera-type eye 1.269E-5 4.286E-4 2.888E-3 6.001E-3 2 15
15 GO:0071236 cellular response to antibiotic 1.848E-5 5.140E-4 3.463E-3 8.739E-3 2 18
16 GO:0071696 ectodermal placode development 2.065E-5 5.140E-4 3.463E-3 9.766E-3 2 19
17 GO:0071697 ectodermal placode morphogenesis 2.065E-5 5.140E-4 3.463E-3 9.766E-3 2 19
18 GO:0060788 ectodermal placode formation 2.065E-5 5.140E-4 3.463E-3 9.766E-3 2 19
19 GO:0048714 positive regulation of oligodendrocyte differentiation 2.065E-5 5.140E-4 3.463E-3 9.766E-3 2 19
20 GO:2000757 negative regulation of peptidyl-lysine acetylation 2.294E-5 5.274E-4 3.553E-3 1.085E-2 2 20
21 GO:0070734 histone H3-K27 methylation 2.535E-5 5.274E-4 3.553E-3 1.199E-2 2 21
22 GO:0010869 regulation of receptor biosynthetic process 2.535E-5 5.274E-4 3.553E-3 1.199E-2 2 21
23 GO:0051147 regulation of muscle cell differentiation 2.637E-5 5.274E-4 3.553E-3 1.247E-2 3 172
24 GO:0021543 pallium development 2.777E-5 5.274E-4 3.553E-3 1.313E-2 3 175
25 GO:0070932 histone H3 deacetylation 2.788E-5 5.274E-4 3.553E-3 1.319E-2 2 22
26 GO:1901984 negative regulation of protein acetylation 3.053E-5 5.553E-4 3.741E-3 1.444E-2 2 23
27 GO:0043586 tongue development 3.329E-5 5.833E-4 3.930E-3 1.575E-2 2 24
28 GO:0032800 receptor biosynthetic process 3.919E-5 6.621E-4 4.461E-3 1.854E-2 2 26
29 GO:0009913 epidermal cell differentiation 4.137E-5 6.672E-4 4.495E-3 1.957E-2 3 200
30 GO:0097237 cellular response to toxic substance 4.232E-5 6.672E-4 4.495E-3 2.002E-2 2 27
31 GO:0007623 circadian rhythm 5.062E-5 7.723E-4 5.203E-3 2.394E-2 3 214
32 GO:0051154 negative regulation of striated muscle cell differentiation 5.242E-5 7.748E-4 5.220E-3 2.479E-2 2 30
33 GO:0010718 positive regulation of epithelial to mesenchymal transition 6.755E-5 9.398E-4 6.332E-3 3.195E-2 2 34
34 GO:0001975 response to amphetamine 6.755E-5 9.398E-4 6.332E-3 3.195E-2 2 34
35 GO:0034599 cellular response to oxidative stress 7.756E-5 1.048E-3 7.062E-3 3.669E-2 3 247
36 GO:0048713 regulation of oligodendrocyte differentiation 8.459E-5 1.111E-3 7.488E-3 4.001E-2 2 38
37 GO:0045687 positive regulation of glial cell differentiation 8.915E-5 1.124E-3 7.575E-3 4.217E-2 2 39
38 GO:0021537 telencephalon development 9.033E-5 1.124E-3 7.575E-3 4.273E-2 3 260
39 GO:0032732 positive regulation of interleukin-1 production 1.035E-4 1.235E-3 8.318E-3 4.897E-2 2 42
40 GO:0043414 macromolecule methylation 1.044E-4 1.235E-3 8.318E-3 4.938E-2 3 273
41 GO:0042063 gliogenesis 1.114E-4 1.285E-3 8.655E-3
5.267E-2
 3 279
42 GO:0051146 striated muscle cell differentiation 1.236E-4 1.392E-3 9.379E-3
5.847E-2
 3 289
43 GO:0046677 response to antibiotic 1.531E-4 1.684E-3 1.134E-2
7.240E-2
 2 51
44 GO:0014075 response to amine 1.592E-4 1.711E-3 1.153E-2
7.528E-2
 2 52
45 GO:2000738 positive regulation of stem cell differentiation 1.717E-4 1.805E-3 1.216E-2
8.121E-2
 2 54
46 GO:0008544 epidermis development 1.999E-4 2.056E-3 1.385E-2
9.457E-2
 3 340
47 GO:0032259 methylation 2.160E-4 2.101E-3 1.416E-2
1.021E-1
 3 349
48 GO:0014015 positive regulation of gliogenesis 2.193E-4 2.101E-3 1.416E-2
1.037E-1
 2 61
49 GO:0051148 negative regulation of muscle cell differentiation 2.193E-4 2.101E-3 1.416E-2
1.037E-1
 2 61
50 GO:0032922 circadian regulation of gene expression 2.266E-4 2.101E-3 1.416E-2
1.072E-1
 2 62
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 7 input genes in category / 29 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0016580 Sin3 complex 1.050E-5 1.143E-4 4.529E-4 3.044E-4 2 14
2 GO:0035098 ESC/E(Z) complex 1.384E-5 1.143E-4 4.529E-4 4.013E-4 2 16
3 GO:0070822 Sin3-type complex 1.568E-5 1.143E-4 4.529E-4 4.548E-4 2 17
4 GO:0090545 CHD-type complex 1.971E-5 1.143E-4 4.529E-4 5.716E-4 2 19
5 GO:0016581 NuRD complex 1.971E-5 1.143E-4 4.529E-4 5.716E-4 2 19
6 GO:0090568 nuclear transcriptional repressor complex 3.741E-5 1.808E-4 7.164E-4 1.085E-3 2 26
7 GO:0031519 PcG protein complex 1.136E-4 4.706E-4 1.864E-3 3.294E-3 2 45
8 GO:0000790 nuclear chromatin 1.619E-4 5.869E-4 2.325E-3 4.695E-3 3 324
9 GO:0000118 histone deacetylase complex 2.234E-4 7.198E-4 2.852E-3 6.478E-3 2 63
10 GO:0035097 histone methyltransferase complex 3.001E-4 8.129E-4 3.220E-3 8.702E-3 2 73
11 GO:0070603 SWI/SNF superfamily-type complex 3.083E-4 8.129E-4 3.220E-3 8.942E-3 2 74
12 GO:0017053 transcriptional repressor complex 3.514E-4 8.493E-4 3.364E-3 1.019E-2 2 79
13 GO:0000792 heterochromatin 4.261E-4 9.505E-4 3.766E-3 1.236E-2 2 87
14 GO:0034708 methyltransferase complex 4.764E-4 9.868E-4 3.909E-3 1.381E-2 2 92
15 GO:0000785 chromatin 5.374E-4 1.039E-3 4.116E-3 1.558E-2 3 487
16 GO:0034669 integrin alpha4-beta7 complex 7.344E-4 1.331E-3 5.273E-3 2.130E-2 1 2
17 GO:0090571 RNA polymerase II transcription repressor complex 2.568E-3 4.381E-3 1.736E-2
7.448E-2
 1 7
18 GO:0016604 nuclear body 7.168E-3 1.115E-2 4.416E-2
2.079E-1
 2 364
19 GO:0005667 transcription factor complex 7.321E-3 1.115E-2 4.416E-2
2.123E-1
 2 368
20 GO:0045120 pronucleus 7.688E-3 1.115E-2 4.416E-2
2.229E-1
 1 21
21 GO:0008305 integrin complex 1.097E-2 1.446E-2
5.727E-2
3.180E-1
 1 30
22 GO:0098636 protein complex involved in cell adhesion 1.097E-2 1.446E-2
5.727E-2
3.180E-1
 1 30
23 GO:0015030 Cajal body 1.967E-2 2.480E-2
9.824E-2
5.703E-1
 1 54
24 GO:0030532 small nuclear ribonucleoprotein complex 2.219E-2 2.681E-2
1.062E-1
6.435E-1
 1 61
25 GO:0005657 replication fork 2.435E-2 2.825E-2
1.119E-1
7.062E-1
 1 67
Show 20 more annotations

4: Human Phenotype [Display Chart] 2 input genes in category / 507 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 7 input genes in category / 393 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0012404 abnormal nail color 3.917E-7 7.698E-5 5.044E-4 1.540E-4 2 2
2 MP:0004027 trisomy 3.917E-7 7.698E-5 5.044E-4 1.540E-4 2 2
3 MP:0001267 enlarged chest 1.095E-5 1.434E-3 9.397E-3 4.302E-3 2 8
4 MP:0010682 abnormal hair follicle infundibulum morphology 2.577E-5 2.221E-3 1.455E-2 1.013E-2 2 12
5 MP:0008209 decreased pre-B cell number 3.542E-5 2.221E-3 1.455E-2 1.392E-2 3 106
6 MP:0005432 abnormal pro-B cell morphology 4.177E-5 2.221E-3 1.455E-2 1.642E-2 3 112
7 MP:0005093 decreased B cell proliferation 4.405E-5 2.221E-3 1.455E-2 1.731E-2 3 114
8 MP:0005090 increased double-negative T cell number 4.521E-5 2.221E-3 1.455E-2 1.777E-2 3 115
9 MP:0000575 increased foot pad pigmentation 5.302E-5 2.315E-3 1.517E-2 2.084E-2 2 17
10 MP:0030051 increased foot pigmentation 5.963E-5 2.343E-3 1.535E-2 2.343E-2 2 18
11 MP:0002403 abnormal pre-B cell morphology 6.983E-5 2.495E-3 1.635E-2 2.744E-2 3 133
12 MP:0001282 short vibrissae 8.176E-5 2.678E-3 1.755E-2 3.213E-2 2 21
13 MP:0008255 decreased megakaryocyte cell number 1.468E-4 3.835E-3 2.513E-2
5.771E-2
 2 28
14 MP:0000574 abnormal foot pad morphology 1.468E-4 3.835E-3 2.513E-2
5.771E-2
 2 28
15 MP:0005017 decreased B cell number 1.474E-4 3.835E-3 2.513E-2
5.793E-2
 4 484
16 MP:0009543 abnormal thymus corticomedullary boundary morphology 1.689E-4 3.835E-3 2.513E-2
6.637E-2
 2 30
17 MP:0002407 abnormal double-negative T cell morphology 1.746E-4 3.835E-3 2.513E-2
6.861E-2
 3 181
18 MP:0005153 abnormal B cell proliferation 1.804E-4 3.835E-3 2.513E-2
7.089E-2
 3 183
19 MP:0000715 decreased thymocyte number 1.893E-4 3.835E-3 2.513E-2
7.438E-2
 3 186
20 MP:0009379 abnormal foot pigmentation 2.048E-4 3.835E-3 2.513E-2
8.048E-2
 2 33
21 MP:0005092 decreased double-positive T cell number 2.210E-4 3.835E-3 2.513E-2
8.686E-2
 3 196
22 MP:0001188 hyperpigmentation 2.306E-4 3.835E-3 2.513E-2
9.063E-2
 2 35
23 MP:0008217 abnormal B cell activation 2.312E-4 3.835E-3 2.513E-2
9.085E-2
 3 199
24 MP:0005573 increased pulmonary respiratory rate 2.441E-4 3.835E-3 2.513E-2
9.593E-2
 2 36
25 MP:0009541 increased thymocyte apoptosis 2.441E-4 3.835E-3 2.513E-2
9.593E-2
 2 36
26 MP:0004957 abnormal blastocyst morphology 2.634E-4 3.835E-3 2.513E-2
1.035E-1
 3 208
27 MP:0014137 abnormal preimplantation embryo morphology 2.634E-4 3.835E-3 2.513E-2
1.035E-1
 3 208
28 MP:0005287 narrow eye opening 2.868E-4 4.026E-3 2.638E-2
1.127E-1
 2 39
29 MP:0000579 abnormal nail morphology 3.018E-4 4.090E-3 2.680E-2
1.186E-1
 2 40
30 MP:0002408 abnormal double-positive T cell morphology 3.823E-4 4.909E-3 3.217E-2
1.502E-1
 3 236
31 MP:0000714 increased thymocyte number 3.997E-4 4.909E-3 3.217E-2
1.571E-1
 2 46
32 MP:0013501 increased fibroblast apoptosis 3.997E-4 4.909E-3 3.217E-2
1.571E-1
 2 46
33 MP:0008782 increased B cell apoptosis 4.174E-4 4.970E-3 3.257E-2
1.640E-1
 2 47
34 MP:0003671 abnormal eyelid aperture 4.538E-4 5.245E-3 3.437E-2
1.783E-1
 2 49
35 MP:0004134 abnormal chest morphology 4.725E-4 5.306E-3 3.476E-2
1.857E-1
 2 50
36 MP:0020414 abnormal fibroblast physiology 5.315E-4 5.745E-3 3.764E-2
2.089E-1
 3 264
37 MP:0005091 increased double-positive T cell number 5.513E-4 5.745E-3 3.764E-2
2.166E-1
 2 54
38 MP:0011096 embryonic lethality between implantation and somite formation, complete penetrance 5.555E-4 5.745E-3 3.764E-2
2.183E-1
 3 268
39 MP:0001825 arrested T cell differentiation 6.581E-4 6.325E-3 4.145E-2
2.586E-1
 2 59
40 MP:0008082 increased single-positive T cell number 6.581E-4 6.325E-3 4.145E-2
2.586E-1
 2 59
41 MP:0012050 decreased susceptilbility to retinal ischemic injury 6.760E-4 6.325E-3 4.145E-2
2.657E-1
 1 1
42 MP:0013740 Meibomian gland hyperplasia 6.760E-4 6.325E-3 4.145E-2
2.657E-1
 1 1
43 MP:0006205 embryonic lethality between implantation and somite formation 7.578E-4 6.602E-3 4.326E-2
2.978E-1
 3 298
44 MP:0003222 increased cardiomyocyte apoptosis 7.741E-4 6.602E-3 4.326E-2
3.042E-1
 2 64
45 MP:0005572 abnormal pulmonary respiratory rate 7.741E-4 6.602E-3 4.326E-2
3.042E-1
 2 64
46 MP:0009258 abnormal thymocyte apoptosis 7.984E-4 6.602E-3 4.326E-2
3.138E-1
 2 65
47 MP:0010296 increased hemolymphoid system tumor incidence 8.110E-4 6.602E-3 4.326E-2
3.187E-1
 3 305
48 MP:0001730 embryonic growth arrest 8.110E-4 6.602E-3 4.326E-2
3.187E-1
 3 305
49 MP:0004024 aneuploidy 8.231E-4 6.602E-3 4.326E-2
3.235E-1
 2 66
50 MP:0008208 decreased pro-B cell number 8.482E-4 6.667E-3 4.368E-2
3.333E-1
 2 67
Show 45 more annotations

6: Domain [Display Chart] 7 input genes in category / 56 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 IPR003084 His deacetylse 1 InterPro 7.177E-7 4.019E-5 1.853E-4 4.019E-5 2 4
2 3.40.800.20 - Gene3D 6.571E-6 7.360E-5 3.394E-4 3.680E-4 2 11
3 IPR023801 His deacetylse dom InterPro 6.571E-6 7.360E-5 3.394E-4 3.680E-4 2 11
4 PF00850 Hist deacetyl Pfam 6.571E-6 7.360E-5 3.394E-4 3.680E-4 2 11
5 IPR000286 His deacetylse InterPro 6.571E-6 7.360E-5 3.394E-4 3.680E-4 2 11
6 PF05603 DUF775 Pfam 3.736E-4 1.902E-3 8.772E-3 2.092E-2 1 1
7 IPR019012 RNA cap Gua-N2-MeTrfase InterPro 3.736E-4 1.902E-3 8.772E-3 2.092E-2 1 1
8 IPR031318 OPI10 InterPro 3.736E-4 1.902E-3 8.772E-3 2.092E-2 1 1
9 IPR015437 Integrin bsu-7 InterPro 3.736E-4 1.902E-3 8.772E-3 2.092E-2 1 1
10 PF09445 Methyltransf 15 Pfam 3.736E-4 1.902E-3 8.772E-3 2.092E-2 1 1
11 IPR008493 DUF775 InterPro 3.736E-4 1.902E-3 8.772E-3 2.092E-2 1 1
12 PS51633 CXC PROSITE 7.471E-4 2.789E-3 1.286E-2 4.184E-2 1 2
13 PF11616 EZH2 WD-Binding Pfam 7.471E-4 2.789E-3 1.286E-2 4.184E-2 1 2
14 IPR026489 CXC dom InterPro 7.471E-4 2.789E-3 1.286E-2 4.184E-2 1 2
15 IPR021654 EZH1/EZH2 InterPro 7.471E-4 2.789E-3 1.286E-2 4.184E-2 1 2
16 IPR033467 Tesmin/TSO1-like CXC InterPro 2.240E-3 6.269E-3 2.891E-2
1.254E-1
 1 6
17 PF08725 Integrin b cyt Pfam 2.240E-3 6.269E-3 2.891E-2
1.254E-1
 1 6
18 SM01114 CXC SMART 2.240E-3 6.269E-3 2.891E-2
1.254E-1
 1 6
19 IPR014836 Integrin bsu cyt dom InterPro 2.240E-3 6.269E-3 2.891E-2
1.254E-1
 1 6
20 SM01241 Integrin b cyt SMART 2.240E-3 6.269E-3 2.891E-2
1.254E-1
 1 6
21 PF07965 Integrin B tail Pfam 2.613E-3 6.269E-3 2.891E-2
1.463E-1
 1 7
22 IPR012896 Integrin bsu tail InterPro 2.613E-3 6.269E-3 2.891E-2
1.463E-1
 1 7
23 SM01242 Integrin B tail SMART 2.613E-3 6.269E-3 2.891E-2
1.463E-1
 1 7
24 IPR002369 Integrin bsu VWA InterPro 2.986E-3 6.269E-3 2.891E-2
1.672E-1
 1 8
25 SM00187 INB SMART 2.986E-3 6.269E-3 2.891E-2
1.672E-1
 1 8
26 PF00362 Integrin beta Pfam 2.986E-3 6.269E-3 2.891E-2
1.672E-1
 1 8
27 PS00243 INTEGRIN BETA PROSITE 3.358E-3 6.269E-3 2.891E-2
1.881E-1
 1 9
28 PF17205 PSI integrin Pfam 3.358E-3 6.269E-3 2.891E-2
1.881E-1
 1 9
29 IPR033760 Integin beta N InterPro 3.358E-3 6.269E-3 2.891E-2
1.881E-1
 1 9
30 IPR015812 Integrin bsu InterPro 3.358E-3 6.269E-3 2.891E-2
1.881E-1
 1 9
31 IPR032695 Integrin dom InterPro 9.305E-3 1.681E-2
7.751E-2
5.211E-1
 1 25
32 SM00240 FHA SMART 1.042E-2 1.823E-2
8.406E-2
5.833E-1
 1 28
33 PF00498 FHA Pfam 1.153E-2 1.899E-2
8.755E-2
6.455E-1
 1 31
34 PS50006 FHA DOMAIN PROSITE 1.153E-2 1.899E-2
8.755E-2
6.455E-1
 1 31
35 IPR000253 FHA dom InterPro 1.338E-2 2.081E-2
9.595E-2
7.490E-1
 1 36
36 2.60.200.20 - Gene3D 1.338E-2 2.081E-2
9.595E-2
7.490E-1
 1 36
37 PF00856 SET Pfam 1.522E-2 2.304E-2
1.062E-1
8.524E-1
 1 41
38 IPR016201 PSI InterPro 1.633E-2 2.389E-2
1.102E-1
9.143E-1
 1 44
39 SM00317 SET SMART 1.706E-2 2.389E-2
1.102E-1
9.556E-1
 1 46
40 SM00423 PSI SMART 1.706E-2 2.389E-2
1.102E-1
9.556E-1
 1 46
41 SM00717 SANT SMART 1.854E-2 2.398E-2
1.106E-1
1.000E0
 1 50
42 PS50280 SET PROSITE 1.854E-2 2.398E-2
1.106E-1
1.000E0
 1 50
43 IPR001214 SET dom InterPro 1.854E-2 2.398E-2
1.106E-1
1.000E0
 1 50
44 IPR001005 SANT/Myb InterPro 1.927E-2 2.398E-2
1.106E-1
1.000E0
 1 52
45 IPR008984 SMAD FHA domain InterPro 1.927E-2 2.398E-2
1.106E-1
1.000E0
 1 52
46 PF07974 EGF 2 Pfam 2.221E-2 2.646E-2
1.220E-1
1.000E0
 1 60
47 IPR013111 EGF extracell InterPro 2.221E-2 2.646E-2
1.220E-1
1.000E0
 1 60
48 3.40.50.410 - Gene3D 2.733E-2 3.188E-2
1.470E-1
1.000E0
 1 74
49 PS50234 VWFA PROSITE 3.024E-2 3.456E-2
1.594E-1
1.000E0
 1 82
50 SM00327 VWA SMART 3.097E-2 3.469E-2
1.600E-1
1.000E0
 1 84
Show 45 more annotations

7: Pathway [Display Chart] 6 input genes in category / 125 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269451 p75NTR negatively regulates cell cycle via SC1 BioSystems: REACTOME 2.901E-6 3.626E-4 1.962E-3 3.626E-4 2 6
2 1269734 Epigenetic regulation of gene expression BioSystems: REACTOME 3.474E-5 1.687E-3 9.125E-3 4.342E-3 3 152
3 M5290 Role of MEF2D in T-cell Apoptosis MSigDB C2 BIOCARTA (v6.0) 4.048E-5 1.687E-3 9.125E-3 5.060E-3 2 21
4 523016 Transcriptional misregulation in cancer BioSystems: KEGG 5.757E-5 1.799E-3 9.732E-3 7.196E-3 3 180
5 1383083 Regulation of TP53 Activity through Acetylation BioSystems: REACTOME 8.945E-5 2.236E-3 1.210E-2 1.118E-2 2 31
6 M2499 CARM1 and Regulation of the Estrogen Receptor MSigDB C2 BIOCARTA (v6.0) 1.144E-4 2.252E-3 1.218E-2 1.429E-2 2 35
7 137912 Hedgehog signaling events mediated by Gli proteins BioSystems: Pathway Interaction Database 1.815E-4 2.252E-3 1.218E-2 2.268E-2 2 44
8 1270433 Chromatin organization BioSystems: REACTOME 2.118E-4 2.252E-3 1.218E-2 2.648E-2 3 279
9 1270434 Chromatin modifying enzymes BioSystems: REACTOME 2.118E-4 2.252E-3 1.218E-2 2.648E-2 3 279
10 1269537 NOTCH1 Intracellular Domain Regulates Transcription BioSystems: REACTOME 2.162E-4 2.252E-3 1.218E-2 2.702E-2 2 48
11 83062 Notch signaling pathway BioSystems: KEGG 2.162E-4 2.252E-3 1.218E-2 2.702E-2 2 48
12 1269660 RNA Polymerase I Transcription Initiation BioSystems: REACTOME 2.162E-4 2.252E-3 1.218E-2 2.702E-2 2 48
13 1268890 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer BioSystems: REACTOME 3.161E-4 2.325E-3 1.257E-2 3.952E-2 2 58
14 1268891 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants BioSystems: REACTOME 3.161E-4 2.325E-3 1.257E-2 3.952E-2 2 58
15 1268889 Constitutive Signaling by NOTCH1 PEST Domain Mutants BioSystems: REACTOME 3.161E-4 2.325E-3 1.257E-2 3.952E-2 2 58
16 1268888 Signaling by NOTCH1 PEST Domain Mutants in Cancer BioSystems: REACTOME 3.161E-4 2.325E-3 1.257E-2 3.952E-2 2 58
17 1268883 Signaling by NOTCH1 in Cancer BioSystems: REACTOME 3.161E-4 2.325E-3 1.257E-2 3.952E-2 2 58
18 1340713 Longevity regulating pathway - multiple species BioSystems: KEGG 3.613E-4 2.509E-3 1.357E-2 4.517E-2 2 62
19 137997 Signaling events mediated by HDAC Class I BioSystems: Pathway Interaction Database 4.095E-4 2.560E-3 1.385E-2
5.119E-2
 2 66
20 137987 Regulation of Telomerase BioSystems: Pathway Interaction Database 4.095E-4 2.560E-3 1.385E-2
5.119E-2
 2 66
21 83116 Chronic myeloid leukemia BioSystems: KEGG 4.739E-4 2.821E-3 1.526E-2
5.924E-2
 2 71
22 1269535 Signaling by NOTCH1 BioSystems: REACTOME 5.148E-4 2.903E-3 1.570E-2
6.435E-2
 2 74
23 1383084 ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression BioSystems: REACTOME 5.573E-4 2.903E-3 1.570E-2
6.967E-2
 2 77
24 137963 Regulation of nuclear SMAD2/3 signaling BioSystems: Pathway Interaction Database 5.573E-4 2.903E-3 1.570E-2
6.967E-2
 2 77
25 169352 Regulation of Wnt-mediated beta catenin signaling and target gene transcription BioSystems: Pathway Interaction Database 5.866E-4 2.933E-3 1.587E-2
7.332E-2
 2 79
26 138014 Glucocorticoid receptor regulatory network BioSystems: Pathway Interaction Database 6.319E-4 3.038E-3 1.643E-2
7.898E-2
 2 82
27 1270436 HDACs deacetylate histones BioSystems: REACTOME 8.295E-4 3.840E-3 2.077E-2
1.037E-1
 2 94
28 1269445 p75 NTR receptor-mediated signalling BioSystems: REACTOME 9.382E-4 4.188E-3 2.266E-2
1.173E-1
 2 100
29 1269739 NoRC negatively regulates rRNA expression BioSystems: REACTOME 1.093E-3 4.397E-3 2.379E-2
1.367E-1
 2 108
30 1339125 Positive epigenetic regulation of rRNA expression BioSystems: REACTOME 1.113E-3 4.397E-3 2.379E-2
1.392E-1
 2 109
31 1269737 Negative epigenetic regulation of rRNA expression BioSystems: REACTOME 1.154E-3 4.397E-3 2.379E-2
1.443E-1
 2 111
32 1269658 RNA Polymerase I Promoter Clearance BioSystems: REACTOME 1.154E-3 4.397E-3 2.379E-2
1.443E-1
 2 111
33 1269530 Signaling by NOTCH BioSystems: REACTOME 1.196E-3 4.397E-3 2.379E-2
1.495E-1
 2 113
34 1269657 RNA Polymerase I Transcription BioSystems: REACTOME 1.196E-3 4.397E-3 2.379E-2
1.495E-1
 2 113
35 946598 Thyroid hormone signaling pathway BioSystems: KEGG 1.260E-3 4.499E-3 2.434E-2
1.575E-1
 2 116
36 83054 Cell cycle BioSystems: KEGG 1.438E-3 4.882E-3 2.641E-2
1.797E-1
 2 124
37 137965 a4b1 and a4b7 Integrin signaling BioSystems: Pathway Interaction Database 1.445E-3 4.882E-3 2.641E-2
1.807E-1
 1 3
38 1269656 RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription BioSystems: REACTOME 2.123E-3 6.984E-3 3.778E-2
2.654E-1
 2 151
39 1269377 Factors involved in megakaryocyte development and platelet production BioSystems: REACTOME 2.293E-3 7.348E-3 3.975E-2
2.866E-1
 2 157
40 1383076 Regulation of TP53 Activity BioSystems: REACTOME 2.439E-3 7.622E-3 4.123E-2
3.049E-1
 2 162
41 585563 Alcoholism BioSystems: KEGG 3.001E-3 9.150E-3 4.950E-2
3.752E-1
 2 180
42 83100 Huntington's disease BioSystems: KEGG 3.442E-3 1.024E-2
5.542E-2
4.303E-1
 2 193
43 658418 Viral carcinogenesis BioSystems: KEGG 3.728E-3 1.080E-2
5.841E-2
4.660E-1
 2 201
44 585562 Epstein-Barr virus infection BioSystems: KEGG 3.801E-3 1.080E-2
5.841E-2
4.751E-1
 2 203
45 138029 Sumoylation by RanBP2 regulates transcriptional repression BioSystems: Pathway Interaction Database 5.291E-3 1.470E-2
7.950E-2
6.613E-1
 1 11
46 1269598 Repression of WNT target genes BioSystems: REACTOME 5.770E-3 1.535E-2
8.302E-2
7.213E-1
 1 12
47 M13404 Control of Gene Expression by Vitamin D Receptor MSigDB C2 BIOCARTA (v6.0) 5.770E-3 1.535E-2
8.302E-2
7.213E-1
 1 12
48 M8516 Multi-step Regulation of Transcription by Pitx2 MSigDB C2 BIOCARTA (v6.0) 7.209E-3 1.877E-2
1.016E-1
9.011E-1
 1 15
49 PW:0000718 p53 signaling pathway Pathway Ontology 7.688E-3 1.961E-2
1.061E-1
9.610E-1
 1 16
50 852705 MicroRNAs in cancer BioSystems: KEGG 8.089E-3 2.022E-2
1.094E-1
1.000E0
 2 299
Show 45 more annotations

8: Pubmed [Display Chart] 7 input genes in category / 2915 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 22333916 Epigenetic silencing of myogenic gene program by Myb-binding protein 1a suppresses myogenesis. Pubmed 3.769E-11 5.493E-8 4.700E-7 1.099E-7 3 5
2 10581039 Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation. Pubmed 3.769E-11 5.493E-8 4.700E-7 1.099E-7 3 5
3 21685935 EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin. Pubmed 7.538E-11 7.324E-8 6.266E-7 2.197E-7 3 6
4 22439931 Deconstruction of the SS18-SSX fusion oncoprotein complex: insights into disease etiology and therapeutics. Pubmed 6.216E-10 4.530E-7 3.875E-6 1.812E-6 3 11
5 26864203 Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM. Pubmed 2.052E-8 1.499E-6 1.282E-5 5.981E-5 3 33
6 28139683 Delaying histone deacetylase response to injury accelerates conversion into repair Schwann cells and nerve regeneration. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
7 19416910 Genetic dissection of histone deacetylase requirement in tumor cells. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
8 25688158 Selective Inhibition of HDAC1 and HDAC2 as a Potential Therapeutic Option for B-ALL. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
9 21423190 HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
10 15016876 The binding of histone deacetylases and the integrity of zinc finger-like motifs of the E7 protein are essential for the life cycle of human papillomavirus type 31. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
11 19531758 Expression and function of histone deacetylases in rheumatoid arthritis synovial fibroblasts. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
12 19740981 Histone deacetylases 1 and 2 are phosphorylated at novel sites during varicella-zoster virus infection. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
13 23280436 Dynamic distribution of HDAC1 and HDAC2 during mitosis: association with F-actin. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
14 23251689 Class I and class II histone deacetylases are potential therapeutic targets for treating pancreatic cancer. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
15 20802485 Human HDAC1 and HDAC2 function in the DNA-damage response to promote DNA nonhomologous end-joining. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
16 25648995 HDAC1 and HDAC2 collectively regulate intestinal stem cell homeostasis. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
17 15297431 Class I histone deacetylase-selective novel synthetic inhibitors potently inhibit human tumor proliferation. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
18 19822520 Trans-regulation of histone deacetylase activities through acetylation. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
19 24449838 A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
20 21292776 Deciphering the molecular and biologic processes that mediate histone deacetylase inhibitor-induced thrombocytopenia. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
21 26352599 HDAC1 and HDAC2 independently predict mortality in hepatocellular carcinoma by a competing risk regression model in a Southeast Asian population. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
22 26174178 Distinct Roles for Intestinal Epithelial Cell-Specific Hdac1 and Hdac2 in the Regulation of Murine Intestinal Homeostasis. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
23 22344732 HDAC1 and HDAC2 are differentially expressed in endometriosis. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
24 22307625 Histone deacetylases 1 and 2 regulate autophagy flux and skeletal muscle homeostasis in mice. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
25 22037263 Histone deacetylase 1 and 2 in mesenchymal tumors. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
26 21725353 Endogenous modulators and pharmacological inhibitors of histone deacetylases in cancer therapy. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
27 18408217 Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
28 23516383 Histone deacetylase 2 (HDAC2) regulates chromosome segregation and kinetochore function via H4K16 deacetylation during oocyte maturation in mouse. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
29 19553468 Histone deacetylases 1 and 2 form a developmental switch that controls excitatory synapse maturation and function. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
30 10904264 NuRD and SIN3 histone deacetylase complexes in development. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
31 19561124 A novel domain in histone deacetylase 1 and 2 mediates repression of cartilage-specific genes in human chondrocytes. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
32 22156779 Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
33 24525021 The acetylome regulators Hdac1 and Hdac2 differently modulate intestinal epithelial cell dependent homeostatic responses in experimental colitis. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
34 23616648 A conserved gammaherpesvirus protein kinase targets histone deacetylases 1 and 2 to facilitate viral replication in primary macrophages. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
35 19412887 Histone deacetylase HDAC1/HDAC2-controlled embryonic development and cell differentiation. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
36 25942572 Histone deacetylases 1 and 2 regulate DNA replication and DNA repair: potential targets for genome stability-mechanism-based therapeutics for a subset of cancers. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
37 20398369 HDAC2 attenuates TRAIL-induced apoptosis of pancreatic cancer cells. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
38 28579617 HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
39 26116233 Histone hypoacetylation and increased histone deacetylases in peripheral blood mononuclear cells from patients with Graves' disease. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
40 11287668 HDA2 and HDA3 are related proteins that interact with and are essential for the activity of the yeast histone deacetylase HDA1. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
41 24958871 Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
42 23792463 Disrupted ectodermal organ morphogenesis in mice with a conditional histone deacetylase 1, 2 deletion in the epidermis. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
43 23436026 The expression of HDAC1 and HDAC2 during cerebellar cortical development. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
44 25270209 [Regulatory effect of ginsenoside Rh2 on HDAC1/2 activity and cyclin in human erythroleukemia K562 cells]. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
45 23287868 Histone deacetylase 1 and 2 are essential for normal T-cell development and genomic stability in mice. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
46 27644248 Hypoxia-induced NIPP1 activation enhances metastatic potential and predicts poor prognosis in hepatocellular carcinoma. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
47 20585871 Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
48 24335310 Primary macrophages rely on histone deacetylase 1 and 2 expression to induce type I interferon in response to gammaherpesvirus infection. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
49 11919195 Phosphatase inhibition leads to histone deacetylases 1 and 2 phosphorylation and disruption of corepressor interactions. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
50 23575838 Loss of histone deacetylase 2 improves working memory and accelerates extinction learning. Pubmed 2.879E-8 1.499E-6 1.282E-5 8.393E-5 2 2
Show 45 more annotations

9: Interaction [Display Chart] 7 input genes in category / 974 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:CRY1 CRY1 interactions 1.524E-7 6.699E-5 4.997E-4 1.485E-4 4 146
2 int:DEC1 DEC1 interactions 1.869E-7 6.699E-5 4.997E-4 1.820E-4 3 32
3 int:SSX2 SSX2 interactions 2.464E-7 6.699E-5 4.997E-4 2.400E-4 3 35
4 int:KDM5A KDM5A interactions 2.925E-7 6.699E-5 4.997E-4 2.849E-4 3 37
5 int:CDYL CDYL interactions 3.439E-7 6.699E-5 4.997E-4 3.349E-4 3 39
6 int:RUNX3 RUNX3 interactions 4.640E-7 7.533E-5 5.619E-4 4.520E-4 3 43
7 int:SS18 SS18 interactions 5.705E-7 7.938E-5 5.921E-4 5.557E-4 3 46
8 int:PPP1R8 PPP1R8 interactions 6.921E-7 8.426E-5 6.285E-4 6.741E-4 3 49
9 int:EHMT1 EHMT1 interactions 9.309E-7 9.832E-5 7.334E-4 9.067E-4 3 54
10 int:RBBP4 RBBP4 interactions 1.009E-6 9.832E-5 7.334E-4 9.832E-4 4 234
11 int:C22orf31 C22orf31 interactions 1.339E-6 1.186E-4 8.847E-4 1.305E-3 2 5
12 int:OVOL1 OVOL1 interactions 2.009E-6 1.505E-4 1.123E-3 1.957E-3 2 6
13 int:SNAI3 SNAI3 interactions 2.009E-6 1.505E-4 1.123E-3 1.957E-3 2 6
14 int:E2F6 E2F6 interactions 2.425E-6 1.629E-4 1.215E-3 2.362E-3 3 74
15 int:WIZ WIZ interactions 2.629E-6 1.629E-4 1.215E-3 2.560E-3 3 76
16 int:MIER3 MIER3 interactions 2.812E-6 1.629E-4 1.215E-3 2.739E-3 2 7
17 int:SNAI1 SNAI1 interactions 2.844E-6 1.629E-4 1.215E-3 2.770E-3 3 78
18 int:DNMT3B DNMT3B interactions 3.688E-6 1.995E-4 1.488E-3 3.592E-3 3 85
19 int:ARID1A ARID1A interactions 3.956E-6 2.028E-4 1.513E-3 3.853E-3 3 87
20 int:EZH2 EZH2 interactions 4.165E-6 2.028E-4 1.513E-3 4.057E-3 4 334
21 int:SUZ12 SUZ12 interactions 5.306E-6 2.461E-4 1.836E-3 5.168E-3 4 355
22 int:H2AFY H2AFY interactions 5.842E-6 2.586E-4 1.929E-3 5.690E-3 3 99
23 int:HDAC2 HDAC2 interactions 6.806E-6 2.867E-4 2.139E-3 6.629E-3 4 378
24 int:PRDM4 PRDM4 interactions 7.359E-6 2.867E-4 2.139E-3 7.167E-3 2 11
25 int:MBD3L2 MBD3L2 interactions 7.359E-6 2.867E-4 2.139E-3 7.167E-3 2 11
26 int:DNMT1 DNMT1 interactions 8.700E-6 3.185E-4 2.376E-3 8.474E-3 3 113
27 int:PRDM6 PRDM6 interactions 8.829E-6 3.185E-4 2.376E-3 8.599E-3 2 12
28 int:NACC2 NACC2 interactions 1.217E-5 4.087E-4 3.049E-3 1.185E-2 2 14
29 int:HOXA11 HOXA11 interactions 1.217E-5 4.087E-4 3.049E-3 1.185E-2 2 14
30 int:SMARCA2 SMARCA2 interactions 1.325E-5 4.303E-4 3.210E-3 1.291E-2 3 130
31 int:TET1 TET1 interactions 1.404E-5 4.411E-4 3.290E-3 1.367E-2 2 15
32 int:GTF2I GTF2I interactions 1.551E-5 4.595E-4 3.428E-3 1.511E-2 3 137
33 int:ESCO1 ESCO1 interactions 1.604E-5 4.595E-4 3.428E-3 1.562E-2 2 16
34 int:HR HR interactions 1.604E-5 4.595E-4 3.428E-3 1.562E-2 2 16
35 int:ZBTB16 ZBTB16 interactions 1.727E-5 4.754E-4 3.546E-3 1.682E-2 3 142
36 int:GFI1 GFI1 interactions 1.818E-5 4.754E-4 3.546E-3 1.770E-2 2 17
37 int:PADI4 PADI4 interactions 1.818E-5 4.754E-4 3.546E-3 1.770E-2 2 17
38 int:YY1 YY1 interactions 1.877E-5 4.754E-4 3.546E-3 1.828E-2 3 146
39 int:RCOR2 RCOR2 interactions 2.044E-5 4.754E-4 3.546E-3 1.991E-2 2 18
40 int:IFRD1 IFRD1 interactions 2.044E-5 4.754E-4 3.546E-3 1.991E-2 2 18
41 int:SMARCA5 SMARCA5 interactions 2.077E-5 4.754E-4 3.546E-3 2.023E-2 3 151
42 int:SETDB1 SETDB1 interactions 2.077E-5 4.754E-4 3.546E-3 2.023E-2 3 151
43 int:RREB1 RREB1 interactions 2.284E-5 4.754E-4 3.546E-3 2.225E-2 2 19
44 int:PDX1 PDX1 interactions 2.284E-5 4.754E-4 3.546E-3 2.225E-2 2 19
45 int:ZFPM1 ZFPM1 interactions 2.284E-5 4.754E-4 3.546E-3 2.225E-2 2 19
46 int:EHMT2 EHMT2 interactions 2.469E-5 4.754E-4 3.546E-3 2.405E-2 3 160
47 int:ZFPM2 ZFPM2 interactions 2.538E-5 4.754E-4 3.546E-3 2.472E-2 2 20
48 int:ESCO2 ESCO2 interactions 2.538E-5 4.754E-4 3.546E-3 2.472E-2 2 20
49 int:SAP30L SAP30L interactions 2.538E-5 4.754E-4 3.546E-3 2.472E-2 2 20
50 int:IKZF2 IKZF2 interactions 2.538E-5 4.754E-4 3.546E-3 2.472E-2 2 20
Show 45 more annotations

10: Cytoband [Display Chart] 7 input genes in category / 7 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 7q35-q36 7q35-q36 1.009E-3 4.239E-3 1.099E-2 7.066E-3 1 5
2 8q11 8q11 1.211E-3 4.239E-3 1.099E-2 8.478E-3 1 6
3 11q14.2 11q14.2 3.227E-3 7.530E-3 1.952E-2 2.259E-2 1 16
4 1p34 1p34 6.445E-3 9.586E-3 2.485E-2 4.512E-2 1 32
5 1p35.3 1p35.3 6.847E-3 9.586E-3 2.485E-2 4.793E-2 1 34
6 12q13.13 12q13.13 1.405E-2 1.639E-2 4.251E-2
9.837E-2
 1 70
7 6q21 6q21 2.062E-2 2.062E-2
5.346E-2
1.443E-1
 1 103
Show 2 more annotations

11: Transcription Factor Binding Site [Display Chart] 5 input genes in category / 48 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$E2F Q3 V$E2F Q3 3.149E-3 1.911E-2
8.519E-2
1.511E-1
 2 177
2 V$E2F1 Q4 01 V$E2F1 Q4 01 3.290E-3 1.911E-2
8.519E-2
1.579E-1
 2 181
3 V$E2F Q6 V$E2F Q6 3.326E-3 1.911E-2
8.519E-2
1.596E-1
 2 182
4 V$E2F Q4 V$E2F Q4 3.398E-3 1.911E-2
8.519E-2
1.631E-1
 2 184
5 V$E2F1DP1RB 01 V$E2F1DP1RB 01 3.398E-3 1.911E-2
8.519E-2
1.631E-1
 2 184
6 V$E2F Q4 01 V$E2F Q4 01 3.435E-3 1.911E-2
8.519E-2
1.649E-1
 2 185
7 V$E2F Q3 01 V$E2F Q3 01 3.471E-3 1.911E-2
8.519E-2
1.666E-1
 2 186
8 V$E2F1 Q4 V$E2F1 Q4 3.582E-3 1.911E-2
8.519E-2
1.720E-1
 2 189
9 V$E2F1 Q6 01 V$E2F1 Q6 01 3.582E-3 1.911E-2
8.519E-2
1.720E-1
 2 189
Show 4 more annotations

12: Gene Family [Display Chart] 5 input genes in category / 9 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 989 Histone deacetylases, class I genenames.org 3.625E-7 3.262E-6 9.228E-6 3.262E-6 2 4
2 1306 EMSY complex|SIN3 histone deacetylase complex genenames.org 2.174E-6 8.963E-6 2.536E-5 1.956E-5 2 9
3 1305 Histone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex genenames.org 3.983E-6 8.963E-6 2.536E-5 3.585E-5 2 12
4 1243 EMSY complex genenames.org 3.983E-6 8.963E-6 2.536E-5 3.585E-5 2 12
5 1347 Lysine methyltransferases|Myb/SANT domain containing|Polycomb repressive complex 2 genenames.org 1.648E-3 2.966E-3 8.392E-3 1.483E-2 1 6
6 1159 Integrin beta subunits genenames.org 2.471E-3 3.707E-3 1.049E-2 2.224E-2 1 9
7 487 Lysine methyltransferases|RNA binding motif containing genenames.org 9.310E-3 1.197E-2 3.386E-2
8.379E-2
 1 34
8 532 GATA zinc finger domain containing|Myb/SANT domain containing genenames.org 1.448E-2 1.629E-2 4.609E-2
1.303E-1
 1 53
9 694 Protein phosphatase 1 regulatory subunits genenames.org 4.877E-2 4.877E-2
1.380E-1
4.389E-1
 1 181
Show 4 more annotations

13: Coexpression [Display Chart] 7 input genes in category / 1017 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M2114 Set 'Proliferation Cluster': genes defined in human breast tumor expression data. MSigDB C2: CGP Curated Gene Sets (v6.0) 8.632E-6 2.760E-3 2.070E-2 8.779E-3 3 147
2 M6747 Genes down-regulated in cells from Flt3L Melanom injected mice: 33D1+ versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.311E-5 2.760E-3 2.070E-2 1.334E-2 3 169
3 M8928 Genes down-regulated in CD4 [GeneID=920] naïve versus Th17 enriched. MSigDB C7: Immunologic Signatures (v6.0) 1.431E-5 2.760E-3 2.070E-2 1.455E-2 3 174
4 M6756 Genes up-regulated in splenic CD 33D1+ dendritic cells versus CD4 [GeneID=920] T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.610E-5 2.760E-3 2.070E-2 1.638E-2 3 181
5 16121216-TableS1 Human Leukemia Bradbury05 23genes AssociatedProteinsPMBC GeneSigDB 1.643E-5 2.760E-3 2.070E-2 1.671E-2 2 21
6 16121216-TableS2 Human Leukemia Bradbury05 23genes RelatedProteinsMC GeneSigDB 1.643E-5 2.760E-3 2.070E-2 1.671E-2 2 21
7 M3027 Genes up-regulated in comparison of naive versus memory CD8 T cells (day 40+ following LCMV-Armstrong infection). MSigDB C7: Immunologic Signatures (v6.0) 2.139E-5 2.760E-3 2.070E-2 2.175E-2 3 199
8 M6014 Genes down-regulated in dendritic cells: CIITA [GeneID=4261] knockout versus I ab-/- mice. MSigDB C7: Immunologic Signatures (v6.0) 2.171E-5 2.760E-3 2.070E-2 2.208E-2 3 200
9 M11333 Oxidative stress genes down-regulated in ARPE-19 cells (retinal pigmented epithelium) in response to tert-butyl hydroperoxide (tBH) and H2O2 [PubChem=6410;784]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.919E-5 5.558E-3 4.170E-2
5.003E-2
 2 36
10 17699800-Table1 Human Lung Joo07 54genes GeneSigDB 1.114E-4 1.133E-2
8.503E-2
1.133E-1
 2 54
11 16699793-Table2 Human pancreas Miyake06 72genes GeneSigDB 1.930E-4 1.755E-2
1.317E-1
1.963E-1
 2 71
12 19336569-SuppTable3 Human Breast Zhang09 81genes GeneSigDB 2.154E-4 1.755E-2
1.317E-1
2.191E-1
 2 75
13 19096012-TableS2 Human Viral Chetaille09 501genes GeneSigDB 2.244E-4 1.755E-2
1.317E-1
2.282E-1
 3 439
14 16618758-SuppTable1 Mouse StemCell Lien06 91genes GeneSigDB 2.576E-4 1.871E-2
1.404E-1
2.620E-1
 2 82
15 M14665 Genes up-regulated in lymphoblastoid cells from the European population compared to those from the Asian population. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.883E-4 1.955E-2
1.466E-1
2.932E-1
 3 478
16 M14079 Breast cancer compendium: 100 transcription regulators showing most correlated expression with the 9 'embryonic stem cell' transcription factors that are preferentially and coordinately overexpressed in the high-grade, ER-negative breast cancer tumors. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.829E-4 2.337E-2
1.753E-1
3.894E-1
 2 100
17 M15356 Genes constituting the LIT-Int network of proteins interacting with breast cancer reference proteins BRCA1, BRCA2, ATM, and CHEK2 [GeneID=672;675;472;11200]; the interactions were manually curated from the literature. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.906E-4 2.337E-2
1.753E-1
3.973E-1
 2 101
18 M12804 Genes up-regulated in P14 nerves of transgenic mice having hypomorhic (reduced function) allele of EGR2 [GeneID=1959]. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.465E-4 2.523E-2
1.893E-1
4.541E-1
 2 108
19 18689800-TableS6 Human EmbryonicStemCell Thomas08 113genes GeneSigDB 4.715E-4 2.524E-2
1.894E-1
4.796E-1
 2 111
20 M3000 Genes up-regulated in B lymphocytes with ZFX [GeneID=7543] knockout: control versus stimulated by anti-IgM for 2h. MSigDB C7: Immunologic Signatures (v6.0) 1.012E-3 2.834E-2
2.126E-1
1.000E0
 2 163
21 M17193 Down-regulated genes distinguishing in multiple myeloma (MM) samples with lower expression of TACI [GeneID=23495]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.126E-3 2.834E-2
2.126E-1
1.000E0
 2 172
22 M7103 Genes up-regulated in centroblasts versus centrocytes. MSigDB C7: Immunologic Signatures (v6.0) 1.152E-3 2.834E-2
2.126E-1
1.000E0
 2 174
23 M3268 Top 200 marker genes up-regulated in the 'proliferation' subclass of hepatocellular carcinoma (HCC); characterized by increased proliferation, high levels of serum AFP [GeneID=174], and chromosomal instability. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.205E-3 2.834E-2
2.126E-1
1.000E0
 2 178
24 M8126 Genes up-regulated in IL10 [GeneID=3586] knockout macrophages stimulated by LPS versus those also stimulated by IL10 [GeneID=3586]. MSigDB C7: Immunologic Signatures (v6.0) 1.246E-3 2.834E-2
2.126E-1
1.000E0
 2 181
25 18519693-Table1 Human StemCell Mishra08 289genes GeneSigDB 1.259E-3 2.834E-2
2.126E-1
1.000E0
 2 182
26 M1913 Genes down-regulated in neural stem cells (NSC) at 36 h after cre-lox knockout of TLX (NR2E1) [GeneID=7101]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.301E-3 2.834E-2
2.126E-1
1.000E0
 2 185
27 M2652 Genes down-regulated in MCF-7 cells (breast cancer) over-expressing CCND1 [Gene ID=595] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.385E-3 2.834E-2
2.126E-1
1.000E0
 2 191
28 M5136 Genes up-regulated in comparison of peripheral blood mononuclear cells (PBMC) from healthy donors versus PBMCs from infanct with acute RSV infection. MSigDB C7: Immunologic Signatures (v6.0) 1.488E-3 2.834E-2
2.126E-1
1.000E0
 2 198
29 M4142 Genes down-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 0.5 h versus those stimulated with Gardiquimod (TLR7 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.834E-2
2.126E-1
1.000E0
 2 199
30 M3192 Genes up-regulated in comparison of IgD- peripheral blood B cells versus dark zone germinal center B cells. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.834E-2
2.126E-1
1.000E0
 2 199
31 M5142 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from infancts with acute RSV infection versus PBMCs from infants with acute influenza infection. MSigDB C7: Immunologic Signatures (v6.0) 1.502E-3 2.834E-2
2.126E-1
1.000E0
 2 199
32 M4929 Genes down-regulated in comparison of peripheral blood mononuclear cells (PBMC) from TIV influenza vaccinee pre-vaccination versus those at day 3 post-vaccination. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
33 M3945 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
34 M8277 Genes up-regulated in B lymphocytes stimulated by anti-IgM for 8h: wildtype versus NFATC1 [GeneID=4772] knockout. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
35 M5862 Genes up-regulated in comparison of monocytes treated with 1 ng/ml LPS (TLR4 agonist) versus monocytes treated with anti-TREM1 [GeneID=54210] and 5000 ng/ml LPS (TLR4 agonist). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
36 M6896 Genes down-regulated in macrophages with IL10 [GeneID=3586] knockout in response to 10 min treatment by: LPS versus LPS and IL10 [GeneID=3586]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
37 M3509 Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 360 min. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
38 M8075 Genes up-regulated in thymic implants from fetal liver versus those from fetal bone marrow. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
39 M5833 Genes up-regulated in comparison of effector CD8 T cells versus exhausted CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
40 M7289 Genes down-regulated in lymphocytes treated with medium for 24h: T conv versus T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
41 M4523 Genes down-regulated in comparison of naive CD4 [GeneID=920] T cells versus stimulated CD4 [GeneID=920] Th1 cells at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
42 M3840 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 12 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 12 h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
43 M5831 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
44 M6930 Genes up-regulated in B lymphocytes: anti IgM versus PL2-3 (Chromatin IC). MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
45 M5925 Genes encoding cell cycle related targets of E2F transcription factors. MSigDB H: Hallmark Gene Sets (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
46 M8805 Genes down-regulated in Foxp3-ires-GFP T reg (FOXP3+ [GeneID=50943]): B6 versus NOD background. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
47 M3038 Genes up-regulated in comparison of naive CD8 T cells versus memory CD8 T cells. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
48 M7162 Genes down-regulated in CD4 [GeneID=920] T cells treated with HDAC inhibitors: 2h versus 12h. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
49 M6157 Genes down-regulated in monocyte-derived macrophages: no priming versus primed by IFNG [GeneID=3458]. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
50 M3480 Genes up-regulated in CD4 [GeneID=920] T cells from cord blood versus those from adult blood. MSigDB C7: Immunologic Signatures (v6.0) 1.517E-3 2.834E-2
2.126E-1
1.000E0
 2 200
Show 45 more annotations

14: Coexpression Atlas [Display Chart] 7 input genes in category / 415 annotations before applied cutoff / 21829 genes in category

No results to display

15: Computational [Display Chart] 6 input genes in category / 102 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M14843 MODULE 98 Genes in the cancer module 98. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.262E-5 3.327E-3 1.733E-2 3.327E-3 4 393
2 M4550 MODULE 252 TFs and nuclear. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.467E-4 1.258E-2
6.551E-2
 2.516E-2 3 237
3 M582 MODULE 57 Genes in the cancer module 57. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.521E-4 1.298E-2
6.761E-2
 4.611E-2 2 56
4 M17658 MODULE 198 Genes in the cancer module 198. MSigDb: C4 - CM: Cancer Modules (v6.0) 5.092E-4 1.298E-2
6.761E-2
5.193E-2
 3 303
5 M15846 MORF PAPSS1 Neighborhood of PAPSS1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.465E-3 2.988E-2
1.556E-1
1.494E-1
 2 101
6 M3928 GNF2 DAP3 Neighborhood of DAP3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.027E-3 3.446E-2
1.794E-1
2.067E-1
 2 119
7 M5305 MODULE 361 B lymphoma expression clusters. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.199E-3 3.935E-2
2.049E-1
3.263E-1
 2 150
8 M13275 MODULE 301 Genes in the cancer module 301. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.588E-3 3.935E-2
2.049E-1
3.659E-1
 2 159
9 M18610 MORF PPP1CC Neighborhood of PPP1CC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.812E-3 3.935E-2
2.049E-1
3.889E-1
 2 164
10 M7201 MODULE 238 Genes in the cancer module 238. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.858E-3 3.935E-2
2.049E-1
3.935E-1
 2 165
11 M4092 MODULE 197 Genes in the cancer module 197. MSigDb: C4 - CM: Cancer Modules (v6.0) 4.282E-3 3.970E-2
2.067E-1
4.367E-1
 2 174
Show 6 more annotations

16: MicroRNA [Display Chart] 7 input genes in category / 170 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-874-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 2.347E-5 3.989E-3 2.280E-2 3.989E-3 2 77
2 CTTTGTA,MIR-524:MSigDB CTTTGTA,MIR-524:MSigDB MSigDB 6.590E-4 3.064E-2
1.752E-1
1.120E-1
 2 409
3 hsa-miR-4281:mirSVR lowEffct hsa-miR-4281:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 6.622E-4 3.064E-2
1.752E-1
1.126E-1
 2 410
4 hsa-miR-1915*:mirSVR highEffct hsa-miR-1915*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.354E-4 3.064E-2
1.752E-1
1.420E-1
 2 461
5 hsa-miR-219-5p:mirSVR highEffct hsa-miR-219-5p:mirSVR conserved highEffect-0.5 MicroRNA.org 9.013E-4 3.064E-2
1.752E-1
1.532E-1
 2 479
6 hsa-miR-6500-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.835E-3 4.699E-2
2.686E-1
8.220E-1
 1 50
7 hsa-miR-4633-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.835E-3 4.699E-2
2.686E-1
8.220E-1
 1 50
8 hsa-miR-6874-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 4.835E-3 4.699E-2
2.686E-1
8.220E-1
 1 50
9 hsa-miR-126-3p:Functional MTI Functional MTI miRTarbase 5.510E-3 4.699E-2
2.686E-1
9.368E-1
 1 57
10 hsa-miR-101-5p:Functional MTI Functional MTI miRTarbase 6.571E-3 4.699E-2
2.686E-1
1.000E0
 1 68
11 hsa-miR-217:Functional MTI Functional MTI miRTarbase 7.726E-3 4.699E-2
2.686E-1
1.000E0
 1 80
12 hsa-miR-127-3p:mirSVR highEffct hsa-miR-127-3p:mirSVR conserved highEffect-0.5 MicroRNA.org 7.823E-3 4.699E-2
2.686E-1
1.000E0
 1 81
13 hsa-miR-371-3p:mirSVR highEffct hsa-miR-371-3p:mirSVR nonconserved highEffect-0.5 MicroRNA.org 8.015E-3 4.699E-2
2.686E-1
1.000E0
 1 83
14 hsa-miR-1283:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.496E-3 4.699E-2
2.686E-1
1.000E0
 1 88
15 hsa-miR-4327:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 9.266E-3 4.699E-2
2.686E-1
1.000E0
 1 96
16 ATTACAT,MIR-380-3P:MSigDB ATTACAT,MIR-380-3P:MSigDB MSigDB 9.554E-3 4.699E-2
2.686E-1
1.000E0
 1 99
17 hsa-miR-106b*:mirSVR highEffct hsa-miR-106b*:mirSVR nonconserved highEffect-0.5 MicroRNA.org 9.842E-3 4.699E-2
2.686E-1
1.000E0
 1 102
18 hsa-miR-708-5p:Functional MTI Functional MTI miRTarbase 1.003E-2 4.699E-2
2.686E-1
1.000E0
 1 104
19 ATGCAGT,MIR-217:MSigDB ATGCAGT,MIR-217:MSigDB MSigDB 1.003E-2 4.699E-2
2.686E-1
1.000E0
 1 104
20 hsa-miR-139-5p:Functional MTI Functional MTI miRTarbase 1.013E-2 4.699E-2
2.686E-1
1.000E0
 1 105
21 hsa-miR-6865-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.023E-2 4.699E-2
2.686E-1
1.000E0
 1 106
22 hsa-miR-320c:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.042E-2 4.699E-2
2.686E-1
1.000E0
 1 108
23 hsa-miR-138-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.205E-2 4.699E-2
2.686E-1
1.000E0
 1 125
24 hsa-miR-1258:PITA hsa-miR-1258:PITA TOP PITA 1.253E-2 4.699E-2
2.686E-1
1.000E0
 1 130
25 hsa-miR-1273c:mirSVR highEffct hsa-miR-1273c:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.272E-2 4.699E-2
2.686E-1
1.000E0
 1 132
26 hsa-miR-3653-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.272E-2 4.699E-2
2.686E-1
1.000E0
 1 132
27 hsa-miR-340-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.272E-2 4.699E-2
2.686E-1
1.000E0
 1 132
28 hsa-miR-505-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.291E-2 4.699E-2
2.686E-1
1.000E0
 1 134
29 hsa-miR-1292-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.310E-2 4.699E-2
2.686E-1
1.000E0
 1 136
30 hsa-miR-449b-5p:Functional MTI Functional MTI miRTarbase 1.349E-2 4.699E-2
2.686E-1
1.000E0
 1 140
31 hsa-miR-602:mirSVR highEffct hsa-miR-602:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.368E-2 4.699E-2
2.686E-1
1.000E0
 1 142
32 hsa-miR-3679-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.425E-2 4.699E-2
2.686E-1
1.000E0
 1 148
33 hsa-miR-137:Non-Functional MTI Non-Functional MTI miRTarbase 1.425E-2 4.699E-2
2.686E-1
1.000E0
 1 148
34 hsa-miR-200a-3p:Functional MTI Functional MTI miRTarbase 1.445E-2 4.699E-2
2.686E-1
1.000E0
 1 150
35 hsa-miR-429:Functional MTI Functional MTI miRTarbase 1.454E-2 4.699E-2
2.686E-1
1.000E0
 1 151
36 hsa-miR-671-5p:Functional MTI Functional MTI miRTarbase 1.511E-2 4.699E-2
2.686E-1
1.000E0
 1 157
37 hsa-miR-449a:Functional MTI Functional MTI miRTarbase 1.550E-2 4.699E-2
2.686E-1
1.000E0
 1 161
38 hsa-miR-1260a:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.559E-2 4.699E-2
2.686E-1
1.000E0
 1 162
39 hsa-miR-1260:PITA hsa-miR-1260:PITA TOP PITA 1.588E-2 4.699E-2
2.686E-1
1.000E0
 1 165
40 hsa-miR-490-3p:TargetScan hsa-miR-490-3p TargetScan 1.588E-2 4.699E-2
2.686E-1
1.000E0
 1 165
41 hsa-miR-199a-5p:Non-Functional MTI Non-Functional MTI miRTarbase 1.598E-2 4.699E-2
2.686E-1
1.000E0
 1 166
42 hsa-miR-383-5p.2:TargetScan hsa-miR-383-5p.2 TargetScan 1.607E-2 4.699E-2
2.686E-1
1.000E0
 1 167
43 hsa-miR-651:PITA hsa-miR-651:PITA TOP PITA 1.626E-2 4.699E-2
2.686E-1
1.000E0
 1 169
44 hsa-miR-544a:TargetScan hsa-miR-544a TargetScan 1.712E-2 4.699E-2
2.686E-1
1.000E0
 1 178
45 hsa-miR-200b-3p:Functional MTI Functional MTI miRTarbase 1.789E-2 4.699E-2
2.686E-1
1.000E0
 1 186
46 hsa-miR-1273:mirSVR highEffct hsa-miR-1273:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.884E-2 4.699E-2
2.686E-1
1.000E0
 1 196
47 hsa-miR-630:PITA hsa-miR-630:PITA TOP PITA 1.912E-2 4.699E-2
2.686E-1
1.000E0
 1 199
48 hsa-miR-7851-3p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.912E-2 4.699E-2
2.686E-1
1.000E0
 1 199
49 CACCAGC,MIR-138:MSigDB CACCAGC,MIR-138:MSigDB MSigDB 1.922E-2 4.699E-2
2.686E-1
1.000E0
 1 200
50 hsa-miR-517a:mirSVR highEffct hsa-miR-517a:mirSVR nonconserved highEffect-0.5 MicroRNA.org 1.932E-2 4.699E-2
2.686E-1
1.000E0
 1 201
Show 45 more annotations

17: Drug [Display Chart] 7 input genes in category / 1065 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 DB02546 Vorinostat Drug Bank 8.047E-7 8.570E-4 6.469E-3 8.570E-4 2 5
2 ctd:C055305 ginsenoside Rh2 CTD 2.895E-6 1.083E-3 8.174E-3 3.084E-3 2 9
3 CID000002746 CI-994 Stitch 3.619E-6 1.083E-3 8.174E-3 3.854E-3 2 10
4 CID000467801 Apicidin Stitch 4.067E-6 1.083E-3 8.174E-3 4.332E-3 3 113
5 CID005474719 AC1NV99J Stitch 9.641E-6 1.625E-3 1.226E-2 1.027E-2 2 16
6 ctd:C472086 polyphenon E CTD 1.093E-5 1.625E-3 1.226E-2 1.164E-2 2 17
7 CID000038078 Rodeo Stitch 1.093E-5 1.625E-3 1.226E-2 1.164E-2 2 17
8 CID000002992 AC1L1EXH Stitch 1.229E-5 1.625E-3 1.226E-2 1.309E-2 2 18
9 CID000446054 In-G Stitch 1.387E-5 1.625E-3 1.226E-2 1.477E-2 3 170
10 CID000019103 NSC3852 Stitch 1.526E-5 1.625E-3 1.226E-2 1.625E-2 2 20
11 CID000002706 AC1L1EA5 Stitch 2.215E-5 2.136E-3 1.613E-2 2.359E-2 2 24
12 ctd:C000602704 UF010 compound CTD 2.407E-5 2.136E-3 1.613E-2 2.564E-2 2 25
13 CID000003571 AC1L1G8B Stitch 3.976E-5 3.257E-3 2.459E-2 4.234E-2 2 32
14 CID006857719 AC1OAH4D Stitch 5.047E-5 3.839E-3 2.898E-2
5.375E-2
 2 36
15 ctd:C087123 romidepsin CTD 7.569E-5 5.374E-3 4.057E-2
8.061E-2
 2 44
16 ctd:C031818 enterotoxin B, staphylococcal CTD 1.101E-4 7.330E-3
5.533E-2
1.173E-1
 2 53
17 ctd:D000068876 Fingolimod Hydrochloride CTD 1.186E-4 7.432E-3
5.610E-2
1.263E-1
 2 55
18 CID000121875 trapoxin Stitch 1.320E-4 7.657E-3
5.780E-2
1.406E-1
 2 58
19 CID000177324 SNAG Stitch 1.366E-4 7.657E-3
5.780E-2
1.455E-1
 2 59
20 CID000003121 valproate Stitch 1.533E-4 8.165E-3
6.164E-2
1.633E-1
 3 381
21 CID000000597 cytosine Stitch 2.362E-4 1.198E-2
9.040E-2
2.515E-1
 3 441
22 ctd:C453963 3-(4-benzoyl-1-methyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide CTD 3.065E-4 1.429E-2
1.079E-1
3.264E-1
 1 1
23 ctd:C007262 deoxynivalenol CTD 3.087E-4 1.429E-2
1.079E-1
3.288E-1
 3 483
24 CID000000340 3-methylcatechol Stitch 3.773E-4 1.674E-2
1.264E-1
4.019E-1
 2 98
25 CID000444218 AC1L9FY1 Stitch 4.007E-4 1.707E-2
1.289E-1
4.268E-1
 2 101
26 CID006368594 AC1OC6D1 Stitch 4.248E-4 1.740E-2
1.314E-1
4.524E-1
 2 104
27 ctd:C523184 mocetinostat CTD 4.413E-4 1.741E-2
1.314E-1
4.700E-1
 2 106
28 ctd:C097240 15-deoxy-delta(12,14)-prostaglandin J2 CTD 5.101E-4 1.920E-2
1.449E-1
5.433E-1
 2 114
29 ctd:C016392 3,3'-diindolylmethane CTD 5.281E-4 1.920E-2
1.449E-1
5.624E-1
 2 116
30 CID000029051 NSC24559 Stitch 5.839E-4 1.920E-2
1.449E-1
6.219E-1
 2 122
31 ctd:D010867 Pimelic Acids CTD 6.129E-4 1.920E-2
1.449E-1
6.527E-1
 1 2
32 ctd:C527895 largazole CTD 6.129E-4 1.920E-2
1.449E-1
6.527E-1
 1 2
33 ctd:C557525 SB939 compound CTD 6.129E-4 1.920E-2
1.449E-1
6.527E-1
 1 2
34 ctd:C586265 GSK343 CTD 6.129E-4 1.920E-2
1.449E-1
6.527E-1
 1 2
35 CID000004261 MS-275 Stitch 8.688E-4 2.510E-2
1.895E-1
9.253E-1
 2 149
36 ctd:C067071 trapoxin B CTD 9.192E-4 2.510E-2
1.895E-1
9.789E-1
 1 3
37 CID006430696 7-heptacosene Stitch 9.192E-4 2.510E-2
1.895E-1
9.789E-1
 1 3
38 CID006438632 A9145C Stitch 9.192E-4 2.510E-2
1.895E-1
9.789E-1
 1 3
39 DB00227 Lovastatin Drug Bank 9.192E-4 2.510E-2
1.895E-1
9.789E-1
 1 3
40 CID009547945 DB08184 Stitch 1.089E-3 2.590E-2
1.955E-1
1.000E0
 2 167
41 ctd:C430898 AGN 194204 CTD 1.089E-3 2.590E-2
1.955E-1
1.000E0
 2 167
42 ctd:C001899 triptolide CTD 1.168E-3 2.590E-2
1.955E-1
1.000E0
 2 173
43 ctd:C006963 chlamydocin CTD 1.225E-3 2.590E-2
1.955E-1
1.000E0
 1 4
44 312 DN staurosporine; Down 200; 1uM; MCF7; HG-U133A Broad Institute CMAP Down 1.278E-3 2.590E-2
1.955E-1
1.000E0
 2 181
45 6253 DN Ellipticine [519-23-3]; Down 200; 16.2uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.292E-3 2.590E-2
1.955E-1
1.000E0
 2 182
46 2321 DN Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT HG-U133A Broad Institute CMAP Down 1.320E-3 2.590E-2
1.955E-1
1.000E0
 2 184
47 CID000005350 sulforaphane Stitch 1.392E-3 2.590E-2
1.955E-1
1.000E0
 2 189
48 CID003509873 AC1MQZ6I Stitch 1.406E-3 2.590E-2
1.955E-1
1.000E0
 2 190
49 3100 DN Promethazine hydrochloride [58-33-3]; Down 200; 12.4uM; HL60; HT HG-U133A Broad Institute CMAP Down 1.465E-3 2.590E-2
1.955E-1
1.000E0
 2 194
50 1741 DN Laudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; HL60; HG-U133A Broad Institute CMAP Down 1.465E-3 2.590E-2
1.955E-1
1.000E0
 2 194
Show 45 more annotations

18: Disease [Display Chart] 7 input genes in category / 334 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C2145472 Urothelial Carcinoma DisGeNET BeFree 1.048E-4 9.618E-3
6.146E-2
 3.501E-2 3 238
2 C0206630 Endometrial Stromal Sarcoma DisGeNET Curated 1.176E-4 9.618E-3
6.146E-2
 3.929E-2 2 39
3 C0032584 polyps DisGeNET Curated 1.661E-4 9.618E-3
6.146E-2
5.548E-2
 3 278
4 C0030521 Parathyroid Neoplasms DisGeNET Curated 1.863E-4 9.618E-3
6.146E-2
6.222E-2
 2 49
5 C0030809 Pemphigus Vulgaris DisGeNET BeFree 2.987E-4 9.618E-3
6.146E-2
9.978E-2
 2 62
6 C0281361 Adenocarcinoma of pancreas DisGeNET Curated 3.115E-4 9.618E-3
6.146E-2
1.040E-1
 3 344
7 C3665593 Melanocytic nevus of skin DisGeNET BeFree 3.184E-4 9.618E-3
6.146E-2
1.063E-1
 2 64
8 C0007138 Carcinoma, Transitional Cell DisGeNET Curated 3.503E-4 9.618E-3
6.146E-2
1.170E-1
 3 358
9 C4020835 Flared humerus DisGeNET Curated 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
10 C4020912 Flared humeral metaphysis DisGeNET Curated 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
11 cv:C0265210 Weaver syndrome Clinical Variations 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
12 C1879828 Benign Teratoma DisGeNET BeFree 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
13 C0749794 Upper Extremity Deformities, Congenital DisGeNET Curated 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
14 C4225170 LEUKODYSTROPHY, HYPOMYELINATING, 13 DisGeNET Curated 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
15 C4020918 Dysharmonic bone age DisGeNET Curated 4.320E-4 9.618E-3
6.146E-2
1.443E-1
 1 1
16 C0023452 Leukemia, Lymphocytic, Acute, L1 DisGeNET BeFree 5.598E-4 1.169E-2
7.467E-2
1.870E-1
 3 420
17 C0023470 Myeloid Leukemia DisGeNET Curated 8.473E-4 1.374E-2
8.778E-2
2.830E-1
 3 484
18 C4025674 Flared femoral metaphysis DisGeNET Curated 8.638E-4 1.374E-2
8.778E-2
2.885E-1
 1 2
19 C3272805 Colorectal Adenomatous Polyp DisGeNET BeFree 8.638E-4 1.374E-2
8.778E-2
2.885E-1
 1 2
20 OMIN:277590 WEAVER SYNDROME OMIM 8.638E-4 1.374E-2
8.778E-2
2.885E-1
 1 2
21 C3277753 Deep-set nails DisGeNET Curated 8.638E-4 1.374E-2
8.778E-2
2.885E-1
 1 2
22 C0006012 Borderline Personality Disorder DisGeNET BeFree 9.209E-4 1.398E-2
8.934E-2
3.076E-1
 2 109
23 C0039538 Teratoma DisGeNET Curated 9.893E-4 1.437E-2
9.180E-2
3.304E-1
 2 113
24 C1844690 Limited knee extension DisGeNET Curated 1.295E-3 1.803E-2
1.152E-1
4.327E-1
 1 3
25 C1266025 Traditional Serrated Adenoma DisGeNET BeFree 1.367E-3 1.826E-2
1.167E-1
4.565E-1
 2 133
26 C1856409 Dilation of lateral ventricles DisGeNET Curated 1.727E-3 2.136E-2
1.365E-1
5.768E-1
 1 4
27 C1848514 Short fourth metatarsals DisGeNET Curated 1.727E-3 2.136E-2
1.365E-1
5.768E-1
 1 4
28 C0265210 Weaver syndrome DisGeNET Curated 2.158E-3 2.486E-2
1.588E-1
7.208E-1
 1 5
29 C0423823 Thin nails DisGeNET Curated 2.158E-3 2.486E-2
1.588E-1
7.208E-1
 1 5
30 C0007133 Carcinoma, Papillary DisGeNET BeFree 2.484E-3 2.528E-2
1.616E-1
8.296E-1
 2 180
31 C0006287 Bronchopulmonary Dysplasia DisGeNET Curated 2.511E-3 2.528E-2
1.616E-1
8.387E-1
 2 181
32 C0278952 Nasopharyngeal cancer recurrent DisGeNET BeFree 2.589E-3 2.528E-2
1.616E-1
8.649E-1
 1 6
33 C1835807 Prominent fingertip pads DisGeNET Curated 2.589E-3 2.528E-2
1.616E-1
8.649E-1
 1 6
34 C4023915 Abnormally low-pitched voice DisGeNET Curated 2.589E-3 2.528E-2
1.616E-1
8.649E-1
 1 6
35 C3888194 MIXED LINEAGE LEUKEMIA DisGeNET BeFree 2.649E-3 2.528E-2
1.616E-1
8.849E-1
 2 186
36 C0027962 Melanocytic nevus DisGeNET Curated 2.937E-3 2.681E-2
1.713E-1
9.809E-1
 2 196
37 C0269269 Inversion of nipple (disorder) DisGeNET Curated 3.020E-3 2.681E-2
1.713E-1
1.000E0
 1 7
38 C0729233 Dissecting aneurysm of the thoracic aorta DisGeNET BeFree 3.146E-3 2.681E-2
1.713E-1
1.000E0
 2 203
39 C1860789 Leukemia, Megakaryoblastic, of Down Syndrome DisGeNET Curated 3.451E-3 2.681E-2
1.713E-1
1.000E0
 1 8
40 C1333295 Germinal Center B-Cell-Like Diffuse Large B-Cell Lymphoma DisGeNET BeFree 3.451E-3 2.681E-2
1.713E-1
1.000E0
 1 8
41 C0862824 Stage I Lung Cancer DisGeNET BeFree 3.451E-3 2.681E-2
1.713E-1
1.000E0
 1 8
42 C1860450 Calcaneovalgus deformity DisGeNET Curated 3.451E-3 2.681E-2
1.713E-1
1.000E0
 1 8
43 C0234518 Slurred speech DisGeNET Curated 3.451E-3 2.681E-2
1.713E-1
1.000E0
 1 8
44 C0235782 Gallbladder Carcinoma DisGeNET BeFree 3.554E-3 2.698E-2
1.724E-1
1.000E0
 2 216
45 C1849227 CLEFT CHIN DisGeNET Curated 3.882E-3 2.881E-2
1.841E-1
1.000E0
 1 9
46 C1282496 Metastasis from malignant tumor of prostate DisGeNET BeFree 4.019E-3 2.918E-2
1.865E-1
1.000E0
 2 230
47 C1720771 Testicular Hydrocele DisGeNET Curated 4.312E-3 2.940E-2
1.878E-1
1.000E0
 1 10
48 C0920299 Overriding toe DisGeNET Curated 4.312E-3 2.940E-2
1.878E-1
1.000E0
 1 10
49 C0265286 Dyggve-Melchior-Clausen syndrome DisGeNET Curated 4.312E-3 2.940E-2
1.878E-1
1.000E0
 1 10
50 C0003504 Aortic Valve Insufficiency DisGeNET Curated 4.511E-3 3.002E-2
1.918E-1
1.000E0
 2 244
Show 45 more annotations