Toppgene analysis for Wikipedia protein communities, toppgene analysis, cc76_9, positive side

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1: GO: Molecular Function [Display Chart] 9 input genes in category / 51 annotations before applied cutoff / 18661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0004869 cysteine-type endopeptidase inhibitor activity 3.370E-4 1.230E-2
5.556E-2
 1.719E-2 2 58
2 GO:1902118 calcidiol binding 4.823E-4 1.230E-2
5.556E-2
 2.460E-2 1 1
3 GO:0030294 receptor signaling protein tyrosine kinase inhibitor activity 9.644E-4 1.230E-2
5.556E-2
 4.918E-2 1 2
4 GO:1902271 D3 vitamins binding 9.644E-4 1.230E-2
5.556E-2
 4.918E-2 1 2
5 GO:0030984 kininogen binding 1.928E-3 1.805E-2
8.158E-2
9.832E-2
 1 4
6 GO:0030292 protein tyrosine kinase inhibitor activity 2.409E-3 1.805E-2
8.158E-2
1.229E-1
 1 5
7 GO:0004866 endopeptidase inhibitor activity 2.881E-3 1.805E-2
8.158E-2
1.469E-1
 2 171
8 GO:0061135 endopeptidase regulator activity 3.083E-3 1.805E-2
8.158E-2
1.572E-1
 2 177
9 GO:0030414 peptidase inhibitor activity 3.186E-3 1.805E-2
8.158E-2
1.625E-1
 2 180
10 GO:0005499 vitamin D binding 3.853E-3 1.965E-2
8.879E-2
1.965E-1
 1 8
11 GO:0004252 serine-type endopeptidase activity 4.510E-3 2.040E-2
9.219E-2
2.300E-1
 2 215
12 GO:0061134 peptidase regulator activity 4.800E-3 2.040E-2
9.219E-2
2.448E-1
 2 222
13 GO:0008236 serine-type peptidase activity 5.678E-3 2.119E-2
9.573E-2
2.896E-1
 2 242
14 GO:0017171 serine hydrolase activity 5.815E-3 2.119E-2
9.573E-2
2.966E-1
 2 245
15 GO:0015643 toxic substance binding 6.733E-3 2.146E-2
9.698E-2
3.434E-1
 1 14
16 GO:0008191 metalloendopeptidase inhibitor activity 6.733E-3 2.146E-2
9.698E-2
3.434E-1
 1 14
17 GO:0051393 alpha-actinin binding 1.200E-2 3.599E-2
1.626E-1
6.118E-1
 1 25
18 GO:0004857 enzyme inhibitor activity 1.444E-2 4.092E-2
1.849E-1
7.365E-1
 2 393
19 GO:0030507 spectrin binding 1.533E-2 4.115E-2
1.860E-1
7.819E-1
 1 32
20 GO:0043394 proteoglycan binding 1.676E-2 4.185E-2
1.891E-1
8.546E-1
 1 35
21 GO:0042805 actinin binding 1.723E-2 4.185E-2
1.891E-1
8.789E-1
 1 36
22 GO:0004175 endopeptidase activity 1.922E-2 4.456E-2
2.014E-1
9.804E-1
 2 457
23 GO:0005504 fatty acid binding 2.245E-2 4.977E-2
2.249E-1
1.000E0
 1 47
Show 18 more annotations

2: GO: Biological Process [Display Chart] 9 input genes in category / 282 annotations before applied cutoff / 18623 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0002576 platelet degranulation 1.511E-5 4.260E-3 2.650E-2 4.260E-3 3 107
2 GO:0006953 acute-phase response 3.154E-4 1.721E-2
1.071E-1
8.895E-2
 2 56
3 GO:0045055 regulated exocytosis 3.733E-4 1.721E-2
1.071E-1
1.053E-1
 3 315
4 GO:0032835 glomerulus development 4.121E-4 1.721E-2
1.071E-1
1.162E-1
 2 64
5 GO:0030574 collagen catabolic process 4.516E-4 1.721E-2
1.071E-1
1.274E-1
 2 67
6 GO:0021730 trigeminal sensory nucleus development 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
7 GO:0044179 hemolysis in other organism 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
8 GO:0019836 hemolysis by symbiont of host erythrocytes 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
9 GO:0051659 maintenance of mitochondrion location 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
10 GO:0001897 cytolysis by symbiont of host cells 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
11 GO:0052331 hemolysis in other organism involved in symbiotic interaction 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
12 GO:0051715 cytolysis in other organism 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
13 GO:0051801 cytolysis in other organism involved in symbiotic interaction 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
14 GO:0002121 inter-male aggressive behavior 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
15 GO:0021740 principal sensory nucleus of trigeminal nerve development 9.663E-4 1.721E-2
1.071E-1
2.725E-1
 1 2
16 GO:0006887 exocytosis 9.766E-4 1.721E-2
1.071E-1
2.754E-1
 3 438
17 GO:0070541 response to platinum ion 1.449E-3 2.330E-2
1.449E-1
4.087E-1
 1 3
18 GO:0032963 collagen metabolic process 1.487E-3 2.330E-2
1.449E-1
4.193E-1
 2 122
19 GO:0072006 nephron development 2.063E-3 3.062E-2
1.905E-1
5.817E-1
 2 144
20 GO:0002526 acute inflammatory response 2.507E-3 3.535E-2
2.199E-1
7.070E-1
 2 159
21 GO:0001907 killing by symbiont of host cells 2.897E-3 3.587E-2
2.232E-1
8.168E-1
 1 6
22 GO:0044004 disruption by symbiont of host cell 2.897E-3 3.587E-2
2.232E-1
8.168E-1
 1 6
23 GO:0051701 interaction with host 2.926E-3 3.587E-2
2.232E-1
8.251E-1
 2 172
24 GO:0007519 skeletal muscle tissue development 3.483E-3 4.093E-2
2.546E-1
9.822E-1
 2 188
25 GO:0060538 skeletal muscle organ development 3.855E-3 4.348E-2
2.705E-1
1.000E0
 2 198
26 GO:0051657 maintenance of organelle location 4.342E-3 4.373E-2
2.720E-1
1.000E0
 1 9
27 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep 4.342E-3 4.373E-2
2.720E-1
1.000E0
 1 9
28 GO:0002118 aggressive behavior 4.342E-3 4.373E-2
2.720E-1
1.000E0
 1 9
29 GO:0007565 female pregnancy 4.610E-3 4.388E-2
2.730E-1
1.000E0
 2 217
30 GO:0072102 glomerulus morphogenesis 4.823E-3 4.388E-2
2.730E-1
1.000E0
 1 10
31 GO:0032836 glomerular basement membrane development 4.823E-3 4.388E-2
2.730E-1
1.000E0
 1 10
32 GO:0072015 glomerular visceral epithelial cell development 5.305E-3 4.632E-2
2.882E-1
1.000E0
 1 11
33 GO:0001894 tissue homeostasis 5.519E-3 4.632E-2
2.882E-1
1.000E0
 2 238
34 GO:0072310 glomerular epithelial cell development 5.786E-3 4.632E-2
2.882E-1
1.000E0
 1 12
35 GO:0010951 negative regulation of endopeptidase activity 5.839E-3 4.632E-2
2.882E-1
1.000E0
 2 245
36 GO:0044706 multi-multicellular organism process 6.072E-3 4.632E-2
2.882E-1
1.000E0
 2 250
37 GO:0097067 cellular response to thyroid hormone stimulus 6.266E-3 4.632E-2
2.882E-1
1.000E0
 1 13
38 GO:0045938 positive regulation of circadian sleep/wake cycle, sleep 6.266E-3 4.632E-2
2.882E-1
1.000E0
 1 13
39 GO:0010466 negative regulation of peptidase activity 6.406E-3 4.632E-2
2.882E-1
1.000E0
 2 257
40 GO:0045188 regulation of circadian sleep/wake cycle, non-REM sleep 6.747E-3 4.757E-2
2.959E-1
1.000E0
 1 14
41 GO:0042748 circadian sleep/wake cycle, non-REM sleep 7.227E-3 4.867E-2
3.028E-1
1.000E0
 1 15
42 GO:0071496 cellular response to external stimulus 8.093E-3 4.867E-2
3.028E-1
1.000E0
 2 290
43 GO:0001822 kidney development 8.147E-3 4.867E-2
3.028E-1
1.000E0
 2 291
44 GO:0051818 disruption of cells of other organism involved in symbiotic interaction 8.187E-3 4.867E-2
3.028E-1
1.000E0
 1 17
45 GO:0046689 response to mercury ion 8.187E-3 4.867E-2
3.028E-1
1.000E0
 1 17
46 GO:0051883 killing of cells in other organism involved in symbiotic interaction 8.187E-3 4.867E-2
3.028E-1
1.000E0
 1 17
47 GO:0072112 glomerular visceral epithelial cell differentiation 8.667E-3 4.867E-2
3.028E-1
1.000E0
 1 18
48 GO:0071711 basement membrane organization 8.667E-3 4.867E-2
3.028E-1
1.000E0
 1 18
49 GO:0061318 renal filtration cell differentiation 8.667E-3 4.867E-2
3.028E-1
1.000E0
 1 18
50 GO:0046852 positive regulation of bone remodeling 9.147E-3 4.867E-2
3.028E-1
1.000E0
 1 19
Show 45 more annotations

3: GO: Cellular Component [Display Chart] 9 input genes in category / 32 annotations before applied cutoff / 19061 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 GO:0072562 blood microparticle 3.717E-7 1.189E-5 4.827E-5 1.189E-5 4 143
2 GO:0031093 platelet alpha granule lumen 1.886E-6 3.018E-5 1.225E-4 6.036E-5 3 55
3 GO:0031091 platelet alpha granule 4.832E-6 5.154E-5 2.092E-4 1.546E-4 3 75
4 GO:0034774 secretory granule lumen 7.051E-6 5.641E-5 2.289E-4 2.256E-4 3 85
5 GO:0060205 cytoplasmic vesicle lumen 1.294E-5 7.731E-5 3.138E-4 4.142E-4 3 104
6 GO:0031983 vesicle lumen 1.450E-5 7.731E-5 3.138E-4 4.639E-4 3 108
7 GO:0030141 secretory granule 7.013E-4 2.971E-3 1.206E-2 2.244E-2 3 400
8 GO:0043202 lysosomal lumen 7.428E-4 2.971E-3 1.206E-2 2.377E-2 2 88
9 GO:0031012 extracellular matrix 9.498E-4 3.377E-3 1.371E-2 3.039E-2 3 444
10 GO:0005775 vacuolar lumen 1.285E-3 4.113E-3 1.669E-2 4.113E-2 2 116
11 GO:0036021 endolysosome lumen 1.887E-3 5.491E-3 2.228E-2
6.040E-2
 1 4
12 GO:0036056 filtration diaphragm 3.772E-3 9.284E-3 3.768E-2
1.207E-1
 1 8
13 GO:0036057 slit diaphragm 3.772E-3 9.284E-3 3.768E-2
1.207E-1
 1 8
14 GO:0036019 endolysosome 8.000E-3 1.829E-2
7.421E-2
2.560E-1
 1 17
15 GO:0098857 membrane microdomain 1.069E-2 2.138E-2
8.678E-2
3.421E-1
 2 343
16 GO:0045121 membrane raft 1.069E-2 2.138E-2
8.678E-2
3.421E-1
 2 343
17 GO:0031904 endosome lumen 1.221E-2 2.299E-2
9.330E-2
3.908E-1
 1 26
18 GO:0043198 dendritic shaft 2.798E-2 4.975E-2
2.019E-1
8.954E-1
 1 60
Show 13 more annotations

4: Human Phenotype [Display Chart] 4 input genes in category / 134 annotations before applied cutoff / 4707 genes in category

No results to display

5: Mouse Phenotype [Display Chart] 8 input genes in category / 264 annotations before applied cutoff / 10355 genes in category

No results to display

6: Domain [Display Chart] 9 input genes in category / 81 annotations before applied cutoff / 18735 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 PS01254 FETUIN 1 PROSITE 2.051E-7 8.308E-6 4.136E-5 1.662E-5 2 2
2 PS01255 FETUIN 2 PROSITE 2.051E-7 8.308E-6 4.136E-5 1.662E-5 2 2
3 IPR001363 Prot inh fetuin CS InterPro 6.153E-7 1.107E-5 5.511E-5 4.984E-5 2 3
4 SM00103 ALBUMIN SMART 1.230E-6 1.107E-5 5.511E-5 9.965E-5 2 4
5 PS51438 ALBUMIN 2 PROSITE 1.230E-6 1.107E-5 5.511E-5 9.965E-5 2 4
6 PF00273 Serum albumin Pfam 1.230E-6 1.107E-5 5.511E-5 9.965E-5 2 4
7 IPR014760 Serum albumin N InterPro 1.230E-6 1.107E-5 5.511E-5 9.965E-5 2 4
8 IPR020857 Serum albumin CS InterPro 1.230E-6 1.107E-5 5.511E-5 9.965E-5 2 4
9 PS00212 ALBUMIN 1 PROSITE 1.230E-6 1.107E-5 5.511E-5 9.965E-5 2 4
10 IPR020858 Serum albumin-like InterPro 2.050E-6 1.660E-5 8.265E-5 1.660E-4 2 5
11 IPR000264 ALB/AFP/VDB InterPro 3.074E-6 2.264E-5 1.127E-4 2.490E-4 2 6
12 SM00043 CY SMART 2.779E-5 1.809E-4 9.003E-4 2.251E-3 2 17
13 PF00031 Cystatin Pfam 3.126E-5 1.809E-4 9.003E-4 2.532E-3 2 18
14 IPR000010 Cystatin dom InterPro 3.126E-5 1.809E-4 9.003E-4 2.532E-3 2 18
15 PF08205 C2-set 2 Pfam 1.666E-4 8.433E-4 4.198E-3 1.349E-2 2 41
16 IPR013162 CD80 C2-set InterPro 1.666E-4 8.433E-4 4.198E-3 1.349E-2 2 41
17 PF09164 VitD-bind III Pfam 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
18 PF08127 Propeptide C1 Pfam 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
19 IPR025760 Cystatin Fetuin A InterPro 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
20 IPR012599 Propeptide C1A InterPro 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
21 IPR015247 VitD-bind III InterPro 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
22 PS51530 CYSTATIN FETUIN B PROSITE 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
23 IPR000213 VitD-bd InterPro 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
24 IPR025764 Cystatin Fetuin B InterPro 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
25 IPR028705 Stromelysin-3 InterPro 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
26 PS51529 CYSTATIN FETUIN A PROSITE 4.804E-4 1.497E-3 7.450E-3 3.891E-2 1 1
27 IPR001500 A1A glycop InterPro 9.606E-4 2.882E-3 1.434E-2
7.781E-2
 1 2
28 IPR021177 Serum albumin/AFP/Afamin InterPro 1.441E-3 4.167E-3 2.074E-2
1.167E-1
 1 3
29 PF07686 V-set Pfam 3.336E-3 9.183E-3 4.571E-2
2.702E-1
 2 185
30 PF07679 I-set Pfam 3.515E-3 9.183E-3 4.571E-2
2.847E-1
 2 190
31 IPR013098 Ig I-set InterPro 3.515E-3 9.183E-3 4.571E-2
2.847E-1
 2 190
32 IPR013106 Ig V-set InterPro 3.886E-3 9.835E-3 4.896E-2
3.147E-1
 2 200
33 IPR025661 Pept asp AS InterPro 4.795E-3 1.177E-2
5.858E-2
3.884E-1
 1 10
34 IPR025660 Pept his AS InterPro 5.273E-3 1.197E-2
5.961E-2
4.271E-1
 1 11
35 IPR003598 Ig sub2 InterPro 5.322E-3 1.197E-2
5.961E-2
4.311E-1
 2 235
36 SM00408 IGc2 SMART 5.322E-3 1.197E-2
5.961E-2
4.311E-1
 2 235
37 PF00112 Peptidase C1 Pfam 6.229E-3 1.261E-2
6.279E-2
5.046E-1
 1 13
38 IPR000668 Peptidase C1A C InterPro 6.229E-3 1.261E-2
6.279E-2
5.046E-1
 1 13
39 IPR013128 Peptidase C1A InterPro 6.229E-3 1.261E-2
6.279E-2
5.046E-1
 1 13
40 SM00645 Pept C1 SMART 6.229E-3 1.261E-2
6.279E-2
5.046E-1
 1 13
41 IPR021158 Pept M10A Zn BS InterPro 7.184E-3 1.419E-2
7.065E-2
5.819E-1
 1 15
42 PS00213 LIPOCALIN PROSITE 8.139E-3 1.533E-2
7.632E-2
6.592E-1
 1 17
43 IPR018486 Hemopexin CS InterPro 8.139E-3 1.533E-2
7.632E-2
6.592E-1
 1 17
44 IPR016293 Pept M10A stromelysin-type InterPro 8.616E-3 1.551E-2
7.720E-2
6.979E-1
 1 18
45 IPR002345 Lipocalin InterPro 8.616E-3 1.551E-2
7.720E-2
6.979E-1
 1 18
46 IPR033739 M10A MMP InterPro 1.100E-2 1.650E-2
8.211E-2
8.908E-1
 1 23
47 PS51642 HEMOPEXIN 2 PROSITE 1.100E-2 1.650E-2
8.211E-2
8.908E-1
 1 23
48 SM00120 HX SMART 1.100E-2 1.650E-2
8.211E-2
8.908E-1
 1 23
49 2.110.10.10 - Gene3D 1.100E-2 1.650E-2
8.211E-2
8.908E-1
 1 23
50 IPR018487 Hemopexin-like repeat InterPro 1.100E-2 1.650E-2
8.211E-2
8.908E-1
 1 23
Show 45 more annotations

7: Pathway [Display Chart] 8 input genes in category / 44 annotations before applied cutoff / 12450 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 1269367 Platelet degranulation BioSystems: REACTOME 6.275E-5 1.216E-3 5.318E-3 2.761E-3 3 132
2 1269365 Response to elevated platelet cytosolic Ca2+ BioSystems: REACTOME 7.011E-5 1.216E-3 5.318E-3 3.085E-3 3 137
3 1270243 Nephrin interactions BioSystems: REACTOME 8.293E-5 1.216E-3 5.318E-3 3.649E-3 2 22
4 1270259 Collagen degradation BioSystems: REACTOME 2.926E-4 3.218E-3 1.407E-2 1.287E-2 2 41
5 1269350 Platelet activation, signaling and aggregation BioSystems: REACTOME 5.918E-4 4.039E-3 1.766E-2 2.604E-2 3 282
6 1309189 Defective SLCO1B1 causes hyperbilirubinemia, Rotor type (HBLRR) BioSystems: REACTOME 6.426E-4 4.039E-3 1.766E-2 2.827E-2 1 1
7 1309191 Defective SLCO1B3 causes hyperbilirubinemia, Rotor type (HBLRR) BioSystems: REACTOME 6.426E-4 4.039E-3 1.766E-2 2.827E-2 1 1
8 1270257 Degradation of the extracellular matrix BioSystems: REACTOME 2.168E-3 1.192E-2
5.214E-2
9.538E-2
 2 112
9 1457780 Neutrophil degranulation BioSystems: REACTOME 2.960E-3 1.358E-2
5.937E-2
1.303E-1
 3 492
10 1270231 Cell-Cell communication BioSystems: REACTOME 3.086E-3 1.358E-2
5.937E-2
1.358E-1
 2 134
11 1270052 Vitamin D (calciferol) metabolism BioSystems: REACTOME 4.490E-3 1.646E-2
7.200E-2
1.976E-1
 1 7
12 1309123 SLC transporter disorders BioSystems: REACTOME 4.490E-3 1.646E-2
7.200E-2
1.976E-1
 1 7
13 P04396 Vitamin D metabolism and pathway PantherDB 5.770E-3 1.953E-2
8.540E-2
2.539E-1
 1 9
14 1269943 Transport of organic anions BioSystems: REACTOME 7.687E-3 2.416E-2
1.056E-1
3.382E-1
 1 12
15 1269205 Trafficking and processing of endosomal TLR BioSystems: REACTOME 8.963E-3 2.597E-2
1.136E-1
3.944E-1
 1 14
16 M3468 Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix MSigDB C2 BIOCARTA (v6.0) 9.444E-3 2.597E-2
1.136E-1
4.155E-1
 2 238
17 1270045 Recycling of bile acids and salts BioSystems: REACTOME 1.024E-2 2.650E-2
1.159E-1
4.505E-1
 1 16
18 1269898 Scavenging of heme from plasma BioSystems: REACTOME 1.215E-2 2.960E-2
1.294E-1
5.345E-1
 1 19
19 1270007 HDL-mediated lipid transport BioSystems: REACTOME 1.278E-2 2.960E-2
1.294E-1
5.624E-1
 1 20
20 1270244 Extracellular matrix organization BioSystems: REACTOME 1.453E-2 3.198E-2
1.398E-1
6.395E-1
 2 298
21 138072 Nephrin/Neph1 signaling in the kidney podocyte BioSystems: Pathway Interaction Database 1.659E-2 3.476E-2
1.520E-1
7.300E-1
 1 26
22 1270258 Activation of Matrix Metalloproteinases BioSystems: REACTOME 2.101E-2 4.203E-2
1.838E-1
9.247E-1
 1 33
23 137948 BMP receptor signaling BioSystems: Pathway Interaction Database 2.291E-2 4.382E-2
1.916E-1
1.000E0
 1 36
24 1269939 Transport of vitamins, nucleosides, and related molecules BioSystems: REACTOME 2.542E-2 4.661E-2
2.038E-1
1.000E0
 1 40
25 1270040 Bile acid and bile salt metabolism BioSystems: REACTOME 2.731E-2 4.727E-2
2.067E-1
1.000E0
 1 43
26 137911 FOXA2 and FOXA3 transcription factor networks BioSystems: Pathway Interaction Database 2.793E-2 4.727E-2
2.067E-1
1.000E0
 1 44
Show 21 more annotations

8: Pubmed [Display Chart] 9 input genes in category / 2249 annotations before applied cutoff / 38193 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 22516433 Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability. Pubmed 2.340E-8 1.850E-5 1.535E-4 5.262E-5 4 143
2 14718574 The human plasma proteome: a nonredundant list developed by combination of four separate sources. Pubmed 4.263E-8 1.850E-5 1.535E-4 9.588E-5 4 166
3 10947975 Fetuin-B, a second member of the fetuin family in mammals. Pubmed 4.936E-8 1.850E-5 1.535E-4 1.110E-4 2 2
4 3795040 Interaction between human serum albumin and alpha 1-acid glycoprotein in the binding of lidocaine to purified protein fractions and sera. Pubmed 4.936E-8 1.850E-5 1.535E-4 1.110E-4 2 2
5 28183456 Regulation of the novel adipokines/ hepatokines fetuin A and fetuin B in gestational diabetes mellitus. Pubmed 4.936E-8 1.850E-5 1.535E-4 1.110E-4 2 2
6 12943536 Tissue distribution and activity testing suggest a similar but not identical function of fetuin-B and fetuin-A. Pubmed 4.936E-8 1.850E-5 1.535E-4 1.110E-4 2 2
7 17330941 Enhanced analysis of the mouse plasma proteome using cysteine-containing tryptic glycopeptides. Pubmed 1.192E-7 3.330E-5 2.762E-4 2.682E-4 3 44
8 24359035 Differential interactions and structural stability of chitosan oligomers with human serum albumin and α-1-glycoprotein. Pubmed 1.481E-7 3.330E-5 2.762E-4 3.330E-4 2 3
9 17301560 HIV-1 Tat reduces nephrin in human podocytes: a potential mechanism for enhanced glomerular permeability in HIV-associated nephropathy. Pubmed 1.481E-7 3.330E-5 2.762E-4 3.330E-4 2 3
10 8835525 Linkage between vitamin D-binding protein and alpha-fetoprotein in the mouse. Pubmed 1.481E-7 3.330E-5 2.762E-4 3.330E-4 2 3
11 16874800 Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis. Pubmed 2.961E-7 6.054E-5 5.022E-4 6.659E-4 2 4
12 27430022 A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes. Pubmed 4.934E-7 9.248E-5 7.671E-4 1.110E-3 2 5
13 21241806 Role of Neph2 in pontine nuclei formation in the developing hindbrain. Pubmed 7.400E-7 1.280E-4 1.062E-3 1.664E-3 2 6
14 12424224 NEPH1 defines a novel family of podocin interacting proteins. Pubmed 1.381E-6 2.071E-4 1.718E-3 3.106E-3 2 8
15 18752272 Expression of kin of irregular chiasm-like 3/mKirre in proprioceptive neurons of the dorsal root ganglia and its interaction with nephrin in muscle spindles. Pubmed 1.381E-6 2.071E-4 1.718E-3 3.106E-3 2 8
16 19423573 A protein interaction network for the large conductance Ca(2+)-activated K(+) channel in the mouse cochlea. Pubmed 4.805E-6 4.653E-4 3.860E-3 1.081E-2 3 149
17 19968565 Parathyroid hormone regulates fetal-placental mineral homeostasis. Pubmed 5.175E-6 4.653E-4 3.860E-3 1.164E-2 2 15
18 16502470 Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Pubmed 6.062E-6 4.653E-4 3.860E-3 1.363E-2 3 161
19 15174051 An investigation into the human serum "interactome". Pubmed 6.176E-6 4.653E-4 3.860E-3 1.389E-2 3 162
20 18624398 Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways. Pubmed 8.329E-6 4.653E-4 3.860E-3 1.873E-2 3 179
21 16335952 Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. Pubmed 2.455E-5 4.653E-4 3.860E-3
5.521E-2
 3 257
22 22703881 Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. Pubmed 2.596E-5 4.653E-4 3.860E-3
5.839E-2
 2 33
23 16740002 Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry. Pubmed 4.028E-5 4.653E-4 3.860E-3
9.060E-2
 2 41
24 14760718 Screening for N-glycosylated proteins by liquid chromatography mass spectrometry. Pubmed 5.307E-5 4.653E-4 3.860E-3
1.193E-1
 2 47
25 12754519 Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry. Pubmed 1.216E-4 4.653E-4 3.860E-3
2.735E-1
 2 71
26 22079093 Proteomic analysis of the 20S proteasome (PSMA3)-interacting proteins reveals a functional link between the proteasome and mRNA metabolism. Pubmed 2.088E-4 4.653E-4 3.860E-3
4.697E-1
 2 93
27 27559042 Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation. Pubmed 2.272E-4 4.653E-4 3.860E-3
5.109E-1
 2 97
28 18065755 Marked defects in the expression and glycosylation of alpha2-HS glycoprotein/fetuin-A in plasma from neonates with intrauterine growth restriction: proteomics screening and potential clinical implications. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
29 26971858 The interaction and binding of flavonoids to human serum albumin modify its conformation, stability and resistance against aggregation and oxidative injuries. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
30 2415977 Human group-specific component (Gc) is a member of the albumin family. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
31 18372326 Vitamin D-binding protein influences total circulating levels of 1,25-dihydroxyvitamin D3 but does not directly modulate the bioactive levels of the hormone in vivo. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
32 11814462 Influence of the ORM1 phenotypes on serum unbound concentration and protein binding of quinidine. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
33 24139065 Cathepsin B as a potential prognostic and therapeutic marker for human lung squamous cell carcinoma. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
34 15149953 Postexercise protein metabolism in older and younger men following moderate-intensity aerobic exercise. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
35 19302999 Common genetic variants of the vitamin D binding protein (DBP) predict differences in response of serum 25-hydroxyvitamin D [25(OH)D] to vitamin D supplementation. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
36 16201370 [The interaction of vitamin B6 with the human serum albumin]. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
37 21997768 A fluorescent fatty acid probe, DAUDA, selectively displaces two myristates bound in human serum albumin. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
38 1373325 Human alpha 2-HS-glycoprotein/bovine fetuin homologue in mice: identification and developmental regulation of the gene. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
39 18085392 Evaluation of serum fetuin-A relationships with biochemical parameters in patients on hemodialysis. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
40 25019475 IMA and IMAR in serum and saliva of preeclampsia--a preliminary study. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
41 28862714 Serum albumin levels in relation to tumor parameters in hepatocellular carcinoma patients. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
42 28377509 Genetic tracing of hepatocytes in liver homeostasis, injury, and regeneration. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
43 11228542 Imaging proteolysis by living human breast cancer cells. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
44 22101880 An AHSG gene variant modulates basal metabolic rate and body composition development after a short-time lifestyle intervention. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
45 25775261 Evaluation of cord blood ischemia modified albumin in normal pregnancies and pre-eclampsia. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
46 656055 Lysine residue 240 of human serum albumin is involved in high-affinity binding of bilirubin. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
47 18476627 [Expression and clinical significance of stromelysin-3 in laryngeal cancer]. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
48 12677446 Involvement of cathepsin B in the motor neuron degeneration of amyotrophic lateral sclerosis. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
49 16337614 Ischemia-modified albumin increases after skeletal muscle ischemia during arthroscopic knee surgery. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
50 30060600 Impact of Fetuin-A (AHSG) on Tumor Progression and Type 2 Diabetes. Pubmed 2.356E-4 4.653E-4 3.860E-3
5.300E-1
 1 1
Show 45 more annotations

9: Interaction [Display Chart] 9 input genes in category / 313 annotations before applied cutoff / 17703 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 int:DDX31 DDX31 interactions 1.439E-7 4.504E-5 2.849E-4 4.504E-5 4 105
2 int:GDPD1 GDPD1 interactions 3.298E-7 5.161E-5 3.265E-4 1.032E-4 3 29
3 int:ALB ALB interactions 2.403E-6 2.507E-4 1.586E-3 7.522E-4 4 212
4 int:SNX27 SNX27 interactions 7.320E-6 5.728E-4 3.623E-3 2.291E-3 3 80
5 int:CST3 CST3 interactions 1.512E-5 9.468E-4 5.988E-3 4.734E-3 2 12
6 int:CUBN CUBN interactions 2.404E-5 1.254E-3 7.933E-3 7.525E-3 2 15
7 int:ORM1 ORM1 interactions 3.500E-5 1.530E-3 9.679E-3 1.096E-2 2 18
8 int:NPHS1 NPHS1 interactions 3.911E-5 1.530E-3 9.679E-3 1.224E-2 2 19
9 int:AHSG AHSG interactions 6.851E-5 2.383E-3 1.507E-2 2.144E-2 2 25
10 int:KCNMA1 KCNMA1 interactions 9.900E-5 3.099E-3 1.960E-2 3.099E-2 3 191
11 int:CA8 CA8 interactions 1.203E-4 3.424E-3 2.166E-2 3.766E-2 2 33
12 int:HBA2 HBA2 interactions 3.243E-4 8.459E-3
5.350E-2
1.015E-1
 2 54
13 int:DMWD DMWD interactions 4.140E-4 9.967E-3
6.304E-2
1.296E-1
 2 61
14 int:NPHS2 NPHS2 interactions 4.557E-4 1.019E-2
6.444E-2
1.426E-1
 2 64
15 int:POTEF POTEF interactions 4.994E-4 1.042E-2
6.591E-2
1.563E-1
 2 67
16 int:LRP2 LRP2 interactions 6.591E-4 1.178E-2
7.454E-2
2.063E-1
 2 77
17 int:APOE APOE interactions 7.653E-4 1.178E-2
7.454E-2
2.395E-1
 2 83
18 int:OR3A2 OR3A2 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
19 int:CACNA1I CACNA1I interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
20 int:PRB3 PRB3 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
21 int:OR2T6 OR2T6 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
22 int:OR8D2 OR8D2 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
23 int:CHKB CHKB interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
24 int:KIRREL3 KIRREL3 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
25 int:PLA2G4F PLA2G4F interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
26 int:PF4V1 PF4V1 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
27 int:GJC2 GJC2 interactions 1.017E-3 1.178E-2
7.454E-2
3.182E-1
 1 2
28 int:MAPK6 MAPK6 interactions 1.176E-3 1.315E-2
8.315E-2
3.681E-1
 3 444
29 int:MMP11 MMP11 interactions 1.524E-3 1.479E-2
9.356E-2
4.772E-1
 1 3
30 int:FETUB FETUB interactions 1.524E-3 1.479E-2
9.356E-2
4.772E-1
 1 3
31 int:SPATA31A7 SPATA31A7 interactions 1.524E-3 1.479E-2
9.356E-2
4.772E-1
 1 3
32 int:PRSS3P2 PRSS3P2 interactions 1.524E-3 1.479E-2
9.356E-2
4.772E-1
 1 3
33 int:PIK3R3 PIK3R3 interactions 1.751E-3 1.479E-2
9.356E-2
5.481E-1
 2 126
34 int:AMPD3 AMPD3 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
35 int:DGKG DGKG interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
36 int:IGDCC4 IGDCC4 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
37 int:CAMTA1 CAMTA1 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
38 int:SLC9A8 SLC9A8 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
39 int:APOC2 APOC2 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
40 int:CRB1 CRB1 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
41 int:PDZRN4 PDZRN4 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
42 int:CFD CFD interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
43 int:SRPX2 SRPX2 interactions 2.032E-3 1.479E-2
9.356E-2
6.361E-1
 1 4
44 int:CLCA2 CLCA2 interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
45 int:USP29 USP29 interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
46 int:FAM71E2 FAM71E2 interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
47 int:IGL IGL interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
48 int:TTPAL TTPAL interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
49 int:APOA4 APOA4 interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
50 int:IGKV2-40 IGKV2-40 interactions 2.540E-3 1.590E-2
1.006E-1
7.949E-1
 1 5
Show 45 more annotations

10: Cytoband [Display Chart] 9 input genes in category / 8 annotations before applied cutoff / 34661 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 3q27 3q27 1.792E-5 1.434E-4 3.897E-4 1.434E-4 2 25
2 4q12-q13 4q12-q13 5.193E-4 2.077E-3 5.644E-3 4.154E-3 1 2
3 9q31-q32 9q31-q32 7.788E-4 2.077E-3 5.644E-3 6.230E-3 1 3
4 11q24 11q24 4.406E-3 8.812E-3 2.395E-2 3.525E-2 1 17
5 8p22 8p22 1.060E-2 1.419E-2 3.857E-2
8.478E-2
 1 41
6 4q13.3 4q13.3 1.137E-2 1.419E-2 3.857E-2
9.095E-2
 1 44
7 22q11.23 22q11.23 1.394E-2 1.419E-2 3.857E-2
1.115E-1
 1 54
8 19q13.1 19q13.1 1.419E-2 1.419E-2 3.857E-2
1.135E-1
 1 55
Show 3 more annotations

11: Transcription Factor Binding Site [Display Chart] 7 input genes in category / 60 annotations before applied cutoff / 9770 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 V$HNF1 01 V$HNF1 01 2.622E-4 1.573E-2
7.364E-2
 1.573E-2 3 196
2 V$CDP 01 V$CDP 01 1.191E-3 3.573E-2
1.672E-1
7.146E-2
 2 75

12: Gene Family [Display Chart] 7 input genes in category / 9 annotations before applied cutoff / 18194 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 968 Cystatins, type 4 genenames.org 3.806E-7 3.425E-6 9.690E-6 3.425E-6 2 3
2 592 Butyrophilins|V-set domain containing|C2-set domain containing genenames.org 9.828E-5 4.423E-4 1.251E-3 8.846E-4 2 40
3 594 Immunoglobulin like domain containing|Interleukin receptors|TIR domain containing genenames.org 2.270E-3 6.810E-3 1.926E-2 2.043E-2 2 193
4 470 Cathepsins genenames.org 5.758E-3 1.296E-2 3.665E-2
5.182E-2
 1 15
5 631 Lipocalins genenames.org 7.288E-3 1.312E-2 3.711E-2
6.560E-2
 1 19
6 891 Matrix metallopeptidases genenames.org 9.199E-3 1.380E-2 3.903E-2
8.279E-2
 1 24
Show 1 more annotation

13: Coexpression [Display Chart] 9 input genes in category / 777 annotations before applied cutoff / 23137 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 18218118-Table3 Mouse Pancreas Thakur08 72genes GeneSigDB 5.347E-7 4.155E-4 3.005E-3 4.155E-4 3 44
2 15643601-Table6 Human Pancreas Centeno05 11genes GeneSigDB 7.384E-6 2.869E-3 2.075E-2 5.738E-3 2 11
3 M11507 Genes up-regulated during transition from L1 (non-tumor, infected with HCV) to G1 (well differentiated tumor, infected with HCV) in the development of hepatocellular carcinoma. MSigDB C2: CGP Curated Gene Sets (v6.0) 4.016E-5 1.040E-2
7.525E-2
 3.121E-2 2 25
4 14768006-SuppTable4 Human Breast Kim04 273genes GeneSigDB 5.377E-5 1.044E-2
7.555E-2
 4.178E-2 3 203
5 M13283 Liver selective genes MSigDB C2: CGP Curated Gene Sets (v6.0) 9.286E-5 1.443E-2
1.044E-1
7.215E-2
 3 244
6 M2219 Proteins identified in complex with PML [GeneID=5371] in K562 cells (lymphoblast). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.149E-4 1.488E-2
1.076E-1
8.926E-2
 2 42
7 16247463-Table2 Human Liver Lau06 50genes GeneSigDB 1.441E-4 1.599E-2
1.157E-1
1.120E-1
 2 47
8 M6977 Genes up-regulated in primary fibroblast cell culture at 30 min time point after infection with HCMV (AD169 strain). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.976E-4 1.769E-2
1.280E-1
1.535E-1
 2 55
9 16269622-Table1 Mouse StemCell Biswas06 71genes GeneSigDB 2.049E-4 1.769E-2
1.280E-1
1.592E-1
 2 56
10 M7534 Genes down-regulated in hepatocellular carcinoma (HCC) samples from patients with early recurrence (within 2 years after surgery) after resection. MSigDB C2: CGP Curated Gene Sets (v6.0) 2.762E-4 2.146E-2
1.553E-1
2.146E-1
 2 65
11 17638894-Table1 Mouse Breast Piechocki07 120genes Gefitinib GeneSigDB 7.748E-4 4.996E-2
3.614E-1
6.020E-1
 2 109
12 19930681-Table2-4 Human Breast Cecco09 2genes GeneSigDB 7.778E-4 4.996E-2
3.614E-1
6.044E-1
 1 2
13 M1687 Proteins secreted in co-culture of LKR-13 tumor cells (non-small cell lung cancer, NSCLC) and MLg stroma cells (fibroblasts). MSigDB C2: CGP Curated Gene Sets (v6.0) 1.133E-3 4.996E-2
3.614E-1
8.802E-1
 2 132
14 M5946 Genes encoding components of blood coagulation system; also up-regulated in platelets. MSigDB H: Hallmark Gene Sets (v6.0) 1.237E-3 4.996E-2
3.614E-1
9.612E-1
 2 138
15 M2902 Genes up-regulated in epithelial prostate cancer cell lines over-expressing an oncogenic form of KRAS [Gene ID=3845] gene. MSigDB C6: Oncogenic Signatures (v6.0) 1.273E-3 4.996E-2
3.614E-1
9.890E-1
 2 140
16 17683518-193GeneTable Human Breast Teschendorff07 193genes Erpos GeneSigDB 1.846E-3 4.996E-2
3.614E-1
1.000E0
 2 169
17 M1794 Protease genes down-regulated at tumor-bone interface compared to the tumor alone area. MSigDB C2: CGP Curated Gene Sets (v6.0) 1.944E-3 4.996E-2
3.614E-1
1.000E0
 1 5
18 M2765 Genes down-regulated during late stages of differentiation of embryoid bodies from J1 embryonic stem cells. MSigDB C6: Oncogenic Signatures (v6.0) 2.230E-3 4.996E-2
3.614E-1
1.000E0
 2 186
19 M6215 Genes down-regulated in polymorphonuclear leukocytes (6h): control versus infection by A. phagocytophilum. MSigDB C7: Immunologic Signatures (v6.0) 2.373E-3 4.996E-2
3.614E-1
1.000E0
 2 192
20 M9706 Genes down-regulated in CD4 [GeneID=920] Th1 cells: wildtype versus EGR2 [GeneID=1959] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.422E-3 4.996E-2
3.614E-1
1.000E0
 2 194
21 M7281 Top 200 genes with high histone H3 trimethylation mark at K27 (H3K27me3) in PC3 cells (prostate cancer), by ChIP-chip assay on an 88K microarray (all promoters). MSigDB C2: CGP Curated Gene Sets (v6.0) 2.472E-3 4.996E-2
3.614E-1
1.000E0
 2 196
22 M8875 Genes up-regulated in hematopoietic stem cells versus common lymphoid progenitors. MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 4.996E-2
3.614E-1
1.000E0
 2 197
23 M8856 Genes down-regulated in lymphoid primed multipotent progenitors versus pro-B cells. MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 4.996E-2
3.614E-1
1.000E0
 2 197
24 M5217 Genes up-regulated in comparison of dendritic cells (DC) exposed to T. gondii versus DCs exposed to 5 worms/well B. malayi. MSigDB C7: Immunologic Signatures (v6.0) 2.497E-3 4.996E-2
3.614E-1
1.000E0
 2 197
25 M8347 Genes up-regulated in germinal center B lymphocytes: wildtype versus ZBTB7A [GeneID=51341] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.521E-3 4.996E-2
3.614E-1
1.000E0
 2 198
26 M8335 Genes down-regulated in BCL6 [GeneID=604] high follicular helper T cells versus T conv cells. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 4.996E-2
3.614E-1
1.000E0
 2 199
27 M8398 Genes down-regulated in brain microglia versus spleen CD8+ dendritic cells. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 4.996E-2
3.614E-1
1.000E0
 2 199
28 M8361 Genes up-regulated in T reg: natural versus induced cells. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 4.996E-2
3.614E-1
1.000E0
 2 199
29 M8343 Genes up-regulated in activated versus induced T reg cells. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 4.996E-2
3.614E-1
1.000E0
 2 199
30 M3907 Genes down-regulated in comparison of dendritic cells (DC) stimulated with LPS (TLR4 agonist) at 0.5 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 0.5 h. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 4.996E-2
3.614E-1
1.000E0
 2 199
31 M8173 Genes down-regulated in HEK293 cells over-expressing wildtype NOD2 [GeneID=64127]: untreated versus muramyl dipeptide [PubChem=11620162] for 6h. MSigDB C7: Immunologic Signatures (v6.0) 2.547E-3 4.996E-2
3.614E-1
1.000E0
 2 199
32 M3846 Genes up-regulated in comparison of dendritic cells (DC) stimulated with poly(I:C) (TLR3 agonist) at 24 h versus DC cells stimulated with Pam3Csk4 (TLR1/2 agonist) at 24 h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
33 M3490 Genes up-regulated in comparison of unstimulated macrophage cells versus macrophage cells stimulated with LPS (TLR4 agonist) for 20 min. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
34 M6300 Genes up-regulated in macrophages primed and then stimulated by IFNG [GeneID=3458]: 3h versus 24h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
35 M9920 Genes down-regulated in B lymphocytes with MAP3K7 [GeneID=6885] knockout: untreated versus anti IgM for 24h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
36 M8844 Genes up-regulated in NK cells: RAG2 [GeneID=5897] knockout versus RAG2 and ETS1 [GeneID=5897;2113] knockout. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
37 M7506 Genes up-regulated in CD4 [GeneID=920] Tfh (T follicular helper) cells: Tfh versus Tfh from germinal center. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
38 M3690 Genes down-regulated in comparison of control dendritic cells (DC) at 4 h versus those stimulated with LPS (TLR4 agonist) at 4 h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
39 M3869 Genes up-regulated in comparison of dendritic cells (DC) stimulated with Pam3Csk4 (TLR1/2 agonist) at 16 h versus DC cells stimulated with CpG DNA (TLR9 agonist) at 16 h. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
40 M8337 Genes up-regulated in BCL6 [GeneID=604] high follicular helper T cells (Tfh) versus all Tfh. MSigDB C7: Immunologic Signatures (v6.0) 2.572E-3 4.996E-2
3.614E-1
1.000E0
 2 200
Show 35 more annotations

14: Coexpression Atlas [Display Chart] 9 input genes in category / 699 annotations before applied cutoff / 21829 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 liver liver Human Protein Atlas 3.009E-7 8.972E-5 6.395E-4 2.103E-4 5 419
2 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Liver Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Liver Tabula Muris Consortium 3.075E-7 8.972E-5 6.395E-4 2.150E-4 4 156
3 Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Liver/hepatocyte Tabula Muris Consortium/Tabula Muris Consortium/Tissues and cell class/Liver/hepatocyte Tabula Muris Consortium 3.851E-7 8.972E-5 6.395E-4 2.692E-4 4 165
4 ratio EB-blastocyst vs EB-cbCD34 500 K1 ratio EmbryoidBody-blastocyst vs EmbryoidBody-derived-from CD34-iPSC top-relative-expression-ranked 500 k-means-cluster#1 PCBC 7.210E-7 1.260E-4 8.980E-4 5.040E-4 4 193
5 Facebase ST1 Univ 250 UniversalReference WholeMouseP1 top-relative-expression-ranked 250 FaceBase_ST1 9.353E-7 1.308E-4 9.320E-4 6.538E-4 4 206
6 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 100 k2 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#2 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 1.189E-6 1.386E-4 9.877E-4 8.314E-4 3 54
7 BM Top 100 - liver BM Top 100 - liver Body Map 3.919E-6 3.073E-4 2.190E-3 2.739E-3 3 80
8 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 100 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 100 Gudmap Mouse MOE430.2 3.919E-6 3.073E-4 2.190E-3 2.739E-3 3 80
9 ratio EB-blastocyst vs EB-cbCD34 1000 K2 ratio EmbryoidBody-blastocyst vs EmbryoidBody-derived-from CD34-iPSC top-relative-expression-ranked 1000 k-means-cluster#2 PCBC 3.957E-6 3.073E-4 2.190E-3 2.766E-3 4 296
10 Facebase ST1 Univ 100 UniversalReference WholeMouseP1 top-relative-expression-ranked 100 FaceBase_ST1 4.541E-6 3.174E-4 2.262E-3 3.174E-3 3 84
11 PCBC EB blastocyst 100 Progenitor-Cell-Biology-Consortium EmbryoidBody fromBlastocyst-derived-humanEmbryonicStemCells top-relative-expression-ranked 100 PCBC 7.681E-6 4.881E-4 3.479E-3 5.369E-3 3 100
12 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 200 k3 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#3 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 1.139E-5 6.634E-4 4.729E-3 7.961E-3 3 114
13 Facebase ST1 Univ 500 UniversalReference WholeMouseP1 top-relative-expression-ranked 500 FaceBase_ST1 1.683E-5 9.049E-4 6.450E-3 1.176E-2 4 427
14 PCBC ratio EB-blastocyst vs EB-cbCD34 500 ratio EmbryoidBody-blastocyst vs EmbryoidBody-derived-from CD34-iPSC top-relative-expression-ranked 500 PCBC 2.798E-5 1.397E-3 9.958E-3 1.956E-2 4 486
15 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 200 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 200 Gudmap Mouse MOE430.2 3.262E-5 1.520E-3 1.083E-2 2.280E-2 3 162
16 Facebase ST1 Univ 500 2 UniversalReference WholeMouseP1 top-relative-expression-ranked 500 2 FaceBase_ST1 7.926E-5 3.463E-3 2.468E-2
5.540E-2
 2 33
17 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 500 k2 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#2 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 1.130E-4 4.644E-3 3.310E-2
7.896E-2
 3 246
18 Sample Type by Project: Shred 1/TCGA-Liver/Hepatocellular Carcinoma/Hepatocellular Carcinoma/2/0 Sample Type by Project: Shred 1/TCGA-Liver/Hepatocellular Carcinoma/Hepatocellular Carcinoma/2/0 TCGA-Liver 1.549E-4 6.016E-3 4.288E-2
1.083E-1
 2 46
19 gudmap developingLowerUrinaryTract e14.5 Genital tubercle 1000 k4 DevelopingLowerUrinaryTract e14.5 Genital tubercle emap-6706 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 1.759E-4 6.472E-3 4.613E-2
1.230E-1
 2 49
20 PCBC ratio MESO-30 blastocyst vs MESO-30 fibroblast cfr-2X-p05 MESO-30 blastocyst vs MESO-30 fibroblast-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 3.912E-4 1.226E-2
8.742E-2
2.734E-1
 3 375
21 PCBC ratio MESO-30 from-ESC vs MESO-30 from-OSKM - NLT cfr-2X-p05 Mesoderm Day 30-reprogram NA vs Mesoderm Day 30-reprogram OSKM - NLT-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 3.912E-4 1.226E-2
8.742E-2
2.734E-1
 3 375
22 PCBC ratio MESO-30 from-ESC vs MESO-30 from-plasmid cfr-2X-p05 Mesoderm Day 30-method NA vs Mesoderm Day 30-method plasmid-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 3.912E-4 1.226E-2
8.742E-2
2.734E-1
 3 375
23 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 1000 k4 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 k-means-cluster#4 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 4.035E-4 1.226E-2
8.742E-2
2.821E-1
 3 379
24 ratio EB-blastocyst vs EB-cbCD34 2500 K3 ratio EmbryoidBody-blastocyst vs EmbryoidBody-derived-from CD34-iPSC top-relative-expression-ranked 2500 k-means-cluster#3 PCBC 4.454E-4 1.297E-2
9.247E-2
3.114E-1
 3 392
25 gudmap developingLowerUrinaryTract e15.5 ureteral tissue 500 DevelopingLowerUrinaryTract e15.5 ureteral tissue emap-8234 top-relative-expression-ranked 500 Gudmap Mouse MOE430.2 4.936E-4 1.359E-2
9.684E-2
3.450E-1
 3 406
26 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Rectal Adenocarcinoma/5/0 Sample Type by Project: Shred 1/TCGA-Colorectal/Colorectal Adenocarcinoma/Rectal Adenocarcinoma/5/0 TCGA-Colorectal 5.054E-4 1.359E-2
9.684E-2
3.533E-1
 2 83
27 gudmap kidney adult JuxtaGlom Ren1 k1 1000 kidney adult JuxtaGlom Ren1 k-means-cluster#1 top-relative-expression-ranked 1000 Gudmap Mouse MOE430.2 5.939E-4 1.538E-2
1.096E-1
4.151E-1
 2 90
28 ratio EB-blastocyst vs EB-fibro 500 K3 ratio EmbryoidBody-blastocyst vs EmbryoidBody-fibro top-relative-expression-ranked 500 k-means-cluster#3 PCBC 7.036E-4 1.733E-2
1.235E-1
4.918E-1
 2 98
29 PCBC EB 100 Progenitor-Cell-Biology-Consortium EmbryoidBody top-relative-expression-ranked 100 PCBC 7.325E-4 1.733E-2
1.235E-1
5.120E-1
 2 100
30 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK4 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney NK cell/Kidney Tumour Wilms NK cell/Kidney Tumour Wilms NK4 Adult, Development, and Cancer types 8.244E-4 1.733E-2
1.235E-1
5.763E-1
 1 2
31 Sample Type by Project: Shred 1/TCGA-Stomach/Stomach Adenocarcinoma/Stomach Adenocarcinoma - Diffuse/5/4 Sample Type by Project: Shred 1/TCGA-Stomach/Stomach Adenocarcinoma/Stomach Adenocarcinoma - Diffuse/5/4 TCGA-Stomach 8.379E-4 1.733E-2
1.235E-1
5.857E-1
 2 107
32 ratio SC-fibro vs SC-cbCD34 1000 K3 ratio StemCell-fibro vs StemCell-derived-from CD34-iPSC top-relative-expression-ranked 1000 k-means-cluster#3 PCBC 8.535E-4 1.733E-2
1.235E-1
5.966E-1
 2 108
33 PCBC ratio SC-fibro vs SC-cbCD34 500 ratio StemCell-fibro vs StemCell-derived-from CD34-iPSC top-relative-expression-ranked 500 PCBC 8.537E-4 1.733E-2
1.235E-1
5.967E-1
 3 490
34 PCBC EB blastocyst 500 Progenitor-Cell-Biology-Consortium EmbryoidBody fromBlastocyst-derived-humanEmbryonicStemCells top-relative-expression-ranked 500 PCBC 8.948E-4 1.733E-2
1.235E-1
6.255E-1
 3 498
35 PCBC EB fibroblast 500 Progenitor-Cell-Biology-Consortium EmbryoidBody from inducedPluripotentialStemCells derived from from fibroblast top-relative-expression-ranked 500 PCBC 9.000E-4 1.733E-2
1.235E-1
6.291E-1
 3 499
36 PCBC EB 500 Progenitor-Cell-Biology-Consortium EmbryoidBody top-relative-expression-ranked 500 PCBC 9.000E-4 1.733E-2
1.235E-1
6.291E-1
 3 499
37 ratio SC-fibro vs SC-cbCD34 500 K2 ratio StemCell-fibro vs StemCell-derived-from CD34-iPSC top-relative-expression-ranked 500 k-means-cluster#2 PCBC 9.174E-4 1.733E-2
1.235E-1
6.413E-1
 2 112
38 Facebase RNAseq ratio e9.5 MaxillaryArch vs Mandibular 1000 K5 FacebaseRNAseq ratio e9.5 MaxillaryArch vs Mandibular top-relative-expression-ranked 1000 k-means-cluster#5 FaceBase_RNAseq 1.196E-3 2.176E-2
1.551E-1
8.357E-1
 2 128
39 Sample Type by Project: Shred 1/TCGA-Uterus/Uterine Carcinoma/Uterine Carcinosarcoma Heterologous Type/1/1 Sample Type by Project: Shred 1/TCGA-Uterus/Uterine Carcinoma/Uterine Carcinosarcoma Heterologous Type/1/1 TCGA-Uterus 1.214E-3 2.176E-2
1.551E-1
8.487E-1
 2 129
40 ratio EB-blastocyst vs EB-fibro 1000 K3 ratio EmbryoidBody-blastocyst vs EmbryoidBody-fibro top-relative-expression-ranked 1000 k-means-cluster#3 PCBC 1.252E-3 2.187E-2
1.559E-1
8.749E-1
 2 131
41 Sample Type by Project: Shred 1/TCGA-Kidney/Renal Cell Carcinoma/Kidney Clear Cell Renal Carcinoma/3/0 Sample Type by Project: Shred 1/TCGA-Kidney/Renal Cell Carcinoma/Kidney Clear Cell Renal Carcinoma/3/0 TCGA-Kidney 1.658E-3 2.826E-2
2.014E-1
1.000E0
 2 151
42 Sample Type by Project: Shred 1/TCGA-Cervix/Cervical Carcinoma/Keratinizing Cervical Squamous Cell Carcinoma/1/1 Sample Type by Project: Shred 1/TCGA-Cervix/Cervical Carcinoma/Keratinizing Cervical Squamous Cell Carcinoma/1/1 TCGA-Cervix 1.701E-3 2.831E-2
2.018E-1
1.000E0
 2 153
43 Sample Type by Project: Shred 1/TCGA-Bile Duct/Cholangiocarcinoma/Hilar/Perihilar/5 Sample Type by Project: Shred 1/TCGA-Bile Duct/Cholangiocarcinoma/Hilar/Perihilar/5 TCGA-Bile Duct 1.974E-3 3.210E-2
2.288E-1
1.000E0
 2 165
44 BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Endothelial Tip/Endothelial Tip/Endothelial Tip/Dcn//Nenf BrainMap/BrainAtlas - Mouse McCarroll/Lineage to Cells - regions (clevel sub)/Endothelial Tip/Endothelial Tip/Endothelial Tip/Dcn//Nenf BrainMap 2.046E-3 3.250E-2
2.316E-1
1.000E0
 2 168
45 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Seminoma- NOS/7 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Seminoma- NOS/7 TCGA-Testes 2.118E-3 3.290E-2
2.345E-1
1.000E0
 2 171
46 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Non-Seminoma- Yolk Sac Tumor/6 Sample Type by Project: Shred 1/TCGA-Testes/Testicular Germ Cell Tumor/Non-Seminoma- Yolk Sac Tumor/6 TCGA-Testes 2.217E-3 3.369E-2
2.401E-1
1.000E0
 2 175
47 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal VHL RCC R U/Kidney Normal VHL RCC R12 Human Kidney Cell Atlas/Human/Adult, Development, and Cancer types/Cell Type of Cell Class of Tissue/Kidney R U/Kidney Normal VHL RCC R U/Kidney Normal VHL RCC R12 Adult, Development, and Cancer types 2.343E-3 3.453E-2
2.461E-1
1.000E0
 2 180
48 PCBC ratio MESO-15 from-ESC vs MESO-15 from-OSK-L-l-p53KD cfr-2X-p05 Mesoderm Day 15-reprogram NA vs Mesoderm Day 15-reprogram OSK-L-l-p53KD-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.421E-3 3.453E-2
2.461E-1
1.000E0
 2 183
49 PCBC ratio MESO-15 from-ESC vs MESO-15 from-episomal cfr-2X-p05 Mesoderm Day 15-method NA vs Mesoderm Day 15-method episomal-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.421E-3 3.453E-2
2.461E-1
1.000E0
 2 183
50 PCBC ratio iPSC method-OSK-l-p53KD vs ESC cfr-2X-p05 Pluripotent Stem Cells-reprogram OSK-l-p53KD vs Pluripotent Stem Cells-reprogram NA-Confounder removed-fold2.0 adjp0.05 PCBC_AltAnalyze 2.472E-3 3.455E-2
2.463E-1
1.000E0
 1 6
Show 45 more annotations

15: Computational [Display Chart] 9 input genes in category / 69 annotations before applied cutoff / 10037 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 M14108 GNF2 HPX Neighborhood of HPX MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.744E-6 2.583E-4 1.245E-3 2.583E-4 4 135
2 M5702 MODULE 24 Fetal liver genes - metabolism and xenobiotics. MSigDb: C4 - CM: Cancer Modules (v6.0) 1.986E-5 6.850E-4 3.301E-3 1.370E-3 5 453
3 M132 GNF2 LCAT Neighborhood of LCAT MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.464E-4 3.109E-3 1.498E-2 1.010E-2 3 124
4 M10917 GNF2 HPN Neighborhood of HPN MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.803E-4 3.109E-3 1.498E-2 1.244E-2 3 133
5 M18034 CAR IGFBP1 Neighborhood of IGFBP1 MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.112E-3 1.534E-2
7.394E-2
7.672E-2
 2 57
6 M6913 CAR HPX Neighborhood of HPX MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 1.817E-3 2.090E-2
1.007E-1
1.254E-1
 2 73
7 M17376 MODULE 107 Genes in the cancer module 107. MSigDb: C4 - CM: Cancer Modules (v6.0) 2.125E-3 2.094E-2
1.009E-1
1.466E-1
 2 79
8 M10041 MODULE 172 Genes in the cancer module 172. MSigDb: C4 - CM: Cancer Modules (v6.0) 3.120E-3 2.691E-2
1.297E-1
2.153E-1
 2 96
9 M17919 GNF2 TST Neighborhood of TST MSigDb: C4 - CGN: Cancer Gene Neighborhood (v6.0) 3.651E-3 2.799E-2
1.349E-1
2.519E-1
 2 104
Show 4 more annotations

16: MicroRNA [Display Chart] 9 input genes in category / 87 annotations before applied cutoff / 72241 genes in category

No results to display

17: Drug [Display Chart] 9 input genes in category / 3171 annotations before applied cutoff / 22841 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 CID006398363 2 HR Stitch 2.329E-11 7.384E-8 6.379E-7 7.384E-8 5 67
2 CID000349960 Sialic acids Stitch 6.913E-10 1.096E-6 9.469E-6 2.192E-6 6 329
3 CID000123802 NeuGc Stitch 8.949E-9 9.459E-6 8.172E-5 2.838E-5 4 68
4 CID000000906 type-IV Stitch 3.292E-8 2.183E-5 1.886E-4 1.044E-4 5 281
5 CID000007322 sulfosalicylic acid Stitch 3.442E-8 2.183E-5 1.886E-4 1.091E-4 3 18
6 CID000173548 E64A Stitch 1.891E-7 9.094E-5 7.856E-4 5.996E-4 3 31
7 ctd:C101814 perfluoro-n-undecanoic acid CTD 2.007E-7 9.094E-5 7.856E-4 6.366E-4 5 404
8 CID000122618 deoxyfuconojirimycin Stitch 3.265E-7 1.294E-4 1.118E-3 1.035E-3 3 37
9 CID000163871 4-hydroxytertatolol Stitch 4.140E-7 1.351E-4 1.167E-3 1.313E-3 2 3
10 CID006450878 Etiocobalamin Stitch 4.261E-7 1.351E-4 1.167E-3 1.351E-3 4 177
11 CID005289411 ST-8 Stitch 4.819E-7 1.389E-4 1.200E-3 1.528E-3 3 42
12 CID000643990 3'-sialyl LewisX Stitch 6.538E-7 1.728E-4 1.493E-3 2.073E-3 4 197
13 CID000123914 sialyllactose Stitch 9.812E-7 2.260E-4 1.952E-3 3.111E-3 3 53
14 CID000001775 phenytoin Stitch 9.978E-7 2.260E-4 1.952E-3 3.164E-3 4 219
15 CID005473883 AC1NV8X5 Stitch 1.379E-6 2.734E-4 2.362E-3 4.374E-3 2 5
16 CID000079736 14-F Stitch 1.379E-6 2.734E-4 2.362E-3 4.374E-3 2 5
17 CID000181201 4-aminophenyl Stitch 1.581E-6 2.950E-4 2.548E-3 5.014E-3 3 62
18 CID000643988 6'SLN Stitch 2.069E-6 3.644E-4 3.148E-3 6.559E-3 2 6
19 CID000457707 AC1L9X2P Stitch 2.489E-6 4.153E-4 3.588E-3 7.892E-3 3 72
20 CID000133902 7-anilinocoumarin-4-acetic acid Stitch 2.895E-6 4.591E-4 3.966E-3 9.181E-3 2 7
21 CID000007708 pH Q Stitch 3.295E-6 4.976E-4 4.299E-3 1.045E-2 3 79
22 CID000022069 reverse T3 Stitch 3.688E-6 5.316E-4 4.593E-3 1.170E-2 3 82
23 ctd:D028321 Plant Preparations CTD 4.452E-6 6.137E-4 5.302E-3 1.412E-2 4 319
24 CID000196569 GM1 oligosaccharide Stitch 4.961E-6 6.555E-4 5.663E-3 1.573E-2 2 9
25 CID000000897 H S Q Stitch 6.499E-6 8.244E-4 7.122E-3 2.061E-2 4 351
26 ctd:C010972 glycolaldehyde CTD 7.577E-6 8.899E-4 7.688E-3 2.403E-2 2 11
27 CID003081597 KI-8110 Stitch 7.577E-6 8.899E-4 7.688E-3 2.403E-2 2 11
28 CID000006540 TBEP Stitch 9.090E-6 1.029E-3 8.894E-3 2.883E-2 2 12
29 ctd:D005035 Ethylmercury Compounds CTD 1.074E-5 1.174E-3 1.015E-2 3.406E-2 2 13
30 ctd:C031721 naphthalene CTD 1.212E-5 1.281E-3 1.107E-2 3.843E-2 4 411
31 CID000024538 ammonium sulfate Stitch 1.344E-5 1.345E-3 1.162E-2 4.261E-2 3 126
32 ctd:D001761 Bleomycin CTD 1.357E-5 1.345E-3 1.162E-2 4.305E-2 4 423
33 CID000643986 3'SLN Stitch 1.445E-5 1.389E-3 1.200E-2 4.583E-2 2 15
34 CID000189022 glucosaminitol Stitch 1.651E-5 1.455E-3 1.257E-2
5.237E-2
 2 16
35 ctd:D009930 Organic Chemicals CTD 1.651E-5 1.455E-3 1.257E-2
5.237E-2
 2 16
36 CID000643987 6'-sialyllactose Stitch 1.651E-5 1.455E-3 1.257E-2
5.237E-2
 2 16
37 CID000064951 t-Acid Stitch 1.871E-5 1.604E-3 1.385E-2
5.934E-2
 2 17
38 CID000024441 calcium phosphate Stitch 2.220E-5 1.842E-3 1.591E-2
7.041E-2
 3 149
39 CID000001593 25(OH) vitamin D3 Stitch 2.265E-5 1.842E-3 1.591E-2
7.183E-2
 3 150
40 ctd:D004923 Erythrosine CTD 2.352E-5 1.864E-3 1.611E-2
7.458E-2
 2 19
41 CID000092865 gamma-Glutamylglutamate Stitch 2.613E-5 2.021E-3 1.746E-2
8.285E-2
 2 20
42 CID000119138 thiodigalactoside Stitch 2.887E-5 2.131E-3 1.841E-2
9.155E-2
 2 21
43 CID000151956 Arginylarginine Stitch 2.904E-5 2.131E-3 1.841E-2
9.209E-2
 3 163
44 CID000000245 N-acetyllactosamine Stitch 2.958E-5 2.131E-3 1.841E-2
9.378E-2
 3 164
45 CID000036920 tertatolol Stitch 3.175E-5 2.142E-3 1.851E-2
1.007E-1
 2 22
46 ctd:D006037 Glyoxal CTD 3.175E-5 2.142E-3 1.851E-2
1.007E-1
 2 22
47 ctd:C052387 cocoa butter CTD 3.175E-5 2.142E-3 1.851E-2
1.007E-1
 2 22
48 CID000011787 4-chloro-1-naphthol Stitch 3.477E-5 2.297E-3 1.984E-2
1.102E-1
 2 23
49 ctd:C032036 bromobenzene CTD 3.904E-5 2.527E-3 2.183E-2
1.238E-1
 3 180
50 CID000104944 arene oxide Stitch 4.463E-5 2.743E-3 2.369E-2
1.415E-1
 2 26
Show 45 more annotations

18: Disease [Display Chart] 9 input genes in category / 511 annotations before applied cutoff / 16205 genes in category

ID Name Source pValue FDR B&H FDR B&Y Bonferroni Genes from Input Genes in Annotation
1 C0016395 Focal Dermal Hypoplasia DisGeNET Curated 5.750E-6 1.469E-3 1.001E-2 2.938E-3 2 7
2 C0342185 Hyperthyroxinemia, Familial Dysalbuminemic DisGeNET Curated 5.750E-6 1.469E-3 1.001E-2 2.938E-3 2 7
3 C0011436 Dentinogenesis Imperfecta DisGeNET Curated 3.277E-5 4.538E-3 3.092E-2 1.675E-2 2 16
4 C0033687 Proteinuria DisGeNET Curated 3.552E-5 4.538E-3 3.092E-2 1.815E-2 3 124
5 C4049702 Focal Segmental Glomerulosclerosis, Not Otherwise Specified DisGeNET BeFree 6.298E-5 5.347E-3 3.644E-2 3.218E-2 2 22
6 C0027720 Nephrosis DisGeNET Curated 6.895E-5 5.347E-3 3.644E-2 3.524E-2 2 23
7 C3899403 Decreased Concentration DisGeNET BeFree 7.520E-5 5.347E-3 3.644E-2 3.843E-2 2 24
8 C2711227 Steatohepatitis DisGeNET Curated 9.003E-5 5.347E-3 3.644E-2 4.600E-2 4 487
9 C0017658 Glomerulonephritis DisGeNET Curated 9.418E-5 5.347E-3 3.644E-2 4.812E-2 3 172
10 C1704321 Nephrotic Syndrome, Minimal Change DisGeNET BeFree 1.808E-4 8.347E-3
5.688E-2
9.238E-2
 2 37
11 C0239981 Hypoalbuminemia DisGeNET Curated 2.010E-4 8.347E-3
5.688E-2
1.027E-1
 2 39
12 C0017665 Membranous glomerulonephritis DisGeNET Curated 4.773E-4 8.347E-3
5.688E-2
2.439E-1
 2 60
13 C0271650 Impaired glucose tolerance DisGeNET Curated 5.001E-4 8.347E-3
5.688E-2
2.556E-1
 3 303
14 C3469186 HEMOCHROMATOSIS, TYPE 1 DisGeNET Curated 5.262E-4 8.347E-3
5.688E-2
2.689E-1
 2 63
15 C2675487 Mental Retardation, Autosomal Dominant 4 DisGeNET Curated 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
16 cv:C0403399 Finnish congenital nephrotic syndrome Clinical Variations 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
17 C0019699 HIV Seropositivity DisGeNET Curated 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
18 C0878666 Analbuminemia DisGeNET Curated 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
19 cv:C0342185 Hyperthyroxinemia, familial dysalbuminemic Clinical Variations 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
20 cv:C2675487 Mental retardation, autosomal dominant 4 Clinical Variations 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
21 C0241235 Purulent sputum DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
22 C0936251 Polyradiculitis DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
23 OMIN:612581 MENTAL RETARDATION, AUTOSOMAL DOMINANT 4; MRD4 OMIM 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
24 OMIN:256300 NEPHROTIC SYNDROME, TYPE 1; NPHS1 OMIM 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
25 cv:C0878666 Analbuminemia Clinical Variations 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
26 C1860228 ZINC, ELEVATED PLASMA DisGeNET Curated 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
27 C0037753 Sparganosis DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
28 C1320211 Invasive Group A beta-hemolytic streptococcal disease DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
29 C0599458 glycosphingolipidoses DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
30 C1863119 Dysalbuminemic Hyperthyroxinemia DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
31 C0009021 Clonorchiasis DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
32 C0730277 Moderate nonproliferative diabetic retinopathy DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
33 C1761613 Conjunctival hyperemia DisGeNET BeFree 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
34 C0020522 Delayed Hypersensitivity DisGeNET Curated 5.554E-4 8.347E-3
5.688E-2
2.838E-1
 1 1
35 C2316810 Chronic kidney disease stage 5 DisGeNET Curated 6.474E-4 9.452E-3
6.441E-2
3.308E-1
 3 331
36 C1561643 Chronic Kidney Diseases DisGeNET Curated 7.001E-4 9.937E-3
6.772E-2
3.577E-1
 3 340
37 C0022661 Kidney Failure, Chronic DisGeNET Curated 8.201E-4 1.133E-2
7.719E-2
4.191E-1
 3 359
38 C0029456 Osteoporosis DisGeNET Curated 9.381E-4 1.234E-2
8.407E-2
4.794E-1
 3 376
39 C0015695 Fatty Liver DisGeNET Curated 9.673E-4 1.234E-2
8.407E-2
4.943E-1
 3 380
40 C0278488 Carcinoma breast stage IV DisGeNET BeFree 1.043E-3 1.234E-2
8.407E-2
5.330E-1
 3 390
41 C0178664 Glomerulosclerosis (disorder) DisGeNET Curated 1.094E-3 1.234E-2
8.407E-2
5.592E-1
 2 91
42 C0334524 Mixed Germ Cell Tumor DisGeNET BeFree 1.110E-3 1.234E-2
8.407E-2
5.675E-1
 1 2
43 C1855796 Hypoproteinemia, Hypercatabolic DisGeNET Curated 1.110E-3 1.234E-2
8.407E-2
5.675E-1
 1 2
44 C1168279 melalgia DisGeNET BeFree 1.110E-3 1.234E-2
8.407E-2
5.675E-1
 1 2
45 C2750824 Dystransthyretinemic Euthyroidal Hyperthyroxinemia DisGeNET Curated 1.110E-3 1.234E-2
8.407E-2
5.675E-1
 1 2
46 C0342613 Danish type familial amyloid cardiomyopathy DisGeNET BeFree 1.110E-3 1.234E-2
8.407E-2
5.675E-1
 1 2
47 C0011615 Dermatitis, Atopic DisGeNET Curated 1.214E-3 1.320E-2
8.995E-2
6.204E-1
 3 411
48 C3160718 PARKINSON DISEASE, LATE-ONSET DisGeNET Curated 1.293E-3 1.377E-2
9.384E-2
6.610E-1
 2 99
49 C0042164 Uveitis DisGeNET Curated 1.346E-3 1.403E-2
9.564E-2
6.877E-1
 2 101
50 C0013595 Eczema DisGeNET Curated 1.459E-3 1.467E-2
9.998E-2
7.455E-1
 3 438
Show 45 more annotations