Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc61_14, positive side

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1: GO: Molecular Function [Display Chart] 14 input genes in category / 55 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific 4.328E-6 1.326E-4 6.092E-4 2.380E-4 5 357
2 GO:0000982 transcription factor activity, RNA polymerase II proximal promoter sequence-specific DNA binding 4.823E-6 1.326E-4 6.092E-4 2.652E-4 5 365
3 GO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding 1.427E-4 2.368E-3 1.088E-2 7.846E-3 4 379
4 GO:0000987 proximal promoter sequence-specific DNA binding 1.722E-4 2.368E-3 1.088E-2 9.471E-3 4 398
5 GO:0001077 proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific 8.589E-4 9.448E-3 4.340E-2 4.724E-2 3 259
6 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding 1.091E-3 9.999E-3 4.593E-2
5.999E-2
 2 66
7 GO:0004996 thyroid-stimulating hormone receptor activity 1.500E-3 1.179E-2
5.414E-2
8.250E-2
 1 2
8 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding 2.680E-3 1.842E-2
8.463E-2
1.474E-1
 2 104
9 GO:0001046 core promoter sequence-specific DNA binding 3.264E-3 1.873E-2
8.604E-2
1.795E-1
 2 115
10 GO:0005111 type 2 fibroblast growth factor receptor binding 3.746E-3 1.873E-2
8.604E-2
2.060E-1
 1 5
11 GO:0005105 type 1 fibroblast growth factor receptor binding 3.746E-3 1.873E-2
8.604E-2
2.060E-1
 1 5
12 GO:0016015 morphogen activity 5.987E-3 2.513E-2
1.154E-1
3.293E-1
 1 8
13 GO:0001047 core promoter binding 6.518E-3 2.513E-2
1.154E-1
3.585E-1
 2 164
14 GO:0001206 distal enhancer DNA-binding transcription repressor activity, RNA polymerase II-specific 6.733E-3 2.513E-2
1.154E-1
3.703E-1
 1 9
15 GO:0008190 eukaryotic initiation factor 4E binding 7.479E-3 2.513E-2
1.154E-1
4.113E-1
 1 10
16 GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific 7.970E-3 2.513E-2
1.154E-1
4.384E-1
 2 182
17 GO:0016175 superoxide-generating NADPH oxidase activity 8.224E-3 2.513E-2
1.154E-1
4.523E-1
 1 11
18 GO:0070411 I-SMAD binding 8.224E-3 2.513E-2
1.154E-1
4.523E-1
 1 11
19 GO:0070016 armadillo repeat domain binding 9.712E-3 2.811E-2
1.291E-1
5.342E-1
 1 13
20 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific DNA binding 1.046E-2 2.875E-2
1.321E-1
5.751E-1
 1 14
21 GO:0016500 protein-hormone receptor activity 1.194E-2 2.907E-2
1.335E-1
6.568E-1
 1 16
22 GO:0070742 C2H2 zinc finger domain binding 1.194E-2 2.907E-2
1.335E-1
6.568E-1
 1 16
23 GO:0048018 receptor ligand activity 1.268E-2 2.907E-2
1.335E-1
6.976E-1
 1 17
24 GO:0050664 oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor 1.268E-2 2.907E-2
1.335E-1
6.976E-1
 1 17
25 GO:0071837 HMG box domain binding 1.712E-2 3.767E-2
1.731E-1
9.418E-1
 1 23
26 GO:0005104 fibroblast growth factor receptor binding 2.081E-2 4.389E-2
2.016E-1
1.000E0
 1 28
27 GO:0042056 chemoattractant activity 2.155E-2 4.389E-2
2.016E-1
1.000E0
 1 29
28 GO:0030546 receptor activator activity 2.595E-2 4.921E-2
2.261E-1
1.000E0
 1 35
29 GO:0031369 translation initiation factor binding 2.595E-2 4.921E-2
2.261E-1
1.000E0
 1 35
Show 24 more annotations

2: GO: Biological Process [Display Chart] 14 input genes in category / 856 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0003002 regionalization 5.671E-17 4.854E-14 3.558E-13 4.854E-14 11 370
2 GO:0007389 pattern specification process 1.421E-15 6.080E-13 4.457E-12 1.216E-12 11 495
3 GO:0009952 anterior/posterior pattern specification 1.091E-12 3.113E-10 2.282E-9 9.340E-10 8 224
4 GO:0042471 ear morphogenesis 2.521E-12 5.395E-10 3.954E-9 2.158E-9 7 132
5 GO:0048562 embryonic organ morphogenesis 2.219E-11 3.798E-9 2.784E-8 1.899E-8 8 326
6 GO:0010092 specification of animal organ identity 3.995E-11 5.700E-9 4.178E-8 3.420E-8 5 36
7 GO:0071542 dopaminergic neuron differentiation 6.094E-11 7.452E-9 5.463E-8 5.217E-8 5 39
8 GO:0042472 inner ear morphogenesis 1.011E-10 1.082E-8 7.931E-8 8.656E-8 6 109
9 GO:0043583 ear development 1.670E-10 1.588E-8 1.164E-7 1.429E-7 7 239
10 GO:0060485 mesenchyme development 3.351E-10 2.868E-8 2.102E-7 2.868E-7 7 264
11 GO:0048568 embryonic organ development 4.740E-10 3.688E-8 2.703E-7 4.057E-7 8 479
12 GO:0090596 sensory organ morphogenesis 7.450E-10 5.314E-8 3.895E-7 6.377E-7 7 296
13 GO:0048863 stem cell differentiation 8.768E-10 5.773E-8 4.232E-7 7.505E-7 7 303
14 GO:0048645 animal organ formation 1.175E-9 7.186E-8 5.267E-7 1.006E-6 5 69
15 GO:0021915 neural tube development 2.411E-9 1.376E-7 1.008E-6 2.064E-6 6 184
16 GO:0048762 mesenchymal cell differentiation 3.979E-9 2.129E-7 1.560E-6 3.406E-6 6 200
17 GO:0048839 inner ear development 5.332E-9 2.685E-7 1.968E-6 4.564E-6 6 210
18 GO:0061053 somite development 5.682E-9 2.702E-7 1.981E-6 4.864E-6 5 94
19 GO:2000027 regulation of animal organ morphogenesis 2.290E-8 1.032E-6 7.562E-6 1.960E-5 6 268
20 GO:0045165 cell fate commitment 2.613E-8 1.118E-6 8.196E-6 2.236E-5 6 274
21 GO:0030917 midbrain-hindbrain boundary development 2.833E-8 1.155E-6 8.466E-6 2.425E-5 3 9
22 GO:0021532 neural tube patterning 3.202E-8 1.246E-6 9.132E-6 2.741E-5 4 46
23 GO:0021903 rostrocaudal neural tube patterning 9.630E-8 3.584E-6 2.627E-5 8.243E-5 3 13
24 GO:2001053 regulation of mesenchymal cell apoptotic process 1.225E-7 4.236E-6 3.105E-5 1.049E-4 3 14
25 GO:0001658 branching involved in ureteric bud morphogenesis 1.237E-7 4.236E-6 3.105E-5 1.059E-4 4 64
26 GO:0021527 spinal cord association neuron differentiation 1.531E-7 4.853E-6 3.557E-5 1.310E-4 3 15
27 GO:0097152 mesenchymal cell apoptotic process 1.531E-7 4.853E-6 3.557E-5 1.310E-4 3 15
28 GO:0060562 epithelial tube morphogenesis 1.626E-7 4.902E-6 3.593E-5 1.392E-4 6 373
29 GO:0048754 branching morphogenesis of an epithelial tube 1.661E-7 4.902E-6 3.593E-5 1.422E-4 5 184
30 GO:0014031 mesenchymal cell development 1.753E-7 4.917E-6 3.604E-5 1.500E-4 5 186
31 GO:0060675 ureteric bud morphogenesis 1.781E-7 4.917E-6 3.604E-5 1.524E-4 4 70
32 GO:0072171 mesonephric tubule morphogenesis 1.886E-7 5.045E-6 3.698E-5 1.615E-4 4 71
33 GO:0048864 stem cell development 2.053E-7 5.303E-6 3.887E-5 1.757E-4 5 192
34 GO:0060348 bone development 2.106E-7 5.303E-6 3.887E-5 1.803E-4 5 193
35 GO:0001756 somitogenesis 2.485E-7 5.979E-6 4.383E-5 2.127E-4 4 76
36 GO:0021953 central nervous system neuron differentiation 2.515E-7 5.979E-6 4.383E-5 2.153E-4 5 200
37 GO:0030900 forebrain development 2.719E-7 6.219E-6 4.558E-5 2.328E-4 6 407
38 GO:0048663 neuron fate commitment 2.761E-7 6.219E-6 4.558E-5 2.363E-4 4 78
39 GO:0072078 nephron tubule morphogenesis 2.907E-7 6.380E-6 4.676E-5 2.488E-4 4 79
40 GO:0035239 tube morphogenesis 3.049E-7 6.525E-6 4.783E-5 2.610E-4 6 415
41 GO:0072088 nephron epithelium morphogenesis 3.216E-7 6.714E-6 4.921E-5 2.753E-4 4 81
42 GO:0072028 nephron morphogenesis 3.549E-7 7.065E-6 5.178E-5 3.038E-4 4 83
43 GO:0021536 diencephalon development 3.549E-7 7.065E-6 5.178E-5 3.038E-4 4 83
44 GO:0061333 renal tubule morphogenesis 3.725E-7 7.246E-6 5.311E-5 3.188E-4 4 84
45 GO:0061138 morphogenesis of a branching epithelium 4.128E-7 7.487E-6 5.488E-5 3.533E-4 5 221
46 GO:0021516 dorsal spinal cord development 5.165E-7 7.487E-6 5.488E-5 4.421E-4 3 22
47 GO:0072304 regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis 5.248E-7 7.487E-6 5.488E-5 4.492E-4 2 2
48 GO:0039017 pattern specification involved in pronephros development 5.248E-7 7.487E-6 5.488E-5 4.492E-4 2 2
49 GO:0039003 pronephric field specification 5.248E-7 7.487E-6 5.488E-5 4.492E-4 2 2
50 GO:0072305 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis 5.248E-7 7.487E-6 5.488E-5 4.492E-4 2 2
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 14 input genes in category / 22 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0005667 transcription factor complex 6.218E-13 1.368E-11 5.049E-11 1.368E-11 9 368

4: Human Phenotype [Display Chart] 12 input genes in category / 864 annotations before applied cutoff / 4707 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 HP:0009117 Aplasia/Hypoplasia of the maxilla 4.709E-6 3.071E-3 2.254E-2 4.068E-3 6 205
2 HP:0000326 Abnormality of the maxilla 7.108E-6 3.071E-3 2.254E-2 6.141E-3 6 220
3 HP:0001592 Selective tooth agenesis 4.003E-5 1.153E-2
8.461E-2
 3.458E-2 3 28
4 HP:0000677 Oligodontia 1.187E-4 2.322E-2
1.704E-1
1.025E-1
 3 40
5 HP:0000327 Hypoplasia of the maxilla 1.344E-4 2.322E-2
1.704E-1
1.161E-1
 4 113
6 HP:0002692 Hypoplastic facial bones 2.183E-4 3.144E-2
2.307E-1
1.886E-1
 6 401
Show 1 more annotation

5: Mouse Phenotype [Display Chart] 14 input genes in category / 1495 annotations before applied cutoff / 10355 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 MP:0000049 abnormal middle ear morphology 5.517E-13 8.249E-10 6.506E-9 8.249E-10 8 116
2 MP:0000899 abnormal corpora quadrigemina morphology 1.564E-12 1.169E-9 9.223E-9 2.339E-9 6 32
3 MP:0006103 abnormal midbrain roof plate morphology 7.716E-12 2.884E-9 2.275E-8 1.154E-8 6 41
4 MP:0006104 abnormal tectum morphology 7.716E-12 2.884E-9 2.275E-8 1.154E-8 6 41
5 MP:0000776 abnormal inferior colliculus morphology 3.098E-11 9.262E-9 7.305E-8 4.631E-8 5 20
6 MP:0005272 abnormal temporal bone morphology 5.025E-10 1.128E-7 8.900E-7 7.512E-7 6 80
7 MP:0005105 abnormal middle ear ossicle morphology 5.847E-10 1.128E-7 8.900E-7 8.742E-7 6 82
8 MP:0000897 abnormal midbrain morphology 6.038E-10 1.128E-7 8.900E-7 9.027E-7 7 161
9 MP:0012133 absent midbrain-hindbrain boundary 6.862E-10 1.140E-7 8.991E-7 1.026E-6 4 11
10 MP:0000074 abnormal neurocranium morphology 1.022E-9 1.528E-7 1.205E-6 1.528E-6 8 295
11 MP:0002102 abnormal ear morphology 1.892E-9 2.572E-7 2.029E-6 2.829E-6 9 493
12 MP:0000850 absent cerebellum 4.926E-9 6.137E-7 4.841E-6 7.365E-6 4 17
13 MP:0010029 abnormal basicranium morphology 1.107E-8 1.247E-6 9.839E-6 1.654E-5 6 133
14 MP:0005277 abnormal brainstem morphology 1.168E-8 1.247E-6 9.839E-6 1.746E-5 7 246
15 MP:0012132 abnormal midbrain-hindbrain boundary morphology 1.824E-8 1.818E-6 1.434E-5 2.727E-5 4 23
16 MP:0000737 abnormal myotome development 2.187E-8 2.044E-6 1.612E-5 3.270E-5 4 24
17 MP:0004592 small mandible 2.999E-8 2.637E-6 2.080E-5 4.484E-5 6 157
18 MP:0000455 abnormal maxilla morphology 3.487E-8 2.896E-6 2.284E-5 5.213E-5 6 161
19 MP:0000933 abnormal rhombomere morphology 4.202E-8 3.306E-6 2.608E-5 6.282E-5 4 28
20 MP:0000026 abnormal inner ear morphology 4.714E-8 3.467E-6 2.735E-5 7.047E-5 7 301
21 MP:0003208 abnormal neuromere morphology 4.871E-8 3.467E-6 2.735E-5 7.281E-5 4 29
22 MP:0030385 absent facial bone 6.251E-8 4.091E-6 3.227E-5 9.345E-5 5 85
23 MP:0000454 abnormal jaw morphology 6.293E-8 4.091E-6 3.227E-5 9.409E-5 8 498
24 MP:0004452 abnormal pterygoid process morphology 9.473E-8 5.901E-6 4.655E-5 1.416E-4 4 34
25 MP:0003235 abnormal alisphenoid bone morphology 1.069E-7 6.310E-6 4.977E-5 1.598E-4 4 35
26 MP:0003931 absent molars 1.097E-7 6.310E-6 4.977E-5 1.641E-4 3 8
27 MP:0006011 abnormal endolymphatic duct morphology 1.201E-7 6.652E-6 5.247E-5 1.796E-4 4 36
28 MP:0009038 decreased inferior colliculus size 1.645E-7 8.782E-6 6.927E-5 2.459E-4 3 9
29 MP:0000104 abnormal sphenoid bone morphology 1.902E-7 9.805E-6 7.734E-5 2.843E-4 5 106
30 MP:0012168 abnormal optic placode morphology 2.348E-7 1.170E-5 9.229E-5 3.510E-4 3 10
31 MP:0000458 abnormal mandible morphology 2.911E-7 1.367E-5 1.078E-4 4.353E-4 6 230
32 MP:0003720 abnormal neural tube closure 2.982E-7 1.367E-5 1.078E-4 4.459E-4 7 394
33 MP:0003864 abnormal midbrain development 3.018E-7 1.367E-5 1.078E-4 4.512E-4 4 45
34 MP:0000864 abnormal cerebellum vermis morphology 3.607E-7 1.586E-5 1.251E-4 5.393E-4 4 47
35 MP:0002200 abnormal brain ventricular system morphology 3.846E-7 1.624E-5 1.281E-4 5.750E-4 7 409
36 MP:0000163 abnormal cartilage morphology 3.911E-7 1.624E-5 1.281E-4 5.847E-4 7 410
37 MP:0004096 abnormal midbrain-hindbrain boundary development 4.298E-7 1.736E-5 1.370E-4 6.425E-4 3 12
38 MP:0002820 abnormal premaxilla morphology 5.038E-7 1.982E-5 1.563E-4 7.532E-4 4 51
39 MP:0003935 abnormal craniofacial development 5.666E-7 2.172E-5 1.713E-4 8.471E-4 7 433
40 MP:0000929 open neural tube 6.137E-7 2.294E-5 1.809E-4 9.174E-4 6 261
41 MP:0000035 abnormal membranous labyrinth morphology 6.711E-7 2.447E-5 1.930E-4 1.003E-3 6 265
42 MP:0000090 absent premaxilla 7.099E-7 2.527E-5 1.993E-4 1.061E-3 3 14
43 MP:0000914 exencephaly 8.521E-7 2.882E-5 2.273E-4 1.274E-3 6 276
44 MP:0000562 polydactyly 8.780E-7 2.882E-5 2.273E-4 1.313E-3 5 144
45 MP:0004206 abnormal dermomyotome development 8.867E-7 2.882E-5 2.273E-4 1.326E-3 3 15
46 MP:0003421 abnormal thyroid gland development 8.867E-7 2.882E-5 2.273E-4 1.326E-3 3 15
47 MP:0009846 abnormal neural crest morphology 9.119E-7 2.901E-5 2.288E-4 1.363E-3 4 59
48 MP:0030878 abnormal fibrous joint morphology 9.727E-7 3.029E-5 2.389E-4 1.454E-3 5 147
49 MP:0006400 decreased molar number 1.090E-6 3.261E-5 2.572E-4 1.630E-3 3 16
50 MP:0004912 absent mandibular coronoid process 1.090E-6 3.261E-5 2.572E-4 1.630E-3 3 16
Show 45 more annotations

6: Domain [Display Chart] 14 input genes in category / 61 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS51057 PAIRED 2 PROSITE 7.188E-26 8.769E-25 4.118E-24 4.385E-24 8 9
2 IPR001523 Paired dom InterPro 7.188E-26 8.769E-25 4.118E-24 4.385E-24 8 9
3 PF00292 PAX Pfam 7.188E-26 8.769E-25 4.118E-24 4.385E-24 8 9
4 SM00351 PAX SMART 7.188E-26 8.769E-25 4.118E-24 4.385E-24 8 9
5 PS00034 PAIRED 1 PROSITE 7.188E-26 8.769E-25 4.118E-24 4.385E-24 8 9
6 IPR009057 Homeodomain-like InterPro 1.593E-17 1.620E-16 7.608E-16 9.720E-16 11 332
7 1.10.10.10 - Gene3D 8.358E-13 7.283E-12 3.420E-11 5.098E-11 8 218
8 IPR011991 WHTH DNA-bd dom InterPro 2.005E-12 1.529E-11 7.178E-11 1.223E-10 8 243
9 IPR022130 Pax2 C InterPro 3.322E-10 2.026E-9 9.516E-9 2.026E-8 3 3
10 PF12403 Pax2 C Pfam 3.322E-10 2.026E-9 9.516E-9 2.026E-8 3 3
11 1.10.10.60 - Gene3D 5.225E-10 2.897E-9 1.361E-8 3.187E-8 7 283
12 IPR017970 Homeobox CS InterPro 2.483E-9 1.262E-8 5.927E-8 1.515E-7 6 186
13 PF00046 Homeobox Pfam 9.835E-9 4.005E-8 1.881E-7 6.000E-7 6 234
14 PS00027 HOMEOBOX 1 PROSITE 1.035E-8 4.005E-8 1.881E-7 6.313E-7 6 236
15 SM00389 HOX SMART 1.061E-8 4.005E-8 1.881E-7 6.474E-7 6 237
16 PS50071 HOMEOBOX 2 PROSITE 1.116E-8 4.005E-8 1.881E-7 6.808E-7 6 239
17 IPR001356 Homeobox dom InterPro 1.116E-8 4.005E-8 1.881E-7 6.808E-7 6 239
18 IPR022106 Pax7 C InterPro 5.185E-7 1.665E-6 7.818E-6 3.163E-5 2 2
19 PF12360 Pax7 Pfam 5.185E-7 1.665E-6 7.818E-6 3.163E-5 2 2
20 IPR033038 Pax3 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
21 IPR033206 PAX1 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
22 IPR009139 Wnt1 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
23 IPR003022 Otx2 TF InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
24 IPR028249 FGF8 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
25 IPR031250 GBX-2 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
26 IPR033559 Pax-4 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
27 IPR033204 PAX9 InterPro 7.473E-4 1.688E-3 7.929E-3 4.558E-2 1 1
28 IPR014936 Axin b-cat-bd InterPro 1.494E-3 2.848E-3 1.337E-2
9.113E-2
 1 2
29 IPR003025 Otx TF InterPro 1.494E-3 2.848E-3 1.337E-2
9.113E-2
 1 2
30 PF16646 AXIN1 TNKS BD Pfam 1.494E-3 2.848E-3 1.337E-2
9.113E-2
 1 2
31 IPR032101 Axin TNKS-bd InterPro 1.494E-3 2.848E-3 1.337E-2
9.113E-2
 1 2
32 PF08833 Axin b-cat bind Pfam 1.494E-3 2.848E-3 1.337E-2
9.113E-2
 1 2
33 IPR020479 Homeobox metazoa InterPro 2.000E-3 3.697E-3 1.736E-2
1.220E-1
 2 90
34 IPR013851 Otx TF C InterPro 2.240E-3 3.904E-3 1.834E-2
1.367E-1
 1 3
35 PF03529 TF Otx Pfam 2.240E-3 3.904E-3 1.834E-2
1.367E-1
 1 3
36 SM00021 DAX SMART 5.220E-3 8.165E-3 3.834E-2
3.184E-1
 1 7
37 PS50841 DIX PROSITE 5.220E-3 8.165E-3 3.834E-2
3.184E-1
 1 7
38 IPR001158 DIX InterPro 5.220E-3 8.165E-3 3.834E-2
3.184E-1
 1 7
39 PF00778 DIX Pfam 5.220E-3 8.165E-3 3.834E-2
3.184E-1
 1 7
40 IPR001564 Nucleoside diP kinase InterPro 8.933E-3 1.362E-2
6.398E-2
5.449E-1
 1 12
41 PS50803 OAR PROSITE 1.189E-2 1.727E-2
8.113E-2
7.255E-1
 1 16
42 IPR003654 OAR dom InterPro 1.189E-2 1.727E-2
8.113E-2
7.255E-1
 1 16
43 IPR018161 Wnt CS InterPro 1.411E-2 1.831E-2
8.600E-2
8.607E-1
 1 19
44 PF00110 wnt Pfam 1.411E-2 1.831E-2
8.600E-2
8.607E-1
 1 19
45 IPR005817 Wnt InterPro 1.411E-2 1.831E-2
8.600E-2
8.607E-1
 1 19
46 SM00097 WNT1 SMART 1.411E-2 1.831E-2
8.600E-2
8.607E-1
 1 19
47 PS00246 WNT1 PROSITE 1.411E-2 1.831E-2
8.600E-2
8.607E-1
 1 19
48 IPR024066 RGS subdom1 InterPro 1.632E-2 1.878E-2
8.821E-2
9.956E-1
 1 22
49 PF00167 FGF Pfam 1.632E-2 1.878E-2
8.821E-2
9.956E-1
 1 22
50 IPR002209 Fibroblast GF fam InterPro 1.632E-2 1.878E-2
8.821E-2
9.956E-1
 1 22
Show 45 more annotations

7: Pathway [Display Chart] 9 input genes in category / 164 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 523016 Transcriptional misregulation in cancer BioSystems: KEGG 5.032E-6 8.252E-4 4.687E-3 8.252E-4 4 180
2 83105 Pathways in cancer BioSystems: KEGG 1.108E-4 6.613E-3 3.756E-2 1.817E-2 4 395
3 1435207 Breast cancer BioSystems: KEGG 1.210E-4 6.613E-3 3.756E-2 1.984E-2 3 144
4 PW:0000201 canonical Wnt signaling Pathway Ontology 4.729E-4 1.939E-2
1.101E-1
7.756E-2
 2 46
5 83113 Basal cell carcinoma BioSystems: KEGG 6.763E-4 2.218E-2
1.260E-1
1.109E-1
 2 55
6 138073 C-MYB transcription factor network BioSystems: Pathway Interaction Database 1.356E-3 3.706E-2
2.105E-1
2.224E-1
 2 78
Show 1 more annotation

8: Pubmed [Display Chart] 14 input genes in category / 6051 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 7981748 Chromosomal localization of seven PAX genes and cloning of a novel family member, PAX-9. Pubmed 2.408E-28 4.857E-25 4.510E-24 1.457E-24 8 9
2 7883790 Pax genes in development. Pubmed 2.408E-28 4.857E-25 4.510E-24 1.457E-24 8 9
3 10197584 Pax genes and their role in organogenesis. Pubmed 2.408E-28 4.857E-25 4.510E-24 1.457E-24 8 9
4 11704761 Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8. Pubmed 1.168E-24 1.767E-21 1.640E-20 7.066E-21 7 8
5 18480159 Gli3 coordinates three-dimensional patterning and growth of the tectum and cerebellum by integrating Shh and Fgf8 signaling. Pubmed 4.171E-23 4.856E-20 4.509E-19 2.524E-19 8 26
6 10354469 Pax2/5 and Pax6 subdivide the early neural tube into three domains. Pubmed 4.815E-23 4.856E-20 4.509E-19 2.913E-19 7 11
7 1685142 Pax: a murine multigene family of paired box-containing genes. Pubmed 1.668E-21 1.442E-18 1.339E-17 1.009E-17 7 16
8 11500373 Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain. Pubmed 7.342E-21 5.553E-18 5.156E-17 4.443E-17 7 19
9 16530751 Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Pubmed 3.217E-19 2.163E-16 2.008E-15 1.946E-15 6 11
10 20532162 beta-Catenin regulates intercellular signalling networks and cell-type specific transcription in the developing mouse midbrain-rhombomere 1 region. Pubmed 1.291E-17 7.811E-15 7.253E-14 7.811E-14 6 18
11 8431641 Mapping of the human homologs of the murine paired-box-containing genes. Pubmed 1.774E-17 8.153E-15 7.570E-14 1.073E-13 5 6
12 1485966 Molecular genetics of the Pax gene family. Pubmed 1.774E-17 8.153E-15 7.570E-14 1.073E-13 5 6
13 8126546 Roles of Pax-genes in developing and adult brain as suggested by expression patterns. Pubmed 1.774E-17 8.153E-15 7.570E-14 1.073E-13 5 6
14 8575294 A role for En-2 and other murine homologues of Drosophila segment polarity genes in regulating positional information in the developing cerebellum. Pubmed 1.886E-17 8.153E-15 7.570E-14 1.141E-13 6 19
15 20206242 A refined map of early gene expression in the dorsal rhombomere 1 of mouse embryos. Pubmed 3.771E-17 1.521E-14 1.413E-13 2.282E-13 6 21
16 9405645 Conserved biological function between Pax-2 and Pax-5 in midbrain and cerebellum development: evidence from targeted mutations. Pubmed 6.207E-17 2.347E-14 2.180E-13 3.756E-13 5 7
17 24335253 Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Pubmed 9.349E-17 2.978E-14 2.765E-13 5.657E-13 6 24
18 16571633 Sp8 controls the anteroposterior patterning at the midbrain-hindbrain border. Pubmed 9.349E-17 2.978E-14 2.765E-13 5.657E-13 6 24
19 11493561 Emx2 directs the development of diencephalon in cooperation with Otx2. Pubmed 9.349E-17 2.978E-14 2.765E-13 5.657E-13 6 24
20 11124114 EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Pubmed 1.655E-16 5.007E-14 4.649E-13 1.001E-12 5 8
21 11731459 Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Pubmed 7.444E-16 2.047E-13 1.901E-12 4.504E-12 5 10
22 10518499 FGF8 can activate Gbx2 and transform regions of the rostral mouse brain into a hindbrain fate. Pubmed 7.444E-16 2.047E-13 1.901E-12 4.504E-12 5 10
23 12736208 The isthmic organizer signal FGF8 is required for cell survival in the prospective midbrain and cerebellum. Pubmed 1.364E-15 3.176E-13 2.949E-12 8.257E-12 5 11
24 15580630 Phenotypic analyses of mouse embryos with ubiquitous expression of Oct4: effects on mid-hindbrain patterning and gene expression. Pubmed 1.364E-15 3.176E-13 2.949E-12 8.257E-12 5 11
25 21246658 Autotaxin is required for the cranial neural tube closure and establishment of the midbrain-hindbrain boundary during mouse development. Pubmed 1.364E-15 3.176E-13 2.949E-12 8.257E-12 5 11
26 20652258 Mitochondrial retention of Opa1 is required for mouse embryogenesis. Pubmed 1.364E-15 3.176E-13 2.949E-12 8.257E-12 5 11
27 25800090 Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects. Pubmed 2.339E-15 4.880E-13 4.531E-12 1.415E-11 5 12
28 11748135 Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Pubmed 2.339E-15 4.880E-13 4.531E-12 1.415E-11 5 12
29 9486536 Cooperation between Otx1 and Otx2 genes in developmental patterning of rostral brain. Pubmed 2.339E-15 4.880E-13 4.531E-12 1.415E-11 5 12
30 9342056 Genetic control of brain morphogenesis through Otx gene dosage requirement. Pubmed 3.800E-15 6.967E-13 6.469E-12 2.299E-11 5 13
31 21698205 The lineage contribution and role of Gbx2 in spinal cord development. Pubmed 3.800E-15 6.967E-13 6.469E-12 2.299E-11 5 13
32 15121182 Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region. Pubmed 3.800E-15 6.967E-13 6.469E-12 2.299E-11 5 13
33 17360769 Lack of the murine homeobox gene Hesx1 leads to a posterior transformation of the anterior forebrain. Pubmed 3.800E-15 6.967E-13 6.469E-12 2.299E-11 5 13
34 14651936 Anterior neural plate regionalization in cripto null mutant mouse embryos in the absence of node and primitive streak. Pubmed 5.909E-15 1.052E-12 9.765E-12 3.576E-11 5 14
35 15207855 Forced expression of platelet-derived growth factor B in the mouse cerebellar primordium changes cell migration during midline fusion and causes cerebellar ectopia. Pubmed 8.862E-15 1.449E-12 1.346E-11 5.363E-11 5 15
36 18930042 Intraflagellar transport protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain. Pubmed 8.862E-15 1.449E-12 1.346E-11 5.363E-11 5 15
37 8837770 Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Pubmed 8.862E-15 1.449E-12 1.346E-11 5.363E-11 5 15
38 18929642 Identification and characterization of VPO1, a new animal heme-containing peroxidase. Pubmed 1.289E-14 1.950E-12 1.810E-11 7.799E-11 5 16
39 16423343 The mouse Ovol2 gene is required for cranial neural tube development. Pubmed 1.289E-14 1.950E-12 1.810E-11 7.799E-11 5 16
40 18216176 Specific regions within the embryonic midbrain and cerebellum require different levels of FGF signaling during development. Pubmed 1.289E-14 1.950E-12 1.810E-11 7.799E-11 5 16
41 17166916 Lmx1b is essential for Fgf8 and Wnt1 expression in the isthmic organizer during tectum and cerebellum development in mice. Pubmed 2.527E-14 3.556E-12 3.302E-11 1.529E-10 5 18
42 21930923 Involvement of retinol dehydrogenase 10 in embryonic patterning and rescue of its loss of function by maternal retinaldehyde treatment. Pubmed 2.527E-14 3.556E-12 3.302E-11 1.529E-10 5 18
43 12682014 FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. Pubmed 2.527E-14 3.556E-12 3.302E-11 1.529E-10 5 18
44 18429041 Ventral specification and perturbed boundary formation in the mouse midbrain in the absence of Hedgehog signaling. Pubmed 3.429E-14 4.715E-12 4.378E-11 2.075E-10 5 19
45 27302397 Tcf7l1 protects the anterior neural fold from adopting the neural crest fate. Pubmed 4.571E-14 6.013E-12 5.583E-11 2.766E-10 5 20
46 15105374 FKBP8 is a negative regulator of mouse sonic hedgehog signaling in neural tissues. Pubmed 4.571E-14 6.013E-12 5.583E-11 2.766E-10 5 20
47 10490024 A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. Pubmed 5.645E-14 7.116E-12 6.608E-11 3.416E-10 4 5
48 8099544 The oncogenic potential of Pax genes. Pubmed 5.645E-14 7.116E-12 6.608E-11 3.416E-10 4 5
49 17241623 Defects in brain patterning and head morphogenesis in the mouse mutant Fused toes. Pubmed 7.761E-14 9.584E-12 8.899E-11 4.696E-10 5 22
50 22993445 A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation. Pubmed 1.252E-13 1.486E-11 1.379E-10 7.577E-10 5 24
Show 45 more annotations

9: Interaction [Display Chart] 13 input genes in category / 322 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:TLE4 TLE4 interactions 1.417E-8 4.563E-6 2.899E-5 4.563E-6 4 39
2 int:MSX1 MSX1 interactions 1.374E-6 2.212E-4 1.406E-3 4.425E-4 3 31
3 int:LEF1 LEF1 interactions 7.095E-6 7.615E-4 4.838E-3 2.285E-3 3 53
4 int:ID2 ID2 interactions 3.274E-5 2.636E-3 1.675E-2 1.054E-2 3 88
5 int:PAX9 PAX9 interactions 5.199E-5 3.348E-3 2.127E-2 1.674E-2 2 15
6 int:SFRP2 SFRP2 interactions 1.037E-4 5.566E-3 3.536E-2 3.340E-2 2 21
7 int:TLE2 TLE2 interactions 1.361E-4 6.263E-3 3.979E-2 4.384E-2 2 24
8 int:DAXX DAXX interactions 2.359E-4 9.494E-3
6.032E-2
7.595E-2
 3 171
9 int:TBP TBP interactions 3.020E-4 9.957E-3
6.326E-2
9.726E-2
 3 186
10 int:PAX3 PAX3 interactions 3.092E-4 9.957E-3
6.326E-2
9.957E-2
 2 36
11 int:MEOX1 MEOX1 interactions 3.633E-4 1.063E-2
6.756E-2
1.170E-1
 2 39
12 int:ALX4 ALX4 interactions 4.628E-4 1.199E-2
7.618E-2
1.490E-1
 2 44
13 int:MITF MITF interactions 4.841E-4 1.199E-2
7.618E-2
1.559E-1
 2 45
14 int:RB1 RB1 interactions 8.674E-4 1.995E-2
1.268E-1
2.793E-1
 3 267
15 int:KDM5B KDM5B interactions 1.071E-3 2.300E-2
1.461E-1
3.450E-1
 2 67
16 int:DMBX1 DMBX1 interactions 1.468E-3 2.955E-2
1.877E-1
4.728E-1
 1 2
17 int:HIRA HIRA interactions 1.638E-3 3.072E-2
1.952E-1
5.275E-1
 2 83
18 int:TAF1 TAF1 interactions 1.717E-3 3.072E-2
1.952E-1
5.529E-1
 2 85
19 int:PAX1 PAX1 interactions 2.202E-3 3.588E-2
2.279E-1
7.089E-1
 1 3
20 int:MYOD1 MYOD1 interactions 2.228E-3 3.588E-2
2.279E-1
7.175E-1
 2 97
21 int:TLE1 TLE1 interactions 3.221E-3 4.373E-2
2.778E-1
1.000E0
 2 117
22 int:PAX4 PAX4 interactions 3.667E-3 4.373E-2
2.778E-1
1.000E0
 1 5
23 int:ANKRD6 ANKRD6 interactions 3.667E-3 4.373E-2
2.778E-1
1.000E0
 1 5
24 int:MC5R MC5R interactions 3.667E-3 4.373E-2
2.778E-1
1.000E0
 1 5
25 int:SSX4 SSX4 interactions 3.667E-3 4.373E-2
2.778E-1
1.000E0
 1 5
26 int:MC3R MC3R interactions 3.667E-3 4.373E-2
2.778E-1
1.000E0
 1 5
27 int:PCTP PCTP interactions 3.667E-3 4.373E-2
2.778E-1
1.000E0
 1 5
Show 22 more annotations

10: Cytoband [Display Chart] 14 input genes in category / 13 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 10q24 10q24 8.946E-5 1.163E-3 3.698E-3 1.163E-3 2 35
2 17q23-q24 17q23-q24 1.211E-3 6.997E-3 2.225E-2 1.575E-2 1 3
3 2q37.2 2q37.2 1.615E-3 6.997E-3 2.225E-2 2.099E-2 1 4
4 4p16.2 4p16.2 2.421E-3 7.869E-3 2.502E-2 3.148E-2 1 6
5 20p11.2 20p11.2 4.435E-3 1.048E-2 3.333E-2
5.765E-2
 1 11
6 14q13.3 14q13.3 4.837E-3 1.048E-2 3.333E-2
6.288E-2
 1 12
7 9p13 9p13 9.252E-3 1.568E-2 4.985E-2
1.203E-1
 1 23
8 7q32 7q32 9.652E-3 1.568E-2 4.985E-2
1.255E-1
 1 24
9 14q22.3 14q22.3 1.085E-2 1.568E-2 4.985E-2
1.411E-1
 1 27
10 1p36.13 1p36.13 2.712E-2 3.066E-2
9.751E-2
3.526E-1
 1 68
11 12q13 12q13 2.830E-2 3.066E-2
9.751E-2
3.680E-1
 1 71
12 2q13 2q13 2.830E-2 3.066E-2
9.751E-2
3.680E-1
 1 71
13 2q35 2q35 3.223E-2 3.223E-2
1.025E-1
4.190E-1
 1 81
Show 8 more annotations

11: Transcription Factor Binding Site [Display Chart] 13 input genes in category / 268 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$HNF6 Q6 V$HNF6 Q6 3.666E-6 9.824E-4 6.061E-3 9.824E-4 5 198
2 V$PAX4 02 V$PAX4 02 1.054E-4 1.413E-2
8.715E-2
 2.825E-2 4 200
3 V$PBX1 02 V$PBX1 02 3.561E-4 3.182E-2
1.963E-1
9.545E-2
 3 109
4 V$NCX 01 V$NCX 01 7.726E-4 4.208E-2
2.597E-1
2.071E-1
 3 142
5 V$TFIII Q6 V$TFIII Q6 1.347E-3 4.208E-2
2.597E-1
3.609E-1
 3 172
6 WTTGKCTG UNKNOWN WTTGKCTG UNKNOWN 1.690E-3 4.208E-2
2.597E-1
4.528E-1
 4 415
7 V$SMAD3 Q6 V$SMAD3 Q6 1.876E-3 4.208E-2
2.597E-1
5.027E-1
 3 193
8 V$CHX10 01 V$CHX10 01 1.932E-3 4.208E-2
2.597E-1
5.177E-1
 3 195
9 V$PIT1 Q6 V$PIT1 Q6 1.960E-3 4.208E-2
2.597E-1
5.254E-1
 3 196
10 V$SMAD4 Q6 V$SMAD4 Q6 2.077E-3 4.208E-2
2.597E-1
5.567E-1
 3 200
11 V$SREBP Q3 V$SREBP Q3 2.107E-3 4.208E-2
2.597E-1
5.647E-1
 3 201
12 V$LMO2COM 01 V$LMO2COM 01 2.137E-3 4.208E-2
2.597E-1
5.727E-1
 3 202
13 V$DBP Q6 V$DBP Q6 2.198E-3 4.208E-2
2.597E-1
5.891E-1
 3 204
14 V$AP2 Q3 V$AP2 Q3 2.292E-3 4.208E-2
2.597E-1
6.142E-1
 3 207
15 V$GR Q6 01 V$GR Q6 01 2.355E-3 4.208E-2
2.597E-1
6.312E-1
 3 209
16 GGATTA V$PITX2 Q2 GGATTA V$PITX2 Q2 2.973E-3 4.697E-2
2.898E-1
7.969E-1
 4 484
17 YKACATTT UNKNOWN YKACATTT UNKNOWN 2.980E-3 4.697E-2
2.898E-1
7.985E-1
 3 227
Show 12 more annotations

12: Gene Family [Display Chart] 13 input genes in category / 6 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 675 PRD class homeoboxes and pseudogenes|Paired boxes genenames.org 3.895E-26 2.337E-25 5.725E-25 2.337E-25 8 9
2 521 PRD class homeoboxes and pseudogenes genenames.org 1.122E-13 3.365E-13 8.243E-13 6.729E-13 7 92
3 542 Endogenous ligands genenames.org 1.199E-2 2.024E-2 4.960E-2
7.194E-2
 2 237
4 360 Wnt family genenames.org 1.350E-2 2.024E-2 4.960E-2
8.097E-2
 1 19
5 518 HOXL subclass homeoboxes genenames.org 3.654E-2 4.384E-2
1.074E-1
2.192E-1
 1 52
6 519 NKL subclass homeoboxes and pseudogenes genenames.org 4.684E-2 4.684E-2
1.148E-1
2.811E-1
 1 67
Show 1 more annotation

13: Coexpression [Display Chart] 14 input genes in category / 824 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M1938 Genes with high-CpG-density promoters (HCP) bearing the H3K27 tri-methylation (H3K27me3) mark in brain. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.761E-7 3.099E-4 2.260E-3 3.099E-4 5 269
2 M1949 Genes with high-CpG-density promoters (HCP) bearing histone H3 dimethylation mark at K4 (H3K4me2) and trimethylation mark at K27 (H3K27me3) in neural precursor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.359E-6 5.597E-4 4.081E-3 1.119E-3 5 349
3 M19304 Genes up-regulated in hES cells (human embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.396E-6 9.329E-4 6.803E-3 2.799E-3 2 5
4 19137020-SuppTable2a Human StemCell Fukuzawa09 114genes GeneSigDB 6.217E-6 1.175E-3 8.565E-3 5.123E-3 3 61
5 M1761 Genes up-regulated in EpiSC cells (mouse epiblast embryonic stem cells) after treatment with the ALK [GeneID=238] inhibitor SB-431542 [PubChem=4521392]. MSigDB C2: CGP Curated Gene Sets (v6.0) 7.128E-6 1.175E-3 8.565E-3 5.873E-3 2 7
6 18787207-Table1 Mouse Viral Craft08 83genes GeneSigDB 1.115E-5 1.531E-3 1.116E-2 9.184E-3 3 74
7 M9150 Genes from common genomic gains observed in a meta analyis of copy number alterations across a panel of different cancer cell lines and tumor samples. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.342E-5 3.933E-3 2.868E-2 2.753E-2 4 323
8 M2009 Genes with high-CpG-density promoters (HCP) bearing histone H3 trimethylation mark at K27 (H3K27me3) in neural progenitor cells (NPC). MSigDB C2: CGP Curated Gene Sets (v6.0) 4.129E-5 4.212E-3 3.071E-2 3.402E-2 4 341
9 20963824-Table4 Mouse StemCell Fujimoto10 18genes GeneSigDB 4.600E-5 4.212E-3 3.071E-2 3.790E-2 2 17
10 14993899-TableS1 Human Futreal04 427genes ConsensusCancerGenes GeneSigDB 5.324E-5 4.387E-3 3.199E-2 4.387E-2 4 364
11 20963824-Table2 Mouse StemCell Fujimoto10 32genes GeneSigDB 8.540E-5 6.397E-3 4.665E-2
7.037E-2
 2 23
12 16288033-Table1 Human Prostate Joesting05 37genes GeneSigDB 1.565E-4 9.921E-3
7.234E-2
1.290E-1
 2 31
13 M1291 Candidate mammary tumorigenesis genes from the common insertion sites (CIS) of MMTV virus that induced breast tumors in mice. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.565E-4 9.921E-3
7.234E-2
1.290E-1
 2 31
14 14695345-Table1b Mouse Viral Politi04 40genes DownRegulated GeneSigDB 1.886E-4 1.046E-2
7.631E-2
1.554E-1
 2 34
15 M7790 Genes down-regulated in neutrophils: untreated versus LPS. MSigDB C7: Immunologic Signatures (v6.0) 2.159E-4 1.046E-2
7.631E-2
1.779E-1
 3 200
16 M4297 Genes up-regulated in comparison of naive CD8 T cells versus effector CD8 IL2RA [GeneID=3559] low T cells at. MSigDB C7: Immunologic Signatures (v6.0) 2.159E-4 1.046E-2
7.631E-2
1.779E-1
 3 200
17 M364 Genes down-regulated in macrophages differentiated in the presence of IL4 [GeneID=3565] and dexamethasone [PubChem=5743] for 5 days versus those subsequently treated with TGFB1 [GeneID=7040] for 24h. MSigDB C7: Immunologic Signatures (v6.0) 2.159E-4 1.046E-2
7.631E-2
1.779E-1
 3 200
18 M5895 Genes up-regulated by activation of WNT signaling through accumulation of beta catenin CTNNB1 [GeneID=1499]. MSigDB H: Hallmark Gene Sets (v6.0) 2.887E-4 1.313E-2
9.573E-2
2.379E-1
 2 42
19 M4389 Selected genes down-regulated in the TLX1 [GeneID=3195] Tet On iEBHX15-4 cells (pro-erythroblasts) at 12 h time point. MSigDB C2: CGP Curated Gene Sets (v6.0) 3.027E-4 1.313E-2
9.573E-2
2.494E-1
 2 43
20 M1758 Wnt target genes up-regulated after Cre-lox knockout of APC [GeneID=324] in the small intestine that require functional MYC [GeneID=4609]. MSigDB C2: CGP Curated Gene Sets (v6.0) 5.512E-4 2.271E-2
1.656E-1
4.542E-1
 2 58
21 M2456 Genes requiring MLL [GeneID=4297] for H3K4me3 and expression in MEF cells (embryonic fibroblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 6.339E-4 2.487E-2
1.814E-1
5.224E-1
 3 289
22 18927307-tableS4 Human Colon Allen08 124genes GeneSigDB 9.945E-4 3.725E-2
2.716E-1
8.195E-1
 2 78
23 M11288 Genes bearing H3K27me3 mark or whose promoters are bound by the polycomb proteins SUZ12 or EED [GeneID=23512;8726]; their DNA is methylated de novo in cancer. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.263E-3 4.526E-2
3.301E-1
1.000E0
 2 88
24 15297395-SuppTable4 Human Lymphoma Sriuranpong04 670genes Epithelium(N)Metaplastic/DisplasticLesions GeneSigDB 1.326E-3 4.551E-2
3.319E-1
1.000E0
 3 373
25 M2214 Genes down-regulated in CD4+ [GeneID=920] T lymphocytes after stimulation with prostaglandin E2 [PubChem=5280360]. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.463E-3 4.821E-2
3.516E-1
1.000E0
 3 386
26 M16734 Genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer) by ChIP-chip assay on a 12K CpG array (high-CpG-density promoters, HCP). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.532E-3 4.855E-2
3.540E-1
1.000E0
 2 97
Show 21 more annotations

14: Coexpression Atlas [Display Chart] 14 input genes in category / 1121 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 100 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 100 FaceBase_RNAseq 2.045E-11 2.292E-8 1.742E-7 2.292E-8 6 98
2 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 500 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 500 FaceBase_RNAseq 8.964E-9 5.024E-6 3.818E-5 1.005E-5 7 496
3 Facebase ST1 e8.5 NeuroEpith HindBrain 100 e8.5 NeuroEpith HindBrain top-relative-expression-ranked 100 FaceBase_ST1 1.712E-7 6.396E-5 4.861E-4 1.919E-4 4 81
4 PCBC ECTO blastocyst 500 Progenitor-Cell-Biology-Consortium induced-Ectoderm fromBlastocyst-derived-humanEmbryonicStemCells top-relative-expression-ranked 500 PCBC 3.198E-7 8.940E-5 6.794E-4 3.585E-4 6 490
5 PCBC ratio ECTO from-ESC vs ECTO from-plasmid cfr-2X-p05 Ectoderm Differentiated Cells-method NA vs Ectoderm Differentiated Cells-method plasmid-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 4.512E-7 8.940E-5 6.794E-4 5.058E-4 4 103
6 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Overall Top 200 Genes BrainMap 5.064E-7 8.940E-5 6.794E-4 5.677E-4 4 106
7 BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Inhibitory Top 200 Genes BrainMap BrainAtlas - Human / Mouse Linnarsson Neuron Neuron Subtype Inhibitory Top 200 Genes BrainMap 5.582E-7 8.940E-5 6.794E-4 6.258E-4 5 275
8 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 1000 K3 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 1000 k-means-cluster#3 FaceBase_RNAseq 6.659E-7 9.331E-5 7.092E-4 7.465E-4 5 285
9 PCBC ratio ECTO blastocyst vs ECTO fibroblast cfr-2X-p05 ECTO blastocyst vs ECTO fibroblast-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 8.331E-7 1.038E-4 7.886E-4 9.340E-4 4 120
10 PCBC ratio ECTO blastocyst vs ECTO bone marrow cfr-2X-p05 ECTO blastocyst vs ECTO bone marrow-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.087E-6 2.249E-4 1.709E-3 2.339E-3 4 151
11 Facebase RNAseq e10.5 Neural Epithelium Overlying Central Eminence 500 K2 FacebaseRNAseq e10.5 Neural Epithelium Overlying Central Eminence top-relative-expression-ranked 500 k-means-cluster#2 FaceBase_RNAseq 2.207E-6 2.249E-4 1.709E-3 2.474E-3 3 41
12 Facebase ST1 e9.5 OlfacPlacod 500 3 e9.5 OlfacPlacod top-relative-expression-ranked 500 3 FaceBase_ST1 2.970E-6 2.623E-4 1.994E-3 3.329E-3 4 165
13 Sample Type by Project: Shred 1/TCGA-Bladder/Urothelial Carcinoma/Muscle invasive urothelial carcinoma/5 Sample Type by Project: Shred 1/TCGA-Bladder/Urothelial Carcinoma/Muscle invasive urothelial carcinoma/5 TCGA-Bladder 3.042E-6 2.623E-4 1.994E-3 3.410E-3 4 166
14 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 Entopeduncular Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 Entopeduncular Top 200 Genes BrainMap 4.678E-6 3.746E-4 2.847E-3 5.244E-3 4 185
15 Facebase ST1 e8.5 NeuroEpith HindBrain 500 e8.5 NeuroEpith HindBrain top-relative-expression-ranked 500 FaceBase_ST1 5.604E-6 4.188E-4 3.183E-3 6.282E-3 5 440
16 Facebase ST1 e8.5 NeuroEpith HindBrain 250 e8.5 NeuroEpith HindBrain top-relative-expression-ranked 250 FaceBase_ST1 7.726E-6 5.413E-4 4.114E-3 8.661E-3 4 210
17 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 500 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 500 FaceBase_RNAseq 9.362E-6 5.686E-4 4.321E-3 1.049E-2 5 489
18 gudmap RNAseq e15.5 Mesangium 2500 K0 gudmap RNAseq e15.5 Mesangium 2500 K0 Gudmap RNAseq 9.819E-6 5.686E-4 4.321E-3 1.101E-2 3 67
19 Facebase RNAseq e10.5 Neural Epithelium Overlying Central Eminence 500 FacebaseRNAseq e10.5 Neural Epithelium Overlying Central Eminence top-relative-expression-ranked 500 FaceBase_RNAseq 1.013E-5 5.686E-4 4.321E-3 1.135E-2 5 497
20 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 SubstantiaNigra Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 SubstantiaNigra Top 200 Genes BrainMap 1.014E-5 5.686E-4 4.321E-3 1.137E-2 4 225
21 PCBC ratio ECTO from-ESC vs ECTO from-OSKM - NLT cfr-2X-p05 Ectoderm Differentiated Cells-reprogram NA vs Ectoderm Differentiated Cells-reprogram OSKM - NLT-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 1.614E-5 8.613E-4 6.546E-3 1.809E-2 3 79
22 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 Thalamus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 Thalamus Top 200 Genes BrainMap 1.765E-5 8.994E-4 6.835E-3 1.979E-2 4 259
23 BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 GlobusPallidus Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Inhibitory.subGroup8 Inhibitory.subGroup8 Subtype Inhibitory.subGroup8 GlobusPallidus Top 200 Genes BrainMap 1.903E-5 9.274E-4 7.048E-3 2.133E-2 4 264
24 ratio ECTO vs SC 500 K1 ratio induced-Ectoderm vs StemCell top-relative-expression-ranked 500 k-means-cluster#1 PCBC 2.499E-5 1.048E-3 7.967E-3 2.801E-2 4 283
25 PCBC ratio ECTO blastocyst vs ECTO amniotic fluid MSC cfr-2X-p05 ECTO blastocyst vs ECTO amniotic fluid MSC-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.750E-5 1.048E-3 7.967E-3 3.083E-2 4 290
26 PCBC ratio ECTO blastocyst vs ECTO UCB CD34+Z cfr-2X-p05 ECTO blastocyst vs ECTO UCB CD34+Z-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.901E-5 1.048E-3 7.967E-3 3.252E-2 4 294
27 Facebase RNAseq e8.5 Paraxial Mesoderm 100 FacebaseRNAseq e8.5 Paraxial Mesoderm top-relative-expression-ranked 100 FaceBase_RNAseq 2.988E-5 1.048E-3 7.967E-3 3.350E-2 3 97
28 Facebase RNAseq e8.5 Non-Floor Plate Neural Epithelium 100 FacebaseRNAseq e8.5 Non-Floor Plate Neural Epithelium top-relative-expression-ranked 100 FaceBase_RNAseq 3.081E-5 1.048E-3 7.967E-3 3.454E-2 3 98
29 Facebase RNAseq e9.5 Olfactory Placode 100 FacebaseRNAseq e9.5 Olfactory Placode top-relative-expression-ranked 100 FaceBase_RNAseq 3.081E-5 1.048E-3 7.967E-3 3.454E-2 3 98
30 gudmap developingLowerUrinaryTract e14.5 Genital tubercle F 1000 k3 DevelopingLowerUrinaryTract e14.5 Genital tubercle F emap-6706 k-means-cluster#3 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 3.081E-5 1.048E-3 7.967E-3 3.454E-2 3 98
31 Facebase RNAseq e10.5 Lateral Nasal Eminence 100 FacebaseRNAseq e10.5 Lateral Nasal Eminence top-relative-expression-ranked 100 FaceBase_RNAseq 3.176E-5 1.048E-3 7.967E-3 3.561E-2 3 99
32 PCBC ECTO fibroblast 100 Progenitor-Cell-Biology-Consortium induced-Ectoderm from inducedPluripotentialStemCells derived from from fibroblast top-relative-expression-ranked 100 PCBC 3.273E-5 1.048E-3 7.967E-3 3.669E-2 3 100
33 PCBC ratio ECTO vs SC 100 ratio induced-Ectoderm vs StemCell top-relative-expression-ranked 100 PCBC 3.273E-5 1.048E-3 7.967E-3 3.669E-2 3 100
34 PCBC ECTO 100 Progenitor-Cell-Biology-Consortium induced-Ectoderm top-relative-expression-ranked 100 PCBC 3.273E-5 1.048E-3 7.967E-3 3.669E-2 3 100
35 Facebase RNAseq e10.5 Neural Epithelium Overlying Central Eminence 100 FacebaseRNAseq e10.5 Neural Epithelium Overlying Central Eminence top-relative-expression-ranked 100 FaceBase_RNAseq 3.273E-5 1.048E-3 7.967E-3 3.669E-2 3 100
36 Facebase RNAseq e10.5 Neural Epithelium Overlying Central Eminence 1000 K5 FacebaseRNAseq e10.5 Neural Epithelium Overlying Central Eminence top-relative-expression-ranked 1000 k-means-cluster#5 FaceBase_RNAseq 3.372E-5 1.048E-3 7.968E-3 3.780E-2 3 101
37 Facebase ST1 e9.5 OlfacPlacod 500 5 e9.5 OlfacPlacod top-relative-expression-ranked 500 5 FaceBase_ST1 3.461E-5 1.048E-3 7.968E-3 3.879E-2 2 14
38 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Subtype eRgle Top 200 Genes GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC eRgl Subtype eRgle Top 200 Genes GSE76381_ESMoleculeCountsPMLog2 4.343E-5 1.281E-3 9.737E-3 4.869E-2 4 326
39 BrainMap BrainAtlas - Mouse McCarroll Cerebellum Cerebellum Overall Top 200 Genes BrainMap BrainAtlas - Mouse McCarroll Cerebellum Cerebellum Overall Top 200 Genes BrainMap 5.232E-5 1.504E-3 1.143E-2
5.865E-2
 3 117
40 PCBC ratio EB blastocyst vs EB bone marrow cfr-2X-p05 EB blastocyst vs EB bone marrow-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 5.791E-5 1.621E-3 1.232E-2
6.491E-2
 4 351
41 Sample Type by Project: Shred 1/TCGA-Stomach/Stomach Adenocarcinoma/Stomach Adenocarcinoma - Tubular/1/3 Sample Type by Project: Shred 1/TCGA-Stomach/Stomach Adenocarcinoma/Stomach Adenocarcinoma - Tubular/1/3 TCGA-Stomach 5.927E-5 1.621E-3 1.232E-2
6.644E-2
 3 122
42 Facebase RNAseq e10.5 Lateral Nasal Eminence 500 K3 FacebaseRNAseq e10.5 Lateral Nasal Eminence top-relative-expression-ranked 500 k-means-cluster#3 FaceBase_RNAseq 8.011E-5 2.138E-3 1.625E-2
8.980E-2
 3 135
43 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/mixed excitatory/Slc17a7 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Neuron/Neuron/mixed excitatory/Slc17a7 BrainMap 9.308E-5 2.427E-3 1.844E-2
1.043E-1
 3 142
44 Sample Type by Project: Shred 1/TCGA-Endometrium/Endometrial Adenocarcinoma/Mixed Serous and Endometrioid/1/3 Sample Type by Project: Shred 1/TCGA-Endometrium/Endometrial Adenocarcinoma/Mixed Serous and Endometrioid/1/3 TCGA-Endometrium 9.702E-5 2.472E-3 1.879E-2
1.088E-1
 3 144
45 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 40 GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Top 40 GSE76381_EmbryoMoleculeCountsPMLog2 1.031E-4 2.569E-3 1.953E-2
1.156E-1
 3 147
46 ratio EB vs SC 1000 K5 ratio EmbryoidBody vs StemCell top-relative-expression-ranked 1000 k-means-cluster#5 PCBC 1.139E-4 2.776E-3 2.110E-2
1.277E-1
 4 418
47 facebase RNAseq e8.5 NeuroEpith hindBrain 2500 K3 facebase RNAseq e8.5 NeuroEpith hindBrain 2500 K3 Gudmap RNAseq 1.231E-4 2.927E-3 2.225E-2
1.379E-1
 2 26
48 Facebase RNAseq e8.5 Hind Brain Neural Epithelium 500 K1 FacebaseRNAseq e8.5 Hind Brain Neural Epithelium top-relative-expression-ranked 500 k-means-cluster#1 FaceBase_RNAseq 1.253E-4 2.927E-3 2.225E-2
1.405E-1
 3 157
49 gudmap kidney P2 CapMes Crym k4 100 kidney P2 CapMes Crym k-means-cluster#4 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.328E-4 3.039E-3 2.310E-2
1.489E-1
 2 27
50 ratio ECTO vs SC 1000 K3 ratio induced-Ectoderm vs StemCell top-relative-expression-ranked 1000 k-means-cluster#3 PCBC 1.878E-4 4.070E-3 3.093E-2
2.106E-1
 4 476
Show 45 more annotations

15: Computational [Display Chart] 11 input genes in category / 107 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M17328 MORF MYC Neighborhood of MYC MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.125E-6 1.204E-4 6.325E-4 1.204E-4 4 79
2 M10328 MORF FLT1 Neighborhood of FLT1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.299E-6 3.905E-4 2.052E-3 7.810E-4 4 126
3 M1846 MODULE 220 Developmental processes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.529E-5 5.452E-4 2.865E-3 1.636E-3 5 333
4 M11486 MORF ESR1 Neighborhood of ESR1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.502E-5 6.693E-4 3.517E-3 2.677E-3 4 172
5 M14346 MORF ETV3 Neighborhood of ETV3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.934E-5 8.419E-4 4.424E-3 4.210E-3 3 64
6 M19723 MORF BCL2 Neighborhood of BCL2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.804E-5 1.213E-3 6.376E-3 7.280E-3 4 222
7 M4711 MORF JAG1 Neighborhood of JAG1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.243E-4 1.682E-3 8.837E-3 1.330E-2 3 94
8 M7497 MORF JAK3 Neighborhood of JAK3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.323E-4 1.682E-3 8.837E-3 1.416E-2 3 96
9 M18296 MORF TNFRSF25 Neighborhood of TNFRSF25 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.415E-4 1.682E-3 8.837E-3 1.514E-2 4 268
10 M18796 MORF CDC2L5 Neighborhood of CDC2L5 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.038E-4 4.238E-3 2.227E-2 4.320E-2 3 140
11 M3336 MORF LTK Neighborhood of LTK MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.659E-4 4.238E-3 2.227E-2 4.986E-2 3 147
12 M1006 MORF RAGE Neighborhood of RAGE MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 4.753E-4 4.238E-3 2.227E-2
5.086E-2
 3 148
13 M5671 MORF STK17A Neighborhood of STK17A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 7.250E-4 5.967E-3 3.136E-2
7.758E-2
 3 171
14 M2795 MORF BNIP1 Neighborhood of BNIP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.850E-4 7.528E-3 3.956E-2
1.054E-1
 3 190
15 M16071 MODULE 38 Placenta genes. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.147E-3 8.185E-3 4.301E-2
1.228E-1
 4 464
16 M3617 MORF LMO1 Neighborhood of LMO1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.300E-3 8.629E-3 4.534E-2
1.391E-1
 2 50
17 M2430 MORF RBBP8 Neighborhood of RBBP8 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.371E-3 8.629E-3 4.534E-2
1.467E-1
 3 213
18 M6229 MORF FDXR Neighborhood of FDXR MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.626E-3 9.667E-3
5.079E-2
1.740E-1
 3 226
19 M15921 MORF MT4 Neighborhood of MT4 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.074E-3 1.123E-2
5.900E-2
2.219E-1
 3 246
20 M13751 MODULE 123 Genes in the cancer module 123. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.099E-3 1.123E-2
5.900E-2
2.245E-1
 3 247
21 M18287 MORF PAX7 Neighborhood of PAX7 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 2.678E-3 1.364E-2
7.169E-2
2.865E-1
 3 269
22 M8621 MORF NOS2A Neighborhood of NOS2A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.348E-3 1.628E-2
8.556E-2
3.582E-1
 3 291
23 M4363 MORF ARL3 Neighborhood of ARL3 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.895E-3 1.812E-2
9.522E-2
4.168E-1
 3 307
24 M404 MORF ERCC2 Neighborhood of ERCC2 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 5.298E-3 2.362E-2
1.241E-1
5.669E-1
 2 102
25 M16604 MORF PRKACA Neighborhood of PRKACA MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.246E-3 2.673E-2
1.405E-1
6.683E-1
 2 111
26 M5177 MORF CASP10 Neighborhood of CASP10 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 6.918E-3 2.847E-2
1.496E-1
7.402E-1
 2 117
27 M6407 MORF FOSL1 Neighborhood of FOSL1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 8.679E-3 3.440E-2
1.807E-1
9.287E-1
 3 409
28 M14149 MORF RAP1A Neighborhood of RAP1A MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 9.650E-3 3.688E-2
1.938E-1
1.000E0
 2 139
29 M14596 MORF PML Neighborhood of PML MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.047E-2 3.862E-2
2.029E-1
1.000E0
 2 145
30 M5518 MORF RUNX1 Neighborhood of RUNX1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.117E-2 3.984E-2
2.093E-1
1.000E0
 2 150
31 M19243 MORF DDX11 Neighborhood of DDX11 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.204E-2 4.156E-2
2.184E-1
1.000E0
 2 156
32 M12979 MORF FANCG Neighborhood of FANCG MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.356E-2 4.533E-2
2.382E-1
1.000E0
 2 166
33 M6373 MORF NF1 Neighborhood of NF1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.403E-2 4.549E-2
2.390E-1
1.000E0
 2 169
34 M16012 MORF PPP2R5B Neighborhood of PPP2R5B MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.499E-2 4.718E-2
2.479E-1
1.000E0
 2 175
Show 29 more annotations

16: MicroRNA [Display Chart] 14 input genes in category / 523 annotations before applied cutoff / 72241 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 hsa-miR-185-5p:TargetScan hsa-miR-185-5p TargetScan 1.696E-7 8.868E-5 6.064E-4 8.868E-5 4 264
2 hsa-miR-194-5p:TargetScan hsa-miR-194-5p TargetScan 3.312E-5 8.662E-3
5.923E-2
 1.732E-2 3 330
3 hsa-miR-1289:PITA hsa-miR-1289:PITA TOP PITA 1.640E-4 2.383E-2
1.629E-1
8.578E-2
 2 98
4 hsa-miR-206:Functional MTI Functional MTI miRTarbase 2.540E-4 2.383E-2
1.629E-1
1.328E-1
 2 122
5 hsa-miR-214-5p:TargetScan hsa-miR-214-5p TargetScan 3.294E-4 2.383E-2
1.629E-1
1.723E-1
 2 139
6 hsa-miR-134-5p:TargetScan hsa-miR-134-5p TargetScan 3.438E-4 2.383E-2
1.629E-1
1.798E-1
 2 142
7 hsa-miR-4302:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 3.486E-4 2.383E-2
1.629E-1
1.823E-1
 2 143
8 CATGTAA,MIR-496:MSigDB CATGTAA,MIR-496:MSigDB MSigDB 4.578E-4 2.383E-2
1.629E-1
2.395E-1
 2 164
9 ATACTGT,MIR-144:MSigDB ATACTGT,MIR-144:MSigDB MSigDB 6.326E-4 2.383E-2
1.629E-1
3.309E-1
 2 193
10 hsa-miR-4270:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 7.981E-4 2.383E-2
1.629E-1
4.174E-1
 2 217
11 hsa-miR-6754-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.054E-4 2.383E-2
1.629E-1
4.212E-1
 2 218
12 hsa-miR-4441:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 8.127E-4 2.383E-2
1.629E-1
4.251E-1
 2 219
13 hsa-miR-342-3p:TargetScan hsa-miR-342-3p TargetScan 8.955E-4 2.383E-2
1.629E-1
4.684E-1
 2 230
14 hsa-miR-1248:PITA hsa-miR-1248:PITA TOP PITA 9.503E-4 2.383E-2
1.629E-1
4.970E-1
 2 237
15 hsa-miR-3148:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.007E-3 2.383E-2
1.629E-1
5.264E-1
 2 244
16 hsa-miR-532-3p:TargetScan hsa-miR-532-3p TargetScan 1.007E-3 2.383E-2
1.629E-1
5.264E-1
 2 244
17 hsa-miR-455-3p.2:TargetScan hsa-miR-455-3p.2 TargetScan 1.039E-3 2.383E-2
1.629E-1
5.436E-1
 2 248
18 hsa-let-7e*:mirSVR lowEffct hsa-let-7e*:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 1.107E-3 2.383E-2
1.629E-1
5.788E-1
 2 256
19 hsa-miR-329-3p:TargetScan hsa-miR-329-3p TargetScan 1.133E-3 2.383E-2
1.629E-1
5.923E-1
 2 259
20 hsa-miR-362-3p:TargetScan hsa-miR-362-3p TargetScan 1.133E-3 2.383E-2
1.629E-1
5.923E-1
 2 259
21 CGGTGTG,MIR-220:MSigDB CGGTGTG,MIR-220:MSigDB MSigDB 1.162E-3 2.383E-2
1.629E-1
6.079E-1
 1 6
22 hsa-miR-585:PITA hsa-miR-585:PITA TOP PITA 1.162E-3 2.383E-2
1.629E-1
6.079E-1
 1 6
23 TATTATA,MIR-374:MSigDB TATTATA,MIR-374:MSigDB MSigDB 1.194E-3 2.383E-2
1.629E-1
6.243E-1
 2 266
24 ACATTCC,MIR-206:MSigDB ACATTCC,MIR-206:MSigDB MSigDB 1.349E-3 2.383E-2
1.629E-1
7.055E-1
 2 283
25 ACATTCC,MIR-1:MSigDB ACATTCC,MIR-1:MSigDB MSigDB 1.349E-3 2.383E-2
1.629E-1
7.055E-1
 2 283
26 hsa-miR-4756-5p:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.377E-3 2.383E-2
1.629E-1
7.203E-1
 2 286
27 hsa-miR-1321:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.387E-3 2.383E-2
1.629E-1
7.253E-1
 2 287
28 hsa-miR-4739:Functional MTI (Weak) Functional MTI (Weak) miRTarbase 1.416E-3 2.383E-2
1.629E-1
7.403E-1
 2 290
29 hsa-miR-449a:PITA hsa-miR-449a:PITA TOP PITA 1.464E-3 2.383E-2
1.629E-1
7.657E-1
 2 295
30 hsa-miR-34c-5p:PITA hsa-miR-34c-5p:PITA TOP PITA 1.464E-3 2.383E-2
1.629E-1
7.657E-1
 2 295
31 hsa-miR-34a:PITA hsa-miR-34a:PITA TOP PITA 1.464E-3 2.383E-2
1.629E-1
7.657E-1
 2 295
32 hsa-miR-449b:PITA hsa-miR-449b:PITA TOP PITA 1.464E-3 2.383E-2
1.629E-1
7.657E-1
 2 295
33 hsa-miR-140-5p:TargetScan hsa-miR-140-5p TargetScan 1.503E-3 2.383E-2
1.629E-1
7.863E-1
 2 299
34 hsa-miR-566:mirSVR lowEffct hsa-miR-566:mirSVR nonconserved lowEffect-0.1-0.5 MicroRNA.org 1.676E-3 2.551E-2
1.745E-1
8.768E-1
 2 316
35 hsa-miR-217:TargetScan hsa-miR-217 TargetScan 1.750E-3 2.551E-2
1.745E-1
9.154E-1
 2 323
36 hsa-miR-338-3p:TargetScan hsa-miR-338-3p TargetScan 1.858E-3 2.551E-2
1.745E-1
9.720E-1
 2 333
37 hsa-miR-219a-5p:TargetScan hsa-miR-219a-5p TargetScan 1.869E-3 2.551E-2
1.745E-1
9.777E-1
 2 334
38 hsa-miR-31-5p:TargetScan hsa-miR-31-5p TargetScan 1.892E-3 2.551E-2
1.745E-1
9.893E-1
 2 336
39 hsa-miR-578:PITA hsa-miR-578:PITA TOP PITA 1.903E-3 2.551E-2
1.745E-1
9.951E-1
 2 337
40 hsa-miR-423-3p:TargetScan hsa-miR-423-3p TargetScan 2.130E-3 2.570E-2
1.758E-1
1.000E0
 1 11
41 hsa-miR-615-3p:TargetScan hsa-miR-615-3p TargetScan 2.130E-3 2.570E-2
1.758E-1
1.000E0
 1 11
42 hsa-miR-330-5p:TargetScan hsa-miR-330-5p TargetScan 2.274E-3 2.570E-2
1.758E-1
1.000E0
 2 369
43 hsa-miR-326:TargetScan hsa-miR-326 TargetScan 2.274E-3 2.570E-2
1.758E-1
1.000E0
 2 369
44 hsa-miR-1:PITA hsa-miR-1:PITA TOP PITA 2.298E-3 2.570E-2
1.758E-1
1.000E0
 2 371
45 hsa-miR-206:PITA hsa-miR-206:PITA TOP PITA 2.298E-3 2.570E-2
1.758E-1
1.000E0
 2 371
46 hsa-miR-613:PITA hsa-miR-613:PITA TOP PITA 2.310E-3 2.570E-2
1.758E-1
1.000E0
 2 372
47 hsa-miR-222-3p:TargetScan hsa-miR-222-3p TargetScan 2.359E-3 2.570E-2
1.758E-1
1.000E0
 2 376
48 hsa-miR-221-3p:TargetScan hsa-miR-221-3p TargetScan 2.359E-3 2.570E-2
1.758E-1
1.000E0
 2 376
49 hsa-miR-603:PITA hsa-miR-603:PITA TOP PITA 2.471E-3 2.637E-2
1.803E-1
1.000E0
 2 385
50 hsa-miR-133a-3p.1:TargetScan hsa-miR-133a-3p.1 TargetScan 2.849E-3 2.841E-2
1.943E-1
1.000E0
 2 414
Show 45 more annotations

17: Drug [Display Chart] 14 input genes in category / 2768 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID006122542 M-Hb Stitch 1.260E-14 3.487E-11 2.965E-10 3.487E-11 7 77
2 CID000003496 glyphosate Stitch 1.547E-13 2.141E-10 1.821E-9 4.283E-10 8 215
3 CID000007972 N-methylmorpholine Stitch 1.465E-11 1.352E-8 1.149E-7 4.055E-8 6 97
4 CID005326798 DB08181 Stitch 1.952E-9 1.351E-6 1.149E-5 5.403E-6 5 93
5 CID000020518 11-deoxojervine Stitch 4.856E-8 2.688E-5 2.286E-4 1.344E-4 5 176
6 CID000051605 fenoxycarb Stitch 1.360E-7 6.272E-5 5.334E-4 3.763E-4 4 80
7 CID000001200 AC1L1AXZ Stitch 5.951E-7 2.353E-4 2.001E-3 1.647E-3 3 28
8 3617 UP Bromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 5.021E-6 1.395E-3 1.186E-2 1.390E-2 4 197
9 4266 UP Medrysone [2668-66-8]; Up 200; 11.6uM; PC3; HT HG-U133A Broad Institute CMAP Up 5.021E-6 1.395E-3 1.186E-2 1.390E-2 4 197
10 3795 UP alpha-Santonin [481-06-1]; Up 200; 16.2uM; PC3; HT HG-U133A Broad Institute CMAP Up 5.331E-6 1.395E-3 1.186E-2 1.476E-2 4 200
11 CID006444175 Ra X Peptide Stitch 5.545E-6 1.395E-3 1.186E-2 1.535E-2 3 58
12 ctd:D000079 Acetaldehyde CTD 7.772E-6 1.793E-3 1.524E-2 2.151E-2 4 220
13 CID000006956 phthalamide Stitch 1.520E-5 3.237E-3 2.753E-2 4.209E-2 3 81
14 CID000139622 difluoroboron Stitch 1.696E-5 3.354E-3 2.852E-2 4.695E-2 3 84
15 CID005289552 alpha-D-glucose 1-phosphate 6-vanadate Stitch 1.951E-5 3.600E-3 3.061E-2
5.399E-2
 3 88
16 CID004369434 2brn Stitch 2.694E-5 4.660E-3 3.963E-2
7.456E-2
 3 98
17 ctd:C061365 flusilazole CTD 3.225E-5 5.251E-3 4.465E-2
8.927E-2
 4 316
18 CID005287574 anad Stitch 3.646E-5 5.607E-3 4.768E-2
1.009E-1
 2 15
19 CID000018879 rhombic Stitch 4.016E-5 5.851E-3 4.975E-2
1.112E-1
 3 112
20 ctd:C409722 hexaconazole CTD 4.935E-5 6.667E-3
5.669E-2
1.366E-1
 3 120
21 CID000492400 NVP & EFV Stitch 5.058E-5 6.667E-3
5.669E-2
1.400E-1
 3 121
22 CID000005307 A19413 Stitch 6.408E-5 8.062E-3
6.856E-2
1.774E-1
 3 131
23 CID006327182 tellurium Stitch 6.703E-5 8.067E-3
6.860E-2
1.856E-1
 3 133
24 CID000337220 NSC354319 Stitch 7.278E-5 8.394E-3
7.137E-2
2.014E-1
 2 21
25 ctd:C007076 citral CTD 9.555E-5 1.034E-2
8.795E-2
2.645E-1
 2 24
26 CID004630067 AC1NDQQ3 Stitch 1.038E-4 1.034E-2
8.795E-2
2.874E-1
 2 25
27 CID005287596 RWJ-56423 Stitch 1.124E-4 1.034E-2
8.795E-2
3.112E-1
 2 26
28 CID000008204 dodine Stitch 1.124E-4 1.034E-2
8.795E-2
3.112E-1
 2 26
29 CID000439929 phenanthrene-3,4-diol Stitch 1.307E-4 1.034E-2
8.795E-2
3.617E-1
 2 28
30 CID000050896 Verdict Stitch 1.403E-4 1.034E-2
8.795E-2
3.884E-1
 2 29
31 2700 UP 2-propylpentanoic acid; Up 200; 500uM; HL60; HT HG-U133A Broad Institute CMAP Up 1.928E-4 1.034E-2
8.795E-2
5.336E-1
 3 190
32 7486 UP CP-319743 [172078-87-4]; Up 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.958E-4 1.034E-2
8.795E-2
5.419E-1
 3 191
33 6479 UP Ethynodiol diacetate [297-76-7]; Up 200; 10.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 1.958E-4 1.034E-2
8.795E-2
5.419E-1
 3 191
34 318 UP LY294002; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.019E-4 1.034E-2
8.795E-2
5.588E-1
 3 193
35 5610 UP Carbetapentane citrate [23142-01-0]; Up 200; 7.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 2.050E-4 1.034E-2
8.795E-2
5.673E-1
 3 194
36 3988 DN Cinchonine [118-10-5]; Down 200; 13.6uM; PC3; HT HG-U133A Broad Institute CMAP Down 2.050E-4 1.034E-2
8.795E-2
5.673E-1
 3 194
37 5277 UP Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT HG-U133A Broad Institute CMAP Up 2.112E-4 1.034E-2
8.795E-2
5.847E-1
 3 196
38 2430 UP Hydroxytacrine maleate (R,S) [118909-22-1]; Up 200; 12.2uM; HL60; HT HG-U133A Broad Institute CMAP Up 2.112E-4 1.034E-2
8.795E-2
5.847E-1
 3 196
39 5666 UP Naringin hydrate [11032-30-7]; Up 200; 6.6uM; MCF7; HT HG-U133A Broad Institute CMAP Up 2.112E-4 1.034E-2
8.795E-2
5.847E-1
 3 196
40 2742 UP Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; HL60; HT HG-U133A Broad Institute CMAP Up 2.112E-4 1.034E-2
8.795E-2
5.847E-1
 3 196
41 4629 UP Droperidol [548-73-2]; Up 200; 10.6uM; PC3; HT HG-U133A Broad Institute CMAP Up 2.144E-4 1.034E-2
8.795E-2
5.936E-1
 3 197
42 6705 UP Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; PC3; HT HG-U133A Broad Institute CMAP Up 2.144E-4 1.034E-2
8.795E-2
5.936E-1
 3 197
43 4754 UP PNU-0230031 [267429-39-0]; Up 200; 10uM; MCF7; HT HG-U133A Broad Institute CMAP Up 2.144E-4 1.034E-2
8.795E-2
5.936E-1
 3 197
44 7012 UP Chloroquine diphosphate [50-63-5]; Up 200; 7.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
45 2715 UP Pridinol methanesulfonate salt [6856-31-1]; Up 200; 10.2uM; HL60; HT HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
46 4214 UP Propantheline bromide [50-34-0]; Up 200; 9uM; PC3; HT HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
47 3778 UP Indapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
48 2512 UP Anabasine [494-52-0]; Up 200; 24.6uM; HL60; HT HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
49 3390 UP Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
50 316 UP flufenamic acid; Up 200; 10uM; MCF7; HG-U133A Broad Institute CMAP Up 2.177E-4 1.034E-2
8.795E-2
6.025E-1
 3 198
Show 45 more annotations

18: Disease [Display Chart] 14 input genes in category / 841 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C3489529 Tooth Agenesis, Familial DisGeNET Curated 2.052E-9 1.726E-6 1.262E-5 1.726E-6 3 4
2 C0000846 Agenesis DisGeNET BeFree 1.016E-8 4.272E-6 3.124E-5 8.545E-6 5 92
3 C0399352 Developmental absence of tooth DisGeNET Curated 1.124E-7 2.276E-5 1.664E-4 9.454E-5 3 12
4 C4280640 Retrusion of upper jaw bones DisGeNET Curated 2.436E-7 2.276E-5 1.664E-4 2.049E-4 4 66
5 C4082243 Maxillary retrognathia DisGeNET Curated 2.436E-7 2.276E-5 1.664E-4 2.049E-4 4 66
6 C0240310 Hypoplasia of the maxilla DisGeNET Curated 2.436E-7 2.276E-5 1.664E-4 2.049E-4 4 66
7 C4280641 Hypotrophic maxilla DisGeNET Curated 2.436E-7 2.276E-5 1.664E-4 2.049E-4 4 66
8 C4280643 Decreased projection of maxilla DisGeNET Curated 2.436E-7 2.276E-5 1.664E-4 2.049E-4 4 66
9 C4280642 Deficiency of upper jaw bones DisGeNET Curated 2.436E-7 2.276E-5 1.664E-4 2.049E-4 4 66
10 OMIN:106600 TOOTH AGENESIS, SELECTIVE, 1; STHAG1 OMIM 6.931E-7 5.829E-5 4.262E-4 5.829E-4 2 2
11 C4280619 Missing more than six teeth DisGeNET Curated 7.829E-7 5.986E-5 4.377E-4 6.584E-4 3 22
12 C0338503 Septo-Optic Dysplasia DisGeNET Curated 1.028E-6 7.204E-5 5.268E-4 8.645E-4 3 24
13 C4082304 Oligodontia DisGeNET Curated 1.483E-6 9.595E-5 7.016E-4 1.247E-3 3 27
14 OMIN:268220 RHABDOMYOSARCOMA 2; RMS2 OMIM 2.078E-6 1.165E-4 8.521E-4 1.748E-3 2 3
15 cv:C0206655 Rhabdomyosarcoma alveolar Clinical Variations 2.078E-6 1.165E-4 8.521E-4 1.748E-3 2 3
16 C4280392 Hypotrophic nose DisGeNET Curated 6.921E-6 3.234E-4 2.365E-3 5.820E-3 2 5
17 C0685684 Congenital hypoplasia of nose DisGeNET Curated 6.921E-6 3.234E-4 2.365E-3 5.820E-3 2 5
18 C4024159 Aplasia/Hypoplasia involving the nose DisGeNET Curated 6.921E-6 3.234E-4 2.365E-3 5.820E-3 2 5
19 C3495417 Hemifacial microsomia DisGeNET BeFree 1.038E-5 4.593E-4 3.358E-3 8.726E-3 2 6
20 C4280612 Decreased width of tooth DisGeNET Curated 1.622E-5 6.820E-4 4.987E-3 1.364E-2 3 59
21 C4280611 Decreased size of teeth DisGeNET Curated 1.884E-5 7.075E-4 5.174E-3 1.584E-2 3 62
22 C0240340 Microdontia (disorder) DisGeNET Curated 1.884E-5 7.075E-4 5.174E-3 1.584E-2 3 62
23 C0154823 Retinal defect DisGeNET BeFree 1.935E-5 7.075E-4 5.174E-3 1.627E-2 2 8
24 C0039101 synovial sarcoma DisGeNET Curated 2.386E-5 8.050E-4 5.887E-3 2.007E-2 4 208
25 C0265240 Goldenhar Syndrome DisGeNET Curated 2.487E-5 8.050E-4 5.887E-3 2.091E-2 2 9
26 C0206655 Alveolar rhabdomyosarcoma DisGeNET Curated 2.489E-5 8.050E-4 5.887E-3 2.093E-2 3 68
27 C1456781 Benign melanocytic nevus DisGeNET BeFree 2.601E-5 8.100E-4 5.923E-3 2.187E-2 3 69
28 C1321884 Atresia of vagina DisGeNET Curated 3.107E-5 9.331E-4 6.823E-3 2.613E-2 2 10
29 C0027960 Nevus DisGeNET Curated 3.759E-5 1.064E-3 7.780E-3 3.161E-2 3 78
30 cv:CN120488 Anophthalmia/Microphthalmia Clinical Variations 3.795E-5 1.064E-3 7.780E-3 3.192E-2 2 11
31 C0178879 Urinary tract obstruction DisGeNET BeFree 5.377E-5 1.459E-3 1.067E-2 4.522E-2 2 13
32 C0750929 Arnold-Chiari Malformation, Type I DisGeNET Curated 6.270E-5 1.648E-3 1.205E-2
5.273E-2
 2 14
33 C0020608 Hypodontia DisGeNET Curated 6.995E-5 1.783E-3 1.304E-2
5.883E-2
 3 96
34 C0080233 Tooth Loss DisGeNET BeFree 7.231E-5 1.789E-3 1.308E-2
6.081E-2
 2 15
35 C0344559 Irido-corneo-trabecular dysgenesis (disorder) DisGeNET Curated 9.357E-5 2.248E-3 1.644E-2
7.869E-2
 2 17
36 C0003516 Aortopulmonary Septal Defect DisGeNET BeFree 1.175E-4 2.746E-3 2.008E-2
9.884E-2
 2 19
37 C0003076 Aniridia DisGeNET Curated 1.585E-4 3.603E-3 2.635E-2
1.333E-1
 2 22
38 C0027708 Nephroblastoma DisGeNET Curated 1.707E-4 3.649E-3 2.668E-2
1.435E-1
 4 345
39 C4072849 Scapular weakness DisGeNET Curated 1.735E-4 3.649E-3 2.668E-2
1.460E-1
 2 23
40 C0240953 Winged scapula DisGeNET Curated 1.735E-4 3.649E-3 2.668E-2
1.460E-1
 2 23
41 C0541764 Delayed bone age DisGeNET Curated 1.967E-4 4.034E-3 2.950E-2
1.654E-1
 3 136
42 C4021813 Oral cleft DisGeNET Curated 2.226E-4 4.457E-3 3.259E-2
1.872E-1
 2 26
43 C0220611 childhood rhabdomyosarcoma DisGeNET BeFree 2.403E-4 4.700E-3 3.437E-2
2.021E-1
 2 27
44 C0035412 Rhabdomyosarcoma DisGeNET Curated 2.758E-4 5.271E-3 3.854E-2
2.319E-1
 4 391
45 C0810364 Cleft Lip with or without Cleft Palate DisGeNET BeFree 2.974E-4 5.557E-3 4.064E-2
2.501E-1
 2 30
46 C0242343 Panhypopituitarism DisGeNET Curated 4.057E-4 6.605E-3 4.830E-2
3.412E-1
 2 35
47 C0041207 Truncus Arteriosus, Persistent DisGeNET Curated 4.537E-4 6.605E-3 4.830E-2
3.816E-1
 2 37
48 C0376634 Craniofacial Abnormalities DisGeNET Curated 4.705E-4 6.605E-3 4.830E-2
3.957E-1
 3 183
49 C0013575 Ectodermal Dysplasia DisGeNET Curated 5.043E-4 6.605E-3 4.830E-2
4.241E-1
 2 39
50 C0027962 Melanocytic nevus DisGeNET Curated 5.749E-4 6.605E-3 4.830E-2
4.835E-1
 3 196
Show 45 more annotations