1: GO: Molecular Function [Display Chart]
35 input genes in category / 76 annotations before applied cutoff / 18661 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
GO:0005085
|
guanyl-nucleotide exchange factor activity
|
|
1.286E-16
|
9.774E-15
|
4.803E-14
|
9.774E-15
|
14
|
306
|
|
2
|
GO:0003924
|
GTPase activity
|
|
3.348E-13
|
1.272E-11
|
6.252E-11
|
2.544E-11
|
11
|
236
|
|
3
|
GO:0005089
|
Rho guanyl-nucleotide exchange factor activity
|
|
1.707E-12
|
4.181E-11
|
2.055E-10
|
1.298E-10
|
8
|
80
|
|
4
|
GO:0005525
|
GTP binding
|
|
2.200E-12
|
4.181E-11
|
2.055E-10
|
1.672E-10
|
12
|
378
|
|
5
|
GO:0032561
|
guanyl ribonucleotide binding
|
|
4.148E-12
|
5.410E-11
|
2.659E-10
|
3.152E-10
|
12
|
399
|
|
6
|
GO:0019001
|
guanyl nucleotide binding
|
|
4.271E-12
|
5.410E-11
|
2.659E-10
|
3.246E-10
|
12
|
400
|
|
7
|
GO:0017048
|
Rho GTPase binding
|
|
2.265E-10
|
2.459E-9
|
1.208E-8
|
1.721E-8
|
7
|
87
|
|
8
|
GO:0005088
|
Ras guanyl-nucleotide exchange factor activity
|
|
3.239E-10
|
3.077E-9
|
1.512E-8
|
2.461E-8
|
9
|
232
|
|
9
|
GO:0017016
|
Ras GTPase binding
|
|
1.756E-9
|
1.482E-8
|
7.286E-8
|
1.334E-7
|
9
|
281
|
|
10
|
GO:0031267
|
small GTPase binding
|
|
3.206E-9
|
2.436E-8
|
1.197E-7
|
2.436E-7
|
9
|
301
|
|
11
|
GO:0051020
|
GTPase binding
|
|
6.601E-9
|
4.561E-8
|
2.241E-7
|
5.017E-7
|
9
|
327
|
|
12
|
GO:0051022
|
Rho GDP-dissociation inhibitor binding
|
|
6.028E-8
|
3.818E-7
|
1.876E-6
|
4.582E-6
|
3
|
5
|
|
13
|
GO:0051021
|
GDP-dissociation inhibitor binding
|
|
1.204E-7
|
7.040E-7
|
3.460E-6
|
9.152E-6
|
3
|
6
|
|
14
|
GO:0017124
|
SH3 domain binding
|
|
3.177E-6
|
1.725E-5
|
8.475E-5
|
2.414E-4
|
5
|
123
|
|
15
|
GO:0030695
|
GTPase regulator activity
|
|
2.246E-5
|
1.138E-4
|
5.592E-4
|
1.707E-3
|
6
|
312
|
|
16
|
GO:0060589
|
nucleoside-triphosphatase regulator activity
|
|
3.882E-5
|
1.844E-4
|
9.063E-4
|
2.951E-3
|
6
|
344
|
|
17
|
GO:0048365
|
Rac GTPase binding
|
|
6.599E-5
|
2.950E-4
|
1.450E-3
|
5.015E-3
|
3
|
42
|
|
18
|
GO:0005096
|
GTPase activator activity
|
|
1.731E-4
|
7.311E-4
|
3.593E-3
|
1.316E-2
|
5
|
283
|
|
19
|
GO:0030971
|
receptor tyrosine kinase binding
|
|
1.922E-4
|
7.689E-4
|
3.779E-3
|
1.461E-2
|
3
|
60
|
|
20
|
GO:1990782
|
protein tyrosine kinase binding
|
|
2.551E-4
|
9.692E-4
|
4.763E-3
|
1.938E-2
|
3
|
66
|
|
21
|
GO:0031996
|
thioesterase binding
|
|
3.066E-4
|
1.110E-3
|
5.453E-3
|
2.330E-2
|
2
|
14
|
|
22
|
GO:0030742
|
GTP-dependent protein binding
|
|
7.710E-4
|
2.664E-3
|
1.309E-2
|
5.860E-2
|
2
|
22
|
|
23
|
GO:0034191
|
apolipoprotein A-I receptor binding
|
|
7.482E-3
|
2.472E-2
|
1.215E-1
|
5.686E-1
|
1
|
4
|
|
24
|
GO:0034190
|
apolipoprotein receptor binding
|
|
1.306E-2
|
4.135E-2
|
2.032E-1
|
9.924E-1
|
1
|
7
|
|
25
|
GO:0042608
|
T cell receptor binding
|
|
1.491E-2
|
4.532E-2
|
2.227E-1
|
1.000E0
|
1
|
8
|
Show 20 more annotations
|
2: GO: Biological Process [Display Chart]
35 input genes in category / 1062 annotations before applied cutoff / 18623 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
GO:0051056
|
regulation of small GTPase mediated signal transduction
|
|
1.699E-18
|
1.804E-15
|
1.361E-14
|
1.804E-15
|
15
|
295
|
|
2
|
GO:0007265
|
Ras protein signal transduction
|
|
3.607E-10
|
1.683E-7
|
1.270E-6
|
3.830E-7
|
10
|
333
|
|
3
|
GO:0007266
|
Rho protein signal transduction
|
|
5.313E-10
|
1.683E-7
|
1.270E-6
|
5.643E-7
|
8
|
162
|
|
4
|
GO:0007596
|
blood coagulation
|
|
8.328E-10
|
1.683E-7
|
1.270E-6
|
8.844E-7
|
10
|
363
|
|
5
|
GO:0050817
|
coagulation
|
|
9.506E-10
|
1.683E-7
|
1.270E-6
|
1.010E-6
|
10
|
368
|
|
6
|
GO:0007599
|
hemostasis
|
|
9.506E-10
|
1.683E-7
|
1.270E-6
|
1.010E-6
|
10
|
368
|
|
7
|
GO:0030031
|
cell projection assembly
|
|
4.855E-9
|
7.365E-7
|
5.558E-6
|
5.156E-6
|
10
|
436
|
|
8
|
GO:0051057
|
positive regulation of small GTPase mediated signal transduction
|
|
2.257E-8
|
2.977E-6
|
2.246E-5
|
2.397E-5
|
5
|
46
|
|
9
|
GO:1900024
|
regulation of substrate adhesion-dependent cell spreading
|
|
2.523E-8
|
2.977E-6
|
2.246E-5
|
2.679E-5
|
5
|
47
|
|
10
|
GO:0010810
|
regulation of cell-substrate adhesion
|
|
4.364E-8
|
4.635E-6
|
3.497E-5
|
4.635E-5
|
7
|
184
|
|
11
|
GO:0046578
|
regulation of Ras protein signal transduction
|
|
7.731E-8
|
7.464E-6
|
5.632E-5
|
8.211E-5
|
7
|
200
|
|
12
|
GO:0031589
|
cell-substrate adhesion
|
|
1.148E-7
|
1.016E-5
|
7.667E-5
|
1.219E-4
|
8
|
322
|
|
13
|
GO:1900026
|
positive regulation of substrate adhesion-dependent cell spreading
|
|
3.620E-7
|
2.869E-5
|
2.165E-4
|
3.845E-4
|
4
|
32
|
|
14
|
GO:0090630
|
activation of GTPase activity
|
|
3.782E-7
|
2.869E-5
|
2.165E-4
|
4.016E-4
|
5
|
80
|
|
15
|
GO:0034446
|
substrate adhesion-dependent cell spreading
|
|
5.435E-7
|
3.848E-5
|
2.903E-4
|
5.772E-4
|
5
|
86
|
|
16
|
GO:0048013
|
ephrin receptor signaling pathway
|
|
6.097E-7
|
4.047E-5
|
3.054E-4
|
6.475E-4
|
5
|
88
|
|
17
|
GO:0046579
|
positive regulation of Ras protein signal transduction
|
|
9.104E-7
|
5.572E-5
|
4.204E-4
|
9.668E-4
|
4
|
40
|
|
18
|
GO:0045785
|
positive regulation of cell adhesion
|
|
9.443E-7
|
5.572E-5
|
4.204E-4
|
1.003E-3
|
8
|
425
|
|
19
|
GO:0010770
|
positive regulation of cell morphogenesis involved in differentiation
|
|
1.062E-6
|
5.938E-5
|
4.481E-4
|
1.128E-3
|
6
|
183
|
|
20
|
GO:0030335
|
positive regulation of cell migration
|
|
1.333E-6
|
7.078E-5
|
5.341E-4
|
1.416E-3
|
8
|
445
|
|
21
|
GO:2000147
|
positive regulation of cell motility
|
|
1.653E-6
|
8.360E-5
|
6.308E-4
|
1.756E-3
|
8
|
458
|
|
22
|
GO:0051272
|
positive regulation of cellular component movement
|
|
2.005E-6
|
9.409E-5
|
7.099E-4
|
2.129E-3
|
8
|
470
|
|
23
|
GO:0038093
|
Fc receptor signaling pathway
|
|
2.116E-6
|
9.409E-5
|
7.099E-4
|
2.247E-3
|
6
|
206
|
|
24
|
GO:0050863
|
regulation of T cell activation
|
|
2.127E-6
|
9.409E-5
|
7.099E-4
|
2.259E-3
|
7
|
327
|
|
25
|
GO:0040017
|
positive regulation of locomotion
|
|
2.238E-6
|
9.409E-5
|
7.099E-4
|
2.376E-3
|
8
|
477
|
|
26
|
GO:0035023
|
regulation of Rho protein signal transduction
|
|
2.303E-6
|
9.409E-5
|
7.099E-4
|
2.446E-3
|
5
|
115
|
|
27
|
GO:1903037
|
regulation of leukocyte cell-cell adhesion
|
|
2.807E-6
|
1.104E-4
|
8.332E-4
|
2.981E-3
|
7
|
341
|
|
28
|
GO:0034332
|
adherens junction organization
|
|
2.960E-6
|
1.110E-4
|
8.379E-4
|
3.143E-3
|
5
|
121
|
|
29
|
GO:0007015
|
actin filament organization
|
|
3.032E-6
|
1.110E-4
|
8.379E-4
|
3.220E-3
|
7
|
345
|
|
30
|
GO:0034110
|
regulation of homotypic cell-cell adhesion
|
|
3.211E-6
|
1.137E-4
|
8.576E-4
|
3.410E-3
|
7
|
348
|
|
31
|
GO:0045216
|
cell-cell junction organization
|
|
3.999E-6
|
1.370E-4
|
1.034E-3
|
4.247E-3
|
6
|
230
|
|
32
|
GO:0030032
|
lamellipodium assembly
|
|
4.420E-6
|
1.467E-4
|
1.107E-3
|
4.694E-3
|
4
|
59
|
|
33
|
GO:0051017
|
actin filament bundle assembly
|
|
4.884E-6
|
1.572E-4
|
1.186E-3
|
5.187E-3
|
5
|
134
|
|
34
|
GO:0010769
|
regulation of cell morphogenesis involved in differentiation
|
|
5.158E-6
|
1.611E-4
|
1.216E-3
|
5.478E-3
|
7
|
374
|
|
35
|
GO:0061572
|
actin filament bundle organization
|
|
5.640E-6
|
1.711E-4
|
1.291E-3
|
5.990E-3
|
5
|
138
|
|
36
|
GO:0034330
|
cell junction organization
|
|
7.729E-6
|
2.280E-4
|
1.721E-3
|
8.209E-3
|
6
|
258
|
|
37
|
GO:0034109
|
homotypic cell-cell adhesion
|
|
8.270E-6
|
2.316E-4
|
1.747E-3
|
8.783E-3
|
7
|
402
|
|
38
|
GO:0045576
|
mast cell activation
|
|
8.285E-6
|
2.316E-4
|
1.747E-3
|
8.799E-3
|
4
|
69
|
|
39
|
GO:0048041
|
focal adhesion assembly
|
|
9.820E-6
|
2.607E-4
|
1.967E-3
|
1.043E-2
|
4
|
72
|
|
40
|
GO:0007045
|
cell-substrate adherens junction assembly
|
|
9.820E-6
|
2.607E-4
|
1.967E-3
|
1.043E-2
|
4
|
72
|
|
41
|
GO:0097581
|
lamellipodium organization
|
|
1.218E-5
|
3.155E-4
|
2.381E-3
|
1.294E-2
|
4
|
76
|
|
42
|
GO:0022407
|
regulation of cell-cell adhesion
|
|
1.281E-5
|
3.239E-4
|
2.444E-3
|
1.360E-2
|
7
|
430
|
|
43
|
GO:0002275
|
myeloid cell activation involved in immune response
|
|
1.494E-5
|
3.689E-4
|
2.784E-3
|
1.586E-2
|
4
|
80
|
|
44
|
GO:1902745
|
positive regulation of lamellipodium organization
|
|
1.535E-5
|
3.705E-4
|
2.795E-3
|
1.630E-2
|
3
|
26
|
|
45
|
GO:0051249
|
regulation of lymphocyte activation
|
|
1.599E-5
|
3.773E-4
|
2.847E-3
|
1.698E-2
|
7
|
445
|
|
46
|
GO:0034333
|
adherens junction assembly
|
|
1.648E-5
|
3.804E-4
|
2.870E-3
|
1.750E-2
|
4
|
82
|
|
47
|
GO:0060491
|
regulation of cell projection assembly
|
|
1.739E-5
|
3.929E-4
|
2.965E-3
|
1.847E-2
|
5
|
174
|
|
48
|
GO:0002244
|
hematopoietic progenitor cell differentiation
|
|
1.788E-5
|
3.955E-4
|
2.984E-3
|
1.898E-2
|
5
|
175
|
|
49
|
GO:0042058
|
regulation of epidermal growth factor receptor signaling pathway
|
|
1.900E-5
|
4.117E-4
|
3.107E-3
|
2.017E-2
|
4
|
85
|
|
50
|
GO:1901184
|
regulation of ERBB signaling pathway
|
|
2.179E-5
|
4.617E-4
|
3.484E-3
|
2.314E-2
|
4
|
88
|
Show 45 more annotations
|
3: GO: Cellular Component [Display Chart]
35 input genes in category / 129 annotations before applied cutoff / 19061 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
GO:0005912
|
adherens junction
|
|
6.081E-10
|
5.900E-8
|
3.210E-7
|
7.844E-8
|
11
|
484
|
|
2
|
GO:0005925
|
focal adhesion
|
|
1.436E-9
|
5.900E-8
|
3.210E-7
|
1.853E-7
|
10
|
393
|
|
3
|
GO:0005924
|
cell-substrate adherens junction
|
|
1.622E-9
|
5.900E-8
|
3.210E-7
|
2.093E-7
|
10
|
398
|
|
4
|
GO:0030055
|
cell-substrate junction
|
|
1.829E-9
|
5.900E-8
|
3.210E-7
|
2.360E-7
|
10
|
403
|
|
5
|
GO:0031252
|
cell leading edge
|
|
2.473E-8
|
6.381E-7
|
3.472E-6
|
3.190E-6
|
9
|
389
|
|
6
|
GO:0030027
|
lamellipodium
|
|
1.022E-6
|
2.197E-5
|
1.195E-4
|
1.318E-4
|
6
|
186
|
|
7
|
GO:0030426
|
growth cone
|
|
1.933E-5
|
2.841E-4
|
1.546E-3
|
2.493E-3
|
5
|
182
|
|
8
|
GO:0000322
|
storage vacuole
|
|
1.961E-5
|
2.841E-4
|
1.546E-3
|
2.529E-3
|
2
|
4
|
|
9
|
GO:0015629
|
actin cytoskeleton
|
|
2.126E-5
|
2.841E-4
|
1.546E-3
|
2.742E-3
|
7
|
476
|
|
10
|
GO:0030427
|
site of polarized growth
|
|
2.202E-5
|
2.841E-4
|
1.546E-3
|
2.841E-3
|
5
|
187
|
|
11
|
GO:0005884
|
actin filament
|
|
2.583E-5
|
3.029E-4
|
1.648E-3
|
3.332E-3
|
4
|
94
|
|
12
|
GO:0005826
|
actomyosin contractile ring
|
|
4.891E-5
|
5.257E-4
|
2.861E-3
|
6.309E-3
|
2
|
6
|
|
13
|
GO:0030496
|
midbody
|
|
1.125E-4
|
1.082E-3
|
5.890E-3
|
1.451E-2
|
4
|
137
|
|
14
|
GO:0005938
|
cell cortex
|
|
1.175E-4
|
1.082E-3
|
5.890E-3
|
1.515E-2
|
5
|
266
|
|
15
|
GO:0032153
|
cell division site
|
|
1.550E-4
|
1.211E-3
|
6.588E-3
|
2.000E-2
|
3
|
57
|
|
16
|
GO:0032155
|
cell division site part
|
|
1.550E-4
|
1.211E-3
|
6.588E-3
|
2.000E-2
|
3
|
57
|
|
17
|
GO:0031256
|
leading edge membrane
|
|
1.596E-4
|
1.211E-3
|
6.588E-3
|
2.058E-2
|
4
|
150
|
|
18
|
GO:0070938
|
contractile ring
|
|
2.137E-4
|
1.532E-3
|
8.333E-3
|
2.757E-2
|
2
|
12
|
|
19
|
GO:0001726
|
ruffle
|
|
2.520E-4
|
1.689E-3
|
9.191E-3
|
3.250E-2
|
4
|
169
|
|
20
|
GO:0030864
|
cortical actin cytoskeleton
|
|
2.619E-4
|
1.689E-3
|
9.191E-3
|
3.379E-2
|
3
|
68
|
|
21
|
GO:0099568
|
cytoplasmic region
|
|
2.980E-4
|
1.831E-3
|
9.961E-3
|
3.845E-2
|
5
|
325
|
|
22
|
GO:0032587
|
ruffle membrane
|
|
4.880E-4
|
2.862E-3
|
1.557E-2
|
6.296E-2
|
3
|
84
|
|
23
|
GO:0030863
|
cortical cytoskeleton
|
|
7.430E-4
|
4.167E-3
|
2.267E-2
|
9.584E-2
|
3
|
97
|
|
24
|
GO:0031941
|
filamentous actin
|
|
1.117E-3
|
6.004E-3
|
3.267E-2
|
1.441E-1
|
2
|
27
|
|
25
|
GO:0051233
|
spindle midzone
|
|
1.380E-3
|
7.119E-3
|
3.873E-2
|
1.780E-1
|
2
|
30
|
|
26
|
GO:0034506
|
chromosome, centromeric core domain
|
|
1.836E-3
|
9.110E-3
|
4.957E-2
|
2.369E-1
|
1
|
1
|
|
27
|
GO:0044448
|
cell cortex part
|
|
2.051E-3
|
9.800E-3
|
5.332E-2
|
2.646E-1
|
3
|
138
|
|
28
|
GO:0005769
|
early endosome
|
|
2.529E-3
|
1.165E-2
|
6.340E-2
|
3.263E-1
|
4
|
314
|
|
29
|
GO:0031253
|
cell projection membrane
|
|
3.091E-3
|
1.375E-2
|
7.482E-2
|
3.988E-1
|
4
|
332
|
|
30
|
GO:0032154
|
cleavage furrow
|
|
3.649E-3
|
1.518E-2
|
8.262E-2
|
4.707E-1
|
2
|
49
|
|
31
|
GO:0097610
|
cell surface furrow
|
|
3.649E-3
|
1.518E-2
|
8.262E-2
|
4.707E-1
|
2
|
49
|
|
32
|
GO:0072686
|
mitotic spindle
|
|
6.149E-3
|
2.479E-2
|
1.349E-1
|
7.932E-1
|
2
|
64
|
|
33
|
GO:1990357
|
terminal web
|
|
9.148E-3
|
3.576E-2
|
1.946E-1
|
1.000E0
|
1
|
5
|
|
34
|
GO:0031105
|
septin complex
|
|
1.097E-2
|
4.043E-2
|
2.200E-1
|
1.000E0
|
1
|
6
|
|
35
|
GO:0030121
|
AP-1 adaptor complex
|
|
1.097E-2
|
4.043E-2
|
2.200E-1
|
1.000E0
|
1
|
6
|
Show 30 more annotations
|
4: Human Phenotype [Display Chart]
14 input genes in category / 738 annotations before applied cutoff / 4707 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
HP:0007590
|
Aplasia cutis congenita over posterior parietal area
|
|
1.711E-4
|
4.201E-2
|
3.017E-1
|
1.263E-1
|
2
|
7
|
|
2
|
HP:0004476
|
Aplasia cutis congenita over parietal area
|
|
1.711E-4
|
4.201E-2
|
3.017E-1
|
1.263E-1
|
2
|
7
|
|
3
|
HP:0007589
|
Aplasia cutis congenita on trunk or limbs
|
|
1.711E-4
|
4.201E-2
|
3.017E-1
|
1.263E-1
|
2
|
7
|
|
4
|
HP:0030011
|
Imperforate hymen
|
|
2.277E-4
|
4.201E-2
|
3.017E-1
|
1.681E-1
|
2
|
8
|
|
5: Mouse Phenotype [Display Chart]
27 input genes in category / 861 annotations before applied cutoff / 10355 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
MP:0008765
|
decreased mast cell degranulation
|
|
8.656E-6
|
7.453E-3
|
5.467E-2
|
7.453E-3
|
3
|
16
|
|
2
|
MP:0008763
|
abnormal mast cell degranulation
|
|
5.522E-5
|
2.377E-2
|
1.744E-1
|
4.754E-2
|
3
|
29
|
|
3
|
MP:0005095
|
decreased T cell proliferation
|
|
1.677E-4
|
4.813E-2
|
3.531E-1
|
1.444E-1
|
5
|
206
|
|
6: Domain [Display Chart]
35 input genes in category / 171 annotations before applied cutoff / 18735 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
PS51420
|
RHO
|
PROSITE
|
2.781E-26
|
4.756E-24
|
2.721E-23
|
4.756E-24
|
11
|
20
|
|
2
|
IPR026791
|
DOCK
|
InterPro
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
3
|
PF06920
|
DHR-2
|
Pfam
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
4
|
IPR027357
|
DHR-2
|
InterPro
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
5
|
IPR027007
|
DHR-1 domain
|
InterPro
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
6
|
PS51650
|
DHR 1
|
PROSITE
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
7
|
PF14429
|
DOCK-C2
|
Pfam
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
8
|
PS51651
|
DHR 2
|
PROSITE
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
9
|
IPR010703
|
DOCK C
|
InterPro
|
4.953E-24
|
9.410E-23
|
5.384E-22
|
8.469E-22
|
9
|
11
|
|
10
|
PF00071
|
Ras
|
Pfam
|
7.032E-16
|
1.202E-14
|
6.880E-14
|
1.202E-13
|
11
|
136
|
|
11
|
IPR001806
|
Small GTPase
|
InterPro
|
4.353E-15
|
6.767E-14
|
3.872E-13
|
7.444E-13
|
11
|
160
|
|
12
|
IPR005225
|
Small GTP-bd dom
|
InterPro
|
7.019E-15
|
1.000E-13
|
5.723E-13
|
1.200E-12
|
11
|
167
|
|
13
|
IPR021816
|
DOCK C/D N
|
InterPro
|
1.012E-13
|
1.236E-12
|
7.071E-12
|
1.730E-11
|
5
|
6
|
|
14
|
PF11878
|
DUF3398
|
Pfam
|
1.012E-13
|
1.236E-12
|
7.071E-12
|
1.730E-11
|
5
|
6
|
|
15
|
PF16172
|
DOCK N
|
Pfam
|
5.095E-11
|
5.445E-10
|
3.116E-9
|
8.712E-9
|
4
|
5
|
|
16
|
IPR032376
|
DOCK N
|
InterPro
|
5.095E-11
|
5.445E-10
|
3.116E-9
|
8.712E-9
|
4
|
5
|
|
17
|
PF00169
|
PH
|
Pfam
|
8.081E-9
|
8.128E-8
|
4.651E-7
|
1.382E-6
|
8
|
230
|
|
18
|
SM00233
|
PH
|
SMART
|
3.634E-8
|
3.284E-7
|
1.879E-6
|
6.215E-6
|
8
|
279
|
|
19
|
PS50003
|
PH DOMAIN
|
PROSITE
|
3.736E-8
|
3.284E-7
|
1.879E-6
|
6.389E-6
|
8
|
280
|
|
20
|
IPR001849
|
PH domain
|
InterPro
|
3.841E-8
|
3.284E-7
|
1.879E-6
|
6.568E-6
|
8
|
281
|
|
21
|
2.30.29.30
|
-
|
Gene3D
|
4.816E-7
|
3.921E-6
|
2.244E-5
|
8.235E-5
|
8
|
391
|
|
22
|
IPR001331
|
GDS CDC24 CS
|
InterPro
|
8.012E-7
|
6.228E-6
|
3.563E-5
|
1.370E-4
|
4
|
39
|
|
23
|
IPR011993
|
PH dom-like
|
InterPro
|
9.355E-7
|
6.955E-6
|
3.980E-5
|
1.600E-4
|
8
|
427
|
|
24
|
IPR016024
|
ARM-type fold
|
InterPro
|
2.647E-6
|
1.817E-5
|
1.040E-4
|
4.527E-4
|
7
|
340
|
|
25
|
SM00326
|
SH3
|
SMART
|
2.763E-6
|
1.817E-5
|
1.040E-4
|
4.724E-4
|
6
|
217
|
|
26
|
PS50002
|
SH3
|
PROSITE
|
2.763E-6
|
1.817E-5
|
1.040E-4
|
4.724E-4
|
6
|
217
|
|
27
|
IPR001452
|
SH3 domain
|
InterPro
|
3.070E-6
|
1.944E-5
|
1.113E-4
|
5.250E-4
|
6
|
221
|
|
28
|
PS00741
|
DH 1
|
PROSITE
|
5.621E-6
|
3.433E-5
|
1.964E-4
|
9.612E-4
|
4
|
63
|
|
29
|
SM00229
|
RasGEFN
|
SMART
|
6.662E-6
|
3.928E-5
|
2.248E-4
|
1.139E-3
|
3
|
20
|
|
30
|
SM00325
|
RhoGEF
|
SMART
|
7.634E-6
|
4.193E-5
|
2.399E-4
|
1.305E-3
|
4
|
68
|
|
31
|
PF00618
|
RasGEF N
|
Pfam
|
7.763E-6
|
4.193E-5
|
2.399E-4
|
1.327E-3
|
3
|
21
|
|
32
|
PS50010
|
DH 2
|
PROSITE
|
8.572E-6
|
4.193E-5
|
2.399E-4
|
1.466E-3
|
4
|
70
|
|
33
|
PF00621
|
RhoGEF
|
Pfam
|
8.572E-6
|
4.193E-5
|
2.399E-4
|
1.466E-3
|
4
|
70
|
|
34
|
IPR000651
|
Ras-like Gua-exchang fac N
|
InterPro
|
8.977E-6
|
4.193E-5
|
2.399E-4
|
1.535E-3
|
3
|
22
|
|
35
|
PS50212
|
RASGEF NTER
|
PROSITE
|
8.977E-6
|
4.193E-5
|
2.399E-4
|
1.535E-3
|
3
|
22
|
|
36
|
IPR000219
|
DH-domain
|
InterPro
|
9.072E-6
|
4.193E-5
|
2.399E-4
|
1.551E-3
|
4
|
71
|
|
37
|
1.20.900.10
|
-
|
Gene3D
|
9.072E-6
|
4.193E-5
|
2.399E-4
|
1.551E-3
|
4
|
71
|
|
38
|
PS00720
|
RASGEF
|
PROSITE
|
1.508E-5
|
6.785E-5
|
3.882E-4
|
2.578E-3
|
3
|
26
|
|
39
|
PF07653
|
SH3 2
|
Pfam
|
2.035E-5
|
8.698E-5
|
4.977E-4
|
3.479E-3
|
4
|
87
|
|
40
|
IPR011511
|
SH3 2
|
InterPro
|
2.035E-5
|
8.698E-5
|
4.977E-4
|
3.479E-3
|
4
|
87
|
|
41
|
PS50009
|
RASGEF CAT
|
PROSITE
|
2.111E-5
|
8.708E-5
|
4.982E-4
|
3.610E-3
|
3
|
29
|
|
42
|
SM00147
|
RasGEF
|
SMART
|
2.342E-5
|
8.708E-5
|
4.982E-4
|
4.006E-3
|
3
|
30
|
|
43
|
1.10.840.10
|
-
|
Gene3D
|
2.342E-5
|
8.708E-5
|
4.982E-4
|
4.006E-3
|
3
|
30
|
|
44
|
PF00617
|
RasGEF
|
Pfam
|
2.342E-5
|
8.708E-5
|
4.982E-4
|
4.006E-3
|
3
|
30
|
|
45
|
IPR023578
|
Ras GEF dom
|
InterPro
|
2.342E-5
|
8.708E-5
|
4.982E-4
|
4.006E-3
|
3
|
30
|
|
46
|
IPR001895
|
RASGEF cat dom
|
InterPro
|
2.342E-5
|
8.708E-5
|
4.982E-4
|
4.006E-3
|
3
|
30
|
|
47
|
IPR019804
|
Ras G-nucl-exch fac CS
|
InterPro
|
3.042E-4
|
1.107E-3
|
6.333E-3
|
5.202E-2
|
2
|
14
|
|
48
|
IPR031970
|
Anillin N
|
InterPro
|
1.868E-3
|
5.324E-3
|
3.046E-2
|
3.195E-1
|
1
|
1
|
|
49
|
IPR030235
|
PLS1
|
InterPro
|
1.868E-3
|
5.324E-3
|
3.046E-2
|
3.195E-1
|
1
|
1
|
|
50
|
IPR030717
|
DOCK1
|
InterPro
|
1.868E-3
|
5.324E-3
|
3.046E-2
|
3.195E-1
|
1
|
1
|
Show 45 more annotations
|
7: Pathway [Display Chart]
32 input genes in category / 449 annotations before applied cutoff / 12450 genes in category
|
8: Pubmed [Display Chart]
35 input genes in category / 5392 annotations before applied cutoff / 38193 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
12432077
|
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.
|
Pubmed
|
2.403E-32
|
1.295E-28
|
1.188E-27
|
1.295E-28
|
11
|
14
|
|
2
|
12879077
|
RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo.
|
Pubmed
|
7.890E-17
|
2.127E-13
|
1.950E-12
|
4.254E-13
|
6
|
10
|
|
3
|
21930703
|
The Arf family GTPase Arl4A complexes with ELMO proteins to promote actin cytoskeleton remodeling and reveals a versatile Ras-binding domain in the ELMO proteins family.
|
Pubmed
|
6.434E-16
|
1.156E-12
|
1.060E-11
|
3.469E-12
|
6
|
13
|
|
4
|
11368848
|
Interactions between Rho GTPases and Rho GDP dissociation inhibitor (Rho-GDI).
|
Pubmed
|
1.006E-14
|
1.356E-11
|
1.243E-10
|
5.422E-11
|
5
|
7
|
|
5
|
15761153
|
High-throughput mapping of a dynamic signaling network in mammalian cells.
|
Pubmed
|
2.431E-14
|
2.622E-11
|
2.404E-10
|
1.311E-10
|
10
|
256
|
|
6
|
12730235
|
Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells.
|
Pubmed
|
1.204E-13
|
1.082E-10
|
9.925E-10
|
6.494E-10
|
5
|
10
|
|
7
|
18056264
|
Specific recognition of Rac2 and Cdc42 by DOCK2 and DOCK9 guanine nucleotide exchange factors.
|
Pubmed
|
5.907E-13
|
4.550E-10
|
4.172E-9
|
3.185E-9
|
4
|
4
|
|
8
|
12842009
|
Rnd proteins function as RhoA antagonists by activating p190 RhoGAP.
|
Pubmed
|
2.951E-12
|
1.447E-9
|
1.327E-8
|
1.591E-8
|
4
|
5
|
|
9
|
10559471
|
Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins.
|
Pubmed
|
2.951E-12
|
1.447E-9
|
1.327E-8
|
1.591E-8
|
4
|
5
|
|
10
|
15023524
|
DEF6, a novel PH-DH-like domain protein, is an upstream activator of the Rho GTPases Rac1, Cdc42, and RhoA.
|
Pubmed
|
2.951E-12
|
1.447E-9
|
1.327E-8
|
1.591E-8
|
4
|
5
|
|
11
|
21454543
|
Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2).
|
Pubmed
|
2.951E-12
|
1.447E-9
|
1.327E-8
|
1.591E-8
|
4
|
5
|
|
12
|
15864311
|
Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1.
|
Pubmed
|
8.849E-12
|
3.976E-9
|
3.646E-8
|
4.771E-8
|
4
|
6
|
|
13
|
15075243
|
Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.
|
Pubmed
|
2.063E-11
|
7.947E-9
|
7.287E-8
|
1.113E-7
|
4
|
7
|
|
14
|
9490022
|
Differential properties of D4/LyGDI versus RhoGDI: phosphorylation and rho GTPase selectivity.
|
Pubmed
|
2.063E-11
|
7.947E-9
|
7.287E-8
|
1.113E-7
|
4
|
7
|
|
15
|
12944407
|
Concerted regulation of cell dynamics by BNIP-2 and Cdc42GAP homology/Sec14p-like, proline-rich, and GTPase-activating protein domains of a novel Rho GTPase-activating protein, BPGAP1.
|
Pubmed
|
4.124E-11
|
1.235E-8
|
1.133E-7
|
2.224E-7
|
4
|
8
|
|
16
|
24276241
|
cIAP1 regulates TNF-mediated cdc42 activation and filopodia formation.
|
Pubmed
|
4.124E-11
|
1.235E-8
|
1.133E-7
|
2.224E-7
|
4
|
8
|
|
17
|
16188938
|
p190 Rho-GTPase activating protein associates with plexins and it is required for semaphorin signalling.
|
Pubmed
|
4.124E-11
|
1.235E-8
|
1.133E-7
|
2.224E-7
|
4
|
8
|
|
18
|
22453919
|
GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.
|
Pubmed
|
4.124E-11
|
1.235E-8
|
1.133E-7
|
2.224E-7
|
4
|
8
|
|
19
|
9535855
|
Interaction of Rac1 with GTPase-activating proteins and putative effectors. A comparison with Cdc42 and RhoA.
|
Pubmed
|
7.418E-11
|
2.000E-8
|
1.834E-7
|
4.000E-7
|
4
|
9
|
|
20
|
15652748
|
Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis.
|
Pubmed
|
7.418E-11
|
2.000E-8
|
1.834E-7
|
4.000E-7
|
4
|
9
|
|
21
|
21423176
|
Analysis of the myosin-II-responsive focal adhesion proteome reveals a role for β-Pix in negative regulation of focal adhesion maturation.
|
Pubmed
|
1.722E-10
|
4.422E-8
|
4.055E-7
|
9.286E-7
|
8
|
285
|
|
22
|
25074804
|
Coronin-1C and RCC2 guide mesenchymal migration by trafficking Rac1 and controlling GEF exposure.
|
Pubmed
|
1.940E-10
|
4.756E-8
|
4.361E-7
|
1.046E-6
|
4
|
11
|
|
23
|
19126596
|
Essential role of Rac1 and Rac3 GTPases in neuronal development.
|
Pubmed
|
2.909E-10
|
6.535E-8
|
5.992E-7
|
1.568E-6
|
4
|
12
|
|
24
|
12819203
|
GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.
|
Pubmed
|
2.909E-10
|
6.535E-8
|
5.992E-7
|
1.568E-6
|
4
|
12
|
|
25
|
21029865
|
EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation.
|
Pubmed
|
4.199E-10
|
7.919E-8
|
7.261E-7
|
2.264E-6
|
4
|
13
|
|
26
|
11604131
|
Plexin signaling via off-track and rho family GTPases.
|
Pubmed
|
4.199E-10
|
7.919E-8
|
7.261E-7
|
2.264E-6
|
4
|
13
|
|
27
|
20936779
|
A human MAP kinase interactome.
|
Pubmed
|
4.278E-10
|
7.919E-8
|
7.261E-7
|
2.307E-6
|
9
|
486
|
|
28
|
22461493
|
Signaling and cytoskeletal requirements in erythroblast enucleation.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
29
|
16311049
|
Differences in the gestational pattern of mRNA expression of the Rnd family in rat and human myometria.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
30
|
9786927
|
CdGAP, a novel proline-rich GTPase-activating protein for Cdc42 and Rac.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
31
|
10220378
|
G protein beta gamma subunit-dependent Rac-guanine nucleotide exchange activity of Ras-GRF1/CDC25(Mm).
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
32
|
2674130
|
rac, a novel ras-related family of proteins that are botulinum toxin substrates.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
33
|
25365944
|
Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
34
|
16982419
|
The Rac activator DOCK7 regulates neuronal polarity through local phosphorylation of stathmin/Op18.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
35
|
22123845
|
Rac signaling in osteoblastic cells is required for normal bone development but is dispensable for hematopoietic development.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
36
|
17517067
|
Rac1, RhoA, and Cdc42 participate in HeLa cell invasion by group B streptococcus.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
37
|
16081809
|
Isoform-specific membrane targeting mechanism of Rac during Fc gamma R-mediated phagocytosis: positive charge-dependent and independent targeting mechanism of Rac to the phagosome.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
38
|
12538863
|
Biochemical characterization of the Yersinia YopT protease: cleavage site and recognition elements in Rho GTPases.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
39
|
20945370
|
Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
40
|
18334926
|
[The Rho protein family and its role in the cellular cytoskeleton].
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
41
|
17027967
|
Dock4 is regulated by RhoG and promotes Rac-dependent cell migration.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
42
|
16492808
|
Targeting and activation of Rac1 are mediated by the exchange factor beta-Pix.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
43
|
9531558
|
A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
44
|
19596003
|
Adiponectin promotes migration activities of endothelial progenitor cells via Cdc42/Rac1.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
45
|
24859002
|
A Trio-Rac1-Pak1 signalling axis drives invadopodia disassembly.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
46
|
11822867
|
Involvement of Rho GTPases and their effectors in the secretory process of PC12 cells.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
47
|
12115629
|
Extension, retraction and contraction in the formation of a dendritic cell dendrite: distinct roles for Rho GTPases.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
48
|
15901767
|
RhoGTPase activation is a key step in renal epithelial mesenchymal transdifferentiation.
|
Pubmed
|
7.049E-10
|
7.919E-8
|
7.261E-7
|
3.801E-6
|
3
|
3
|
|
49
|
15649357
|
The Cool-2/alpha-Pix protein mediates a Cdc42-Rac signaling cascade.
|
Pubmed
|
2.818E-9
|
1.853E-7
|
1.699E-6
|
1.519E-5
|
3
|
4
|
|
50
|
17702745
|
Regulation of ephexin1, a guanine nucleotide exchange factor of Rho family GTPases, by fibroblast growth factor receptor-mediated tyrosine phosphorylation.
|
Pubmed
|
2.818E-9
|
1.853E-7
|
1.699E-6
|
1.519E-5
|
3
|
4
|
Show 45 more annotations
|
9: Interaction [Display Chart]
34 input genes in category / 1195 annotations before applied cutoff / 17703 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
int:RAC1
|
RAC1 interactions
|
|
2.012E-14
|
2.404E-11
|
1.842E-10
|
2.404E-11
|
12
|
250
|
|
2
|
int:ARHGDIB
|
ARHGDIB interactions
|
|
1.674E-12
|
6.668E-10
|
5.110E-9
|
2.001E-9
|
6
|
21
|
|
3
|
int:ARHGAP35
|
ARHGAP35 interactions
|
|
1.674E-12
|
6.668E-10
|
5.110E-9
|
2.001E-9
|
6
|
21
|
|
4
|
int:CDC42
|
CDC42 interactions
|
|
1.334E-11
|
3.986E-9
|
3.055E-8
|
1.594E-8
|
10
|
234
|
|
5
|
int:ARHGDIG
|
ARHGDIG interactions
|
|
2.446E-11
|
5.427E-9
|
4.159E-8
|
2.923E-8
|
5
|
13
|
|
6
|
int:ARHGDIA
|
ARHGDIA interactions
|
|
2.725E-11
|
5.427E-9
|
4.159E-8
|
3.256E-8
|
8
|
110
|
|
7
|
int:RAC2
|
RAC2 interactions
|
|
5.888E-11
|
1.005E-8
|
7.703E-8
|
7.036E-8
|
6
|
36
|
|
8
|
int:PLXNB1
|
PLXNB1 interactions
|
|
1.505E-9
|
1.999E-7
|
1.532E-6
|
1.799E-6
|
5
|
27
|
|
9
|
int:ELMO1
|
ELMO1 interactions
|
|
1.505E-9
|
1.999E-7
|
1.532E-6
|
1.799E-6
|
5
|
27
|
|
10
|
int:MCF2L
|
MCF2L interactions
|
|
5.551E-9
|
6.633E-7
|
5.083E-6
|
6.633E-6
|
4
|
12
|
|
11
|
int:DEF6
|
DEF6 interactions
|
|
6.943E-9
|
7.543E-7
|
5.781E-6
|
8.297E-6
|
5
|
36
|
|
12
|
int:DOCK8
|
DOCK8 interactions
|
|
2.223E-8
|
2.213E-6
|
1.696E-5
|
2.656E-5
|
5
|
45
|
|
13
|
int:ARHGAP5
|
ARHGAP5 interactions
|
|
6.630E-8
|
5.871E-6
|
4.500E-5
|
7.923E-5
|
4
|
21
|
|
14
|
int:PAK2
|
PAK2 interactions
|
|
6.879E-8
|
5.871E-6
|
4.500E-5
|
8.220E-5
|
6
|
113
|
|
15
|
int:TGFBR1
|
TGFBR1 interactions
|
|
8.489E-8
|
6.763E-6
|
5.183E-5
|
1.014E-4
|
7
|
199
|
|
16
|
int:PLEKHG5
|
PLEKHG5 interactions
|
|
2.247E-7
|
1.496E-5
|
1.147E-4
|
2.685E-4
|
4
|
28
|
|
17
|
int:OPHN1
|
OPHN1 interactions
|
|
2.254E-7
|
1.496E-5
|
1.147E-4
|
2.693E-4
|
3
|
7
|
|
18
|
int:ARHGAP31
|
ARHGAP31 interactions
|
|
2.254E-7
|
1.496E-5
|
1.147E-4
|
2.693E-4
|
3
|
7
|
|
19
|
int:DOCK1
|
DOCK1 interactions
|
|
2.999E-7
|
1.886E-5
|
1.445E-4
|
3.584E-4
|
4
|
30
|
|
20
|
int:RAP1GDS1
|
RAP1GDS1 interactions
|
|
5.325E-7
|
3.070E-5
|
2.352E-4
|
6.363E-4
|
5
|
84
|
|
21
|
int:ARHGEF25
|
ARHGEF25 interactions
|
|
5.394E-7
|
3.070E-5
|
2.352E-4
|
6.446E-4
|
3
|
9
|
|
22
|
int:FRS2
|
FRS2 interactions
|
|
7.159E-7
|
3.889E-5
|
2.980E-4
|
8.555E-4
|
4
|
37
|
|
23
|
int:DOCK7
|
DOCK7 interactions
|
|
8.390E-7
|
4.359E-5
|
3.341E-4
|
1.003E-3
|
5
|
92
|
|
24
|
int:MCF2
|
MCF2 interactions
|
|
1.057E-6
|
5.052E-5
|
3.871E-4
|
1.263E-3
|
3
|
11
|
|
25
|
int:PLEKHG2
|
PLEKHG2 interactions
|
|
1.057E-6
|
5.052E-5
|
3.871E-4
|
1.263E-3
|
3
|
11
|
|
26
|
int:TRIO
|
TRIO interactions
|
|
1.205E-6
|
5.334E-5
|
4.087E-4
|
1.440E-3
|
4
|
42
|
|
27
|
int:ARHGEF6
|
ARHGEF6 interactions
|
|
1.205E-6
|
5.334E-5
|
4.087E-4
|
1.440E-3
|
4
|
42
|
|
28
|
int:BCR
|
BCR interactions
|
|
1.270E-6
|
5.422E-5
|
4.155E-4
|
1.518E-3
|
5
|
100
|
|
29
|
int:PLD1
|
PLD1 interactions
|
|
1.907E-6
|
7.860E-5
|
6.023E-4
|
2.279E-3
|
4
|
47
|
|
30
|
int:MYO6
|
MYO6 interactions
|
|
2.052E-6
|
8.172E-5
|
6.263E-4
|
2.452E-3
|
6
|
201
|
|
31
|
int:VAV1
|
VAV1 interactions
|
|
2.227E-6
|
8.585E-5
|
6.579E-4
|
2.661E-3
|
5
|
112
|
|
32
|
int:ARHGAP8
|
ARHGAP8 interactions
|
|
2.899E-6
|
1.083E-4
|
8.296E-4
|
3.464E-3
|
3
|
15
|
|
33
|
int:NCK1
|
NCK1 interactions
|
|
3.260E-6
|
1.180E-4
|
9.046E-4
|
3.895E-3
|
5
|
121
|
|
34
|
int:PAK1
|
PAK1 interactions
|
|
3.533E-6
|
1.217E-4
|
9.323E-4
|
4.222E-3
|
5
|
123
|
|
35
|
int:ELMO3
|
ELMO3 interactions
|
|
3.563E-6
|
1.217E-4
|
9.323E-4
|
4.258E-3
|
3
|
16
|
|
36
|
int:ARHGEF7
|
ARHGEF7 interactions
|
|
3.880E-6
|
1.253E-4
|
9.604E-4
|
4.637E-3
|
4
|
56
|
|
37
|
int:CIT
|
CIT interactions
|
|
3.880E-6
|
1.253E-4
|
9.604E-4
|
4.637E-3
|
4
|
56
|
|
38
|
int:ARHGAP32
|
ARHGAP32 interactions
|
|
4.470E-6
|
1.406E-4
|
1.077E-3
|
5.341E-3
|
4
|
58
|
|
39
|
int:RCC2
|
RCC2 interactions
|
|
4.788E-6
|
1.467E-4
|
1.124E-3
|
5.722E-3
|
4
|
59
|
|
40
|
int:RAC3
|
RAC3 interactions
|
|
5.179E-6
|
1.547E-4
|
1.186E-3
|
6.188E-3
|
3
|
18
|
|
41
|
int:ELMO2
|
ELMO2 interactions
|
|
6.141E-6
|
1.732E-4
|
1.328E-3
|
7.339E-3
|
3
|
19
|
|
42
|
int:CRLF3
|
CRLF3 interactions
|
|
6.141E-6
|
1.732E-4
|
1.328E-3
|
7.339E-3
|
3
|
19
|
|
43
|
int:KTN1
|
KTN1 interactions
|
|
6.233E-6
|
1.732E-4
|
1.328E-3
|
7.449E-3
|
4
|
63
|
|
44
|
int:RGS14
|
RGS14 interactions
|
|
7.216E-6
|
1.916E-4
|
1.468E-3
|
8.623E-3
|
3
|
20
|
|
45
|
int:PAK3
|
PAK3 interactions
|
|
7.216E-6
|
1.916E-4
|
1.468E-3
|
8.623E-3
|
3
|
20
|
|
46
|
int:DOCK6
|
DOCK6 interactions
|
|
8.407E-6
|
2.138E-4
|
1.638E-3
|
1.005E-2
|
3
|
21
|
|
47
|
int:ICMT
|
ICMT interactions
|
|
8.407E-6
|
2.138E-4
|
1.638E-3
|
1.005E-2
|
3
|
21
|
|
48
|
int:RASGRF1
|
RASGRF1 interactions
|
|
1.117E-5
|
2.780E-4
|
2.130E-3
|
1.334E-2
|
3
|
23
|
|
49
|
int:VAV3
|
VAV3 interactions
|
|
1.274E-5
|
3.108E-4
|
2.382E-3
|
1.523E-2
|
3
|
24
|
|
50
|
int:AGAP1
|
AGAP1 interactions
|
|
1.539E-5
|
3.677E-4
|
2.818E-3
|
1.839E-2
|
4
|
79
|
Show 45 more annotations
|
10: Cytoband [Display Chart]
35 input genes in category / 34 annotations before applied cutoff / 34661 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
2q23.3
|
2q23.3
|
|
1.861E-4
|
6.326E-3
|
2.605E-2
|
6.326E-3
|
2
|
20
|
|
2
|
10q26.13-q26.3
|
10q26.13-q26.3
|
|
1.010E-3
|
1.717E-2
|
7.069E-2
|
3.433E-2
|
1
|
1
|
|
3
|
11q13-q14
|
11q13-q14
|
|
2.019E-3
|
2.288E-2
|
9.421E-2
|
6.863E-2
|
1
|
2
|
|
4
|
7p15-p14
|
7p15-p14
|
|
4.033E-3
|
2.743E-2
|
1.129E-1
|
1.371E-1
|
1
|
4
|
|
5
|
11p15.5-p15.4
|
11p15.5-p15.4
|
|
4.033E-3
|
2.743E-2
|
1.129E-1
|
1.371E-1
|
1
|
4
|
|
11: Transcription Factor Binding Site [Display Chart]
26 input genes in category / 239 annotations before applied cutoff / 9770 genes in category
|
12: Gene Family [Display Chart]
23 input genes in category / 8 annotations before applied cutoff / 18194 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
390
|
Rho family GTPases
|
genenames.org
|
1.251E-28
|
1.000E-27
|
2.719E-27
|
1.000E-27
|
11
|
20
|
|
2
|
682
|
Zinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors
|
genenames.org
|
4.529E-9
|
1.811E-8
|
4.923E-8
|
3.623E-8
|
7
|
206
|
|
3
|
722
|
Rho guanine nucleotide exchange factors
|
genenames.org
|
1.328E-6
|
3.540E-6
|
9.622E-6
|
1.062E-5
|
4
|
66
|
|
4
|
542
|
Endogenous ligands
|
genenames.org
|
3.188E-3
|
6.376E-3
|
1.733E-2
|
2.550E-2
|
3
|
237
|
|
5
|
732
|
Septins
|
genenames.org
|
1.632E-2
|
2.610E-2
|
7.095E-2
|
1.305E-1
|
1
|
13
|
|
6
|
863
|
EF-hand domain containing
|
genenames.org
|
3.091E-2
|
4.121E-2
|
1.120E-1
|
2.473E-1
|
2
|
219
|
Show 1 more annotation
|
13: Coexpression [Display Chart]
35 input genes in category / 3238 annotations before applied cutoff / 23137 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
M5893
|
Genes important for mitotic spindle assembly.
|
MSigDB H: Hallmark Gene Sets (v6.0)
|
1.778E-8
|
2.879E-5
|
2.493E-4
|
5.758E-5
|
7
|
200
|
|
2
|
M7515
|
Genes up-regulated in CD4 [GeneID=920] T cells: non-Tfh versus Tfh (T follicular helper).
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.778E-8
|
2.879E-5
|
2.493E-4
|
5.758E-5
|
7
|
200
|
|
3
|
17312329-SuppTable4
|
Human Leukemia Juric07 106genes
|
GeneSigDB
|
4.918E-8
|
5.308E-5
|
4.597E-4
|
1.592E-4
|
5
|
66
|
|
4
|
15548366-Table2
|
Mouse Bladder Yao04 53genes
|
GeneSigDB
|
8.141E-7
|
6.590E-4
|
5.707E-3
|
2.636E-3
|
4
|
48
|
|
5
|
14583454-TableS1
|
Human Brain Godard03 239genes
|
GeneSigDB
|
1.041E-6
|
6.742E-4
|
5.839E-3
|
3.371E-3
|
6
|
226
|
|
6
|
20460173-ImmPortNaturalKillerCellCytotoxicity
|
Human Immune Kong10 135genes ImmPort NaturalKillerCellCytotoxicity
|
GeneSigDB
|
1.259E-6
|
6.797E-4
|
5.886E-3
|
4.078E-3
|
5
|
126
|
|
7
|
M4737
|
ECM related genes up-regulated early (within 30 min) in dermal fibroblasts after addition of TGFB1 [GeneID=7040].
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.756E-6
|
8.124E-4
|
7.035E-3
|
5.687E-3
|
4
|
58
|
|
8
|
M3955
|
Integrin, VEGF, Wnt and TGFbeta signaling pathway genes up-regulated in PC-3 cells (prostate cancer) after knockdown of PDEF [GeneID=25803] by RNAi.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.966E-6
|
1.605E-3
|
1.390E-2
|
1.284E-2
|
4
|
71
|
|
9
|
M2200
|
Genes enriched at every T lymphocyte differentiation stage compared to the early passage fetal thymic stromal cultures (TSC).
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.207E-5
|
4.342E-3
|
3.761E-2
|
3.908E-2
|
5
|
200
|
|
10
|
M453
|
Genes up-regulated in primary keratinocytes at 6 h after UVB irradiation.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.378E-5
|
7.702E-3
|
6.670E-2
|
7.702E-2
|
3
|
37
|
|
11
|
M16643
|
ECM related genes up-regulated later than 30 min following addition of TGFB1 [GeneID=7040] in dermal fibroblasts.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.792E-5
|
8.218E-3
|
7.117E-2
|
9.040E-2
|
3
|
39
|
|
12
|
M8779
|
Proteins showing significant overexpression in lung cancer cell lines relative to normal bronchial epithelial cell lines.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.250E-5
|
8.769E-3
|
7.594E-2
|
1.052E-1
|
3
|
41
|
|
13
|
17409455-TableS3
|
Human Breast Winter07 67genes
|
GeneSigDB
|
5.570E-5
|
1.387E-2
|
1.201E-1
|
1.804E-1
|
3
|
49
|
|
14
|
M2683
|
Genes down-regulated in head and neck tumor samples which clustered around known hypoxia genes.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
6.661E-5
|
1.541E-2
|
1.334E-1
|
2.157E-1
|
3
|
52
|
|
15
|
19286929-SuppTable2a
|
Mouse Lung Rangasamy09 168genes
|
GeneSigDB
|
8.416E-5
|
1.804E-2
|
1.562E-1
|
2.725E-1
|
4
|
154
|
|
16
|
20436685-ST4-2
|
Human Breast Pothuri10 526genes
|
GeneSigDB
|
8.914E-5
|
1.804E-2
|
1.562E-1
|
2.886E-1
|
6
|
495
|
|
17
|
M2646
|
Matrix, adhesion or cytoskeleton genes induced by NF-kappaB in primary keratinocytes and fibroblasts.
|
MSigDB C6: Oncogenic Signatures (v6.0)
|
9.928E-5
|
1.891E-2
|
1.638E-1
|
3.215E-1
|
2
|
10
|
|
18
|
M9090
|
Genes up-regulated in CD4 T conv: control versus over-expression of LEF1 [GeneID=51176].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.205E-4
|
2.068E-2
|
1.791E-1
|
3.903E-1
|
4
|
169
|
|
19
|
M9154
|
Genes up-regulated in CD4 T conv over-expressing: IRF4 [GeneID=3662] versus IRF4 and FOXP3 [GeneID=3662;50943].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.319E-4
|
2.068E-2
|
1.791E-1
|
4.271E-1
|
4
|
173
|
|
20
|
M6684
|
Genes up-regulated in ndothelial cells: untreated versus interferon alpha.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
1.349E-4
|
2.068E-2
|
1.791E-1
|
4.367E-1
|
4
|
174
|
|
21
|
15545975-Table1
|
Human Colon Arango04 254genes
|
GeneSigDB
|
1.440E-4
|
2.068E-2
|
1.791E-1
|
4.663E-1
|
4
|
177
|
|
22
|
M566
|
Cluster 4: ECM related genes up-regulated in dermal fibroblasts later than 30 min after TGFB1 [GeneID=7040] addition; kept increasing with time.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
1.716E-4
|
2.068E-2
|
1.791E-1
|
5.556E-1
|
2
|
13
|
|
23
|
M5321
|
Cluster 3: ECM related genes up-regulated in dermal fibroblasts within 30 min after TGFB1 [GeneID=7040] addition; returned rapidly to basal level after that.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.000E-4
|
2.068E-2
|
1.791E-1
|
6.476E-1
|
2
|
14
|
|
24
|
M4146
|
Genes up-regulated in comparison of dendritic cells (DC) stimulated with Gardiquimod (TLR7 agonist) at 4 h versus those stimulated with Gardiquimod (TLR7 agonist) at 24 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.256E-4
|
2.068E-2
|
1.791E-1
|
7.305E-1
|
4
|
199
|
|
25
|
M9356
|
Genes down-regulated in heterozygous knockout of BCL6 [GeneID=604]: follicular versus marginal zone source.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
26
|
M3945
|
Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 8 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 8 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
27
|
M3307
|
Genes up-regulated in comparison of unstimulated peripheral blood mononuclear cells (PBMC) 7 days after stimulation with YF17D vaccine versus PBMC 21 days after the stimulation.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
28
|
M3915
|
Genes up-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 4 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 4 h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
29
|
M7501
|
Genes up-regulated in CD4 [GeneID=920] follicular helper T cells (Tfh) with SH2D1A [GeneID=4068] knockout versus wildtype Tfh cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
30
|
M4938
|
Genes down-regulated in comparison of B cells versus monocytes.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
31
|
M8031
|
Genes down-regulated in bone marrow-derived macrophages: wildtype versus STAT6 [GeneID=6778] knockout.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
32
|
M6186
|
Genes up-regulated in NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with no peptide 0h versus NOD CD4 CD8 double positive thymocyte transgenic for the BDC2.5 TCR incubated with mimetope negative sel 16h.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
33
|
M5921
|
Genes encoding components of the complement system, which is part of the innate immune system.
|
MSigDB H: Hallmark Gene Sets (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
34
|
M3087
|
Genes up-regulated in comparison of systemic lupus erythematosus CD4 [GeneID=920] T cells versus systemic lupus erythematosus myeloid cells.
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
35
|
M7175
|
Genes up-regulated in B lymphocytes from cord blood: naïve versus transitional CR2 [GeneID=1380].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
36
|
M5277
|
Genes down-regulated in comparison of type 2 myeloid (T2M) cells treated with IL25 [GeneID=64806] versus neutrophils treated with IL25 [GeneID=64806].
|
MSigDB C7: Immunologic Signatures (v6.0)
|
2.300E-4
|
2.068E-2
|
1.791E-1
|
7.447E-1
|
4
|
200
|
|
37
|
M2509
|
Major ELAVL4 [GeneID=1996] associated mRNAs encoding proteins with functions in neuronal physiology.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
2.632E-4
|
2.304E-2
|
1.995E-1
|
8.524E-1
|
2
|
16
|
|
38
|
16341039-TableS7
|
Human Leukemia Bogni06 238genes
|
GeneSigDB
|
2.770E-4
|
2.360E-2
|
2.044E-1
|
8.968E-1
|
4
|
210
|
|
39
|
18381418-Table1
|
Mouse Prostate Ouyang08 121genes
|
GeneSigDB
|
2.877E-4
|
2.388E-2
|
2.068E-1
|
9.315E-1
|
3
|
85
|
|
40
|
M19695
|
Genes up-regulated in kidney biopsies from patients with acute transplant rejection compared to the biopsies from patients with well functioning kidneys more than 1-year post transplant.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.081E-4
|
2.494E-2
|
2.160E-1
|
9.976E-1
|
3
|
87
|
|
41
|
M16169
|
Genes able to induce cell death in an expression cDNA library screen.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.186E-4
|
2.516E-2
|
2.179E-1
|
1.000E0
|
3
|
88
|
|
42
|
17699775-SuppTable2
|
Human Lung Johnson07 571genes
|
GeneSigDB
|
3.454E-4
|
2.600E-2
|
2.251E-1
|
1.000E0
|
5
|
407
|
|
43
|
M11951
|
Genes up-regulated in primary keratinocytes by expression of p50 (NFKB1) and p65 (RELA) [GeneID=4790;5970] components of NFKB.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.517E-4
|
2.600E-2
|
2.251E-1
|
1.000E0
|
3
|
91
|
|
44
|
M12676
|
Class NT (non-tolerizeable) genes: induced during the first LPS stimulation and induced at equal or greater degree in tolerant macrophages.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
3.533E-4
|
2.600E-2
|
2.251E-1
|
1.000E0
|
5
|
409
|
|
45
|
15355895-Table2b
|
Human Bone Dring04 19genes
|
GeneSigDB
|
3.740E-4
|
2.691E-2
|
2.331E-1
|
1.000E0
|
2
|
19
|
|
46
|
16618722-Table1
|
Human InVitro Glesne06 108genes
|
GeneSigDB
|
4.503E-4
|
3.093E-2
|
2.678E-1
|
1.000E0
|
3
|
99
|
|
47
|
17161497-Table3
|
Human Lung Dracheva07 24genes
|
GeneSigDB
|
4.585E-4
|
3.093E-2
|
2.678E-1
|
1.000E0
|
2
|
21
|
|
48
|
M17772
|
Genes up-regulated in SW480 cells (colon cancer with mutated p53 [GeneID=7157]) upon expression of BRCA1 [GeneID=672] off an adenovirus vector.
|
MSigDB C2: CGP Curated Gene Sets (v6.0)
|
4.585E-4
|
3.093E-2
|
2.678E-1
|
1.000E0
|
2
|
21
|
|
49
|
19605494-TableS3
|
Mouse Skin Driskell09 685genes
|
GeneSigDB
|
4.780E-4
|
3.158E-2
|
2.735E-1
|
1.000E0
|
5
|
437
|
|
50
|
15459216-TableA2f
|
Human Leukemia Haslinger04 126genes
|
GeneSigDB
|
6.456E-4
|
4.181E-2
|
3.620E-1
|
1.000E0
|
3
|
112
|
Show 45 more annotations
|
14: Coexpression Atlas [Display Chart]
35 input genes in category / 2748 annotations before applied cutoff / 21829 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
GSM538245 500
|
Myeloid Cells, DC.4+.SLN, CD11b-FITC CD4-PE CD11c-Alexa750 CD8a-PacificBlue, Lymph Node, avg-3
|
Immgen.org, GSE15907
|
2.065E-7
|
5.675E-4
|
4.822E-3
|
5.675E-4
|
8
|
407
|
|
2
|
DevelopingKidney e15.5 Endothelial cells emap-29977 k3 500
|
DevelopingKidney e15.5 Endothelial cells emap-29977 k-means-cluster#3 top-relative-expression-ranked 500
|
Gudmap Mouse MOE430.2
|
8.477E-6
|
5.590E-3
|
4.749E-2
|
2.329E-2
|
3
|
25
|
|
3
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr GlobusPallidus Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr GlobusPallidus Top 200 Genes
|
BrainMap
|
1.236E-5
|
5.590E-3
|
4.749E-2
|
3.396E-2
|
6
|
328
|
|
4
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Pdgfa Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr.Pdgfa Top 200 Genes
|
BrainMap
|
2.059E-5
|
5.590E-3
|
4.749E-2
|
5.657E-2
|
6
|
359
|
|
5
|
GSM605837 500
|
Myeloid Cells, DC.8-4-11b-.Sp, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Spleen, avg-2
|
Immgen.org, GSE15907
|
2.630E-5
|
5.590E-3
|
4.749E-2
|
7.228E-2
|
6
|
375
|
|
6
|
GSM777041 500
|
Stromal Cells, Ep.MEChi.Th, CD45- EpCAm+ Ly51- MHCIIhi, Thymus, avg-2
|
Immgen.org, GSE15907
|
3.004E-5
|
5.590E-3
|
4.749E-2
|
8.256E-2
|
6
|
384
|
|
7
|
GSM605820 500
|
Myeloid Cells, DC.103+11b-.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3
|
Immgen.org, GSE15907
|
3.004E-5
|
5.590E-3
|
4.749E-2
|
8.256E-2
|
6
|
384
|
|
8
|
GSM854315 500
|
Myeloid Cells, MF.169+11chi.SLN, CD11b+ CD169+ CD11chigh, Lymph Node, avg-2
|
Immgen.org, GSE15907
|
3.048E-5
|
5.590E-3
|
4.749E-2
|
8.377E-2
|
6
|
385
|
|
9
|
GSM538265 500
|
Myeloid Cells, DC.8-4-11b+.Sp, CD11b CD4 CD45 CD11c CD8a, Spleen, avg-1
|
Immgen.org, GSE15907
|
3.518E-5
|
5.590E-3
|
4.749E-2
|
9.669E-2
|
6
|
395
|
|
10
|
GSM854241 500
|
Myeloid Cells, DC.103+11b-.Lu, MHCII+ CD11c+ CD103+ CD11b, Lung, avg-2
|
Immgen.org, GSE15907
|
3.881E-5
|
5.590E-3
|
4.749E-2
|
1.066E-1
|
6
|
402
|
|
11
|
GSM854269 500
|
Myeloid Cells, DC.103-11b+24+.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24+, Lung, avg-2
|
Immgen.org, GSE15907
|
3.990E-5
|
5.590E-3
|
4.749E-2
|
1.096E-1
|
6
|
404
|
|
12
|
GSM854273 500
|
Myeloid Cells, DC.103-11b+F4/80lo.Kd, CD45+ CD11c+ I-A/I-E+ CD11b+ F4/80lo, Kidney, avg-3
|
Immgen.org, GSE15907
|
4.101E-5
|
5.590E-3
|
4.749E-2
|
1.127E-1
|
6
|
406
|
|
13
|
GSM854287 500
|
Myeloid Cells, DC.8-4-11b+.SLN, CD11b-FITC CD4-PE CD11c-eFluor780 CD8a-eFluor450 C, Lymph Node, avg-1
|
Immgen.org, GSE15907
|
4.158E-5
|
5.590E-3
|
4.749E-2
|
1.143E-1
|
6
|
407
|
|
14
|
GSM605823 500
|
Myeloid Cells, DC.103-11b+.PolyIC.Lu, CD45 MHCII CD11c CD103 CD11b, Lung, avg-3
|
Immgen.org, GSE15907
|
4.273E-5
|
5.590E-3
|
4.749E-2
|
1.174E-1
|
6
|
409
|
|
15
|
GSM791122 500
|
Fetal Liver, SC.STSL.FL, IgM- CD24- CD117+ IL7R- CD150- CD48- AA4.1+ CD43+, Fetal Liver, avg-2
|
Immgen.org, GSE15907
|
4.331E-5
|
5.590E-3
|
4.749E-2
|
1.190E-1
|
6
|
410
|
|
16
|
GSM538239 500
|
Myeloid Cells, DC.103-11b+.Lv, CD45+ CD11c+ MHC-II + CD11b high CD103-, Liver, avg-3
|
Immgen.org, GSE15907
|
4.390E-5
|
5.590E-3
|
4.749E-2
|
1.206E-1
|
6
|
411
|
|
17
|
GSM538271 500
|
Myeloid Cells, DC.IIhilang+103-11b+.SLN, MHCIIhi CD11c+ Langerin+ CD103- CD11b+, Lymph Node, avg-3
|
Immgen.org, GSE15907
|
4.450E-5
|
5.590E-3
|
4.749E-2
|
1.223E-1
|
6
|
412
|
|
18
|
GSM605831 500
|
Myeloid Cells, DC.8-.Th, CD11b-FITC CD4-PE MHCII-APC CD11c-eFluor780 CD8-eF, Thymus, avg-3
|
Immgen.org, GSE15907
|
4.511E-5
|
5.590E-3
|
4.749E-2
|
1.240E-1
|
6
|
413
|
|
19
|
GSM605878 500
|
Myeloid Cells, Mo.6C-II+.Bl, CD115+ B220- CD43+ Ly6C- MHCIIhi, Blood, avg-2
|
Immgen.org, GSE15907
|
4.511E-5
|
5.590E-3
|
4.749E-2
|
1.240E-1
|
6
|
413
|
|
20
|
GSM854271 500
|
Myeloid Cells, DC.103-11b+24-.Lu, MHCII+ CD11c+ CD103- CD11b+ CD24-, Lung, avg-2
|
Immgen.org, GSE15907
|
4.572E-5
|
5.590E-3
|
4.749E-2
|
1.256E-1
|
6
|
414
|
|
21
|
gudmap dev gonad e13.5 F gudmap devVascOvary Flk 500
|
dev gonad e13.5 F DevVascOvary Flk top-relative-expression-ranked 500
|
Gudmap Mouse ST 1.0
|
4.696E-5
|
5.590E-3
|
4.749E-2
|
1.290E-1
|
6
|
416
|
|
22
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour Wilms R U/Kidney Tumour Wilms R4
|
Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Tumour Wilms R U/Kidney Tumour Wilms R4
|
Adult, Development, and Cancer types
|
4.780E-5
|
5.590E-3
|
4.749E-2
|
1.314E-1
|
3
|
44
|
|
23
|
GSM399442 500
|
Stem Cells, SC.LTSL.BM, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Bone marrow, avg-2
|
Immgen.org, GSE15907
|
5.085E-5
|
5.590E-3
|
4.749E-2
|
1.397E-1
|
6
|
422
|
|
24
|
GSM791126 500
|
Fetal Liver, SC.LTSL.FL, IgM- CD24- CD117+ IL7R- CD150+ CD48- AA4.1+ CD43+, Fetal Liver, avg-3
|
Immgen.org, GSE15907
|
5.152E-5
|
5.590E-3
|
4.749E-2
|
1.416E-1
|
6
|
423
|
|
25
|
GSM538231 500
|
Myeloid Cells, DC.103+11b-.Lu, CD11chi CD11b low CD103+ MHCII+ SiglecF-, Lung, avg-3
|
Immgen.org, GSE15907
|
5.220E-5
|
5.590E-3
|
4.749E-2
|
1.434E-1
|
6
|
424
|
|
26
|
GSM538282 500
|
Myeloid Cells, MF.Lu, CD11chi CD11b- CD103- MHCII- SiglecF+, Lung, avg-3
|
Immgen.org, GSE15907
|
5.289E-5
|
5.590E-3
|
4.749E-2
|
1.453E-1
|
6
|
425
|
|
27
|
GSM777059 500
|
Stromal Cells, LEC.MLN, gp38+ CD31+, Lymph Node, avg-4
|
Immgen.org, GSE15907
|
6.329E-5
|
6.441E-3
|
5.473E-2
|
1.739E-1
|
6
|
439
|
|
28
|
gudmap dev gonad e11.5 F ReproVasc Flk k3 1000
|
dev gonad e11.5 F ReproVasc Flk k-means-cluster#3 top-relative-expression-ranked 1000
|
Gudmap Mouse ST 1.0
|
6.738E-5
|
6.591E-3
|
5.600E-2
|
1.851E-1
|
6
|
444
|
|
29
|
GSM777063 500
|
Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4
|
Immgen.org, GSE15907
|
7.256E-5
|
6.591E-3
|
5.600E-2
|
1.994E-1
|
6
|
450
|
|
30
|
Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Top 200
|
Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Top 200
|
|
7.436E-5
|
6.591E-3
|
5.600E-2
|
2.043E-1
|
6
|
452
|
|
31
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Top 200
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Top 200
|
BrainMap
|
7.436E-5
|
6.591E-3
|
5.600E-2
|
2.043E-1
|
6
|
452
|
|
32
|
GSM777032 500
|
Stromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5
|
Immgen.org, GSE15907
|
7.806E-5
|
6.703E-3
|
5.695E-2
|
2.145E-1
|
6
|
456
|
|
33
|
GSM777037 500
|
Stromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4
|
Immgen.org, GSE15907
|
8.093E-5
|
6.739E-3
|
5.725E-2
|
2.224E-1
|
6
|
459
|
|
34
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Striatum Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q.Tnr Striatum Top 200 Genes
|
BrainMap
|
1.098E-4
|
8.873E-3
|
7.538E-2
|
3.017E-1
|
5
|
300
|
|
35
|
gudmap developingKidney e15.5 Endothelial cells 1000 k2
|
DevelopingKidney e15.5 Endothelial cells emap-29965 k-means-cluster#2 top-relative-expression-ranked 1000
|
Gudmap Mouse MOE430.2
|
1.150E-4
|
9.031E-3
|
7.673E-2
|
3.161E-1
|
5
|
303
|
|
36
|
Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Subtype polydendrocytes.Bmp4 C1q Top 200 Genes
|
Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Polydendrocyte Subtype polydendrocytes.Bmp4 C1q Top 200 Genes
|
|
1.359E-4
|
1.009E-2
|
8.576E-2
|
3.735E-1
|
5
|
314
|
|
37
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Polydendrocyte Polydendrocyte Subtype Polydendrocyte.polydendrocytes.Bmp4 C1q Top 200 Genes
|
BrainMap
|
1.359E-4
|
1.009E-2
|
8.576E-2
|
3.735E-1
|
5
|
314
|
|
38
|
GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Subtype hProgFPM Top 40 Genes
|
GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hProg Subtype hProgFPM Top 40 Genes
|
GSE76381_EmbryoMoleculeCountsPMLog2
|
1.762E-4
|
1.170E-2
|
9.942E-2
|
4.842E-1
|
3
|
68
|
|
39
|
BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf.Klk6 Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf Subtype Oligodendrocyte.Pdgfa-hi oligodendrocytes.Trf.Klk6 Top 200 Genes
|
BrainMap
|
1.762E-4
|
1.170E-2
|
9.942E-2
|
4.843E-1
|
5
|
332
|
|
40
|
GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 200
|
GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Top 200
|
GSE76381_EmbryoMoleculeCountsPMLog2
|
2.085E-4
|
1.170E-2
|
9.942E-2
|
5.731E-1
|
4
|
184
|
|
41
|
Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Microglia Overall Top 200 Genes
|
Adult Brain Overview (690k cells, 9 regions, 565 cell clusters) BrainAtlas - Mouse McCarroll Microglia Overall Top 200 Genes
|
|
2.085E-4
|
1.170E-2
|
9.942E-2
|
5.731E-1
|
4
|
184
|
|
42
|
GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Overall Top 200 Genes
|
GSE7638 Midbrain human neurons vs stem cell-derived neurons Platform BrainMap - FluidigmC hMgl Overall Top 200 Genes
|
GSE76381_EmbryoMoleculeCountsPMLog2
|
2.085E-4
|
1.170E-2
|
9.942E-2
|
5.731E-1
|
4
|
184
|
|
43
|
BrainMap BrainAtlas - Mouse McCarroll Microglia Microglia Overall Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Microglia Microglia Overall Top 200 Genes
|
BrainMap
|
2.085E-4
|
1.170E-2
|
9.942E-2
|
5.731E-1
|
4
|
184
|
|
44
|
PP HSC 1000 K1
|
PP HSC top-relative-expression-ranked 1000 k-means-cluster#1
|
PCBC
|
2.106E-4
|
1.170E-2
|
9.942E-2
|
5.788E-1
|
5
|
345
|
|
45
|
BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp.Trf Oligodendrocyte.oligodendrocytes.Mbp.Trf Overall Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp.Trf Oligodendrocyte.oligodendrocytes.Mbp.Trf Overall Top 200 Genes
|
BrainMap
|
2.129E-4
|
1.170E-2
|
9.942E-2
|
5.851E-1
|
4
|
185
|
|
46
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. .C1qb Microglia. .C1qb Overall Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. .C1qb Microglia. .C1qb Overall Top 200 Genes
|
BrainMap
|
2.129E-4
|
1.170E-2
|
9.942E-2
|
5.851E-1
|
4
|
185
|
|
47
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. .C1qb Microglia. .C1qb Top 200
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. .C1qb Microglia. .C1qb Top 200
|
BrainMap
|
2.129E-4
|
1.170E-2
|
9.942E-2
|
5.851E-1
|
4
|
185
|
|
48
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. Microglia. Top 200
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. Microglia. Top 200
|
BrainMap
|
2.129E-4
|
1.170E-2
|
9.942E-2
|
5.851E-1
|
4
|
185
|
|
49
|
BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp.Trf Oligodendrocyte.oligodendrocytes.Mbp.Trf Top 200
|
BrainMap BrainAtlas - Mouse McCarroll Oligodendrocyte.oligodendrocytes.Mbp.Trf Oligodendrocyte.oligodendrocytes.Mbp.Trf Top 200
|
BrainMap
|
2.129E-4
|
1.170E-2
|
9.942E-2
|
5.851E-1
|
4
|
185
|
|
50
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. Microglia. Overall Top 200 Genes
|
BrainMap BrainAtlas - Mouse McCarroll Microglia. Microglia. Overall Top 200 Genes
|
BrainMap
|
2.129E-4
|
1.170E-2
|
9.942E-2
|
5.851E-1
|
4
|
185
|
Show 45 more annotations
|
15: Computational [Display Chart]
27 input genes in category / 175 annotations before applied cutoff / 10037 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
M13925 MODULE 86
|
Small monomeric GTPases.
|
MSigDb: C4 - CM: Cancer Modules (v6.0)
|
1.994E-4
|
3.490E-2
|
2.005E-1
|
3.490E-2
|
3
|
43
|
|
16: MicroRNA [Display Chart]
35 input genes in category / 1274 annotations before applied cutoff / 72241 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
hsa-miR-217:PITA
|
hsa-miR-217:PITA TOP
|
PITA
|
4.738E-7
|
5.369E-4
|
4.149E-3
|
6.036E-4
|
5
|
319
|
|
2
|
hsa-miR-137:Non-Functional MTI
|
Non-Functional MTI
|
miRTarbase
|
8.428E-7
|
5.369E-4
|
4.149E-3
|
1.074E-3
|
4
|
148
|
|
3
|
hsa-miR-196a:PITA
|
hsa-miR-196a:PITA TOP
|
PITA
|
2.682E-6
|
8.541E-4
|
6.600E-3
|
3.416E-3
|
4
|
198
|
|
4
|
hsa-miR-196b:PITA
|
hsa-miR-196b:PITA TOP
|
PITA
|
2.682E-6
|
8.541E-4
|
6.600E-3
|
3.416E-3
|
4
|
198
|
|
5
|
hsa-miR-6875-3p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
7.982E-6
|
2.034E-3
|
1.572E-2
|
1.017E-2
|
4
|
261
|
|
6
|
TCTGATA,MIR-361:MSigDB
|
TCTGATA,MIR-361:MSigDB
|
MSigDB
|
1.074E-5
|
2.280E-3
|
1.762E-2
|
1.368E-2
|
3
|
87
|
|
7
|
hsa-miR-548ah-5p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
1.754E-5
|
2.827E-3
|
2.184E-2
|
2.234E-2
|
4
|
319
|
|
8
|
hsa-miR-3609:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
1.775E-5
|
2.827E-3
|
2.184E-2
|
2.261E-2
|
4
|
320
|
|
9
|
hsa-miR-1200:PITA
|
hsa-miR-1200:PITA TOP
|
PITA
|
2.518E-5
|
2.875E-3
|
2.222E-2
|
3.208E-2
|
4
|
350
|
|
10
|
hsa-miR-517a:mirSVR lowEffct
|
hsa-miR-517a:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
2.632E-5
|
2.875E-3
|
2.222E-2
|
3.354E-2
|
4
|
354
|
|
11
|
hsa-miR-154-3p:TargetScan
|
hsa-miR-154-3p
|
TargetScan
|
2.885E-5
|
2.875E-3
|
2.222E-2
|
3.675E-2
|
3
|
121
|
|
12
|
hsa-miR-487a-3p:TargetScan
|
hsa-miR-487a-3p
|
TargetScan
|
2.885E-5
|
2.875E-3
|
2.222E-2
|
3.675E-2
|
3
|
121
|
|
13
|
hsa-miR-410:PITA
|
hsa-miR-410:PITA TOP
|
PITA
|
2.934E-5
|
2.875E-3
|
2.222E-2
|
3.738E-2
|
4
|
364
|
|
14
|
hsa-miR-3200:mirSVR highEffct
|
hsa-miR-3200:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
3.836E-5
|
2.945E-3
|
2.276E-2
|
4.888E-2
|
4
|
390
|
|
15
|
hsa-let-7d*:mirSVR lowEffct
|
hsa-let-7d*:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
4.071E-5
|
2.945E-3
|
2.276E-2
|
5.186E-2
|
4
|
396
|
|
16
|
hsa-miR-553:mirSVR highEffct
|
hsa-miR-553:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
4.274E-5
|
2.945E-3
|
2.276E-2
|
5.445E-2
|
4
|
401
|
|
17
|
CAGTATT,MIR-200C:MSigDB
|
CAGTATT,MIR-200C:MSigDB
|
MSigDB
|
5.804E-5
|
2.945E-3
|
2.276E-2
|
7.395E-2
|
4
|
434
|
|
18
|
CAGTATT,MIR-200B:MSigDB
|
CAGTATT,MIR-200B:MSigDB
|
MSigDB
|
5.804E-5
|
2.945E-3
|
2.276E-2
|
7.395E-2
|
4
|
434
|
|
19
|
CAGTATT,MIR-429:MSigDB
|
CAGTATT,MIR-429:MSigDB
|
MSigDB
|
5.804E-5
|
2.945E-3
|
2.276E-2
|
7.395E-2
|
4
|
434
|
|
20
|
hsa-miR-184:mirSVR lowEffct
|
hsa-miR-184:mirSVR conserved lowEffect-0.1-0.5
|
MicroRNA.org
|
6.175E-5
|
2.945E-3
|
2.276E-2
|
7.866E-2
|
4
|
441
|
|
21
|
hsa-miR-2909:mirSVR highEffct
|
hsa-miR-2909:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
6.338E-5
|
2.945E-3
|
2.276E-2
|
8.075E-2
|
4
|
444
|
|
22
|
hsa-miR-361-5p:Functional MTI
|
Functional MTI
|
miRTarbase
|
6.624E-5
|
2.945E-3
|
2.276E-2
|
8.439E-2
|
3
|
160
|
|
23
|
hsa-miR-452:PITA
|
hsa-miR-452:PITA TOP
|
PITA
|
6.733E-5
|
2.945E-3
|
2.276E-2
|
8.578E-2
|
4
|
451
|
|
24
|
hsa-miR-652-3p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
6.872E-5
|
2.945E-3
|
2.276E-2
|
8.756E-2
|
3
|
162
|
|
25
|
hsa-miR-323b-5p:mirSVR highEffct
|
hsa-miR-323b-5p:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
6.966E-5
|
2.945E-3
|
2.276E-2
|
8.875E-2
|
4
|
455
|
|
26
|
TGAATGT,MIR-181A:MSigDB
|
TGAATGT,MIR-181A:MSigDB
|
MSigDB
|
7.575E-5
|
2.945E-3
|
2.276E-2
|
9.651E-2
|
4
|
465
|
|
27
|
TGAATGT,MIR-181C:MSigDB
|
TGAATGT,MIR-181C:MSigDB
|
MSigDB
|
7.575E-5
|
2.945E-3
|
2.276E-2
|
9.651E-2
|
4
|
465
|
|
28
|
TGAATGT,MIR-181B:MSigDB
|
TGAATGT,MIR-181B:MSigDB
|
MSigDB
|
7.575E-5
|
2.945E-3
|
2.276E-2
|
9.651E-2
|
4
|
465
|
|
29
|
TGAATGT,MIR-181D:MSigDB
|
TGAATGT,MIR-181D:MSigDB
|
MSigDB
|
7.575E-5
|
2.945E-3
|
2.276E-2
|
9.651E-2
|
4
|
465
|
|
30
|
hsa-miR-139-3p:mirSVR lowEffct
|
hsa-miR-139-3p:mirSVR nonconserved lowEffect-0.1-0.5
|
MicroRNA.org
|
8.024E-5
|
2.945E-3
|
2.276E-2
|
1.022E-1
|
4
|
472
|
|
31
|
TGGTGCT,MIR-29B:MSigDB
|
TGGTGCT,MIR-29B:MSigDB
|
MSigDB
|
8.560E-5
|
2.945E-3
|
2.276E-2
|
1.091E-1
|
4
|
480
|
|
32
|
TGGTGCT,MIR-29C:MSigDB
|
TGGTGCT,MIR-29C:MSigDB
|
MSigDB
|
8.560E-5
|
2.945E-3
|
2.276E-2
|
1.091E-1
|
4
|
480
|
|
33
|
TGGTGCT,MIR-29A:MSigDB
|
TGGTGCT,MIR-29A:MSigDB
|
MSigDB
|
8.560E-5
|
2.945E-3
|
2.276E-2
|
1.091E-1
|
4
|
480
|
|
34
|
hsa-miR-320c:PITA
|
hsa-miR-320c:PITA TOP
|
PITA
|
8.629E-5
|
2.945E-3
|
2.276E-2
|
1.099E-1
|
4
|
481
|
|
35
|
hsa-miR-320d:PITA
|
hsa-miR-320d:PITA TOP
|
PITA
|
8.629E-5
|
2.945E-3
|
2.276E-2
|
1.099E-1
|
4
|
481
|
|
36
|
hsa-miR-320b:PITA
|
hsa-miR-320b:PITA TOP
|
PITA
|
8.629E-5
|
2.945E-3
|
2.276E-2
|
1.099E-1
|
4
|
481
|
|
37
|
hsa-miR-320a:PITA
|
hsa-miR-320a:PITA TOP
|
PITA
|
8.629E-5
|
2.945E-3
|
2.276E-2
|
1.099E-1
|
4
|
481
|
|
38
|
hsa-miR-483-3p:Functional MTI
|
Functional MTI
|
miRTarbase
|
8.785E-5
|
2.945E-3
|
2.276E-2
|
1.119E-1
|
3
|
176
|
|
39
|
hsa-miR-518d-3p:mirSVR highEffct
|
hsa-miR-518d-3p:mirSVR nonconserved highEffect-0.5
|
MicroRNA.org
|
9.700E-5
|
3.169E-3
|
2.449E-2
|
1.236E-1
|
3
|
182
|
|
40
|
hsa-miR-146a-5p:Functional MTI
|
Functional MTI
|
miRTarbase
|
1.320E-4
|
4.174E-3
|
3.225E-2
|
1.681E-1
|
3
|
202
|
|
41
|
hsa-miR-4520-2-3p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
1.343E-4
|
4.174E-3
|
3.225E-2
|
1.711E-1
|
2
|
35
|
|
42
|
AAGCAAT,MIR-137:MSigDB
|
AAGCAAT,MIR-137:MSigDB
|
MSigDB
|
1.378E-4
|
4.181E-3
|
3.231E-2
|
1.756E-1
|
3
|
205
|
|
43
|
hsa-miR-4704-5p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
1.848E-4
|
5.405E-3
|
4.176E-2
|
2.354E-1
|
2
|
41
|
|
44
|
hsa-miR-18a-5p:TargetScan
|
hsa-miR-18a-5p
|
TargetScan
|
1.909E-4
|
5.405E-3
|
4.176E-2
|
2.432E-1
|
3
|
229
|
|
45
|
hsa-miR-18b-5p:TargetScan
|
hsa-miR-18b-5p
|
TargetScan
|
1.909E-4
|
5.405E-3
|
4.176E-2
|
2.432E-1
|
3
|
229
|
|
46
|
hsa-miR-133a-5p:Functional MTI (Weak)
|
Functional MTI (Weak)
|
miRTarbase
|
2.034E-4
|
5.583E-3
|
4.314E-2
|
2.591E-1
|
2
|
43
|
|
47
|
hsa-miR-421:Functional MTI
|
Functional MTI
|
miRTarbase
|
2.060E-4
|
5.583E-3
|
4.314E-2
|
2.624E-1
|
3
|
235
|
|
48
|
hsa-miR-1184:PITA
|
hsa-miR-1184:PITA TOP
|
PITA
|
2.164E-4
|
5.744E-3
|
4.439E-2
|
2.757E-1
|
3
|
239
|
|
49
|
hsa-miR-659:PITA
|
hsa-miR-659:PITA TOP
|
PITA
|
2.440E-4
|
6.345E-3
|
4.903E-2
|
3.109E-1
|
3
|
249
|
|
50
|
hsa-miR-582-3p:PITA
|
hsa-miR-582-3p:PITA TOP
|
PITA
|
2.708E-4
|
6.900E-3
|
5.332E-2
|
3.450E-1
|
3
|
258
|
Show 45 more annotations
|
17: Drug [Display Chart]
35 input genes in category / 6938 annotations before applied cutoff / 22841 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
CID000128346
|
mDia
|
Stitch
|
1.065E-18
|
5.542E-15
|
5.221E-14
|
7.390E-15
|
11
|
93
|
|
2
|
CID000004101
|
methenamine silver
|
Stitch
|
1.597E-18
|
5.542E-15
|
5.221E-14
|
1.108E-14
|
13
|
201
|
|
3
|
CID000448043
|
H-1152P
|
Stitch
|
3.557E-16
|
8.226E-13
|
7.750E-12
|
2.468E-12
|
11
|
155
|
|
4
|
CID000005711
|
Y-27632
|
Stitch
|
1.481E-15
|
2.568E-12
|
2.420E-11
|
1.027E-11
|
14
|
445
|
|
5
|
CID000000735
|
geranylgeranyl pyrophosphate
|
Stitch
|
8.702E-15
|
1.115E-11
|
1.051E-10
|
6.037E-11
|
10
|
140
|
|
6
|
CID000003987
|
oleoyl-lysophosphatidic acid
|
Stitch
|
9.646E-15
|
1.115E-11
|
1.051E-10
|
6.693E-11
|
13
|
392
|
|
7
|
CID000003892
|
NSC339663
|
Stitch
|
7.170E-14
|
7.106E-11
|
6.696E-10
|
4.974E-10
|
11
|
250
|
|
8
|
CID000409805
|
NSC23766
|
Stitch
|
1.836E-12
|
1.592E-9
|
1.500E-8
|
1.274E-8
|
8
|
98
|
|
9
|
CID000000449
|
m vs
|
Stitch
|
2.434E-12
|
1.876E-9
|
1.768E-8
|
1.689E-8
|
10
|
245
|
|
10
|
CID000593690
|
B258
|
Stitch
|
6.912E-11
|
4.796E-8
|
4.518E-7
|
4.796E-7
|
4
|
6
|
|
11
|
CID009811606
|
GGTI-298
|
Stitch
|
5.796E-10
|
3.656E-7
|
3.445E-6
|
4.022E-6
|
6
|
64
|
|
12
|
CID009543520
|
triphosphoinositide
|
Stitch
|
6.690E-9
|
3.868E-6
|
3.644E-5
|
4.642E-5
|
8
|
273
|
|
13
|
CID003036508
|
Pc 12
|
Stitch
|
2.806E-8
|
1.497E-5
|
1.411E-4
|
1.947E-4
|
7
|
211
|
|
14
|
ctd:C065536
|
lead titanate zirconate
|
CTD
|
3.289E-8
|
1.590E-5
|
1.498E-4
|
2.282E-4
|
3
|
5
|
|
15
|
CID000001822
|
AC1L1CBF
|
Stitch
|
3.438E-8
|
1.590E-5
|
1.498E-4
|
2.385E-4
|
8
|
337
|
|
16
|
CID004369374
|
AC1N9ZZC
|
Stitch
|
9.671E-8
|
4.194E-5
|
3.951E-4
|
6.710E-4
|
6
|
149
|
|
17
|
ctd:D006160
|
Guanosine Triphosphate
|
CTD
|
1.831E-7
|
7.473E-5
|
7.041E-4
|
1.270E-3
|
4
|
33
|
|
18
|
CID000168005
|
Te Al
|
Stitch
|
2.338E-7
|
9.012E-5
|
8.491E-4
|
1.622E-3
|
4
|
35
|
|
19
|
CID000004122
|
nocodazole
|
Stitch
|
4.971E-7
|
1.796E-4
|
1.693E-3
|
3.449E-3
|
8
|
478
|
|
20
|
CID006857406
|
AC1OAGKB
|
Stitch
|
5.178E-7
|
1.796E-4
|
1.693E-3
|
3.593E-3
|
6
|
198
|
|
21
|
CID006433489
|
escina
|
Stitch
|
6.003E-7
|
1.893E-4
|
1.784E-3
|
4.165E-3
|
4
|
44
|
|
22
|
CID000425429
|
AC1L8FNU
|
Stitch
|
6.003E-7
|
1.893E-4
|
1.784E-3
|
4.165E-3
|
4
|
44
|
|
23
|
ctd:D000068296
|
Risedronate Sodium
|
CTD
|
1.186E-6
|
3.577E-4
|
3.371E-3
|
8.228E-3
|
3
|
14
|
|
24
|
ctd:C488583
|
Clostridium difficile lethal toxin B
|
CTD
|
1.821E-6
|
5.053E-4
|
4.761E-3
|
1.263E-2
|
3
|
16
|
|
25
|
CID000002507
|
AC1L1DU2
|
Stitch
|
1.821E-6
|
5.053E-4
|
4.761E-3
|
1.263E-2
|
3
|
16
|
|
26
|
ctd:D016244
|
Guanosine 5'-O-(3-Thiotriphosphate)
|
CTD
|
2.208E-6
|
5.893E-4
|
5.553E-3
|
1.532E-2
|
3
|
17
|
|
27
|
ctd:C487513
|
NSC 23766
|
CTD
|
2.647E-6
|
6.803E-4
|
6.410E-3
|
1.837E-2
|
3
|
18
|
|
28
|
CID000644262
|
B-Go
|
Stitch
|
3.691E-6
|
9.145E-4
|
8.617E-3
|
2.561E-2
|
3
|
20
|
|
29
|
ctd:C063007
|
exoenzyme C3, Clostridium botulinum
|
CTD
|
7.407E-6
|
1.759E-3
|
1.657E-2
|
5.139E-2
|
3
|
25
|
|
30
|
CID000520535
|
superoxide
|
Stitch
|
8.006E-6
|
1.759E-3
|
1.657E-2
|
5.554E-2
|
7
|
490
|
|
31
|
CID004273754
|
JWH-015
|
Stitch
|
8.365E-6
|
1.759E-3
|
1.657E-2
|
5.803E-2
|
3
|
26
|
|
32
|
CID004369498
|
A-A-X
|
Stitch
|
8.365E-6
|
1.759E-3
|
1.657E-2
|
5.803E-2
|
3
|
26
|
|
33
|
CID009842077
|
2-acetamido-3-[(1Z,3Z,6Z)-3,7,11-trimethyldodeca-1,3,6,10-tetraenyl]sulfanyl-propanoic acid
|
Stitch
|
8.365E-6
|
1.759E-3
|
1.657E-2
|
5.803E-2
|
3
|
26
|
|
34
|
CID001172104
|
Src kinase inhibitor II
|
Stitch
|
1.366E-5
|
2.787E-3
|
2.626E-2
|
9.477E-2
|
2
|
4
|
|
35
|
CID003005531
|
FTI-277
|
Stitch
|
2.054E-5
|
4.020E-3
|
3.788E-2
|
1.425E-1
|
4
|
106
|
|
36
|
CID003012116
|
GGTI-286
|
Stitch
|
2.086E-5
|
4.020E-3
|
3.788E-2
|
1.447E-1
|
3
|
35
|
|
37
|
CID000161743
|
Y 221
|
Stitch
|
2.274E-5
|
4.265E-3
|
4.018E-2
|
1.578E-1
|
2
|
5
|
|
38
|
CID000002712
|
chlordiazepoxide
|
Stitch
|
2.735E-5
|
4.993E-3
|
4.704E-2
|
1.897E-1
|
4
|
114
|
|
39
|
CID004210951
|
SB415286
|
Stitch
|
2.900E-5
|
5.079E-3
|
4.785E-2
|
2.012E-1
|
3
|
39
|
|
40
|
CID003476986
|
blebbistatin
|
Stitch
|
2.928E-5
|
5.079E-3
|
4.785E-2
|
2.031E-1
|
4
|
116
|
|
41
|
CID000002067
|
N-acetyl-S-geranylgeranyl-L-cysteine
|
Stitch
|
3.632E-5
|
6.146E-3
|
5.790E-2
|
2.520E-1
|
3
|
42
|
|
42
|
CID000000706
|
farnesol pyrophosphate
|
Stitch
|
3.803E-5
|
6.282E-3
|
5.919E-2
|
2.639E-1
|
4
|
124
|
|
43
|
CID000003800
|
NSC613009
|
Stitch
|
4.714E-5
|
7.350E-3
|
6.925E-2
|
3.270E-1
|
4
|
131
|
|
44
|
CID005319895
|
AC1NSYSB
|
Stitch
|
4.767E-5
|
7.350E-3
|
6.925E-2
|
3.307E-1
|
2
|
7
|
|
45
|
CID000011762
|
BINOL
|
Stitch
|
4.767E-5
|
7.350E-3
|
6.925E-2
|
3.307E-1
|
2
|
7
|
|
46
|
CID002777991
|
i 143
|
Stitch
|
6.350E-5
|
8.991E-3
|
8.472E-2
|
4.406E-1
|
2
|
8
|
|
47
|
CID009890888
|
GGTI-2147
|
Stitch
|
6.350E-5
|
8.991E-3
|
8.472E-2
|
4.406E-1
|
2
|
8
|
|
48
|
ctd:C452601
|
sulindac derivative IND 12
|
CTD
|
6.350E-5
|
8.991E-3
|
8.472E-2
|
4.406E-1
|
2
|
8
|
|
49
|
ctd:C468114
|
1-palmitoyl-2-arachidonyl-3-phosphorylcholine
|
CTD
|
6.350E-5
|
8.991E-3
|
8.472E-2
|
4.406E-1
|
2
|
8
|
|
50
|
ctd:D009240
|
N-Formylmethionine Leucyl-Phenylalanine
|
CTD
|
6.526E-5
|
9.023E-3
|
8.501E-2
|
4.528E-1
|
3
|
51
|
Show 45 more annotations
|
18: Disease [Display Chart]
33 input genes in category / 540 annotations before applied cutoff / 16205 genes in category
|
|
ID |
Name |
Source |
pValue |
FDR B&H |
FDR B&Y |
Bonferroni |
Genes from Input
|
Genes in Annotation
|
|
1
|
C0265268
|
Adams Oliver syndrome
|
DisGeNET Curated
|
1.006E-8
|
5.430E-6
|
3.730E-5
|
5.430E-6
|
4
|
13
|
|
2
|
C0175701
|
Aarskog syndrome
|
DisGeNET Curated
|
4.279E-7
|
1.155E-4
|
7.937E-4
|
2.311E-4
|
3
|
8
|
|
3
|
C1845667
|
RETINITIS PIGMENTOSA 3
|
DisGeNET Curated
|
8.392E-5
|
1.476E-2
|
1.014E-1
|
4.531E-2
|
2
|
7
|
|
4
|
C0393576
|
Chorea Acanthocytosis Syndrome
|
DisGeNET Curated
|
1.435E-4
|
1.476E-2
|
1.014E-1
|
7.748E-2
|
2
|
9
|
|
5
|
C2960129
|
Vanishing white matter disease
|
DisGeNET BeFree
|
1.435E-4
|
1.476E-2
|
1.014E-1
|
7.748E-2
|
2
|
9
|
|
6
|
C0398738
|
Leukocyte adhesion deficiency type 1
|
DisGeNET Curated
|
1.982E-4
|
1.476E-2
|
1.014E-1
|
1.070E-1
|
3
|
56
|
|
7
|
C0025269
|
Multiple Endocrine Neoplasia Type 2b
|
DisGeNET Curated
|
2.187E-4
|
1.476E-2
|
1.014E-1
|
1.181E-1
|
2
|
11
|
|
8
|
C1859974
|
GLUCOCORTICOID DEFICIENCY 1
|
DisGeNET Curated
|
2.187E-4
|
1.476E-2
|
1.014E-1
|
1.181E-1
|
2
|
11
|
|
9
|
C0342731
|
Deficiency of mevalonate kinase
|
DisGeNET Curated
|
3.093E-4
|
1.742E-2
|
1.197E-1
|
1.670E-1
|
2
|
13
|
|
10
|
C1535939
|
Pneumocystis jiroveci pneumonia
|
DisGeNET BeFree
|
3.226E-4
|
1.742E-2
|
1.197E-1
|
1.742E-1
|
3
|
66
|
|
11
|
C1318518
|
Infantile malignant osteopetrosis
|
DisGeNET Curated
|
3.604E-4
|
1.769E-2
|
1.215E-1
|
1.946E-1
|
2
|
14
|
|
12
|
C0162678
|
Neurofibromatoses
|
DisGeNET Curated
|
4.002E-4
|
1.801E-2
|
1.237E-1
|
2.161E-1
|
3
|
71
|
|
13
|
C3539920
|
ECTODERMAL DYSPLASIA 11B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE
|
DisGeNET Curated
|
5.366E-4
|
1.932E-2
|
1.327E-1
|
2.897E-1
|
2
|
17
|
|
14
|
C3887494
|
ECTODERMAL DYSPLASIA 10B, HYPOHIDROTIC/HAIR/TOOTH TYPE, AUTOSOMAL RECESSIVE
|
DisGeNET Curated
|
5.366E-4
|
1.932E-2
|
1.327E-1
|
2.897E-1
|
2
|
17
|
|
15
|
C0010418
|
Cryptosporidiosis
|
DisGeNET BeFree
|
5.366E-4
|
1.932E-2
|
1.327E-1
|
2.897E-1
|
2
|
17
|
|
16
|
C1859807
|
AMYOTROPHIC LATERAL SCLEROSIS 2, JUVENILE (disorder)
|
DisGeNET Curated
|
6.729E-4
|
2.244E-2
|
1.542E-1
|
3.634E-1
|
2
|
19
|
|
17
|
C0343401
|
MRSA - Methicillin resistant Staphylococcus aureus infection
|
DisGeNET BeFree
|
8.813E-4
|
2.244E-2
|
1.542E-1
|
4.759E-1
|
3
|
93
|
|
18
|
C0039292
|
Tangier Disease
|
DisGeNET Curated
|
9.056E-4
|
2.244E-2
|
1.542E-1
|
4.890E-1
|
2
|
22
|
|
19
|
C0003838
|
Arterial Occlusive Diseases
|
DisGeNET Curated
|
9.906E-4
|
2.244E-2
|
1.542E-1
|
5.349E-1
|
2
|
23
|
|
20
|
C1858991
|
Childhood Ataxia with Central Nervous System Hypomyelinization
|
DisGeNET Curated
|
1.079E-3
|
2.244E-2
|
1.542E-1
|
5.828E-1
|
2
|
24
|
|
21
|
C0339528
|
X-linked retinitis pigmentosa
|
DisGeNET BeFree
|
1.172E-3
|
2.244E-2
|
1.542E-1
|
6.327E-1
|
2
|
25
|
|
22
|
C0162359
|
Christ-Siemens-Touraine syndrome
|
DisGeNET Curated
|
1.688E-3
|
2.244E-2
|
1.542E-1
|
9.115E-1
|
2
|
30
|
|
23
|
C0085084
|
Motor Neuron Disease
|
DisGeNET Curated
|
1.709E-3
|
2.244E-2
|
1.542E-1
|
9.228E-1
|
3
|
117
|
|
24
|
C0024312
|
Lymphopenia
|
DisGeNET Curated
|
1.837E-3
|
2.244E-2
|
1.542E-1
|
9.922E-1
|
3
|
120
|
|
25
|
C0033687
|
Proteinuria
|
DisGeNET Curated
|
2.018E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
3
|
124
|
|
26
|
C4023093
|
Abnormality of neutrophil physiology
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
27
|
cv:C1842398
|
Neutrophil immunodeficiency syndrome
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
28
|
cv:CN219578
|
Focal segmental glomerulosclerosis 8
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
29
|
cv:CN189147
|
Epileptic encephalopathy, early infantile, 23
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
30
|
C3873531
|
Phagocytic immunodeficiency
|
DisGeNET BeFree
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
31
|
cv:C0399440
|
Hereditary gingival fibromatosis
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
32
|
20081125:Reiman
|
APOE*e4 carriers with late onset Alzheimer's disease
|
GWAS
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
33
|
C4225328
|
IMMUNODEFICIENCY 40
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
34
|
C1853120
|
Noonan Syndrome 4
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
35
|
C0549423
|
Obstructive Hydrocephalus
|
DisGeNET BeFree
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
36
|
C4014492
|
EPILEPTIC ENCEPHALOPATHY, EARLY INFANTILE, 23
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
37
|
OMIN:608203
|
NEUTROPHIL IMMUNODEFICIENCY SYNDROME
|
OMIM
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
38
|
cv:CN028867
|
Adams-Oliver syndrome 1
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
39
|
cv:C3280182
|
Adams-Oliver syndrome 2
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
40
|
C4014993
|
FOCAL SEGMENTAL GLOMERULOSCLEROSIS 8
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
41
|
cv:C3279842
|
Mental retardation, autosomal dominant 2
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
42
|
cv:C1968689
|
Hyperimmunoglobulin E recurrent infection syndrome, autosomal recessive
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
43
|
C1842398
|
Neutrophil Immunodeficiency Syndrome
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
44
|
OMIN:243700
|
HYPER-IgE RECURRENT INFECTION SYNDROME, AUTOSOMAL RECESSIVE
|
OMIM
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
45
|
C4225222
|
TAKENOUCHI-KOSAKI SYNDROME
|
DisGeNET Curated
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
46
|
C1838652
|
SPLIT-HAND/FOOT MALFORMATION 3
|
DisGeNET BeFree
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
47
|
OMIN:610733
|
NOONAN SYNDROME 4; NS4
|
OMIM
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
48
|
C0741146
|
anxiety acute
|
DisGeNET BeFree
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
49
|
cv:C1853120
|
Noonan syndrome 4
|
Clinical Variations
|
2.036E-3
|
2.244E-2
|
1.542E-1
|
1.000E0
|
1
|
1
|
|
50
|
C0079504
|
Hermanski-Pudlak Syndrome
|
DisGeNET BeFree
|
3.606E-3
|
3.889E-2
|
2.672E-1
|
1.000E0
|
2
|
44
|
Show 45 more annotations
|
|